Ben Franklin Technology Partners of Southeastern Pennsylvania

Ben Franklin Technology Partners of Southeastern Pennsylvania, established in 1982 and based in Philadelphia, is a prominent capital provider dedicated to the technology sectors within Pennsylvania. The organization specializes in both early-stage and established companies, with a focus on enhancing the region's innovation ecosystem across information technology, health, and physical sciences. Over its 30-year history, Ben Franklin has invested in more than 2,000 technology companies and has contributed over $170 million to drive regional growth. In addition to its investment activities, Ben Franklin fosters university and industry partnerships to facilitate the commercialization of scientific discoveries, while also supporting initiatives that bolster the local entrepreneurial community.

Jonathan Beschen

Investment Director, Information Technology Investment Group

Anthony George

Venture Capital Associate, Tech Investment Group

Jennifer Hartt

Director of Investments

Omar Mencin

Senior Director of Investments, Investment Group

Kathie Jordan Ph.D

Managing Director, Healthcare Investment Group

Past deals in Eastern US

CollX

Series A in 2025
CollX, founded in 2021 and based in Haddonfield, New Jersey, offers a financial application that allows users to quickly determine the market value of sports cards by simply snapping photos of them. Utilizing advanced technology, the app identifies cards and provides instant pricing information. In addition to valuation, CollX facilitates a marketplace where collectors can buy and sell collectibles with transparency regarding the counterparty's collection. Users have the ability to add cards to their collections, follow other collectors, and engage in trading, including the creation of ad-hoc lots for transactions.

Avisi Technologies

Seed Round in 2022
Avisi Technologies Inc. is a company based in Philadelphia, Pennsylvania, that focuses on developing innovative solutions for glaucoma treatment. Founded in 2017, the company has created VisiPlate, a next-generation aqueous shunt that utilizes nanotechnology to provide a defense against blindness caused by glaucoma. This advanced technology aims to improve the effectiveness of glaucoma treatments and enhance patient outcomes.

GrowFlux

Pre Seed Round in 2022
GrowFlux, Inc. specializes in developing advanced lighting and sensing solutions for greenhouses, vertical farms, and cannabis producers. Founded in 2014 and based in Philadelphia, the company offers a range of products, including the FluxScale Top Light and GrowFlux Dimmer, which enhance control and connectivity in horticultural lighting. Additionally, GrowFlux provides turnkey sensing packages for monitoring environmental conditions in indoor cannabis facilities, ensuring optimal operation of energy-intensive climate control systems and preventing disease. Their platform incorporates IoT control and automation technologies, which help modernize agricultural practices and achieve significant cost and energy savings. The company also operates a cloud software application for managing lighting schedules and spectrum settings tailored to specific crop outcomes, thereby supporting growers and equipment manufacturers in maintaining competitiveness in a dynamic industry.

Yellowdig

Venture Round in 2022
Yellowdig is a software platform that enhances peer learning outcomes by creating a social layer on top of existing enterprise learning systems utilized by colleges, universities, and organizations. Established in 2015 and based in Philadelphia, Pennsylvania, Yellowdig focuses on providing a private and secure experience tailored for higher education institutions. The platform fosters collaborative learning environments, encouraging student engagement and retention while enhancing their understanding of current affairs. By integrating with established learning systems, Yellowdig transforms traditional classrooms into vibrant learning communities.

Nia Therapeutics

Venture Round in 2021
Nia Therapeutics, Inc. is a company focused on developing precision neurostimulation therapies aimed at treating memory impairment, particularly in patients with traumatic brain injury. Founded in 2016, Nia Therapeutics is based in Radnor, Pennsylvania. The company's innovative approach involves utilizing neurostimulation devices that interpret complex brain activity related to memory function. By providing personalized therapy through deep-brain stimulation, Nia Therapeutics aims to enhance memory restoration and improve cognitive outcomes for affected individuals.

Avisi Technologies

Seed Round in 2021
Avisi Technologies Inc. is a company based in Philadelphia, Pennsylvania, that focuses on developing innovative solutions for glaucoma treatment. Founded in 2017, the company has created VisiPlate, a next-generation aqueous shunt that utilizes nanotechnology to provide a defense against blindness caused by glaucoma. This advanced technology aims to improve the effectiveness of glaucoma treatments and enhance patient outcomes.

Deepwave Digital

Seed Round in 2020
Deepwave Digital, Inc. specializes in manufacturing artificial intelligence (AI)-based hardware and software solutions tailored for radio frequency (RF) and wireless systems. Established in 2017 and headquartered in Philadelphia, Pennsylvania, the company provides integrated solutions that enhance the capabilities of RF systems by relocating the AI computation engine closer to the signal edge. This innovative approach minimizes network bandwidth usage, reduces latency, and decreases reliance on manual analysis. Deepwave Digital's product lineup includes the Artificial Intelligence Radio Transceiver (AIR-T), a software-defined radio, as well as software tools like AirPack, AirStack Sandbox, and Spectrum Sensing, which help clients detect and identify signals in their spectral environment. With a team of RF industry experts boasting over fifty years of combined experience, Deepwave Digital serves both commercial and defense sectors, enabling customers to develop custom AI and high-performance computing systems using trusted software solutions.

DrayNow

Series A in 2020
DrayNow, Inc. is a technology company based in Pipersville, Pennsylvania, founded in 2017. It operates a real-time marketplace designed specifically for intermodal trucking, connecting freight with carriers efficiently. This platform allows intermediaries to engage with more carriers, ensuring constant visibility of shipment locations and statuses. Additionally, it facilitates truckers in comparing rates, reviewing load details, and selecting available loads in their vicinity in real-time. By leveraging advanced technology, DrayNow enhances operational efficiency for companies within the intermodal industry, helping them achieve optimal capacity, service levels, visibility, and profitability.

OsciFlex

Debt Financing in 2020
OsciFlex LLC, founded in 2017 and based in Philadelphia, Pennsylvania, specializes in developing a wearable medical device aimed at preventing blood clots in patients. The device functions by stimulating calf muscle contractions through a muscle stretch reflex, which promotes valve sinus recirculatory flow. This innovative approach helps to prevent venous thromboembolism (VTE), a serious condition that can lead to significant health complications. By offering an alternative to traditional anti-coagulation pharmaceuticals, which can be costly and carry risks, OsciFlex aims to enhance patient care and reduce healthcare costs associated with blood clot management.

Excision BioTherapeutics

Debt Financing in 2020
Excision BioTherapeutics Inc. is a life science company based in Philadelphia, Pennsylvania, established in 2015. The company specializes in developing gene editing therapeutics aimed at treating life-threatening diseases caused by neurotropic viruses. Utilizing CRISPR-based technology, Excision BioTherapeutics focuses on creating advanced gene-editing medicines that can eradicate or disrupt viral genes in human patients. The company is committed to advancing these therapeutics to ensure they are safe and effective, with the goal of significantly improving the lives of individuals affected by viral infections worldwide.

Exyn

Debt Financing in 2020
Exyn Technologies, Inc. is a company focused on developing autonomous aerial robots designed for complex commercial environments. Established in 2014 as a spin-off from the GRASP Laboratory at the University of Pennsylvania, Exyn leverages over a decade of research in autonomous flight and aerial robotics. The company's flagship product, exynAI, is a modular software system that enables pilot-less flights and facilitates communication between multiple flying vehicles. Exyn's drones utilize a unique technology that integrates multiple redundant sensors, advanced mapping for obstacle avoidance, and autonomous flight planning, making them suitable for applications such as underground inspections, inventory management, and construction documentation. With their robust and highly differentiated capabilities, Exyn's aerial robots provide clients with the ability to automate dangerous tasks and address various complex operational challenges. The company is headquartered in Philadelphia, Pennsylvania.

LeagueSide

Debt Financing in 2020
LeagueSide, Inc. is a youth sports marketing company that connects regional and national brands with families involved in youth sports through its online platform. This platform allows youth sports leagues to join the LeagueSide network, facilitating sponsorship opportunities that range from branding on jerseys to promotional tables at events and sweepstakes. Brands can select from various youth sports leagues based on demographics and geographical reach, enabling them to engage with families during meaningful moments. Additionally, LeagueSide offers resources for entrepreneurs, including campaign management support and performance reporting. Founded in 2015 and headquartered in Philadelphia, Pennsylvania, LeagueSide is recognized as a leading community sports sponsorship platform, making sponsorships scalable and measurable.

Kognition

Debt Financing in 2020
Kognition LLC specializes in developing enterprise software solutions for real estate property managers and security operators. Founded in 2017 and based in Philadelphia, Pennsylvania, the company's platform employs artificial intelligence and machine learning to create a responsive environment for buildings, addressing security, property activities, surveillance, logistics, environmental, and maintenance challenges. Kognition's flagship product, the SuperGuard solution, integrates live security camera footage with sensor data to identify and mitigate security threats. The platform is designed to provide enhanced safety and security for a wide range of sectors, including healthcare, financial services, and commercial real estate, by generating real-time alerts to prevent various high-impact dangers. By connecting cameras, sensors, and smart devices into a cohesive system, Kognition aims to minimize false alarms and proactively manage security and compliance operations.

Switchboard Live

Convertible Note in 2020
Switchboard Live Inc. operates a live video streaming and syndication platform designed to connect brands and advertisers with targeted audiences across various online channels. Founded in 2014 and based in Philadelphia, Pennsylvania, the company facilitates the management of multiple live streams through a unified dashboard, allowing content creators to efficiently distribute live videos to social media platforms and web pages. Its offerings include the Producer solution, which tailors audience access based on budget and demographic targets, as well as Joicaster, a stream-sharing tool that consolidates live chats into a cohesive cross-platform experience. Serving a diverse range of sectors such as entertainment, government, gaming, and sports, Switchboard Live aims to enhance audience engagement and boost subscriptions for its clients. The company was previously known as Joicaster Inc. before rebranding in February 2016.

Yellowdig

Venture Round in 2020
Yellowdig is a software platform that enhances peer learning outcomes by creating a social layer on top of existing enterprise learning systems utilized by colleges, universities, and organizations. Established in 2015 and based in Philadelphia, Pennsylvania, Yellowdig focuses on providing a private and secure experience tailored for higher education institutions. The platform fosters collaborative learning environments, encouraging student engagement and retention while enhancing their understanding of current affairs. By integrating with established learning systems, Yellowdig transforms traditional classrooms into vibrant learning communities.

Guiding Technologies

Grant in 2020
Guiding Technologies is a Philadelphia-based start-up dedicated to helping individuals with autism reach their full potential. Our product, GAINS™, is the first haptic feedback guidance and analysis software program designed exclusively for Applied Behavioral Analysis instruction management. GAINS™ guides and track ABA instruction in real-time with unprecedented detail and ease. It records each activity or trial with tactile input and unobtrusive audio response, avoiding any client distraction. The haptic feedback and seamless program-to-program transitions allow staff to focus on client instruction. Bulky program binders are consolidated into a tablet computer, and after-session reports can include detailed real-time performance data. GAINS™ automatically retrieves and evaluates client progress and staff management reporting with clearly designed charts and graphs – allowing you to maximize the performance of your organization.

SFA Therapeutics

Grant in 2020
SFA Therapeutics, Inc. is a development-stage bio-pharmaceutical company located in Jenkintown, Pennsylvania. The company specializes in creating drugs derived from microbiome-derived metabolites aimed at treating chronic inflammatory diseases and cancer. By harnessing compounds discovered in the human microbiome, SFA Therapeutics seeks to provide innovative therapeutic solutions for various medical conditions, including autoimmune diseases and liver disorders.

Boostpoint

Pre Seed Round in 2020
Boostpoint, LLC, founded in 2018 and based in Lancaster, Pennsylvania, specializes in developing a software-as-a-service mobile application and online platform for digital advertising and talent acquisition. The platform enables local brands, such as contractors, cafes, and real estate professionals, to create, target, publish, and measure digital advertisement campaigns, thereby enhancing their brand presence and driving local business. Additionally, Boostpoint provides recruitment marketing solutions that help talent acquisition teams capture qualified leads and streamline hiring processes. This is achieved through a combination of a social media recruiting platform, text message automation tools, and an AI writing assistant, which collectively facilitate the automation of the job hiring process.

Navrogen

Convertible Note in 2019
Navrogen, Inc. is a biopharmaceutical company based in Philadelphia, Pennsylvania, founded in 2017. The company specializes in the targeted treatment of cancer by enhancing the immune system's ability to combat tumors. Navrogen develops technology that identifies proteins produced by tumors that suppress the body's humoral immune response, which can hinder both natural immunity and the effectiveness of antibody-based therapies. By assembling a comprehensive database of tumor types that produce these immunosuppressive factors, Navrogen aims to support physicians in overcoming these challenges, thereby improving cancer treatment outcomes.

Deepwave Digital

Seed Round in 2019
Deepwave Digital, Inc. specializes in manufacturing artificial intelligence (AI)-based hardware and software solutions tailored for radio frequency (RF) and wireless systems. Established in 2017 and headquartered in Philadelphia, Pennsylvania, the company provides integrated solutions that enhance the capabilities of RF systems by relocating the AI computation engine closer to the signal edge. This innovative approach minimizes network bandwidth usage, reduces latency, and decreases reliance on manual analysis. Deepwave Digital's product lineup includes the Artificial Intelligence Radio Transceiver (AIR-T), a software-defined radio, as well as software tools like AirPack, AirStack Sandbox, and Spectrum Sensing, which help clients detect and identify signals in their spectral environment. With a team of RF industry experts boasting over fifty years of combined experience, Deepwave Digital serves both commercial and defense sectors, enabling customers to develop custom AI and high-performance computing systems using trusted software solutions.

Tridiuum

Series B in 2018
Tridiuum, Inc. is a Philadelphia-based digital health company established in 1997 that specializes in software-as-a-service solutions for behavioral health providers, patients, and health systems. The core offering, Tridiuum1, is a cloud-based platform designed to enhance behavioral health outcomes management by monitoring patient symptoms and treatment progress. It integrates digital health assessments with an analytics engine to identify behavioral health issues, assign risk scores, and provide real-time alerts at the point of care. Additionally, the platform supports video-based virtual visits and other features, enabling clinicians to effectively evaluate and manage patients with various conditions. The company is backed by a team of experts in behavioral medicine and digital health technologies, with a strong foundation in clinical research and a history of contributions to peer-reviewed scientific literature.

Wearwell

Pre Seed Round in 2018
Wearwell LLC, founded in 2015 and based in Philadelphia, Pennsylvania, operates an online subscription service that specializes in women’s apparel. The company caters to the growing market of conscious consumers, who prioritize ethical fashion and sustainability. Wearwell’s membership model allows customers to access clothing and accessories that align with their personal style while ensuring that the garments are produced under fair labor conditions and with consideration for environmental impact. By streamlining the shopping experience, Wearwell addresses the challenges faced by consumers in finding ethically made clothing, positioning itself as a leader in the ethical fashion space. The company's user base has been growing organically at a rate of 20% month-over-month, reflecting the increasing demand for sustainable and responsibly made fashion.

Deepwave Digital

Seed Round in 2018
Deepwave Digital, Inc. specializes in manufacturing artificial intelligence (AI)-based hardware and software solutions tailored for radio frequency (RF) and wireless systems. Established in 2017 and headquartered in Philadelphia, Pennsylvania, the company provides integrated solutions that enhance the capabilities of RF systems by relocating the AI computation engine closer to the signal edge. This innovative approach minimizes network bandwidth usage, reduces latency, and decreases reliance on manual analysis. Deepwave Digital's product lineup includes the Artificial Intelligence Radio Transceiver (AIR-T), a software-defined radio, as well as software tools like AirPack, AirStack Sandbox, and Spectrum Sensing, which help clients detect and identify signals in their spectral environment. With a team of RF industry experts boasting over fifty years of combined experience, Deepwave Digital serves both commercial and defense sectors, enabling customers to develop custom AI and high-performance computing systems using trusted software solutions.

Blogger Republik

Seed Round in 2018
Blogger Republik LLC, based in Wayne, Pennsylvania, was established in 2017 and specializes in creating and managing e-commerce platforms for influencers across various sectors, including beauty, lifestyle, gaming, and sports. The company provides a comprehensive suite of services, including e-commerce engine development, payment processing, product sourcing, fulfillment, shipping, and analytics reporting. Blogger Republik's platform empowers influencers to design and promote their own self-branded and unbranded subscription boxes, enabling them to effectively sell products directly to their social media followers.

MBF Therapeutics

Seed Round in 2018
MBF Therapeutics, Inc. is a veterinary oncology company that specializes in developing and commercializing innovative therapies for cancer treatment in dogs and cats. The company's product portfolio features targeted immunotherapies and small molecule drugs designed to disrupt tumor cell metabolism while sparing healthy tissues. Key products include MBFT-101, a combination therapy for sarcomas and lymphoma that utilizes a proprietary polyamine transport inhibitor alongside a potent inhibitor of ornithine decarboxylase, and MBFT-102, an immunotherapy based on the tumor suppressor/cytokine mda-7/IL24, which has shown promise in human clinical trials for various advanced cancers. Additionally, MBF Therapeutics is advancing a gene-based vaccine platform aimed at improving treatments for both cancer and infectious diseases in animals, with the potential to transform veterinary medicine. The company is located in Ambler, Pennsylvania, and maintains a strategic partnership with the Lankenau Institute for Medical Research.

Switchboard Live

Seed Round in 2017
Switchboard Live Inc. operates a live video streaming and syndication platform designed to connect brands and advertisers with targeted audiences across various online channels. Founded in 2014 and based in Philadelphia, Pennsylvania, the company facilitates the management of multiple live streams through a unified dashboard, allowing content creators to efficiently distribute live videos to social media platforms and web pages. Its offerings include the Producer solution, which tailors audience access based on budget and demographic targets, as well as Joicaster, a stream-sharing tool that consolidates live chats into a cohesive cross-platform experience. Serving a diverse range of sectors such as entertainment, government, gaming, and sports, Switchboard Live aims to enhance audience engagement and boost subscriptions for its clients. The company was previously known as Joicaster Inc. before rebranding in February 2016.

Mydealeronline

Convertible Note in 2017
MyDealerOnline, LLC provides a digital platform that enables car dealers to seamlessly broker wholesale auto auction inventory through their websites. This innovative technology allows dealers to access and display auction listings in real time, which helps them purchase the right vehicles at optimal prices while minimizing inventory costs and risks. By aggregating listings from various wholesale sources, including car auctions and rental companies, MyDealerOnline allows dealers to sell vehicles before acquiring them, thereby enhancing profit margins and saving time. The company serves a diverse clientele, including dealers, auctions, consignors, and consumers, and is headquartered in Langhorne, Pennsylvania.

Keriton

Seed Round in 2017
Keriton LLC is a provider of a pumped breast milk management system specifically designed for neonatal intensive care units (NICUs). Based in Philadelphia, Pennsylvania, the company offers a comprehensive platform that enhances patient safety and streamlines nursing workflows. This system enables healthcare professionals to track milk-bottle inventory, manage feeding orders, and handle first-in-first-out (FIFO) bottle flow, including notifications for expiry dates and misfeed alerts. The platform also facilitates real-time insights into lactating mothers' milk production patterns and includes a media-sharing feature for nurses to communicate with mothers by sharing photos and videos of their babies. With a track record of managing over 1.5 million feeds and preventing nearly 30,000 errors, Keriton's solution aims to improve health outcomes and reduce the cognitive burden on hospital staff. Since its incorporation in 2016, Keriton has been deployed in numerous larger enterprise health systems, demonstrating its effectiveness in enhancing the care provided to infants in NICUs.

Binto

Seed Round in 2016
Binto LLC, established in 2015 and based in Philadelphia, Pennsylvania, specializes in creating health supplements aimed at supporting women's reproductive health. The company offers a range of products, including fertility and women's health supplements, as well as organic period products such as tampons. Binto designs supplement kits tailored for women of all ages, utilizing natural and effective ingredients that are gluten-free, vegan-friendly, and free from preservatives and fillers. Each supplement is formulated with methylated folate, focusing on preventative care to enhance women's health from menstruation to menopause. Binto also provides access to licensed healthcare professionals, ensuring that women receive safe and effective over-the-counter products at affordable prices.

AuDIGENT

Venture Round in 2016
AuDIGENT is an audience intelligence platform that delivers actionable data, analytics, and insights to enhance the targeting and effectiveness of online and social video advertising. By enabling brands to discover and monitor key audiences, AuDIGENT helps optimize media performance and drive return on investment. The platform also empowers artists and social influencers by providing tools and technology to monetize their influence and engage with their fan base more effectively. With a presence in New York, Philadelphia, and London, AuDIGENT aims to create new revenue streams for influencers while improving advertising strategies for brands.

CyberCrunch

Seed Round in 2016
CyberCrunch specializes in data destruction and e-waste disposal solutions, offering comprehensive recycling services for a wide range of electronic equipment, including computers, monitors, networking devices, and batteries. The company provides secure destruction services such as on-site and off-site shredding, magnetic degaussing, and low-level wiping, ensuring permanent data destruction. Additionally, CyberCrunch offers IT consulting services for businesses undergoing workstation replacements, office relocations, and asset management. The company serves various sectors, including healthcare, financial services, education, and small businesses. Founded in 2010 in Greensburg, Pennsylvania, CyberCrunch was formerly known as Commonwealth Computer Recycling, LLC before rebranding in February 2017.

LeagueSide

Seed Round in 2016
LeagueSide, Inc. is a youth sports marketing company that connects regional and national brands with families involved in youth sports through its online platform. This platform allows youth sports leagues to join the LeagueSide network, facilitating sponsorship opportunities that range from branding on jerseys to promotional tables at events and sweepstakes. Brands can select from various youth sports leagues based on demographics and geographical reach, enabling them to engage with families during meaningful moments. Additionally, LeagueSide offers resources for entrepreneurs, including campaign management support and performance reporting. Founded in 2015 and headquartered in Philadelphia, Pennsylvania, LeagueSide is recognized as a leading community sports sponsorship platform, making sponsorships scalable and measurable.

Byndr

Seed Round in 2016
Byndr, Inc. is a mobile learning platform based in Philadelphia, Pennsylvania, that connects students, teachers, and colleges in the United States and India. Founded in 2015, the platform facilitates educational engagement by allowing teachers to manage subjects, post assignments, enter grades, and take attendance, while enabling students to access resources, track assignments, and interact with course content. Byndr emphasizes the creation of micro-lessons and encourages collaboration through a variety of free educational tools. Its goal is to simplify and enhance the learning experience by integrating content, context, and communication, making education both effective and enjoyable.

Cagent Vascular

Seed Round in 2016
Cagent Vascular, LLC is a medical device company based in Wayne, Pennsylvania, focused on developing innovative solutions for cardiovascular diseases. The company specializes in angioplasty balloons that utilize proprietary serration technology to enhance treatment outcomes. Its flagship product, the Serranator, features serrated metal strips embedded in a semi-compliant balloon, designed specifically for the treatment of atherosclerosis and conditions such as peripheral artery disease and chronic limb-threatening ischemia. By employing a minimally invasive approach, Cagent Vascular aims to improve vessel dilatation during cardiovascular interventions, ultimately enhancing patient care and quality of life. Founded in 2014, the company is dedicated to advancing intravascular technology in the medical field.

KickUp

Seed Round in 2016
KickUp helps professional development teams differentiate teacher support through analytics. Its SaaS-based analytics platform is designed to offer professional learning services. The analytics platform helps users customize pre-loaded goals to align with their district or region's strategic goals, pull together real-time data from surveys. They partner with K-12 organizations to coordinate professional learning efforts, improve decision-making, and ensure that great ideas translate into demonstrable outcomes in the classroom. Jeremy Rogoff, Victoria Kinzig, and Eric Krupski headquartered KickUp in Philadelphia, Pennsylvania in 2014.

Livegenic

Seed Round in 2016
Livegenic provides enterprise technology services and a virtual collaboration platform for insurance. The company connects every part of the claims ecosystem to help insurance organizations reduce costs, improve customer satisfaction, and mitigate business-related risk. Its cloud-based platform includes an app and browser-based solutions for real-time video collaboration, field documentation, and customer self-service that enables live video collaboration between an in-house adjuster, appraiser, and the policyholder, all without disconnecting the call. Livegenic also provides a suite of mobile solutions for insurance professionals that enable adjusters and inspectors to capture live and offline pictures and videos. Founded in 2014, LiveGenic is headquartered in Philadelphia, Pennsylvania.

Instadiagnostics

Seed Round in 2016
Instadiagnostics Inc. develops a point-of-care (POC) diagnostic platform that aims to bring centralized laboratory testing directly to patients at their bedside. This innovative platform enables early diagnosis and treatment monitoring in various settings, including primary care centers, community clinics, and emergency departments. By eliminating the need for additional trips for blood tests and reducing lengthy wait times for results, Instadiagnostics enhances patient care and satisfaction. The company, incorporated in 2015 and based in Philadelphia, Pennsylvania, focuses on streamlining the diagnostic process, ultimately aiming to reduce the number of medical visits and overall healthcare costs.

Arcadian Telepsychiatry

Seed Round in 2016
Arcadian Telepsychiatry, LLC is a provider of psychiatric services that connects mental health professionals with patients in both remote and urban locations. The company offers a comprehensive range of services, including on-demand emergency consultations for emergency departments and crisis centers, inpatient consultations, initial psychiatric evaluations, medication management, and scheduled clinics for children, adolescents, and adults. Additionally, Arcadian conducts pre-admission psychiatric assessments, staffing conferences with hospital personnel, and provides training and education on psychiatric emergency services and telepsychiatry. The organization also facilitates a network for video conferencing and Internet access among hospitals, clinics, and public health departments, and delivers behavioral health solutions for skilled nursing and assisted living facilities. Founded in 2012 and headquartered in Fort Washington, Pennsylvania, Arcadian Telepsychiatry aims to enhance access to mental health care while improving collaboration between providers, families, and patients.

Sweet Note Bakery

Seed Round in 2016
Sweet Note Bakery is a gluten-free and allergen free bagel manufacturer based in Manayunk. It recreated an authentic New York-style bagel to be completely free of the top 8 common food allergens, along with being gluten-free. Sweet Note Bakery ensures to use only high quality natural ingredients in their products to deliver nothing but the best.

Guiding Technologies

Seed Round in 2016
Guiding Technologies is a Philadelphia-based start-up dedicated to helping individuals with autism reach their full potential. Our product, GAINS™, is the first haptic feedback guidance and analysis software program designed exclusively for Applied Behavioral Analysis instruction management. GAINS™ guides and track ABA instruction in real-time with unprecedented detail and ease. It records each activity or trial with tactile input and unobtrusive audio response, avoiding any client distraction. The haptic feedback and seamless program-to-program transitions allow staff to focus on client instruction. Bulky program binders are consolidated into a tablet computer, and after-session reports can include detailed real-time performance data. GAINS™ automatically retrieves and evaluates client progress and staff management reporting with clearly designed charts and graphs – allowing you to maximize the performance of your organization.

Allevi

Seed Round in 2015
Allevi develops innovative tools for designing and engineering 3D tissues, focusing on bioprinting technology. The company offers desktop 3D bioprinters that allow users to create functional three-dimensional living tissues using various biomaterials and cell lines. Additionally, Allevi provides bioinks made from collagen and hyaluronic acid, which are available for purchase online. Their cloud-based platform, Bioprint Online, enables users to design complex structures, define materials, and monitor the printing process. Allevi's products serve a diverse clientele, including researchers in tissue engineering, regenerative medicine, and cell biology, as well as industrial and pharmaceutical companies for drug testing and development, and educators. Established in 2014 and based in Philadelphia, Pennsylvania, Allevi was formerly known as BioBots, Inc.

Defend Your Head

Seed Round in 2015
Defend Your Head of Chester Springs, PA has developed a patented soft shell protective helmet, the “ProCap”, to significantly increase the protective abilities of existing sports helmets and reduce head injury on the field. While helmet advances over the last 20 years focused on internal padding to prevent skull fracture, DYH’s unique technology and design works in tandem with existing helmets to provide superior protection, while outperforming its competition in both ease of use and application. In independent lab tests it was shown to absorb and dissipate energy, reduce the speed of impact, and deflect glancing blows to significantly reduce sports injuries. Unlike competitors’ products, DYH’s ProCap is available in custom colors, is decal-friendly and is both heat and cold resistant. The core technology was spawned at a firm funded by private investors, physicians, and Ben Franklin. That company merged into Defend Your Head in 2013 where the product was advanced and an additional patent was acquired. Market launch is scheduled for late summer. DYH is led by John Roman who spent 9 years in the NFL, was President of Merrill Lynch Trust Company, and founded Valley Forge Capital Advisors. He is joined by Frank Lytle who has a 40 year career in product design and manufacturing and grew several product lines from inception into millions in sales; and Greg Lewis, CFO, who has a sales, marketing and finance experience across several industries including financial services.

CrowdJoy

Venture Round in 2015
CrowdJoy is a mobile application based in Doylestown, Pennsylvania, that focuses on enhancing the event experience for fans. Founded in 2012, the app allows users to privately share their locations with friends while also helping them discover and enjoy parties on game days and various events. In addition to geotracking features, CrowdJoy offers location-aware event management software that enables event hosts to engage their audience and monetize their gatherings. This combination of features fosters community building around events and assists fans in finding the places that matter to them.

American Aerospace Technologies

Seed Round in 2015
American Aerospace Technologies, Inc. specializes in long-endurance unmanned aircraft systems (UAS) and flight services, primarily serving the oil and gas industry. The company offers comprehensive UAS integration solutions, including the development of advanced payloads, sensors, and communication systems designed to collect and deliver critical data across various applications such as pipeline integrity management, facilities inspection, and emergency response. American Aerospace provides its clients—ranging from Fortune 500 companies to government agencies—with high-quality operations and a diverse array of data products, including survey-grade mapping systems and methane detection technologies. Incorporated in 2000 and based in Conshohocken, Pennsylvania, the company adheres to FAA regulations while ensuring safe and efficient operation of its UAS.

Yorn

Seed Round in 2015
Yorn is a real-time feedback platform for healthcare, businesses, and hospitality services that enables its customers and participants to provide a real-time feedback. It helps organizations understand and improve the customer experience. Yorn was founded by Rick Rasansky in 2009 and is headquartered in Philadelphia, Pennsylvania.

Atrin Pharmaceuticals

Pre Seed Round in 2015
Atrin Pharmaceuticals LLC is a biopharmaceutical company based in Doylestown, Pennsylvania, focused on the discovery and development of innovative cancer treatments. Founded in 2011, the company is developing its lead drug candidates, ATRN-502, a p53 activator, and ATRN-507, a dual ligand that selectively targets cancer cells. Atrin is also advancing a proprietary platform called Atrize, which utilizes phenotypic FACS-based screening for rapid identification of effective drug candidates and evaluation of personalized medicine approaches. The company's research aims to address cancers linked to synthetic lethality and deregulated DNA damage response, with a focus on creating treatments that are effective against cancer cells while minimizing impact on healthy cells. Through its innovative methodologies, Atrin Pharmaceuticals seeks to change the landscape of cancer therapy.

Prescribe Well

Seed Round in 2015
PrescribeWell, Inc. is a Hatfield, Pennsylvania-based company that offers a platform-as-a-service designed to assist healthcare providers in tracking and analyzing behavioral modifications, such as obesity treatment, smoking cessation, and stress management. The platform allows healthcare providers to seamlessly integrate its software solution into existing electronic medical records systems, creating a physician-centric hub that supports wellness regimens for patients while optimizing billing processes for providers. By facilitating effective patient-physician engagement and ongoing communication, PrescribeWell aims to enhance patient outcomes in health management, disease prevention, and lifestyle modifications. The company was incorporated in 2012.

Kynectiv

Seed Round in 2015
Kynectiv, Inc. specializes in simulation-based products and technology platforms that cater to global audiences, particularly in the healthcare sector. The company offers a learning platform that enables organizations to design assessment, education, and training programs, enhancing decision-making through real-world engagement. Notable products include CommSim, which facilitates remote interactions between role-playing coaches and learners, and Synapse DX, a comprehensive solution aimed at helping healthcare organizations understand and influence audience decision-making experiences. Founded in 2010 and headquartered in Chadds Ford, Pennsylvania, Kynectiv was previously known as DecisionSim, Inc. and has operated as a subsidiary of US HealthConnect since 2019.

EnviroKure Incorporated

Seed Round in 2014
EnviroKure Incorporated, established in 2011 and located in Philadelphia, Pennsylvania, specializes in the manufacturing and distribution of pathogen-free liquid organic fertilizers suitable for various applications, including agriculture, hydroponics, professional turf, and home gardening. The company employs patented technology to convert nutrients and microbes from chicken manure, an environmentally challenging waste, into high-value microbial fertilizers that comply with USDA National Organic Program and FDA Food Safety standards. EnviroKure's innovative products deliver a strong return on investment for both conventional and organic growers. Its diverse customer base spans 37 states in the U.S., including significant clients in the Midwest who manage over 130,000 acres and influence decisions on nearly 1 million acres, indicating a substantial potential market for its fertilizers.

Livegenic

Seed Round in 2014
Livegenic provides enterprise technology services and a virtual collaboration platform for insurance. The company connects every part of the claims ecosystem to help insurance organizations reduce costs, improve customer satisfaction, and mitigate business-related risk. Its cloud-based platform includes an app and browser-based solutions for real-time video collaboration, field documentation, and customer self-service that enables live video collaboration between an in-house adjuster, appraiser, and the policyholder, all without disconnecting the call. Livegenic also provides a suite of mobile solutions for insurance professionals that enable adjusters and inspectors to capture live and offline pictures and videos. Founded in 2014, LiveGenic is headquartered in Philadelphia, Pennsylvania.

Sweet Note Bakery

Seed Round in 2014
Sweet Note Bakery is a gluten-free and allergen free bagel manufacturer based in Manayunk. It recreated an authentic New York-style bagel to be completely free of the top 8 common food allergens, along with being gluten-free. Sweet Note Bakery ensures to use only high quality natural ingredients in their products to deliver nothing but the best.

InstaMed

Venture Round in 2014
InstaMed Communications, LLC, founded in 2004 and headquartered in Philadelphia, Pennsylvania, operates a healthcare payments network that connects providers, payers, and consumers through a unified cloud-based platform. The company offers several products, including InstaMed Online for Providers and InstaMed Online for Payers, both of which facilitate secure management of healthcare payment transactions with role-based security. Additionally, InstaMed Connect integrates healthcare payments into existing IT applications via APIs. By streamlining electronic transactions and consolidating payment processes, InstaMed aims to reduce the risks and complexities associated with multiple payment vendors, ultimately enhancing consumer satisfaction and enabling providers to collect payments more efficiently. As of 2019, InstaMed operates as a subsidiary of JPMorgan Chase Bank, National Association.

Allevi

Seed Round in 2014
Allevi develops innovative tools for designing and engineering 3D tissues, focusing on bioprinting technology. The company offers desktop 3D bioprinters that allow users to create functional three-dimensional living tissues using various biomaterials and cell lines. Additionally, Allevi provides bioinks made from collagen and hyaluronic acid, which are available for purchase online. Their cloud-based platform, Bioprint Online, enables users to design complex structures, define materials, and monitor the printing process. Allevi's products serve a diverse clientele, including researchers in tissue engineering, regenerative medicine, and cell biology, as well as industrial and pharmaceutical companies for drug testing and development, and educators. Established in 2014 and based in Philadelphia, Pennsylvania, Allevi was formerly known as BioBots, Inc.

AlphaPoint

Seed Round in 2014
AlphaPoint Corporation is a software developer specializing in technologies for digital currency exchanges. Founded in 2013 and headquartered in New York, the company offers a comprehensive platform that includes solutions for launching and operating crypto markets, as well as tools for asset digitization and automated market-making. Its products, which serve over 150 clients in 35 countries, include a white-label digital asset trading platform, liquidity services, custody solutions, and yield offerings. AlphaPoint's technology enables various financial entities, such as exchange operators, brokerages, and market makers, to efficiently digitize assets and streamline their operations. With additional offices in Philadelphia and San Francisco, AlphaPoint has established itself as a key player in facilitating blockchain strategies for both startups and established institutions.

Superior Solar Design

Seed Round in 2014
Superior Solar Design LLC is located in King of Prussia, Pennsylvania, a suburb just west of Philadelphia. Their roots began as a "PA Sunshine Grant" approved solar electric and solar heating system sales and installation company for commercial and residential customers. Superior Solar Design LLC is immersed in all things solar powered and recognized the opportunity to build a superior solar charging table and solar powered mobile device charging stations. Their off grid solar power centers and solar charging tables make an excellent addition anywhere or anyplace under the sun. Just like all of their solar projects the SolarPower Table solar charging table is designed and built to be the best in class and perform beyond expectations.

Fischer Block

Seed Round in 2014
Fischer Block, Inc. is a technology company focused on enhancing the electrical power industry through advanced high-speed sensor solutions embedded within the electrical grid. Established in 2013 and based in Royersford, Pennsylvania, the company offers the ASAP Grid Sensor Analytics System, which simplifies the installation and maintenance of extensive sensor networks. This system provides critical functionalities such as fault detection, substation monitoring, and power quality analysis while also addressing cybersecurity threats. Fischer Block's innovative approach allows for rapid installation without the need for new wiring, significantly reducing costs and installation times compared to traditional methods. The company's technology is applicable not only in the energy sector but also in transportation, manufacturing, mining, and chemical processing industries, positioning it as a leader in the Industrial Internet of Things.

Polynetworks

Seed Round in 2014
Polynetworks LLC, based in Narberth, Pennsylvania, offers wireless networking services tailored for government entities, contractors, and commercial sectors. Established in 2009, the company specializes in telecommunications and provides a variety of services, including research, consulting, integration, and product design. With over five years of experience in broadband wireless networks, both static and mobile, Polynetworks employs extensive hardware and software expertise to develop effective, real-world systems. Their holistic approach ensures the delivery of practical solutions, and they also engage in training, installation, and troubleshooting of tactical and mission-critical wireless systems. By addressing complex organizational challenges, Polynetworks enhances operational performance for its clients in the wireless communications field.

Powerlytics

Venture Round in 2014
Powerlytics helps organizations address significant risk and compliance-related challenges. Powerlytics does this by providing unique economic and financial reports, and analytical insights, that mainly leverage U.S. government-supplied data. These products utilize intelligence about individuals, customers, suppliers and competitors to enable organizations to make more informed decisions. Powerlytics’ initial product allows companies to generate benchmarking and market sizing reports covering 27 million businesses and 140 million individuals broken down to very granular geographic, industry and size (sales, assets, employees) parameters. Powerlytics was founded in 2011 and is headquartered in Doylestown, Pennsylvania, USA.

Yorn

Seed Round in 2014
Yorn is a real-time feedback platform for healthcare, businesses, and hospitality services that enables its customers and participants to provide a real-time feedback. It helps organizations understand and improve the customer experience. Yorn was founded by Rick Rasansky in 2009 and is headquartered in Philadelphia, Pennsylvania.

Stabiliz Orthopaedics

Seed Round in 2014
Stabiliz Orthopaedics, LLC, founded in 2009 and based in Exton, Pennsylvania, specializes in the development and distribution of orthopedic devices. The company focuses on creating innovative enhancements to existing orthopedic medical technologies, utilizing FDA-approved methods. Their primary aim is to improve clinical outcomes and simultaneously reduce costs for healthcare systems, addressing the challenges faced by both patients and providers in the orthopedic field.

Infarct Reduction Technologies

Seed Round in 2014
Infarct Reduction Technologies develops a therapeutic device for ischemic pre-conditioning protocol. The company offers LifeCuff, a non-invasive manually-inflated blood pressure cuff for remote ischemic conditioning in heart attack, stroke, sepsis, liver surgery, traumatic brain injury, and other critical condition patients. The company is headquartered in Waldwick, New Jersey.

Advent Therapeutics

Seed Round in 2014
Advent Therapeutics is a pharmaceutical company based in Lumberville, Pennsylvania, dedicated to developing therapies for micro-orphan applications, specifically targeting serious unmet medical needs in neonatal and pediatric populations. The company focuses on legacy drugs aimed at treating disorders in newborn infants, particularly those in intensive care units. By creating prenatal, neonatal, and pediatric medications, Advent Therapeutics enables healthcare professionals to provide advanced care for vulnerable patients, addressing critical gaps in existing treatment options for this underserved demographic.

Photosonix Medical

Seed Round in 2014
Photosonix Medical is a company based in Ambler, Pennsylvania, focused on developing innovative skincare treatments for chronic bacterial infections, particularly in the context of moderate to severe acne. The company has created CLENS™, a device that synergistically combines low-level ultrasound stimulation with blue light energy to effectively target biofilms, which are often responsible for persistent skin issues. By offering a home-use treatment option, Photosonix Medical aims to empower users to manage their acne while preventing permanent skin scarring. The primary audience for its products includes dermatologists and primary care physicians who are involved in prescribing effective acne treatments.

Setvi

Seed Round in 2014
Setvi, Inc. operates a mobile sales enablement platform designed to enhance the efficiency of the sales process for manufacturing and wholesale distribution companies. The Setvi platform allows marketing and sales leaders to distribute, manage, and update sales materials from a single cloud-based system, enabling sales representatives to create dynamic presentations by integrating various content types such as PowerPoint, PDF documents, videos, and live websites. This platform supports personalized sales campaigns and provides analytics on content usage and sales performance. Additionally, it streamlines workflows through integrations with ERP, CRM, and PIM systems, facilitating quicker quote generation and revealing upselling opportunities. By leveraging data-driven insights, Setvi enhances sales effectiveness, boosts productivity, and empowers marketing teams to optimize conversions. Established in 2013, Setvi is headquartered in Newtown Square, Pennsylvania.

Vy Corporation

Seed Round in 2014
Vy Corporation is a software development company based in Wayne, Pennsylvania, that specializes in shape detection and object analysis software for the medical imaging market. The company offers CytoSavvy.com, a cloud-based image analysis and data collection service that enables users to upload and analyze images, particularly useful for identifying clusters of cells in liver and kidney biopsies using its patented CellQuant™ search technology. In addition, Vy Corporation provides VectorSavvy.com, which grants users access to advanced image analysis tools for loading images and viewing results, and it also develops custom projects tailored to specific client needs. The company's mission is to assist pathologists and medical researchers in efficiently identifying and analyzing complex cell structures, enhancing the reliability of data for research and diagnostics.

Cro Analytics

Seed Round in 2014
CRO Analytics, LLC specializes in providing data assessment tools and services tailored for sponsors and contract research organizations. The company has developed Performer, a cloud-based clinical trial performance system that includes a trial assessment platform offering in-trial alerts. This platform enables clinical research executives and management teams to enhance research quality, efficiency, and overall performance while achieving cost savings. By utilizing a proprietary validated process, CRO Analytics collects, analyzes, and reports on quality performance indicators in outsourced clinical research. The platform is designed to deliver insights into clinical research performance by capturing thousands of assessments from biopharma and service provider personnel directly involved in outsourced clinical research. Incorporated in 2011 and based in New Hope, Pennsylvania, CRO Analytics stands out with its ability to provide objective, validated performance data across various metrics, including service provider, sponsor, region, study type, phase, functional area, and therapeutic area.

HealthQx

Series A in 2014
HealthQX specializes in Value-based Payment (VBP) analytic software solutions for health plans and providers. Its VBP analytics platform, ClarityQx, provides the capabilities to design, implement, and monitor the on-going performance of payment models such as episodic, bundled, or accountable care arrangements. The company was founded in 2012 and is based in King Of Prussia, Pennsylvania.

SilverLine Global

Seed Round in 2014
SilverLine Global, Inc. operates a digital video publishing platform tailored for the endurance sports industry, connecting event directors and brands in sports such as running, triathlon, cycling, and adventure events. The platform allows users to create custom video experiences by uploading race footage and engaging content, while sponsors can post targeted advertisements. Additionally, SilverLine NOW serves as a publishing network, enabling event organizers, product manufacturers, and content creators to utilize advancements in digital media technology. By offering services such as video hosting, asset management, and analytics, SilverLine enhances revenue opportunities for event managers through targeted digital activations. Founded in 2012, the company is headquartered in Philadelphia, Pennsylvania, with a subsidiary located in Bengaluru, India.

Fitly

Seed Round in 2014
Fitly, Inc. develops a mobile web application and countertop device aimed at helping families and children plan, purchase, and prepare healthy meals. The SmartPlate App features food recognition technology, allowing users to choose from specific health goals or create custom plans. When paired with a countertop device, it offers precise image recognition, nutrient analysis, and meal tracking capabilities. The app also provides access to a comprehensive database of packaged and restaurant foods for convenient tracking, along with personalized tips and feedback. Additionally, the SmartPlate TopView device analyzes entire meals and offers guidance on healthy eating habits. Fitly's solutions address various health-related needs, including weight management, endurance, hydration, and portion control. Established in 2011 and headquartered in Philadelphia, Pennsylvania, Fitly is committed to enhancing human health and longevity through innovative nutritional technology.

VUID, Inc.

Angel Round in 2013
VUID, Inc., incorporated in 2013 and based in Philadelphia, Pennsylvania, specializes in mobile identity solutions through its two-factor authentication system for mobile devices. The company has developed a mobile-centric identification system that allows users to log in to various applications using a unique VUID number. One of its notable products is Spotlight, a media and social media application that launched on Android and iPhone platforms in late 2013 and early 2014. VUID has established partnerships with organizations such as the Knight Foundation and Interstate General Media to enhance its offerings and expand its reach in the mobile technology sector.

Cloudnexa

Series A in 2013
Cloudnexa, Inc. specializes in cloud management solutions and serves as an authorized reseller and consulting partner for Amazon Web Services (AWS). The company offers its vNOC platform, which streamlines cloud migration and provides users with a comprehensive dashboard for managing their cloud environments. This platform includes features such as real-time reporting, cost analysis, and management of billing, resource allocation, governance, and compliance. Cloudnexa also assists in migrating various applications, including SharePoint, ERP, and CRM systems to the cloud. Catering to a diverse clientele that includes commercial enterprises, higher education institutions, non-profits, and government sectors, Cloudnexa was founded in 2008 and is headquartered in Philadelphia, Pennsylvania, with an additional office in Cairo, Egypt.

Clutch

Venture Round in 2013
Clutch serves as a customer marketing platform for business-to-consumer brands. It provides traditional marketing CRM, loyalty, gift card, mobile, email, and direct mail solutions. The company was created to help businesses succeed in an evolving marketing landscape. Since 2012, they have continued to grow their platform into an innovative, data-centric marketing solution with one focus that empowering brands with the best technology so that they can identify, understand and motivate their customers.

S4 Worldwide

Seed Round in 2012
S4 Worldwide LLC (S4W), headquartered in Doylestown, Pennsylvania, provides mobile real-time situational awareness technologies to business decision-makers. Using environmentally friendly, solar and wind powered trailer-mounted systems, video, audio, and sensor data is gathered from remote sites and electronically presented to users through a secure website and onto their laptops, tablets, or smartphones. S4W’s vision is to be the leader in responsive, real-time dynamic business tools for decision-makers.

Relmada Therapeutics

Series A in 2012
Relmada Therapeutics, Inc. is a clinical-stage biotechnology company based in New York, focused on developing innovative treatments for central nervous system (CNS) diseases. The company is advancing its lead product candidate, d-Methadone (also known as esmethadone or REL-1017), a novel NMDA receptor antagonist currently in late-stage development as an adjunctive treatment for major depressive disorder in adults. Additionally, Relmada is working on several other drug formulations, including LevoCap ER, an abuse-resistant sustained-release version of levorphanol; BuTab, an oral formulation of buprenorphine; and MepiGel, a topical formulation of the local anesthetic mepivacaine, which has received orphan drug designation. Founded in 2004, Relmada Therapeutics aims to address significant unmet medical needs in the treatment of CNS disorders.

Plehn Analytics

Seed Round in 2012
Plehn Analytics Corp., a Philadelphia, PA-based provider of economic and financial reports. It was renamed Powerlytics in 2013.

Holganix

Seed Round in 2012
Holganix, Inc. is a manufacturer of plant-based bio-stimulant soil supplements aimed at enhancing soil health and promoting sustainable plant growth. Founded in 2010 and headquartered in Glen Mills, Pennsylvania, the company offers a range of products including tree and shrub solutions, golf course treatments, agriculture products, and flower programs. A key offering is Holganix Bio 800+, which contains beneficial microorganisms, microbe food, and nutrient enhancers that optimize soil conditions. Holganix's products are designed to reduce fertilizer use by up to 90%, thereby lowering costs for landscape and lawn care companies while minimizing environmental impact. The company sells its products through distributors in the United States and also offers online sales.

Tadpoles

Seed Round in 2012
Tadpoles LLC is a company based in Philadelphia, Pennsylvania, specializing in mobile applications designed for childcare providers and parents. Its flagship offerings include TADPOLES MOBILE, which enables teachers and directors to generate daily reports, manage attendance, and share photos, as well as TADPOLES WEBMANAGER, which allows directors to oversee multiple centers and classrooms, manage employee and student profiles, and access attendance reports. Additionally, TADPOLES WEB provides parents with updates, daily reports, and access to photo albums. The applications facilitate secure and private communication, allowing teachers to capture and share photos, videos, and notes about children's activities in real-time. As of February 2015, Tadpoles operates as a subsidiary of Teaching Strategies, LLC.

EyeIC

Venture Round in 2012
EyeIC, Inc. is a medical technology company focused on developing and commercializing imaging technologies for eye care applications. Based in Wayne, Pennsylvania, EyeIC serves eye care professionals and clinics by offering the MatchedFlicker device, which monitors the onset and progression of glaucoma through change detection in time series retinal photographs. The technology aligns and registers images taken at different times, creating a superimposed view that aids in accurate diagnosis. Additionally, EyeIC's software includes an easy-to-use application that streamlines image processing, interpretation, and reporting, facilitating the detection of various retinal conditions such as diabetic retinopathy and retinopathy of prematurity. Established in 2004, EyeIC aims to simplify workflows for clinicians and enhance patient care in the field of ophthalmology.

OneTwoSee

Venture Round in 2011
OneTwoSee is a Philadelphia-based company that sits at the intersection of digital media, sports and technology. We're on our third-generation of a highly scalable technology platform that delivers real-time sports gamecenters by combining statistics, game data, advanced analytics and social media into a rich, engaging fan experience. Our gamecenters are white labeled and easily integrate into customers' own branded sites and platforms -- be it on browser-based PCs, tablets, smartphones, smart TVs and in-arena displays. Our licensed products -- applications spanning major collegiate and professional sports including baseball, football, basketball, hockey and soccer -- enable anyone with an audience interested in big-time sports to further monetize their audiences with new, high-value ad and sponsorship inventory. Customers easily plug into our managed platform and see immediate ROI. OneTwoSee's customers now include some of the largest names in sports media along with leading companies in the publishing, consumer electronics and enterprise technology sectors.

Ticketleap

Venture Round in 2011
TicketLeap, Inc. is an online event ticket selling and registration service founded in 2003 and based in Philadelphia, Pennsylvania. The company offers a self-service ticketing platform that enables event organizers to sell tickets for a variety of events, including art fairs, concerts, festivals, and theater productions. TicketLeap provides users with branded event pages, built-in management tools, promotional features, and flexible ticketing options, allowing for quick and efficient event setup. The platform is designed to enhance community engagement and streamline the ticketing process, making it a preferred choice for event creators both in the United States and internationally.

Real Time Tomography

Seed Round in 2011
Real Time Tomography, LLC specializes in developing advanced imaging software solutions for medical imaging systems, particularly in the field of breast cancer detection. Founded in 2006 and based in Villanova, Pennsylvania, the company offers two primary products: Adara, which enhances digital mammography images to improve tissue contrast and lesion visibility, and Briona, a software that reconstructs 3D images from 2D tomosynthesis data. In addition to its software offerings, Real Time Tomography provides technical support and consultation services aimed at optimizing detector and system design for enhanced image quality and processing speed. The company primarily serves manufacturers of mammography systems and PACS workstations, contributing to improved diagnostic accuracy and clinical workflows in healthcare settings.

Holganix

Seed Round in 2011
Holganix, Inc. is a manufacturer of plant-based bio-stimulant soil supplements aimed at enhancing soil health and promoting sustainable plant growth. Founded in 2010 and headquartered in Glen Mills, Pennsylvania, the company offers a range of products including tree and shrub solutions, golf course treatments, agriculture products, and flower programs. A key offering is Holganix Bio 800+, which contains beneficial microorganisms, microbe food, and nutrient enhancers that optimize soil conditions. Holganix's products are designed to reduce fertilizer use by up to 90%, thereby lowering costs for landscape and lawn care companies while minimizing environmental impact. The company sells its products through distributors in the United States and also offers online sales.

Zagster

Pre Seed Round in 2010
Zagster Inc. specializes in designing, building, and operating bike-sharing programs for various entities, including universities, corporate campuses, hotels, and residential communities across North America. Founded in 2007 and headquartered in Cambridge, Massachusetts, the company provides a comprehensive bike-sharing solution that encompasses system design, installation, sharing technology, maintenance, and rider support services. Zagster's mobile application allows users to unlock, ride, and return bikes conveniently, enhancing accessibility to biking as a form of transportation. The company also offers services for shared scooters and electric bikes, catering to communities of all sizes and aiming to promote biking as a preferred mode of transport.

Spectrum Devices

Venture Round in 2010
Spectrum Devices Corporation specializes in the design and manufacture of high-power transistors for radio frequency (RF) and microwave applications. Founded in 2003 and headquartered in Hatfield, Pennsylvania, the company produces a range of products, including bipolar vertical-drain lateral-diffused MOS (VDMOS) transistors and RF transistors for communication and power generation. Spectrum Devices also provides direct, drop-in replacements for most high-power requirements, allowing clients to select suitable devices for their needs. Additionally, the company offers custom services to support ongoing production of existing designs. With operations in New York and Asia, Spectrum Devices is positioned to serve a global market.

Ticketleap

Series A in 2008
TicketLeap, Inc. is an online event ticket selling and registration service founded in 2003 and based in Philadelphia, Pennsylvania. The company offers a self-service ticketing platform that enables event organizers to sell tickets for a variety of events, including art fairs, concerts, festivals, and theater productions. TicketLeap provides users with branded event pages, built-in management tools, promotional features, and flexible ticketing options, allowing for quick and efficient event setup. The platform is designed to enhance community engagement and streamline the ticketing process, making it a preferred choice for event creators both in the United States and internationally.

Novasentis

Series A in 2008
Novasentis, Inc. specializes in the design and development of electro-mechanical polymer actuator and sensor technology. The company has pioneered the world's first electro-mechanical polymer, which is recognized as the thinnest and most flexible haptic actuator available. This technology is utilized in various applications, including ultra-thin keyboards, smartphones, wearable devices, and gaming devices, enhancing user interaction through localized haptic vibrations and sound effects. By combining consumer electronics with sensory interaction, Novasentis provides innovative solutions that facilitate deeper physical and emotional connections between users and their devices. Founded in 2006 and headquartered in Berkeley, California, Novasentis also maintains offices in Pennsylvania, Japan, and Korea. As of June 2019, it operates as a subsidiary of KEMET Electronics Corporation.

SkillSurvey

Seed Round in 2007
SkillSurvey Inc. offers cloud-based reference checking and credentialing solutions designed to enhance the hiring process for employers. Founded in 2001 and based in Berwyn, Pennsylvania, the company provides various products, including SkillSurvey Reference, which automates the reference checking process, and Hire 360, an online assessment tool that predicts a candidate's job performance. Additionally, SkillSurvey Credential OnDemand facilitates immediate online responses from applicants and references, while SkillSurvey Source aids in candidate sourcing through referrals. The company's technology is particularly beneficial for sectors such as healthcare, higher education, staffing, and retail, enabling organizations to efficiently verify candidate qualifications and skills. By leveraging data-driven insights, SkillSurvey's patented solutions help clients make informed hiring decisions, ultimately improving business performance and employee retention.

Acuity Pharmaceuticals

Series B in 2004
Acuity Pharmaceuticals is a pharmaceutical company that is focused on the treatment and prevention of ophthalmic diseases. It develops treatments for age-related macular degeneration and diabetic retinopathy. The company offers Cand5, a clinical compound that is able to shut down vascular endothelial growth factor. Acuity Pharmaceuticals was acquired by OPKO Health in June 2011. Acuity Pharmaceuticals was founded in 2007 and is based in Philadelphia, Pennsylvania.

SFA Therapeutics

SFA Therapeutics, Inc. is a development-stage bio-pharmaceutical company located in Jenkintown, Pennsylvania. The company specializes in creating drugs derived from microbiome-derived metabolites aimed at treating chronic inflammatory diseases and cancer. By harnessing compounds discovered in the human microbiome, SFA Therapeutics seeks to provide innovative therapeutic solutions for various medical conditions, including autoimmune diseases and liver disorders.
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