Amboy Street Ventures

Gesynta Pharma AB is a clinical-stage pharmaceutical company based in Solna, Sweden, focused on developing innovative treatments for chronic inflammatory conditions through the inhibition of the pro-inflammatory enzyme microsomal prostaglandin E synthase-1 (mPGES-1). Originating from research at Karolinska Institutet, the company's most advanced drug candidate, vipoglanstat (GS-248), is being developed as a non-hormonal treatment for endometriosis, a prevalent and painful condition affecting many women of reproductive age. In preclinical studies, vipoglanstat has shown significant reductions in endometriotic lesions, pain relief, and improved well-being, with plans for a clinical phase II study underway. Additionally, Gesynta Pharma is preparing to advance another drug candidate, GS-073, into clinical phase I for a different inflammatory condition in 2023. The company aims to provide safe and effective treatment options for patients facing serious diseases related to chronic inflammation. Founded in 2017, Gesynta Pharma is supported by various investors, including Hadean Ventures, Industrifonden, and Linc.

Testmate Health is a medtech startup and an award-winning spin-off of the University of Geneva, focused on developing innovative healthcare solutions. The company has created a smartphone-compatible test kit that can diagnose diseases with identifiable DNA or RNA sequences, providing results directly at home in just minutes. Its first product is a rapid urine self-test for the four most common sexually transmitted diseases, addressing the urgent need for timely diagnosis, as one million new STDs are diagnosed daily. Traditional testing often requires lab work and can take up to seven days for results. Testmate Health's all-in-one kit is designed for ease of use, allowing users to obtain immediate results that can be scanned by a smartphone for quick access to treatment if necessary. The company is also working on additional test kits for other diseases, aiming to empower individuals to manage their health conveniently from home.

Granata Bio is a biotechnology company established in 2018, dedicated to identifying and developing therapeutics for fertility patients. The company focuses on creating a comprehensive portfolio of fertility treatments and possesses expertise in commercialization, late-stage clinical trials, and regulatory development. Granata Bio aims to address significant challenges faced by medical professionals in the field of fertility treatment. Recently, the company announced a collaboration with IBSA Institut Biochimique to co-develop a novel subcutaneous progesterone solution, further enhancing its commitment to advancing fertility care.

Evvy is a company focused on improving female health by offering at-home vaginal microbiome tests. These tests utilize metagenomic sequencing to analyze symptoms and identify risks associated with important health issues. By providing personalized reports, Evvy aims to empower women with insights about their bodies, thereby addressing the gender health gap and enhancing overall health outcomes for women.

HERmd is a healthcare provider specializing in comprehensive health, beauty, and wellness services tailored specifically for women. Founded by Somi Javaid in 2019 and headquartered in Cincinnati, Ohio, the company offers a broad range of services designed to empower women and address their unique needs. These services include gynecology, menopause management, sexual medicine, obesity counseling, labiaplasty, and various medical aesthetic treatments such as clinical facials and chemical peels. HERmd aims to create a safe and trusted environment for women to discuss and manage their health and well-being, regardless of how personal the issues may be.

Contraline, Inc. is a biotechnology company based in Charlottesville, Virginia, focused on developing male birth control solutions. The company is creating an innovative, long-lasting, non-hormonal, and reversible contraceptive known as Echo-V. This product consists of an ultrasound-visible polymer solution that is injected into the vas deferens, forming a polymer hydrogel device. This device acts as a semi-permeable membrane, effectively blocking sperm while allowing bodily fluids to pass through. Contraline also offers Vasintomy, a non-surgical procedure for the insertion of Echo-V, providing a cost-effective and user-friendly approach to male contraception. Founded in 2015, Contraline aims to transform male reproductive health through its groundbreaking technology.

Hey Jane is a telehealth startup that connects patients to healthcare providers that offer online medical consultations. The company's innovative Complete Care model utilizes technology for unparalleled layers of support: medical, emotional, and social. Since 2021, Hey Jane has helped nearly 20,000 patients get the care they need. And this is only the beginning; soon, we will reimagine care for even more common but underserved treatments, with the ultimate goal of becoming the most trusted healthcare company out there—one that pushes the boundaries of access with convenient, inclusive, and patient-driven care.

Dame Products is a sexual wellness brand focused on creating well-engineered sex toys that enhance intimacy and empower women's sexual experiences. The company designs strap-free, non-intrusive vibrators tailored to meet diverse sexual needs, allowing users to integrate these products seamlessly into their sex lives. By prioritizing a consumer-centric approach, Dame Products engages with women and sex therapists to inform their designs, ensuring that their offerings address the complexities of female sexuality.

Aunt Flow Corp. is a manufacturer and supplier of menstrual products, focusing on providing access to high-quality hygiene items for individuals who menstruate. Founded in 2018 and based in Columbus, Ohio, the company offers a range of products, including tampons and pads made from 100% organic cotton, as well as additional merchandise such as clothing and accessories. Aunt Flow emphasizes sustainability by producing biodegradable products and operates a unique model where for every tampon purchased, a tampon is donated to someone in need within the United States. The company sells its products directly to consumers online and partners with businesses and schools to make menstrual products available at no charge through free-vend dispensers, ensuring that all individuals have access to essential hygiene products.

Dipsea is an audio storytelling platform based in San Francisco, California, that focuses on women's entertainment and sexual wellness. Founded in 2018, the company produces original content in the form of short, immersive audio stories designed to empower women to explore their sexuality in a comfortable and imaginative way. Dipsea's subscription-based application offers a unique collection of non-narrative guided audio stories, allowing listeners to access auditory erotica at their convenience. Through its innovative approach, Dipsea aims to enhance the experience of intimacy and self-discovery for its audience.

Dame Products is a sexual wellness brand focused on creating well-engineered sex toys that enhance intimacy and empower women's sexual experiences. The company designs strap-free, non-intrusive vibrators tailored to meet diverse sexual needs, allowing users to integrate these products seamlessly into their sex lives. By prioritizing a consumer-centric approach, Dame Products engages with women and sex therapists to inform their designs, ensuring that their offerings address the complexities of female sexuality.

Gennev is a digital health company based in Seattle, Washington, that focuses on women's health, particularly during midlife and menopause. Founded in 2015, Gennev aims to empower women by providing accessible information, healthcare providers, and community support for managing hormone-driven symptoms such as hot flashes, insomnia, anxiety, and loss of libido. The company employs an integrated care model that offers personalized and comprehensive treatment options through telehealth appointments, allowing women to address menopause-related challenges effectively and proactively.