Avisi Technologies
Seed Round in 2022
Avisi Technologies Inc. is a Philadelphia-based company founded in 2017 that specializes in developing innovative solutions for glaucoma treatment. Its primary product, VisiPlate, is a next-generation, nanotechnology-enabled aqueous shunt designed to prevent blindness caused by glaucoma. Through its advanced technology, Avisi Technologies aims to enhance the effectiveness of glaucoma management and improve patient outcomes.
AmorSui
Seed Round in 2022
Founded in 2020, AmorSui is a pioneering company specializing in the design and innovation of medical gowns and lab jackets for healthcare professionals. Their products are antimicrobial, static-resistant, protective against bodily fluids, reusable, and recyclable.amorSui delivers premium quality, comfortable, and eco-friendly PPE made and sourced entirely in the USA.
Nia Therapeutics
Venture Round in 2021
Nia Therapeutics, Inc. is a company focused on developing precision neurostimulation therapies aimed at treating memory impairment, particularly in patients with traumatic brain injury. Founded in 2016, Nia Therapeutics is based in Radnor, Pennsylvania. The company's innovative approach involves utilizing neurostimulation devices that interpret complex brain activity related to memory function. By providing personalized therapy through deep-brain stimulation, Nia Therapeutics aims to enhance memory restoration and improve cognitive outcomes for affected individuals.
Vesteck is a clinical-stage medical device company specializing in innovative solutions for aortic repair, structural heart, and gastrointestinal markets. Its flagship product, the Suture-Tight™ nitinol suture delivery catheter, aims to address significant global challenges in endovascular aortic repair by providing a novel technology for physicians and patients.
Avisi Technologies
Seed Round in 2021
Avisi Technologies Inc. is a Philadelphia-based company founded in 2017 that specializes in developing innovative solutions for glaucoma treatment. Its primary product, VisiPlate, is a next-generation, nanotechnology-enabled aqueous shunt designed to prevent blindness caused by glaucoma. Through its advanced technology, Avisi Technologies aims to enhance the effectiveness of glaucoma management and improve patient outcomes.
Pression
Pre Seed Round in 2020
Pression is a developer of a patented, non-invasive smart compression platform known as the Wave. This system is designed to enhance circulation throughout the body and improve cardiac function, with a primary focus on supporting heart failure patients. By mobilizing excess retained fluids, which is a leading cause of hospitalization in the United States, the Wave aims to increase oxygen delivery to vital organs and enhance overall quality of life. The platform leverages proven scientific principles while addressing the limitations of previous systems, ultimately promoting greater independence and improved exercise tolerance for patients suffering from circulatory conditions.
Excision BioTherapeutics
Debt Financing in 2020
Excision BioTherapeutics Inc. is a life science company based in Philadelphia, Pennsylvania, established in 2015. The company is dedicated to the development and commercialization of gene editing therapeutics aimed at treating life-threatening diseases caused by neurotropic viruses. Utilizing CRISPR-based technology, Excision BioTherapeutics focuses on creating advanced gene-editing medicines that can eradicate or disrupt viral genes in human patients. The company's mission is to advance these therapeutics into safe and effective treatments, significantly improving the lives of individuals affected by viral infections globally.
OsciFlex
Debt Financing in 2020
OsciFlex LLC, established in 2017 and headquartered in Philadelphia, Pennsylvania, specializes in developing a medical device aimed at preventing blood clots from forming at valves. The company's innovative product mimics nature's process to provide more effective compression therapy, reducing the risk of Venous thromboembolism (VTE) in patients and potentially decreasing reliance on costly and risky anti-coagulation pharmaceuticals.
iOrtho+
Debt Financing in 2020
iOrtho+ is a medical software company specializing in orthopedic care through its innovative product, the Mobil-Aider. This web-based application is designed to quantify joint mobility and allows clinicians to assess at least 14 motions across five different joints. The Mobil-Aider features a vast array of resources, offering 450 tests, 1,300 references, and 100 mobilization techniques. It serves as a comprehensive reference tool for orthopedic professionals, providing concise descriptions, images, videos, and statistical data, all of which enhance the clinician's ability to improve treatment outcomes and techniques.
Bainbridge Health
Debt Financing in 2020
Bainbridge Health, Inc. is a Philadelphia-based company founded in 2016 that specializes in developing a clinical intelligence and data analytics platform aimed at enhancing medication safety in hospital settings. The company's offerings include a vendor-agnostic medication safety platform that streamlines data management, reducing the reliance on manual data clerking and ad-hoc reporting. Their solutions, designed for medication safety leaders and hospital safety professionals, include an infusion pump management software known as InfusionWare, which centralizes infusion data to improve patient safety and effectively manage pump information. By mitigating medication errors, Bainbridge Health's platform helps healthcare providers reduce avoidable costs and improve overall patient care.
Aevumed
Debt Financing in 2020
Aevumed is a privately-owned company focused on developing innovative medical devices aimed at improving treatment outcomes for rotator cuff tears. The company's flagship device enhances healing by providing superior pull-out strength and suture retention, which facilitates better integration between tendon and bone. This technology addresses the critical issue of retear rates in rotator cuff surgeries, offering patients both mechanical support and biological enhancement. Aevumed is dedicated to improving quality of life through its continuous commitment to innovation and quality, as well as its strategic expansion into new territories.
Pression is a developer of a patented, non-invasive smart compression platform known as the Wave. This system is designed to enhance circulation throughout the body and improve cardiac function, with a primary focus on supporting heart failure patients. By mobilizing excess retained fluids, which is a leading cause of hospitalization in the United States, the Wave aims to increase oxygen delivery to vital organs and enhance overall quality of life. The platform leverages proven scientific principles while addressing the limitations of previous systems, ultimately promoting greater independence and improved exercise tolerance for patients suffering from circulatory conditions.
RightAir is focused on creating innovative noninvasive ventilators aimed at assisting patients with chronic obstructive pulmonary disease (COPD). The company's flagship product, AIR-AD, is a wearable device that resembles a vest and employs proven respiratory assist technology known as cuirass ventilators. This device alleviates the effort required for breathing by generating a vacuum that aids in lifting the chest and abdomen during inhalation, while also increasing pressure over the chest to facilitate faster exhalation. By adjusting the patient's natural breathing patterns during both rest and exercise, AIR-AD helps alleviate feelings of breathlessness, allowing users to engage more fully in their daily activities.
DRSLINQ is developing a mobile EKG device that is coupled to an interactive application powered by a natural language processing integrated with a machine learning platform to appropriately triage chest pain patients to the ER.
Optical Inventory Solutions
Grant in 2020
Optical Inventory Solutions is the developer of ViewVax, a leading automated vaccine inventory management system. ViewVax seamlessly integrates with existing medical refrigerators, allowing hospitals, clinics, and doctors' offices to optimize their vaccine storage while utilizing advanced hardware and software. The system features a web-connected camera that accurately counts on-hand vaccine inventory, facilitating automatic reordering and reducing excess stock levels. This innovative solution not only simplifies the management of vaccines but also enhances operational efficiency by providing precise data recognition and maintaining proper inventory levels in cold storage environments.
Cogwear is a brain technology company focused on assisting individuals who experience anxiety and depression. The company is developing an advanced wearable device that transcends existing products by integrating cognitive and emotional insights with physical measurements. This innovation aims to enhance human health, safety, and performance. Cogwear utilizes AI-powered algorithms to provide users with real-time access to clinical-grade cognitive and emotional data in various environments. Its wearables are equipped with mobile electroencephalogram (EEG) sensors and machine learning technology, allowing for the accurate measurement and interpretation of brainwave activity. The proprietary dry EEG sensors are designed for comfort and precision, enabling users to track their brain activity through a secure application and shareable dashboard.
Hava Health
Pre Seed Round in 2019
Hava Health, Inc. is a biotechnology company based in the United States that specializes in developing innovative solutions for nicotine addiction. The company manufactures a smoking cessation device, which includes a connected vape pen that integrates with a smartphone application called Hale. This digital drug therapy device aims to support individuals in their efforts to quit smoking by providing a modern approach to nicotine de-addiction. Through its technology, Hava Health seeks to enhance the effectiveness of smoking cessation efforts and improve health outcomes for users.
Avisi Technologies
Seed Round in 2019
Avisi Technologies Inc. is a Philadelphia-based company founded in 2017 that specializes in developing innovative solutions for glaucoma treatment. Its primary product, VisiPlate, is a next-generation, nanotechnology-enabled aqueous shunt designed to prevent blindness caused by glaucoma. Through its advanced technology, Avisi Technologies aims to enhance the effectiveness of glaucoma management and improve patient outcomes.
MBF Therapeutics
Seed Round in 2018
MBF Therapeutics, Inc. is a veterinary oncology company based in Ambler, Pennsylvania, focused on developing and commercializing innovative therapies for cancer treatment in dogs and cats. The company specializes in targeted immunotherapies and small molecule drugs that effectively disrupt tumor cell metabolism while preserving healthy cells and organs. Its product portfolio includes MBFT-101, a combination therapy for sarcomas and lymphoma, featuring a proprietary polyamine transport inhibitor and a potent inhibitor of ornithine decarboxylase, as well as MBFT-102, an immunotherapy based on the tumor suppressor/cytokine mda-7/IL24, which has shown promise in human cancers. Additionally, MBF Therapeutics employs a proprietary DNA vaccine platform and delivery system to develop immunotherapeutic vaccines aimed at enhancing protective immunity against infectious diseases in companion animals and livestock. The company maintains a strategic partnership with the Lankenau Institute for Medical Research to further advance its research and development initiatives.
SonoSolve
Seed Round in 2016
SonoSolve is a revolutionary new device that aims to eliminate catheter-associated complications, using non-invasive sound waves to clear obstructions and biofilms within catheters. SonoSolve is the BUZZ in Blockages!
Shock Analytics
Seed Round in 2016
Shock Analytics LLC is an early-stage biomedical device company based in Philadelphia, Pennsylvania, established in 2016. The firm specializes in the design and manufacture of noninvasive diagnostic devices aimed at improving the management of acute and chronic illnesses. Its primary focus is on developing technology that estimates Systemic Vascular Resistance (SVR), a critical indicator for conditions such as congestive heart failure and sepsis. By utilizing hemodynamic information, Shock Analytics' devices enable healthcare professionals to effectively treat and monitor patients suffering from these serious medical conditions.
Cagent Vascular
Seed Round in 2016
Cagent Vascular, LLC is a medical device company that specializes in developing innovative angioplasty balloons utilizing proprietary serration technology. Incorporated in 2014 and based in Wayne, Pennsylvania, the company has created the Serranator, a unique angioplasty device featuring serrated metal strips embedded in a semi-compliant balloon. This device is designed to treat atherosclerosis by effectively addressing blocked arteries, particularly in patients with peripheral artery disease and chronic limb-threatening ischemia. Cagent Vascular's technology aims to enhance the effectiveness of vessel dilatation procedures in cardiovascular interventions, providing healthcare providers with advanced tools to improve patient outcomes.
Orange Maker
Seed Round in 2016
Orange Maker is a Thousand Oaks, California-based developer of 3D printing technology and software that enables end-to-end, flexible manufacturing. It designs and commercializes high-resolution systems such as Helios One, based on heliolithography, and provides compatible materials along with user-friendly software to professional designers and engineers worldwide. The company's solutions support applications across aerospace, architecture, automotive, biotech, medical, defense, and manufacturing, linking digital design with physical production. Founded in the mid-2010s by Doug Farber and Kurtis Dudley, Orange Maker emphasizes advanced output capabilities and aims to empower users to imagine, design, and create complex 3D objects without compromising their vision.
Defend Your Head
Seed Round in 2015
Defend Your Head, based in Chester Springs, PA, specializes in innovative helmet technology designed to reduce head injuries in contact sports, military, and industrial settings. The company has developed a patented soft shell protective helmet called the ProCap, which enhances the protective capabilities of existing helmets. Unlike traditional helmets that primarily focus on internal padding, the ProCap utilizes a unique design that absorbs and dissipates energy, reduces the speed of impact, and deflects glancing blows. Independent lab tests have demonstrated its effectiveness in minimizing sports-related injuries. The ProCap is customizable in color, compatible with decals, and resistant to extreme temperatures, offering advantages over competitor products. Founded in 2013 after a merger that built upon earlier technology developed by private investors and physicians, Defend Your Head is led by John Roman, a former NFL player, alongside Frank Lytle, an experienced product designer, and Greg Lewis, a finance and marketing professional. The company anticipates launching its product in the market in late summer.
Halo Labs
Seed Round in 2015
Halo Labs is a life science instrumentation company based in Burlingame, California. It develops tools for biologics researchers, enabling assessments such as biologics-developability, formulation development, small molecule solubility, and AAV analytics.
ZSX Medical
Venture Round in 2015
ZSX Medical is a medical device development company based in Philadelphia, Pennsylvania, founded in 2009. The company specializes in creating bio-absorbable products for internal closure in minimally invasive surgeries. Their flagship product, Zip-stitch, is a surgical closure system designed to simplify and expedite difficult surgical closures, particularly for uterine closure during cesarean deliveries. By reducing operative time and potential complications such as infection and tissue adhesion, ZSX Medical aims to improve patient outcomes and lower healthcare costs for hospitals.
TowerView Health
Seed Round in 2015
TowerView helps the 1 in 3 Americans with a chronic illness manage multiple medications. TowerView’s patients receive pre-filled medication trays that fit into a connected pillbox like a K-Cup into a Keurig coffee machine. Their pillbox can sense when patients forget a dose and automatically sends a text or phone reminder. Unlike other smart pillboxes, they send patients pre-filled medication trays sourced from a pharmacy so patients never have to fill their own pillbox and they work directly with nurses to target outreach for non-adherent patients.
TowerView is rolling out with Independence Blue Cross in January 2015 and are in advanced discussions with numerous other health plans.
Essential Medical
Seed Round in 2014
Essential Medical is a family owned & operated business that was started in 1985. We are a broad based supplier of home medical and health related products designed with the needs of the user in mind. Within this online website you will find many different product options to meet a variety of life styles and physical conditions.
If you are a home medical equipment dealer and would like to be set up to order Essential products, please click on the Prospective Dealers tab.
If you would like to purchase products for yourself, family member or friend, our fine products are available through your local medical equipment dealer or pharmacy. Please consult the yellow pages of your local telephone book under Hospital and Medical Equipment.
Infarct Reduction Technologies
Seed Round in 2014
Infarct Reduction Technologies develops a therapeutic device for ischemic pre-conditioning protocol. The company offers LifeCuff, a non-invasive manually-inflated blood pressure cuff for remote ischemic conditioning in heart attack, stroke, sepsis, liver surgery, traumatic brain injury, and other critical condition patients.
The company is headquartered in Waldwick, New Jersey.
Stabiliz Orthopaedics
Seed Round in 2014
Stabiliz Orthopaedics, LLC is a company based in Exton, Pennsylvania, that specializes in the development and distribution of orthopedic devices. Founded in 2009, the company focuses on creating innovative enhancements to orthopedic medical technologies that are FDA approved. Stabiliz Orthopaedics aims to improve clinical outcomes and reduce healthcare costs, addressing the challenges faced by healthcare systems. Through its commitment to advancing orthopedic care, the company seeks to provide effective solutions that enhance patient treatment and recovery.
Photosonix Medical
Seed Round in 2014
Photosonix Medical, headquartered in Ambler, Pennsylvania, specializes in the development of innovative skincare treatment devices. Their flagship product, CLENS™ (Coincident Light Energy and Non-focused UltraSound), synergistically combines light and ultrasound energy to effectively treat chronic bacterial infections known as biofilms, particularly targeting moderate to severe acne. The company aims to provide a convenient at-home solution for users, reducing the risk of permanent skin scarring. Their primary target prescribers are dermatologists and primary care physicians.
Defend Your Head
Seed Round in 2014
Defend Your Head, based in Chester Springs, PA, specializes in innovative helmet technology designed to reduce head injuries in contact sports, military, and industrial settings. The company has developed a patented soft shell protective helmet called the ProCap, which enhances the protective capabilities of existing helmets. Unlike traditional helmets that primarily focus on internal padding, the ProCap utilizes a unique design that absorbs and dissipates energy, reduces the speed of impact, and deflects glancing blows. Independent lab tests have demonstrated its effectiveness in minimizing sports-related injuries. The ProCap is customizable in color, compatible with decals, and resistant to extreme temperatures, offering advantages over competitor products. Founded in 2013 after a merger that built upon earlier technology developed by private investors and physicians, Defend Your Head is led by John Roman, a former NFL player, alongside Frank Lytle, an experienced product designer, and Greg Lewis, a finance and marketing professional. The company anticipates launching its product in the market in late summer.
MemVu, Inc. is a provider of brain health training solutions aimed at individuals and families. Founded in 2008 and headquartered in Shaker Heights, Ohio, the company offers a patent-pending platform that allows users to personalize brain exercises using their own photos, which can be integrated into various brain games and activities. This innovative approach enhances engagement and facilitates socialization, particularly for individuals experiencing brain health issues. MemVu’s solutions are utilized by a range of professionals, including physicians, social workers, and psychologists, as well as by hospitals, rehabilitation centers, adult daycare facilities, and assisted living communities. These resources not only support patient care but also foster connections between patients and their families, encouraging involvement in the care process through personalized photo messages and interactive exercises.
Halo Labs
Seed Round in 2014
Halo Labs is a life science instrumentation company based in Burlingame, California. It develops tools for biologics researchers, enabling assessments such as biologics-developability, formulation development, small molecule solubility, and AAV analytics.
OrthogenRx
Seed Round in 2013
OrthogenRx is a commercial-stage product development company focused on providing orthopedic medical devices for treating musculoskeletal conditions. The company specializes in developing knee joint pain injections that lubricate the joint and relieve mild to moderate knee pain for patients who have not responded well to conservative therapies or simple analgesics. OrthogenRx's business model involves securing exclusive supply and license agreements for products already available outside the U.S., aiming to obtain generic product approval within the U.S. This strategy leverages existing regulations for abbreviated regulatory approval, similar to that of generic drugs, with the potential to significantly reduce healthcare costs.
ZSX Medical
Series A in 2013
ZSX Medical is a medical device development company based in Philadelphia, Pennsylvania, founded in 2009. The company specializes in creating bio-absorbable products for internal closure in minimally invasive surgeries. Their flagship product, Zip-stitch, is a surgical closure system designed to simplify and expedite difficult surgical closures, particularly for uterine closure during cesarean deliveries. By reducing operative time and potential complications such as infection and tissue adhesion, ZSX Medical aims to improve patient outcomes and lower healthcare costs for hospitals.
S4 Worldwide
Seed Round in 2012
S4 Worldwide, LLC, based in Doylestown, Pennsylvania, specializes in the development of public safety security and surveillance products, focusing on mobile real-time situational awareness technologies for various sectors. Established in 2010, the company offers a range of innovative solutions, including GPS body cameras designed for law enforcement, docking stations for data management, and advanced drone systems for surveillance and unauthorized drone detection. S4 Worldwide's products utilize environmentally friendly, solar and wind-powered trailer-mounted systems to gather and transmit video, audio, and sensor data from remote locations to users' devices via a secure online platform. This technology aids organizations in protecting against intrusions, theft, and vandalism, while also supporting compliance with safety and regulatory standards. The company serves multiple industries, including law enforcement, military, healthcare, education, and security services.
Stabiliz Orthopaedics
Seed Round in 2012
Stabiliz Orthopaedics, LLC is a company based in Exton, Pennsylvania, that specializes in the development and distribution of orthopedic devices. Founded in 2009, the company focuses on creating innovative enhancements to orthopedic medical technologies that are FDA approved. Stabiliz Orthopaedics aims to improve clinical outcomes and reduce healthcare costs, addressing the challenges faced by healthcare systems. Through its commitment to advancing orthopedic care, the company seeks to provide effective solutions that enhance patient treatment and recovery.
EyeIC
Venture Round in 2012
EyeIC, Inc. is a medical technology company based in Wayne, Pennsylvania, specializing in the development and commercialization of imaging technologies for healthcare applications. Founded in 2004, EyeIC focuses on providing innovative solutions for eye care professionals and clinics. One of its key products, MatchedFlicker, is designed to monitor the onset and progression of glaucoma by detecting changes in time series retinal photographs. The technology automates the alignment and registration of images taken at different times, generating a superimposed view that facilitates analysis. Additionally, EyeIC's platform includes built-in interpretation and reporting tools, streamlining documentation and claims submission while assisting clinicians in identifying various retinal conditions, including diabetic retinopathy and retinopathy of prematurity. Through its advancements, EyeIC aims to enhance clinical workflows and improve patient care in the field of ophthalmology.
Essential Medical
Seed Round in 2011
Essential Medical is a family owned & operated business that was started in 1985. We are a broad based supplier of home medical and health related products designed with the needs of the user in mind. Within this online website you will find many different product options to meet a variety of life styles and physical conditions.
If you are a home medical equipment dealer and would like to be set up to order Essential products, please click on the Prospective Dealers tab.
If you would like to purchase products for yourself, family member or friend, our fine products are available through your local medical equipment dealer or pharmacy. Please consult the yellow pages of your local telephone book under Hospital and Medical Equipment.
Essential Medical
Seed Round in 2010
Essential Medical, Inc. is a medical device company based in Malvern, Pennsylvania, that specializes in the development and marketing of femoral artery vascular closure devices. Founded in 2010, the company focuses on sealing femoral punctures that occur after diagnostic and interventional cardiac catheterization procedures. Essential Medical has developed two key devices, including MANTA, which is designed to close large bore punctures ranging from 10 to 24 French following various vascular access procedures such as transcatheter aortic valve replacement, abdominal aortic aneurysm repair, and balloon aortic valvuloplasty. These closures are critical in the rapidly growing field of interventional cardiology, enabling physicians to address the need for efficient and complication-free closure solutions. As of October 2018, Essential Medical operates as a subsidiary of Teleflex Incorporated.
Bionano Genomics
Seed Round in 2006
Bionano Genomics, Inc. is a biotechnology company focused on genome mapping and analysis. It develops and markets the Saphyr system, an advanced platform designed for ultra-sensitive and specific detection of structural variations in DNA, such as insertions, deletions, and translocations, which are often linked to genetic disorders and diseases, including cancer. The Saphyr system employs optical genome mapping technology, allowing for direct visualization and analysis of long DNA molecules without relying on sequencing. This capability provides researchers and clinicians with critical insights into the structural variations within genomes, enhancing the understanding of disease mechanisms and supporting the development of personalized treatment strategies. Bionano Genomics also offers essential reagents and data solutions, including Bionano prep kits, labeling kits, and software tools for comprehensive experiment management. Its products are primarily sold to academic and governmental research laboratories, as well as pharmaceutical, biotechnology, and contract research organizations across multiple regions, including North America, Europe, and Asia. Founded in 2003 and headquartered in San Diego, California, the company was previously known as BioNano Genomics, Inc. until its name change in July 2018.