Capital Midwest Fund is a venture capital firm based in Mequon, Wisconsin. It specializes in early-stage investments across various sectors including life sciences, information technology, advanced manufacturing, B2B, and healthcare, with a focus on companies located in the Midwest region of the United States.

Cream City Venture Capital is a Milwaukee-based investment firm committed to fostering business growth in Southeastern Wisconsin. With a strong connection to the region, the firm focuses on supporting innovative startups and entrepreneurs, aiming to revitalize local neighborhoods and enhance the community's economic landscape. By leveraging its extensive network and resources, Cream City Venture Capital seeks to drive positive change and create opportunities for sustainable development in the area. The firm embodies a commitment to the region's long-term growth, ensuring that Milwaukee continues to be an attractive place for talent and investment.

Venture Investors is a Midwest-based venture capital firm that funds seed, early, and growth-stage startups and provides incubation financing. It concentrates on university technology transfer opportunities, particularly in the Midwest, and invests across healthcare, life sciences, agriculture, technology, clean tech, materials, energy, and hardware, including software and digital health. The firm backs companies licensed to research universities, including institutions such as the University of Wisconsin–Madison, and seeks opportunities with significant market potential and solid fundamentals. Seed investments typically range from 0.25 million to 2.5 million, with larger follow-ons possible, and the firm aims to lead rounds while also co-investing. It favors preferred equity and/or debt with warrant coverage and pursues exits through initial public offerings or sales after about five to seven years. Established in 1982, Venture Investors is headquartered in Madison, Wisconsin, with additional offices in Ann Arbor, Michigan, and Milwaukee, Wisconsin.

Established in 2002, Golden Angels Investors is an angel investment group based in Brookfield, Wisconsin. Its members, with a track record of business success, invest directly or participate in opportunities led by other investors to assist entrepreneurs in building great companies, primarily focusing on health tech, ed-tech, and B2B services.

Silicon Pastures LLC is an angel investment network based in Milwaukee, Wisconsin, founded in 2000. The firm focuses on investing in technology-driven companies that address specific challenges, primarily in the Midwest region of the United States. Silicon Pastures comprises a group of angel investors who convene monthly to evaluate business proposals and conduct due diligence on potential investments. The firm typically looks for companies with a minimum of $200,000 in revenue, although it is willing to consider earlier-stage opportunities. Additionally, Silicon Pastures aims to assist its portfolio companies in expanding their operations globally and maintains an office in South Korea to facilitate this growth.

Founded in 2006, New Capital Fund is a venture capital firm based in Little Chute, Wisconsin. It focuses on investing in seed-stage to growth-stage companies across various sectors including business products/services, materials/resources, healthcare, information technology, advanced manufacturing, life sciences, and TMT.

Founded in 2013, WISC Partners is a venture capital firm based in Madison, Wisconsin. It invests in technology-enabled services, industrial technology, agricultural technology, healthcare innovation, and technology sectors with the goal of building wealth by supporting entrepreneurs who can create great companies that solve significant customer problems.

Founded in 2019, TitletownTech is an early-stage venture capital firm based in Green Bay, Wisconsin. It invests in bold entrepreneurs solving meaningful problems across six verticals: sports, media & entertainment; digital health; agriculture, water & environment; manufacturing & construction; supply chain & logistics; and cross-industry technology, with a focus on the Midwest.

Founded in 2013, CSA Partners is a venture capital firm based in Milwaukee, Wisconsin. It specializes in early-stage and high-growth investments, primarily focusing on companies in the Midwest region.

Rock River Capital Partners is a Midwest-based venture capital firm based in Madison, Wisconsin, that funds early-stage and growth companies across sectors, with a focus on technology-driven businesses such as software. It seeks ventures with initial product-market fit and strong growth potential, and often emphasizes disruptive innovations. The firm aims to be the lead investor and regularly takes a board seat to add value while keeping deal terms straightforward and founder-friendly. It reserves capital for follow-on investments to support portfolio companies through subsequent rounds and collaborates with other large Midwest venture investors to help portfolio companies reach the next level of funding. The emphasis is on hands-on partnership with entrepreneurs to align objectives and accelerate scale.

Wisconsin Super Angel Fund LP is a venture capital firm based in Milwaukee, Wisconsin, specializing in early-stage and startup investments. Founded in 2013, the firm is industry agnostic and focuses on companies based in Wisconsin, aiming to identify and capitalize on early exit opportunities. It typically invests between $0.25 million and $1 million in companies with pre-money valuations under $5 million, with a goal of exiting within three to five years of the initial investment. Additionally, the fund prefers to take two board seats in its portfolio companies, providing active mentorship and support to help them grow.

Venture Management is a venture capital firm based in Madison, Wisconsin, founded in 1994. It focuses on seed-stage and startup investments in Wisconsin, targeting technology and healthcare companies.

Founded in 2016, Winnebago Seed Fund is a venture capital firm based in Neenah, Wisconsin. It focuses on seed investments in startup companies primarily in the Fox Valley region and secondarily across Wisconsin. The fund aims to generate investor returns by partnering with talented entrepreneurs to accelerate business growth.

Founded in 2014, 4490 Ventures is a Madison-based venture capital firm focused on early-stage investments. It primarily invests in technology companies across sectors such as web3-enabled enterprise software, health tech, IoT, and SaaS, with a focus on the Midwest region.

Founded in 2015, HealthX Ventures is a venture capital firm based in Madison, Wisconsin. It focuses on investing in early-stage digital healthcare companies that aim to make healthcare safer, more efficient, and affordable through innovative, scalable solutions.

Idea Fund of La Crosse is a venture capital firm established in 2016 and located in La Crosse, Wisconsin. The firm focuses on investing in early-stage companies across a diverse array of sectors, including information technology, health information technology, data analytics, supply chain, agriculture, manufacturing, and financial services. By targeting a wide range of industries, the firm aims to support innovative businesses that have the potential for significant growth and impact.

30Ventures is a venture capital firm based in Madison, Wisconsin, established in 2017. The firm specializes in early-stage investments, particularly in Series A and B financing rounds, targeting high-potential companies within the healthcare and biotechnology sectors. Its focus areas include medical diagnostics, biotechnology tools, medical devices, and technologies related to industrial water and chemistry. 30Ventures is dedicated to fostering innovation in the Midwest, supporting startups that are poised to make significant impacts on human healthcare. The principals of the firm possess extensive experience in commercializing innovation, positioning them as key players in the regional entrepreneurial ecosystem.

Founded in 2010, American Family Ventures is a venture capital firm specializing in seed to series B investments. It focuses on companies developing technologies and business models relevant to the future of insurance, with an emphasis on FinTech, data analytics, IoT, cybersecurity, and home automation. The firm invests between $500k to $2m per round.

SymphonyAlpha Ventures, LLC is a Madison, Wisconsin-based venture capital firm that focuses on startup, early-stage, and angel investments, primarily within the healthcare IT and software-as-a-service sectors. As an operating subsidiary of Symphony Corporation, the firm aims to leverage nearly 20 years of expertise in healthcare technology to facilitate the development and market acceptance of innovative products. By utilizing a vast network of health systems and Fortune 500 companies, SymphonyAlpha Ventures supports entrepreneurs in bringing their ideas to market efficiently and effectively.

Bascom Ventures is a community of accredited UW-Madison alumni who pool capital to invest in UW-connected companies through a venture capital fund.

Inventure Capital is a Madison, Wisconsin-based venture capital firm founded in 2009 that invests in technology, biotech, and clean tech startups in the Midwest. The firm focuses on early-stage opportunities and also provides advisory services, including financial analysis and due diligence. Its portfolio spans healthcare technologies, digital authentication, and environmental tech, and it pursues a strategy that combines growth-focused technology investments with cash-flow-oriented real estate opportunities to balance risk and long-term value.

Calumet Venture Fund, founded in 2008 and based in Madison, Wisconsin, is a Midwest investment firm focused on the information technology sector. The firm specializes in early-stage investments, targeting companies in software, software-as-a-service, e-learning, and the arts and crafts industries. Through its strategic investments, Calumet Venture Fund aims to support the growth and development of innovative businesses within these dynamic sectors.

SHINE develops and deploys fusion-based technology to produce medical isotopes and neutron sources. Its processes generate molybdenum-99, a precursor to technetium-99m used in diagnostic imaging, and lutetium-177 for diagnostic and therapeutic use, along with iodine-131 and iodine-125 for thyroid treatment and brachytherapy, and xenon-133 for lung and brain imaging. The company’s systems also provide neutron sources for industrial imaging, radiation-effects testing, and fusion materials research. In addition to medical isotopes, SHINE aims to recycle nuclear waste and advance fusion power as a source of clean energy. The business serves health care and industrial customers worldwide. SHINE is based in Janesville, Wisconsin, with an office in Alkmaar, Netherlands.

Foley Ventures is the investment arm of the law firm Foley & Lardner, focusing on direct investments in early-stage startups and technology and life sciences companies, as well as fund-of-funds investments. It invests alongside venture funds and angel investors that support early-stage ventures and operates to collaborate with clients and client funds. Founded in 2011, Foley Ventures is based in Boston with additional offices in Madison, Wisconsin; Palo Alto, California; and Tampa, Florida. The firm backs a broad set of sectors, including software, services, internet, consumer, health care, biotech, medical devices, media, and other technology businesses.

Founded in 2000, Baird Venture Partners is a venture capital firm specializing in early to growth stage investments across various sectors including Technology & Services, Industrial Solutions, and Healthcare. The firm targets companies based in the United States, with a focus on Michigan, investing between $1 million and $12 million per company. They prefer to take a board seat in their portfolio companies.

Founded in 2015, Arenberg Holdings is a venture capital firm based in Milwaukee, Wisconsin. It invests in early-stage companies, with a focus on those located in the Midwest, particularly in the manufacturing sector.

Ben Franklin Technology Partners of Southeastern Pennsylvania is a technology-focused capital provider based in Philadelphia, founded in 1982 to advance the region's technology community. The organization funds and supports technology companies across Pennsylvania, especially in information technology, health, and physical sciences, investing substantial capital in early-stage and established ventures. It has invested over 170 million dollars in more than 1,750 regional technology companies and has launched university-industry partnerships to translate scientific discoveries into commercial products, while seeding regional initiatives that strengthen the entrepreneurial ecosystem and create jobs.

Alumni Ventures Group is a venture capital firm based in Manchester, New Hampshire, with offices across North America. It provides access to venture investing for individual accredited investors, particularly alumni networks, by offering diversified portfolios of venture opportunities and allowing members to invest alongside fellow alumni in ventures led by peers. The firm backs early-stage and later-stage opportunities across technology, consumer, healthcare, financial services, and other sectors, with a sector- and geography-agnostic approach. It typically invests between $10,000 and $3 million per deal and emphasizes the involvement of alumni connections and an institutional lead investor in opportunities. Alumni Ventures also offers focused funds to broaden participation, enabling accredited investors to access venture portfolios diversified by type, sector, stage, and geography. The model aims to democratize access to venture capital while maintaining rigorous selection standards through alumni networks.

GE Equity invests globally across various sectors, focusing on established companies with high growth potential. It takes minority ownership positions and offers growth capital, buy-out co-investments, secondary direct purchases, recapitalizations, and LP investments.

Established in 2018 and based in Madison, Wisconsin, Winnow Fund is a venture capital firm focusing on early-stage investments in Wisconsin-based companies.

Founded in 2016, TruStage Ventures is a venture capital arm of CUNA Mutual Group. It invests in early-stage financial technology, data analytics, education and protection, and digital channel sectors to advance financial solutions for consumers and credit unions.

CMFG Ventures is the venture capital arm of CUNA Mutual Holding Company. It focuses on seed, Series A or B, and other early to mid-stage investments, primarily in fintech, insurtech, credit union services, data and technology, mobile and online banking, consumer lending and asset protection, mobile channels, financial services, and insurance. The firm typically invests between $1 million and $5 million per company, and makes investments through balance sheet investments. Founded in 2016, CMFG Ventures is headquartered in Madison, Wisconsin, with an office in New York.

VC 414 is an early-stage venture capital firm based in Milwaukee, Wisconsin, established in 2022. It focuses on funding early‑stage B2B and B2B2C startups across the United States, prioritizing ventures led by women and other undercapitalized founders.

WVV Capital is a venture capital firm established in 2018 and based in Milwaukee, Wisconsin. The firm focuses on early-stage investments, targeting transformative innovations across several sectors, including healthcare, manufacturing, building technology, fintech, and information technology. WVV Capital is a joint venture that collaborates with notable partners such as Advocate Health, Foxconn, Johnson Controls, and Northwestern Mutual. As a Registered Investment Adviser, the firm aims to foster advancements that can significantly impact these industries in the United States.

WARF Ventures provides seed and growth funding to early-stage startups that are commercializing the University of Wisconsin-Madison and Morgridge Institute for Research technologies. Our strong connections to local, regional, and national venture capital communities mean WARF Ventures can help portfolio companies access additional support, reach early milestones, and attract follow-on investments.

Right Side Capital Management is a San Francisco-based venture capital firm that focuses on early-stage, pre-seed technology startups in underserved segments of the ecosystem. It invests in a high-volume, capital-efficient portfolio, typically funding rounds of 50,000 to 500,000 and making roughly 75 to 100 investments per year. The firm targets opportunities across the United States and internationally, including Canada, Israel, Australia, New Zealand, and Western Europe, prioritizing companies with scalable products and prudent capital use outside major metro hubs. Since its inception, it has built a broad portfolio across many states. It commits to a fast decision process, often delivering a yes or no within two weeks to help founders establish momentum.

Founded in 2015, FJ Labs is a New York-based venture capital firm focusing on stage-agnostic investments in marketplaces and consumer-facing startups. Their investment range varies from $50,000 to $5,000,000, typically at seed or series A stages.

MaSa Partners, founded in 2015, is a social impact venture that focuses on investing patient capital in early-stage, mission-driven companies. The firm is dedicated to supporting socially responsible businesses that aim to address contemporary challenges while achieving sustainable development. MaSa Partners provides both financial and human capital to these enterprises, reinforcing its commitment to creating positive social change without compromising on financial returns. Through its investments, MaSa Partners seeks to foster innovation and drive meaningful impact in various sectors.

CIBC Capital Partners is a Toronto-based investment firm specializing in direct, fund, and mezzanine investments. It provides subordinated debt and equity to mid- and late-stage private or public companies for growth financing, acquisitions, management buyouts, and recapitalizations. The firm prefers investments in later-stage companies undergoing financial restructurings, with a focus on sectors such as Industrials, Healthcare, Biotechnology, Financials, and Technology. It typically invests CAD10-20 million ($9.81-$19.61 million) per company, based primarily in Canada, Europe, and Australia.

Cleveland Avenue is a venture capital firm based in Chicago, founded in 2015. The firm makes investments across seed, early, later, and growth stages, with a focus on food and beverage companies, lifestyle consumer brands, AgTech, and technology businesses. It provides capital and strategic support to startups seeking to scale product offerings, expand into new markets, and build operational capabilities. As an investment adviser, Cleveland Avenue combines financial backing with hands-on guidance to help portfolio companies achieve long-term growth.

Baird Capital is a global investment firm that makes venture capital, growth equity, and private equity investments across regions worldwide. It partners with management teams and entrepreneurs to build growth‑oriented companies in sectors including healthcare, technology-enabled services, financial technology and services, industrial technology, and other B2B technology-driven industries. The firm seeks opportunities in lower middle‑market and middle‑market companies and aims to create value through active ownership and strategic support. With origins dating to 1989, Baird Capital maintains a global footprint spanning the United States, Europe and Asia through its affiliated platforms and regional teams.

OSF HealthCare is a not-for-profit Catholic health care system based in Peoria, Illinois, operating a multi-state network in Illinois and Michigan. It provides a wide range of services across hospitals, a medical group, primary and specialty care, behavioral health, and home care through affiliated entities. The system includes multiple acute care facilities and a physician network of more than 600 providers, supported by OSF Saint Francis organization and the OSF Healthcare Foundation. Guided by Catholic values such as justice, compassion, integrity, teamwork, and stewardship, it follows ethical principles in decision making and patient care. Established in 1877, it serves more than 2.5 million people in the communities it serves.

Serra Ventures is a venture capital firm based in Champaign, Illinois, that invests in technology companies across the United States and select international locations. The firm concentrates on early-stage and growth opportunities in information technology, deep technology, instrumentation, software as a service, devices, B2B, and agricultural technologies, with a focus on the Midwest and West Coast regions. Serra Ventures supports portfolio companies through strategic guidance, networks, and resources to help scale technology-enabled businesses.

Sand Hill Angels, established in 2000, is a prominent angel investor group based in Mountain View, California, comprising over 60 successful Silicon Valley technology professionals. The group is dedicated to supporting and growing startup companies, with a focus on seed-stage technology investments across North America. They typically invest between $300,000 to $500,000 in private companies, with a pre-money valuation of less than $5 million. Sand Hill Angels' investment preferences span various sectors, including clean technology, Internet startups, information sciences, and life sciences, with a particular interest in semiconductors, enterprise software, storage, communications, medical devices, diagnostics, and bioinformatics. The group collaborates openly with venture capital funds, other angel organizations, and the broader Bay Area ecosystem to foster the growth of technology startups.

Founded in 2006, Greycroft is a venture capital firm based in New York and Los Angeles. With over $1 billion under management, it focuses on early-stage investments in consumer internet, financial technology, healthcare, and enterprise software sectors across the United States. The firm leverages its extensive network of media and technology industry connections to help entrepreneurs gain visibility, build strategic relationships, and bring products to market.

Headline is a San Francisco-based venture capital firm founded in 1998 (formerly e.ventures). It maintains a global footprint with activity in seven cities and invests across geographies, leading rounds at every stage. The firm operates Early Stage Funds aligned with regional focus in the US, Europe, Asia, and Brazil to invest locally, and a Growth Fund based in San Francisco that participates from Series B onward. It backs companies across consumer, media, retail, financial services, healthcare, information technology, software-as-a-service, mobile, cybersecurity, e-commerce, artificial intelligence, advertising technology, and digital health. Notable portfolio companies include Sonos, The RealReal, Creditas, Sorare, Pismo, AppFolio, goPuff, Acorns, Farfetch, Segment, Bumble, and Yeahka. Headline is a registered investment adviser.

Trinity Capital is a lending firm that provides debt-based financing to growth-stage and venture-backed companies, including venture debt, revolving lines, senior and subordinated debt, and equipment financing. Headquartered in Phoenix, Arizona, it was founded in 2008 and collaborates with venture capital firms, technology banks, and portfolio companies to tailor financing solutions that help startups preserve equity while obtaining capital. The firm focuses on technology-driven and knowledge-based sectors, including healthcare, information technology, software as a service, financial services, consumer products, manufacturing, energy, cleantech, and nanotechnology, and supports growth, early-stage to later-stage ventures, buyouts, and acquisitions. Trinity Capital aims to partner with venture-backed startups seeking flexible capital to fuel growth, scale operations, or navigate strategic transactions.

Founded in 2014, Gaingels is a venture investment syndicate dedicated to supporting the LGBT+ community. It invests globally in companies led by LGBT+ founders or C-suite executives at all stages of growth, focusing on inclusivity and positive social change.

Service Provider Capital is a venture capital firm established in 2014 and based in Colorado. The firm focuses on early-stage investments, notably seed-stage opportunities, and participates as a co-investor in Series A rounds led by institutional venture funds. Its portfolio interests span a broad range of technology sectors, including artificial intelligence, machine learning, blockchain, cybersecurity, e-commerce, education technology, fintech, hardware, information technology, robotics, health, and cannabis.

Chisos Capital, established in 2020 and headquartered in Santa Monica, California, is a venture capital firm that specializes in providing financial support to high-potential athletes, entrepreneurs, and creators. The company writes checks ranging from $25,000 to $100,000 using Convertible Income Share Agreement terms, which allows it to invest in individuals with promising futures across various fields.