Spruce Capital Partners is a venture capital firm based in San Francisco, California, founded in 2013. It specializes in the life sciences sector, with a strong focus on biogreentech. The firm's principals are seasoned investors and thought leaders who possess extensive experience in guiding entrepreneurs towards building successful biogreentech companies. In addition to managing venture funds, Spruce Capital Partners is dedicated to fostering new talent in the industry, providing thought leadership, and promoting innovation on a global scale, particularly in regions such as Malaysia and the United States. The team has collaborated for over a decade, leveraging their collective expertise to influence the development of the life sciences industry.
A.Team is a professional network that facilitates the connection of top independent product builders, forming agile, full-stack teams tailored to help companies navigate digital disruptions. The platform is invite-only, ensuring a curated community of diverse tech talent with varied expertise. By enabling companies to adapt and develop technology in areas beyond their core competencies, A.Team supports organizations in pivoting their products and exploring new monetization strategies. This approach allows businesses to quickly assemble teams that can collaborate on significant projects, enhancing their ability to respond to changing market demands effectively.
GreenLight Biosciences
Post in 2022
GreenLight Biosciences, Inc. is a biotechnology company that specializes in developing RNA-based solutions for agricultural and pharmaceutical applications. Headquartered in Medford, Massachusetts, with an additional facility in North Carolina, the company focuses on producing high-quality RNA quickly and cost-effectively. GreenLight's technology platform facilitates the biological conversion of renewable substrates into valuable products, including chemicals and fuels. The company is actively involved in advancing vaccine development, particularly mRNA-based candidates aimed at preventing diseases such as SARS-CoV-2. Additionally, GreenLight engages in crop management and plant protection initiatives, contributing to sustainable agricultural practices and supporting the health of pollinators. Through its innovative approaches, GreenLight Biosciences aims to address global challenges in food security and public health.
Amfora
Series B in 2021
Amfora, Inc. is a biotechnology company based in San Francisco, California, established in 2016. The company focuses on developing nutritional forage crops through innovative biotechnological processes, particularly gene editing. Its mission is to address the increasing global demand for high-protein foods by enhancing the nutritional density of crops such as soybeans, wheat, and rice. By improving the protein content of these food and feed crops, Amfora aims to contribute to a more sustainable food system, reducing both costs and the environmental impact associated with food production.
Provivi
Series C in 2020
Provivi Inc. specializes in developing biopesticides aimed at pest management in agriculture, commercial sectors, households, and public health. The company's innovative approach focuses on using insect pheromones, which provide a safe, environmentally friendly alternative to traditional pesticides. By leveraging biocatalysis technology initially developed at the California Institute of Technology, Provivi enhances the synthesis of these biopesticides, ensuring they are effective and free from toxic residues. Founded in 2013 and based in Santa Monica, California, the company collaborates with distributors worldwide to deliver its products, which are designed to protect food supplies sustainably and affordably. With a team of experienced professionals from biotechnology and the agricultural chemicals industry, Provivi is positioned to transform pest management practices through its advanced biological processes.
GreenLight Biosciences
Series D in 2020
GreenLight Biosciences, Inc. is a biotechnology company that specializes in developing RNA-based solutions for agricultural and pharmaceutical applications. Headquartered in Medford, Massachusetts, with an additional facility in North Carolina, the company focuses on producing high-quality RNA quickly and cost-effectively. GreenLight's technology platform facilitates the biological conversion of renewable substrates into valuable products, including chemicals and fuels. The company is actively involved in advancing vaccine development, particularly mRNA-based candidates aimed at preventing diseases such as SARS-CoV-2. Additionally, GreenLight engages in crop management and plant protection initiatives, contributing to sustainable agricultural practices and supporting the health of pollinators. Through its innovative approaches, GreenLight Biosciences aims to address global challenges in food security and public health.
Pivot Bio
Series C in 2020
Pivot Bio is improving and using a deep understanding of the microbiome to advance crop nutrition. They believe that microbes can deliver nutrients, protect against pests, and improve crop quality better than chemical fertilizers and pesticides. They leverage engineering principles and data science to map the dynamics of the plant microbiome and evolve beneficial traits. Their team thrives on collaboration and communication as they seek to create revolutionary fertilizers that transform food supply and improves the planet. Pivot Bio's proprietary ON Technology harnesses the power of naturally occurring microbes to provide more nutrients to crops. It’s a smart, sustainable way for farmers to improve yield as they work to help feed the world’s growing population. Their current efforts are focused on enabling microbes to fix and supply more nitrogen to corn. Pivot Bio was founded in 2010 and is headquartered in Berkeley, California, United States.
Crop Enhancement
Series B in 2020
Crop Enhancement LLC is an innovative specialty materials company based in San Jose, California, founded in 2011. The company focuses on developing advanced formulation technologies for agricultural chemicals, which facilitate the controlled release of pesticides, herbicides, and fertilizers into targeted microenvironments. By employing environmentally friendly chemistry, Crop Enhancement aims to enhance crop yields and profitability while promoting sustainable farming practices. Its proprietary products include films that modify plant surfaces, improving resistance to pests and diseases. This technology not only reduces the reliance on synthetic pesticides but also ensures precise and effective delivery of active ingredients, contributing to a more sustainable approach to agriculture.
Provivi
Series C in 2019
Provivi Inc. specializes in developing biopesticides aimed at pest management in agriculture, commercial sectors, households, and public health. The company's innovative approach focuses on using insect pheromones, which provide a safe, environmentally friendly alternative to traditional pesticides. By leveraging biocatalysis technology initially developed at the California Institute of Technology, Provivi enhances the synthesis of these biopesticides, ensuring they are effective and free from toxic residues. Founded in 2013 and based in Santa Monica, California, the company collaborates with distributors worldwide to deliver its products, which are designed to protect food supplies sustainably and affordably. With a team of experienced professionals from biotechnology and the agricultural chemicals industry, Provivi is positioned to transform pest management practices through its advanced biological processes.
Consumer Physics
Venture Round in 2018
Consumer Physics Inc. is a technology company based in Tel Aviv, Israel, that specializes in the development and distribution of molecular sensors marketed under the SCiO brand. Founded in 2011, the company offers the SCiO, a compact near-infrared spectrometer designed for real-time material analysis. This device connects to smartphone applications and a cloud-based database of material fingerprints, empowering both consumers and businesses to analyze the composition of various materials anytime and anywhere. Consumer Physics also provides a platform for businesses and third-party developers to create custom molecular sensing models and mobile applications. By leveraging the SCiO technology, clients in industries such as food and agriculture can make informed decisions, potentially reducing food waste and enhancing operational efficiency. The company has established strategic partnerships to further its mission and support its innovative offerings.
Inscripta
Series C in 2018
Inscripta, Inc. is a gene editing technology company based in Boulder, Colorado, with additional offices in Pleasanton and San Diego, California. Founded in 2015, the company is focused on developing advanced CRISPR enzymes, specifically its proprietary MADzymes, to facilitate precision gene editing. Inscripta has created the first benchtop platform for scalable digital genome engineering, which includes an instrument, consumables, software, and assays that enable fully automated workflows for massively parallel editing of single cells. This innovative platform aims to empower scientists by overcoming existing technical and licensing challenges in gene editing research. By providing tools that allow for the generation of extensive libraries of designer proteins and genome variants, Inscripta supports researchers in designing, engineering, and evaluating genetic modifications with unprecedented ease and efficiency.
Provivi
Series B in 2017
Provivi Inc. specializes in developing biopesticides aimed at pest management in agriculture, commercial sectors, households, and public health. The company's innovative approach focuses on using insect pheromones, which provide a safe, environmentally friendly alternative to traditional pesticides. By leveraging biocatalysis technology initially developed at the California Institute of Technology, Provivi enhances the synthesis of these biopesticides, ensuring they are effective and free from toxic residues. Founded in 2013 and based in Santa Monica, California, the company collaborates with distributors worldwide to deliver its products, which are designed to protect food supplies sustainably and affordably. With a team of experienced professionals from biotechnology and the agricultural chemicals industry, Provivi is positioned to transform pest management practices through its advanced biological processes.
Consumer Physics
Series C in 2017
Consumer Physics Inc. is a technology company based in Tel Aviv, Israel, that specializes in the development and distribution of molecular sensors marketed under the SCiO brand. Founded in 2011, the company offers the SCiO, a compact near-infrared spectrometer designed for real-time material analysis. This device connects to smartphone applications and a cloud-based database of material fingerprints, empowering both consumers and businesses to analyze the composition of various materials anytime and anywhere. Consumer Physics also provides a platform for businesses and third-party developers to create custom molecular sensing models and mobile applications. By leveraging the SCiO technology, clients in industries such as food and agriculture can make informed decisions, potentially reducing food waste and enhancing operational efficiency. The company has established strategic partnerships to further its mission and support its innovative offerings.
Evolve Biosystems
Series B in 2017
Evolve Biosystems, Inc. is a biotechnology company based in Davis, California, focused on developing and marketing probiotic-based biotherapeutics aimed at establishing, restoring, and maintaining a healthy human microbiome. The company specializes in addressing gut dysbiosis across the human life cycle, particularly in newborns during their first six months of life. Evolve Biosystems utilizes a platform that combines specific probiotic bacteria with prebiotic oligosaccharides to create effective delivery systems. Their products include consumer-directed solutions for home use as well as specialized formulations for neonatal intensive care units. In addition to human health, the company also applies its discovery platform to address similar microbiome issues in production animals. Evolve Biosystems was incorporated in 2011.
Amfora
Series A in 2017
Amfora, Inc. is a biotechnology company based in San Francisco, California, established in 2016. The company focuses on developing nutritional forage crops through innovative biotechnological processes, particularly gene editing. Its mission is to address the increasing global demand for high-protein foods by enhancing the nutritional density of crops such as soybeans, wheat, and rice. By improving the protein content of these food and feed crops, Amfora aims to contribute to a more sustainable food system, reducing both costs and the environmental impact associated with food production.
Agerpoint
Series B in 2016
Agerpoint, Inc. specializes in providing information management solutions tailored for growers of tree and vine crops, as well as insurers and investors. The company develops advanced technologies to digitize and analyze natural environments, utilizing artificial intelligence and high-performance computing. Through its GroveTracker platform, Agerpoint offers growers critical insights into their crop holdings, including statistical and photographic data on their orchards and vineyards. The company integrates data from various sources, such as drones and satellites, to create precise digital records that enhance decision-making across sectors like agriculture, forestry, and environmental conservation. Founded in 2012 and headquartered in Research Triangle Park, North Carolina, Agerpoint aims to improve the understanding of plants and forests while contributing to efforts against climate change.
Gevo
Series D in 2010
Gevo, Inc. is a renewable fuels company based in Englewood, Colorado, specializing in the development and commercialization of sustainable alternatives to petroleum-based products. Founded in 2005, Gevo focuses on producing biofuels such as gasoline, jet fuel, diesel fuel, and isobutanol derived from low-carbon renewable carbohydrates. The company aims to achieve zero carbon emissions and reduce greenhouse gas emissions through its innovative processes, which also include the development of renewable electricity and natural gas. In addition to biofuels, Gevo's product offerings encompass renewable biodiesel, isooctane, isobutylene, ethanol, and animal feed. The company operates through various segments, including Renewable Natural Gas and Agri-Energy, where it conducts research and development for sustainable aviation fuel and other renewable hydrocarbon products, as well as capturing methane gas from dairy cow manure.
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