Innovation Works

Advanced Optronics specializes in the design and manufacture of implantable sensors aimed at enhancing intraoperative monitoring during surgical procedures. The company focuses on developing flexible, biocompatible sensor systems that facilitate less traumatic insertions, thereby minimizing trauma and protecting residual hearing during cochlear implant surgeries. By integrating advanced flexible micro-electromechanical system sensors with cochlear implants, Advanced Optronics enables surgeons to achieve improved surgical outcomes and enhance patient safety across various medical applications.

Parcel Health is dedicated to revolutionizing medication packaging with its innovative, sustainable solutions. The company has created the world's first paper-based prescription bottle, which is fully brandable and compostable. This eco-friendly packaging not only addresses environmental concerns but also enhances temperature control and logistical safety during the shipping of medications, thereby minimizing in-transit damage and improving customer satisfaction. Designed to be both child-resistant and elderly-friendly, Parcel Health's products aim to streamline pharmacy workflows and reduce medication errors. By offering these sustainable alternatives, the company supports pharmacies and pharmaceutical companies in achieving their carbon neutrality goals while providing a reliable and efficient packaging solution.

Rimsys is a leading provider of Regulatory Information Management (RIM) software specifically designed for medical technology companies. The software is tailored for regulatory affairs professionals, enabling them to digitize and automate compliance processes to meet evolving global regulations. Rimsys offers a comprehensive solution that manages global Unique Device Identification (UDI) requirements and facilitates the navigation of essential regulatory components, including product registration, standards management, and regulatory intelligence. By actively tracking product registrations and monitoring relevant technical files and standards, Rimsys simplifies regulatory management for clients, transforming their operations into a more organized and efficient system for teams and international partners.

Forest Devices, Inc. is a medical device company based in Pittsburgh, Pennsylvania, with an additional office in Canada. Founded in 2014, the company specializes in developing innovative solutions for stroke detection. Its flagship product, AlphaStroke, is a portable and non-invasive stroke screening device that assists medical personnel in identifying early signs of both ischemic and hemorrhagic strokes. By enabling pre-hospital providers to accurately assess patients, AlphaStroke facilitates timely triage and enhances decision-making in critical care scenarios, ultimately aiming to reduce treatment delays and improve patient outcomes.

Revitalize Energy is a consumer-focused company that develops eye drops aimed at alleviating fatigue associated with prolonged screen use. The product features a patented blend of stimulants and amino acids designed to moisturize the eyes and provide instant relief from tiredness. By applying just 1-2 drops, users experience a refreshing effect that helps combat the discomfort caused by digital devices, allowing them to feel revitalized and more alert. The company's innovative approach addresses a growing concern in today's technology-driven environment, where eye strain and fatigue have become increasingly common.

Hummingbird Systems provides On demand aerial mapping and data analysis of construction sites and agriculture using drones.

BlastPoint is a developer of a predictive AI-powered platform that offers big data solutions to help companies optimize revenue growth and enhance customer engagement. By providing tools to discover, target, and engage humans within their data, BlastPoint enables businesses across various sectors—such as energy, financial services, automotive, and nonprofit organizations—to generate immediate insights into customer engagement challenges. The platform equips clients to identify trends and unlock critical information relevant to specific territories, ultimately empowering them to find, reach, and satisfy customers throughout their lifetime.

Sitewiz is a technology company that specializes in digital experience optimization. It employs generative AI and data-driven analytics to enhance website conversion rates. The company's platform offers AI-driven insights, prioritizing actionable recommendations to improve customer engagement and boost conversion rates. This enables businesses to efficiently focus on the most impactful actions, thereby improving website performance.

CapSen Robotics, Inc. specializes in advanced 3D computer vision systems that empower computers and robots to effectively interpret and navigate the cluttered physical world. Founded in 2016 and based in Pittsburgh, Pennsylvania, the company develops a range of solutions including cluttered object detection, scanning for both large and small objects, and object tracking. These technologies are applicable across various sectors such as factory automation, vehicle scanning and measuring, and retail inventory management. CapSen Robotics leverages cutting-edge research from MIT to enhance the capabilities of robotic systems, enabling them to operate in less structured environments like hospitals, warehouses, and homes. The company is currently collaborating with system integrators and robotics firms on applications that involve robotic picking and has partnered with a leading government contractor for warehouse applications. Their innovations are poised to have a significant impact across consumer, industrial, and defense markets.

Gridwise, Inc. is a technology company based in Pittsburgh, Pennsylvania, that specializes in developing a mobile application designed for rideshare and delivery drivers. Founded in 2016, Gridwise offers a comprehensive platform that assists gig economy drivers in maximizing their earnings and enhancing their business operations. The application provides real-time insights on passenger demand, traffic, and weather, as well as alerts for nearby opportunities. Additionally, it features tools for tracking mileage, calculating tax deductions, and generating detailed tax reports. With its focus on performance tracking and earnings analysis, Gridwise empowers hundreds of thousands of drivers across the United States to effectively manage their gig work.

FoodSocial is a digital recipe creator and cooking platform focused on promoting healthy cooking. The platform enables creators and brands to share their recipes and food-related content, facilitating a space for users to discover, meal plan, and shop for their favorite recipes. By doing so, FoodSocial inspires individuals to engage with nutritious cooking while supporting the creators they admire. The service aims to enhance the culinary experience by making it easier for users to access and enjoy diverse recipes tailored to their dietary preferences.

Peoples Energy Analytics specializes in providing a comprehensive, data-driven platform aimed at utility customer analysis and bill assistance. The company focuses on identifying customers at risk of defaulting on their energy bills, allowing utility organizations to proactively connect these individuals with financial support long before they miss payments. By offering a complete suite of services that includes strategy design, data analysis, and marketing outreach, Peoples Energy Analytics helps utility companies reduce unpaid bills and enhance revenue recovery. Their scalable and cost-effective solutions are designed to modernize customer engagement, ultimately improving the overall experience for utility customers.

iTruckr is a technology company specializing in AI-powered communication and logistics solutions for the trucking industry. It offers a cross-platform solution that automates messaging and real-time tracking, connecting dispatchers, drivers, brokers, and warehouses via SMS, WhatsApp, email, and phone calls. Designed for mid-sized fleets, iTruckr eliminates the need for additional apps or complex onboarding, ensuring seamless communication and reducing operational delays. By automating core processes, it optimizes operations, reduces human errors, and enhances profitability, allowing trucking companies to scale without hiring additional staff. The platform provides 24/7 messaging and automation, leading to faster response times, improved driver satisfaction, and fewer delivery delays.

HeadStrait Labs is a medical equipment manufacturing company focused on developing innovative devices for head and neck immobilization in pre-hospital care. The firm aims to enhance patient outcomes during ambulance transportation by providing healthcare professionals with effective solutions to stabilize patients’ head and neck during critical situations. Through its specialized products, HeadStrait Labs addresses the urgent need for reliable immobilization techniques, thereby contributing to improved safety and care in emergency medical settings.

Journey Robotics is an aerospace engineering firm focused on developing automation tools designed to enhance the safety and efficiency of airline operations. The company aims to streamline processes related to loading, unloading, and handling passenger cargo, thereby improving overall operational efficacy within the aviation sector. Currently, Journey Robotics is operating in stealth mode, indicating a focus on research and development before a public launch of its innovative solutions.

Humotech is a developer of a wearable robotics platform focused on advancing research and development in prosthetics, orthotics, and exoskeletons. The company's flagship offering, the Caplex system, allows researchers to emulate real-world physical characteristics of their concepts, facilitating exploration, experimentation, and innovation with reduced risk and shorter development timelines. This programmable and high-performance platform provides customizable and expandable hardware and software, enabling users to rapidly develop, test, and evaluate wearable assistive technology ideas with human users prior to physical prototyping.

ForSight Assistive Devices is an Health Tech firm offering sensory system for effective mobility of disabled people.

Reclamation Factory is an Environmental Services offering firm making automated and transparent plastics recycling equipment.

Ocugenix is a therapeutics company dedicated to developing cancer immunotherapy drugs aimed at treating ocular diseases. The company focuses on creating small molecule immunotherapy drugs that target drug-resistant bacteria, which are intended to help manage complications related to cancer treatments in the eye. By addressing issues such as fibrosis and angiogenesis, Ocugenix seeks to enhance the efficacy of cancer-related eye treatments, thereby improving patient outcomes in the field of ocular oncology.

Plexision develops cellular biomarkers for personalized diagnosis and drug development in solid organ transplantation, and immunological disorders. Plexision's first patented product, the PleximmuneTM assay, predicts the risk of transplant rejection. The test is based on patent-pending technology to measure antigen-specific white blood cells. Testing services for transplant recipients and drug developers are provided at Plexision’s CLIA-certified, central laboratory in Pittsburgh. Plexision currently offers cell-based testing for personalized assessment of rejection risk after solid organ transplantation The Pleximmune blood test is the first such test offered for children with liver or intestine transplantation.

Honeycomb Credit, Inc. operates a peer-to-peer lending platform that connects small business owners with individual investors seeking to fund those businesses. Founded in 2017 and based in Pittsburgh, Pennsylvania, the company allows businesses to secure loans from their own customers and community members, facilitating debt crowdfunding. This innovative approach enables small businesses to obtain necessary capital without relinquishing equity, thus supporting their growth while providing a unique investment opportunity for lenders. By bridging the gap between traditional funding sources and community support, Honeycomb Credit enhances access to financial resources for small enterprises.

Belong For Me is a SAAS firm offering personalized approach to employee through their product CoExperiences.

SignatureDx is a biotechnology company that develops and operates a bioanalytical platform. This platform is designed to detect and monitor complex human diseases in their early, silent stages. The company focuses on non-invasive diagnostic testing, aiming to predict and treat diseases before they cause significant organ damage. By specializing in novel methods, SignatureDx enables individuals to receive timely and successful treatment, thereby improving health outcomes.

Thiopoly is a developer of pharmacy software focused on enhancing medication management. The company’s platform utilizes advanced technologies, including Internet of Things (IoT) sensing, artificial intelligence, cloud computing, and mobile applications, to create user-friendly and scalable systems. By integrating these innovations, Thiopoly aims to improve the overall healthcare experience for pharmacy companies, making medication management more agile, intuitive, equitable, and efficient.

Toyz Electronics is a Pennsylvania-based company that specializes in developing innovative technology solutions for the education sector. The company focuses on a gamified learning platform aimed at empowering students to acquire skills in STEAM (science, technology, engineering, art, and math), as well as entrepreneurship and storytelling. Through a unique approach that incorporates a superhero rap concept, Toyz Electronics offers a project-based curriculum that is culturally relevant and responsive. The platform utilizes elements such as hip-hop culture, music, gaming, three-dimensional models, comics, and design to engage students effectively. This comprehensive approach enables learners to develop a diverse range of technical and soft skills while creating their own superhero avatars and sharing personal narratives.

Good Company Technologies is currently operating in stealth mode.

PittMoss LLC is a manufacturer based in Ambridge, Pennsylvania, specializing in sustainable gardening solutions. The company produces PittMoss, a peat-free potting mixture made from organic additives and recycled paper fibers, which are designed to serve both commercial greenhouses and nurseries, as well as home gardeners across the United States. PittMoss is developed as a substitute for traditional sphagnum peat moss, providing an environmentally friendly alternative that helps reduce landfill waste. Additionally, the company offers PittMoss Prime, a versatile soil amendment that can be combined with compost, existing soil blends, or native soil to enhance plant growth. Founded in 1994, PittMoss emphasizes innovation through its research into recycling paper materials for horticultural use.

Wack is a software development company that specializes in creating tools to enhance security and improve the developer experience in web development. Their primary product, Agentic, is designed to help teams identify and fix production bugs before they affect end-users, enabling confident and scalable software shipping.

Lead-In Record Co. is a music technology firm that specializes in on-demand record manufacturing services tailored for independent artists. By utilizing advanced technologies such as 3D printing and computer numerical control (CNC), the company streamlines the record production process, allowing artists to produce vinyl records quickly and efficiently. This innovative approach enables musicians to meet their specific needs without the constraints of traditional manufacturing methods, making it easier for them to distribute their music in a physical format.

Sensible Photonics is a company focused on developing innovative fiber optic sensing technologies aimed at enhancing the monitoring of grid equipment and energy storage solutions. The company manufactures noninvasive sensors that monitor transformers, batteries, and other electrical assets, providing real-time temperature readings and predictive analytics. These sensors enable the proactive identification of potential failures, including thermal runaway, allowing for timely maintenance and improved reliability. By offering insights into the health of critical electrical equipment, Sensible Photonics enhances operational efficiency, extends equipment lifespan, and contributes to financial savings and safety for its clients.

Sensi Fit is a manufacturer specializing in athletic equipment, primarily developing fitness testing sensors. These sensors are designed to facilitate athletic testing for high-performance athletes, providing real-time quantitative data, biomechanics feedback, and training guidance. This enables athletes to enhance their performance without the need for wearables.

Workers First is a research and design company founded in 2016 and headquartered in Pittsburgh, Pennsylvania. The company specializes in developing innovative polymer materials that enhance worker protection, particularly in hazardous environments. Its patented polymer technology is designed to neutralize acids on contact, making it suitable for use in personal protective equipment and acid-proof linings. This advancement enables workers to perform their jobs safely and effectively in situations where they are exposed to corrosive substances, thereby improving overall safety and productivity in the workplace.

CleverApply is an educational administration platform founded in 2020 and headquartered in Ohio, United States. The company specializes in matching students with universities and educational agents by utilizing artificial intelligence and blockchain technology. Its platform enables users to identify suitable universities based on their desired programs and individual needs. Additionally, CleverApply facilitates connections between students and schools, assists in document review, and provides interview preparation resources, streamlining the application process for prospective students.

PredxBio is a computational pathology company that specializes in the development of artificial intelligence tools for analyzing whole slide image pathology samples through spatial analytics. The company focuses on enhancing the capabilities of clinicians and researchers by providing tools that accelerate drug discovery, optimize clinical trials, and improve companion diagnostics. PredxBio's platform employs AI and machine learning to automatically recognize and classify regions of interest in H&E-stained and immunohistochemistry slides. This technology aids pathologists and biopharma companies in making informed clinical decisions and developing personalized therapeutic strategies. By leveraging personalized spatial intelligence, PredxBio aims to streamline clinical workflows and advance the overall efficiency of the drug development process.

Subtl Beauty, Inc. is a cosmetics brand founded in 2018 and based in Pittsburgh, Pennsylvania. The company specializes in the production of stackable makeup products designed for contemporary women seeking convenience and flexibility in their beauty routines. Its unique packaging allows for modular, customizable stacks that can easily fit in a gym bag, purse, or back pocket, making them ideal for on-the-go lifestyles. Subtl Beauty's product offerings are crafted for efficiency, easy application, and long-lasting wear, aligning with the values of conscious consumers by being clean, vegan, cruelty-free, paraben-free, and fragrance-free. The company's online sales platform further enhances accessibility for customers seeking innovative, travel-friendly makeup solutions.

ExchangeLodge LLC is a financial technology company that specializes in business process automation and data integration for private capital firms. Founded in 2015 and based in Pittsburgh, Pennsylvania, the company offers a platform designed to streamline data management and enhance operational efficiency. This platform provides users with a comprehensive playbook of essential workflows, enterprise data connectors, and high-quality reports suitable for boardroom presentations. By automating manual data processes and integrating existing systems, ExchangeLodge mitigates risks associated with data inaccuracies and key personnel dependencies. The platform enables teams to design and manage reporting, track tasks and their progress, and generate actionable insights for decision-making, ultimately improving data quality and supporting compliance with investor and regulatory requirements.

BioHybrid Solutions is a biotechnology company that specializes in developing advanced nanoarmored protein-polymer conjugates. The company focuses on tailoring the activity and stability of proteins and enzymes for various applications. Utilizing atom transfer radical polymerization chemistry, BioHybrid Solutions precisely grows polymers from the surface of proteins, enhancing their functionality. Through its research and development efforts, the company aims to provide innovative alternatives for therapeutics and protein engineering, ultimately contributing to advancements in medical treatments.

Ecotone Renewables is focused on enhancing sustainable food and agricultural systems outside of large industrial frameworks. The company aims to empower communities to develop through sustainable food practices by providing innovative solutions for waste management. One of their key innovations, the "Seahorse," revolutionizes food and plant waste disposal by converting organic waste into renewable energy and nutrient-rich fertilizers through anaerobic digestion. By integrating patent-pending technology, Ecotone effectively removes contaminants such as plastic, metal, and glass from waste, creating efficient waste systems that serve various sectors, including grocery stores, college dorms, hotels, and restaurants. The company’s mission is to eliminate food waste and promote sustainability by transforming discarded food and energy into valuable nutrients, thereby closing the food loop and fostering sustainable communities.

Phlux Technologies, founded in 2020 and based in Pittsburgh, Pennsylvania, specializes in developing innovative 3D sensor technology for industrial robotics and automation. The company's core products are programmable 3D sensors that enhance safety and efficiency by enabling robots to navigate effectively, protecting workers from hazards, and detecting obstacles. Phlux Technologies' proprietary optical sensing technology, combined with artificial intelligence and computer vision, creates digital safety zones around machinery, optimizing floor space usage and reducing setup times.

Ilant Health is a healthcare provider specializing in obesity management and cardiometabolic healthcare services. The company focuses on delivering effective obesity treatment through innovative analytics powered by unstructured machine learning. This approach has yielded significant insights into reducing total healthcare costs and enhancing return on investment for obesity treatment. By prioritizing value-based care, Ilant Health enables its clients to achieve better health outcomes while also managing costs more effectively.

Testa-Seat is a company that specializes in developing affordable, adaptable seating solutions for children with special needs. The firm offers creatively designed, 3D-printed seating devices that enhance mobility and independence for individuals with disabilities. By providing body-contouring therapeutic positioning equipment, Testa-Seat ensures optimal support for users with mild to moderate body control. Their products are aimed at reducing the risks associated with improper seating during critical developmental stages, thereby improving comfort and wellness. Testa-Seat supplies its innovative solutions to rehabilitation centers, hospitals, and private customers, ultimately promoting better mobility and overall well-being for disabled children and adults, along with their families.

MetasTx is a healthcare firm established in 2021, focused on developing innovative therapies aimed at preventing and treating prostate cancer metastasis. The company specializes in creating treatments that specifically target cancer metastasis without adversely affecting the androgen system, which is commonly impacted by traditional therapies. By concentrating on a well-known enzyme that plays a crucial role in cancer initiation and metastasis, MetasTx aims to provide effective solutions for patients suffering from prostate, breast, and skin cancers.

Resilient Lifescience is a company dedicated to combating opioid overdose deaths through innovative technology. It has developed a wearable medical device that detects opioid overdoses and automatically administers naloxone, a medication used to counteract opioid effects, thereby mitigating the risks associated with these life-threatening situations. This device empowers patients to take control of their safety and potentially save lives, even in circumstances where immediate assistance from bystanders is unavailable. By focusing on creating effective and accessible medical systems, Resilient Lifescience seeks to make a significant impact on public health and safety in the face of the opioid crisis.

Magnify Biosciences specializes in advanced microscopy solutions, offering a high-resolution imaging platform and associated services. Their technology physically expands biological samples, enabling researchers to study complex structures and molecular interactions at the nanoscale, beyond the typical limits of light microscopy. This empowers researchers, entrepreneurs, and diagnostic labs to gain unique insights into cellular architecture, facilitating advancements in life sciences and diagnostics.

D.Sole is a healthcare technology company focused on advancing remote patient monitoring in podiatry through innovative multimodal foot insoles. These insoles are designed for the early detection and monitoring of diabetic foot complications, including ulcers and deformities. By integrating advanced machine learning algorithms, D.Sole provides clinicians with comprehensive foot physiological data, enabling evidence-based insights for targeted treatments. The company's insoles are significantly more affordable than current market options, capable of detecting 15 types of foot complications, in contrast to competitors that only identify one. D.Sole aims to reduce healthcare costs substantially, potentially saving wound clinics over $100 million annually by lowering readmission rates for foot complications. Additionally, private insurers could save over $1 billion by reducing expenses related to amputations and wound care.

Finish Robotics is a company that develops mobile robotics technology aimed at addressing the labor shortage in the construction industry. It specializes in creating semi-autonomous, collaborative robots constructed from standard industrial components. These robots are designed to assist contractors in overcoming challenges related to labor availability, thereby enhancing productivity on construction sites. By leveraging innovative robotics solutions, Finish Robotics seeks to provide effective tools that improve the efficiency and effectiveness of construction operations.

Foundera Beauty is the beauty brand to shop and search for foundation and concealer online by the use of artificial intelligence.

FoodSocial is a digital recipe creator and cooking platform focused on promoting healthy cooking. The platform enables creators and brands to share their recipes and food-related content, facilitating a space for users to discover, meal plan, and shop for their favorite recipes. By doing so, FoodSocial inspires individuals to engage with nutritious cooking while supporting the creators they admire. The service aims to enhance the culinary experience by making it easier for users to access and enjoy diverse recipes tailored to their dietary preferences.

AdSkate operates a digital advertising technology platform that leverages machine learning and AI to enhance the efficiency and transparency of ad buying and selling processes. The company offers services such as campaign planning, direct buy analysis, programmatic integration, content discovery, and content analysis, empowering brands to advertise more effectively and make data-driven decisions when purchasing ad spaces.

UpContent, LLC is a technology company based in Pittsburgh, Pennsylvania, that specializes in content discovery and curation. Founded in 2015, it offers a software-as-a-service (SaaS) platform designed to help marketing, sales, and human resource teams efficiently discover and share relevant third-party digital content. The platform automates the content discovery process, allowing users to find brand mentions and engage their audiences through various channels, including social media. It features UpContent Gallery, which enables users to curate content, create custom calls-to-action, and implement retargeting strategies to capture traffic. By streamlining the content curation process, UpContent empowers organizations to enhance their communication and establish thought leadership in their respective fields.

Shelfmark is an intelligence platform focused on enhancing inventory management for suppliers, retailers, and eCommerce partners. The company has developed a remote inventory management system that provides access to comprehensive product data, allowing businesses to optimize their inventory processes. By offering tools that support various aspects of inventory management, from forecasting to replenishment, Shelfmark aims to deliver valuable insights that improve supply chain efficiency and decision-making. Its innovative approach to direct store delivery (DSD) ensures that clients can effectively manage their inventory needs in a dynamic retail environment.

EKTO VR, Inc. is a technology company based in Pittsburgh, Pennsylvania, focused on developing innovative solutions for virtual reality experiences. Incorporated in 2018, EKTO VR specializes in wearable robotic boots that facilitate locomotion within virtual environments. These boots are engineered with rotating plates that adapt to the user’s walking direction and a unique wheel system that creates a natural walking sensation while allowing individuals to remain stationary. This design not only enhances the realism of training simulations but also aims to reduce motion sickness, providing users with an immersive experience without the risks associated with physical movement in real space. EKTO VR's products are particularly geared towards enhancing virtual reality games and training applications, making it a significant player in the evolving landscape of immersive technology.

Circadiance LLC is a medical device manufacturing company based in Turtle Creek, Pennsylvania, specializing in respiratory products for individuals with sleep-disordered breathing and those requiring non-invasive ventilation. Founded in 2006, the company develops and markets a range of innovative solutions, including the SleepWeaver all-cloth positive airway pressure masks that enhance comfort during sleep, and the SmartMonitor 2, a portable apnea monitor designed for infants that tracks heart and respiration activity. Additionally, Circadiance offers the SmartMonitor 2 Professional Series for healthcare providers, providing detailed monitoring data, as well as neonatal/pediatric electrodes and the Synergy-E Event Software for analyzing infant apnea data. The NeoPAP system is also part of their product line, designed to treat newborns experiencing respiratory distress syndrome. Circadiance products are distributed through durable medical equipment providers, online retailers, and directly to healthcare professionals, both domestically and internationally.

TalkMeUp is an innovative company focused on enhancing communication skills within organizations, addressing the substantial corporate training market. It offers an AI-driven platform that provides on-demand, personalized coaching tailored to the specific needs of employees. Users can access the platform via their smartphones or computers, receiving instant, objective feedback on their communication performance, which includes aspects such as delivery style and content. TalkMeUp's services are designed to empower employees across various sectors, including retail, education, and hospitality, making it suitable for a wide range of roles, from sales to customer service. By leveraging advanced technology, TalkMeUp aims to improve overall employee competency in diverse professional scenarios.

Agot is a technology company specializing in computer vision solutions tailored for the Quick Service Restaurant (QSR) industry. Their platform digitizes restaurant activities, transforming visual data into real-time team interactions and valuable insights to enhance operational efficiency. Key benefits include reduced online order errors, increased order volume and ratings, improved pickup time estimates, and actionable operations analytics.

DisSolves Inc. is a Pittsburgh-based company specializing in the development and manufacture of dissolvable packaging materials for the food industry. Founded in 2016, DisSolves creates innovative, edible packaging made from natural and plant-based ingredients, specifically designed for single servings of drink mixes such as protein powder and flavor enhancers. Their flagship product, a pod, replaces traditional non-recyclable packaging with a more convenient, environmentally friendly option. DisSolves is committed to sustainability, utilizing renewable and vegan materials such as seaweed and polysaccharides to ensure their packaging is both degradable and safe for consumption. The company aims to enhance consumer convenience while promoting health and environmental responsibility, addressing the growing demand for efficient and eco-friendly food packaging solutions.

Leaficient is a technology company that specializes in energy-saving solutions for Controlled Environment Agriculture (CEA). It develops and deploys low-cost cameras and sensors that monitor plant biometrics and growth, enabling clients to optimize energy usage and enhance crop yield and quality predictably.

Adrich, Inc. is a company based in Pittsburgh, Pennsylvania, that specializes in electronic packaging hardware and customized software designed to enhance product usage data collection and analysis. Founded in 2015, Adrich has developed a consumer insights platform that autonomously gathers and transmits data through innovative product labels. This system captures real-time information, including day, time, geolocation, and volumetric usage data, allowing brands and retailers to gain valuable insights into consumer trends, behaviors, and usage patterns. By connecting brands with retailers and leveraging product usage analytics, Adrich aims to improve consumer engagement and retention.

Grasp Robotics is evolving into a robotics firm with a wide range of robotic solutions targeted to certain sectors and applications where robots are unable to perform critical jobs.

Realyze Intelligence specializes in AI and machine learning-based software solutions for clinical data analysis. The company develops technology designed to interpret both detailed clinical notes and structured data from electronic medical records. By leveraging natural language processing, Realyze Intelligence captures narrative data to create comprehensive patient case studies. This enables clinicians to accurately identify specific patient populations suffering from chronic diseases and cancer. The platform ultimately aims to enhance healthcare providers' ability to deliver timely and effective treatments to patients in need.

InceptEV is a technology company specializing in electric vehicle (EV) data solutions for fleet operations. It leverages proprietary data and patented technology to simulate and optimize fleet performance, enabling businesses to make informed decisions about EV adoption and plan for their operational needs.

Aquatonomy provides underwater robot autonomy software that includes localization, mapping, and planning.

Voaige is a company specializing in the development of advanced robotics and automation software, aimed at addressing labor shortages in various industries. Founded by a team of AI PhDs and robotics engineers from Carnegie Mellon University, Voaige focuses on utilizing cutting-edge artificial intelligence to tackle complex real-world challenges. Their versatile robotic arms are designed to be safe and affordable, making them accessible for diverse applications. Additionally, Voaige's deep space artificial intelligence platform empowers robotic developers to automate tasks that were previously deemed impossible, enhancing efficiency and reducing operational costs for clients. Through its innovative solutions, Voaige is committed to transforming the landscape of automation and artificial intelligence in production and business environments.

Velo.AI focuses on enhancing cyclist safety through its innovative product, Copilot, an AI-powered bike light that integrates advanced autonomous vehicle technology. This system features a rear-facing camera that records video of each ride, capturing critical data while providing real-time alerts to cyclists about approaching vehicles. Copilot issues audible warnings when a driver approaches dangerously and employs visual signals to inform drivers about potential hazards involving bicyclists. Additionally, the technology includes predictive risk estimation capabilities, which analyze driver behavior to promote safer cycling practices and help prevent accidents. Through these features, Velo.AI aims to improve visibility for cyclists and contribute to safer road interactions.

Peoples Energy Analytics specializes in providing a comprehensive, data-driven platform aimed at utility customer analysis and bill assistance. The company focuses on identifying customers at risk of defaulting on their energy bills, allowing utility organizations to proactively connect these individuals with financial support long before they miss payments. By offering a complete suite of services that includes strategy design, data analysis, and marketing outreach, Peoples Energy Analytics helps utility companies reduce unpaid bills and enhance revenue recovery. Their scalable and cost-effective solutions are designed to modernize customer engagement, ultimately improving the overall experience for utility customers.

Push2Spin Technologies is dedicated to the development and commercialization of innovative solutions in the fields of plastic and podiatric surgeries. The company aims to transform the global soft tissue grafting market through its unique technology designed for small-volume fat tissue harvesting, processing, and transfer. This novel approach enhances the efficiency of clinical procedures, streamlining the process while reducing time and costs for practitioners. By focusing on disruptive technologies, Push2Spin strives to improve outcomes in soft tissue grafting, ultimately benefiting both clinicians and patients.

Aquatonomy provides underwater robot autonomy software that includes localization, mapping, and planning.

Parcel Health is dedicated to revolutionizing medication packaging with its innovative, sustainable solutions. The company has created the world's first paper-based prescription bottle, which is fully brandable and compostable. This eco-friendly packaging not only addresses environmental concerns but also enhances temperature control and logistical safety during the shipping of medications, thereby minimizing in-transit damage and improving customer satisfaction. Designed to be both child-resistant and elderly-friendly, Parcel Health's products aim to streamline pharmacy workflows and reduce medication errors. By offering these sustainable alternatives, the company supports pharmacies and pharmaceutical companies in achieving their carbon neutrality goals while providing a reliable and efficient packaging solution.

Mamalux is a company that specializes in creating innovative, leakproof apparel designed for maternity and breastfeeding. Operating through an online store, Mamalux offers a range of personal luxury items, including gowns for nursing women and comfort-focused sleepwear for postpartum mothers. The company aims to enhance the shopping experience by providing a variety of stylish choices that promote both self-care and practicality for new mothers. By focusing on quality materials and functional designs, Mamalux addresses the unique needs of its customers while enabling them to maintain their sense of style during and after pregnancy.

Leaficient is a technology company that specializes in energy-saving solutions for Controlled Environment Agriculture (CEA). It develops and deploys low-cost cameras and sensors that monitor plant biometrics and growth, enabling clients to optimize energy usage and enhance crop yield and quality predictably.

Velo.AI focuses on enhancing cyclist safety through its innovative product, Copilot, an AI-powered bike light that integrates advanced autonomous vehicle technology. This system features a rear-facing camera that records video of each ride, capturing critical data while providing real-time alerts to cyclists about approaching vehicles. Copilot issues audible warnings when a driver approaches dangerously and employs visual signals to inform drivers about potential hazards involving bicyclists. Additionally, the technology includes predictive risk estimation capabilities, which analyze driver behavior to promote safer cycling practices and help prevent accidents. Through these features, Velo.AI aims to improve visibility for cyclists and contribute to safer road interactions.

Ariel Precision Medicine, Inc. is an integrated genomics and digital health company focused on providing precision medicine solutions for the diagnosis, monitoring, and treatment of complex chronic diseases and disorders. Founded in 2015 and headquartered in Pittsburgh, Pennsylvania, the company develops innovative clinical decision support tools aimed at simplifying personalized treatment in both emergency departments and clinical settings. One of its key offerings is ArielDx, a cloud-based tool designed to enhance the diagnosis and treatment of pancreatic disease, thereby improving patient outcomes through tailored healthcare solutions.

Module is a company focused on developing modular residential housing projects that emphasize intelligent architectural design. By employing a modular approach, the company aims to make homeownership more accessible and flexible for a broader audience. Its offerings enable buyers to secure the right amount of living space tailored to their needs, while also providing customized housing services. This innovative model positions Module as a provider of affordable housing solutions suitable for the urban environment, catering to the demands of contemporary living.

Apollo Neuroscience, Inc. is a Pittsburgh-based company that manufactures a clinically validated wearable wellness device designed to assist the body in recovering from chronic stress through gentle vibrations. Established in 2016, the company also offers an application that integrates neuroscience and machine learning to enhance heart rate variability, promoting improved routines for waking, focusing, unwinding, and engaging the parasympathetic nervous system. The product is marketed directly to consumers through online sales and is positioned as a wellness solution rather than a treatment for psychiatric disorders.

Forest Devices, Inc. is a medical device company based in Pittsburgh, Pennsylvania, with an additional office in Canada. Founded in 2014, the company specializes in developing innovative solutions for stroke detection. Its flagship product, AlphaStroke, is a portable and non-invasive stroke screening device that assists medical personnel in identifying early signs of both ischemic and hemorrhagic strokes. By enabling pre-hospital providers to accurately assess patients, AlphaStroke facilitates timely triage and enhances decision-making in critical care scenarios, ultimately aiming to reduce treatment delays and improve patient outcomes.

Make It Home Safe is a mobile application founded in 2017 and headquartered in Pittsburgh, Pennsylvania, that focuses on enhancing safety and security during traffic stops. The app serves as a tool for both motorists and law enforcement, providing real-time identity verification to facilitate smoother interactions. By aiming to reduce tensions between police and the public, Make It Home Safe seeks to create a safer environment on the road, helping to assure users that their safety is prioritized during potentially stressful encounters.

Optimus Technologies is a clean energy technology company headquartered in Pittsburgh, Pennsylvania. It specializes in developing advanced fuel management systems that enable medium and heavy-duty truck fleets to operate on 100% biodiesel. The company's flagship product, the Vector System, integrates seamlessly into existing diesel engines without the need for extensive modifications or replacements. This technology allows fleet operators to achieve significant reductions in fuel costs and emissions while effectively meeting renewable fuel targets. By providing a practical solution for transitioning to low-carbon fuels, Optimus Technologies addresses the challenges of emissions reductions in heavy-duty applications.

SpIntellx, Inc. is a computational and systems pathology company based in Pittsburgh, Pennsylvania, that specializes in spatial intelligence software products designed for analyzing pathology tissue sections in cancer diagnosis. Founded in 2017, the company offers innovative solutions such as SpIntellx, which processes image data sets from various imaging platforms and reagents, and HistoMapr, a computational guide for pathologists. Additionally, TumorMapr is utilized to analyze the spatial interactions of biomarkers within whole slide images using multiplexed fluorescence. With a focus on Precision Pathology and Spatially Intelligent Biology, SpIntellx leverages unbiased spatial analytics powered by explainable AI to enhance understanding of complex cancer biology, thereby facilitating advancements in drug development, diagnostics, and treatment strategies.

Kloopify is a prominent platform focused on reducing emissions associated with purchased goods and services. It offers a comprehensive solution that allows businesses to track, reduce, and report their supply chain's carbon footprint. By providing a holistic overview of environmental emissions, Kloopify enables organizations to make informed procurement decisions that align with their sustainability goals. The software not only aids in accelerating revenue growth but also helps mitigate risks related to environmental impact, making it an essential tool for companies committed to sustainable practices.

Duo Oncology is a biotechnology company focused on developing innovative nanoparticle technology designed to penetrate established tumors, particularly targeting hard-to-treat cancers such as pancreatic cancer and bile duct cancer. By collaborating closely with leading university scientists and medical oncologists, Duo Oncology aims to redefine treatment outcomes through a novel monotherapy approach that enhances patient care. The company's research is supported by a network of established research organizations, enabling efficient and rapid development of its products. With a commitment to advancing immunotherapy and precision medicine, Duo Oncology seeks to improve recovery times and overall treatment efficacy for patients facing challenging diagnoses.

Webvizio is a visual feedback collaboration and productivity platform designed to enhance communication among digital teams and clients during web development projects. The platform facilitates real-time collaboration on live web pages and applications, allowing users to provide visual feedback directly on web elements. It helps streamline the development process by minimizing the need for back-and-forth communication through various channels, such as email and video calls. Users can manage multiple projects simultaneously, assign tasks, set deadlines, and track progress in real time. Webvizio also offers screen recording capabilities and integrates with other productivity software, enabling web builders and team managers to improve overall productivity and efficiency in their workflows.

Toyz Electronics is a Pennsylvania-based company that specializes in developing innovative technology solutions for the education sector. The company focuses on a gamified learning platform aimed at empowering students to acquire skills in STEAM (science, technology, engineering, art, and math), as well as entrepreneurship and storytelling. Through a unique approach that incorporates a superhero rap concept, Toyz Electronics offers a project-based curriculum that is culturally relevant and responsive. The platform utilizes elements such as hip-hop culture, music, gaming, three-dimensional models, comics, and design to engage students effectively. This comprehensive approach enables learners to develop a diverse range of technical and soft skills while creating their own superhero avatars and sharing personal narratives.

Honeycomb Credit, Inc. operates a peer-to-peer lending platform that connects small business owners with individual investors seeking to fund those businesses. Founded in 2017 and based in Pittsburgh, Pennsylvania, the company allows businesses to secure loans from their own customers and community members, facilitating debt crowdfunding. This innovative approach enables small businesses to obtain necessary capital without relinquishing equity, thus supporting their growth while providing a unique investment opportunity for lenders. By bridging the gap between traditional funding sources and community support, Honeycomb Credit enhances access to financial resources for small enterprises.

Revitalize Energy is a consumer-focused company that develops eye drops aimed at alleviating fatigue associated with prolonged screen use. The product features a patented blend of stimulants and amino acids designed to moisturize the eyes and provide instant relief from tiredness. By applying just 1-2 drops, users experience a refreshing effect that helps combat the discomfort caused by digital devices, allowing them to feel revitalized and more alert. The company's innovative approach addresses a growing concern in today's technology-driven environment, where eye strain and fatigue have become increasingly common.

Setex Technologies, founded in 2009 and based in Pittsburgh, Pennsylvania, is a pioneering manufacturer of micro-fibrillar polymer-based dry adhesives and gripping surfaces. As a spin-out from Carnegie Mellon University, the company focuses on providing innovative solutions that address complex manufacturing challenges across various sectors, including industrial manufacturing, sports, medical, and consumer goods. Setex’s dry adhesive technology not only enhances grip and anti-slip capabilities in diverse products but also enables product designers and engineers to explore creative, market-leading designs that traditional adhesives and gripping materials may not effectively support.

LeanFM Technologies is a developer of cloud-based software designed to streamline facility management by providing easy access to actionable information. The company's platform integrates static design information and dynamic measurements, utilizing standard communication protocols to enhance data accessibility. By automatically mapping data points from building automation systems to design drawings, LeanFM Technologies enables facility managers in various sectors, including hospitals and universities, to make informed, data-driven decisions. The platform also offers insights into maintenance history and backlog, augmented by artificial intelligence, allowing clients to minimize waste and maximize value for both owners and occupants.

Operator of a SaaS-based healthcare price transparency platform intended to aggregate and contextualize price transparency, insurance, and demographic data. The company's platform offers health plans a simple way to comply with the CMS (Centers for Medicare and Medicaid Services) price transparency legislation while digitizing how patients shop, book, and pay for healthcare, enabling users to realize average cost savings to guide every healthcare purchasing decision.

InnSight Technology is a biotechnology company focused on advancing the diagnostics and evaluation of eye diseases. The company specializes in developing innovative ophthalmic devices, including a novel, hand-held biosensor designed for the detection of anterior ophthalmic injuries. Additionally, InnSight Technology works on the development of nanotechnology-based medical devices aimed at addressing various clinical needs in ophthalmology. By providing these advanced tools, the company enables clinicians to enhance ocular care and improve patient outcomes in eye health.

NOCTEM Health is a clinical decision support tool focused on addressing insomnia and other sleep disturbances through innovative telehealth solutions. The company provides a platform that enhances patient workflows and delivers effective behavioral sleep treatments by integrating interactive and adaptive tools. This approach combines high-quality sleep care with the cost-efficiency of digital technologies, allowing patients to connect with therapists for real-time assessment, monitoring, and treatment. By empowering clinicians, NOCTEM Health aims to improve the overall delivery of sleep care and meet the unmet healthcare needs in the field of sleep medicine.

Gus Gear is a manufacturer of wearable securement clothing designed to protect implanted medical devices and enhance patient outcomes. The company's flagship product, the Central Line Vest, safeguards central catheters from damage, breakage, and accidental removal, allowing patients to maintain their quality of life while undergoing treatment. In addition to the Central Line Vest, Gus Gear's platform offers securement solutions for various medical devices, including ostomy pouches and feeding tubes. By using innovative securement systems, Gus Gear enables patients to manage their medical challenges effectively, promoting independence and wellbeing.

Respair is a medical device company focused on developing advanced airway products designed for critical care environments. The company's innovative technology replaces traditional inflatable cuffs utilized in breathing tubes with soft, pliable baffles that serve as effective stoppers, ensuring a comprehensive seal of the airway without applying additional pressure. This design enhancement allows patients to breathe more easily and reduces the risk of secondary complications, thereby supporting both clinicians and patients in high-stakes medical settings.

Buoy is a manufacturer of hydrating wellness drops designed to enhance the hydration potential of any beverage. The company's products contain a blend of full-spectrum electrolytes, vitamins, ionic trace minerals, and antioxidants that dissolve instantly and evenly, making it easy for consumers to improve their hydration without sacrificing taste. As many Americans experience chronic dehydration due to various factors such as exercise, diet, and environmental conditions, Buoy provides a practical solution for individuals looking to maintain optimal hydration levels. By allowing users to add essential nutrients to the drinks they already enjoy, Buoy aims to help people stay energized and clear-minded throughout the day.

Voaige is a company specializing in the development of advanced robotics and automation software, aimed at addressing labor shortages in various industries. Founded by a team of AI PhDs and robotics engineers from Carnegie Mellon University, Voaige focuses on utilizing cutting-edge artificial intelligence to tackle complex real-world challenges. Their versatile robotic arms are designed to be safe and affordable, making them accessible for diverse applications. Additionally, Voaige's deep space artificial intelligence platform empowers robotic developers to automate tasks that were previously deemed impossible, enhancing efficiency and reducing operational costs for clients. Through its innovative solutions, Voaige is committed to transforming the landscape of automation and artificial intelligence in production and business environments.

PECA Labs, Inc. is a medical device company based in Pittsburgh, Pennsylvania, focused on developing innovative solutions for pediatric cardiovascular conditions. The company specializes in the MASA Valve, a synthetic valved conduit designed for right ventricular outflow tract reconstruction in children. This device incorporates advanced material properties of ePTFE and a unique valve design to address the limitations of existing conduits. In addition to the MASA Valve, PECA Labs offers exGraft, an ePTFE vascular graft marked for enhanced visibility during procedures. The MASA Valve has received a Humanitarian Use Device designation from the FDA and has demonstrated improved outcomes in clinical use, reducing the need for re-operation compared to traditional options. Founded in 2011 as a spin-off from Carnegie Mellon University and UPMC, PECA Labs is committed to providing better medical devices for underserved populations.

Inspired Cognition is a Pennsylvania-based company that specializes in developing artificial intelligence software tailored for the research and development lifecycle. The company focuses on creating digital tools and online systems that assist businesses in integrating AI solutions effectively. Its products provide evaluation as a service, enabling organizations to monitor, analyze, and improve their operational plans. Additionally, Inspired Cognition’s offerings include data modeling capabilities that help business professionals identify system pain points and propose actionable solutions. Through its innovations, Inspired Cognition aims to support businesses in leveraging AI to enhance their operations and decision-making processes.

Advanced Optronics specializes in the design and manufacture of implantable sensors aimed at enhancing intraoperative monitoring during surgical procedures. The company focuses on developing flexible, biocompatible sensor systems that facilitate less traumatic insertions, thereby minimizing trauma and protecting residual hearing during cochlear implant surgeries. By integrating advanced flexible micro-electromechanical system sensors with cochlear implants, Advanced Optronics enables surgeons to achieve improved surgical outcomes and enhance patient safety across various medical applications.

UpContent, LLC is a technology company based in Pittsburgh, Pennsylvania, that specializes in content discovery and curation. Founded in 2015, it offers a software-as-a-service (SaaS) platform designed to help marketing, sales, and human resource teams efficiently discover and share relevant third-party digital content. The platform automates the content discovery process, allowing users to find brand mentions and engage their audiences through various channels, including social media. It features UpContent Gallery, which enables users to curate content, create custom calls-to-action, and implement retargeting strategies to capture traffic. By streamlining the content curation process, UpContent empowers organizations to enhance their communication and establish thought leadership in their respective fields.

BioHybrid Solutions is a biotechnology company that specializes in developing advanced nanoarmored protein-polymer conjugates. The company focuses on tailoring the activity and stability of proteins and enzymes for various applications. Utilizing atom transfer radical polymerization chemistry, BioHybrid Solutions precisely grows polymers from the surface of proteins, enhancing their functionality. Through its research and development efforts, the company aims to provide innovative alternatives for therapeutics and protein engineering, ultimately contributing to advancements in medical treatments.