Ben Franklin Technology Partners of Southeastern Pennsylvania

PolyCore Therapeutics is focused on developing innovative treatments for central nervous system (CNS) disorders, specifically targeting dyskinesia and cognitive impairment. The company aims to create new, affordable therapies that address the side effects associated with the treatment of Parkinson's disease and other neurological conditions. By enhancing patient mobility and quality of life, PolyCore Therapeutics seeks to contribute to more effective management of these disorders while also aiming to reduce overall healthcare costs. Their experienced team of scientists and life sciences professionals is dedicated to advancing research in this critical area of healthcare.

Astarte Medical, established in 2016 and headquartered in Yardley, Pennsylvania, specializes in developing software for clinical intelligence. Its platform offers a real-time, comprehensive view of clinical data, focusing on the gut health of preterm infants in Neonatal Intensive Care Units (NICUs). By standardizing and streamlining feeding practices, Astarte Medical empowers clinical care teams to make more informed decisions, ultimately enhancing patient outcomes and optimizing care for vulnerable pediatric populations.

RecoveryLink is a developer of a digital recovery support platform aimed at improving behavioral health outcomes. The platform provides a comprehensive suite of services, including electronic recovery records, asynchronous digital training, individual telerecovery peer services, and live video group-based recovery support. By offering these tools, RecoveryLink seeks to enhance accessibility and effectiveness in recovery support, ultimately transforming systems within the behavioral health sector.

iOrtho+ is a medical software company that specializes in orthopedic care through its innovative web-based application, the Mobil-Aider. This premium orthopedic app is designed to quantify joint mobility, enabling clinicians to assess a wide range of motions across multiple joints. The Mobil-Aider includes 450 tests and 1,300 references, along with 100 mobilization techniques, offering a comprehensive resource for orthopedic professionals. The application features concise descriptions, images, videos, and statistical data, as well as direct links to relevant literature, all aimed at enhancing the quality of treatments and improving clinical outcomes.

Repisodic, Inc. is a healthcare technology company based in Philadelphia, Pennsylvania, focused on improving the transition of patients from hospitals to post-acute care settings, such as nursing homes and rehabilitation centers. Founded in 2017, Repisodic offers solutions that enhance care decision-making for patients, families, and caregivers. Its flagship products include Repisodic Choice, which helps hospitals and health systems create dynamic preferred provider networks tailored to individual patient needs, and Repisodic Link, designed for post-acute care providers to facilitate referrals and connect with patients. The platform utilizes proprietary data and automation to streamline the discharge process, allowing discharge planners to match patients with suitable post-discharge options based on factors like insurance networks and clinical capabilities. Overall, Repisodic aims to revolutionize how care decisions are made, ensuring that patients receive optimal post-hospital care.

ChromaTan Inc. specializes in developing continuous countercurrent tangential chromatography (CCTC) technology for the purification of monoclonal antibodies and proteins. The company's innovative platform addresses significant process bottlenecks in therapeutic protein production, offering a cost-effective, column-free, and continuous purification solution. This technology has undergone extensive beta testing with numerous leading biotech firms, demonstrating a 5-15 times increase in throughput while maintaining or improving product quality. Founded in 2007 and headquartered in Lower Gwynedd, Pennsylvania, ChromaTan aims to provide scalable and efficient alternatives to traditional large-scale column chromatography processes, thereby lowering production costs for biotechnology and contract manufacturing companies.

Excision BioTherapeutics Inc. is a life science company based in Philadelphia, Pennsylvania, established in 2015. The company specializes in developing gene editing therapeutics aimed at treating life-threatening diseases caused by neurotropic viruses. Utilizing CRISPR-based technology, Excision BioTherapeutics focuses on creating advanced gene-editing medicines that can eradicate or disrupt viral genes in human patients. The company is committed to advancing these therapeutics to ensure they are safe and effective, with the goal of significantly improving the lives of individuals affected by viral infections worldwide.

Cassian Solutions, Inc. is a company that develops innovative medication management solutions, including a phone case medication dispenser and a comprehensive application designed to enhance patient compliance. Founded in 2018 and based in Phoenixville, Pennsylvania, the company targets pharmacies, clinical trial organizations, drug manufacturers, and insurers. Its platform addresses critical issues in patient monitoring and data reporting within the specialty medication market, clinical trials, and healthcare systems, aiming to improve health outcomes and reduce healthcare costs. By leveraging the widespread use of smartphones, Cassian Solutions focuses on creating personalized patient journeys that enhance engagement and facilitate real-time communication among all stakeholders involved in medication management.

Open Medical Innovation is an organization founded by leaders from Archimedic, NextFab, and the University of Pennsylvania. We launched this organization with a focus on addressing the shortage of Personal Protective Equipment (PPE) during the COVID-19 outbreak. We intend to use this website to share information, collect feedback, and fulfill the unmet needs of patients and providers.

AAPlasma is developing a cold plasma-based system that is based on previously-successful technology capable of achieving in-between-patient decontamination of PPE items to allow for rapid reuse.

SFA Therapeutics, Inc. is a development-stage bio-pharmaceutical company located in Jenkintown, Pennsylvania. The company specializes in creating drugs derived from microbiome-derived metabolites aimed at treating chronic inflammatory diseases and cancer. By harnessing compounds discovered in the human microbiome, SFA Therapeutics seeks to provide innovative therapeutic solutions for various medical conditions, including autoimmune diseases and liver disorders.

Astarte Medical, established in 2016 and headquartered in Yardley, Pennsylvania, specializes in developing software for clinical intelligence. Its platform offers a real-time, comprehensive view of clinical data, focusing on the gut health of preterm infants in Neonatal Intensive Care Units (NICUs). By standardizing and streamlining feeding practices, Astarte Medical empowers clinical care teams to make more informed decisions, ultimately enhancing patient outcomes and optimizing care for vulnerable pediatric populations.

RoundTrip, Inc. operates a digital marketplace that facilitates non-emergency medical transportation by connecting patients with a network of ride providers. Founded in 2014 and based in Philadelphia, Pennsylvania, the company offers a user-friendly software platform that allows healthcare organizations and transportation companies to schedule, dispatch, and monitor patient rides. RoundTrip serves hospitals and health plans in ten states, aiming to improve care coordination and reduce patient no-shows. The platform provides access to various transportation options, including medical cars, wheelchair vans, and stretcher vehicles. RoundTrip has established strategic partnerships with notable healthcare organizations, enhancing its service offerings. The team behind RoundTrip consists of professionals with experience as paramedics and in healthcare management, which informs their approach to addressing the challenges in medical transportation.

MBF Therapeutics, Inc. is a veterinary oncology company that specializes in developing and commercializing innovative therapies for cancer treatment in dogs and cats. The company's product portfolio features targeted immunotherapies and small molecule drugs designed to disrupt tumor cell metabolism while sparing healthy tissues. Key products include MBFT-101, a combination therapy for sarcomas and lymphoma that utilizes a proprietary polyamine transport inhibitor alongside a potent inhibitor of ornithine decarboxylase, and MBFT-102, an immunotherapy based on the tumor suppressor/cytokine mda-7/IL24, which has shown promise in human clinical trials for various advanced cancers. Additionally, MBF Therapeutics is advancing a gene-based vaccine platform aimed at improving treatments for both cancer and infectious diseases in animals, with the potential to transform veterinary medicine. The company is located in Ambler, Pennsylvania, and maintains a strategic partnership with the Lankenau Institute for Medical Research.

RoundTrip, Inc. operates a digital marketplace that facilitates non-emergency medical transportation by connecting patients with a network of ride providers. Founded in 2014 and based in Philadelphia, Pennsylvania, the company offers a user-friendly software platform that allows healthcare organizations and transportation companies to schedule, dispatch, and monitor patient rides. RoundTrip serves hospitals and health plans in ten states, aiming to improve care coordination and reduce patient no-shows. The platform provides access to various transportation options, including medical cars, wheelchair vans, and stretcher vehicles. RoundTrip has established strategic partnerships with notable healthcare organizations, enhancing its service offerings. The team behind RoundTrip consists of professionals with experience as paramedics and in healthcare management, which informs their approach to addressing the challenges in medical transportation.

Keriton LLC is a provider of a pumped breast milk management system specifically designed for neonatal intensive care units (NICUs). Based in Philadelphia, Pennsylvania, the company offers a comprehensive platform that enhances patient safety and streamlines nursing workflows. This system enables healthcare professionals to track milk-bottle inventory, manage feeding orders, and handle first-in-first-out (FIFO) bottle flow, including notifications for expiry dates and misfeed alerts. The platform also facilitates real-time insights into lactating mothers' milk production patterns and includes a media-sharing feature for nurses to communicate with mothers by sharing photos and videos of their babies. With a track record of managing over 1.5 million feeds and preventing nearly 30,000 errors, Keriton's solution aims to improve health outcomes and reduce the cognitive burden on hospital staff. Since its incorporation in 2016, Keriton has been deployed in numerous larger enterprise health systems, demonstrating its effectiveness in enhancing the care provided to infants in NICUs.

GSI Health, LLC is a health information technology company that specializes in population health management through its cloud-based software solutions. Founded in 2003 and headquartered in Philadelphia, Pennsylvania, with an additional office in New York, the company provides tools for care coordination, care management, and health insights. GSI Health's platform is designed to enhance communication and information sharing among healthcare providers, including hospitals, health systems, managed care organizations, Medicaid programs, and community-based organizations. The solutions aim to improve transitions in care, reduce avoidable hospital readmissions, and support analytics and reporting for patient care. Additionally, the platform includes built-in Health Information Exchange (HIE) capabilities, facilitating seamless data sharing across organizational boundaries. As of October 2019, GSI Health operates as a subsidiary of Medecision, Inc.

Instadiagnostics Inc. develops a point-of-care (POC) diagnostic platform that aims to bring centralized laboratory testing directly to patients at their bedside. This innovative platform enables early diagnosis and treatment monitoring in various settings, including primary care centers, community clinics, and emergency departments. By eliminating the need for additional trips for blood tests and reducing lengthy wait times for results, Instadiagnostics enhances patient care and satisfaction. The company, incorporated in 2015 and based in Philadelphia, Pennsylvania, focuses on streamlining the diagnostic process, ultimately aiming to reduce the number of medical visits and overall healthcare costs.

Cagent Vascular, LLC is a medical device company based in Wayne, Pennsylvania, focused on developing innovative solutions for cardiovascular diseases. The company specializes in angioplasty balloons that utilize proprietary serration technology to enhance treatment outcomes. Its flagship product, the Serranator, features serrated metal strips embedded in a semi-compliant balloon, designed specifically for the treatment of atherosclerosis and conditions such as peripheral artery disease and chronic limb-threatening ischemia. By employing a minimally invasive approach, Cagent Vascular aims to improve vessel dilatation during cardiovascular interventions, ultimately enhancing patient care and quality of life. Founded in 2014, the company is dedicated to advancing intravascular technology in the medical field.

Ultraflex Systems specializes in designing and engineering custom Range of Motion (ROM) braces that enhance movement and promote active living. With over 25 years of experience, the company collaborates closely with physicians, physical therapists, and specialists to deliver innovative orthopedic and neurological solutions. Ultraflex Systems distinguishes itself through a dedicated direct care team, which includes sales professionals and certified orthotists or fitters. This team oversees the entire process from the physician's referral to brace delivery and subsequent patient follow-up. The company’s custom-molded braces are crafted in its fabrication facilities to ensure optimal fit and effectiveness, ultimately improving joint and limb motion and supporting the musculoskeletal system for better patient outcomes.

PolyCore Therapeutics is focused on developing innovative treatments for central nervous system (CNS) disorders, specifically targeting dyskinesia and cognitive impairment. The company aims to create new, affordable therapies that address the side effects associated with the treatment of Parkinson's disease and other neurological conditions. By enhancing patient mobility and quality of life, PolyCore Therapeutics seeks to contribute to more effective management of these disorders while also aiming to reduce overall healthcare costs. Their experienced team of scientists and life sciences professionals is dedicated to advancing research in this critical area of healthcare.

Essential Medical is a family owned & operated business that was started in 1985. We are a broad based supplier of home medical and health related products designed with the needs of the user in mind. Within this online website you will find many different product options to meet a variety of life styles and physical conditions. If you are a home medical equipment dealer and would like to be set up to order Essential products, please click on the Prospective Dealers tab. If you would like to purchase products for yourself, family member or friend, our fine products are available through your local medical equipment dealer or pharmacy. Please consult the yellow pages of your local telephone book under Hospital and Medical Equipment.

Instadiagnostics Inc. develops a point-of-care (POC) diagnostic platform that aims to bring centralized laboratory testing directly to patients at their bedside. This innovative platform enables early diagnosis and treatment monitoring in various settings, including primary care centers, community clinics, and emergency departments. By eliminating the need for additional trips for blood tests and reducing lengthy wait times for results, Instadiagnostics enhances patient care and satisfaction. The company, incorporated in 2015 and based in Philadelphia, Pennsylvania, focuses on streamlining the diagnostic process, ultimately aiming to reduce the number of medical visits and overall healthcare costs.

Allevi develops innovative tools for designing and engineering 3D tissues, focusing on bioprinting technology. The company offers desktop 3D bioprinters that allow users to create functional three-dimensional living tissues using various biomaterials and cell lines. Additionally, Allevi provides bioinks made from collagen and hyaluronic acid, which are available for purchase online. Their cloud-based platform, Bioprint Online, enables users to design complex structures, define materials, and monitor the printing process. Allevi's products serve a diverse clientele, including researchers in tissue engineering, regenerative medicine, and cell biology, as well as industrial and pharmaceutical companies for drug testing and development, and educators. Established in 2014 and based in Philadelphia, Pennsylvania, Allevi was formerly known as BioBots, Inc.

DecNut specializes in developing point-of-care technologies aimed at enhancing clinical decision-making across various healthcare settings. The company's tools integrate evidence-based clinical practice guidelines into the workflow of healthcare providers, facilitating improved resource utilization and patient care outcomes. By offering an application that allows professionals to easily aggregate, update, disseminate, and evaluate tailored clinical decision support, DecNut supports healthcare practitioners in making informed decisions, ultimately leading to more efficient and effective healthcare delivery.

Grand Round Table Inc. is a developer of clinical decision support tools aimed at enhancing diagnostic accuracy for healthcare providers. The company's flagship system, Grand Round Table, integrates with electronic health records to assist doctors in diagnosing patients by comparing their cases against a comprehensive database of deidentified health records, case reports, and evidence-based medical literature, including resources from the University of Pennsylvania. This technology enables physicians to access insights from previous cases, facilitating quicker and more informed treatment decisions for complex patients. By streamlining the decision-making process, Grand Round Table helps hospitals and clinics reduce unnecessary tests, ineffective treatments, and consultations, ultimately saving time and costs in patient care. Established in 2011, the company is headquartered in Philadelphia, Pennsylvania.

PrescribeWell, Inc. is a Hatfield, Pennsylvania-based company that offers a platform-as-a-service designed to assist healthcare providers in tracking and analyzing behavioral modifications, such as obesity treatment, smoking cessation, and stress management. The platform allows healthcare providers to seamlessly integrate its software solution into existing electronic medical records systems, creating a physician-centric hub that supports wellness regimens for patients while optimizing billing processes for providers. By facilitating effective patient-physician engagement and ongoing communication, PrescribeWell aims to enhance patient outcomes in health management, disease prevention, and lifestyle modifications. The company was incorporated in 2012.

Atrin Pharmaceuticals LLC is a biopharmaceutical company based in Doylestown, Pennsylvania, focused on the discovery and development of innovative cancer treatments. Founded in 2011, the company is developing its lead drug candidates, ATRN-502, a p53 activator, and ATRN-507, a dual ligand that selectively targets cancer cells. Atrin is also advancing a proprietary platform called Atrize, which utilizes phenotypic FACS-based screening for rapid identification of effective drug candidates and evaluation of personalized medicine approaches. The company's research aims to address cancers linked to synthetic lethality and deregulated DNA damage response, with a focus on creating treatments that are effective against cancer cells while minimizing impact on healthy cells. Through its innovative methodologies, Atrin Pharmaceuticals seeks to change the landscape of cancer therapy.

Prescription Advisory Systems & Technology, Inc. is dedicated to enhancing the management of chronic pain and mitigating the risks associated with the abuse of controlled substances through its innovative software, PASTRx. Established in 2013 and based in Jenkintown, Pennsylvania, the company addresses the critical issue of prescription medication overdoses, which have become the leading cause of accidental death in the United States. PASTRx is designed to assist healthcare providers in identifying patients who can safely receive controlled substances while flagging those who may need more complex treatment options. The software integrates data from multiple sources, offering features such as patient risk assessment, auditability, and institutional oversight, all within a user-friendly interface. This comprehensive approach aims to protect both patients and healthcare providers, ensuring safer prescribing practices.

Essential Medical is a family owned & operated business that was started in 1985. We are a broad based supplier of home medical and health related products designed with the needs of the user in mind. Within this online website you will find many different product options to meet a variety of life styles and physical conditions. If you are a home medical equipment dealer and would like to be set up to order Essential products, please click on the Prospective Dealers tab. If you would like to purchase products for yourself, family member or friend, our fine products are available through your local medical equipment dealer or pharmacy. Please consult the yellow pages of your local telephone book under Hospital and Medical Equipment.

Allevi develops innovative tools for designing and engineering 3D tissues, focusing on bioprinting technology. The company offers desktop 3D bioprinters that allow users to create functional three-dimensional living tissues using various biomaterials and cell lines. Additionally, Allevi provides bioinks made from collagen and hyaluronic acid, which are available for purchase online. Their cloud-based platform, Bioprint Online, enables users to design complex structures, define materials, and monitor the printing process. Allevi's products serve a diverse clientele, including researchers in tissue engineering, regenerative medicine, and cell biology, as well as industrial and pharmaceutical companies for drug testing and development, and educators. Established in 2014 and based in Philadelphia, Pennsylvania, Allevi was formerly known as BioBots, Inc.

Advent Therapeutics is a pharmaceutical company based in Lumberville, Pennsylvania, dedicated to developing therapies for micro-orphan applications, specifically targeting serious unmet medical needs in neonatal and pediatric populations. The company focuses on legacy drugs aimed at treating disorders in newborn infants, particularly those in intensive care units. By creating prenatal, neonatal, and pediatric medications, Advent Therapeutics enables healthcare professionals to provide advanced care for vulnerable patients, addressing critical gaps in existing treatment options for this underserved demographic.

Vy Corporation is a software development company based in Wayne, Pennsylvania, that specializes in shape detection and object analysis software for the medical imaging market. The company offers CytoSavvy.com, a cloud-based image analysis and data collection service that enables users to upload and analyze images, particularly useful for identifying clusters of cells in liver and kidney biopsies using its patented CellQuant™ search technology. In addition, Vy Corporation provides VectorSavvy.com, which grants users access to advanced image analysis tools for loading images and viewing results, and it also develops custom projects tailored to specific client needs. The company's mission is to assist pathologists and medical researchers in efficiently identifying and analyzing complex cell structures, enhancing the reliability of data for research and diagnostics.

Grand Round Table Inc. is a developer of clinical decision support tools aimed at enhancing diagnostic accuracy for healthcare providers. The company's flagship system, Grand Round Table, integrates with electronic health records to assist doctors in diagnosing patients by comparing their cases against a comprehensive database of deidentified health records, case reports, and evidence-based medical literature, including resources from the University of Pennsylvania. This technology enables physicians to access insights from previous cases, facilitating quicker and more informed treatment decisions for complex patients. By streamlining the decision-making process, Grand Round Table helps hospitals and clinics reduce unnecessary tests, ineffective treatments, and consultations, ultimately saving time and costs in patient care. Established in 2011, the company is headquartered in Philadelphia, Pennsylvania.

Essential Medical is a family owned & operated business that was started in 1985. We are a broad based supplier of home medical and health related products designed with the needs of the user in mind. Within this online website you will find many different product options to meet a variety of life styles and physical conditions. If you are a home medical equipment dealer and would like to be set up to order Essential products, please click on the Prospective Dealers tab. If you would like to purchase products for yourself, family member or friend, our fine products are available through your local medical equipment dealer or pharmacy. Please consult the yellow pages of your local telephone book under Hospital and Medical Equipment.

BioDetego is focused on advancing cancer treatment through its innovative biomarker test, VASPfore, which is designed to optimize the selection of chemotherapy protocols. This test assesses the metastatic risk in colorectal cancer patients, allowing healthcare providers to identify high-risk individuals who are likely to benefit from chemotherapy while sparing low-risk patients from unnecessary and potentially harmful treatments. By providing actionable insights, VASPfore aims to improve patient outcomes and enhance the efficiency of cancer management. BioDetego anticipates significant cost savings for payors, estimating reductions of over $150 million annually in treatment expenses. The company is led by David Zuzga, Ph.D., and Giovanni M. Pitari, M.D., Ph.D., both of whom bring extensive expertise in cell and molecular biology and translational oncology, respectively.

Relmada Therapeutics, Inc. is a clinical-stage biotechnology company based in New York, focused on developing innovative treatments for central nervous system (CNS) diseases. Established in 2004, the company is primarily working on its lead product candidate, d-Methadone, which is undergoing Phase II clinical trials for conditions such as major depressive disorder and neuropathic pain. In addition to d-Methadone, Relmada is developing LevoCap ER, a sustained-release formulation of levorphanol designed to be abuse-resistant; BuTab, an oral formulation of buprenorphine; and MepiGel, a topical formulation of mepivacaine intended for localized anesthesia. The company's research aims to address significant unmet medical needs in CNS disorders and improve patient outcomes.

CD Diagnostics is developing assays for orthopaedic surgeons and rheumatologists who would like greater diagnostic confidence in joint fluid analysis. Unlike current technologies, which often yield vague and ambiguous results, CygnaSure™, our lead product, offers orthopaedic surgeons and rheumatologists a rapid, accurate and reliable diagnostic answer.

Prezacor, Inc. specializes in developing and marketing innovative pain management solutions, with its primary product being the Energeze™ Patch. This patch utilizes the company's proprietary Energezics™ technology, designed to alleviate both acute and chronic pain without the use of medication. It features a unique broad-area surface electrode made from a specialized formula that absorbs and resonates with a variety of naturally occurring waveforms present in living tissues. By delivering these waveforms, the patch aims to reduce pain and discomfort across multiple areas of the body, providing a non-invasive alternative for pain relief.

EyeIC, Inc. is a medical technology company focused on developing and commercializing imaging technologies for eye care applications. Based in Wayne, Pennsylvania, EyeIC serves eye care professionals and clinics by offering the MatchedFlicker device, which monitors the onset and progression of glaucoma through change detection in time series retinal photographs. The technology aligns and registers images taken at different times, creating a superimposed view that aids in accurate diagnosis. Additionally, EyeIC's software includes an easy-to-use application that streamlines image processing, interpretation, and reporting, facilitating the detection of various retinal conditions such as diabetic retinopathy and retinopathy of prematurity. Established in 2004, EyeIC aims to simplify workflows for clinicians and enhance patient care in the field of ophthalmology.

Real Time Tomography, LLC specializes in developing advanced imaging software solutions for medical imaging systems, particularly in the field of breast cancer detection. Founded in 2006 and based in Villanova, Pennsylvania, the company offers two primary products: Adara, which enhances digital mammography images to improve tissue contrast and lesion visibility, and Briona, a software that reconstructs 3D images from 2D tomosynthesis data. In addition to its software offerings, Real Time Tomography provides technical support and consultation services aimed at optimizing detector and system design for enhanced image quality and processing speed. The company primarily serves manufacturers of mammography systems and PACS workstations, contributing to improved diagnostic accuracy and clinical workflows in healthcare settings.

Essential Medical is a family owned & operated business that was started in 1985. We are a broad based supplier of home medical and health related products designed with the needs of the user in mind. Within this online website you will find many different product options to meet a variety of life styles and physical conditions. If you are a home medical equipment dealer and would like to be set up to order Essential products, please click on the Prospective Dealers tab. If you would like to purchase products for yourself, family member or friend, our fine products are available through your local medical equipment dealer or pharmacy. Please consult the yellow pages of your local telephone book under Hospital and Medical Equipment.

Essential Medical is a family owned & operated business that was started in 1985. We are a broad based supplier of home medical and health related products designed with the needs of the user in mind. Within this online website you will find many different product options to meet a variety of life styles and physical conditions. If you are a home medical equipment dealer and would like to be set up to order Essential products, please click on the Prospective Dealers tab. If you would like to purchase products for yourself, family member or friend, our fine products are available through your local medical equipment dealer or pharmacy. Please consult the yellow pages of your local telephone book under Hospital and Medical Equipment.

Ceptaris Therapeutics, Inc. is a privately held specialty pharmaceutical company focused on developing a proprietary gel formulation of mechlorethamine hydrochloride for treating early-stage (stages I-IIA) mycosis fungoides, a form of Cutaneous T-Cell Lymphoma (CTCL). If approved, this investigational drug would be the first topical mechlorethamine product available for managing the signs and symptoms of this rare cancer. In addition to this primary focus, Ceptaris is also involved in developing other therapeutic products, including YT-1006, an NMDA antagonist aimed at treating neuropathic pain while minimizing side effects associated with NMDA. The company's innovative approaches enable healthcare professionals to address both dermatological and central nervous system disorders effectively.

Bionano Genomics, Inc. is a biotechnology company focused on genome mapping and analysis. It develops and markets the Saphyr system, an advanced platform designed for ultra-sensitive and specific detection of structural variations in DNA, such as insertions, deletions, and translocations, which are often linked to genetic disorders and diseases, including cancer. The Saphyr system employs optical genome mapping technology, allowing for direct visualization and analysis of long DNA molecules without relying on sequencing. This capability provides researchers and clinicians with critical insights into the structural variations within genomes, enhancing the understanding of disease mechanisms and supporting the development of personalized treatment strategies. Bionano Genomics also offers essential reagents and data solutions, including Bionano prep kits, labeling kits, and software tools for comprehensive experiment management. Its products are primarily sold to academic and governmental research laboratories, as well as pharmaceutical, biotechnology, and contract research organizations across multiple regions, including North America, Europe, and Asia. Founded in 2003 and headquartered in San Diego, California, the company was previously known as BioNano Genomics, Inc. until its name change in July 2018.

Acuity Pharmaceuticals is a pharmaceutical company based in Philadelphia, Pennsylvania, established in 2007. It specializes in the treatment and prevention of ophthalmic diseases, particularly focusing on age-related macular degeneration (AMD) and diabetic retinopathy (DR). The company is developing small interfering RNA compounds aimed at addressing vision loss associated with these conditions. One of its key products, Cand5, is a clinical compound designed to inhibit vascular endothelial growth factor, thereby targeting adult vision loss. In June 2011, Acuity Pharmaceuticals was acquired by OPKO Health, enhancing its capabilities in the ophthalmic market.

SFA Therapeutics, Inc. is a development-stage bio-pharmaceutical company located in Jenkintown, Pennsylvania. The company specializes in creating drugs derived from microbiome-derived metabolites aimed at treating chronic inflammatory diseases and cancer. By harnessing compounds discovered in the human microbiome, SFA Therapeutics seeks to provide innovative therapeutic solutions for various medical conditions, including autoimmune diseases and liver disorders.