Waterline Ventures, founded in 2014 and based in Cambridge, Massachusetts, is a venture capital firm focused on early-stage investments in healthcare technology and services. The firm partners with innovative entrepreneurs who are addressing significant challenges in the healthcare industry, such as rising costs, inconsistent quality, and limited access to care. By supporting companies that aim to transform healthcare delivery, Waterline Ventures seeks to foster technological advancements that can enhance patient outcomes and overall healthcare efficiency. The firm recognizes the substantial and growing opportunity for innovation in this sector and is committed to backing entrepreneurs who are leading this change.
SimpliFed is a telehealth company founded in 2020 that offers virtual breastfeeding support to new and pregnant parents. The company focuses on providing accessible care during the peri and postnatal periods, addressing the challenges faced by parents, including sleep deprivation and concerns about infant nutrition. SimpliFed specializes in lactation and baby feeding support, as well as monitoring high-risk conditions such as hypertension and gestational diabetes. Through secure online and video-based connections, patients can engage with care navigators who guide them through their maternal care journey, helping them obtain quick answers to their questions about their infants' dietary needs.
Plenful
Series A in 2024
Plenful optimizes healthcare and pharmacy operations through intelligent workflow automation, data configuration and centralization, and machine learning. The company built a healthcare-focused AI automation platform to unburden staff, deliver meaningful financial and operational results, and drive more efficient patient care outcomes. Plenful is located in San Francisco, California and is backed by leading healthcare and software investors..
DoctorNow
Seed Round in 2024
DoctorNow builds system that is as simple to use as a word processor with complexity handled by their assistive artificial intelligence technology. Their single-minded obsession is to reduce time spent while maintaining data integrity and development to document the medical records as possible for informatics.
Ventricle Health
Seed Round in 2023
Ventricle Health offers evidence-based therapy, remote patient monitoring, patient education, and advocacy services for cardiac care.
Plenful
Seed Round in 2023
Plenful optimizes healthcare and pharmacy operations through intelligent workflow automation, data configuration and centralization, and machine learning. The company built a healthcare-focused AI automation platform to unburden staff, deliver meaningful financial and operational results, and drive more efficient patient care outcomes. Plenful is located in San Francisco, California and is backed by leading healthcare and software investors..
evolvedMD
Series A in 2023
evolvedMD focuses on integrating behavioral health services into primary care settings by embedding specialists directly within healthcare practices. This approach facilitates immediate collaborative care, allowing for a seamless patient experience. The company aims to provide comprehensive and ongoing support for patients, which enhances the overall quality of care and promotes better behavioral health outcomes. By adopting this innovative model, evolvedMD offers a practical solution for healthcare providers seeking to address the behavioral health needs of their patients effectively.
Andgo
Series A in 2022
Andgo Systems is a company that offers a shift fill automation tool to streamline scheduling practices in high-volume environments. Their software is designed to assist organizations in efficiently filling unplanned vacant shifts, addressing both immediate needs and planned absences. By providing automated and configurable workflows, Andgo simplifies complex scheduling processes and enhances communication regarding staffing needs. The company collaborates with organizations to tailor workflows that align with existing scheduling systems and processes, ensuring that the right personnel are assigned to the appropriate shifts. This approach ultimately aims to improve productivity and operational efficiency within organizations.
evolvedMD
Series A in 2022
evolvedMD focuses on integrating behavioral health services into primary care settings by embedding specialists directly within healthcare practices. This approach facilitates immediate collaborative care, allowing for a seamless patient experience. The company aims to provide comprehensive and ongoing support for patients, which enhances the overall quality of care and promotes better behavioral health outcomes. By adopting this innovative model, evolvedMD offers a practical solution for healthcare providers seeking to address the behavioral health needs of their patients effectively.
SimpliFed
Seed Round in 2022
SimpliFed is a telehealth company founded in 2020 that offers virtual breastfeeding support to new and pregnant parents. The company focuses on providing accessible care during the peri and postnatal periods, addressing the challenges faced by parents, including sleep deprivation and concerns about infant nutrition. SimpliFed specializes in lactation and baby feeding support, as well as monitoring high-risk conditions such as hypertension and gestational diabetes. Through secure online and video-based connections, patients can engage with care navigators who guide them through their maternal care journey, helping them obtain quick answers to their questions about their infants' dietary needs.
Nice Healthcare
Series A in 2022
Nice Healthcare LLC is a nurse practitioner-led primary care clinic based in Minneapolis, Minnesota, founded in 2017. The company provides comprehensive healthcare services primarily to small and medium-sized businesses, utilizing technology to facilitate both in-home and virtual care. Its offerings include virtual primary care, mental health therapy, and physical therapy. Patients can access these services through subscription-based plans, allowing them to schedule appointments for video visits or in-home consultations with licensed and certified nurse practitioners or physician assistants. This model aims to enhance accessibility and convenience in healthcare delivery.
Koneksa
Series C in 2022
Koneksa Health Inc. is a healthcare data analytics company focused on enhancing clinical studies and disease research through the use of remotely generated patient data. The company's software, Koneksa Compare, facilitates the collection, visualization, and analysis of patient-generated data, incorporating emerging technologies such as bio-sensors, activity trackers, and mobile-based questionnaires. This platform allows pharmaceutical and biotech companies, as well as academic researchers, to make informed decisions and regulatory claims based on objective data. Koneksa also provides biometric devices that generate electronic clinical outcome assessments and offers a dashboard for monitoring patient engagement, which includes reminders for study subjects. Founded in 2013 and headquartered in New York, Koneksa has an additional office in London, United Kingdom.
Cured
Series A in 2021
Cured, Inc. is a healthcare technology company that specializes in developing digital marketing tools and customer relationship management platforms for the healthcare sector. Founded in 2018 and headquartered in San Francisco, with additional offices in Chicago and Denver, Cured offers solutions that connect health systems and organizations to patients and their families. The company's cloud-based platform focuses on network management, patient marketing, and customer experience, providing design and product development services that address the unique challenges faced by healthcare and life sciences organizations. By leveraging modern business tools and integrating contact centers with electronic medical records, Cured enables clients to enhance brand awareness, improve patient satisfaction, and create engaging digital experiences that foster better healthcare behaviors and outcomes.
Carta Healthcare
Series A in 2021
Carta Healthcare, Inc. is a technology company that provides a software-as-a-service platform designed to improve patient care in hospitals. Founded in 2016 and headquartered in San Mateo, California, the platform leverages existing IT data to describe patient journeys and predict potential bottlenecks, such as recovery bed shortages and cancellations. By employing machine learning, Carta Healthcare enables hospitals to personalize care, allowing them to identify past patients with similar profiles and analyze their experiences. This approach enhances the efficiency and quality of healthcare data management by combining artificial intelligence with skilled human expertise, facilitating more effective and cost-efficient data abstraction for health systems.
Manifold
Seed Round in 2020
Manifold, Inc. is a technology company based in Oakland, California, with additional offices in San Francisco and Boston. Founded in 2016, it specializes in AI software programs and services tailored for the healthcare and financial sectors. The company has developed an AI-powered clinical research platform that aims to simplify the manual workflows associated with study and data management. By providing researchers with a centralized solution for collecting, harmonizing, and analyzing life sciences data, Manifold enables high-impact research and collaborations while reducing resource requirements. This innovative approach allows research organizations to conduct studies much faster and at lower costs, unlocking new insights in the process.
Koneksa
Series B in 2020
Koneksa Health Inc. is a healthcare data analytics company focused on enhancing clinical studies and disease research through the use of remotely generated patient data. The company's software, Koneksa Compare, facilitates the collection, visualization, and analysis of patient-generated data, incorporating emerging technologies such as bio-sensors, activity trackers, and mobile-based questionnaires. This platform allows pharmaceutical and biotech companies, as well as academic researchers, to make informed decisions and regulatory claims based on objective data. Koneksa also provides biometric devices that generate electronic clinical outcome assessments and offers a dashboard for monitoring patient engagement, which includes reminders for study subjects. Founded in 2013 and headquartered in New York, Koneksa has an additional office in London, United Kingdom.
Nice Healthcare
Seed Round in 2020
Nice Healthcare LLC is a nurse practitioner-led primary care clinic based in Minneapolis, Minnesota, founded in 2017. The company provides comprehensive healthcare services primarily to small and medium-sized businesses, utilizing technology to facilitate both in-home and virtual care. Its offerings include virtual primary care, mental health therapy, and physical therapy. Patients can access these services through subscription-based plans, allowing them to schedule appointments for video visits or in-home consultations with licensed and certified nurse practitioners or physician assistants. This model aims to enhance accessibility and convenience in healthcare delivery.
TimeDoc Health
Series A in 2020
TimeDoc Health is a Chicago-based healthcare IT and nursing services company that develops solutions to help physicians navigate the changing reimbursement landscape in healthcare.
RubiconMD
Series C in 2020
RubiconMD, Inc. operates an online platform that facilitates communication between primary care clinicians and specialists through its eConsult service. This platform allows primary care providers to seek expert guidance on medical cases, thereby enhancing patient care and reducing healthcare costs. In addition to the eConsult service, RubiconMD offers a continuing medical education (CME) program for eConsult submissions, live and on-demand webinars, and RubiconRx, a clinical pharmacy platform that supports patient medication access. The company also provides support in electronic health records, workflow integration, onboarding, and clinician engagement. Founded in 2013 and headquartered in New York, RubiconMD serves a diverse clientele, including employers, community health centers, correctional health facilities, health plans, and direct primary care practices.
Anagram
Series A in 2020
Anagram Inc. is a software company based in Santa Monica, California, that develops a platform to support healthcare professionals, particularly in the eye care sector, with the complexities of health insurance networks. Established in 2014 and previously known as Glass Health, Inc., Anagram offers an online insurance assistant designed to help manage patients' healthcare plans by highlighting out-of-network benefits and simplifying claim submissions. The platform enables eye care providers to navigate insurance benefits effectively, facilitating seamless billing and instant rebates through collaborations with eyewear labs and frame manufacturers. This approach allows providers to deliver services without the limitations imposed by managed vision plans, enhancing the overall patient experience.
Legacy
Seed Round in 2020
Legacy provides a service for at-home sperm testing and cryopreservation, allowing individuals to take control of their fertility health from the comfort of their homes. Their semen analysis is conducted in CLIA-certified labs, ensuring high-quality testing without the need for direct doctor involvement. As America's largest at-home fertility clinic for men, Legacy empowers clients to understand their reproductive health and plan for the future effectively.
Anagram
Funding Round in 2018
Anagram Inc. is a software company based in Santa Monica, California, that develops a platform to support healthcare professionals, particularly in the eye care sector, with the complexities of health insurance networks. Established in 2014 and previously known as Glass Health, Inc., Anagram offers an online insurance assistant designed to help manage patients' healthcare plans by highlighting out-of-network benefits and simplifying claim submissions. The platform enables eye care providers to navigate insurance benefits effectively, facilitating seamless billing and instant rebates through collaborations with eyewear labs and frame manufacturers. This approach allows providers to deliver services without the limitations imposed by managed vision plans, enhancing the overall patient experience.
Zipnosis
Series B in 2018
Zipnosis, Inc. is a healthcare company based in Minneapolis, Minnesota, that specializes in virtual care solutions. Founded in 2008, the company operates a platform that connects patients with clinicians through phone and video interviews, facilitating online diagnosis and triage. Zipnosis offers a unique service called ZipTicket, which acts as a healthcare boarding pass, allowing patients to access clinics for in-person assessments or lab tests when necessary. The platform is designed to enhance patient choice and convenience while improving efficiency for healthcare providers. Through its innovative approach, Zipnosis aims to expand access to immediate care and improve clinical outcomes for health organizations.
RubiconMD
Series B in 2018
RubiconMD, Inc. operates an online platform that facilitates communication between primary care clinicians and specialists through its eConsult service. This platform allows primary care providers to seek expert guidance on medical cases, thereby enhancing patient care and reducing healthcare costs. In addition to the eConsult service, RubiconMD offers a continuing medical education (CME) program for eConsult submissions, live and on-demand webinars, and RubiconRx, a clinical pharmacy platform that supports patient medication access. The company also provides support in electronic health records, workflow integration, onboarding, and clinician engagement. Founded in 2013 and headquartered in New York, RubiconMD serves a diverse clientele, including employers, community health centers, correctional health facilities, health plans, and direct primary care practices.
Common Sensing
Series A in 2018
Common Sensing develops and manufactures data-driven hardware and software medical device solutions for diabetes care that foster education and communication for patients while delivering decision support for clinicians. Common Sensing has a team of talented designers and engineers to develop Gocap™, a smart cap that turns existing injector pens into smart injectors.
Health iPASS
Series A in 2017
Health iPASS is redefining the patient revenue cycle by improving the patient experience from appointment to payment. Health iPASS helps providers promote price transparency, build trust, and increase their operating income by simplifying the check-in process and streamlining both time-of-service and residual balance patient payments through an innovative, multi-channel software solution. Our patient friendly system supports 850+ payers, 90+ practice management systems and is payment processor-agnostic. Many providers have realized 90-95% patient net collection rates, slashed denials by over 50%, and have significantly reduced cost and time to collect.
Carta Healthcare
Seed Round in 2017
Carta Healthcare, Inc. is a technology company that provides a software-as-a-service platform designed to improve patient care in hospitals. Founded in 2016 and headquartered in San Mateo, California, the platform leverages existing IT data to describe patient journeys and predict potential bottlenecks, such as recovery bed shortages and cancellations. By employing machine learning, Carta Healthcare enables hospitals to personalize care, allowing them to identify past patients with similar profiles and analyze their experiences. This approach enhances the efficiency and quality of healthcare data management by combining artificial intelligence with skilled human expertise, facilitating more effective and cost-efficient data abstraction for health systems.
Ambient Clinical Analytics
Series A in 2017
Ambient Clinical Analytics, Inc. develops healthcare data assimilation and decision support tools aimed at enhancing patient care in intensive care units, operating rooms, and emergency departments. The company's flagship product, AWARE, integrates with various electronic health record systems and bedside monitors to deliver crucial patient information on a single-screen dashboard, facilitating real-time clinical decision-making. Additionally, Ambient offers the Mayo Clinic YES Board, which enhances patient flow by providing real-time situational awareness. The company also specializes in syndromic surveillance solutions, including Sepsis DART, which aids in the detection and confirmation of sepsis, and the Ventilator-Induced Lung Injury Sniffer, designed for ventilator monitoring. Furthermore, Ambient provides the Synthesis Platform, which serves as an integration tool for AWARE and the Mayo Clinic solutions. Founded in 2013 and headquartered in Rochester, Minnesota, Ambient Clinical Analytics focuses on reducing healthcare costs and improving patient outcomes through its innovative tools and technology.
Madaket
Venture Round in 2017
Madaket, Inc. is a provider of SaaS solutions focused on the healthcare industry, headquartered in Cambridge, Massachusetts. Founded in 2012, the company specializes in automating healthcare enrollment processes, effectively connecting healthcare providers and payers to streamline administrative tasks. Madaket's platform enhances efficiency by reducing manual errors and allowing organizations to track the status of enrollments. The company has established exclusive partnerships with TriZetto Provider Solutions and HealthStream, facilitating access to a network that includes over 300,000 providers already in its system and an additional 325,000 providers under contract.
Hale Health
Venture Round in 2017
Hale Health Inc. operates a remote care platform designed to enhance communication between clinical teams and patients outside traditional office settings. Founded in 2013 and based in San Francisco, California, the platform allows patients to access their case histories, review treatment plans, and engage with health education materials. It facilitates seamless interactions through live video visits, secure messaging, and the sharing of photos, videos, and questionnaires. By enabling providers and patients to connect effectively, Hale Health aims to increase healthcare capacity, improve access, and enhance patient satisfaction while streamlining workflows for clinical practices.
RubiconMD
Series A in 2016
RubiconMD, Inc. operates an online platform that facilitates communication between primary care clinicians and specialists through its eConsult service. This platform allows primary care providers to seek expert guidance on medical cases, thereby enhancing patient care and reducing healthcare costs. In addition to the eConsult service, RubiconMD offers a continuing medical education (CME) program for eConsult submissions, live and on-demand webinars, and RubiconRx, a clinical pharmacy platform that supports patient medication access. The company also provides support in electronic health records, workflow integration, onboarding, and clinician engagement. Founded in 2013 and headquartered in New York, RubiconMD serves a diverse clientele, including employers, community health centers, correctional health facilities, health plans, and direct primary care practices.
NeueHealth
Series A in 2016
NeueHealth Inc is a healthcare company dedicated to providing high-quality, coordinated care to all health consumers, particularly those in aging and underserved populations. The company focuses on making healthcare accessible and affordable through strategic partnerships with providers and payors, aligning their interests to enhance the overall healthcare experience. By leveraging technology and data analytics, NeueHealth offers a suite of services that empower independent providers and medical groups to succeed in performance-based arrangements. This approach not only optimizes clinical outcomes but also aims to drive down costs and reduce systemic waste, ultimately delivering a more personalized and efficient healthcare experience for its members across various insurance markets, including the ACA Marketplace, Medicare, and Medicaid.
Zipnosis
Series A in 2016
Zipnosis, Inc. is a healthcare company based in Minneapolis, Minnesota, that specializes in virtual care solutions. Founded in 2008, the company operates a platform that connects patients with clinicians through phone and video interviews, facilitating online diagnosis and triage. Zipnosis offers a unique service called ZipTicket, which acts as a healthcare boarding pass, allowing patients to access clinics for in-person assessments or lab tests when necessary. The platform is designed to enhance patient choice and convenience while improving efficiency for healthcare providers. Through its innovative approach, Zipnosis aims to expand access to immediate care and improve clinical outcomes for health organizations.
Amwell
Venture Round in 2015
Amwell is a telehealth platform based in the United States that connects healthcare providers, insurers, patients, and innovators to enhance access to affordable and high-quality medical care. Founded in 2006 and headquartered in Boston, the company offers a comprehensive platform to address various telehealth needs, including urgent and acute care, post-acute care, chronic care management, and healthy living. With over a decade of experience, Amwell serves more than 240 health systems, comprising 2,000 hospitals and 55 health plan partners, and reaches over 150 million individuals, including 36,000 employers. The platform supports both on-demand and scheduled consultations, providing solutions for primary care, specialty consults, and chronic care programs like musculoskeletal and dermatology care.
1DocWay
Seed Round in 2015
1DocWay, Inc. is a telemedicine company that specializes in telepsychiatry, connecting psychiatric hospitals, clinics, emergency departments, and patients through a browser-based platform. Founded in 2011 and headquartered in New York, 1DocWay offers features such as videoconferencing, appointment scheduling, and medical records management, facilitating remote consultations with local psychiatrists and advanced practice registered nurses (APRNs). The company's services are tailored to meet the needs of rural, elderly, disabled, and busy patients, allowing them to conveniently schedule online appointments and receive care via secure video chat. This model not only enhances patient access to mental health services but also offers physicians increased scheduling flexibility and revenue opportunities. 1DocWay operates in multiple states across the U.S., including Arkansas, California, and Texas, and is a subsidiary of Genoa, a company focused on enhancing healthcare quality.
RubiconMD
Seed Round in 2014
RubiconMD, Inc. operates an online platform that facilitates communication between primary care clinicians and specialists through its eConsult service. This platform allows primary care providers to seek expert guidance on medical cases, thereby enhancing patient care and reducing healthcare costs. In addition to the eConsult service, RubiconMD offers a continuing medical education (CME) program for eConsult submissions, live and on-demand webinars, and RubiconRx, a clinical pharmacy platform that supports patient medication access. The company also provides support in electronic health records, workflow integration, onboarding, and clinician engagement. Founded in 2013 and headquartered in New York, RubiconMD serves a diverse clientele, including employers, community health centers, correctional health facilities, health plans, and direct primary care practices.
Wellframe
Series A in 2014
Wellframe Inc. is a Boston-based company that specializes in digital care management solutions aimed at enhancing the relationship between health plans and their members. Founded in 2011, Wellframe develops a mobile patient engagement platform that utilizes real-time member-generated data and artificial intelligence to create personalized care protocols. Its offerings include a member mobile application for daily health tracking, a care team dashboard for prioritizing patient needs, and two-way communication solutions. The company also provides various services such as implementation, operational change management, and analytics. Additionally, Wellframe's digital health advocate solutions encompass intake assessments, concierge programs, and integrated workflows to enhance care management. The company's strategic partnerships with health plans nationwide allow it to deliver impactful health management solutions that empower patients and improve care outcomes.
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