iSelect Fund Management, LLC is a venture capital firm founded in 2014 and based in St. Louis, Missouri. The firm specializes in early-stage investments, focusing on series seed, A, and B rounds, and targets various sectors, including agriculture, healthcare, resource efficiency, education services, B2B software, and energy. In agriculture, iSelect emphasizes plant sciences, seed genetics, and sustainability, while in healthcare, it prioritizes immunotherapy and personalized medicine. The firm primarily invests in companies based in the United States, particularly in the Midwest and South, and also considers opportunities in India. iSelect seeks to make meaningful investments that address significant global challenges, such as healthcare costs and food security, with a minimum investment threshold of $0.05 million and a preference for a holding period of five to seven years or longer.
Holobiome is a biotechnology company based in Cambridge, Massachusetts, focused on developing microbiome-based therapeutics for treating diseases of the enteric and central nervous systems. Established in 2015, the company aims to address mental health issues such as depression and anxiety by leveraging the gut-brain axis through next-generation probiotics. By mapping and manipulating the human gut microbiome, Holobiome provides healthcare providers with innovative interventions that enhance patient recovery and improve metabolic and immune responses, all while minimizing pain and suffering associated with these conditions.
Triplebar
Venture Round in 2023
Triplebar provides sustainability, biotechnology, and synthetic biology research.
Mend
Series A in 2023
MEND is a life sciences company dedicated to advancing health and recovery through targeted clinical nutrition and medical food interventions. The company focuses on researching and developing products that enhance patient outcomes in various contexts, including injury recovery, surgical recovery, aging, and physical performance. MEND's solutions have been widely adopted by hospitals, health systems, and professional sports teams across major leagues, as well as by the elite forces of the US Military. Through its commitment to ongoing research and development, MEND aims to empower caregivers and improve health outcomes for individuals facing diverse health challenges.
Flywheel.io
Series D in 2023
Flywheel.io is a cloud-based data management platform tailored for biomedical research and collaboration. Founded in 2012 and headquartered in Minneapolis, Minnesota, the company provides a suite of tools designed to enhance the workflow of scientists and researchers. Its platform supports medical imaging, scientific computation, and content management, enabling users to capture, manage, and analyze research data efficiently. By utilizing cloud scalability and automation, Flywheel facilitates collaborative research, machine learning applications, and multicenter studies, which help organizations streamline their research processes. The platform, featuring a modern web interface and extensible compute engine, aims to eliminate bottlenecks in innovation, allowing researchers to focus on scientific discovery rather than IT challenges.
Pluton Biosciences
Series A in 2023
Pluton Biosciences specializes in the testing and discovery of microbes to develop a range of products, with a primary focus on biopesticides and pharmaceuticals. The company's innovative platform is designed to mine and clone various microbes, facilitating the production of sustainable and all-natural bioproducts. By concentrating on applications in biopesticides, crop protection, human health, and bioremediation, Pluton Biosciences aims to enable researchers to explore new methodologies for utilizing bacteria, fungi, and viruses in the manufacturing of effective and eco-friendly solutions.
Harpe Bio
Convertible Note in 2023
Harpe Bioherbicide Solutions is a Raleigh-based company that provides sustainable weed-management solutions for organic and industrial agriculture. Harpe Bio's technologies deliver natural crop protection by utilizing a variety of plant extracts. The plant extracts serve as a platform that may be tailored to various weed management circumstances. Harpe's herbicide platform can be used alone or in conjunction with any currently marketed herbicide. Harpe's new modes and areas of action will improve synthetic herbicide efficacy, including the reduction of resistant weed populations.
Mercy BioAnalytics
Series A in 2023
Mercy BioAnalytics is a biotechnology company based in Natick, Massachusetts, founded in 2018 by Paul Blavin and Joseph Sedlak. The company focuses on improving cancer outcomes through early detection by utilizing a novel liquid biopsy assay platform. This platform analyzes tumor-derived extracellular vesicles (EVs), which are abundant in blood and provide critical information about their parent cells. By leveraging these EVs, Mercy BioAnalytics aims to enable the detection of various types of cancer at its earliest stages, ultimately striving to enhance patient outcomes and save lives.
Growers Edge
Series B in 2023
Growers Edge is a company focused on enhancing grower profitability through innovative, data-driven financial technology solutions tailored for the agricultural sector. By addressing financial gaps faced by farmers, the company transforms the sale of agricultural inputs and services, enabling farmers to adopt new technologies that enhance their profitability. Utilizing data science, public and private datasets, and advanced algorithms, Growers Edge develops warranty-backed crop management plans. These plans provide agricultural retailers and lenders with integrated financial products, white-labeled lending and credit decision platforms, and land valuation tools. Headquartered in Johnston, Iowa, the company is led by a team of experienced crop management professionals and supported by prominent investors in the agtech industry.
EarthOptics
Series B in 2023
EarthOptics is a developer of a global soil cloud platform aimed at sustainable agricultural management. The company utilizes advanced sensors and machine learning techniques to create highly accurate soil maps based on minimal soil samples. Its technology provides insights into various soil attributes, including compaction, fertility, and carbon levels. This information enables farmers, ranchers, and land managers to make informed and sustainable soil management decisions, which can lead to improved profitability and environmental stewardship. Additionally, EarthOptics offers near-real-time actionable data that enhances soil health management and provides cost-effective verification for carbon credits.
AgriWebb
Series B in 2022
AgriWebb is a software company specializing in the livestock production sector, offering a cloud-based farm management platform that facilitates real-time data collection and analysis. The platform enables farmers to track livestock actions, manage paddock treatments, and record crop information, all while maintaining transparency and efficiency. AgriWebb's tools support farmers in making informed decisions by providing essential insights into their operations, whether online or offline. Founded by a team with five generations of livestock production experience, AgriWebb aims to revolutionize the industry through data-driven practices, enhancing management efficiency and fostering better integration across supply chains.
Vestaron
Series C in 2022
Vestaron Corporation specializes in the development, manufacture, and sale of peptide-based biologic crop protection products. Founded in 2005 and headquartered in Durham, North Carolina, with a research and development center in Kalamazoo, Michigan, Vestaron offers a range of bioinsecticides including Spear-T, Spear-Lep, and Leprotec, which target various pests in vegetables, fruits, and field crops. The company aims to enhance crop safety, efficacy, and sustainability by providing biopesticides that address resistance issues while ensuring safety for workers and the environment. Vestaron has received notable accolades for its innovative solutions, including the Bernard Blum Award and the Green Chemistry Challenge Award, recognizing its commitment to environmental stewardship and effective crop protection.
Bond Pet Foods
Venture Round in 2022
Bond Pet Foods is a Boulder, Colorado-based company that specializes in creating sustainable pet food products using biotechnology. Founded in 2015, the company develops meat proteins derived from animal cells without the need for animal slaughter, and utilizes fermentation processes similar to those found in craft brewing. The proteins are cultivated in fermentation tanks and are supplemented with a nutrient-rich broth containing vitamins, sugars, and minerals, ensuring they meet the nutritional needs of companion animals. By offering all-natural and animal-free alternatives, Bond Pet Foods aims to provide environmentally friendly options for pet owners while supplying its innovative ingredients to pet food manufacturers for incorporation into their recipes and product lines.
Vestaron
Series C in 2022
Vestaron Corporation specializes in the development, manufacture, and sale of peptide-based biologic crop protection products. Founded in 2005 and headquartered in Durham, North Carolina, with a research and development center in Kalamazoo, Michigan, Vestaron offers a range of bioinsecticides including Spear-T, Spear-Lep, and Leprotec, which target various pests in vegetables, fruits, and field crops. The company aims to enhance crop safety, efficacy, and sustainability by providing biopesticides that address resistance issues while ensuring safety for workers and the environment. Vestaron has received notable accolades for its innovative solutions, including the Bernard Blum Award and the Green Chemistry Challenge Award, recognizing its commitment to environmental stewardship and effective crop protection.
Brightseed
Series B in 2022
Brightseed, Inc. is a biotechnology company based in San Francisco, California, that specializes in the discovery of bioactive compounds in plants to enhance human health. Utilizing its advanced Forager platform, which employs artificial intelligence and machine learning algorithms, Brightseed accelerates the identification and validation of clinically beneficial molecules. This innovative approach enables the company to uncover connections between natural compounds and health outcomes, revealing the potential of bioactives that have previously remained uncharted. By integrating these discoveries back into the food supply chain, Brightseed collaborates with various companies across the consumer health continuum to develop science-backed health solutions aimed at managing chronic diseases and improving overall quality of life. Founded in 2017, Brightseed is committed to exploring the untapped resources of the plant kingdom to address pressing health challenges.
One.bio
Series A in 2022
One.bio is a biotechnology spinout from UC Davis that specializes in developing naturally-derived oligosaccharides for applications in food, agriculture, and biopharmaceuticals. Utilizing proprietary technology, the company creates innovative ingredients aimed at modulating the microbiome and enhancing immune function. This focus allows One.bio to provide clients with access to novel prebiotics and therapies that support both human and animal health. By unlocking the benefits of nutrition, One.bio aims to contribute to improved longevity and overall well-being.
Harpe Bio
Series A in 2022
Harpe Bioherbicide Solutions is a Raleigh-based company that provides sustainable weed-management solutions for organic and industrial agriculture. Harpe Bio's technologies deliver natural crop protection by utilizing a variety of plant extracts. The plant extracts serve as a platform that may be tailored to various weed management circumstances. Harpe's herbicide platform can be used alone or in conjunction with any currently marketed herbicide. Harpe's new modes and areas of action will improve synthetic herbicide efficacy, including the reduction of resistant weed populations.
Kula Bio
Series A in 2022
Kula Bio specializes in sustainable, biological solutions for modern agriculture. It energizes nitrogen-fixing microbes to produce organic fertilizer. By rewiring the energy flow from the sun to soil, they are disrupting synthetic fertilizer to eliminate the division between affordable practices and stewardship of our land, sea, and air. The company was founded in 2018 and is headquartered in Somerville, Massachusetts.
Cyrus Biotechnology
Series B in 2021
Cyrus Biotechnology, Inc. specializes in developing software tools for protein structure prediction and design, aiming to enhance research in biotechnology and pharmaceuticals. The company's flagship product, Rosetta, allows for the design of biologically active proteins that can address critical health issues, such as brain cancer treatment and gluten breakdown in Celiac Disease patients. Additionally, Cyrus Bench offers an enterprise version of the Rosetta toolkit, equipped with a variety of bio-molecular computation tools. The company also provides Cyrus CryoEM services, which include advanced structure refinement and model building. Founded in 2014 and headquartered in Seattle, Washington, Cyrus Biotechnology serves a diverse clientele, including pharmaceutical companies, venture-backed startups, and mid-sized biotech firms focused on therapeutic discovery and industrial biotechnology innovation.
EarthOptics
Series A in 2021
EarthOptics is a developer of a global soil cloud platform aimed at sustainable agricultural management. The company utilizes advanced sensors and machine learning techniques to create highly accurate soil maps based on minimal soil samples. Its technology provides insights into various soil attributes, including compaction, fertility, and carbon levels. This information enables farmers, ranchers, and land managers to make informed and sustainable soil management decisions, which can lead to improved profitability and environmental stewardship. Additionally, EarthOptics offers near-real-time actionable data that enhances soil health management and provides cost-effective verification for carbon credits.
Flywheel.io
Series C in 2021
Flywheel.io is a cloud-based data management platform tailored for biomedical research and collaboration. Founded in 2012 and headquartered in Minneapolis, Minnesota, the company provides a suite of tools designed to enhance the workflow of scientists and researchers. Its platform supports medical imaging, scientific computation, and content management, enabling users to capture, manage, and analyze research data efficiently. By utilizing cloud scalability and automation, Flywheel facilitates collaborative research, machine learning applications, and multicenter studies, which help organizations streamline their research processes. The platform, featuring a modern web interface and extensible compute engine, aims to eliminate bottlenecks in innovation, allowing researchers to focus on scientific discovery rather than IT challenges.
Sentera
Series C in 2021
Sentera, Inc. specializes in designing, manufacturing, and distributing integrated software and sensor products primarily for the agriculture sector, along with applications in mining, infrastructure, security, and public safety. Founded in 2014 and based in Minneapolis, the company offers advanced technologies including drone sensors and video services, as well as the OnTop mobile app and desktop client for inspections. Sentera employs machine learning and data science to provide decision support and insights, enabling growers, advisors, and enterprise customers to optimize cultivation outcomes. By leveraging high-resolution drone imagery, satellite data, and other sensor inputs, Sentera delivers reliable plant-level measurements and analytics that facilitate informed decision-making and improved performance in agricultural practices.
Kula Bio
Seed Round in 2021
Kula Bio specializes in sustainable, biological solutions for modern agriculture. It energizes nitrogen-fixing microbes to produce organic fertilizer. By rewiring the energy flow from the sun to soil, they are disrupting synthetic fertilizer to eliminate the division between affordable practices and stewardship of our land, sea, and air. The company was founded in 2018 and is headquartered in Somerville, Massachusetts.
Molecular Assemblies
Series A in 2021
Molecular Assemblies, Inc. is a San Diego-based company specializing in enzymatic DNA synthesis technology, which facilitates the development of DNA-based products across various industries. Founded in 2013, the company focuses on creating long, high-quality, sequence-specific DNA in a reliable, affordable, and sustainable manner, inspired by natural processes. Its technology has applications in industrial synthetic biology, personalized therapeutics, precision diagnostics, information storage, nanotechnology, and DNA electronics. The firm boasts a skilled executive and scientific team, supported by a robust intellectual property portfolio. Molecular Assemblies has garnered investments from a range of venture capital sources, indicating strong interest in its innovative approach to DNA synthesis.
Pattern Ag
Venture Round in 2021
Pattern Ag specializes in soil microbiome analysis, offering farmers insights to optimize their agricultural inputs. The company's precision agriculture platform utilizes high-resolution mapping of soil DNA to provide actionable intelligence tailored to the specific pest and disease challenges faced by corn and soybean farmers. By delivering recommendations on crop protection, seed selection, and fertility needs, Pattern Ag helps farmers make informed decisions about what to purchase and when to apply these solutions. This focus on data-driven insights not only aims to enhance crop yields but also to improve overall farm productivity and sustainability.
Stony Creek Colors
Series B in 2021
Stony Creek Colors, Inc. is a manufacturer of bio-based colorants specifically designed for the textile industry. Founded in 2012 and based in Springfield, Tennessee, the company collaborates with small farmers in the Southeast U.S. to produce plant-based dyes, including indigo. Stony Creek Colors aims to provide clean and safe natural dyes that replace hazardous chemicals traditionally used in textile manufacturing. By focusing on sustainable practices, the company enables the textile and fashion industries to offer environmentally conscious premium products to consumers.
Benson Hill
Series D in 2020
Benson Hill is a crop improvement company that unlocks the natural diversity of plants and empowers innovators with a revolutionary crop design platform to develop healthier and more sustainable food and ingredients. Benson Hill empowers innovators to develop more healthy, flavorful, and sustainable food by unlocking the natural genetic diversity of plants. Benson Hill’s CropOS™ platform combines machine learning and big data with breeding techniques and plant biology to drastically accelerate and simplify the product development process.
TradeLanes
Seed Round in 2020
TradeLanes is a technology company based in Oakland, California, founded in 2015. It offers a software-as-a-service (SaaS) platform that automates and digitizes supply chain processes for traders, shippers, and merchants. The platform connects various participants in international trade, allowing them to collaborate seamlessly through a single document chain throughout the lifecycle of a shipment. By integrating demand planning, supplier performance, inventory management, and logistics into one application, TradeLanes aims to streamline global trade operations and reduce costs associated with supply chain management. The company's mission is to facilitate frictionless global trade for all involved parties.
One.bio
Venture Round in 2020
One.bio is a biotechnology spinout from UC Davis that specializes in developing naturally-derived oligosaccharides for applications in food, agriculture, and biopharmaceuticals. Utilizing proprietary technology, the company creates innovative ingredients aimed at modulating the microbiome and enhancing immune function. This focus allows One.bio to provide clients with access to novel prebiotics and therapies that support both human and animal health. By unlocking the benefits of nutrition, One.bio aims to contribute to improved longevity and overall well-being.
MOBILion Systems
Series A in 2019
MOBILion Systems is a biotechnology company that specializes in identifying and analyzing the most challenging molecules that other instruments fail to detect. Its technology focuses on biologic therapeutics, discovering biomarkers, and improving the accuracy of diagnostic tests.MOBILion’s technology makes it easy to separate, identify, and analyze the most challenging molecules that other instruments fail to detect. The company's analytical instruments provide unprecedented sensitivity, resolution, and throughput that will fuel the development of better therapeutics, the ability to detect disease earlier, and the power to attack diseases at their roots instead of their symptoms.
Benson Hill
Series C in 2019
Benson Hill is a crop improvement company that unlocks the natural diversity of plants and empowers innovators with a revolutionary crop design platform to develop healthier and more sustainable food and ingredients. Benson Hill empowers innovators to develop more healthy, flavorful, and sustainable food by unlocking the natural genetic diversity of plants. Benson Hill’s CropOS™ platform combines machine learning and big data with breeding techniques and plant biology to drastically accelerate and simplify the product development process.
Benson Hill
Series C in 2018
Benson Hill is a crop improvement company that unlocks the natural diversity of plants and empowers innovators with a revolutionary crop design platform to develop healthier and more sustainable food and ingredients. Benson Hill empowers innovators to develop more healthy, flavorful, and sustainable food by unlocking the natural genetic diversity of plants. Benson Hill’s CropOS™ platform combines machine learning and big data with breeding techniques and plant biology to drastically accelerate and simplify the product development process.
HerdDogg
Seed Round in 2018
HerdDogg is a global herd health and data science platform. It is a two-part system that helps ranchers track health and proximity data from their herd. The company's device gathers the data captured by the ear tags and reports it directly to the rancher via an app or web database.
Shield Bio
Series A in 2018
Shield Bio focuses on combating antibiotic resistance, which is projected to surpass cancer as a leading cause of death by 2050. With infections like gonorrhea becoming resistant to numerous antibiotics, resulting in over 820,000 new cases annually in the U.S., the urgency to address this crisis has escalated. Shield Bio has developed an innovative genomic testing platform that allows sexually transmitted infection (STI) clinics to identify antibiotic-resistant strains of pathogens. This technology enables healthcare providers to determine the most effective antibiotics for treatment, thereby improving patient outcomes and helping to prevent the further spread of antibiotic resistance. By enhancing the accuracy and speed of susceptibility testing, Shield Bio aims to tackle one of the most significant challenges in modern medicine.
Artemis
Corporate Round in 2018
Artemis develops a cultivation management platform designed for enterprise greenhouses, indoor farms, and high tunnel farms. This software enables growers to efficiently manage people, plants, processes, and compliance by providing a comprehensive view of facility productivity. Users can track operations and production data remotely through desktops, tablets, or smartphones. The platform allows owners and managers to oversee workflows, register crop batches, address food safety issues, manage personnel, and gain insights to enhance crop productivity. Founded in 2015 and originally named Agrilyst, the company rebranded to Artemis in May 2019 and is headquartered in Brooklyn, New York.
Bonumose
Series A in 2017
They created Bonumose as a new company in 2016 for the purpose of commercializing Dr. Daniel Wichelecki’s enzymatic technology breakthrough for the production of affordable, delicious, healthy tagatose. Since then, Bonumose has developed methods for producing affordable allulose, too, as well as other #goodsugars.Bonumose’s vision is to earn a place among the world’s most trusted food ingredient manufacturers. With a mindset of business as a moral imperative, Bonumose’s purpose includes:
Cofactor Genomics
Series A in 2017
Cofactor Genomics specializes in predictive immune modeling to enhance precision medicine by addressing existing barriers in the field. The company focuses on advancing the use of multidimensional biomarkers as opposed to single-analyte biomarkers through sophisticated health expression models. Cofactor operates one of the first CAP-certified clinical RNA sequencing laboratories, which facilitates efficient and cost-effective clinical trials for its partners. Leveraging its expertise in molecular biology, informatics, and database management, Cofactor Genomics provides high-quality services tailored to the healthcare and pharmaceutical sectors. This includes the development of diagnostic assays that target oncologic, immunologic, and neurodegenerative diseases, thereby contributing to medical research and improving patient outcomes.
Agrible
Series B in 2017
Agrible, Inc. is an agricultural technology company based in Champaign, Illinois, focused on developing software solutions to enhance farming operations globally. Founded in 2007 by Bill Northcott, Chris Harbourt, and Paul Miller, the company provides various tools to assist growers in making informed decisions. Its flagship product, Morning Farm Report, offers detailed forecasts and data on yield predictions, nutrient availability, and weather conditions, among other critical factors. Agrible also features Find My Seed, which aggregates third-party seed trial data, and Pocket Rain Gauge, delivering localized rainfall measurements. Other applications include Pocket Spray Smart, which provides field-specific spraying conditions, and Pocket Drone Control, which aids in crop damage assessments by offering aerial views of fields. Agrible serves a diverse clientele, including independent growers, major food brands, and agricultural consultants, enabling them to optimize production and sustainability through advanced predictive analytics and field-level insights.
Benson Hill
Series B in 2017
Benson Hill is a crop improvement company that unlocks the natural diversity of plants and empowers innovators with a revolutionary crop design platform to develop healthier and more sustainable food and ingredients. Benson Hill empowers innovators to develop more healthy, flavorful, and sustainable food by unlocking the natural genetic diversity of plants. Benson Hill’s CropOS™ platform combines machine learning and big data with breeding techniques and plant biology to drastically accelerate and simplify the product development process.
Holganix
Venture Round in 2017
Holganix, Inc. is a manufacturer of plant-based bio-stimulant soil supplements aimed at enhancing soil health and promoting sustainable plant growth. Founded in 2010 and headquartered in Glen Mills, Pennsylvania, the company offers a range of products including tree and shrub solutions, golf course treatments, agriculture products, and flower programs. A key offering is Holganix Bio 800+, which contains beneficial microorganisms, microbe food, and nutrient enhancers that optimize soil conditions. Holganix's products are designed to reduce fertilizer use by up to 90%, thereby lowering costs for landscape and lawn care companies while minimizing environmental impact. The company sells its products through distributors in the United States and also offers online sales.
Honcho
Seed Round in 2016
Honcho is the only AI-powered communications protection software that coaches and trains as employees type to help compliance and HR professionals build and maintain exceptional communications practices in their companies. Our communications-protection software helps reduce the risk of non-compliant communications. Detect when users are composing potentially problematic messages, have the ability to archive official communication channels, and support supervisory review of any issues that arise. Show employees, customers, and the world that you care about ensuring an ethical and compliant workplace. And, invest in your communications now to avoid costly litigation, regulatory fines, negative press, and a demoralized culture later.
Euclises Pharmaceuticals
Venture Round in 2016
Euclises Pharmaceuticals, Inc. is engaged in the research, development, and commercialization of innovative medicines targeting inflammation and oncology. Founded in 2011 and headquartered in Saint Louis, Missouri, the company focuses on creating novel pain and cancer medications that promise enhanced safety profiles compared to current therapies. The firm is built on pioneering inventions by Dr. John Talley, a renowned medicinal chemist known for developing Celebrex among other approved drugs. Euclises aims to introduce new compounds that provide improved efficacy and safety, positioning itself as a leader in the pharmaceutical industry. The company operates from the BioGenerator Accelerator Labs, where it continues to advance its research initiatives.
AmpliFund
Series A in 2016
AmpliFund provides a cloud-based grant management software solution that serves both grant makers and grant seekers, facilitating the entire grant life-cycle. The platform enables users to streamline processes, centralize data and documentation, and enhance both quantitative and qualitative reporting. By automating various activities throughout the grant management process, AmpliFund drives standardization, efficiency, transparency, and compliance, which are crucial for accountability in grant program outcomes. Founded by professionals with expertise in grant management, the company focuses on empowering state, local, and tribal governments to maximize their funding potential and create capacity within their teams. Through its innovative tools and resources, AmpliFund aims to simplify business processes and amplify grant resources to support impactful missions.
Bractlet
Venture Round in 2016
Bractlet, Inc. is an Austin, Texas-based company that specializes in developing an energy intelligence platform aimed at maximizing energy efficiency project value. Founded in 2011, Bractlet provides integrated hardware and software solutions designed to analyze business performance and reduce energy waste. Its hardware includes a commercial electrical panel that accommodates up to 42 branch circuits, while its measurement and verification software generates reports for stakeholders. The company also offers services related to building energy modeling and big data, positioning itself as a leader in optimizing building performance and enhancing capital investment in the real estate sector.
Kultevat
Venture Round in 2016
Kultevat, Inc. is a biotechnology company focused on the cultivation and processing of dandelion varieties to produce natural rubber. The company primarily works with TKS Dandelion, a domestic source of rubber in the United States, Canada, and Europe, and also extracts rubber from Russian Dandelion. Kultevat's offerings include latex and bulk rubber products used in a variety of applications such as gloves, medical devices, and automotive parts, as well as renewable food co-products and sugar feedstocks for biofuel production. Founded in 2013 and based in Portageville, Missouri, Kultevat aims to provide sustainable alternatives to synthetic rubber, contributing positively to agricultural markets and reducing environmental impact.
Epharmix
Seed Round in 2016
Epharmix is a digital healthcare company that creates clinically validated and condition-specific communication tools. It helps care teams automatically monitor underserved patients to improve care & reduce workload with interventions proven to impact engagement and outcomes. It was founded in 2015 and headquartered in St Louis, Missouri.
StreamLink Software
Venture Round in 2016
StreamLink Software-is a Software-as-a-Service company that develops grant management software for nonprofits and the public sector. Ther grants management solution, AmpliFund, is designed for managing every stage of the grant lifecycle and is at the forefront of automating grant compliance and data standardization in the public sector. It was founded in 2008 and is headquartered in Cleveland, Ohio.
Neuros Medical
Venture Round in 2016
Neuros Medical, Inc. is a neuromodulation company based in Willoughby Hills, Ohio, that specializes in developing proprietary neurostimulation therapies aimed at addressing unmet medical needs for patients globally. The company's flagship technology, known as Electrical Nerve Block, targets chronic pain conditions, including neuroma and residual limb pain, chronic post-surgical pain, and chronic migraine. Neuros Medical also offers the Neuros Altius System, which features an implantable generator with an integrated rechargeable battery, a cuff electrode, and associated external devices. Established in 2008, the company is dedicated to advancing innovative solutions for pain management.
Open Studio Network
Seed Round in 2015
Open Studio Network Access to premier musical artists, through a simple, interactive online lesson platform.
Mentor Spaces
Venture Round in 2015
Mentor Spaces is a community-focused mentorship platform aimed at helping companies attract, hire, and retain underrepresented talent. The platform serves as a networking space for underrepresented professionals, enabling them to connect with industry experts who share similar professional interests and goals. By fostering these relationships, Mentor Spaces allows companies to engage with diverse talent prior to formal recruitment events, enhancing their efforts to build a more inclusive workforce. Through its unique approach, the platform supports both individuals seeking mentorship and organizations looking to improve their diversity initiatives.
Antegrin Therapeutics
Seed Round in 2015
Antegrin Therapeutics, LLC, is a drug discovery and development company focused on the development of novel therapies for fibrotic diseases. Our lead program aims to develop a treatment for idiopathic pulmonary fibrosis, a progressive, life-threatening condition that currently has no FDA-approved medication.
Euclises Pharmaceuticals
Venture Round in 2015
Euclises Pharmaceuticals, Inc. is engaged in the research, development, and commercialization of innovative medicines targeting inflammation and oncology. Founded in 2011 and headquartered in Saint Louis, Missouri, the company focuses on creating novel pain and cancer medications that promise enhanced safety profiles compared to current therapies. The firm is built on pioneering inventions by Dr. John Talley, a renowned medicinal chemist known for developing Celebrex among other approved drugs. Euclises aims to introduce new compounds that provide improved efficacy and safety, positioning itself as a leader in the pharmaceutical industry. The company operates from the BioGenerator Accelerator Labs, where it continues to advance its research initiatives.
BenchmarkONE
Seed Round in 2015
BenchmarkONE develops sales and marketing automation software tailored for small and mid-sized businesses. The company offers an integrated platform that includes customer relationship management (CRM) tools and sales automation features, allowing users to monitor contacts' activities, track deals, manage communications, and segment their audience. Additionally, BenchmarkONE provides email marketing capabilities with a user-friendly drag-and-drop email builder and marketing automation tools designed to engage visitors, prioritize leads, and optimize campaign investments. Originally known as Hatchbuck, Inc., the company rebranded to BenchmarkONE in June 2020 and has been operational since 2010, with its headquarters in St. Louis, Missouri. As of September 2019, BenchmarkONE functions as a subsidiary of Benchmark Internet Group, LLC.
Bractlet
Seed Round in 2015
Bractlet, Inc. is an Austin, Texas-based company that specializes in developing an energy intelligence platform aimed at maximizing energy efficiency project value. Founded in 2011, Bractlet provides integrated hardware and software solutions designed to analyze business performance and reduce energy waste. Its hardware includes a commercial electrical panel that accommodates up to 42 branch circuits, while its measurement and verification software generates reports for stakeholders. The company also offers services related to building energy modeling and big data, positioning itself as a leader in optimizing building performance and enhancing capital investment in the real estate sector.
Ward Alternative Energy
Venture Round in 2015
Ward Alternative Energy was born from a passion to provide American, low cost, clean transportation fuels for vehicles. Discovering, producing and compressing natural gas in the field is a deep upstream expertise built over the past 50 years at Ward Petroleum. At Ward Alternative Energy, we add the down-stream natural gas, fueling and NGV expertise of our industry veterans. Our team is well prepared to be the natural gas fuels, station services and vehicle services provider and partner of choice for fleets. We started our business in Colorado in 2012 but are now expanding to Wyoming, New Mexico, northwest Texas and east through Kansas to St. Louis.
BenchmarkONE
Venture Round in 2015
BenchmarkONE develops sales and marketing automation software tailored for small and mid-sized businesses. The company offers an integrated platform that includes customer relationship management (CRM) tools and sales automation features, allowing users to monitor contacts' activities, track deals, manage communications, and segment their audience. Additionally, BenchmarkONE provides email marketing capabilities with a user-friendly drag-and-drop email builder and marketing automation tools designed to engage visitors, prioritize leads, and optimize campaign investments. Originally known as Hatchbuck, Inc., the company rebranded to BenchmarkONE in June 2020 and has been operational since 2010, with its headquarters in St. Louis, Missouri. As of September 2019, BenchmarkONE functions as a subsidiary of Benchmark Internet Group, LLC.
ImmunoPhotonics
Series A in 2015
ImmunoPhotonics, Inc. is a biotechnology company focused on developing innovative immunotherapy treatments for cancer, specifically targeting metastatic solid tumors. Founded in 2008 and located in Columbia, Missouri, the company has created a proprietary drug product designed to function as a minimally invasive therapeutic cancer vaccine. This product is administered through intratumoral injection following tumor ablation, leveraging tumor-associated neoantigens to stimulate a systemic anti-tumor immune response. By transforming the process of tumor ablation into a therapeutic approach, ImmunoPhotonics aims to enhance treatment options for patients with late-stage metastatic cancers. The company has also established a strategic partnership with Veterinary Cancer Therapeutics, LLC to further its mission in cancer treatment.
Kultevat
Venture Round in 2015
Kultevat, Inc. is a biotechnology company focused on the cultivation and processing of dandelion varieties to produce natural rubber. The company primarily works with TKS Dandelion, a domestic source of rubber in the United States, Canada, and Europe, and also extracts rubber from Russian Dandelion. Kultevat's offerings include latex and bulk rubber products used in a variety of applications such as gloves, medical devices, and automotive parts, as well as renewable food co-products and sugar feedstocks for biofuel production. Founded in 2013 and based in Portageville, Missouri, Kultevat aims to provide sustainable alternatives to synthetic rubber, contributing positively to agricultural markets and reducing environmental impact.
Gremlin Social
Seed Round in 2014
Gremlin Social offers organizational tools to streamline all of your social media marketing needs. Save time and money with Twitter, Facebook, and LinkedIn all in one easy-to-use dashboard. Engage with customers, search Twitter hashtags and brand mentions, and schedule your posts in as little as 15 minutes a day at the optimal time and frequency in each social network without leaving GremlinSocial.com. Gremlin Social employs a staff of experts who specialize in social media best practices. We offer services for our customers including strategy, training, analytics, and research (STAR). Gremlin Social Guardian is also endorsed by the American Bankers Association – through its subsidiary the Corporation for American Banking - and the New York Bankers Association (NYBA) as the recommended social media management and compliance toolkit for all member financial institutions. Products Gremlin Social offers enterprise and white label options for banks and financial services. Gremlin Social features include: team management, scheduled and recurring posts, keyword filtration, translation, branded reports, analytics, content libraries, Bit.ly and Brev.is link shorteners, and much more!
ImmunoPhotonics
Series A in 2014
ImmunoPhotonics, Inc. is a biotechnology company focused on developing innovative immunotherapy treatments for cancer, specifically targeting metastatic solid tumors. Founded in 2008 and located in Columbia, Missouri, the company has created a proprietary drug product designed to function as a minimally invasive therapeutic cancer vaccine. This product is administered through intratumoral injection following tumor ablation, leveraging tumor-associated neoantigens to stimulate a systemic anti-tumor immune response. By transforming the process of tumor ablation into a therapeutic approach, ImmunoPhotonics aims to enhance treatment options for patients with late-stage metastatic cancers. The company has also established a strategic partnership with Veterinary Cancer Therapeutics, LLC to further its mission in cancer treatment.
Time to Cater
Seed Round in 2014
Time To Cater is a web-based platform that helps companies and individuals coordinate their ideal catered even at NO EXTRA COST to client. If you have had to coordinate catering for events or if you need food ordered quickly online, and especially if you have done it consistently, you understand that valuable time is wasted calling potential caterers for availability, prices, and delivery details, etc. We fix this problem by providing a web-based platform and mobile app that helps companies and individuals coordinate their ideal catered event. Our client only has to submit their event details and budget to our web application and then show up for the event and enjoy! We take care of EVERYTHING in between. And the BEST part is that there is NO EXTRA COST to our client for our service! We make money by making a commission from the caterers in our Preferred Caterer Network.
CrazyForEducation
Seed Round in 2014
CrazyForEducation LLC is an educational technology company based in St. Louis, Missouri, founded in 2012 by Dr. Renato Cataldo. The company specializes in developing online teaching software and educational tools tailored for K-12 schools, teachers, students, and professionals. Its platform supports flip teaching by providing professional development resources, including recorded webinars and feedback videos for educators and students. Key features of the platform include tools for lesson assignments, digital note-taking, course management, and student organization. Additionally, CrazyForEducation offers uTutor.me, which allows users to access video lessons from K-12 and college educators, and ClinPharmEd, an online educational system for clinical pharmacists and pharmacy students. The company's mission is to enhance the educational experience through adaptive teaching models and comprehensive support for schools and districts.
Benson Hill
Seed Round in 2014
Benson Hill is a crop improvement company that unlocks the natural diversity of plants and empowers innovators with a revolutionary crop design platform to develop healthier and more sustainable food and ingredients. Benson Hill empowers innovators to develop more healthy, flavorful, and sustainable food by unlocking the natural genetic diversity of plants. Benson Hill’s CropOS™ platform combines machine learning and big data with breeding techniques and plant biology to drastically accelerate and simplify the product development process.
adFreeq
Seed Round in 2014
AdFreeq is a socially integrated classified ad service that brings buyers and sellers together in real-time. The platform allows companies to present all of their goods or services as a simple ad on any website. AdFreeq was founded in 2011 and is based in Columbia, Missouri, United States.
Tansna Therapeutics
Seed Round in 2014
Tansna Therapeutics, Inc. is a drug discovery and development company based in St. Louis, Missouri, founded in 2010. The company specializes in creating and commercializing oral drugs aimed at treating epilepsy and other central nervous system disorders. Its primary focus is on developing novel oral anticonvulsant agents designed to effectively reduce seizure frequency in patients with epilepsy. By providing safe and innovative treatment options, Tansna Therapeutics aims to enhance the quality of care for individuals suffering from these debilitating conditions.
Time to Cater
Angel Round in 2014
Time To Cater is a web-based platform that helps companies and individuals coordinate their ideal catered even at NO EXTRA COST to client. If you have had to coordinate catering for events or if you need food ordered quickly online, and especially if you have done it consistently, you understand that valuable time is wasted calling potential caterers for availability, prices, and delivery details, etc. We fix this problem by providing a web-based platform and mobile app that helps companies and individuals coordinate their ideal catered event. Our client only has to submit their event details and budget to our web application and then show up for the event and enjoy! We take care of EVERYTHING in between. And the BEST part is that there is NO EXTRA COST to our client for our service! We make money by making a commission from the caterers in our Preferred Caterer Network.
Tansna Therapeutics
Angel Round in 2013
Tansna Therapeutics, Inc. is a drug discovery and development company based in St. Louis, Missouri, founded in 2010. The company specializes in creating and commercializing oral drugs aimed at treating epilepsy and other central nervous system disorders. Its primary focus is on developing novel oral anticonvulsant agents designed to effectively reduce seizure frequency in patients with epilepsy. By providing safe and innovative treatment options, Tansna Therapeutics aims to enhance the quality of care for individuals suffering from these debilitating conditions.
Time to Cater
Angel Round in 2013
Time To Cater is a web-based platform that helps companies and individuals coordinate their ideal catered even at NO EXTRA COST to client. If you have had to coordinate catering for events or if you need food ordered quickly online, and especially if you have done it consistently, you understand that valuable time is wasted calling potential caterers for availability, prices, and delivery details, etc. We fix this problem by providing a web-based platform and mobile app that helps companies and individuals coordinate their ideal catered event. Our client only has to submit their event details and budget to our web application and then show up for the event and enjoy! We take care of EVERYTHING in between. And the BEST part is that there is NO EXTRA COST to our client for our service! We make money by making a commission from the caterers in our Preferred Caterer Network.
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