Garuda Therapeutics
Series A in 2025
Garuda Therapeutics develops off-the-shelf hematopoietic stem cell therapies to treat life-threatening diseases. It seeks to eliminate dependency on donor or patient cells for blood stem cell transplants, leveraging a platform technology that generates off-the-shelf, self-renewing blood stem cells that are HLA-compatible and transgene-free, providing patients with rapid and broad access to durable therapies.
VieCure
Venture Round in 2024
VieCure develops an AI-driven platform that transforms cancer care by providing personalized, evidence-based treatment plans. It curates global cancer knowledge and tailors it to each patient's unique needs, ensuring compliance with national standards and genomic guidelines.
Slingshot Biosciences
Series A in 2024
Slingshot Biosciences develops engineered synthetic cells to accelerate drug research and enable diagnostics and therapeutics. The company creates next-generation cellular tools that aim to simplify complex experiments, improve data standardization in cell analysis, and provide cost-effective solutions for research programs. Its work includes aligning cellular properties such as forward and side scatter of white blood cells to enable more consistent measurements and faster interpretation. By removing cold-chain barriers, Slingshot Biosciences seeks to broaden access to advanced diagnostics and therapeutics, supporting programs focused on neglected and rare diseases. Operating in the industrial synthetic biology space, the company concentrates on practical cellular technologies that can shorten development timelines and reduce costs for researchers.
SeLux Diagnostics
Venture Round in 2024
SeLux Diagnostics, Inc. is a biotechnology company based in Charlestown, Massachusetts, focused on developing a next-generation phenotyping platform for antibiotic susceptibility testing and diagnostics of infectious diseases. Established in 2014, the company utilizes synthetic amplifier technology to enhance the speed and complexity of antibiotic susceptibility testing, thereby significantly improving patient care. By facilitating the rapid selection of personalized antimicrobial therapies, SeLux aims to transform the management of infectious diseases, ultimately saving lives, reducing hospital stays, and combating the growing issue of antibiotic resistance through more targeted treatments.
Elephas is a company focused on revolutionizing cancer treatment through its innovative live tumor imaging diagnostics platform. By leveraging advances in cancer biology, multimodal microscopy, engineering, and artificial intelligence, Elephas aims to enhance clinical decision-making and personalize therapy for cancer patients. The company's approach involves the use of human live tumor fragments, allowing clinicians to determine the most effective treatment strategies for individual patients. In doing so, Elephas not only seeks to improve patient outcomes but also to expedite the drug development process, addressing the significant challenges faced in oncology.
Aro Biotherapeutics
Series B in 2023
Aro Biotherapeutics is a biotechnology company based in Philadelphia, Pennsylvania, focused on developing a novel protein drug platform known as Centyrins. These small, non-antibody protein scaffolds are designed to enhance treatment efficacy and safety for patients with cancer and other serious diseases. Aro Biotherapeutics has established a wholly-owned pipeline of Centyrins targeted at oncology and immunology applications. The unique structure of Centyrins allows for multi-specificity and the targeted delivery of complex drug payloads, including nucleic acids, which may aid in advancing therapeutic mechanisms and unlocking the potential of genetic medicines. Established in 2017, the company aims to innovate treatments that improve patient outcomes in challenging medical conditions.
Octave is a clinical platform developer focused on transforming the care landscape for multiple sclerosis and other neurodegenerative diseases. The company creates a platform that generates, analyzes, and integrates data to improve patient outcomes and reduce overall healthcare costs. By optimizing medication usage and healthcare services, Octave aims to enhance the efficiency of the pharmaceutical industry throughout the entire lifecycle of drug development, which includes discovery, clinical trials, and post-marketing phases. Their approach utilizes real-world evidence to inform decision-making, ultimately striving to set a new standard in multiple sclerosis care.
SpeeDx
Venture Round in 2023
SpeeDx is a company that specializes in molecular diagnostic solutions, offering advanced testing systems that provide comprehensive information for enhanced patient management. Utilizing innovative real-time polymerase chain reaction (qPCR) technology, SpeeDx develops market-leading multiplex detection and priming strategies. Its product portfolio includes diagnostics for sexually transmitted infections (STIs), antibiotic resistance markers, and respiratory diseases. By focusing on multiplex systems, SpeeDx enables healthcare providers to efficiently test for various infectious diseases and assess antibiotic resistance, thereby improving clinical decision-making and patient outcomes.
Faro Health
Series A in 2023
Faro Health develops a cloud-based medical platform that standardizes, automates, and streamlines clinical trial processes. Its system handles administrative burdens, allowing clinical researchers to focus on critical decisions that drive clinical value.
Garuda Therapeutics
Series B in 2023
Garuda Therapeutics develops off-the-shelf hematopoietic stem cell therapies to treat life-threatening diseases. It seeks to eliminate dependency on donor or patient cells for blood stem cell transplants, leveraging a platform technology that generates off-the-shelf, self-renewing blood stem cells that are HLA-compatible and transgene-free, providing patients with rapid and broad access to durable therapies.
Slingshot Biosciences
Series A in 2023
Slingshot Biosciences develops engineered synthetic cells to accelerate drug research and enable diagnostics and therapeutics. The company creates next-generation cellular tools that aim to simplify complex experiments, improve data standardization in cell analysis, and provide cost-effective solutions for research programs. Its work includes aligning cellular properties such as forward and side scatter of white blood cells to enable more consistent measurements and faster interpretation. By removing cold-chain barriers, Slingshot Biosciences seeks to broaden access to advanced diagnostics and therapeutics, supporting programs focused on neglected and rare diseases. Operating in the industrial synthetic biology space, the company concentrates on practical cellular technologies that can shorten development timelines and reduce costs for researchers.
Perceiv AI
Seed Round in 2022
Perceiv AI specializes in precision medicine using advanced machine learning algorithms. It helps pharmaceutical companies enhance clinical trial success by identifying suitable patient subpopulations for complex diseases, such as Alzheimer's and cardiovascular conditions.
Opna Bio is a clinical-stage biopharmaceutical company dedicated to the discovery and development of innovative oncology therapeutics. The company focuses on creating new drugs that target the hallmarks of cancer, particularly addressing immune suppression mechanisms that contribute to cancer cell growth. By developing therapies that aim to disrupt these processes, Opna Bio seeks to provide physicians with more effective treatment options for cancer patients, thereby advancing the standard of care in oncology.
Elephas is a company focused on revolutionizing cancer treatment through its innovative live tumor imaging diagnostics platform. By leveraging advances in cancer biology, multimodal microscopy, engineering, and artificial intelligence, Elephas aims to enhance clinical decision-making and personalize therapy for cancer patients. The company's approach involves the use of human live tumor fragments, allowing clinicians to determine the most effective treatment strategies for individual patients. In doing so, Elephas not only seeks to improve patient outcomes but also to expedite the drug development process, addressing the significant challenges faced in oncology.
Syapse
Venture Round in 2022
Syapse, Inc. is a technology company that specializes in precision medicine through its innovative software platform, which aggregates and analyzes clinical, molecular, treatment, and outcomes data. Founded in 2008 and headquartered in San Francisco, California, with an additional office in Radnor, Pennsylvania, Syapse aims to enhance healthcare by providing actionable insights that support data-driven decision-making in precision oncology. The company operates the Syapse Learning Health Network, a global network that enables health systems and life sciences collaborators to share real-world cancer data. This network empowers healthcare organizations to collaborate effectively, ensuring that oncologists and decision-makers have access to comprehensive patient insights at the point of care, ultimately driving improved outcomes for cancer patients. Syapse has established strategic partnerships, including a collaboration with Pfizer, to further its mission of delivering personalized care based on robust real-world evidence.
CAMP4 Therapeutics
Series B in 2022
CAMP4 Therapeutics Corporation is a bioinformatics company founded in 2015 and based in Cambridge, Massachusetts. The company specializes in gene regulation circuitry, focusing on the fundamental causes of diseases by manipulating gene expression. Utilizing its proprietary 4-D gene circuitry platform, CAMP4 codifies the activation of approximately 24,000 human genes into a discrete set of combinatorial rules based on existing cellular signaling pathways. This innovative approach allows CAMP4 to effectively control gene production, thereby accelerating the development of new therapies. By employing this technology, the company aims to streamline the drug development process, significantly reducing both the time and risks associated with bringing new medicines to patients.
Triumvira Immunologics
Series A in 2022
Triumvira Immunologics USA, Inc. is an immunotherapy company founded in 2015 and headquartered in Austin, Texas, with research facilities in Hamilton, Canada. The company focuses on developing innovative T cell therapies aimed at improving cancer treatment outcomes. Its primary offerings include chimeric antigen receptor (CAR) therapies and engineered T cell receptor (TCR) therapies. A key aspect of Triumvira's approach is its proprietary T cell Antigen Coupler (TAC) technology, which recruits the entire natural T cell receptor and operates independently of the major histocompatibility complex (MHC). This technology enables the development of more effective therapies for a wider array of patients suffering from both solid and liquid malignancies, as well as other diseases beyond cancer.
DNAnexus, Inc. is a cloud-based provider of genome informatics and data management tools, primarily serving enterprises and organizations involved in genomic medicine. Founded in 2009 and headquartered in Mountain View, California, the company offers a platform that facilitates the analysis of raw sequencing data and the integration of genomic data with clinical information. Its suite of products includes MOSAIC Microbiome for collaborative research on the human microbiome, DNAnexus Apollo for clinico-genomic data exploration, and DNAnexus Titan for data analysis. Additionally, the DNAnexus Portals provide secure online workspaces for cross-disciplinary collaboration, while the Clinico-Genomic Data Solution addresses the need for disease-specific datasets through partnerships with healthcare providers. The company has established itself as a key player in the biopharmaceutical, diagnostic, and academic research sectors, enabling clients to tackle complex challenges in human health with enhanced security and scalability. DNAnexus also maintains a strategic alliance with WuXi NextCODE Genomics and has locations in San Francisco, London, and Prague.
SeLux Diagnostics
Series C in 2022
SeLux Diagnostics, Inc. is a biotechnology company based in Charlestown, Massachusetts, focused on developing a next-generation phenotyping platform for antibiotic susceptibility testing and diagnostics of infectious diseases. Established in 2014, the company utilizes synthetic amplifier technology to enhance the speed and complexity of antibiotic susceptibility testing, thereby significantly improving patient care. By facilitating the rapid selection of personalized antimicrobial therapies, SeLux aims to transform the management of infectious diseases, ultimately saving lives, reducing hospital stays, and combating the growing issue of antibiotic resistance through more targeted treatments.
Story Health
Series A in 2022
Story Health Corporation is a healthcare technology company founded in 2020 and based in Saratoga, California. The company develops intelligent embedded virtualized clinical care software tools designed to assist healthcare specialists, including neurologists and primary care physicians, in understanding medical situations and making informed clinical decisions. Story Health's platform utilizes data from high-frequency sources to enhance therapy management through virtual protocols and adaptive machine learning. By focusing on patient-centered design, Story Health aims to bridge the gap between clinical evidence and real-world patient experiences, enabling clinicians to effectively address the physiological effects of disease and therapy.
Scipher Medicine
Series D in 2022
Scipher Medicine develops a molecular technology platform that predicts patient responsiveness to specific drugs in cardiovascular and autoimmune diseases. Its flagship product, PrismRA, identifies rheumatoid arthritis patients unlikely to respond to anti-TNF therapies, enabling alternative treatments. The company aims to transform drug prescription by predicting optimal therapy using simple blood samples.
Ori Biotech
Series B in 2022
Ori Biotech develops a manufacturing platform designed to accelerate the production of cell and gene therapies. Its proprietary system automates and standardizes manufacturing processes, enabling therapeutics developers to efficiently bring lifesaving treatments to patients.
Garuda Therapeutics
Series A in 2021
Garuda Therapeutics develops off-the-shelf hematopoietic stem cell therapies to treat life-threatening diseases. It seeks to eliminate dependency on donor or patient cells for blood stem cell transplants, leveraging a platform technology that generates off-the-shelf, self-renewing blood stem cells that are HLA-compatible and transgene-free, providing patients with rapid and broad access to durable therapies.
Elephas is a company focused on revolutionizing cancer treatment through its innovative live tumor imaging diagnostics platform. By leveraging advances in cancer biology, multimodal microscopy, engineering, and artificial intelligence, Elephas aims to enhance clinical decision-making and personalize therapy for cancer patients. The company's approach involves the use of human live tumor fragments, allowing clinicians to determine the most effective treatment strategies for individual patients. In doing so, Elephas not only seeks to improve patient outcomes but also to expedite the drug development process, addressing the significant challenges faced in oncology.
Vigil Neuroscience
Series B in 2021
Vigil Neuroscience is a clinical-stage biotechnology company focused on developing therapeutics that restore the function of microglia, the brain's immune cells. The company aims to improve outcomes for patients with neurodegenerative diseases by advancing its lead monoclonal antibody TREM2 agonist through Phase 1 trials and progressing its small molecule TREM2 agonist towards an Investigational New Drug (IND) application.
Slingshot Biosciences
Series A in 2021
Slingshot Biosciences develops engineered synthetic cells to accelerate drug research and enable diagnostics and therapeutics. The company creates next-generation cellular tools that aim to simplify complex experiments, improve data standardization in cell analysis, and provide cost-effective solutions for research programs. Its work includes aligning cellular properties such as forward and side scatter of white blood cells to enable more consistent measurements and faster interpretation. By removing cold-chain barriers, Slingshot Biosciences seeks to broaden access to advanced diagnostics and therapeutics, supporting programs focused on neglected and rare diseases. Operating in the industrial synthetic biology space, the company concentrates on practical cellular technologies that can shorten development timelines and reduce costs for researchers.
CAMP4 Therapeutics
Series A in 2021
CAMP4 Therapeutics Corporation is a bioinformatics company founded in 2015 and based in Cambridge, Massachusetts. The company specializes in gene regulation circuitry, focusing on the fundamental causes of diseases by manipulating gene expression. Utilizing its proprietary 4-D gene circuitry platform, CAMP4 codifies the activation of approximately 24,000 human genes into a discrete set of combinatorial rules based on existing cellular signaling pathways. This innovative approach allows CAMP4 to effectively control gene production, thereby accelerating the development of new therapies. By employing this technology, the company aims to streamline the drug development process, significantly reducing both the time and risks associated with bringing new medicines to patients.
Hawthorne Effect
Series A in 2021
Hawthorne Effect facilitates accessible clinical trials worldwide. It employs a Visit Management System that respects sponsor-investigator relationships, promotes shared technology for protocol compliance, and deploys trained healthcare providers ('HEROs') for patient visits anytime, anywhere, minimizing 'lost to follow-up' cases.
Faro Health
Series A in 2021
Faro Health develops a cloud-based medical platform that standardizes, automates, and streamlines clinical trial processes. Its system handles administrative burdens, allowing clinical researchers to focus on critical decisions that drive clinical value.
Isolere Bio
Seed Round in 2021
Isolere Bio, established in 2018, is a healthcare company specializing in biotherapeutic purification. Its core business involves simplifying and optimizing the manufacturing process of monoclonal antibodies and Adeno-Associated Viruses (AAVs) using Tangential Flow Filtration (TFF) technology. This streamlined approach aims to enhance global access to these vital drugs and research tools, while facilitating a seamless transition from laboratory-scale production to industrial-level output.
Ultivue develops multiplex biomarker assays for tissue phenotyping and digital pathology. Its products enable high-resolution fluorescent microscopy imaging, aiding life science research and potential clinical diagnostics.
VieCure develops an AI-driven platform that transforms cancer care by providing personalized, evidence-based treatment plans. It curates global cancer knowledge and tailors it to each patient's unique needs, ensuring compliance with national standards and genomic guidelines.
Scipher Medicine
Series C in 2021
Scipher Medicine develops a molecular technology platform that predicts patient responsiveness to specific drugs in cardiovascular and autoimmune diseases. Its flagship product, PrismRA, identifies rheumatoid arthritis patients unlikely to respond to anti-TNF therapies, enabling alternative treatments. The company aims to transform drug prescription by predicting optimal therapy using simple blood samples.
Personal Genome Diagnostics
Series C in 2021
Personal Genome Diagnostics, Inc. is a biotechnology company focused on patient-specific analyses of cancer genomes. Established in 2010 and headquartered in Baltimore, Maryland, the company has pioneered technologies for non-invasive "liquid biopsy" approaches, allowing for the detection of tumor-specific alterations in circulating cell-free DNA. Its offerings include the METDetect Assay for identifying MET gene amplifications, LungSelect for detecting actionable genetic alterations in non-small cell lung cancer patients, and PGDx elio plasma resolve, which analyzes various genetic mutations from plasma samples. Additionally, Personal Genome Diagnostics provides RNAcomplete, enabling researchers to extract both RNA and genomic DNA from a single tissue sample, and CancerXOME, which captures and analyzes coding regions of genes. The company collaborates with institutions like Mayo Clinic and partners with KingMed Diagnostics to enhance its research and diagnostic capabilities, thereby empowering oncologists and researchers with crucial genomic insights to combat cancer.
Syapse
Venture Round in 2021
Syapse, Inc. is a technology company that specializes in precision medicine through its innovative software platform, which aggregates and analyzes clinical, molecular, treatment, and outcomes data. Founded in 2008 and headquartered in San Francisco, California, with an additional office in Radnor, Pennsylvania, Syapse aims to enhance healthcare by providing actionable insights that support data-driven decision-making in precision oncology. The company operates the Syapse Learning Health Network, a global network that enables health systems and life sciences collaborators to share real-world cancer data. This network empowers healthcare organizations to collaborate effectively, ensuring that oncologists and decision-makers have access to comprehensive patient insights at the point of care, ultimately driving improved outcomes for cancer patients. Syapse has established strategic partnerships, including a collaboration with Pfizer, to further its mission of delivering personalized care based on robust real-world evidence.
Aro Biotherapeutics
Series A in 2020
Aro Biotherapeutics is a biotechnology company based in Philadelphia, Pennsylvania, focused on developing a novel protein drug platform known as Centyrins. These small, non-antibody protein scaffolds are designed to enhance treatment efficacy and safety for patients with cancer and other serious diseases. Aro Biotherapeutics has established a wholly-owned pipeline of Centyrins targeted at oncology and immunology applications. The unique structure of Centyrins allows for multi-specificity and the targeted delivery of complex drug payloads, including nucleic acids, which may aid in advancing therapeutic mechanisms and unlocking the potential of genetic medicines. Established in 2017, the company aims to innovate treatments that improve patient outcomes in challenging medical conditions.
Octave is a clinical platform developer focused on transforming the care landscape for multiple sclerosis and other neurodegenerative diseases. The company creates a platform that generates, analyzes, and integrates data to improve patient outcomes and reduce overall healthcare costs. By optimizing medication usage and healthcare services, Octave aims to enhance the efficiency of the pharmaceutical industry throughout the entire lifecycle of drug development, which includes discovery, clinical trials, and post-marketing phases. Their approach utilizes real-world evidence to inform decision-making, ultimately striving to set a new standard in multiple sclerosis care.
Vigil Neuroscience
Series A in 2020
Vigil Neuroscience is a clinical-stage biotechnology company focused on developing therapeutics that restore the function of microglia, the brain's immune cells. The company aims to improve outcomes for patients with neurodegenerative diseases by advancing its lead monoclonal antibody TREM2 agonist through Phase 1 trials and progressing its small molecule TREM2 agonist towards an Investigational New Drug (IND) application.
ArtisanBio
Series A in 2020
ArtisanBio is a developer of cell engineering and data analysis solutions aimed at advancing cell therapies for various human health applications. The company's innovative platform allows partners to optimize candidate designs for cell therapies, enhancing their safety and efficacy. By focusing on rapid discovery, performance in editing, and data analytics, ArtisanBio provides customizable solutions that address the complexities of next-generation cellular therapies. Through strategic collaborations with other innovators, ArtisanBio seeks to facilitate the development and delivery of precision-engineered cells, ultimately supporting healthcare providers in generating effective therapeutic options.
Ori Biotech
Series A in 2020
Ori Biotech develops a manufacturing platform designed to accelerate the production of cell and gene therapies. Its proprietary system automates and standardizes manufacturing processes, enabling therapeutics developers to efficiently bring lifesaving treatments to patients.
Triumvira Immunologics
Series A in 2020
Triumvira Immunologics USA, Inc. is an immunotherapy company founded in 2015 and headquartered in Austin, Texas, with research facilities in Hamilton, Canada. The company focuses on developing innovative T cell therapies aimed at improving cancer treatment outcomes. Its primary offerings include chimeric antigen receptor (CAR) therapies and engineered T cell receptor (TCR) therapies. A key aspect of Triumvira's approach is its proprietary T cell Antigen Coupler (TAC) technology, which recruits the entire natural T cell receptor and operates independently of the major histocompatibility complex (MHC). This technology enables the development of more effective therapies for a wider array of patients suffering from both solid and liquid malignancies, as well as other diseases beyond cancer.
DNAnexus, Inc. is a cloud-based provider of genome informatics and data management tools, primarily serving enterprises and organizations involved in genomic medicine. Founded in 2009 and headquartered in Mountain View, California, the company offers a platform that facilitates the analysis of raw sequencing data and the integration of genomic data with clinical information. Its suite of products includes MOSAIC Microbiome for collaborative research on the human microbiome, DNAnexus Apollo for clinico-genomic data exploration, and DNAnexus Titan for data analysis. Additionally, the DNAnexus Portals provide secure online workspaces for cross-disciplinary collaboration, while the Clinico-Genomic Data Solution addresses the need for disease-specific datasets through partnerships with healthcare providers. The company has established itself as a key player in the biopharmaceutical, diagnostic, and academic research sectors, enabling clients to tackle complex challenges in human health with enhanced security and scalability. DNAnexus also maintains a strategic alliance with WuXi NextCODE Genomics and has locations in San Francisco, London, and Prague.
SpeeDx is a company that specializes in molecular diagnostic solutions, offering advanced testing systems that provide comprehensive information for enhanced patient management. Utilizing innovative real-time polymerase chain reaction (qPCR) technology, SpeeDx develops market-leading multiplex detection and priming strategies. Its product portfolio includes diagnostics for sexually transmitted infections (STIs), antibiotic resistance markers, and respiratory diseases. By focusing on multiplex systems, SpeeDx enables healthcare providers to efficiently test for various infectious diseases and assess antibiotic resistance, thereby improving clinical decision-making and patient outcomes.
IsoPlexis
Series C in 2020
IsoPlexis is a life science technology company based in Branford, Connecticut, established in 2013. It specializes in developing a single-cell detection system that identifies a wide array of patient immune responses at the single-cell level. The company's platform focuses on cell-based proteomic systems and biomarkers, allowing for the assessment of therapeutic safety and efficacy, monitoring of disease progression, and exploration of functional protein biology and cellular signaling networks. IsoPlexis's technology enables clients to predict cancer patient responses to various novel immunotherapies and cellular therapies, thereby enhancing therapeutic development and informing clinical decision-making.
IsoPlexis
Series C in 2019
IsoPlexis is a life science technology company based in Branford, Connecticut, established in 2013. It specializes in developing a single-cell detection system that identifies a wide array of patient immune responses at the single-cell level. The company's platform focuses on cell-based proteomic systems and biomarkers, allowing for the assessment of therapeutic safety and efficacy, monitoring of disease progression, and exploration of functional protein biology and cellular signaling networks. IsoPlexis's technology enables clients to predict cancer patient responses to various novel immunotherapies and cellular therapies, thereby enhancing therapeutic development and informing clinical decision-making.
SeLux Diagnostics
Series B in 2019
SeLux Diagnostics, Inc. is a biotechnology company based in Charlestown, Massachusetts, focused on developing a next-generation phenotyping platform for antibiotic susceptibility testing and diagnostics of infectious diseases. Established in 2014, the company utilizes synthetic amplifier technology to enhance the speed and complexity of antibiotic susceptibility testing, thereby significantly improving patient care. By facilitating the rapid selection of personalized antimicrobial therapies, SeLux aims to transform the management of infectious diseases, ultimately saving lives, reducing hospital stays, and combating the growing issue of antibiotic resistance through more targeted treatments.
SpeeDx is a company that specializes in molecular diagnostic solutions, offering advanced testing systems that provide comprehensive information for enhanced patient management. Utilizing innovative real-time polymerase chain reaction (qPCR) technology, SpeeDx develops market-leading multiplex detection and priming strategies. Its product portfolio includes diagnostics for sexually transmitted infections (STIs), antibiotic resistance markers, and respiratory diseases. By focusing on multiplex systems, SpeeDx enables healthcare providers to efficiently test for various infectious diseases and assess antibiotic resistance, thereby improving clinical decision-making and patient outcomes.
SpeeDx is a company that specializes in molecular diagnostic solutions, offering advanced testing systems that provide comprehensive information for enhanced patient management. Utilizing innovative real-time polymerase chain reaction (qPCR) technology, SpeeDx develops market-leading multiplex detection and priming strategies. Its product portfolio includes diagnostics for sexually transmitted infections (STIs), antibiotic resistance markers, and respiratory diseases. By focusing on multiplex systems, SpeeDx enables healthcare providers to efficiently test for various infectious diseases and assess antibiotic resistance, thereby improving clinical decision-making and patient outcomes.
Ultivue develops multiplex biomarker assays for tissue phenotyping and digital pathology. Its products enable high-resolution fluorescent microscopy imaging, aiding life science research and potential clinical diagnostics.
IsoPlexis
Series C in 2019
IsoPlexis is a life science technology company based in Branford, Connecticut, established in 2013. It specializes in developing a single-cell detection system that identifies a wide array of patient immune responses at the single-cell level. The company's platform focuses on cell-based proteomic systems and biomarkers, allowing for the assessment of therapeutic safety and efficacy, monitoring of disease progression, and exploration of functional protein biology and cellular signaling networks. IsoPlexis's technology enables clients to predict cancer patient responses to various novel immunotherapies and cellular therapies, thereby enhancing therapeutic development and informing clinical decision-making.
Scipher Medicine
Series B in 2019
Scipher Medicine develops a molecular technology platform that predicts patient responsiveness to specific drugs in cardiovascular and autoimmune diseases. Its flagship product, PrismRA, identifies rheumatoid arthritis patients unlikely to respond to anti-TNF therapies, enabling alternative treatments. The company aims to transform drug prescription by predicting optimal therapy using simple blood samples.
Candel Therapeutics
Series C in 2019
Candel Therapeutics is a clinical-stage biopharmaceutical company dedicated to developing and commercializing innovative cancer immunotherapies aimed at improving the lives of cancer patients and their families. The company specializes in viral immunotherapies that utilize genetically modified adenoviruses and herpes simplex virus constructs to target cancer effectively. Candel's approach focuses on preventing the recurrence and progression of cancer with low toxicity, making it particularly suitable for treating less aggressive or slower-growing cancers, such as newly diagnosed prostate cancer. By enhancing treatment outcomes and facilitating faster recovery for patients, Candel Therapeutics strives to make a meaningful impact in the field of oncology.
Founded in 2015, Teckro is a life science technology company based in Limerick, Ireland. It offers a solution that transforms clinical trials by instantly connecting all relevant stakeholders and sharing knowledge, reducing burden on study personnel. The company serves pharmaceutical companies and clinical researchers globally.
SeLux Diagnostics
Series B in 2018
SeLux Diagnostics, Inc. is a biotechnology company based in Charlestown, Massachusetts, focused on developing a next-generation phenotyping platform for antibiotic susceptibility testing and diagnostics of infectious diseases. Established in 2014, the company utilizes synthetic amplifier technology to enhance the speed and complexity of antibiotic susceptibility testing, thereby significantly improving patient care. By facilitating the rapid selection of personalized antimicrobial therapies, SeLux aims to transform the management of infectious diseases, ultimately saving lives, reducing hospital stays, and combating the growing issue of antibiotic resistance through more targeted treatments.
Farcast Biosciences, established in 2019, is a clinical diagnostic company based in Boston, Massachusetts, with operations in Bangalore, India. The company specializes in developing and utilizing a proprietary Human Tumor Micro Dynamics (HTMD) platform. This platform preserves the natural state of human tumors through the culture of fresh, unmodified tumor fragments, creating a human tumor microenvironment. Farcast's technology enables oncologists to evaluate individual tumors and predict patient response to treatments before initiating therapy. Additionally, it serves drug developers and researchers by providing accurate and precise models for testing and analysis, facilitating the development of personalized cancer therapies.
SeLux Diagnostics
Venture Round in 2018
SeLux Diagnostics, Inc. is a biotechnology company based in Charlestown, Massachusetts, focused on developing a next-generation phenotyping platform for antibiotic susceptibility testing and diagnostics of infectious diseases. Established in 2014, the company utilizes synthetic amplifier technology to enhance the speed and complexity of antibiotic susceptibility testing, thereby significantly improving patient care. By facilitating the rapid selection of personalized antimicrobial therapies, SeLux aims to transform the management of infectious diseases, ultimately saving lives, reducing hospital stays, and combating the growing issue of antibiotic resistance through more targeted treatments.