ShangBay Capital

Fluid Biomed is a medical device start-up dedicated to the development of an innovative implantable dissolving stent specifically designed for the treatment of brain aneurysms. Founded by a team of neurosurgeons, the company aims to enhance patient outcomes by offering a bio-absorbable polymer-based flow-diverting stent that promotes healing and minimizes the need for invasive surgical procedures. This revolutionary device gently redirects blood flow to facilitate the healing of weakened aneurysms, enabling physicians to treat patients efficiently and effectively while reducing the risk of complications such as stroke.

Inquis Medical is focused on developing innovative thrombectomy technology aimed at enhancing the management of venous thromboembolic diseases. The company's medical devices are designed to address unmet clinical needs while improving the standard of care in this area. Inquis Medical's key offering is an efficient single-pass thrombectomy system that minimizes blood loss, contributing to better patient outcomes. Through its advanced technology, Inquis Medical seeks to provide solutions that have a lasting impact on the treatment of thromboembolic conditions.

Venova Medical specializes in developing vascular access systems aimed at improving the experience of patients requiring renal replacement therapy, particularly those needing hemodialysis. Founded in 2018 and based in Los Gatos, California, the company focuses on overcoming challenges related to vascular access creation. By addressing both patient-level and systemic barriers, Venova Medical provides solutions that facilitate quicker functioning access with reduced need for intervention. This approach not only enhances vascular access outcomes but also aims to lower associated costs, ultimately simplifying the process for patients in need of hemodialysis.

Laplace Interventional is a medical device company focused on developing transcatheter tricuspid valve technology aimed at treating tricuspid regurgitation. The company's innovative prosthetic valve is delivered through a minimally invasive procedure, eliminating the need for open-heart surgery. This approach not only enhances patients' life expectancy but also significantly improves their quality of life by reducing the risk of future complications. Through its advancements in cardiac care, Laplace Interventional is dedicated to providing effective solutions for patients worldwide.

Luminopia is focused on developing innovative treatments for significant neuro-visual disorders, particularly amblyopia, commonly known as lazy eye, which is a leading cause of vision loss in children. The company is creating digital therapeutics that undergo rigorous evaluation for FDA approval while ensuring they are engaging for patients. In collaboration with Boston Children's Hospital, Luminopia is advancing its primary product, Luminopia One, which utilizes a binocular therapeutic approach to effectively address amblyopia. This development aims to enhance the capabilities of healthcare professionals in treating these critical vision disorders.

Solenic Medical, a medical device company that develops a non-invasive treatment for infected metallic implants in the body. The company leverages the properties of alternating magnetic fields (AMF) generated from external coils to eradicate biofilm on the surface of medical implants. This non-invasive treatment addresses a major complication of various surgeries, such as knee and hip replacements, as well as in trauma-related implants such as plates and rods. Its AMF technology has the potential to completely replace the very expensive and risky two-step revision surgical procedure, which is the current standard of care for chronic infections on medical implants. Rajiv Chopra and David Greenberg founded it in College Station, Texas in 2019.

Alleviant Medical focuses on developing a minimally-invasive medical device to treat congestive heart failure. Its proprietary transcatheter technology is designed to create a paradigm shift in the treatment of heart failure by relieving patient symptoms, improving quality of life, and reducing hospital readmissions for over 6 million Americans currently suffering from this disease.

SetPoint Medical is a clinical-stage bioelectronic medicine company based in Valencia, California, focused on developing implantable neuromodulation devices aimed at treating chronic autoimmune diseases. The company is creating a platform that stimulates the vagus nerve to activate the body's natural inflammatory reflex, leading to a systemic immune-restorative effect. This innovative approach offers an alternative treatment option for conditions such as rheumatoid arthritis and inflammatory bowel disease, with the potential for reduced risks and costs compared to traditional drug therapies. SetPoint Medical, originally known as Innovative Metabolics Inc. until its name change in 2008, aims to provide patients and healthcare providers with effective solutions for managing debilitating inflammatory diseases.

Telesair is a medical device company focused on developing innovative respiratory care solutions aimed at enhancing the quality of life for individuals with lung diseases. By leveraging real clinical data, engineering design, software, and Internet of Things (IoT) technology, Telesair creates respiratory care equipment that is both safer and more efficient. Their products are designed for use in clinical settings and at home, facilitating a transition for patients from hospital care to home care more swiftly. This approach not only improves patient outcomes but also optimizes the standard of care in respiratory health management.

Luminopia is focused on developing innovative treatments for significant neuro-visual disorders, particularly amblyopia, commonly known as lazy eye, which is a leading cause of vision loss in children. The company is creating digital therapeutics that undergo rigorous evaluation for FDA approval while ensuring they are engaging for patients. In collaboration with Boston Children's Hospital, Luminopia is advancing its primary product, Luminopia One, which utilizes a binocular therapeutic approach to effectively address amblyopia. This development aims to enhance the capabilities of healthcare professionals in treating these critical vision disorders.

Fluid Biomed is a medical device start-up dedicated to the development of an innovative implantable dissolving stent specifically designed for the treatment of brain aneurysms. Founded by a team of neurosurgeons, the company aims to enhance patient outcomes by offering a bio-absorbable polymer-based flow-diverting stent that promotes healing and minimizes the need for invasive surgical procedures. This revolutionary device gently redirects blood flow to facilitate the healing of weakened aneurysms, enabling physicians to treat patients efficiently and effectively while reducing the risk of complications such as stroke.

Neuro42 is focused on developing and commercializing advanced magnetic resonance imaging (MRI) and robotics technology aimed at diagnosing and guiding interventions for neurological conditions. The company has created portable MRI machines designed to enhance the diagnostic process for various brain issues, including traumatic injuries, epilepsy, and tumors. By providing imaging solutions that facilitate triaging, screening, and direct robotic interventions, Neuro42 aims to improve patient care, particularly for those who have suffered strokes. This innovative approach shifts the point of care from traditional MRI suites to more accessible settings, enabling timely and effective treatment for neurological conditions.

Emboline is a medical device company with a game-changing device for total embolic protection during percutaneous heart valve repair and replacement procedures and other cardiovascular procedures with embolic risks.

SetPoint Medical is a clinical-stage bioelectronic medicine company based in Valencia, California, focused on developing implantable neuromodulation devices aimed at treating chronic autoimmune diseases. The company is creating a platform that stimulates the vagus nerve to activate the body's natural inflammatory reflex, leading to a systemic immune-restorative effect. This innovative approach offers an alternative treatment option for conditions such as rheumatoid arthritis and inflammatory bowel disease, with the potential for reduced risks and costs compared to traditional drug therapies. SetPoint Medical, originally known as Innovative Metabolics Inc. until its name change in 2008, aims to provide patients and healthcare providers with effective solutions for managing debilitating inflammatory diseases.

Aqua Medical, Inc. is focused on developing innovative, vapor-based, endoscopic ablation technology aimed at treating gastrointestinal diseases and preventing gastrointestinal cancers. Founded in 2016 and based in Santa Ana, California, the company utilizes high-temperature water vapor generated by a radiofrequency generator. This vapor is delivered endoscopically through proprietary catheters, allowing for a minimally invasive approach to treat various conditions within the gastrointestinal tract, including pancreatic cysts and esophageal issues. Aqua Medical's platform technology offers a convenient and effective alternative to traditional surgical methods, enhancing treatment options for medical practitioners and their patients.

Zap Surgical Systems, Inc. is a medical technology company based in San Carlos, California, founded in 2014. The company designs and manufactures the ZAP-X radiosurgery platform, which is utilized for treating brain tumors and various conditions affecting the head and neck. This innovative system features a self-shielded design that eliminates the necessity for traditional radiation vaults, allowing for greater accessibility and point-of-care delivery in settings such as physician offices, ambulatory surgery centers, and satellite facilities. By enabling neurosurgeons and radiation oncologists to utilize precision radiation more effectively, Zap Surgical Systems aims to enhance treatment options for patients requiring advanced surgical interventions.

Meditrina, Inc. is a medical device company based in San Jose, California, specializing in tissue removal solutions for intrauterine pathology. Founded in 2016, the company has developed the Aveta System, an all-in-one solution designed for hysteroscopic diagnostic and therapeutic procedures. This system enables healthcare professionals to perform tasks such as the removal of polyps and fibroids in both office and operating room settings. The Aveta System features wide-angle HD hysteroscopy with electronic image-lock, advanced fluid management for better pressure and fluid control, and a compact design that allows for seamless integration into various medical environments. By providing advanced, convenient, and cost-effective options, Meditrina aims to enhance the care experience for both patients and physicians.

Lucira Health, Inc. is a medical technology company based in Emeryville, California, that specializes in the development and commercialization of innovative infectious disease test kits. Founded in 2013, the company focuses on creating accessible and user-friendly testing solutions, including a disposable COVID-19 test kit designed for home use. This kit provides centralized-laboratory-accurate molecular testing in a compact format that operates on two AA batteries. It connects consumers to treatment options through a mobile application and offers a dual testing capability to determine whether viral respiratory symptoms are caused by COVID-19 or influenza. Lucira Health aims to enhance the accessibility and efficiency of infectious disease diagnostics.

Corinth MedTech, Inc. is a medical device company based in Cupertino, California, specializing in the manufacture of disposable bipolar transurethral and transcervical resectoscopes. Founded in 2011, the company has developed systems for endoscopically controlled tissue removal for male patients with benign prostatic hyperplasia (BPH) and for female patients with conditions such as abnormal uterine bleeding, fibroids, and polyps requiring hysteroscopic intervention. Corinth MedTech's proprietary technology enables medical professionals to perform precise resection and coagulation of prostate adenomas and bladder tumors, facilitating effective treatment under continuous flow conditions. The company aims to enhance patient outcomes through its innovative medical solutions.

Apostle, Inc. is a biotechnology company based in Menlo Park, California, focused on developing AI-enabled nanoDiagnostics technology for early cancer detection. Founded in 2017, the company specializes in liquid biopsy techniques, utilizing circulating free DNA (cfDNA) as a biomarker for analysis. Its innovative products include the Apostle MiniMax, a system for efficiently capturing cfDNA from blood samples, the Apostle MagTouch, which automates nucleic acid isolation, and the Apostle MiniEnrich, a technology for high-resolution DNA size enrichment. In response to the COVID-19 pandemic, Apostle introduced the Apostle COVID-19 Viral RNA Isolation System, contributing to public health efforts and serving over 13 million individuals. Apostle Diagnostics, a clinical laboratory branch of the company, is CLIA certified and California State licensed, providing accurate clinical testing services and having served over 30,000 people. Through its advancements in bioinformatics and nanotechnology, Apostle aims to enhance the diagnosis and treatment of various diseases, particularly cancer.

Lucira Health, Inc. is a medical technology company based in Emeryville, California, that specializes in the development and commercialization of innovative infectious disease test kits. Founded in 2013, the company focuses on creating accessible and user-friendly testing solutions, including a disposable COVID-19 test kit designed for home use. This kit provides centralized-laboratory-accurate molecular testing in a compact format that operates on two AA batteries. It connects consumers to treatment options through a mobile application and offers a dual testing capability to determine whether viral respiratory symptoms are caused by COVID-19 or influenza. Lucira Health aims to enhance the accessibility and efficiency of infectious disease diagnostics.

NeuroVasc Technologies, Inc. is a medical device company focused on developing catheter-based technologies for treating neurovascular diseases, particularly in the context of stroke management. Established in 2015 and headquartered in Laguna Hills, California, the company has developed the Versi system, a mechanical thrombectomy device designed to remove blood clots that cause strokes. This innovative system features a flow protector and a retriever that can be delivered through a microcatheter, allowing for the regulation of blood flow during the clot retrieval process without the need for a balloon guide catheter. NeuroVasc Technologies aims to enhance treatment options for patients suffering from acute ischemic strokes by providing tools that facilitate effective intervention for healthcare professionals.

Emboline is a medical device company with a game-changing device for total embolic protection during percutaneous heart valve repair and replacement procedures and other cardiovascular procedures with embolic risks.