RUSNANO

Selecta Biosciences, Inc. is a clinical-stage biopharmaceutical company focused on developing nanoparticle immunomodulatory drugs for the treatment and prevention of human diseases. The company's proprietary platform utilizes advances in immunobiology and nanotechnology to create targeted immunomodulatory nanoparticles. Selecta's lead product, SEL-212, has successfully completed Phase II clinical trials for chronic refractory gout. Additionally, the company is advancing gene therapy candidates in preclinical development for rare metabolic disorders, including SEL-302 for methylmalonic acidemia and SEL-313 for ornithine transcarbamylase deficiency. Founded in 2007 and headquartered in Watertown, Massachusetts, Selecta Biosciences has established collaborations with various organizations, including Spark Therapeutics and the Massachusetts Institute of Technology, to enhance its research and development capabilities.

Selecta Biosciences, Inc. is a clinical-stage biopharmaceutical company focused on developing nanoparticle immunomodulatory drugs for the treatment and prevention of human diseases. The company's proprietary platform utilizes advances in immunobiology and nanotechnology to create targeted immunomodulatory nanoparticles. Selecta's lead product, SEL-212, has successfully completed Phase II clinical trials for chronic refractory gout. Additionally, the company is advancing gene therapy candidates in preclinical development for rare metabolic disorders, including SEL-302 for methylmalonic acidemia and SEL-313 for ornithine transcarbamylase deficiency. Founded in 2007 and headquartered in Watertown, Massachusetts, Selecta Biosciences has established collaborations with various organizations, including Spark Therapeutics and the Massachusetts Institute of Technology, to enhance its research and development capabilities.

DSK Grad LLC is a high-tech design and manufacturing company based in Naro-Fominsk, Russia, specializing in prefabricated units for residential construction. Founded in 2014, it stands out as the first national-scale manufacturer in this sector to emerge in the last 30 years, positioning itself uniquely within the Russian construction industry. DSK Grad leverages advanced international technologies and innovative developments from RUSNANO, utilizing materials such as paints, fillers, and concrete additives sourced from various industry partners. The company's focus is on demonstrating that the integration of modern technologies in construction can enhance product quality while simultaneously lowering costs, achieved through efficiencies in transportation and reduced maintenance of prefabricated buildings. DSK Grad aims to set new industry standards by offering solutions that meet the demands of complex construction projects through the use of composite materials and nanotechnology.

OCSiAl, headquartered in Luxembourg, is the world's largest manufacturer of graphene nanotubes, also known as single wall carbon nanotubes. The company employs over 420 experts across various countries, including the United States, China, India, Japan, South Korea, and several European nations. OCSiAl's primary product, graphene nanotubes, is recognized for its remarkable properties and has become an industrial standard across multiple sectors, including transportation and aerospace. These nanotubes are essential components in advanced technologies such as silicon-anode batteries, which are anticipated to be widely adopted by leading electric vehicle manufacturers in the coming decade. OCSiAl commands 97% of the global production capacity for graphene nanotubes and is experiencing rapid growth, with a valuation that reached approximately $2 billion following a capital raising round in 2021. The company's offerings enhance the performance of elastomers, composites, plastics, coatings, and batteries, contributing to energy efficiency, durability, safety, and reductions in CO2 emissions.

NeoPhotonics is a technology company specializing in the development, manufacture, and sale of optical components and subsystems used in high-speed digital communications networks. The company offers a comprehensive range of active and passive optical products tailored for various market segments, including fiber-to-the-home (FTTH), data communications, storage area networks, and both metro and long-haul networks. Its product lineup includes transceivers, integrated splitters, multiplexers, and advanced optical modules, all designed to support a wide array of data rates and applications. Notably, NeoPhotonics is recognized for its innovative silica Planar Lightwave Circuit (PLC) technology, which plays a crucial role in modern optical networks. Additionally, the company produces MEMS-based Variable Optical Attenuators and Dynamic Channel Equalizers, enhancing the performance and efficiency of communication systems.

Beneq is a company that specializes in the development and manufacturing of equipment for thin film atomic layer deposition (ALD) and aerosol coatings. It provides advanced production and research tools designed for nano-scale thin film coatings, primarily targeting the semiconductor industry and other research and development sectors. Beneq's technology aims to enhance product longevity and performance, particularly through its thin film electroluminescent (TFEL) displays. By focusing on innovative ALD technology, Beneq supports various industrial applications, contributing to advancements in the field of nanotechnology.

BIND Therapeutics is a clinical-stage nanomedicine platform company focused on developing innovative targeted and programmable therapeutics known as Accurins. These specialized drug delivery systems are engineered with distinct physical and chemical properties to effectively target specific cells or tissues, concentrating therapeutic agents at the disease site to improve treatment efficacy while reducing adverse effects on healthy tissues. BIND's primary focus is on oncology, with its lead drug candidate, BIND-014, currently undergoing Phase 2 clinical trials for non-small cell lung cancer and metastatic castrate-resistant prostate cancer. The company also collaborates with leading biopharmaceutical firms, such as Amgen, Pfizer, and AstraZeneca, to create Accurins utilizing their therapeutic payloads. Through its medicinal nanoengineering platform, BIND Therapeutics aims to advance its own pipeline and forge strategic partnerships in the field of cancer treatment.

Selecta Biosciences, Inc. is a clinical-stage biopharmaceutical company focused on developing nanoparticle immunomodulatory drugs for the treatment and prevention of human diseases. The company's proprietary platform utilizes advances in immunobiology and nanotechnology to create targeted immunomodulatory nanoparticles. Selecta's lead product, SEL-212, has successfully completed Phase II clinical trials for chronic refractory gout. Additionally, the company is advancing gene therapy candidates in preclinical development for rare metabolic disorders, including SEL-302 for methylmalonic acidemia and SEL-313 for ornithine transcarbamylase deficiency. Founded in 2007 and headquartered in Watertown, Massachusetts, Selecta Biosciences has established collaborations with various organizations, including Spark Therapeutics and the Massachusetts Institute of Technology, to enhance its research and development capabilities.

AQUANOVA is a Russian industrial manufacturer specializing in the production of NovaSOL® solubilizates, which are nanoparticle-based additives. Utilizing advanced technology from Germany, AQUANOVA encapsulates active organic substances within micelles approximately 30 nanometers in diameter. This innovative approach enhances the effectiveness of natural components while optimizing economic performance by significantly reducing the quantity of costly natural substances required in final products, such as food ingredients, by three to five times without compromising functionality. The company's product range includes complex additives for the food industry and active substances for the cosmetic and pharmaceutical sectors, which incorporate antioxidants, vitamin complexes, preservatives, nutrients, natural dyes, and oils. AQUANOVA operates a fully automated and high-tech production facility to ensure the quality and consistency of its offerings.

ICM Glass Kaluga is a manufacturing enterprise specializing in the production of foam glass crushed stone, a novel material in Russia. Utilizing nanotechnology to process unsorted cullet, the company creates foam glass with distinctive properties such as wide temperature application range, water and vapor impermeability, non-flammability, size stability, high strength, resistance to aggressive media, rodents, and insects. These unique features make foam glass an ideal universal particulate for thermal insulation in construction and industrial engineering projects.

Novomet is a manufacturer of advanced artificial lift equipment and electrical submersible pumping systems tailored for the oilfield services and energy industries. The company specializes in high-capacity oil production equipment, incorporating innovative nanostructured protective coatings to enhance durability and efficiency. Novomet's submersible pumps are recognized for their reliability and energy efficiency, particularly in challenging oil production environments. With a significant market share of 25% in Russia and 3% internationally, the company focuses on creating equipment suited for complex operational conditions. In addition to manufacturing, Novomet is developing a global service network that provides comprehensive maintenance services for electric centrifugal pumps, including the selection of optimal units for specific wells, reservoir pressure maintenance systems, and water injection systems. This holistic approach aims to address the challenges of declining oil recovery and improve operational efficiency for its clients.

Selecta Biosciences, Inc. is a clinical-stage biopharmaceutical company focused on developing nanoparticle immunomodulatory drugs for the treatment and prevention of human diseases. The company's proprietary platform utilizes advances in immunobiology and nanotechnology to create targeted immunomodulatory nanoparticles. Selecta's lead product, SEL-212, has successfully completed Phase II clinical trials for chronic refractory gout. Additionally, the company is advancing gene therapy candidates in preclinical development for rare metabolic disorders, including SEL-302 for methylmalonic acidemia and SEL-313 for ornithine transcarbamylase deficiency. Founded in 2007 and headquartered in Watertown, Massachusetts, Selecta Biosciences has established collaborations with various organizations, including Spark Therapeutics and the Massachusetts Institute of Technology, to enhance its research and development capabilities.

Nearmedic is a pharmaceutical company focused on the production and development of antiviral medications, particularly emphasizing its flagship product, Kagocel. This antiviral drug, available over the counter, leverages a unique formulation that combines a plant-based molecule with a nanosized polymer carrier, enhancing its pharmacological activity while minimizing toxicity. Nearmedic is in the process of establishing a new GMP-compliant manufacturing facility, which will allow it to transition away from rented production spaces and significantly increase its manufacturing capabilities. This expansion aims to strengthen its market position in Russia and the CIS. In addition to Kagocel, Nearmedic is involved in the full-cycle production of nanomedicines, as well as the development of diagnostic kits and laboratory equipment, contributing to advancements in patient health and treatment options for various viral infections, including flu and herpes.

Thermointech specializes in the development and production of thermoelectric systems and devices, utilizing innovative technologies for thermoelectric material synthesis. The company offers both ready-made, efficient, and cost-effective solutions, as well as opportunities for clients to create exclusive concepts tailored to their specific needs. By focusing on the full automation of the production cycle, Thermointech ensures high-quality products and services in the field of nanotechnology, particularly concerning thermoelectric materials and coatings.

Close Joint-Stock Company NEVZ-CERAMICS specializes in the development and production of nanostructured ceramics for various industries, including power, radio electronics, machine engineering, and petrochemicals. The company offers a range of products, such as ceramic substrates, metalized alumina oxide and alumina nitride ceramics, insulators, and bioceramics tailored for medical applications like endoprostheses and implants. NEVZ-CERAMICS aims to expand the applications of ceramics, particularly in the medical field, through the creation of biocompatible nanoceramics for traumatology and orthopedics. The company is equipped with advanced production facilities, research laboratories, and transportation infrastructure to support its operations. Founded in 2011 and based in Novosibirsk, Russian Federation, NEVZ-CERAMICS serves a diverse clientele across several sectors, including atomic power and chemical industries.

Advenira Enterprises, Inc., headquartered in Sunnyvale, California, specializes in manufacturing and marketing advanced nano components. The company's core technology, Solution Derived Nanocomposite (SDN), enables low-cost, high-throughput deposition of multifunctional coatings. These coatings, offered as hardware, precursors, and processing solutions, cater to a wide range of industries, including energy-efficient glass, solar cells, flat panel displays, semiconductors, and food packaging. Advenira's products aim to enhance product longevity, reduce costs, and minimize environmental impact.

Nanoelectro is a manufacturer specializing in nanostructured electrical cables designed for electrotechnical conductors. The company's unique production technology involves melting and assembling bimetallic materials, which are then deformed to introduce niobic fibers into the copper matrix of the wire. These fibers, measuring 6 nm to 10 nm thick, enhance the mechanical durability of the cable to between 1,000 MPa and 1,200 MPa. The resulting composite wire maintains high electrical conductivity, ranging from 65% to 85% of ultrapure copper. Nanoelectro's cables are designed for applications requiring both strength and efficient electrical performance. The company has already garnered significant interest from various Russian and international companies seeking to purchase this advanced superwire.

Profotech specializes in the production of advanced fiber-optic systems designed for energy measurement and power grid protection. The company leverages innovative technology by incorporating nanofibers into its fiber-optic current and voltage sensors, enhancing their performance and efficiency. These nanofibers, characterized by nanosized quartz ribs encased in a load-bearing quartz sheath, enable Profotech to offer superior solutions tailored for the power industry and other energy-intensive sectors. By focusing on domestic production, Profotech aims to replace imported products with locally manufactured alternatives that exhibit improved consumer properties.

Zao Nir is a full-cycle production of instruments with nanostructured PVD coating using a deposition technology developed at Kurchatov Institute Researchers at the Kurchatov Institute developed the technology used in this project—application of nanostructured coatings to metal-cutting instruments. The coatings increase wear resistance of the tools by 2.5 times, decreasing the frequency of replacement and lowering overall tool costs.

Microbor Composite Co. specializes in the development and manufacturing of advanced composite materials, specifically Cubic Boron Nitride (CBN) and Nano Cubic Boron Nitride (NCBN). As the first global producer to offer commercial tools made from NCBN, the company produces cutting tools that are designed for precision and quality in machining applications. These tools are available in various geometries and sizes, including interchangeable soldered and monolithic plates for turning and milling operations. By leveraging the superior strength of NCBN, which outperforms synthetic diamond in both temperature and wear resistance, Microbor Composite Co. aims to enhance the accuracy and efficiency of industrial cutting processes.

Nanotech-Dubna is a developer of advanced nanomaterials, specifically specializing in colloidal quantum dots, which are nanocrystalline semiconductor materials that display remarkable photostability and variable fluorescence across a wide wavelength range. The company's innovative products cater to diverse industrial markets, including security applications, next-generation LED lighting, biomedical markers, and electronic devices. By harnessing the unique properties of quantum dots, Nanotech-Dubna aims to impact various fields such as biomedicine, computing, telecommunications, and optoelectronic devices. Their commitment to advancing nanotechnology positions them at the forefront of emerging applications that leverage the capabilities of nanoscale materials.

Membranium is a Russian company specializing in the production of nanostructured membrane flat-sheets and elements designed for advanced filtration processes, including reverse osmosis, nanofiltration, and ultrafiltration. The company focuses on enhancing the efficiency of pure water production through innovative membrane technologies. Its products feature specialized pores that facilitate the delivery of healthy and safe drinking water while minimizing the costs associated with obtaining ultraclean, salt-free water free from harmful microbes. With a commitment to advancing national membrane science and technology, Membranium aims to establish itself as a leader in the global membrane manufacturing industry.

MetaClay specializes in the production of advanced modified layered nanosilicates, masterbatches, and polymer nanocomposites for industrial applications. The company's technology is based on innovative research from prominent Russian scientific institutions, including the A. V. Topchiev Institute of Petrochemical Synthesis and Lomonosov Moscow State University. MetaClay's products enhance the longevity and durability of metal pipes, extending their service life up to 60-80 years, and are effective in extreme temperature conditions ranging from -60ºC to +80ºC. Additionally, these materials reduce gas permeability and protect against damage from solar radiation. The effectiveness of MetaClay's coatings for large-diameter pipes has been validated by Gazprom VNIIGAZ, and they are utilized in the production of pipes for major projects like the Power of Siberia Gas Pipeline. The company aims to secure certification for its nano-coated pipes in projects by Transneft and Rosneft. With a focus on technological advantages and cost efficiency, MetaClay is positioned to compete effectively with foreign manufacturers in the Russian market, particularly in offering more economical alternatives to traditional three-layer insulation.

Advanced Technologies Center manufactures analytical instruments for research in materials science, biology, and medicine. Production of high-precision sensors for analyses of chemical and biological substances. dvanced Technologies Center manufactures the FemtoScan series of scanning probe microscopes—precision instruments that use the mechanical movement of a probe (cantilever) to study the surface of an object. The microscopes are precise to about one nanometer. ATC also produces atomic scales that can register the presence of particles of various substances at the level of individual atoms. One promising application of these scales is as quick-response biosensors. The company has established an R&D center where it will conduct research to perfect technology, carry out engineering development, and test prototypes and models. The center will supply software to work in instrument-managing and image-processing modes. The scanning probe microscopes that ATC produces are capable of more than 50 sophisticated research regimes—contact atomic force microscopy, resonance atomic force microscopy, scanning frictional microscopy, scanning resistance microscopy, scanning tunneling microscopy, electrostatic microscopy, magnetic force microscopy, force curve analysis, and nanolithography among them. Combining compact size with powerful software packages, ATC instruments can be accessed through the Internet with open architecture.

Plakart is a company that provides industrial customers with advanced solutions for applying multipurpose nanostructured coatings, which include thermal-barrier, wear-resistant, and corrosion-resistant formulations. Through a network of service centers, Plakart specializes in protecting critical infrastructure such as drilling platforms, bridges, and steel structures from the damaging effects of corrosion and wear. The company utilizes robotic equipment and operates metallurgical laboratories to ensure strict quality control, enabling the production of coatings with precise properties such as hardness, porosity, and adhesion. In addition to its coating solutions, Plakart offers equipment related to thermal spraying, cladding, and spare parts, further enhancing its capabilities in anticorrosive and wear-proof applications.

Uralplastic-N is using know-how in three related areas: production of nanocomposites from clay and ceramics, introduction of nanocomposite additives to polymer packaging material, and manufacturing of modified flexible films with improved qualities.

RUSCHEMBIO is a provider of laboratory warehousing and delivery services focused on the needs of the Russian nanoindustry. The company offers a wide range of products, including biochemical reagents, medical and veterinary equipment, diagnostic kits, and nanomaterials. Through an extensive system of express deliveries, RUSCHEMBIO ensures that scientists and professionals have timely access to essential supplies. The company has established a diverse assortment of reagents and has become one of the first in its sector to achieve profitability. RUSCHEMBIO plans to expand its operations by opening new branches and warehouses in Novosibirsk, Nizhny Novgorod, and Stavropol. Additionally, it aims to develop its own brand and catalog to promote products from Russian manufacturers, while also including offerings from independent nanoproducers to enhance its product assortment.

NTpharma provides GMP production of nanovaccines and biopharmaceuticals containing carbohydrate binders. The project provides for building a facility for production of vaccines and pharmaceuticals in the municipal area of Pereslavl’-Zalessky, 150 kilometers (85 miles) northeast of Moscow. The project aims at production of new generation vaccines, including a polyvalent human flu vaccine, and pharmaceuticals for detoxification in oncological therapy and for treatment of amyotrophic lateral sclerosis (ALS/Lou Gehrig’s disease). NTpharma’s technology allows to reduce by half the time required for culturing and production of the vaccine. This advantage is vital when dealing with vaccines for pandemic flu strains spreading rapidly all over the world.

Indec is a manufacturer specializing in high-tech electrochemical machines used for precision machining of metal and alloy parts. The company develops advanced machines and technologies that utilize a one-component electrolyte, allowing for the processing and manufacturing of components from a diverse array of materials, including various metals, alloys, metal-ceramics, and nanostructured substances. Indec's innovative solutions enable clients to achieve optimal precision in electrochemical machining, catering to the needs of industries requiring high accuracy in part fabrication.

NPC Springs LLC, a design company under the State Corporation Rosnanotekhnologii, specializes in the production of heavy-duty nanostructured springs. These springs are characterized by their enhanced strength, durability, and geometric accuracy, making them suitable for various industrial applications. The company employs advanced technology that focuses on the controlled pattering of the material's nanosubstructure, ensuring the high performance of its products. Additionally, NPC Springs has established a unified environment for automatic accounting, analysis, and business process management, which streamlines its operations and enhances efficiency in manufacturing.