Connecticut Innovations is a venture capital organization based in New Haven, Connecticut. Founded in 1989, it provides strategic capital and operational insight to innovative companies across Connecticut, with investments spanning seed to later stages in sectors including software as a service, manufacturing, life sciences, clean tech, oncology, cybersecurity, infrastructure, big data, e-commerce, and technology driven industries such as energy, information technology, and photonics. The organization supports portfolio companies through flexible financing, strategic guidance, and introductions to partners and resources within the Connecticut ecosystem.

Elm Street Ventures is a New Haven, Connecticut-based venture capital firm that concentrates on seed and early-stage investments in life sciences, healthcare, and related technology. It typically backs companies founded on intellectual property from Yale University and regional research institutions, with a focus on therapeutics, medical devices, diagnostics, laboratory tools, materials, and healthcare services, as well as software, clean technology, and information technology. The firm seeks opportunities near New Haven but is not limited to it, and provides more than capital, including strategic guidance and operational support through experienced partners who may take interim CEO or operating chair roles. Initial investments range from several hundred thousand dollars to over a million, with potential for follow-ons. Elm Street Ventures emphasizes attractive markets, strong patent protection, defensible market position, and a world-class management team.

LaunchCapital is a venture capital firm based in New Haven, Connecticut, that funds seed and early-stage startups. It focuses on technology, consumer, and medical sectors and targets commerce, marketplaces, media and entertainment, enterprise software and services, data, finance, healthcare, and emerging technologies. The firm maintains offices in Boston, New York, New Haven, and San Francisco and pursues opportunities for exponential growth by providing equity investments and other capital support to startups in the initial development stage. By helping founders scale from concept to revenue, LaunchCapital aims to optimize early-stage capital structures and support sustainable growth for portfolio companies.

Axiom Venture Partners is a venture capital firm based in East Hartford, Connecticut, that provides funding to technology and biotechnology companies across the United States. It engages with startups and growth companies at various stages, with a focus on mid- to late-stage opportunities, and concentrates on sectors such as communications, software, internet infrastructure, information technology, and related high-technology fields.

Fairview Capital Partners is an independent investment management firm focused on fund-of-funds in the private markets. Founded in 1994, it is headquartered in West Hartford, Connecticut, with an office in San Francisco. The firm specializes in venture capital, diverse and emerging managers, and direct co-investments, and serves institutional clients such as foundations, endowments, pension plans, and family offices. It manages the Fairview family of venture capital and private equity funds-of-funds and is minority-owned, reflecting its inclusive approach to leadership and investing. Since inception, the firm has overseen aggregate fund capitalization exceeding ten billion dollars.

Cava Capital is a venture capital firm based in Connecticut that pursues early-stage growth opportunities in consumer-focused technology sectors. It concentrates on Mobile, Commerce, Software as a Service, Marketplaces and Digital Marketing, with themes including the rise of the consumer economy, the millennial generation, the shared economy, and the interplay of brand and technology in building sustainable companies. The firm backs both established companies with early traction and development-stage ventures whose products or processes fit its investment themes. It supports portfolio companies by investing in revenue-driving areas such as sales, marketing and business development to accelerate customer engagement, brand equity and revenue growth. Cava Capital leverages industry and financial expertise to actively help build companies for long-term success and favorable risk-adjusted returns.

Regeneron Ventures is the corporate venture capital arm of Regeneron Pharmaceuticals, based in Greenwich, Connecticut. It focuses on strategic investments in the biopharmaceutical, healthcare, devices, tools, and health technology sectors, aiming to complement Regeneron's core business by identifying innovative early and growth-stage companies with potential synergies to Regeneron's scientific and commercial capabilities.

Oak HC/FT is a Stamford, Connecticut-based venture and growth equity firm that concentrates on healthcare information services and financial technology. It supports entrepreneurs with strategic counsel, board‑level participation, and access to an extensive network of industry leaders to drive transformation in these sectors. The firm draws on Oak Investment Partners’ sector expertise to build and grow innovative businesses, with a history of notable exits and large valuations. Founded in 2014, Oak HC/FT targets both growth‑stage and early‑stage companies in the United States, aiming to deliver strong value for investors.

Werth Ventures, based in Woodbridge, Connecticut, is a family office established in 2009 that makes investments across the healthcare sector, from seed to late-stage opportunities. The firm focuses on pharmaceuticals, biotechnology, medical devices, equipment, distribution, facilities, and managed health care, and participates in angel investing to support startup companies in pharmaceutical, veterinary, and medical device fields. Its activity includes funding projects aiming to develop cancer treatments, cardiovascular therapies, pain management, and innovative diagnostics and imaging technologies, as well as autoinjector devices and point-of-care tests. Werth Ventures seeks to back early and growth-stage ventures with potential to advance medical science and patient care.

Hillside Ventures is a venture capital firm based in Mansfield, Connecticut, founded in 2020. It makes early-stage investments in companies focused on sustainability, insurtech, and edtech, and it supports ventures connected to the University of Connecticut, including those founded by University of Connecticut alumni. The firm leverages a network of alumni for mentorship and guidance to help portfolio companies grow.

Longitude Capital is a private equity and venture capital firm specializing in life sciences, including pharmaceuticals, biotechnology, medical devices, and related tools and services. Founded in 2006 and headquartered in Menlo Park, California, with offices in Greenwich, Connecticut and Boston, it targets investments in US-based and international life science companies at startup through growth stages. The firm pursues venture growth opportunities in therapeutics, genomics, drug development, medical technology, R&D tools, diagnostics, and related health sectors. It backs both privately held and publicly traded companies and employs a range of structures including traditional venture investments, asset spin-outs, recapitalizations, PIPEs, royalties, and other equity-linked instruments. Longitude Capital seeks clinically de-risked assets with favorable risk-return profiles, aiming for exit within roughly three to five years and often taking lead or co-lead roles with a seat on the board. The approach emphasizes building a balanced portfolio across clinical- and commercial-stage assets to improve outcomes, reduce costs, and advance healthcare.

Safer Made is a venture capital firm based in North Branford, Connecticut, founded in 2017, focused on environmental impact by backing companies that remove or reduce harmful chemicals in products and manufacturing processes to promote healthier people and a cleaner world.

Bulldog Innovation Group, established in 2014 and based in New Haven, Connecticut, is dedicated to fostering early-stage ventures founded by Yale alumni. The organization aims to support entrepreneurs at the seed stage by providing experienced mentoring from a diverse network of Yale College and Yale School of Management graduates. By leveraging this robust community, Bulldog Innovation Group seeks to create significant opportunities for both entrepreneurs and investors. The firm primarily focuses its investments in sectors such as healthcare devices and supplies, software, healthtech, edtech, foodtech, mobile technology, robotics, and drones, positioning itself as a catalyst for innovation among Yale-affiliated startups. Bulldog Innovation Group operates independently of Yale University, emphasizing its commitment to building a vibrant entrepreneurial ecosystem.

Canaan Partners is a San Francisco-based venture capital firm founded in 1987 that operates globally with offices in Israel and India. It focuses on early-stage investments in technology and healthcare, including software, fintech, enterprise/cloud, marketplaces, digital health, biopharma, and medtech, and it has a history of backing startups that achieve exits.

Activant Capital is a Greenwich, Connecticut based private equity and venture capital firm with an additional office in Berlin, specializing in early to growth-stage investments in technology, e-commerce, retail, supply chain, fintech, healthcare, and related software and hardware sectors. Founded in 2015, the firm pursues opportunities across the United States and globally, with a focus on North America, and typically targets investments ranging from tens of millions of dollars in Series A to growth equity, recapitalizations, and later rounds. The firm partners with high-growth companies that are transforming commerce, including those in logistics, warehouse management, enterprise IoT, data services, and insurance, aiming to support scale and value creation through strategic collaboration and sector expertise.

CEI Ventures is the venture capital and private equity arm of Coastal Enterprises, a Brunswick, Maine-based investor established in 1994. It targets seed, startup, early-stage, mid-venture, recapitalization, and growth capital opportunities, focusing on companies in underserved markets across the Northeastern United States and New England, with a preference for Maine. The firm typically commits 250,000 to 1 million per financing, often in multiple rounds, and seeks exits in five to seven years. It aims to take a board seat in portfolio companies, supporting growth across sectors and business models as they scale.

Sageview Capital is a private equity investment firm headquartered in Greenwich, Connecticut, with additional offices in Palo Alto, California and Stockholm, Sweden. Founded in 2005, the firm focuses on growth and expansion investments in small and mid-sized companies across technology, financial services, and business services. Sageview emphasizes active ownership, board participation, and flexible capital structures to support growth, acquisitions, and strategic initiatives. The firm partners with management teams to drive value through operational improvements, add-on acquisitions, and capital efficiency, investing in both private and public companies in North America and Europe. Sageview collaborates with portfolio companies in sectors including enterprise software, fintech and IT-enabled services, aiming to hold investments for several years and tailor solutions to each situation.

Trident Capital is a venture capital and private equity firm founded in 1993 and headquartered in Palo Alto, California. The firm invests in software, services, internet, information technology security, healthcare IT, cloud computing, and related enterprise technology, spanning early venture through growth and late-stage opportunities. It seeks minority investments and may take control positions, often collaborating with co-investors on larger opportunities. While focused on North America, the firm has pursued investments in other regions and operates additional offices in San Mateo, California; Westport, Connecticut; and Delhi, India. Trident Capital emphasizes addressing major enterprise technology challenges through its portfolio, including IT security, analytics, SaaS, and mobile/cloud initiatives.

VC23 Investors is a venture capital firm based in Avon, Connecticut, United States. It focuses on early-stage investments in biotechnology, life science, technology, and healthcare, prioritizing management teams with breakthrough technologies. The firm seeks companies with potential to generate at least $100 million in annual revenue and often participates in rounds as a co-investor or leads rounds alongside others. It collaborates with other venture investors to pursue opportunities in technology and life sciences sectors and was founded in 2007.

SoundBoard Venture Fund is a venture capital and private equity firm based in Montclair, New Jersey, founded in 2011. It focuses on seed or pre-Series A and other early-stage investments, and may also consider more mature companies. The firm maintains a broad, industry-agnostic approach with emphasis on agriculture, manufacturing, infrastructure and transportation, real estate and construction, food and beverage, education, healthcare services (excluding pharmaceuticals and biotechnology), consumer products, and technology sectors. It often acts as a lead investor and aims to invest primarily within roughly 150 miles of metropolitan New York City, though regional opportunities may be considered. The firm adopts a collaborative investment model, mobilizing its investors to participate in evaluating companies and contributing diverse perspectives to the assessment process.

CHL Medical Partners is a United States-based venture capital firm that concentrates on seed and early-stage investments in healthcare and life sciences. Its portfolio spans biotechnology, molecular diagnostics, medical devices, healthcare services, and life sciences tools and services, with activity across the United States. The firm typically participates in initial rounds and may invest more over the life of an investment, often leading rounds and building a long-term syndicate of co-investors. It seeks board representation and may assume interim management roles in early-stage companies, while providing follow-on financing and support in raising additional capital. Exits are commonly realized through sales to strategic, financial, or public buyers. CHL Medical Partners was founded in 1997 and is based in Connecticut.

Realist Ventures is a venture capital firm based in Stamford, Connecticut, founded in 2018. It makes minority investments across multiple stages, from pre-seed and seed to later rounds, in technology-driven companies. The firm focuses on biotechnology, software, technology, and software as a service, with an emphasis on supporting bold founders and early-stage ventures across marketplace, internet, and software sectors.

Digital Currency Group is a Stamford, Connecticut-based corporate venture capital and investment firm focused on the digital currency and blockchain ecosystem. It provides funding and support to fintech and blockchain companies across bitcoin, web3 infrastructure, decentralized finance, data, metaverse, and related sectors, and it owns and operates notable subsidiaries including CoinDesk, a media and events platform; Genesis Trading, a bitcoin brokerage; and Grayscale Investments, a digital currency asset management firm.

Angel Investor Forum is a group of individual investors based in Lyme, Connecticut, established in 2004 to address the need for organized angel investing in the region. The forum focuses on providing funding for startup companies facing challenges in securing venture capital, particularly at the seed stage, where funding typically ranges from $250,000 to $5 million. Angel Investor Forum members leverage their financial resources, expertise, and networks to support companies with strong business models and significant growth potential. The group actively co-invests and collaborates with other angel groups and investment partners, targeting sectors such as software as a service, medical devices and diagnostics, biotechnology, energy, tonic water, and nanotechnology across the northeastern United States.

Signal Lake is a private equity and venture capital firm that invests across incubation, seed and later-stage ventures in technology companies. The firm focuses on software, communications and networking, broadband telecom, network infrastructure, information technology, cloud computing, embedded systems, semiconductors and green energy. It pursues global investment opportunities from a Northeast United States base, with offices in Westport, Connecticut and Boston, Massachusetts.

Nuveen Green Capital provides environmentally friendly financing for commercial real estate projects. Headquartered in Darien, Connecticut, the company was founded in 2015.

Braidwell is an investment firm founded in 2021 that invests in companies seeking to push the boundaries of medicine, science, and technology to transform human health. It relies on a seasoned team with expertise in investment research, medical science, biostatistics, commercial analysis, financial structuring, data and computer science, and portfolio engineering to evaluate opportunities and support growth.

QW Ventures is a growth-stage private investment firm headquartered in Beverly Hills, California, with additional offices in New York, Miami, and Connecticut. The firm focuses on investing in a diverse range of sectors, including fintech, security, cloud computing, marketplaces, mobile technologies, blockchain, and software as a service. QW Ventures aims to support technology-enabled businesses that demonstrate growth potential and innovation in these fields.

The Ropart Asset Management Funds is a Greenwich, Connecticut-based private equity firm founded in 2001 that invests in small to mid-sized companies across a range of sectors, including business services, financial services, healthcare services, consumer products and services, information technology, software, and emerging areas such as blockchain and cryptocurrency. The firm pursues growth and expansion investments in middle-market companies in the United States, often taking controlling positions and seeking board representation to support strategic growth. It employs a flexible capital approach that includes growth equity, mezzanine lending, and other private equity structures, and may pursue opportunistic investments in distressed or special situations. Through its funds, the firm aims to partner with management teams to scale operations, improve performance, and realize value creation across diverse industries.

Biomark Capital is a Greenwich, Connecticut-based private equity and venture capital firm focused on life sciences and healthcare. It makes investments across early, mid, and late stages in companies developing therapeutics, diagnostics, medical devices, molecular diagnostics, and digital health, as well as healthcare information technology. The firm targets opportunities in North America and Asia, with activity in Russia, Taiwan, India, and China. Formerly known as GBP Capital, Biomark Capital operates as a registered investment adviser and provides funding along with strategic support to accelerate growth for its portfolio companies.

Centripetal Capital Partners is a venture capital investment firm founded in 2004 and based in Stamford, Connecticut. The firm focuses on technology, health and wellness, impact, and market reimagination sectors.

Galen Partners is a Stamford, Connecticut-based private equity and venture capital firm founded in 1990 that concentrates on healthcare and related technology companies in the United States. The firm backs mid- to late-stage opportunities, including medical devices, diagnostics, healthcare information technology, life sciences, and other healthcare services, often partnering with experienced management teams to drive growth. Typical investments range around ten to thirty million dollars, with the firm capable of lead or co-investment positions and flexible ownership structures. Since its inception, Galen Partners has built a sizeable portfolio and, according to industry sources, has guided portfolio companies through public offerings, debt financings, mergers and acquisitions, and other liquidity events, contributing to a track record valued in the billions. The firm emphasizes leveraging healthcare expertise and a broad industry network to provide strategic resources and operational support to portfolio companies.

840 Venture Partners is a United States-based venture capital firm founded in 2021 and based in Greenwich, Connecticut. It focuses on seed and pre-Series A investments in FinTech, Future of Work, digital transactions and banking, automation, big data, and remote work. It targets disruptive innovation and leverages its industry network to source high-quality, off-market deal flow and provide portfolio companies with institutional-grade support.

Visary Capital is a venture capital firm founded in 2018 and based in Weston, Connecticut. It backs early-stage technology companies in fintech, data, cryptocurrency, artificial intelligence, the future of work, and digital industries, and also pursues digital asset strategies, macro opportunities, and selective venture investments.

NGN Capital is a venture capital firm founded in 2003 and headquartered in New York, with additional offices in Connecticut and Heidelberg, Germany. It targets late-stage investments with selective early- and mid-stage opportunities in the healthcare and biotechnology sectors, including drug products, pharmaceuticals, biopharmaceuticals, diagnostics, medical devices, and healthcare services. The firm invests in companies across the United States and Europe, supporting growth and development of therapies, devices, and diagnostic tools.

NGP Energy Capital Management is a private investment firm focused on energy. Founded in 1988 and based in Irving, Texas, it manages a family of private equity funds and makes direct equity investments across the oil and gas value chain, including production, acquisition, exploration and development drilling, midstream services, energy efficiency, and power technology, as well as related energy businesses. The firm also pursues opportunities in water resources and services, food and agriculture, and coastal protection. It primarily targets North American companies, including the United States, Canada, and parts of the Caribbean and Central America, with typical investment sizes from 2 million up to 500 million dollars. It may co-invest in direct oil and gas property interests alongside portfolio companies and maintains offices in Houston, London, Santa Fe, and Stamford to support a broad geographic reach.

10T Holdings is a growth equity investment firm focused on private companies in the digital asset ecosystem. It concentrates on financial services, venture capital, and investment management, providing capital and strategic support to growth-stage businesses in the cryptocurrency and blockchain sectors. Founded in 2019 and based in Greenwich, Connecticut, the firm seeks opportunities across the digital asset space by backing companies that enable financing, infrastructure, and services within the ecosystem.

Waypoint Capital Partners is a venture capital firm founded in 2001 and based in Stamford, Connecticut. As a private equity arm of Privet Capital, it focuses on providing entrepreneurs and businesses with both financial resources and strategic expertise. The firm is particularly interested in investments within the healthcare, SaaS, and manufacturing sectors. Waypoint Capital Partners emphasizes a flexible approach to structuring investments, tailoring solutions to the unique needs of its clients. Throughout the investment lifecycle, the firm remains committed to maintaining transparency and efficiency, ensuring that challenges are addressed promptly. Unlike traditional funds, Waypoint's decisions regarding exits prioritize the best interests of its management teams and portfolio companies rather than the imperative to return capital to limited partners.

Brand New Matter is a venture capital firm founded in 2013 and based in New York, with an additional office in Darien, Connecticut, that invests in enterprise technology, travel and hospitality, marketplaces, e-commerce, and consumer sectors.

Positive Sum is a venture capital firm founded in 2020 and based in Greenwich, Connecticut. The firm concentrates on early-stage investments and helps teams build extraordinary businesses.

Point72 Asset Management is a global investment manager led by Steven A. Cohen that invests across multiple asset classes and strategies, including discretionary long/short equities, quantitative approaches, macro strategies, and private investments. The firm serves pooled investment vehicles, launches and manages hedge funds, and uses fundamental analysis to guide its investments. It is headquartered in Stamford, Connecticut, with affiliated offices in New York, London, Poland, Hong Kong, Tokyo, and Singapore.

Bullish is a New York-based venture capital firm specializing in early-stage investments in consumer goods and retail companies. It backs B2C startups from pre-seed through Series A and maintains additional offices in Connecticut and Colorado.

1843 Capital is a venture capital firm founded in 2018 that backs early-stage technology companies, with a focus on enterprise software, cybersecurity, and Silvertech (technology for the aging population). The firm typically invests in Series A and B rounds and looks for teams that include at least one woman. It is based in Washington, DC, with additional offices in New York and Greenwich, Connecticut, and concentrates on companies addressing long-term healthspan and related technologies.

Altai Ventures is a venture capital firm founded in 2021 and based in Weston, Connecticut, focused on fintech investments across early and growth stages.

Agilic Capital is a Greenwich, Connecticut-based venture capital firm founded in 2014 by Greg Gilbert and Terry Darling. The firm provides flexible seed and growth capital to technology-related companies and supports startups and established lower-middle-market businesses with strategic partnerships and advisory services across industries including industrials, energy, consumer, technology, and financial sectors.

The Grosvenor Funds was a Washington, D.C.-based venture capital firm founded in 1994 that no longer invests. Historically it focused on seed, early, mid, and expansion-stage opportunities across the United States, with an East Coast emphasis. Its portfolio spanned technology and life sciences sectors, including wireless, broadband, IT services, online services, networking, security technology, healthcare services, pharmaceuticals, biotechnology, and defense-related IT. Typical initial commitments ranged around 1 to 2 million, with add-on financing in later rounds; the firm often acted as lead investor or formed syndicates and sought a board seat. It operated independently, with offices in Washington, D.C., and Greenwich, Connecticut.

NextGen Nutrition Investment Partners is a Greenwich, Connecticut-based venture capital firm founded in 2020 that invests in food technologies and ingredients designed to deliver superior nutrition to the food and beverage sector.

HealthInvest Equity Partners is a healthcare-focused investment firm founded in 2013 and based in Westport, Connecticut. The firm targets early-stage and growth-oriented opportunities within the healthcare sector, supporting startups and emerging healthcare services companies. Through its principals, HealthInvest has backed numerous healthcare services ventures and achieved notable exits, including American Renal Associates, Ascend Health, Odyssey Healthcare, Sempercare, and US Healthworks. The firm also maintains a portfolio of active investments, such as CareWell Urgent Care Centers of New England, Dicom Grid, Ella Health, Fidelis SeniorCare, and Medmark Services.

Established in 2022, Lifespan Vision Ventures is a venture capital firm headquartered in Norwalk, Connecticut. The company focuses on investing in therapeutics businesses that specialize in longevity and aging reversal.

Relayer Capital is a venture capital firm based in Stamford, Connecticut. It focuses on investing in the cryptocurrency and blockchain technology sectors, supporting companies that build infrastructure, protocols, and applications to drive mainstream crypto adoption.