Founded in 1989, Connecticut Innovations supports high-tech companies by providing strategic capital and operational insight. They focus on energy, biotechnology, information technology, and photonics sectors, offering flexible financing, guidance, and valuable partnerships to enable growth.

Advantage Capital Partners is a United States‑based venture capital firm that provides growth equity, debt, and mezzanine financing to small and mid‑market companies, with a focus on underserved communities and state and local economic development. The firm invests across sectors including manufacturing, technology, business services, life sciences, and energy, and also supports real estate development projects with equity and debt. It typically makes initial investments ranging roughly from half a million to ten million in companies with modest sales, and may participate in larger follow‑on rounds or co‑invest with other firms. It uses senior debt, mezzanine debt, subordinated loans, and government‑guaranteed lending, and often pursues equity positions through preferred shares or convertible notes. Advantage Capital operates nationwide in the United States, with roots in New Orleans and offices in multiple states, and has backed thousands of jobs and housing projects as part of its mission to expand inclusive economic growth.

Elm Street Ventures is a venture capital firm based in New Haven, Connecticut, focused on early-stage investments in life sciences, healthcare, and technology. It seeks opportunities rooted in intellectual property developed at Yale University and other regional research institutions spanning New York City to Southern New England. The firm targets therapeutics, medical devices, diagnostics, laboratory tools, materials, and healthcare services, as well as software, clean technologies, and sustainable innovations. Typical initial commitments range from hundreds of thousands to over a million dollars, with follow-on rounds as needed, and occasional syndication with other investors. Elm Street Ventures emphasizes strong patent protection, defensible market positions, and a world-class management team, and often leverages experienced entrepreneurs to support portfolio companies, including interim leadership when appropriate.

Founded in 1987, Canaan Partners is a global venture capital firm based in Menlo Park, California. With over $5 billion under management, the firm invests in early-stage technology and healthcare companies worldwide.

Fairview Capital Partners, established in 1994, is a prominent investment management firm specializing in private markets. Based in West Hartford, Connecticut, with an additional office in San Francisco, the firm offers expertise in venture capital, diverse and emerging managers, and direct co-investments. Fairview Capital manages over $10 billion in aggregate fund capitalization, investing on behalf of institutional clients such as foundations, endowments, pension plans, and family offices. Known for its entrepreneurial approach, diverse leadership, and inclusive investment strategy, the firm is one of the largest minority-owned investment companies in the U.S.

Cava Capital is a venture capital firm founded in 2008 and based in Darien, Connecticut. The firm targets investments in consumer health and wellness, mobile, marketing technology, software as a service, and active lifestyle markets, aligning with themes around the rise of the consumer, evolving marketing dynamics, and the importance of brand and technology in scalable companies. It invests in both established companies with early traction and development-stage ventures whose products fit its themes, with a focus on expanding revenue drivers such as sales, marketing, and business development to engage customers, strengthen brand equity, and drive growth. Cava Capital seeks to maximize long-term, risk-adjusted returns by actively building portfolio companies through its industry expertise, management resources, and financial acumen. The firm often leads or plays a significant role in investment opportunities, leveraging its experience to support growth and execution.

Activate Venture Partners is a New York–based venture capital firm focused on early-stage and growth investments in software, data, and technology-enabled services, with a particular emphasis on digital health and healthcare IT, fintech, and enterprise technology. The firm backs technology-enabled service businesses offering software as a service, data-as-a-service, mobile apps, and related platforms, and seeks to invest in companies serving providers, payors, biopharmaceutical firms, and patients. It targets opportunities in the Northeast and Mid-Atlantic, especially the Greater New York area, New Jersey, Connecticut, Eastern Pennsylvania, and neighboring markets, and tends to invest in initial rounds ranging from roughly $0.75 million to $3 million, preferring deals that require under $5 million to reach profitability. Activate often leads or co-leads investments, takes a board seat, and assists with follow-on equity rounds and financing. The firm has a history of digital health activity and software and data provenance across its portfolio, underscoring its focus on scalable technology-enabled solutions rather than medical devices or drugs.

Founded in 2009, Werth Ventures is a family office that invests in seed to late-stage healthcare companies. Its focus areas include pharmaceuticals, biotechnology, medical devices, and diagnostics.

Oak HC/FT is a venture and growth equity investment firm specializing in healthcare information services and financial technology. It supports portfolio companies with strategic counsel, board-level participation, and access to a broad network of industry leaders to drive transformation in these sectors. The firm, based in Stamford, Connecticut, operates within the Oak Investment Partners family, leveraging sector-specific expertise from Oak's healthcare and fintech teams to build and scale innovative businesses.

Trident Capital is a venture capital and private equity firm founded in 1993 and headquartered in Palo Alto, California, with additional offices in San Mateo, Westport and Delhi. It concentrates on early venture, growth equity, and buyout opportunities in software, services, information technology and Internet sectors, including enterprise software, IT security, cloud computing, Healthcare IT, adtech, mobile, and analytics. The firm pursues North American investments with select activity in Asia, China, Sweden, Finland and India, typically committing from about $0.25 million up to $20 million in growth capital and often seeking a minority stake but may take control in some cases. It collaborates with other value-added investors on larger opportunities and focuses on firms addressing cloud computing, digital monetization, cybersecurity, online travel, data management, and related IT infrastructure and services. The firm aims to help portfolio companies scale and compete in rapidly evolving technology markets.

Founded in 2017, Safer Made is a venture capital firm based in North Branford, Connecticut. It invests in companies that aim to remove or reduce the use of harmful chemicals in products or manufacturing processes.

Activant Capital, established in 2015, is a global investment firm headquartered in Greenwich, Connecticut, with an additional office in Berlin, Germany. The firm specializes in venture capital and private equity investments, focusing on high-growth companies that are transforming commerce, particularly in the technology, e-commerce, supply chain, retail infrastructure, logistics, financial technology, insurance, and healthcare sectors. Activant Capital typically invests between $20 million to $40 million in series A, B, and C rounds, as well as growth equity and recapitalizations, with a global investment scope, primarily in North America.

Bulldog Innovation Group, established in 2014 and based in New Haven, Connecticut, is dedicated to fostering early-stage ventures founded by Yale alumni. The organization aims to support entrepreneurs at the seed stage by providing experienced mentoring from a diverse network of Yale College and Yale School of Management graduates. By leveraging this robust community, Bulldog Innovation Group seeks to create significant opportunities for both entrepreneurs and investors. The firm primarily focuses its investments in sectors such as healthcare devices and supplies, software, healthtech, edtech, foodtech, mobile technology, robotics, and drones, positioning itself as a catalyst for innovation among Yale-affiliated startups. Bulldog Innovation Group operates independently of Yale University, emphasizing its commitment to building a vibrant entrepreneurial ecosystem.

Malin Corporation plc is an Irish public limited company established in 2015, with its headquarters in Dublin and additional offices in New Haven, Connecticut, and Research Triangle, North Carolina. The company specializes in venture capital investments, focusing on innovative enterprises within the life sciences and healthcare technology sectors, particularly in oncology, immunology, and genetic diseases. Malin's strategy involves the selective application of capital and operational expertise to support private, pre-IPO, and pre-trade sale businesses in rapidly growing markets. By actively engaging with its investee companies, Malin aims to enhance their value propositions and facilitate their journey toward commercial success.

Founded in 2005, Sageview Capital is a private equity and venture capital firm specializing in growth equity investments. It focuses on tech-enabled businesses across financial services, business services, and technology sectors, typically investing between $15 million to $100 million in companies with revenues ranging from $10 million to $50 million. Based in Greenwich, Connecticut, with additional offices in Palo Alto, California, the firm seeks majority or minority stakes and aims to hold investments for three to seven years.

VC23 is a venture capital firm based in Avon, Connecticut, that specializes in early-stage investments primarily in the biotechnology and technology sectors. Founded in 2007, the firm targets companies with the potential to generate at least $100 million in annual revenues. VC23 is dedicated to identifying and structuring investments in innovative management teams and breakthrough technologies. The firm demonstrates versatility by either leading capital rounds or participating as a co-investor alongside other venture capital firms and early-stage investors. This collaborative approach enables VC23 to leverage partnerships while driving growth in the companies it supports.

Founded in 2002, Sopris Capital is a venture capital firm specializing in seed to growth stage investments. It focuses on technology-enabled services and healthcare businesses across the United States and Canada.

CHL Medical Partners is a venture capital firm focusing on seed and early-stage investments in the life sciences and healthcare sectors in the United States. It backs companies across biotechnology, molecular diagnostics, medical devices, life sciences tools and services, and healthcare delivery innovations, including consumer healthcare and elder-care solutions. The firm typically acts as lead investor, aims to build long-term co-investment syndicates, seeks board representation, and may take interim management roles in seed investments. It provides follow-on financing and helps portfolio companies raise capital in public and private markets. Investment activity generally targets early-stage opportunities, with a history of supporting companies through initial rounds and exits via acquisitions or other buyers. CHL Medical Partners was founded in 1997 and is based in Connecticut.

Founded in 2018, Realist Ventures is a venture capital firm based in Stamford, Connecticut. It invests in early-stage companies focused on marketplace, internet, technology, and software sectors.

Founded in 2004, New Science Ventures is a venture capital firm based in Greenwich, Connecticut. It focuses on early-stage investments in life sciences and information technology sectors globally.

Digital Currency Group is a Stamford, Connecticut-based corporate venture capital firm that invests in and supports companies operating in fintech, bitcoin, web3 infrastructure, platforms, decentralized finance, data, metaverse, and blockchain sectors. Through its portfolio, the firm provides capital and strategic guidance to a global network of startups and mature ventures. Digital Currency Group also owns and operates CoinDesk, a prominent blockchain media and events platform, Genesis Trading, a leading bitcoin brokerage, and Grayscale Investments, a major digital asset management firm, which together extend its ecosystem beyond investment into media, trading, and asset management services.

Angel Investor Forum is a group of individual investors based in Lyme, Connecticut, established in 2004 to address the need for organized angel investing in the region. The forum focuses on providing funding for startup companies facing challenges in securing venture capital, particularly at the seed stage, where funding typically ranges from $250,000 to $5 million. Angel Investor Forum members leverage their financial resources, expertise, and networks to support companies with strong business models and significant growth potential. The group actively co-invests and collaborates with other angel groups and investment partners, targeting sectors such as software as a service, medical devices and diagnostics, biotechnology, energy, tonic water, and nanotechnology across the northeastern United States.

Longitude Capital is a California-based investment firm focused on venture growth in life sciences, including biotechnology and medical technology companies. Founded in 2006, it targets both privately held and publicly traded life science companies and pursues a balanced portfolio of clinical-stage and commercial-stage assets with the potential for value creation within three to five years. The firm identifies opportunities through its broad industry network and thematic research into emerging therapeutic areas or sub-sectors, and uses a range of investment structures including traditional venture capital, asset spin-outs, recapitalizations, PIPEs, open market purchases, royalties, and other equity-linked instruments. It maintains offices in Menlo Park, Greenwich, and Boston and operates as a registered investment adviser.

Signal Lake Management is a private equity and venture capital firm headquartered in Westport, Connecticut, with an additional office in Boston, Massachusetts. The firm specializes in making investments across various stages, including incubation, seed, early, mid, and late venture funding. Signal Lake typically invests between $100,000 and $100 million in its portfolio companies, focusing primarily on sectors such as broadband telecom, network infrastructure, green energy, information technology, software, cloud computing, and semiconductors. While it emphasizes opportunities in the Northeast region of the United States, Signal Lake also pursues investments on a global scale.

Deep Track Capital is a venture capital firm focused on life sciences and biotechnology. Based in Greenwich, Connecticut, it partners with management teams of innovative public and pre-IPO companies, offering capital and strategic support through its network and expertise. The firm aims to lead transactions, form large syndicates, and participate in rounds led by other investors, applying time and resources to help portfolio companies grow.

Atlas Innovate is the venture capital arm of Atlas Holdings, based in Connecticut. Founded in 2018, it makes early-stage investments in industrial technology companies addressing major industry challenges and opportunities. The firm leverages Atlas Holdings’ network to provide portfolio companies with insights into product-market fit, supplier and customer relationships, manufacturing expertise, and access to talent, supporting activities from due diligence to exit. Atlas Innovate seeks to accelerate the commercialization of transformative industrial technologies by linking entrepreneurs with industry experts and direct channels to customers and suppliers.

Founded in 2003, NGN Capital is a venture capital firm specializing in late-stage investments with selective participation in mid and early stages. It focuses on the healthcare and biotechnology sectors, investing primarily in companies based in the United States and Europe.

NGP Energy Capital Management is a private equity and venture capital firm focusing on energy investments. Founded in 1988 and headquartered in Irving, Texas, with offices in Houston, London, Santa Fe, and Stamford, it manages a family of energy-focused funds. The firm invests across the energy value chain, including oil and gas exploration and production, midstream, oilfield services, energy efficiency, alternative energy, natural gas gathering and processing, and power technology, as well as related areas such as water resources, food and agriculture, and coastal protection. It targets a range of capital events from seed and startup funding to growth equity, middle-market and later-stage buyouts, and may co-invest in direct oil and gas property interests alongside portfolio companies. Typical investments span from a few million to several hundred million dollars, with a North American focus and selective international opportunities. The firm aims to partner with management teams to support growth and help navigate the challenges of the energy industry.

TWJ Capital, founded in 2005 and based in Stamford, Connecticut, is a growth equity investment firm that specializes in providing capital to early and expansion stage companies. The firm primarily focuses on sectors such as telecommunication software, internet marketing software, business service software, and specialty retail. Its investment strategy includes growth equity, venture capital for start-ups and early-stage companies, as well as recapitalizations and leveraged buy-outs in the lower middle market. The typical investment range is between $500,000 and $5 million, with transactions generally not exceeding $25 million. TWJ Capital maintains a medium-term investment horizon of three to four years, emphasizing thorough due diligence that evaluates the quality of company management and identifies clear growth catalysts and exit strategies. The portfolio is approximately composed of 40% growth equity, 40% early-stage investments, and 20% recapitalizations and buy-outs.

P5 Health Ventures, LLC is a venture capital firm established in 2015 and located in Fairfield, Connecticut. The firm specializes in investing in seed, early, and mid-stage health technology companies that focus on various aspects of healthcare, including disease management, consumer-driven healthcare, population health management, diagnostics, telehealth, remote monitoring, and nutrition. P5 Health Ventures aims to support innovations that enhance the accessibility and quality of healthcare while reducing costs. The firm is particularly interested in companies that effectively translate research and technology into practical healthcare solutions. Its investment strategy primarily targets opportunities within the United States.

Atlas Venture L.P. is a private equity and venture capital firm specializing in investments startups, seed, early stage, turnaround, late venture, growth capital and incubation. It seeks to invest in the technology and life sciences sectors with a focus on personalized medicine, medical technologies, therapeutics, biopharmaceutical products, biotechnology, biology, drug discovery technologies, therapeutic platforms, novel biopharmaceutical products, novel therapeutics, novel drug discovery platforms, therapeutic products, innovative biomedical technologies, diagnostics, and medical devices. Within technology, the firm focuses on payments, SMB, consumer-facing innovation, advances in biology, next-generation infrastructure, security, consumer services, small business infrastructure, fintech, emerging web service companies, next-generation media, gaming, and social technologies, enterprise and internet infrastructure, big data and mobile infrastructure, internet related businesses and communications. Within life sciences, it focuses on biopharmaceuticals. It also invest in silicones, consumer discretionary, and internet and direct marketing retail, internet software and services, IT services, security software, memory chips, and broadband telecommunication services. The firm prefers to invest in companies based in the Europe and United States with a focus on New England, Boston, Maine, Connecticut, New Hampshire, Rhode Island, Vermont, California and San Francisco Bay Area. Its initial investment ranges from $0.25 million to $15 million per transaction. The firm prefers to be a lead investor and seeks a board representation in its portfolio companies. Atlas Venture L.P. was founded in 1980 and is headquartered at Cambridge, Massachusetts with an additional office in London, United Kingdom.

Founded in 2013, Brand New Matter is a venture capital firm based in New York, with an additional office in Darien, Connecticut. The firm invests in early-stage companies across various sectors including enterprise tech, travel and hospitality, marketplace, e-commerce, and consumer.

Founded in 2021, Braidwell invests in innovative companies that aim to advance medicine, science, and technology to improve human health. Led by a team with extensive experience in investment research, medical science, biostatistics, commercial analysis, financial structuring, data/computer science, and portfolio engineering.

WFA Global Investments is a venture capital firm based in New York, with an additional office in Wilton, Connecticut. It focuses on early-stage investments in technology-enabled sectors such as deep tech, quantum computing, AI, cybersecurity, drones, robotics, fintech, blockchain, IoT, and real estate technology. The firm targets global opportunities and pursues long-term growth through a multi-strategy approach across private and public markets. It emphasizes sustainability, financial stability, and social responsibility in its investment approach, backing innovative firms delivering nimble solutions in an evolving global landscape.

Innovating Capital is a venture capital firm backed by a family office that invests in disruptive technologies across enterprise sectors. Based in New York City, with activities in Greenwich, Connecticut, it supports start-ups through growth-stage companies in areas including enterprise infrastructure, digital health, manufacturing, cybersecurity, financial technologies, and insurance technology, seeking to back ventures with potential for scale and impact.

Point72 Ventures is a global venture capital firm and the independent investment arm of Point72, the asset management firm led by Steven A. Cohen. It invests primarily in fintech, artificial intelligence and machine learning, and enterprise technologies, while also backing companies in deep tech, healthcare, mortgage tech, and adtech across all growth stages. The firm operates from offices in New York City, Palo Alto, San Francisco, and Stamford, Connecticut, reflecting its cross-border reach and emphasis on data-driven software and scalable technology solutions. Founded in 2016, Point72 Ventures supports innovative startups through strategic capital and domain expertise.

Skyline Ventures is a Palo Alto-based venture capital firm founded in 1997 that specializes in early-stage investments in healthcare and life sciences. The firm backs companies developing small molecule and protein therapeutics, medical devices, diagnostics, and technologies that enable drug discovery and life science research. It aims to back product-focused ventures with meaningful intellectual capital and proven pathways to clinical or commercial milestones, and it typically invests $15 million to $35 million over the life of a portfolio company, often leading or co-leading its first or second institutional rounds and taking board seats. Skyline emphasizes data-driven decision making, focusing on proof of principle, validation, and the quality of management and market opportunity. While primarily US-focused, it maintains offices in Boston and Stamford in addition to its Palo Alto base.

Waypoint Capital Partners is a venture capital firm founded in 2001 and based in Stamford, Connecticut. As a private equity arm of Privet Capital, it focuses on providing entrepreneurs and businesses with both financial resources and strategic expertise. The firm is particularly interested in investments within the healthcare, SaaS, and manufacturing sectors. Waypoint Capital Partners emphasizes a flexible approach to structuring investments, tailoring solutions to the unique needs of its clients. Throughout the investment lifecycle, the firm remains committed to maintaining transparency and efficiency, ensuring that challenges are addressed promptly. Unlike traditional funds, Waypoint's decisions regarding exits prioritize the best interests of its management teams and portfolio companies rather than the imperative to return capital to limited partners.

Founded in 2019, 10T Holdings is a growth equity fund based in Greenwich, Connecticut. It invests in private companies operating within the digital asset ecosystem, focusing on financial services, venture capital, and investment management.

Oak Investment Partners is a Connecticut-based multi-stage venture capital and private equity firm founded in 1978. It targets high-growth opportunities in information technology, internet and consumer sectors, financial services technology, healthcare information and services, and clean energy. The firm engages in buyouts, spinouts, growth equity, mid-to-late stage financings, and private investments in public equity, as well as startup and emerging growth ventures, recapitalizations, and industry consolidation. Typical investments range from ten to one hundred fifty million dollars. Oak primarily invests in the United States with selective activity in Europe, Israel, India, South Korea and China. It maintains offices in Connecticut, California and Minnesota, and has deployed billions of capital across hundreds of companies, offering senior guidance and sector expertise.

Thynk Ventures is a venture capital firm based in Stamford, Connecticut that focuses on early-stage investments in technology-enabled startups. The firm targets companies working in machine learning, artificial intelligence, mobile, digital platforms, and software-as-a-service, with a focus on opportunities in the New York City area. In addition to capital, Thynk Ventures provides hands-on, early-stage support to portfolio companies, including guidance on ideation, product development, go-to-market strategies, pricing, partnerships, fundraising, and exits. The firm backs ventures at the intersection of technology and scalable solutions, helping founders navigate growth and move from concept to market success.

Connectivity Capital Partners is a venture capital firm focused on seed, startup and early venture investments, with a concentration in health and financial services. Founded in 2015, it is based in Weston, Connecticut, and has an additional office in New York, New York.

840 Venture Partners is a United States-based venture capital firm focused on seed and pre-Series A investments in FinTech, automation, big data, digital transactions and banking, and Future of Work. Drawing on more than 13 years of venture experience, the firm supports startups at the outset of growth by leveraging an extensive industry network and providing strategic guidance and resources. Based in Greenwich, Connecticut, it seeks to back disruptive companies that advance digital transactions, data-driven platforms, and remote work capabilities, helping founders scale during their early stages.

SAS Investors was a venture capital firm based in New York City, established in January 2001, that specialized in seed and early-stage investments primarily in technology companies located in the Mid-Atlantic and Northeast regions of the United States. The firm focused on states such as New York, New Jersey, Connecticut, Maryland, Delaware, Pennsylvania, Massachusetts, and Rhode Island. Typically, SAS Investors made initial investments of up to $1.25 million, with a total commitment of up to $3 million over the life cycle of a portfolio company. It preferred to be the first institutional investor in its target companies and often sought co-investment opportunities. The firm aimed to support unique and defensible technology ventures by leveraging its resources and experience to assist portfolio companies in developing effective go-to-market strategies, understanding industry dynamics, and maximizing the potential of their intellectual property. SAS Investors, backed by notable venture capital firms, positioned itself as a leading supporter of core technology companies in its targeted regions. However, it is no longer actively investing.

Eastven Venture Partners, established in 2000 and based in Darien, Connecticut, is a venture capital firm that specializes in telecommunications technology investments across North America and Europe. Initially known as Ericsson Venture Partners, the firm was the exclusive venture capital vehicle for Ericsson, a leading provider of wireless network equipment. As an independent entity, Eastven leverages its extensive industry experience and strong relationships with key players such as Ericsson and Sony-Ericsson, along with financial institutions and global operators, to enhance the value of its portfolio companies. The firm targets companies at all stages of development, focusing on proprietary technologies in areas such as applications, network infrastructure, software, and semiconductors.

MissionPoint Partners, established in 2006 and headquartered in Westport, Connecticut, is an asset management firm specializing in venture capital investments. The company focuses on high-growth opportunities in the clean energy and environmental finance sectors, driven by the global transition to a low-carbon economy. Their investment strategy targets companies addressing climate change mitigation, waste recycling, local food systems, and urban water infrastructure across the United States. MissionPoint Partners raised its first fund, MPCP Fund I, in 2007 with $335 million, backed by a diverse range of sophisticated investors including high net worth individuals, institutions, and foundations.

Founded in 2004, Centripetal Capital Partners is a venture capital firm based in Stamford, Connecticut. The firm invests primarily in the technology and health & wellness sectors.

Centricap is a venture capital firm headquartered in Stamford, Connecticut, that invests between $2-7 million in growth and early-stage companies. Established in 2004 and formerly known as Centripetal Capital Partners, Centricap adopts an opportunistic growth capital investment approach. The firm targets revenue-generating companies with proprietary advantages, proven business models, and experienced management teams. Its investment focus spans technology, health and wellness, impact sectors, and market reimagination, providing greater flexibility and opportunities for its limited partners compared to traditional funds.

Synchrony Financial is a consumer financial services company in the United States that provides a range of financing programs and banking products tailored to retail, digital, home, auto, travel, health, and pet industries. The firm offers private label credit cards, dual and co-branded general-purpose cards, installment lending, and promotional financing for consumer purchases, along with debt cancellation products. It also provides deposit products such as certificates of deposit, individual retirement accounts, money market accounts, and savings accounts via digital and traditional channels. Synchrony partners with national and regional retailers, local merchants, manufacturers, buying groups, industry associations, and healthcare providers to market its credit and deposit offerings. The company operates through multiple programs and channels to reach both retail and commercial customers. Founded in 2003, Synchrony is headquartered in Stamford, Connecticut.

Founded in 2019, Acadian Ventures is a global venture capital firm that invests in early-stage companies leading the work revolution. They focus on software-as-a-service (SaaS) firms that aim to make work better, fairer, more meaningful, and ultimately more productive.