Service Provider Capital is a venture capital firm established in 2014 and based in Colorado. The firm focuses on early-stage investments, notably seed-stage opportunities, and participates as a co-investor in Series A rounds led by institutional venture funds. Its portfolio interests span a broad range of technology sectors, including artificial intelligence, machine learning, blockchain, cybersecurity, e-commerce, education technology, fintech, hardware, information technology, robotics, health, and cannabis.

Caring for Denver Foundation is a new nonprofit formed and supported by overwhelming voter approval to use tax income to fund programs addressing mental health and drug misuse prevention, treatment, rehabilitation, and harm reduction in the City and County of Denver.

Founded in 2007, Foundry Group is a venture capital firm headquartered in Boulder, Colorado. It focuses on early-stage investments in information technology, Internet, and software companies across North America.

The U.S. Department of Energy is a government agency established in 1977, located in Washington, D.C. Its primary mission is to ensure the security and prosperity of the nation by tackling energy, environmental, and nuclear challenges. The Department focuses on promoting transformative scientific and technological solutions to address these issues, thereby supporting the country's energy needs and environmental sustainability.

Rockies Venture Club is a Colorado-based nonprofit organization and angel network focused on economic development through funding and supporting early-stage startups. Founded in 1985 and based in Denver, it educates and connects state, local and national economic development organizations, universities, federal labs, startup organizations, corporate partners, venture capital, angel investors, and entrepreneurs to strengthen startup ecosystems. The club hosts events such as the Angel Capital Summit and Colorado Capital Conferences and maintains a community of more than 150 angel investors active across industries from pre-seed to Series A, with activity spanning North America.

The National Science Foundation is an independent federal agency in the United States that funds and supports research and education in science and engineering. It funds fundamental research and education across all fields of science and engineering and administers non-dilutive funding programs to aid early‑stage technology development, helping translate discoveries into commercially viable products and services. Through grants and fellowships, the NSF supports researchers, educators, and startups, contributing to innovation and U.S. competitiveness. The agency operates with a substantial budget to advance science, engineering, and STEM education nationwide.

Founded in 1999, Access Venture Partners is a venture capital firm based in Denver, Colorado. It specializes in seed and early-stage investments in technology companies across the United States, with a focus on software, cybersecurity, big data, clean technology, SaaS, and new media sectors. The firm typically invests between $0.25 million to $2.5 million per company, seeking to take its portfolio companies public within two to four years.

Founded in 1999, Enhanced Capital Partners is a New York-based investment firm managing over $400 million. It specializes in equity and debt investments for small to mid-sized companies across various sectors, with a focus on healthcare technology systems and TMT industries.

Boomtown Accelerator, established in 2014 and based in Boulder, Colorado, is a startup accelerator that invests in early-stage companies, primarily in the advertising technology, internet, mobile, and healthcare technology sectors. It offers a 12-week program, providing selected teams with $20,000 in seed money, access to office space and amenities, and strategic support from partners and staff. The accelerator also connects startups with expert mentors, alumni network, and potential corporate customers and funding sources. Boomtown's approach is tailored to each company's needs, aiming to help startups transform ideas into profitable, scalable businesses.

FirstMile Ventures is a venture capital firm specializing in seed and early-stage investments, primarily focusing on B2B software and infrastructure technology companies. Based in Colorado Springs with an additional office in Denver, the firm invests across North America but prefers Colorado-based opportunities. Initial investments typically range from $0.05 million to $1.5 million, with provisions for follow-on financing.

Delta Dental of Colorado, established in 1957 and based in Centennial, Colorado, is the state's leading dental benefits provider, exclusively focusing on dental insurance. As a nonprofit organization, it is dedicated to improving oral health in Colorado, with more than half of its earnings reinvested into the local community. The company serves approximately one million members, offering the advantage of local customer service while maintaining access to a national network of dental providers. Through collaborative efforts with partners statewide, Delta Dental of Colorado also provides innovative oral health support to those in need, underscoring its commitment to enhancing community well-being.

Founded in 2013, Matchstick Ventures is a venture capital firm based in Minneapolis, Minnesota. It supports the creation and growth of early-stage technology companies, primarily focusing on seed-stage investments across various sectors such as business products, services, information technology, and TMT.

Boulder Ventures is a venture capital firm based in Boulder, Colorado, founded in 1995. It focuses on early-stage information technology and life sciences companies, investing in areas such as communications software and services, network infrastructure, information management, and biotechnology tools including drug discovery. The firm targets opportunities in Colorado and the Mid-Atlantic region and typically participates in initial investments with potential follow-on capital, often aiming to lead deals in its portfolio companies.

New Enterprise Associates is a venture capital firm founded in 1977 and based in Menlo Park, California, with offices in the United States, India and China. It makes investments across technology and healthcare startups at multiple stages, from seed to growth, including software, cloud, data, internet services, fintech, AI, e-commerce, and enterprise technology, as well as healthcare information technology, life sciences, medical devices, and biopharma. It also considers energy technology and infrastructure opportunities, such as solar, batteries and smart grids. The firm pursues a global approach, with activity in the United States, Asia and other regions, and supports companies through rounds of financing ranging from small to sizable investments as they scale. NEA focuses on building portfolios in software, IT services, consumer technology, and healthcare technology, backing ambitious entrepreneurs across sectors and geographies.

Alumni Ventures Group is a venture capital firm based in Manchester, New Hampshire, with offices across North America. It provides access to venture investing for individual accredited investors, particularly alumni networks, by offering diversified portfolios of venture opportunities and allowing members to invest alongside fellow alumni in ventures led by peers. The firm backs early-stage and later-stage opportunities across technology, consumer, healthcare, financial services, and other sectors, with a sector- and geography-agnostic approach. It typically invests between $10,000 and $3 million per deal and emphasizes the involvement of alumni connections and an institutional lead investor in opportunities. Alumni Ventures also offers focused funds to broaden participation, enabling accredited investors to access venture portfolios diversified by type, sector, stage, and geography. The model aims to democratize access to venture capital while maintaining rigorous selection standards through alumni networks.

Founded in 2005, Iron Gate Capital is a venture capital firm based in Louisville, Colorado. It primarily invests in enterprise technology companies at the early growth stage, with initial investments ranging from $3 to $5 million.

Greenline Ventures is a Denver-based investment firm that operates across capital markets and financial services in the United States. The firm engages in asset management and targets buyout investments within the financial services sector, with a focus on opportunities across the U.S. It also maintains a venture investment arm that backs startups in healthcare, financial technology, big data, clean technology, digital health, food technology, health technology, the Internet of Things, and software as a service, and it pursues impact investments. The firm emphasizes a diversified approach across traditional finance and technology-enabled sectors, aiming to create value for its clients and portfolio companies while supporting sustainable solutions.

Flywheel Ventures, established in 1999, is a venture capital firm headquartered in Santa Fe, New Mexico, with additional offices in Albuquerque, New Mexico, and San Francisco, California. The firm specializes in seed and early-stage investments, focusing on information technology services and physical sciences sectors, including software, semiconductors, and clean technology. Flywheel Ventures primarily invests in companies based in the Midwest, Southwestern, and Rockies regions of the United States, with a particular focus on New Mexico, Colorado, and Arizona, while also considering co-investments in California. The firm typically invests between $0.05 million and $1 million initially, with a 3:1 or greater target reserve for follow-on funding. Flywheel Ventures seeks to address key global challenges in information technology and urban systems, often taking a board seat and investing in syndicates to provide follow-on capital.

Crescendo Capital Partners, established in 2007, is a private equity and venture capital firm headquartered in Centennial, Colorado. The company specializes in growth capital investments, focusing on early and later-stage companies in the lower middle market. Crescendo targets businesses in various sectors, including manufacturing, telecommunications, healthcare, and energy, with a particular focus on the Denver area. The firm typically invests up to $0.5 million in early-stage companies with less than $1 million in revenue and up to $50 million in enterprise value, and up to $100 million in later-stage companies with revenues between $10 million and $100 million. Crescendo seeks to take a significant stake in its portfolio companies, providing them with business expertise, professional networks, and capital resources to drive growth and unlock their full potential.

Right Side Capital Management is a San Francisco-based venture capital firm that focuses on early-stage, pre-seed technology startups in underserved segments of the ecosystem. It invests in a high-volume, capital-efficient portfolio, typically funding rounds of 50,000 to 500,000 and making roughly 75 to 100 investments per year. The firm targets opportunities across the United States and internationally, including Canada, Israel, Australia, New Zealand, and Western Europe, prioritizing companies with scalable products and prudent capital use outside major metro hubs. Since its inception, it has built a broad portfolio across many states. It commits to a fast decision process, often delivering a yes or no within two weeks to help founders establish momentum.

Costanoa Ventures is a California-based independent venture capital firm founded in 2012 that focuses on early-stage technology companies, including seed and Series A rounds. It targets B2B and enterprise-focused opportunities across cloud-based services, data analytics, applications and infrastructure, fintech, security, modern software as a service, big data, and AI-enabled solutions. The firm backs companies at the forefront of enterprise software, developer infrastructure, cybersecurity, and related technologies, helping startups with go-to-market strategy, product-market fit, and long-term growth. Headquartered in Palo Alto with an additional office in San Francisco, Costanoa Ventures supports entrepreneurs building durable, data-driven businesses.

Founded in 2015, FJ Labs is a New York-based venture capital firm focusing on stage-agnostic investments in marketplaces and consumer-facing startups. Their investment range varies from $50,000 to $5,000,000, typically at seed or series A stages.

Unless is a venture capital firm headquartered in Boulder, Colorado, that funds companies operating in industrial systems and related technologies, pursuing impact-oriented investments that combine financial returns with positive systemic change, partnering with entrepreneurial teams across private and public markets and drawing on a network of experts to provide strategic guidance and resources, and supporting companies at the frontiers of artificial intelligence, robotics, information technology, manufacturing and automation to scale as industry reforms drive climate adaptation and the evolving nature of work, blending venture capital and private equity approaches to identify inflection points in the industrial revolution and accelerate growth while fostering responsible innovation.

Upslope Ventures, founded in 2014 and based in Denver, Colorado, is an early-stage venture capital firm that invests in startups across the United States. Originally known as Galvanize Ventures, the firm focuses on a diverse range of sectors, including software as a service, hardware and internet of things, mobile, artificial intelligence, consumer products, e-commerce, content, fintech, aerospace, marketplaces, ad-tech, robotics, medical devices, virtual reality, and data science. Upslope Ventures emphasizes the importance of exceptional teams, believing that talent can emerge from any location. Beyond providing capital, the firm leverages its extensive network to empower entrepreneurs with valuable resources and support, enhancing their chances of success even in cases where direct investment is not made.

Founded in 2014, the Colorado Impact Fund is a Denver-based private equity firm dedicated to supporting local companies that generate consistent investment returns alongside positive community outcomes. The fund manages growth capital for entrepreneurs in sectors such as clean tech, natural foods, technology, healthcare, and education across the United States.

Insight Partners is a global software investor that partners with growth-stage technology and software companies. The firm focuses on growth-stage software, internet, and data services, with emphasis on fintech, cybersecurity, artificial intelligence and machine learning, DevOps, and healthcare. Based in New York City with offices in London, Tel Aviv, and Palo Alto, Insight Partners has backed more than 750 companies worldwide and has more than 55 portfolio companies that have achieved an IPO. As of 2022, the firm reports over $75 billion in assets under management. It seeks to fund and work closely with visionary executives, providing practical, hands-on software expertise to support growth from initial investment through to IPO.

Founded in 1999, Perceptive Advisors is a New York-based investment firm focused on the life sciences sector. It invests across various stages of company development, from seed to late-stage ventures and public equities, with a typical investment size ranging from $10 million to $200 million. The firm employs long/short equity strategies and conducts in-house research to identify promising opportunities in biotechnology, pharmaceuticals, life sciences, and healthcare services.

Caruso Ventures is a Boulder, Colorado-based venture capital firm founded in 2020 that invests in tech-enabled companies led by effective CEOs. It leverages scale-up experience to support the growth of the next generation of tech leaders. The firm is industry agnostic and focuses primarily on Colorado opportunities, where it may lead or participate as a follower. It structures investments through Special Purpose Vehicles to enable participation by other investors in select deals. Typical initial investments range from $500,000 to $1,000,000 at the early revenue ramp stage, with a likelihood of follow-on investments.

3Lines is a venture capital firm founded in 2016 and located in Greenwood Village, Colorado. The firm specializes in investing in early-stage companies within the Future of Work, Enterprise and Industry, and AI sectors. 3Lines typically provides funding ranging from $1 million to $5 million for companies in the United States and India that have annual revenues between $1 million and $10 million. The firm's focus is on supporting innovative businesses that are poised for growth in these dynamic and evolving markets.

Grotech Ventures is a Maryland-based venture capital firm founded in 1984 that focuses on early-stage and growth technology companies across the United States. The firm targets sectors including technology, cybersecurity, fintech, supply chain and logistics, software and vertical software, and TMT. It typically makes initial investments in the low to mid single digits per company and reserves capital for follow-on rounds to support growth through the company’s early and expansion stages. Grotech emphasizes a personal, long-term partnership with entrepreneurs, aligning its support with the founder’s definition of success. Beyond capital, it seeks to contribute through its experience, network, and hands-on involvement to help companies mature and scale.

Established in 1995, Rose Community Foundation is an independent non-profit organization based in Denver, Colorado. It aims to enhance the quality of life in the greater Denver community through strategic philanthropy focused on aging, child and family development, education, health, and Jewish life.

Congruent Ventures is a venture capital firm founded in 2017 and based in the San Francisco Bay Area. It specializes in early-stage investments in climate technology and sustainable development across North America, with a focus on mobility and urbanization, energy transition, food and agriculture, and sustainable production and consumption. The firm seeks technology companies that improve energy and resource efficiency and partners with teams capable of scaling hardware, software, or services. Its portfolio spans sectors such as transportation, consumer products, industrials, IT software, and related climate tech areas, reflecting a commitment to backing ventures that deliver measurable environmental impact.

GAN, established in 2010 and headquartered in Denver, Colorado, is a venture capital firm that serves as the investment arm of the Global Accelerator Network. It specializes in seed and early-stage investments, focusing on sectors such as aerospace, agriculture, analytics, robotics, SaaS, security, space-tech, mobile, transportation, machine learning, internet and information technology, and healthcare. GAN Ventures Fund I, managed by GAN Ventures, targets investing USD 0.1 million in approximately 50 to 60 companies, supporting the activities of accelerators within its network.

Meritage Funds is a Colorado-based private equity firm that focuses on growth and early-stage investments in technology-related companies with technology-enabled services and recurring revenue models. Founded in 1998 and based in the Denver area, the firm partners with entrepreneurs to scale businesses by providing capital and strategic guidance. It targets opportunities in information technology, communications, networking, and broader tech, aiming to support expansion and operational excellence. Meritage Funds emphasizes a collaborative approach, combining financial equity with hands-on guidance to help founders execute growth strategies, improve execution, and create long-term value.

Sapphire Ventures is a global software-focused venture capital firm with teams across Austin, London, Menlo Park and San Francisco. It partners with visionary management teams and venture funds to back companies that can become category leaders and has backed hundreds of companies worldwide, generating a track record of public listings and acquisitions. The firm operates a multi-pronged platform—Sapphire Ventures, Sapphire Partners and Sapphire Sport—that combines growth and early-stage investing with a portfolio-growth team providing strategic resources and operational support to help portfolio companies scale. Sapphire Sport is an early-stage investment vehicle focused on the intersection of sport, media and entertainment technology, while the broader platform targets software, cloud, cybersecurity, AI and other technology-enabled sectors.

Founded in 1989, OrbiMed is a New York-based healthcare-dedicated investment firm managing approximately $5 billion in assets. It invests across the spectrum of healthcare companies, from private start-ups to large multinational corporations, focusing on biopharmaceuticals, life sciences, digital health, medical devices, and diagnostics sectors globally.

Uranium Energy is a mining company specializing in uranium extraction through in-situ recovery (ISR) methods. It operates two extraction-ready ISR hubs in South Texas and Wyoming, with seven additional permitted ISR projects across the United States. The company also holds diversified uranium assets in Canada and Paraguay.

Established in 2019, this fund invests in healthcare companies that have partnerships with institutions on the University of Colorado Anschutz Medical Campus. It focuses on digital health, therapeutics, and devices, managing a $50 million portfolio.

Zoma Capital is an investment firm focused on market-based sustainable solutions that tackle environmental and social challenges. The firm targets various sectors, primarily concentrating on energy, water, and regional economic resiliency in locations such as Chile and Colorado. Its investment portfolio is diverse, encompassing multiple asset classes and sectors, all aimed at fostering sustainable development and addressing pressing global issues. By prioritizing innovative approaches, Zoma Capital seeks to contribute to a more resilient and sustainable future.

Founded in 2008 and based in Cottonwood Heights, Utah, Kickstart is a venture capital firm investing in early-stage companies across the Mountain West region. With a focus on technology-related sectors, particularly software, they have supported numerous successful startups such as Lucid, Podium, and Galileo over their 17-year history.

Alta Partners, established in 1996, is a venture capital firm headquartered in Jackson, Wyoming, with additional offices in Denver and Tiburon. The firm specializes in investing in the life sciences and healthcare sectors, focusing on companies that operate in life science, healthcare solutions, and service sectors. Alta Partners is known for its diverse and experienced team, which delivers tangible results for both the companies they invest in and their investors. The firm has evolved its investment strategy over time, currently focusing on stage-agnostic life sciences investments.

Blue Note Ventures is a venture capital firm based in Boulder, Colorado, investing in early-stage technology companies and supporting entrepreneurs in the information technology sector. It provides seed-scale capital, typically in the range of $0.1–$0.5 million per company, to help navigate early growth opportunities.

Founded in 2004 and based in Palo Alto, California, Uncork Capital is a venture capital firm focusing on seed-stage investments in SaaS, consumer goods, healthcare, and technology companies across the United States. The firm invests out of two funds: a $200M Seed fund and a $200M Opportunity fund for larger investments in mature portfolio companies.

The U.S. Department of Agriculture (USDA) leads initiatives in food, agriculture, natural resources, and rural development. It aims to expand markets for agricultural products globally, foster alternative markets domestically, improve rural infrastructure, enhance food safety, promote nutrition education, and manage public lands collaboratively.

Founders Fund is a San Francisco-based venture capital firm that backs science and technology companies across multiple stages, from seed to late-stage. It pursues transformative technologies and follows a founder-friendly investment approach that provides substantial support with minimal interference. The firm invests in ventures solving difficult problems across sectors such as aerospace and transportation, artificial intelligence, advanced computing, energy, healthcare, biotechnology, cybersecurity, fintech, consumer internet, software, robotics, and related technology fields. It has backed notable companies early, including SpaceX, Palantir, and Facebook, reflecting a history of partnering with ambitious founders to scale breakthrough technologies.

Founded in 2011, Privateer Holdings is a private equity firm specializing in investments within the legal cannabis sector. It aims to build global brands that lead and define this emerging industry.

Founded in 2012, Rubicon Technology Partners is a private equity firm headquartered in Boulder, Colorado. It focuses on investing in lower mid-market enterprise software companies with revenues between $25 million and $150 million, targeting control equity investments of $30-$75 million.

Founded in 2018, this Durango-based firm invests in early-stage startups headquartered across Colorado, focusing on regions outside the Front Range.

Arcadius Capital Partners, established in 2014, is a Calgary-based private equity firm with an additional office in Houston. The company specializes in mid-market investments, focusing on the upstream oil and gas sector in the United States and Canada.

Harbert Management is a privately owned investment management firm focused on alternative asset classes, with headquarters in Birmingham, Alabama, and offices across the United States and Europe. Established in 1993, it manages investments across private equity, venture capital, real estate, mezzanine debt, and related strategies. The firm targets value-enhancement real estate through its US Real Estate and European Real Estate platforms and serves a broad client base including foundations and endowments, funds of funds, pension funds, financial institutions, insurance companies, family offices, and high-net-worth individuals. It operates through dedicated investment teams in multiple cities to source and analyze opportunities, and its structure includes subsidiaries such as a venture capital affiliate. The firm emphasizes disciplined, principle-based investing and a global reach to access diverse markets and opportunities.