Arboretum Ventures

Shoulder Innovations, Inc. is a medical device company based in Holland, Michigan, specializing in orthopedic solutions for shoulder replacement surgery. Founded in 2009, the company has developed an advanced Total Shoulder Replacement System that features innovative inset glenoid fixation technology, addressing the critical issue of glenoid implant stability during shoulder arthroplasty. This technology not only enhances the robustness of the glenoid platform but also simplifies the surgical instrumentation, aiming to reduce operative time and costs. The company's products are marketed through distribution partners in the United States and are designed to improve patient outcomes by minimizing the risk of glenoid loosening, which is a leading cause of revision surgeries. By focusing on reliable fixation and simplified surgical techniques, Shoulder Innovations strives to enhance the efficacy and longevity of shoulder implants while potentially lowering overall healthcare costs.

Francis Medical, Inc., established in 2018 and based in Maple Grove, Minnesota, specializes in the development of innovative medical devices utilizing water vapor technology to treat various urological cancers. The company focuses on prostate, kidney, and bladder cancers, aiming to provide minimally invasive treatments that can potentially reduce life-altering side effects common with traditional methods. Their approach involves using the thermal energy stored in sterile water vapor to ablate cancerous tissue via a simple transurethral procedure.

AtaCor Medical, Inc. is a medical device company based in San Clemente, California, specializing in innovative solutions for cardiac pacing and rhythm management. Founded in 2014, the company has developed the AtaCor EV Temporary Pacing System, which allows for temporary pacing through a parasternal approach. This system advances a custom pacing lead into the extracardiac tissue between the ribs and pericardium, effectively restoring cardiac rhythm without the need for traditional pacing leads or hardware that typically attach directly to the heart. By facilitating quick deployment of temporary or emergency pacing therapy, AtaCor Medical addresses critical needs in cardiac care.

ViaLase is a medical technology company that specializes in developing an image-guided femtosecond laser surgical system for the treatment of open-angle glaucoma. Founded in 2019 and based in Corona Del Mar, California, the company focuses on utilizing micron-resolution optical coherence tomography (OCT) technology. This innovative approach enables the creation of customized, micron-sized drainage channels through the trabecular meshwork, connecting the anterior chamber to Schlemm's canal without the need for surgical penetration or opening of the eye. By offering an efficient and non-invasive treatment option, ViaLase aims to enhance the management of glaucoma for medical professionals and their patients.

Flosonics Medical is a Canadian medical device company founded in 2017, specializing in the development of non-invasive sensors aimed at enhancing the management of critically ill patients. Its flagship product, the FloPatch, is a wearable ultrasound sensor designed to monitor blood flow in patients post-clinical intervention, thereby addressing critical clinical needs. The FloPatch is particularly beneficial for healthcare professionals, including physicians, nurses, and paramedics, operating in various high-pressure environments such as ambulances, emergency departments, operating rooms, and intensive care units. The device is notable for its portability, wireless connectivity with tablets and other medical equipment, and user-friendly functionality, all of which contribute to improved patient care in urgent medical situations. Flosonics Medical, previously known as Ke2 Technologies, rebranded in September 2017.

Reprieve Cardiovascular, Inc. is a medical device company based in Milford, Massachusetts, established in 2018. The company specializes in developing innovative fluid management technologies aimed at treating congestive heart failure. Its flagship product, the Reprieve technology, offers a solution for clinicians to precisely control the fluid volume in patients suffering from acute decompensated heart failure (ADHF). This ability to manage fluid levels is essential for improving cardiac care and assisting in the decongestion process for these patients. Reprieve Cardiovascular operates as a subsidiary of CardioRenal Systems, Inc.

Avation Medical, Inc. is a company focused on developing a non-invasive closed-loop neuromodulation system aimed at treating overactive bladder in a home setting. Incorporated in 2016 and based in Columbus, Ohio, Avation Medical is at the forefront of innovation in wearable nerve stimulation systems. The company emphasizes empowering patients to manage their therapies, facilitating a more personalized approach to care. By leveraging advanced technologies, Avation Medical seeks to transform the neuromodulation market, enhancing the quality of care for individuals with chronic conditions through patient-centric solutions.

Virtual Incision is a medical technology company focused on developing innovative robotic-assisted surgical devices, specifically targeting colon resection. The company has created the MIRA (Miniaturized In vivo Robotic Assistant) Platform, which is a pioneering miniaturized surgical robotic support device. This platform allows for efficient operating room setups in minutes, eliminating the need for cumbersome equipment handling such as draping or docking. By enhancing the surgical process, Virtual Incision aims to improve clinical outcomes while also addressing healthcare costs, positioning itself as a leader in the field of robotic-assisted surgery.

Cardiac Dimensions, Inc. is a medical device company focused on developing innovative minimally invasive treatments for heart failure and associated cardiovascular issues. Founded in 2000 and headquartered in Kirkland, Washington, with additional operations in Sydney, Australia, and Offenbach, Germany, the company is known for its Carillon Mitral Contour System. This permanent implant is designed specifically for the treatment of functional mitral regurgitation, utilizing a catheter-based approach to reshape the mitral valve and effectively reduce regurgitation. By providing a non-surgical option for patients, Cardiac Dimensions aims to improve outcomes for those suffering from heart-related conditions.

Boomerang Medical is a female-led bioelectronic medical technology company based in Mountain View, California, on the campus of El Camino Hospital. The firm is dedicated to revolutionizing the management of autoimmune diseases through the development of innovative bioelectric neuromodulation technologies. Boomerang Medical's commitment to advancing treatment options is underscored by its receipt of Breakthrough Device Designation from the FDA for its technology aimed at treating Crohn's disease and ulcerative colitis. By focusing on improving the quality of life for patients, Boomerang Medical seeks to disrupt traditional treatment paradigms in the field of autoimmune illnesses.

Koya Medical, Inc. is a healthcare company based in Oakland, California, founded in 2018. The company specializes in developing innovative wearable therapeutic devices aimed at treating cancer-related chronic lymphedema and various venous diseases. Koya Medical's technology offers active compression therapy that enhances mobility and personalized care, addressing limitations commonly associated with traditional compression methods. Its sensor-based closed-loop system provides patient-specific patterned compression, enabling healthcare providers to effectively manage conditions like chronic edema and chronic venous insufficiency. Through its breakthrough treatments, Koya Medical seeks to transform the standard of care for individuals affected by these debilitating conditions.

ViaLase is a medical technology company that specializes in developing an image-guided femtosecond laser surgical system for the treatment of open-angle glaucoma. Founded in 2019 and based in Corona Del Mar, California, the company focuses on utilizing micron-resolution optical coherence tomography (OCT) technology. This innovative approach enables the creation of customized, micron-sized drainage channels through the trabecular meshwork, connecting the anterior chamber to Schlemm's canal without the need for surgical penetration or opening of the eye. By offering an efficient and non-invasive treatment option, ViaLase aims to enhance the management of glaucoma for medical professionals and their patients.

Boomerang Medical is a female-led bioelectronic medical technology company based in Mountain View, California, on the campus of El Camino Hospital. The firm is dedicated to revolutionizing the management of autoimmune diseases through the development of innovative bioelectric neuromodulation technologies. Boomerang Medical's commitment to advancing treatment options is underscored by its receipt of Breakthrough Device Designation from the FDA for its technology aimed at treating Crohn's disease and ulcerative colitis. By focusing on improving the quality of life for patients, Boomerang Medical seeks to disrupt traditional treatment paradigms in the field of autoimmune illnesses.

Francis Medical, Inc., established in 2018 and based in Maple Grove, Minnesota, specializes in the development of innovative medical devices utilizing water vapor technology to treat various urological cancers. The company focuses on prostate, kidney, and bladder cancers, aiming to provide minimally invasive treatments that can potentially reduce life-altering side effects common with traditional methods. Their approach involves using the thermal energy stored in sterile water vapor to ablate cancerous tissue via a simple transurethral procedure.

Strata Oncology, Inc. is a precision oncology company focused on enhancing cancer care by facilitating access to precision medicine clinical trials and expediting drug approval processes. Based in Ann Arbor, Michigan, the company develops a comprehensive precision oncology platform that supports routine testing and efficient use of molecular data. Strata's offerings include The Strata Trial, a genomic testing program for systematic precision oncology implementation, and StrataNGS, a targeted assay for sequencing DNA and RNA from biopsies. Additionally, StrataPOINT integrates electronic medical record histories with molecular profiling to ensure eligible patients are tested and considered for trial enrollment. The company features a portfolio of pharma-sponsored therapeutic protocols, known as Strata Partnered Trials, aligned to specific biomarkers. Strata also operates The Strata Lab, a cancer sequencing facility, and maintains the Strata Precision Oncology Network, a collaborative entity aimed at promoting precision medicine initiatives. Formerly known as Strata Oncology Research, Inc., the company rebranded in 2016 and has been incorporated since 2015.

Flosonics Medical is a Canadian medical device company founded in 2017, specializing in the development of non-invasive sensors aimed at enhancing the management of critically ill patients. Its flagship product, the FloPatch, is a wearable ultrasound sensor designed to monitor blood flow in patients post-clinical intervention, thereby addressing critical clinical needs. The FloPatch is particularly beneficial for healthcare professionals, including physicians, nurses, and paramedics, operating in various high-pressure environments such as ambulances, emergency departments, operating rooms, and intensive care units. The device is notable for its portability, wireless connectivity with tablets and other medical equipment, and user-friendly functionality, all of which contribute to improved patient care in urgent medical situations. Flosonics Medical, previously known as Ke2 Technologies, rebranded in September 2017.

Koya Medical, Inc. is a healthcare company based in Oakland, California, founded in 2018. The company specializes in developing innovative wearable therapeutic devices aimed at treating cancer-related chronic lymphedema and various venous diseases. Koya Medical's technology offers active compression therapy that enhances mobility and personalized care, addressing limitations commonly associated with traditional compression methods. Its sensor-based closed-loop system provides patient-specific patterned compression, enabling healthcare providers to effectively manage conditions like chronic edema and chronic venous insufficiency. Through its breakthrough treatments, Koya Medical seeks to transform the standard of care for individuals affected by these debilitating conditions.

Cardiac Dimensions, Inc. is a medical device company focused on developing innovative minimally invasive treatments for heart failure and associated cardiovascular issues. Founded in 2000 and headquartered in Kirkland, Washington, with additional operations in Sydney, Australia, and Offenbach, Germany, the company is known for its Carillon Mitral Contour System. This permanent implant is designed specifically for the treatment of functional mitral regurgitation, utilizing a catheter-based approach to reshape the mitral valve and effectively reduce regurgitation. By providing a non-surgical option for patients, Cardiac Dimensions aims to improve outcomes for those suffering from heart-related conditions.

Fifth Eye Inc. is a medical software company based in Ann Arbor, Michigan, specializing in real-time analytics for patient health monitoring. The company develops an innovative clinical decision support system that continuously analyzes a patient's hemodynamic status to predict the risk of instability. Its advanced software utilizes artificial intelligence to process real-time ECG data, enabling minute-to-minute assessments and providing healthcare professionals with early warnings of potential complications hours in advance of traditional methods. By offering continuous patient trajectory forecasts and historical trend analyses without requiring electronic health record inputs, Fifth Eye aims to enhance proactive patient care, improve clinical outcomes, and reduce hospital costs. Formerly known as Trove Analytics, Inc., Fifth Eye was incorporated in 2017 and rebranded in June 2018.

SonarMD, LLC, based in Elgin, Illinois, develops a subspecialty practice platform focused on care coordination for patients with chronic conditions, particularly those related to gut health. The company offers services designed to improve the management of complex chronic diseases that often require high-cost medications. By enhancing patient engagement and optimizing specialty pharmacy resources, SonarMD aims to keep patients healthier and reduce hospitalizations. Their approach integrates care management solutions that streamline the healthcare experience for both patients and clinical teams, ultimately fostering better health outcomes.

Francis Medical, Inc., established in 2018 and based in Maple Grove, Minnesota, specializes in the development of innovative medical devices utilizing water vapor technology to treat various urological cancers. The company focuses on prostate, kidney, and bladder cancers, aiming to provide minimally invasive treatments that can potentially reduce life-altering side effects common with traditional methods. Their approach involves using the thermal energy stored in sterile water vapor to ablate cancerous tissue via a simple transurethral procedure.

Strata Oncology, Inc. is a precision oncology company focused on enhancing cancer care by facilitating access to precision medicine clinical trials and expediting drug approval processes. Based in Ann Arbor, Michigan, the company develops a comprehensive precision oncology platform that supports routine testing and efficient use of molecular data. Strata's offerings include The Strata Trial, a genomic testing program for systematic precision oncology implementation, and StrataNGS, a targeted assay for sequencing DNA and RNA from biopsies. Additionally, StrataPOINT integrates electronic medical record histories with molecular profiling to ensure eligible patients are tested and considered for trial enrollment. The company features a portfolio of pharma-sponsored therapeutic protocols, known as Strata Partnered Trials, aligned to specific biomarkers. Strata also operates The Strata Lab, a cancer sequencing facility, and maintains the Strata Precision Oncology Network, a collaborative entity aimed at promoting precision medicine initiatives. Formerly known as Strata Oncology Research, Inc., the company rebranded in 2016 and has been incorporated since 2015.

Cardiac Dimensions, Inc. is a medical device company focused on developing innovative minimally invasive treatments for heart failure and associated cardiovascular issues. Founded in 2000 and headquartered in Kirkland, Washington, with additional operations in Sydney, Australia, and Offenbach, Germany, the company is known for its Carillon Mitral Contour System. This permanent implant is designed specifically for the treatment of functional mitral regurgitation, utilizing a catheter-based approach to reshape the mitral valve and effectively reduce regurgitation. By providing a non-surgical option for patients, Cardiac Dimensions aims to improve outcomes for those suffering from heart-related conditions.

Ebb Therapeutics, Inc. is a company specializing in the development of a regional cerebral thermal therapy (RCTT) device aimed at addressing insomnia and sleep disorders. It offers the Ebb Insomnia Therapy, which is a drug-free solution designed to help individuals improve their sleep quality. Founded in 2008 and originally known as Cereve, Inc., the company is headquartered in Pittsburgh, Pennsylvania. Ebb Therapeutics focuses on innovative therapeutic approaches to enhance sleep health without the reliance on pharmaceuticals.

nVision Medical Corporation is a privately-held medical device company based in Saratoga, California, focused on advancing women's health innovation. Established in 2009, the company specializes in developing devices to assess and treat female infertility resulting from fallopian tube dysfunction. nVision's products are designed not only to detect conditions such as ovarian cancer and tube blockage but also to address the challenges faced in diagnosing and treating issues within the female reproductive tract. By concentrating on these critical areas, nVision aims to improve clinical outcomes and enhance the overall health of women. As of 2018, nVision Medical operates as a subsidiary of Boston Scientific Corporation.

SI-BONE, Inc. is a medical device company based in Santa Clara, California, that specializes in the development and commercialization of implantable devices for surgical treatment of sacropelvic anatomy. Founded in 2008, the company offers a range of patented titanium implants, including the iFuse system, which is designed for the minimally invasive fusion of the sacroiliac joint to alleviate dysfunction that leads to lower back pain. The iFuse implant procedure is noted for its reduced invasiveness and efficiency compared to traditional open fusion methods. In addition to the iFuse system, SI-BONE develops other products such as iFuse-3D, iFuse-TORQ, and iFuse Bedrock Granite, which address various conditions related to sacroiliac joint dysfunction, spinal deformity, and pelvic trauma. The company operates both in the United States and internationally.

Strata Oncology, Inc. is a precision oncology company focused on enhancing cancer care by facilitating access to precision medicine clinical trials and expediting drug approval processes. Based in Ann Arbor, Michigan, the company develops a comprehensive precision oncology platform that supports routine testing and efficient use of molecular data. Strata's offerings include The Strata Trial, a genomic testing program for systematic precision oncology implementation, and StrataNGS, a targeted assay for sequencing DNA and RNA from biopsies. Additionally, StrataPOINT integrates electronic medical record histories with molecular profiling to ensure eligible patients are tested and considered for trial enrollment. The company features a portfolio of pharma-sponsored therapeutic protocols, known as Strata Partnered Trials, aligned to specific biomarkers. Strata also operates The Strata Lab, a cancer sequencing facility, and maintains the Strata Precision Oncology Network, a collaborative entity aimed at promoting precision medicine initiatives. Formerly known as Strata Oncology Research, Inc., the company rebranded in 2016 and has been incorporated since 2015.

ArborMetrix, Inc. is a data analytics company that focuses on enhancing outcomes and measuring value within the healthcare sector. Founded in 2011 and based in Ann Arbor, Michigan, the company offers a suite of technology solutions that include data collection and integration, rigorous performance measurement, and analytics. ArborMetrix's platform provides essential tools such as EpisodeMetrix for cost analysis of healthcare episodes, RegistryMetrix for developing specialized clinical registries, and SurgicalMetrix for analyzing surgical performance. Their services aim to provide actionable insights that enable hospitals, health plans, physician organizations, and specialty societies to optimize financial performance, improve clinical outcomes, and support value-based reimbursement. Additionally, ArborMetrix offers solutions for clinical quality improvement, patient engagement, and post-market surveillance, serving a diverse range of clients within the U.S. healthcare landscape.

Cardiac Dimensions, Inc. is a medical device company focused on developing innovative minimally invasive treatments for heart failure and associated cardiovascular issues. Founded in 2000 and headquartered in Kirkland, Washington, with additional operations in Sydney, Australia, and Offenbach, Germany, the company is known for its Carillon Mitral Contour System. This permanent implant is designed specifically for the treatment of functional mitral regurgitation, utilizing a catheter-based approach to reshape the mitral valve and effectively reduce regurgitation. By providing a non-surgical option for patients, Cardiac Dimensions aims to improve outcomes for those suffering from heart-related conditions.

Cardiac Dimensions, Inc. is a medical device company focused on developing innovative minimally invasive treatments for heart failure and associated cardiovascular issues. Founded in 2000 and headquartered in Kirkland, Washington, with additional operations in Sydney, Australia, and Offenbach, Germany, the company is known for its Carillon Mitral Contour System. This permanent implant is designed specifically for the treatment of functional mitral regurgitation, utilizing a catheter-based approach to reshape the mitral valve and effectively reduce regurgitation. By providing a non-surgical option for patients, Cardiac Dimensions aims to improve outcomes for those suffering from heart-related conditions.

Adavium Medical is a medical equipment and diagnostics company based in São Paulo, Brazil, established in 2011. The company focuses on commercializing an innovative portfolio of medical devices and diagnostic products, representing leading international manufacturers. With a workforce of over 300 employees, Adavium Medical operates a fully-integrated commercial platform that adheres to high standards. It boasts the largest customer base in Brazil, serving more than 2,500 clients in both premium and long-tail segments of the medical equipment and diagnostics market. This extensive reach significantly surpasses that of typical distributors and multinational companies in the region, positioning Adavium Medical as a key player in a fragmented industry.

ArborMetrix, Inc. is a data analytics company that focuses on enhancing outcomes and measuring value within the healthcare sector. Founded in 2011 and based in Ann Arbor, Michigan, the company offers a suite of technology solutions that include data collection and integration, rigorous performance measurement, and analytics. ArborMetrix's platform provides essential tools such as EpisodeMetrix for cost analysis of healthcare episodes, RegistryMetrix for developing specialized clinical registries, and SurgicalMetrix for analyzing surgical performance. Their services aim to provide actionable insights that enable hospitals, health plans, physician organizations, and specialty societies to optimize financial performance, improve clinical outcomes, and support value-based reimbursement. Additionally, ArborMetrix offers solutions for clinical quality improvement, patient engagement, and post-market surveillance, serving a diverse range of clients within the U.S. healthcare landscape.

BAROnova, Inc. is a clinical-stage medical-device company founded in 2006 and headquartered in Goleta, California. The company specializes in developing non-surgical, non-pharmacologic devices aimed at inducing weight loss. Its primary product, the TransPyloric Shuttle, is a device that is inserted into the stomach through the mouth using a straightforward endoscopic procedure. This device is designed to enhance the sensation of fullness by causing the stomach to fill up faster and remain full longer, while also delaying gastric emptying. Through its innovative approach, BAROnova seeks to provide patients with effective tools for weight management without the need for surgery.

Tangent Medical Technologies, a development stage medical device company, was founded in Ann Arbor in 2009 based on technology exclusively licensed from the University of Michigan's Medical Innovation Center. The Company's mission is to improve infusion therapy for patients and healthcare workers with its proprietary, intravenous catheters and associated products. Tangent is led by an experienced, successful management team and the original inventors of the technology. The Company expects to begin generating commercial revenues from its lead product, the NovaCath™ Closed IV Catheter System, in 2012.

Tangent Medical Technologies, a development stage medical device company, was founded in Ann Arbor in 2009 based on technology exclusively licensed from the University of Michigan's Medical Innovation Center. The Company's mission is to improve infusion therapy for patients and healthcare workers with its proprietary, intravenous catheters and associated products. Tangent is led by an experienced, successful management team and the original inventors of the technology. The Company expects to begin generating commercial revenues from its lead product, the NovaCath™ Closed IV Catheter System, in 2012.

Sonitus Medical Inc. is a privately held medical device company based in San Mateo, California, focused on delivering innovative hearing solutions for patients with hearing challenges. The company specializes in bone conduction hearing devices and markets the SoundBite Hearing System, which is recognized as the world's first non-invasive and removable hearing solution that transmits sound through the teeth. This nearly invisible in-the-mouth hearing system is designed to address single-sided deafness and conductive hearing loss, providing a simple and non-surgical alternative for patients. The device is currently FDA cleared as a prosthetic for these specific conditions. Sonitus Medical aims to expand its technology to include treatments for mixed hearing loss and tinnitus, as well as applications in consumer and covert communications. Founded in 2006, Sonitus Medical is emerging as a leader in the field of hearing solutions.

Uptake Medical specializes in developing innovative medical technologies aimed at treating lung diseases. The company's flagship product, InterVapor™, is an endoscopic lung volume reduction therapy designed specifically for individuals with severe emphysema. This unique approach leverages the body’s natural healing processes and does not introduce any foreign materials into the lungs. Clinical studies have shown that InterVapor™ can lead to significant improvements in patients' breathing function, exercise capacity, and overall quality of life.

CerviLenz is a new, disposable device that measure vaginal cervical length during a speculum exam. Cervical length is a powerful predictor of preterm birth risk and influences patient management decisions. CerviLenz gives clinicians an immediate, reliable method for measuring the cervix at the point of care. CerviLenz is manufactured and distributed by Cervilenz Inc. headquartered in Chagrin Falls, Ohio.

Tangent Medical Technologies, a development stage medical device company, was founded in Ann Arbor in 2009 based on technology exclusively licensed from the University of Michigan's Medical Innovation Center. The Company's mission is to improve infusion therapy for patients and healthcare workers with its proprietary, intravenous catheters and associated products. Tangent is led by an experienced, successful management team and the original inventors of the technology. The Company expects to begin generating commercial revenues from its lead product, the NovaCath™ Closed IV Catheter System, in 2012.

CerviLenz is a new, disposable device that measure vaginal cervical length during a speculum exam. Cervical length is a powerful predictor of preterm birth risk and influences patient management decisions. CerviLenz gives clinicians an immediate, reliable method for measuring the cervix at the point of care. CerviLenz is manufactured and distributed by Cervilenz Inc. headquartered in Chagrin Falls, Ohio.

NxThera, founded in 2008 and headquartered in Maple Grove, Minnesota, specializes in the development of medical technologies for treating endourological conditions. The company's core technology involves convective water vapor energy, designed to deliver minimally invasive, thermal therapy for conditions such as benign prostatic hyperplasia (BPH), which affects over 32 million men in the U.S. As of April 30, 2018, NxThera operates as a subsidiary of Boston Scientific Corporation.

Accuri Cytometers was founded to address a compelling need: life scientists love the rapid cell-by-cell analysis capability of flow cytometers, but too few have a flow cytometer in their lab. The barriers for most researchers include cost of the instrument, complexity of the software, effort required for maintenance, and the large amount of bench space required for the instrument. As a result, the company is looking to develop affordable and robust cytometers.

Uptake Medical specializes in developing innovative medical technologies aimed at treating lung diseases. The company's flagship product, InterVapor™, is an endoscopic lung volume reduction therapy designed specifically for individuals with severe emphysema. This unique approach leverages the body’s natural healing processes and does not introduce any foreign materials into the lungs. Clinical studies have shown that InterVapor™ can lead to significant improvements in patients' breathing function, exercise capacity, and overall quality of life.

CardioMEMS is a medical device company specializing in wireless monitoring solutions for severe chronic cardiovascular conditions. Their proprietary technology involves miniature sensors implanted via minimally invasive procedures, transmitting vital data like cardiac output, blood pressure, and heart rate to enhance patient management, particularly for heart failure, hypertension, and aneurysms.

CardioMEMS is a medical device company specializing in wireless monitoring solutions for severe chronic cardiovascular conditions. Their proprietary technology involves miniature sensors implanted via minimally invasive procedures, transmitting vital data like cardiac output, blood pressure, and heart rate to enhance patient management, particularly for heart failure, hypertension, and aneurysms.

Accuri Cytometers was founded to address a compelling need: life scientists love the rapid cell-by-cell analysis capability of flow cytometers, but too few have a flow cytometer in their lab. The barriers for most researchers include cost of the instrument, complexity of the software, effort required for maintenance, and the large amount of bench space required for the instrument. As a result, the company is looking to develop affordable and robust cytometers.

CerviLenz is a new, disposable device that measure vaginal cervical length during a speculum exam. Cervical length is a powerful predictor of preterm birth risk and influences patient management decisions. CerviLenz gives clinicians an immediate, reliable method for measuring the cervix at the point of care. CerviLenz is manufactured and distributed by Cervilenz Inc. headquartered in Chagrin Falls, Ohio.

BAROnova, Inc. is a clinical-stage medical-device company founded in 2006 and headquartered in Goleta, California. The company specializes in developing non-surgical, non-pharmacologic devices aimed at inducing weight loss. Its primary product, the TransPyloric Shuttle, is a device that is inserted into the stomach through the mouth using a straightforward endoscopic procedure. This device is designed to enhance the sensation of fullness by causing the stomach to fill up faster and remain full longer, while also delaying gastric emptying. Through its innovative approach, BAROnova seeks to provide patients with effective tools for weight management without the need for surgery.

HandyLab is a medical technology company that develops and manufactures molecular diagnostic assays and automation platforms The company’s proprietary platform reduces the time, cost, and complexity of testing while improving the quality of results. Using patented real-time microfluidic PCR technology, its products are positioned to decentralize nucleic acid testing. HandyLab was founded in 2000 and is based in Ann Arbor, Michigan. It was acquired by Becton, Dickinson and Company in 2009.

Accuri Cytometers was founded to address a compelling need: life scientists love the rapid cell-by-cell analysis capability of flow cytometers, but too few have a flow cytometer in their lab. The barriers for most researchers include cost of the instrument, complexity of the software, effort required for maintenance, and the large amount of bench space required for the instrument. As a result, the company is looking to develop affordable and robust cytometers.

Mirabilis Medical, Inc., established in 2004 and headquartered in Bothell, Washington, specializes in the design, development, manufacturing, distribution, installation, and servicing of ultrasound devices for non-invasive treatment of uterine fibroids. Their proprietary technology employs high-resolution ultrasound imaging for precise localization and non-invasive ablation of targeted tissue, eliminating the need for incisions or punctures.

KFx Medical specializes in the development and manufacturing of advanced soft tissue fixation implants specifically designed for orthopedic sports medicine. The company creates innovative products that facilitate tissue fixation, allowing for direct placement into bone, with or without sutures. These implants are utilized in various orthopedic surgical procedures, enabling surgeons to effectively reattach tissue in areas such as the shoulder, knee, foot, and ankle. KFx Medical collaborates with leading orthopedic surgeons to refine its technology and enhance surgical outcomes for patients.

Accuri Cytometers was founded to address a compelling need: life scientists love the rapid cell-by-cell analysis capability of flow cytometers, but too few have a flow cytometer in their lab. The barriers for most researchers include cost of the instrument, complexity of the software, effort required for maintenance, and the large amount of bench space required for the instrument. As a result, the company is looking to develop affordable and robust cytometers.

Inogen is a medical technology company specializing in oxygen therapy solutions for patients with chronic respiratory conditions. The company designs and manufactures portable oxygen concentrators, with its flagship product being the Inogen One system, which offers a lightweight and convenient alternative to traditional stationary oxygen concentrators and oxygen tanks. Inogen sells its products to home medical equipment providers and directly rents devices to patients, primarily generating its revenue in the United States. Additionally, the company distributes its products internationally through partnerships with large gas companies and home oxygen providers. Inogen's mission is to enhance the freedom and independence of oxygen therapy users by providing innovative and user-friendly products and services.

Uptake Medical specializes in developing innovative medical technologies aimed at treating lung diseases. The company's flagship product, InterVapor™, is an endoscopic lung volume reduction therapy designed specifically for individuals with severe emphysema. This unique approach leverages the body’s natural healing processes and does not introduce any foreign materials into the lungs. Clinical studies have shown that InterVapor™ can lead to significant improvements in patients' breathing function, exercise capacity, and overall quality of life.

BAROnova, Inc. is a clinical-stage medical-device company founded in 2006 and headquartered in Goleta, California. The company specializes in developing non-surgical, non-pharmacologic devices aimed at inducing weight loss. Its primary product, the TransPyloric Shuttle, is a device that is inserted into the stomach through the mouth using a straightforward endoscopic procedure. This device is designed to enhance the sensation of fullness by causing the stomach to fill up faster and remain full longer, while also delaying gastric emptying. Through its innovative approach, BAROnova seeks to provide patients with effective tools for weight management without the need for surgery.

KFx Medical specializes in the development and manufacturing of advanced soft tissue fixation implants specifically designed for orthopedic sports medicine. The company creates innovative products that facilitate tissue fixation, allowing for direct placement into bone, with or without sutures. These implants are utilized in various orthopedic surgical procedures, enabling surgeons to effectively reattach tissue in areas such as the shoulder, knee, foot, and ankle. KFx Medical collaborates with leading orthopedic surgeons to refine its technology and enhance surgical outcomes for patients.

Founded in 1998 by Dr. Victor Strecher, HealthMedia specializes in developing scalable behavior change interventions that emulate the effectiveness of health coaching without the need for a live coach. The company creates innovative programs tailored for health and wellness, disease management, behavioral health, and medication compliance. HealthMedia collaborates with pharmaceutical firms and medical device manufacturers to address various health challenges, including drug and alcohol addiction, mental illness, cardiovascular diseases, hypertension, and HIV/AIDS. Through its unique methodology and technology, HealthMedia delivers impactful outcomes comparable to traditional health coaching, making it a leader in the field of digital health solutions.

Accuri Cytometers was founded to address a compelling need: life scientists love the rapid cell-by-cell analysis capability of flow cytometers, but too few have a flow cytometer in their lab. The barriers for most researchers include cost of the instrument, complexity of the software, effort required for maintenance, and the large amount of bench space required for the instrument. As a result, the company is looking to develop affordable and robust cytometers.

CardioMEMS is a medical device company specializing in wireless monitoring solutions for severe chronic cardiovascular conditions. Their proprietary technology involves miniature sensors implanted via minimally invasive procedures, transmitting vital data like cardiac output, blood pressure, and heart rate to enhance patient management, particularly for heart failure, hypertension, and aneurysms.

NeoGuide Systems Inc. is a developer of robotic endoscopic technology specifically designed for natural orifice transluminal endoscopic surgery (NOTES). Founded in 2000 and based in San Jose, California, the company focuses on creating advanced solutions for medical procedures, particularly in colonoscopy applications. Its innovative technology aims to enhance the visualization and delivery of therapies within the body, thereby improving access to abdominal and thoracic cavities. NeoGuide is positioned at the forefront of a transformative approach in minimally invasive surgery, contributing to the evolution of medical practices in the field.