Founded in Louisville, Kentucky, Render Capital is a venture capital firm investing in early-stage companies across the Midwest and South. The firm focuses on sectors such as healthcare, healthtech, supply chain, logistics, advanced manufacturing, e-commerce, consumer packaged goods, B2B SaaS, food and beverage.

Founded in 2004, Bluegrass Angels is an angel investment group based in Lexington, Kentucky. It provides capital investments and mentoring to early-stage startup companies across various sectors, including healthcare, agriculture, industrial chemicals, manufacturing, biotech, fintech, media, and information technology.

Connetic Ventures is a venture capital firm based in Covington, Kentucky. Established in the mid-2010s, it provides capital and strategic support to early-stage startups, often partnering with other venture capital firms and angel syndicates for seed investments. The firm targets software, data, fintech, and consumer sectors across North America, including the United States and Canada.

Access Ventures, established in 2013 and headquartered in Louisville, Kentucky, is a private operating foundation and impact investment firm. It works to foster systemic change in communities, aiming to create an inclusive and creative economy that benefits all people. The firm invests across various asset classes and sectors, supporting organizations of all sizes, from startups to enterprises, in the private, public, and social sectors. Its investment portfolio spans creative arts, innovative finance, strategic real estate, and technology for social good. Access Ventures also provides micro and secured loans, grants, equity, and debt to support its mission.

Advantage Capital Partners is a United States‑based venture capital firm that provides growth equity, debt, and mezzanine financing to small and mid‑market companies, with a focus on underserved communities and state and local economic development. The firm invests across sectors including manufacturing, technology, business services, life sciences, and energy, and also supports real estate development projects with equity and debt. It typically makes initial investments ranging roughly from half a million to ten million in companies with modest sales, and may participate in larger follow‑on rounds or co‑invest with other firms. It uses senior debt, mezzanine debt, subordinated loans, and government‑guaranteed lending, and often pursues equity positions through preferred shares or convertible notes. Advantage Capital operates nationwide in the United States, with roots in New Orleans and offices in multiple states, and has backed thousands of jobs and housing projects as part of its mission to expand inclusive economic growth.

Poplar Ventures is a Louisville, Kentucky-based venture capital firm and business advisor that invests in early- to growth-stage cloud-based software companies serving business customers across the United States and Middle America, offering strategic guidance to help them scale.

Meritus Ventures is a venture capital firm based in London, Kentucky. It makes equity investments in expansion-stage private companies, with a focus on rural areas of central and southern Appalachia. The firm targets opportunities in information technology, industrials, and technology, media, and telecommunications sectors, and its activity spans across Tennessee, Kentucky, Arkansas, and Appalachian counties in Ohio, West Virginia, Virginia, North Carolina, South Carolina, Georgia, Alabama, and Mississippi. It may provide operational support to portfolio companies.

The Southern Appalachian Fund is a $12.5 million venture capital firm based in Oak Ridge, Tennessee, with an additional office in London, Kentucky. It invests in early and expansion-stage companies operating in the interactive home entertainment, manufacturing, technology, and software sectors, with a focus on small businesses in southern Appalachia, particularly in Kentucky, Tennessee, and the Appalachian counties of Georgia, Alabama, and Mississippi. The fund typically invests between $200,000 and $600,000 in its portfolio companies, often leading investment syndicates or co-investing with other institutional investors and seasoned angel investors. It seeks to generate market-rate returns for its investors while promoting shared and sustainable business growth and wealth creation in its target region. The fund's mission is to provide not only equity capital but also operational assistance, active board participation, and mentoring to its portfolio companies.

RZN8 Capital is an early-stage investment firm based in Louisville, Kentucky, established in 2019. The firm focuses on investing in mobile-based consumer technologies, aiming to support innovative companies in this sector. Through its investments, RZN8 Capital seeks to foster the growth of emerging technologies that enhance consumer experiences and engagement.

Established in 2019 with headquarters in Louisville, Kentucky, The 6ixth Event is a venture capital firm focusing on investments in decentralized technology and fintech sectors.

Founded in 2009, TriStar Health Partners is a venture capital firm specializing in early-stage investments, primarily focusing on healthcare innovation. It invests in life sciences, diagnostics, medical devices and technologies, IT, and healthcare services companies, with a preference for those based in the Southeast United States, particularly Tennessee.

Lunsford Capital is a private investment firm based in Louisville, Kentucky, founded in 2000 and led by Bruce Lunsford, who previously served as the founder and Chairman and CEO of a prominent healthcare real estate investment company. The firm focuses on venture capital investments across several sectors, including healthcare, technology, entertainment, and real estate, aiming to identify and support innovative companies within these industries.

Blue Equity is a private equity firm founded in 2004, headquartered in Louisville, Kentucky. It invests in diverse industries such as distribution, talent representation, hospitality, media, finance, healthcare, and real estate. The firm focuses on investments with solid developmental potential, typically ranging from $0.1 million to $50 million. Blue Equity seeks operating control and prefers majority stakes.

Founded in 1999, OCA Ventures is a Chicago-based venture capital firm focusing on early-stage investments primarily in technology and highly-scalable services businesses. The firm's investment focus areas include digital health, fintech, consumer software, and enterprise software.

Founded in 2001, ScOp Venture Capital is a Santa Barbara-based venture capital firm focusing on early-stage companies. It invests primarily in software, SaaS, AI, and e-commerce sectors across the U.S., seeking scalable opportunities that meet fundamental consumer or business needs. The firm partners with passionate founders, taking a long-term perspective and aiming for profound impact.

Leader Ventures is a private investment firm based in Palo Alto, California, specializing in providing debt and equity financing to a diverse portfolio of early and late-stage private companies. Established in 2005, the firm primarily operates in the United States and focuses on sectors such as information technology, life sciences, and clean technology. Leader Ventures offers venture loans to companies that may not qualify for traditional debt financing, utilizing various loan structures tailored to the developmental stages of the businesses. The firm's investment team, which has extensive experience in lending, investing, and managing startups, seeks to support high-growth potential companies by financing specific equipment purchases and providing growth capital. With offices in Menlo Park and San Francisco, Leader Ventures is well-positioned to identify and nurture promising investment opportunities.

Equilibrium Capital is a global platform offering sustainability-focused real asset strategies. Its core principle is sustainability, applied across sectors such as renewable energy, green real estate, and sustainable agriculture.

Ben Franklin Technology Partners of Southeastern Pennsylvania is a technology-focused capital provider based in Philadelphia, founded in 1982 to advance the region's technology community. The organization funds and supports technology companies across Pennsylvania, especially in information technology, health, and physical sciences, investing substantial capital in early-stage and established ventures. It has invested over 170 million dollars in more than 1,750 regional technology companies and has launched university-industry partnerships to translate scientific discoveries into commercial products, while seeding regional initiatives that strengthen the entrepreneurial ecosystem and create jobs.

Founded in 2017, SeedFunders is a venture capital firm specializing in pre-seed and early-stage investments. Based in St. Petersburg, Florida, they focus on investing in technology startups across various sectors throughout the state.

MissionOG is a Philadelphia-based venture capital and private equity firm that partners with high-growth business-to-business companies in fintech, financial services, data platforms, and software. It provides capital and leverages a broad network of industry experts to accelerate growth and guide portfolio companies toward strategic outcomes, including acquisitions. Founded in 2012, MissionOG is led by a team with experience in building and scaling companies through multiple growth stages. The firm focuses on early-stage and growth investments in sectors where it has operating expertise, including financial services, payments, software, and data-enabled technologies.

Founded in 1999, Origin Ventures is an early-stage venture capital firm investing in high-growth software, marketplace, and consumer businesses. With multiple funds ranking in the top 5% on realized performance, they have facilitated successful exits such as Grubhub. The firm typically invests $500K to $8M in Series A rounds for companies demonstrating product-market fit.

Founded in 2015, Stadia Ventures is a venture capital firm focused on sports and esports industries. Based in St. Louis with operations expanded to Frisco/Dallas, the company invests in early-stage startups, providing them with business development bootcamps, mentorship, and networking opportunities.

Headquartered in San Francisco with offices globally, Citi Ventures explores, incubates, and invests in innovative ideas across fintech, data analytics, commerce, security, marketing, property tech, distributed ledger technology, and digital assets. It collaborates with Citi colleagues, clients, and the broader innovation community to drive discovery of new value.

Lightship Capital is a venture capital firm focused on investing in early-stage startups, particularly those led by underrepresented minorities and located outside of major tech hubs like Silicon Valley, New York City, and Boston. The company concentrates its investments in sectors such as artificial intelligence, consumer packaged goods, sustainability, e-commerce, healthcare, and real estate.

Founded in 2017, Halogen Ventures is a Los Angeles-based venture capital firm focused on investing in early-stage consumer technology startups led by women. The firm supports founders throughout their lifecycle, providing hands-on assistance with networking, brand exposure, talent acquisition, follow-on funding, and strategic growth.

Mucker Capital is a California-based venture capital firm that funds early-stage technology companies, specializing in Internet software, services and media with a focus on Enterprise, fintech, B2B and consumer products. It targets pre-seed to Series A rounds and seeks opportunities outside Silicon Valley, particularly in Los Angeles and broader Southern California as well as other underfunded ecosystems in the United States and Canada. The firm typically invests between $0.25 million and $1 million per deal and operates MuckerLab, an accelerator program whose duration ranges from three to twenty-four months to help portfolio companies grow. The firm is headquartered in Santa Monica and maintains an additional office in Nashville.

Founded in 2017, Stout Street Capital is a Denver-based venture capital firm investing in early-stage technology companies. They focus on sectors such as software, fintech, advanced materials, robotics, and artificial intelligence, with an emphasis on underserved markets, particularly the Rocky Mountain region.

Revolution is a Washington, D.C.–based venture capital firm founded in 2005 by Steve Case, with an additional office in San Francisco. It backs technology-enabled startups that disrupt traditional industries and supports both early-stage and growth-stage companies, often taking leadership roles in financings and serving on boards. The firm operates a family of funds, including Revolution Ventures and Revolution Growth, and seeks opportunities across sectors such as consumer internet, software and services, media, financial services, healthcare, and other technology-enabled businesses. It emphasizes geography, aiming to back high-potential ventures in regions beyond traditional hubs by pairing capital with hands-on involvement and broad entrepreneurial networks.

Founded in 2017, Conductive Ventures is a venture capital firm based in Palo Alto, California. It invests in expansion-stage companies focused on enterprise software and hardware, deploying $100M into post-product companies with early customer success. The team works closely with portfolio companies to accelerate revenue growth through strategic partnerships.

Founded in 2007 and headquartered in Chicago, Seyen Capital is a venture capital firm focusing on growth-stage investments. It primarily targets information technology and software companies based in major U.S. cities, typically investing between $5 million to $15 million. The firm prefers to partner with management teams and co-investors, often taking a seat on the Board of Directors.

High Alpha, headquartered in Indianapolis, Indiana, operates as a B2B SaaS venture studio and early-stage investor. It conceives, launches, and scales B2B SaaS companies through High Alpha Studio, offering a blend of services including design, finance, talent, marketing, branding, and go-to-market support, alongside capital to accelerate growth toward enterprise-scale outcomes.

Founded in 2011, Hyde Park Venture Partners is a Chicago-based venture capital firm specializing in early-stage investments. It focuses on high-growth technology startups across the Midwest, with an emphasis on software and tech-enabled businesses. The firm typically invests between $0.1 million to $2.5 million, co-investing with Hyde Park Angels. They actively mentor portfolio companies, supporting product development, business strategy, financing, and exit strategies.

Founded in 2000, Aisling Capital is a New York-based investment firm focusing on mid-market and growth-oriented investments in life sciences, healthcare, and technology companies across the United States and Western Europe. The company aims to support leading global healthcare companies commercializing new products driven by biotechnology advancements.

Battery Ventures is a technology-focused investment firm founded in 1983 and based in Boston, Massachusetts. It engages in venture capital and private equity investments in technology companies, with emphasis on software (including application and infrastructure software), IT infrastructure technologies, consumer internet and mobile services, industrial technologies, and life science tools. The firm seeks to back category-defining businesses with potential for scalable growth, often supporting companies through multiple stages and across select global regions.

Network VC is a venture capital firm established in 2019 and located in Menlo Park, California. The firm focuses on investing in startups across various sectors, leveraging a robust ecosystem to access a diverse pool of investment opportunities. This ecosystem is primarily built through initiatives like Unicorn Battles and CUP Startup, which create a significant funnel of startups. By tapping into this extensive network, Network VC aims to identify and support high-potential startups, thereby enhancing its investment success.

Founded in 2021, Ludus is a venture capital firm based in Istanbul, Turkey. It specializes in investing in and supporting early-stage gaming startups globally, providing strategic guidance, funding, and operational support.

MariMed, a multi-state cannabis operator, develops and manages cultivation, production, and retail facilities. It operates brands including Betty's Eddies, Bubby's Baked, Vibations, InHouse, and Nature's Heritage. The company also provides advisory services to operators, including design, development, operations, financing, licensing assistance, real estate site selection, compliance, systems design, managed services for cultivation, production, distribution, business planning, financial modeling, community outreach, education, facility buildout, and business acceleration.

Oak HC/FT is a venture and growth equity investment firm specializing in healthcare information services and financial technology. It supports portfolio companies with strategic counsel, board-level participation, and access to a broad network of industry leaders to drive transformation in these sectors. The firm, based in Stamford, Connecticut, operates within the Oak Investment Partners family, leveraging sector-specific expertise from Oak's healthcare and fintech teams to build and scale innovative businesses.

White Star Capital is a global multi-stage technology investment firm and venture platform headquartered in New York, with a presence across North America, Europe and Asia. It backs exceptional entrepreneurs building ambitious, internationally scalable tech companies, helping portfolio founders scale their businesses from Series A onwards through its experience, networks and value-add support. The firm invests across software, information technology and digital assets, operating a core venture program and a dedicated digital asset strategy that backs crypto networks and blockchain-enabled businesses. Its offices span New York, London, Montreal, Toronto, Paris, Tokyo and Hong Kong, enabling it to partner with founders to expand internationally.

Scientific Health Development Ltd. is a boutique investment firm based in Dallas, Texas, founded in 2006. The company specializes in early-stage investments, focusing on innovative healthcare-related technologies, products, and services within the health, science, medical, and wellness sectors. It typically invests up to $0.2 million in each portfolio company, often before their products are ready for public availability. Scientific Health Development aims to support the growth of promising ventures in the U.S. healthcare landscape while allowing its investors the opportunity to co-invest in these emerging companies.

Longitude Capital is a California-based investment firm focused on venture growth in life sciences, including biotechnology and medical technology companies. Founded in 2006, it targets both privately held and publicly traded life science companies and pursues a balanced portfolio of clinical-stage and commercial-stage assets with the potential for value creation within three to five years. The firm identifies opportunities through its broad industry network and thematic research into emerging therapeutic areas or sub-sectors, and uses a range of investment structures including traditional venture capital, asset spin-outs, recapitalizations, PIPEs, open market purchases, royalties, and other equity-linked instruments. It maintains offices in Menlo Park, Greenwich, and Boston and operates as a registered investment adviser.

LaunchCapital, established in 2008, is a venture capital firm headquartered in New Haven, Connecticut, with additional offices in Boston, New York, and San Francisco. The company invests in early-stage startups, focusing on seed rounds with investments typically ranging from $50,000 to $150,000. LaunchCapital supports entrepreneurs across various sectors, including commerce, marketplace, consumer, media, entertainment, enterprise software, emerging tech, data, finance, healthcare, and medical technology. The firm employs two distinct investment strategies: LaunchCapital Ventures, which follows a traditional equity model for high-growth opportunities, and LaunchCapital Small Business, which offers a blend of equity and debt financing for businesses with linear growth expectations and local or regional reach.

Pamoja Capital is a private investment firm founded in 2006 by John McCall MacBain and colleagues. Based in Luxembourg, it pursues long-term, socially responsible investments across sectors including education, life sciences and healthcare, information technology, media and communications, real estate and environmental services. The firm engages across growth stages through buyouts, management buyouts and growth equity, seeking opportunities worldwide across Europe, North America, Asia, Oceania and the Middle East. It emphasizes investments with sustainable cash flow and leverages operating experience to support portfolio companies, aiming to deliver enduring value and competitive advantage through a patient, long-term approach.

Tiger Global Management is a New York based investment firm that manages public and private market strategies to pursue technology-driven growth opportunities worldwide. Founded in 2001 by Charles (Chase) Coleman, the firm invests in leading global companies across various industries, with a particular emphasis on technology-enabled growth. In public markets it employs long/short and growth strategies, while in private markets it targets opportunities from early to late stage. The firm operates globally, including the United States, China, India, Latin America, and Eastern Europe, and works with portfolio companies across their lifecycle to drive long-term value.

Founders Fund is a San Francisco-based venture capital firm that backs science and technology companies across multiple stages, from seed to late-stage. It pursues transformative technologies and follows a founder-friendly investment approach that provides substantial support with minimal interference. The firm invests in ventures solving difficult problems across sectors such as aerospace and transportation, artificial intelligence, advanced computing, energy, healthcare, biotechnology, cybersecurity, fintech, consumer internet, software, robotics, and related technology fields. It has backed notable companies early, including SpaceX, Palantir, and Facebook, reflecting a history of partnering with ambitious founders to scale breakthrough technologies.

Founded in 1997, Endeavor is a global non-profit organization dedicated to supporting high-impact entrepreneurs. With operations in nearly 40 countries, Endeavor's network comprises over 2,000 entrepreneurs who have created more than 3.9 million jobs and generated revenues exceeding $28 billion.

Founded in 2020, Narya Capital is an early-stage venture capital firm focused on investing in technology and science sectors to address critical problems facing America. The firm supports founders and companies pioneering bold steps forward in areas such as healthcare, agriculture, defense, and financial services.

S2G Ventures is a Chicago-based, multi-stage investment firm focused on fostering innovation across food and agriculture, oceans, and energy. Founded in 2014, it targets late-stage venture and growth investments and maintains a portfolio spanning seed, venture, and growth rounds. The firm backs entrepreneurs delivering market-driven solutions that transform food systems and related sectors, including ingredients, infrastructure and logistics, food safety technology, retail and consumer brands, as well as opportunities in ocean and energy domains. Its objective is to catalyze healthier, sustainable, and locally sourced food systems through investments that cover agricultural products, logistics, and consumer offerings.

Southeast Interactive Technology Funds was a venture capital firm established in 1995 and based in Morrisville, North Carolina, with an additional office in Redwood City, California. The firm specialized in investing in early, mid, and late-stage companies primarily within the information technology and communications sectors. Its investment focus included enterprise management and software, Internet infrastructure, telecommunications, and business services. The firm was particularly interested in innovations related to energy applications, advancements in computing efficiency, and ideas that enhanced data utility for businesses and consumers. Southeast Interactive Technology Funds aimed to lead or co-lead initial investments, primarily targeting companies based in the Southeastern United States. The firm was known for its proactive investment approach and strong partnerships with management teams. However, it is now out of business.

BP Ventures is a venture capital firm established in 2007, investing in private technology companies to accelerate innovation across the energy sector. With over $400 million invested across more than 40 entities and over 200 co-investors, BP Ventures focuses on Oil & Gas Value Chain, Low Carbon Technologies & Fuels, and Energy Usage & Trading, delivering near-term business value while backing breakthrough innovations for a sustainable future.