i2E is a not-for-profit venture development organization based in Oklahoma City, Oklahoma, founded in 1997. It focuses on investing in technology-based entrepreneurs and companies within the software, healthcare, and information technology sectors. As a key component of Oklahoma’s Innovation Model, i2E receives support from the Oklahoma Center for the Advancement of Science and Technology. The organization manages over $47 million in assets through its for-profit venture capital fund subsidiaries, aiming to foster innovation and entrepreneurship in the region.

Echo Investment Capital is a strategic investor founded in 2010, focusing on innovative companies across various industries such as life sciences, technology, media, education, and real estate.

Cortado Ventures is a venture capital firm based in Oklahoma City, founded in 2020. The firm invests in capital-efficient, technology-led B2B companies across insurtech, biotech, fintech, energy tech, aerospace, and agtech, with a geographic focus on Oklahoma. It operates as a registered investment adviser, providing oversight and guidance to its portfolio.

Founded in 2020 and based in Tulsa, Oklahoma, Atento Capital is a venture capital firm focused on investing in early-stage technology companies. The firm seeks exceptional entrepreneurs addressing large markets and aims to drive outsized returns while fostering job creation and supporting local tech ecosystems.

Founded in 2019, Plains Ventures is an early-stage venture capital firm based in Oklahoma City, Oklahoma. It specializes in uncovering and investing in groundbreaking ideas and entrepreneurs at the Seed and Series A stages between the coasts.

HPS Investment Partners is a global investment firm focused on non-investment grade credit. Founded in 2007 and headquartered in New York, it operates with offices worldwide. The firm originated as a unit of Highbridge Capital Management, a subsidiary of J.P. Morgan Asset Management, and was acquired by its principals in 2016, with J.P. Morgan retaining the hedge fund strategies. HPS manages a broad set of capital-structure strategies, including syndicated leveraged loans, high-yield bonds, privately negotiated senior secured debt, mezzanine financing, asset-based leasing, and private equity, serving clients across industries such as insurance, healthcare, media, retail, logistics, and marine.

Established in 2019 and headquartered in Tulsa, Oklahoma, FortySix Venture Capital is an early-stage investment firm focusing on technology sectors.

Trailblazer Capital is a venture capital firm based in Dallas, Texas, that focuses on investing in seed/start-ups, early-stage companies, and growth capital. The firm primarily targets sectors such as networking and telecommunications, wireless and mobility services, software applications, database management, and enterprise software, with interests in security, cloud computing, e-commerce, and digital media. Established in 2006, Trailblazer Capital typically invests between $0.1 million and $5 million in companies, predominantly those located in Texas and Oklahoma. The firm deliberately avoids investments in life sciences, biotechnology, medical devices, real estate, and natural resources.

Founded in 2022, Serac Ventures is a seed-stage venture capital firm based in Oklahoma City, Oklahoma. It invests in early-stage companies focusing on financial technology, business-to-business software-as-a-service, and future of work sectors.

Established in 2022 and headquartered in Tulsa, Oklahoma, EIC Rose Rock is a venture capital firm focusing on early-stage investments within the energy sector.

Founded in 2018, Cameron Ventures is a venture capital firm based in Oklahoma City, Oklahoma. The firm focuses on investing in early-stage companies (Pre-seed to Series A) within the InsurTech, FinTech, and Enterprise Applications sectors.

Oklahoma Life Science Fund is a Tulsa-based venture capital firm focusing on health care and life sciences opportunities across Oklahoma. The firm invests in therapeutics, medical devices, diagnostics, biotechnology, and tech-enabled services, primarily supporting Oklahoma-based startups. Through its funds, including early-stage vehicles like Oklahoma Life Science Fund III, it has built a portfolio of companies that have created jobs and attracted regional and national venture capital. The firm aims to accelerate growth in Oklahoma's life sciences ecosystem by providing capital and strategic support to early-stage ventures.

Startup Capital Ventures, L.P. is a venture capital firm specializing in investments in early stage and growth capital companies. The firm seeks to invest in B2B technology companies with a focus on security, fintech, travel, wireless, cloud, SaaS, healthcare information technology, and internet of things. It primarily invests in Silicon Valley, Hawaii, Texas, Oklahoma and China. The firm typically makes an initial investment between $0.25 million and $1 million in its portfolio companies, with reserves for future funding rounds. It typically co-invests with other leading funds at the Series Seed and Series A rounds. Startup Capital Ventures is based in Menlo Park, California with additional offices in Honolulu, Hawaii, Quarry Bay, Hong Kong and Shenzhen, China.

Startup Capital Ventures is a venture capital firm that backs early-stage enterprise technology companies. Based in Menlo Park, California, and Honolulu, Hawaii, it concentrates on capital-efficient software and B2B tech firms that generate revenue and show potential for near-term profitability. The firm emphasizes strong management teams and builds supportive relationships through flexibility, integrity, and patience, aided by an extensive network of strategic contacts that help portfolio companies reach critical milestones. It pursues investments in the United States and China, with a focus on software, fintech, healthtech, internet of things, SaaS, and other B2B sectors. The team combines hands-on operating experience with a collaborative approach to add value beyond capital. Geographic activity centers on Silicon Valley and adjacent markets, including Hawaii, Texas, and Oklahoma.

Draper Associates is an early-stage venture capital firm investing globally in innovative teams building transformative companies across industries such as new media, gaming, SaaS, cloud, fintech, IoT, and mobile. Founded in 1985, the firm encourages entrepreneurs to drive business growth, create jobs, and generate wealth through disruptive technologies.

Russell Westbrook Enterprises is a company dedicated to supporting global communities through strategic investments and partnerships. It focuses on providing financial and investment management services aimed at inspiring and uplifting communities worldwide. By leveraging both economic and social capital, the company engages in ventures that positively impact businesses and communities. Through a combination of endorsements, equity stakes, and potential investments, Russell Westbrook Enterprises facilitates connections within the business landscape, promoting economic development. The firm aims to help corporations enhance brand awareness and differentiate themselves in the marketplace while exploring new opportunities for its portfolio companies.

Germin8 Ventures is a venture capital firm investing in disruptive Food & AgTech companies globally. Established in 2017, it focuses on transformative technologies and solutions across the agriculture and food value chain.

Mercury is a purpose-built early-stage venture capital platform dedicated to supporting transformative software startups in communities across America, particularly in Middle America. The company identifies and partners with exceptional founders, offering both guidance to new entrepreneurs and resources to experienced innovators. With a focus on operationally-driven investment strategies, Mercury has generated over $9 billion in value, facilitating rapid and sustainable growth for its portfolio companies. Through its comprehensive growth partner network, Mercury aims to leverage local assets and talent, fostering entrepreneurship and innovation within the regions it serves.

EnCap Investments L.P., established in 1988, is a Houston, Texas-based private equity firm focused on the oil and gas industry. It specializes in seed, start-up, emerging growth, and early venture investments, typically allocating between $10 million and $350 million per deal. The firm primarily invests in upstream and midstream oil and gas companies, with a particular interest in natural gas pipelines, processing facilities, and energy infrastructure projects. EnCap also considers investments in the energy transition sector. It operates from offices in Houston and Dallas, Texas.

Ulu Ventures is a Palo Alto, California-based seed and early-stage venture capital firm that backs technology-driven startups across the United States. Founded in 2008, it focuses on internet-enabled consumer and business services and a broad range of sectors including EdTech, FinTech, healthcare, sustainability, enterprise IT, SaaS, IoT, digital media, mobile, agtech, and marketplaces. The firm emphasizes backing diverse entrepreneurial teams and typically engages in co-investments with other investors to pursue meaningful exits. It is described as the first Latina-led venture fund in Silicon Valley and is among the larger seed-focused vehicles in the region.

Advantage Capital Partners is a United States‑based venture capital firm that provides growth equity, debt, and mezzanine financing to small and mid‑market companies, with a focus on underserved communities and state and local economic development. The firm invests across sectors including manufacturing, technology, business services, life sciences, and energy, and also supports real estate development projects with equity and debt. It typically makes initial investments ranging roughly from half a million to ten million in companies with modest sales, and may participate in larger follow‑on rounds or co‑invest with other firms. It uses senior debt, mezzanine debt, subordinated loans, and government‑guaranteed lending, and often pursues equity positions through preferred shares or convertible notes. Advantage Capital operates nationwide in the United States, with roots in New Orleans and offices in multiple states, and has backed thousands of jobs and housing projects as part of its mission to expand inclusive economic growth.

Optum is a healthcare services and innovation company dedicated to improving health outcomes. It offers a range of services including family medicine, mental health care, and specialized therapies for rare diseases. Optum also provides healthcare financial services and technology solutions to health plan providers.

1789 Capital is a growth equity firm based in Palm Beach, Florida, founded in 2023. It provides venture and growth capital to middle, late, and crossover-stage companies across sectors such as artificial intelligence, software, aerospace and defense, healthtech, and fintech. The firm pursues investments aligned with its thematic focus on the replication or parallel economy, deglobalization, and sectors deemed anti-ESG, alongside funding cutting-edge technologies that disrupt industries burdened by bureaucracy.

Founded by Stephen Hays, a West Point graduate and former investment banker in aerospace & defense, What If Ventures invests in disruptive healthcare and defense industrial startups. With nearly $100 million deployed across over 80 companies since 2019, the firm focuses on these sectors due to their large addressable markets, complex regulations, significant government customers, and lack of successful innovation by new entrants.

Hard Yaka is an investment firm based in Crystal Bay, Nevada, founded in 2010. It pursues technology investments across private equity and venture capital, including buyouts and distressed opportunities, and it frequently seeks majority stakes. The firm focuses on digital transformation infrastructure, including portable identity, payments, marketplaces, and regtech, and also backs early-stage opportunities in exchange space startups, targeting verticals within exchange markets as well as horizontals such as messaging and payments across exchange sectors.

UNC Kenan-Flagler Private Equity Fund is a student-run private equity and venture capital firm located in Chapel Hill, North Carolina, established in 2007. The fund focuses on making investments in both early and late-stage companies, engaging in buyouts, growth capital, and mezzanine debt financings. It aims to invest between $0.1 million and $0.15 million in portfolio companies that typically have enterprise values ranging from $20 million to $125 million. The fund operates with the dual purpose of delivering real returns for investors while providing an educational experience for its student members. It collaborates with partner private investment firms to enhance its investment strategies and reach.

Founded in 1999, OCA Ventures is a Chicago-based venture capital firm focusing on early-stage investments primarily in technology and highly-scalable services businesses. The firm's investment focus areas include digital health, fintech, consumer software, and enterprise software.

L2Capital is a venture capital and private equity firm that offers investment advisory and portfolio management services.

Founded in 2019, Uncorrelated Ventures is a venture capital firm based in San Francisco. It focuses on investing in early-stage infrastructure software companies.

Founded in 2021, Yellow Rocks! is a venture capital firm investing in early-stage companies with global expansion potential. They focus on disruptive technologies and aim for startups to reach $1 billion valuation. With a team distributed across the USA, Portugal, and Armenia, they leverage their collective experience from organizations like World Bank, IFC, Google, EPAM, MIT, Harvard, Stanford, Y Combinator, TechStars, MassChallenge, and 500 Startups.

Founded in 2017, Stout Street Capital is a Denver-based venture capital firm investing in early-stage technology companies. They focus on sectors such as software, fintech, advanced materials, robotics, and artificial intelligence, with an emphasis on underserved markets, particularly the Rocky Mountain region.

Founded in 1863, Mayo Clinic is a non-profit organization based in Minnesota, United States. It provides comprehensive medical care services across various specialties, conducts extensive research, and offers education in clinical medicine.

Cottonwood Capital Partners is a venture capital firm that backs early- and seed-stage startups in disruptive technology and related fields such as healthcare, information technology, nanotechnology, photonics, advanced materials, sensors, clean energy, robotics, life sciences, and enterprise software. The firm focuses on Southwest United States and Northern Europe, investing primarily in Arizona, New Mexico, Texas, Colorado, and Utah, and in the Netherlands and parts of Northern Europe, including Mexico as part of its regional reach. Typical investments range from about $1 million to $3 million, and the firm often takes a board seat on portfolio companies. Founded in 2009, Cottonwood Capital Partners is based in Los Alamos, New Mexico, with additional offices in El Paso, Santa Fe, and Enschede, Netherlands.

Founded by Darcy Howe in 2016, KCRise Fund is a venture capital firm based in Kansas City, Missouri. It invests alongside other institutional investors in early-stage companies located in Kansas and the western half of Missouri. The fund focuses on sectors such as software, TMT, B2B products/services, energy, financial services, healthcare, and information technology.

Lightship Capital is a venture capital firm focused on investing in early-stage startups, particularly those led by underrepresented minorities and located outside of major tech hubs like Silicon Valley, New York City, and Boston. The company concentrates its investments in sectors such as artificial intelligence, consumer packaged goods, sustainability, e-commerce, healthcare, and real estate.

Established in 2022 and headquartered in Los Altos, California, Stellar Ventures is a venture capital firm led by women. It focuses on investing in innovative space technology companies.

Greenspring Associates, established in 2000, is a global investment firm headquartered in the United States. It specializes in fund of funds management, offering commingled funds and customized partnership solutions to a diverse range of international clients. The firm invests in established and emerging venture capital fund managers, early and growth-stage venture-backed companies, and secondary venture capital fund and direct investments. With over $7.3 billion in committed capital, Greenspring's dedicated team combines extensive expertise in both venture fund and direct investments.

New Enterprise Associates is a venture capital firm founded in 1977 and based in Menlo Park, California, with offices in the United States, India and China. It makes investments across technology and healthcare startups at multiple stages, from seed to growth, including software, cloud, data, internet services, fintech, AI, e-commerce, and enterprise technology, as well as healthcare information technology, life sciences, medical devices, and biopharma. It also considers energy technology and infrastructure opportunities, such as solar, batteries and smart grids. The firm pursues a global approach, with activity in the United States, Asia and other regions, and supports companies through rounds of financing ranging from small to sizable investments as they scale. NEA focuses on building portfolios in software, IT services, consumer technology, and healthcare technology, backing ambitious entrepreneurs across sectors and geographies.

Battery Ventures is a technology-focused investment firm founded in 1983 and based in Boston, Massachusetts. It engages in venture capital and private equity investments in technology companies, with emphasis on software (including application and infrastructure software), IT infrastructure technologies, consumer internet and mobile services, industrial technologies, and life science tools. The firm seeks to back category-defining businesses with potential for scalable growth, often supporting companies through multiple stages and across select global regions.

Victorum Capital is an angel network based in Oklahoma City, founded in 2019. The organization brings together a network of investors, entrepreneurs, and partners dedicated to identifying, funding, and supporting promising business opportunities in the region. Through collaboration and strategic partnerships, Victorum Capital aims to foster innovation and growth within the local entrepreneurial ecosystem.

Cubit Capital is a venture capital and private equity firm headquartered in Dallas, Texas, founded in 2022. The firm focuses on investing in a diverse range of companies across various sectors, seeking to support innovative businesses with growth potential. By leveraging strategic insights and industry expertise, Cubit Capital aims to foster the development of its portfolio companies, contributing to their success in the competitive market.

Decisive Point is a New York-based venture capital firm that backs technology companies serving government, public safety, and defense. Founded in 2018, it targets investments across technology, defense, energy, security, health, and infrastructure, with a focus on founders who pursue solutions to national challenges. The firm helps portfolio companies navigate the federal market and scale products for both government and commercial customers, connecting teams with potential customers, partners, and policymakers to accelerate development and deployment of innovative technologies that address public needs.

Alumni Ventures Group is a venture capital firm based in Manchester, New Hampshire, with offices across North America. It provides access to venture investing for individual accredited investors, particularly alumni networks, by offering diversified portfolios of venture opportunities and allowing members to invest alongside fellow alumni in ventures led by peers. The firm backs early-stage and later-stage opportunities across technology, consumer, healthcare, financial services, and other sectors, with a sector- and geography-agnostic approach. It typically invests between $10,000 and $3 million per deal and emphasizes the involvement of alumni connections and an institutional lead investor in opportunities. Alumni Ventures also offers focused funds to broaden participation, enabling accredited investors to access venture portfolios diversified by type, sector, stage, and geography. The model aims to democratize access to venture capital while maintaining rigorous selection standards through alumni networks.

Founded in 2006, Greycroft is a venture capital firm based in New York and Los Angeles. With over $1 billion under management, it focuses on early-stage investments in consumer internet, financial technology, healthcare, and enterprise software sectors across the United States. The firm leverages its extensive network of media and technology industry connections to help entrepreneurs gain visibility, build strategic relationships, and bring products to market.

Founded in 2018, Town Hall Ventures is a New York-based investment firm dedicated to transforming the U.S. healthcare market through technology. It invests in and supports visionary entrepreneurs focused on improving care delivery and health outcomes for underserved populations.

Wind Point Advisors, LLC is a private equity and venture capital firm specializing in leveraged buyouts, recapitalizations, industry consolidations, growth capital, and expansion capital investments in middle market companies. It also seeks to invest in corporate divestitures or family-held businesses and seek add-on acquisitions. The firm does not seek to invest in companies in real estate, retail or restaurants sectors. It prefers to invest in business services, packaging, consumer products, healthcare, transportation, logistics and route-based businesses, media and communications, food and tobacco products, and industrial products sectors based in the United States. The firm seeks to invest between $15 million and $150 million in companies with revenues between $50 million and $300 million, enterprise values between $100 million and $500 million, and a minimum EBITDA of $8 million. It prefers to take a majority stake. It is typically the control investor in each of its portfolio companies. Wind Point Partners was founded in 1984 and is based in Chicago, Illinois.

White Star Capital is a global multi-stage technology investment firm and venture platform headquartered in New York, with a presence across North America, Europe and Asia. It backs exceptional entrepreneurs building ambitious, internationally scalable tech companies, helping portfolio founders scale their businesses from Series A onwards through its experience, networks and value-add support. The firm invests across software, information technology and digital assets, operating a core venture program and a dedicated digital asset strategy that backs crypto networks and blockchain-enabled businesses. Its offices span New York, London, Montreal, Toronto, Paris, Tokyo and Hong Kong, enabling it to partner with founders to expand internationally.

Energy Spectrum Capital is a Dallas-based private equity and venture capital firm focused on energy infrastructure investments in North America. It specializes in midstream energy assets such as oil and gas pipelines, storage and transportation facilities, crude and natural gas pipelines, natural gas liquids, and related infrastructure, as well as energy service and power development companies. The firm typically makes equity investments of 50 to 200 million, including follow-on rounds, and targets exits after roughly three to seven years. Founded in 1995, it concentrates on opportunities in the United States and Canada.

HG Ventures is the venture capital arm of The Heritage Group, headquartered in Indianapolis, Indiana. It funds and partners with early-stage and growth-stage companies developing advanced materials and systems for transportation, infrastructure, environmental services, and specialty chemicals, including digital solutions relevant to these industries. The firm emphasizes United States opportunities and leverages The Heritage Group's operating companies and research center to provide portfolio companies with industry expertise, commercial networks, and technical capabilities. HG Ventures pursues a value-add approach by supporting companies through strategic collaboration and scaling their technologies, often investing in collaborations that align with the Heritage Group's core businesses.

Elevate Capital is a venture capital firm based in Hillsboro, Oregon, established in 2016. It focuses on seed and early-stage investments across the United States, with a regional emphasis on the Pacific Northwest and Portland metro area. The firm targets technology-enabled startups and seeks to diversify founder representation, supporting ventures founded by underrepresented entrepreneurs. Elevate Capital typically participates in early rounds and makes minority investments, providing more than capital through advisory support and access to networks to aid long-term growth. Portfolio scope includes software, life sciences, hardware, consumer products, fintech, healthcare, sustainability, and related technology sectors.