U.S. Department of Energy

Gross-Wen Technologies, Inc. develops, manufactures, and markets a wastewater treatment solution to recover nutrients from wastewater to municipalities and wastewater-producing industries. It offers revolving algal biofilm (RAB) system that recovers nitrogen and phosphorus from wastewater while producing algae biomass that could be sold as a fertilizer or bioplastic. The company was incorporated in 2013 and is based in Slater, Iowa.

LanzaJet producer of aviation fuel that captures waste gas emissions and uses bacteria to turn it into useable ethanol fuel.

Southern Research (SR) is an independent,nonprofit, scientific research organization with more than 400 scientists and engineers working across four divisions: Drug Discovery, Drug Development, Engineering, and Energy & Environment. SR supports the pharmaceutical, biotechnology, defense, aerospace, environmental, and energy industries as we work on behalf of the National Cancer Institute, National Institutes of Health, the U.S. Department of Defense, the U.S. Department of Energy, NASA, major aerospace firms, utility companies, and other private and government organizations.They pursue entrepreneurial and collaborative initiatives to develop and maintain a pipeline of intellectual property and innovative technologies that positively impact real-world problems.

NovoNutrients is focused on converting industrial waste carbon dioxide emissions into high-value protein ingredients for food and animal feed. The company has developed a fermentation platform that utilizes proprietary microbes and advanced gas fermentation systems to transform CO2, along with hydrogen and oxygen, into complete and safe single-cell protein. This innovative approach not only provides sustainable protein sources to support a growing population but also plays a role in combating climate change through carbon capture and utilization. By addressing both food security and environmental sustainability, NovoNutrients aims to meet the increasing demand for alternative protein solutions.

Lygos is a biotechnology company focused on providing sustainable solutions for renewable chemical production. Founded in 2011 and headquartered in Berkeley, California, Lygos engineers microbes to convert sugars into high-value industrial chemicals, emphasizing cost-effectiveness compared to traditional petrochemical processes. By utilizing advanced throughput screening and strain construction techniques, the company rapidly optimizes biological pathways to transform inexpensive and renewable feedstock into valuable chemical products. Lygos aims to replace persistent and often toxic chemicals with cleaner, more efficient alternatives, catering to business-to-business customers and fostering high-performing, sustainable solutions across the chemical industry.

Lygos is a biotechnology company focused on providing sustainable solutions for renewable chemical production. Founded in 2011 and headquartered in Berkeley, California, Lygos engineers microbes to convert sugars into high-value industrial chemicals, emphasizing cost-effectiveness compared to traditional petrochemical processes. By utilizing advanced throughput screening and strain construction techniques, the company rapidly optimizes biological pathways to transform inexpensive and renewable feedstock into valuable chemical products. Lygos aims to replace persistent and often toxic chemicals with cleaner, more efficient alternatives, catering to business-to-business customers and fostering high-performing, sustainable solutions across the chemical industry.

Manta Biofuel, LLC is a Maryland-based company that specializes in the production and distribution of renewable crude oil derived from algae. Established in 2014, Manta Biofuel aims to provide a cost-effective alternative to traditional fossil fuels, targeting the $10 billion heating oil market. The company has developed a patented technology involving a distributed magnetic harvesting system to efficiently extract algal biomass, which is then converted into renewable crude oil through a hydrothermal liquefaction process. This innovative approach not only offers a sustainable energy solution but also supports the long-term vision of transitioning the international shipping industry to carbon-neutral liquid fuels, contributing to broader efforts to decarbonize the economy.

Southern Research (SR) is an independent,nonprofit, scientific research organization with more than 400 scientists and engineers working across four divisions: Drug Discovery, Drug Development, Engineering, and Energy & Environment. SR supports the pharmaceutical, biotechnology, defense, aerospace, environmental, and energy industries as we work on behalf of the National Cancer Institute, National Institutes of Health, the U.S. Department of Defense, the U.S. Department of Energy, NASA, major aerospace firms, utility companies, and other private and government organizations.They pursue entrepreneurial and collaborative initiatives to develop and maintain a pipeline of intellectual property and innovative technologies that positively impact real-world problems.

Lumen Bioscience, Inc. is a biotechnology company focused on developing therapeutic biologics for oral delivery. It utilizes Spirulina, a blue-green algae, as an industrial-scale production platform for high-value molecules. The company engages in various services, including synthetic biology, protein design, immunology, bioreactor engineering, and cell physiology, catering to the food, cosmetics, and healthcare industries. Founded in 2017 and based in Seattle, Washington, Lumen Bioscience is advancing the development of topically and mucosally delivered biologic drugs aimed at treating and preventing common diseases.

Danforth Technology Company (DTC) is a venture builder based in St. Louis, Missouri, and operates as a subsidiary of the Donald Danforth Plant Science Center. Its primary role is to facilitate the early-stage development of startup companies that leverage technologies developed by the Center's scientists. DTC focuses on moving scientific discoveries into the marketplace more efficiently by providing intellectual property development, licensing, and entrepreneurship support. The company also offers seed funding and early management assistance to promising startups, enhancing the potential for innovation in plant science and contributing to broader societal goals such as improving human health and environmental sustainability.

As the world's population reaches 9.7 billion in the year 2050, global crop production will need to double to meet the projected demands for food, feed, fiber, and fuel. AFINGEN® develops novel biotechnology platforms for crops to grow faster and healthier and meet the natural resource demand in new sustainable manners.

Manta Biofuel, LLC is a Maryland-based company that specializes in the production and distribution of renewable crude oil derived from algae. Established in 2014, Manta Biofuel aims to provide a cost-effective alternative to traditional fossil fuels, targeting the $10 billion heating oil market. The company has developed a patented technology involving a distributed magnetic harvesting system to efficiently extract algal biomass, which is then converted into renewable crude oil through a hydrothermal liquefaction process. This innovative approach not only offers a sustainable energy solution but also supports the long-term vision of transitioning the international shipping industry to carbon-neutral liquid fuels, contributing to broader efforts to decarbonize the economy.

As the world's population reaches 9.7 billion in the year 2050, global crop production will need to double to meet the projected demands for food, feed, fiber, and fuel. AFINGEN® develops novel biotechnology platforms for crops to grow faster and healthier and meet the natural resource demand in new sustainable manners.

As the world's population reaches 9.7 billion in the year 2050, global crop production will need to double to meet the projected demands for food, feed, fiber, and fuel. AFINGEN® develops novel biotechnology platforms for crops to grow faster and healthier and meet the natural resource demand in new sustainable manners.

Manta Biofuel, LLC is a Maryland-based company that specializes in the production and distribution of renewable crude oil derived from algae. Established in 2014, Manta Biofuel aims to provide a cost-effective alternative to traditional fossil fuels, targeting the $10 billion heating oil market. The company has developed a patented technology involving a distributed magnetic harvesting system to efficiently extract algal biomass, which is then converted into renewable crude oil through a hydrothermal liquefaction process. This innovative approach not only offers a sustainable energy solution but also supports the long-term vision of transitioning the international shipping industry to carbon-neutral liquid fuels, contributing to broader efforts to decarbonize the economy.

Ecovia Renewables Inc., founded in 2014 as a spin-out from the University of Michigan and based in Ann Arbor, specializes in developing bio-based ingredients and materials through a proprietary fermentation process utilizing renewable biomass. The company offers a variety of products, including the EcoSynth platform for biochemical and biofuel production, a suite of biopolymers designed as biodegradable alternatives to traditional polymers, and cellulosic biofuels derived from lignocellulosic biomass. Ecovia's biopolymers are versatile, finding applications in agriculture, such as soil additives for water retention, and in personal care products, serving as thickeners and super-absorbent materials. The company is committed to sustainable practices, aiming to provide high-performing, cost-effective biobased solutions for various industries.

Genera Energy Inc. is a Tennessee-based company that specializes in providing biomass supply solutions for the biofuels, biopower, and biobased products industries. Established in 2008, it processes various biomass feedstocks, including switchgrass, corn stover, biomass sorghum, sugar cane bagasse, and wood. The company offers a comprehensive range of services, including energy crop production, turnkey supply-chain management, and consulting for biomass users and landowners. Genera Energy focuses on creating a connection between biomass users and landowners, ensuring that customers receive consistent, high-quality feedstock while landowners benefit from competitive returns and minimal risk.

Lygos is a biotechnology company focused on providing sustainable solutions for renewable chemical production. Founded in 2011 and headquartered in Berkeley, California, Lygos engineers microbes to convert sugars into high-value industrial chemicals, emphasizing cost-effectiveness compared to traditional petrochemical processes. By utilizing advanced throughput screening and strain construction techniques, the company rapidly optimizes biological pathways to transform inexpensive and renewable feedstock into valuable chemical products. Lygos aims to replace persistent and often toxic chemicals with cleaner, more efficient alternatives, catering to business-to-business customers and fostering high-performing, sustainable solutions across the chemical industry.

Symbios Technologies is commercializing its disruptive advanced low-cost aqueous plasma oxidation technology, the Symbios Tubular Plasma Reactor, to clean water, preserve the environment, and protect human health.

Arbsource is developing wastewater treatment systems for the food & beverage industry, cutting painfully expensive water and power bills with biotechnology.

Lygos is a biotechnology company focused on providing sustainable solutions for renewable chemical production. Founded in 2011 and headquartered in Berkeley, California, Lygos engineers microbes to convert sugars into high-value industrial chemicals, emphasizing cost-effectiveness compared to traditional petrochemical processes. By utilizing advanced throughput screening and strain construction techniques, the company rapidly optimizes biological pathways to transform inexpensive and renewable feedstock into valuable chemical products. Lygos aims to replace persistent and often toxic chemicals with cleaner, more efficient alternatives, catering to business-to-business customers and fostering high-performing, sustainable solutions across the chemical industry.

Yield10 Bioscience is an agricultural bioscience company dedicated to developing innovative technologies aimed at significantly improving crop yields in the United States and Canada. The company, which was founded in 1992 and is headquartered in Woburn, Massachusetts, operates its Trait Factory to create high-value seed traits for the agriculture and food sectors. Yield10 is particularly focused on optimizing carbon flow in plants, which allows for precise genetic alterations that enhance yields while minimizing the use of land, water, and fertilizers. Its research efforts are supported by collaborations with major agricultural firms to develop traits in crops such as soybean, potato, and forage sorghum. Additionally, Yield10 is advancing the oilseed Camelina sativa as a platform for producing sustainable seed products, including oils for renewable fuels and omega-3 fatty acids for various applications. The company's commitment to innovation is driven by the goal of enhancing global food security through its advanced genetic technologies.

Myriant Technologies is focused on manufacturing specialty chemicals from renewable feedstocks. They deliver products with a smaller environmental footprint.

ZeaChem is focused on developing sustainable alternatives to petroleum-based fuels and chemicals, utilizing renewable biomass sources such as wood chips, wheat straw, corn stover, and grasses. The company employs a proprietary fermentation process that converts all carbon in the sugars into end products, resulting in high yields and making its products competitive with traditional fossil fuels, even without subsidies. By targeting the $1 trillion chemicals and fuels markets, ZeaChem aims to provide high-margin solutions that address environmental concerns while maintaining economic viability.

Solazyme is a synthetic biology company that specializes in converting algal biomass into biofuels. Solazyme not only creates biofuels for the the transportation industry, but is experimenting with ways to tailor its products for the cosmetic and food industries.