Avation Medical
Series C in 2024
Avation Medical, Inc. is a company focused on developing a non-invasive closed-loop neuromodulation system aimed at treating overactive bladder in a home setting. Incorporated in 2016 and based in Columbus, Ohio, Avation Medical is at the forefront of innovation in wearable nerve stimulation systems. The company emphasizes empowering patients to manage their therapies, facilitating a more personalized approach to care. By leveraging advanced technologies, Avation Medical seeks to transform the neuromodulation market, enhancing the quality of care for individuals with chronic conditions through patient-centric solutions.
Clarametyx Biosciences
Series A in 2024
Clarametyx Biosciences, Inc. is a biotechnology company founded in 2020 and headquartered in Columbus, Ohio. The company focuses on developing targeted and immune-enabling biologic therapies that address persistent infections associated with biofilms, which are protective layers that shield bacteria and complicate treatment. Clarametyx has created a novel technology platform that allows for the targeting of these biofilms, thereby enhancing immune response and facilitating antibiotic intervention. One of its key products in development is CMTX-001, a humanized monoclonal antibody currently in the late preclinical stage, aimed at treating hospital-acquired pneumonia. Clarametyx Biosciences is dedicated to combating life-threatening infections and reducing antibiotic resistance through its innovative therapeutic solutions.
Society Brands
Grant in 2023
Society Brands is a consumer products company established in 2020. Headquartered in Canton, Ohio, it acquires e-commerce native brands that primarily sell on Amazon and their own direct-to-consumer sites. The company aims to enhance the shopping experience for everyday products by integrating various brand offerings, focusing on e-commerce efficiency and customer engagement.
Lentechs
Venture Round in 2023
Lentechs is a medical device company based in Columbus, Ohio, specializing in the development of innovative soft bifocal contact lenses. The company focuses on creating a new generation of soft, suspended progressive contact lenses that enhance user experience by allowing natural eye movement, similar to that achieved with traditional bifocal glasses. This design aims to provide improved comfort and visual clarity, enabling users to see freely without discomfort. Lentechs is dedicated to addressing the needs of patients throughout their lifecycle, ensuring that its products offer both functionality and ease of use.
Enspire DBS Therapy
Series B in 2023
Enspire DBS Therapy focuses on restoring motor function for stroke survivors through proprietary deep brain stimulation (DBS) therapy combined with physical rehabilitation. It aims to accelerate post-stroke recovery by mediating the effects of stimulation and rehabilitation.
Invirsa develops therapeutic agents that enhance immunity and promote healing. Its lead compound, INV-102, reduces cellular injury caused by infections like adenovirus, stimulates immune response, and accelerates wound repair. Invirsa focuses on treating conditions such as keratoconjunctivitis and upper respiratory tract infections.
MediView
Venture Round in 2023
MediView, LLC is a medical device company based in Cleveland, Ohio, that specializes in developing augmented reality surgical navigation systems aimed at enhancing surgical processes for healthcare providers. Founded in 2017, the company focuses on creating advanced technologies for surgical navigation, particularly for the ablation and biopsy of cancerous tumors. MediView's flagship product, MediView, utilizes real-time, fused-holographic visualization to enable surgeons to navigate procedures with greater accuracy and efficacy. This innovative approach allows for enhanced examination of patients through augmented reality 3D visualization, facilitating improved surgical outcomes and supporting remote collaboration among healthcare professionals.
Genetesis
Series C in 2022
Genetesis LLC, established in 2013 and based in Mason, Ohio, specializes in designing, developing, and providing biomagnetic imaging solutions for cardiac healthcare. The company's primary product is Genetesis CardioFlux, a mapping system that optimizes the detection, characterization, and treatment of cardiac rhythm disorders by visualizing electrical currents of the heart in 3D. Additionally, they offer Faraday Analytical Cloud, a HIPAA-compliant platform managing end-to-end data workflow for their Magnetocardiograph (MCG). Genetesis aims to redefine clinical diagnosis, monitoring, and screening processes for patients at risk of myocardial ischemia and coronary artery disease, using non-invasive, radiation-free methods.
Centerline Biomedical
Series B in 2022
Centerline Biomedical, Inc. is a Cleveland, Ohio-based company founded in 2014 that specializes in developing advanced surgical navigation technologies. The company focuses on an Intra-Operative Positioning System, which utilizes non-x-ray based three-dimensional GPS technology to enhance the precision of endovascular procedures and minimize radiation exposure for both patients and medical staff. Centerline's innovative system aids surgeons in navigating complex three-dimensional vascular anatomy, thereby improving surgical outcomes in interventional vascular procedures. The technology is rooted in advancements made at the Cleveland Clinic, reflecting a commitment to enhancing the safety and effectiveness of minimally invasive surgeries.
Prevedere
Venture Round in 2022
Prevedere is a predictive analytics company based in Columbus, Ohio, with an additional office in Sunnyvale, California. Founded in 2012, the company specializes in developing business performance forecasting software that helps leaders make informed decisions by providing real-time insights into future business performance. Prevedere's platform tracks and manages economic, environmental, and consumer behavior data to identify leading indicators for company revenues, profits, and individual products. The company offers a range of solutions, including predictive marketing analytics, financial forecasting intelligence, demand planning, and sales planning. Additionally, Prevedere provides industry outlook reports, Chinese consumer behavior data, and predictive insights, along with economic consulting, data science, and training services.
Eikonoklastes Therapeutics
Series A in 2021
Eikonoklastes Therapeutics is a biopharmaceutical company based in Cincinnati, Ohio, founded in 2019. The company focuses on developing innovative immunotherapies for severe diseases with high unmet clinical needs. Their pipeline includes two primary assets: ET-101, a gene therapy engineered to overexpress Caveolin-1 for treating neurodegenerative diseases, and ET-201, a tissue factor therapy targeting solid tumor cells, tumor vasculature, and tumor stem cells to inhibit tumor growth and recurrence. Eikonoklastes aims to rapidly advance these therapies from preclinical stages to clinical proof-of-concept and approval through relatively small clinical trials.
DAtAnchor
Convertible Note in 2021
Traditional IT controls focus on locking down networks, devices, and people. All of this is done in the name of protecting data. But, once files are moved, shared, or stolen, the data is no longer protected. Even worse, these controls get in the way and frustrate business users to the point they intentionally work around them. Anchor inverts the equation by baking protection into the data, invisible to the business users (like antivirus), so that files are free to travel and security is out of the way. Simply put, wherever the data goes, it is protected.
Anchor is a SaaS platform, with an endpoint component, that bakes protection into your files with a unique transparent combination of encryption, continuous multi-factor access controls, and a digital chain of custody. And when you do share or collaborate, Anchor protection stays with your data, even when it leaves your organization. Anchor empowers you to maintain control of your files while collaborating on premise or in the cloud, including forensic logging and revoking access.
In under 90 minutes, Anchor is fully deployed and empowers your business users to securely work and collaborate without complicated security products or rules in the way. All without requiring you to change existing IT controls or how your users and applications work today.
DAtAnchor is a result of a multi-year research activity, developed at Ohio State University. The development team currently has 6 members, 4 of which are full-time. We have seed level funding for >1M and an advisory board with members at the senior vice president level in Fortune 500 companies.
S4 Medical
Series A in 2021
Founded in 2017, S4 Medical specializes in developing medical devices for cardiac procedures. Its flagship product is a device designed to protect the esophagus during catheter ablation treatments for atrial fibrillation.
Ohio Valley Bank
Grant in 2019
Ohio Valley Bank is a full-service financial institution serving Southeastern Ohio and western West Virginia. It provides a broad range of commercial and consumer banking services, including digital banking, home loan services, and trust services, along with deposit products such as checking, savings, time and money market accounts. The bank offers personal, commercial, student, construction and real estate loans, loan servicing, individual retirement accounts, safe deposit boxes, and wire transfers.
Ahalogy is a digital marketing company that operates as the Passion to Purchase Platform, focusing on helping brands and agencies connect with consumers through their interests. The company provides a range of services, including category trend data, authentic influencer content, and social optimization technology, which enable clients to enhance user engagement and drive sales. As an official Pinterest Marketing Partner, Ahalogy collaborates with leading social networks to deliver effective marketing solutions. Headquartered in Cincinnati, Ohio, Ahalogy also has offices in New York, Chicago, Los Angeles, and San Francisco, positioning itself in key markets for brand marketing. Through its innovative platform, Ahalogy aims to provide proven return on investment for its clients by leveraging data-driven insights and creative content strategies.