Connecticut Innovations

Normunity is a biotechnology company focused on developing precision immuno-oncology medicines, specifically a new class known as immune normalizers. These medicines aim to target novel mechanisms that enhance the body’s natural immune response against cancer. In collaboration with the lab of Dr. Lieping Chen at Yale School of Medicine, Normunity is researching newly-discovered mechanisms of immune disruption in cancer, utilizing proprietary discovery platforms to explore the intricate interactions between cancer and the immune system. The company is advancing a pipeline of immune normalizers, which includes initial drug programs designed to address the exclusion of T-cells from immune-sensitive tumors and other factors that impede normal immune function in cancer. Normunity operates from locations in Boston, Massachusetts, and West Haven, Connecticut.

Quantum Circuits, Inc. specializes in the development and manufacture of quantum computers utilizing superconducting devices. Founded in 2015 and located in New Haven, Connecticut, the company aims to innovate in the field of quantum computing by delivering full-stack systems that efficiently scale. Led by Dr. Robert Schoelkopf, a prominent figure in quantum science, Quantum Circuits employs a unique dual-rail quantum qubit design that incorporates built-in hardware error detection and conversion. This approach allows for a highly scalable error-corrected system, requiring significantly fewer physical qubits per logical qubit and providing a more efficient pathway to fault-tolerant quantum computing. By focusing on solid-state quantum bits, the company enables clients to perform error-free computations, thereby accelerating research and advancing the practical applications of quantum technology.

IntelliBoard, Inc. is a developer of a learning analytics platform focused on delivering insights and reporting services to educational institutions and corporate clients. Founded in 2015 and based in Monroe, Connecticut, IntelliBoard's platform integrates with various Learning Management Systems (LMS) to provide comprehensive data analysis tools. These tools enable faculty and management to access real-time data on learner engagement, performance, and the effectiveness of educational content. By presenting statistical data in an accessible format, including charts and formatted reports, IntelliBoard helps institutions make informed decisions, improve learning outcomes, and enhance operational efficiency. The company's mission is to empower clients to achieve their educational goals and maximize the return on their e-learning investments.

Slooh, LLC, founded in 2003 and based in Washington Depot, Connecticut, offers an innovative platform for public engagement in astronomy by providing online access to robotic telescopes located in various observatories worldwide. The company connects these telescopes to the internet, allowing users to view celestial events in real-time and participate in astronomical discoveries. Slooh has developed partnerships with institutions such as NASA and the Institute of Astrophysics of the Canary Islands, enhancing its credibility in the field. Through its automated observatories, Slooh has facilitated the capture of millions of celestial images and has broadcast live events like eclipses and asteroid observations, featuring expert narration. The platform is geared towards making astronomy accessible and affordable, particularly for educational institutions, enabling students and the public to explore the universe collaboratively with guidance from astronomy educators.

Inbox Health Corp. is a digital healthcare company that focuses on improving patient communication regarding medical billing in the United States. Established in 2014 and based in New Haven, Connecticut, the company offers a platform that automates the patient communication process through bi-directional correspondence and advanced technologies such as machine learning and artificial intelligence. This platform helps patients better understand their medical bills and provides various payment options. By analyzing data from its customer base, Inbox Health enables medical billers to customize the billing and communication experience for each patient, thereby enhancing collections and overall patient satisfaction. The company's mission is to reduce administrative inefficiencies in healthcare by streamlining the billing and payment processes for patients.

Torigen Pharmaceuticals is dedicated to advancing cancer care for companion animals through innovative treatment options. Founded in 2013 and based in Farmington, Connecticut, the company focuses on developing immunotherapy solutions, particularly an experimental autologous cancer vaccine. This vaccine aims to activate the immune system to target specific tumor-associated antigens present on cancer cells, allowing for more effective detection and treatment of tumors. By providing alternatives to traditional, invasive methods such as surgeries and chemotherapy, Torigen seeks to improve the quality of life for pets facing cancer. The company builds on years of scientific research and is committed to pushing the boundaries of veterinary oncology.

NourishedRx is a provider of personalized food solutions aimed at health plan members and patients with diet-sensitive chronic health conditions, particularly those experiencing nutrition insecurity. Founded in 2019 in Stamford, Connecticut, the company delivers customized meal plans and meal prep kits tailored to individual eating habits. In addition to food solutions, NourishedRx offers educational resources and support to promote lasting behavior change, ultimately enhancing member engagement and satisfaction. The company's approach is designed to improve clinical outcomes and deliver significant cost savings for both individuals and healthcare systems.

Wellinks, Inc., based in New Haven, Connecticut, specializes in wearable health technology aimed at improving clinical outcomes. Initially founded as 109 Design LLC in 2014, the company develops innovative devices for managing conditions such as scoliosis and chronic obstructive pulmonary disease (COPD). Wellinks offers a smart strap that enables patients, parents, and healthcare providers to monitor the duration and fit of scoliosis braces, thereby preventing the need for surgeries. The technology provides real-time data and feedback, empowering users to make informed decisions about their treatment. Additionally, Wellinks focuses on individualized care for COPD patients, offering digital health systems that support remote monitoring and management of respiratory conditions, enhancing patient engagement and health outcomes. The company operates as a subsidiary of Convexity Scientific Inc.

Lumeda Inc. is a biotechnology company focused on developing advanced photonic tools for intraoperative photodynamic therapy (PDT) to treat lung cancer. Founded in 2020 and based in Rocky Hill, Connecticut, the company aims to enhance the efficacy and ease of PDT procedures. Lumeda's innovative solutions include light delivery instrumentation and proprietary software that automates the delivery of light to targeted tumors with precise dosimetry profiles. By integrating advanced photonics with artificial intelligence, Lumeda's technology improves treatment planning and performance, allowing for a streamlined and reliable intraoperative PDT procedure. This approach not only addresses tumor margins during conventional non-small cell lung cancer resections but also seeks to reduce post-operative recurrence and improve overall patient outcomes.

Inbox Health Corp. is a digital healthcare company that focuses on improving patient communication regarding medical billing in the United States. Established in 2014 and based in New Haven, Connecticut, the company offers a platform that automates the patient communication process through bi-directional correspondence and advanced technologies such as machine learning and artificial intelligence. This platform helps patients better understand their medical bills and provides various payment options. By analyzing data from its customer base, Inbox Health enables medical billers to customize the billing and communication experience for each patient, thereby enhancing collections and overall patient satisfaction. The company's mission is to reduce administrative inefficiencies in healthcare by streamlining the billing and payment processes for patients.

Artizan Biosciences, Inc. is a biotechnology company based in New Haven, Connecticut, founded in 2016. The company focuses on developing small molecule drugs aimed at treating serious diseases linked to intestinal inflammation. Utilizing its proprietary IgA-SEQ technology platform, Artizan distinguishes disease-driving bacteria within the intestinal microbiota. This innovative approach enables the development of precision therapeutics designed to address unmet medical needs in various conditions, including digestive disorders, obesity, autoimmune diseases, and disorders affecting the skin, lungs, and central nervous system. Through its research, Artizan aims to provide new and potentially curative treatment options for patients suffering from these diverse health challenges.

Biorez, Inc. is a medical device company specializing in the development of bioresorbable scaffold implants aimed at regenerating functional tissue in vivo. Founded in 2008 and based in New Haven, Connecticut, Biorez offers innovative products such as an off-the-shelf implant for anterior cruciate ligament (ACL) reconstruction, which eliminates the need for harvesting donor tissue and serves as a superior alternative to cadaver-based materials. The company's technology utilizes a degradable polymer, specifically PLLA, to create implants that stabilize surgical repairs and facilitate the body's natural tissue regeneration, thereby enhancing musculoskeletal outcomes. Among its product lineup is the L-C Ligament® and the biorez GRAFT™, an FDA-cleared device designed for soft tissue augmentation of the rotator cuff. By leveraging this technology, Biorez aims to accelerate patient recovery and improve surgical outcomes in orthopedic procedures.

Simcha Therapeutics is a biopharmaceutical company developing engineered cytokine immunotherapy for cancer. The company uses directed evolution to engineer novel cytokines designed to unlock the precision and power of the immune system. Simcha’s lead program, ST-067, is a designer IL-18 cytokine that has shown potent antitumor effects in animal models, both as a monotherapy and when combined with anti-PD-1 checkpoint inhibitors, as described in Nature in June 2020. It was founded in 2018 and is headquartered in New Haven, Connecticut, USA.

IntelliBoard, Inc. is a developer of a learning analytics platform focused on delivering insights and reporting services to educational institutions and corporate clients. Founded in 2015 and based in Monroe, Connecticut, IntelliBoard's platform integrates with various Learning Management Systems (LMS) to provide comprehensive data analysis tools. These tools enable faculty and management to access real-time data on learner engagement, performance, and the effectiveness of educational content. By presenting statistical data in an accessible format, including charts and formatted reports, IntelliBoard helps institutions make informed decisions, improve learning outcomes, and enhance operational efficiency. The company's mission is to empower clients to achieve their educational goals and maximize the return on their e-learning investments.

CytoVeris is a company focused on developing optical-based technologies to assist surgical oncologists in identifying and removing tumor tissue during cancer resection surgeries. Founded in 2018 by Alan Kersey in Farmington, Connecticut, CytoVeris aims to enhance the surgeon's ability to achieve clean margins, thereby improving patient outcomes. The company’s devices facilitate real-time assessment of tissue and generate molecular-specific information by detecting unique signatures created by cancer cells that alter cellular metabolic processes. This includes variations in lipids, proteins, and metabolites, which can be identified using their OncoMap system. By providing oncologists with critical information during surgery, CytoVeris seeks to reduce healthcare costs associated with repeat surgeries.

MindNest Health, Inc. is a Connecticut-based company founded in 2016 that develops a digital platform for parent training, enabling caregivers to implement clinically validated behavioral interventions for children with conditions such as ADHD, autism, and disruptive behaviors. The platform aims to promote children's development by providing evidence-based solutions that address behavioral health challenges, including anxiety and depression. MindNest Health's approach seeks to eliminate barriers parents face when seeking help, thereby enhancing access to care for their children and reducing stress for families. Additionally, the company is focused on decreasing the overall cost of care for employers and payers, with a vision of fostering an environment where children and families can thrive.

Inbox Health Corp. is a digital healthcare company that focuses on improving patient communication regarding medical billing in the United States. Established in 2014 and based in New Haven, Connecticut, the company offers a platform that automates the patient communication process through bi-directional correspondence and advanced technologies such as machine learning and artificial intelligence. This platform helps patients better understand their medical bills and provides various payment options. By analyzing data from its customer base, Inbox Health enables medical billers to customize the billing and communication experience for each patient, thereby enhancing collections and overall patient satisfaction. The company's mission is to reduce administrative inefficiencies in healthcare by streamlining the billing and payment processes for patients.

Enviro Power, LLC, founded in 2013 and based in Hartford, Connecticut, specializes in the development and marketing of innovative heating equipment for both residential and commercial applications. The company offers two main products: the Commercial SmartWatt Boiler, designed for light-commercial and high-end residential settings, and the Residential SmartWatt Boiler for home use. Enviro Power's SmartWatt Boiler technology platform not only meets heating requirements but also generates electricity at nearly zero cost, providing backup power and enhancing grid stability. This system allows building owners to potentially reduce utility bills while simultaneously lowering their carbon footprint and contributing to improved grid resiliency.

IsoPlexis is a life science technology company based in Branford, Connecticut, founded in 2013. It focuses on developing a single-cell detection system that identifies patient immune responses at the single-cell level. This innovative platform enables the assessment of therapeutic safety and efficacy, as well as the monitoring of disease progression. IsoPlexis specializes in cell-based proteomic systems and biomarkers, providing insights into functional protein biology and cellular signaling networks with high resolution. By offering these capabilities, the company aids in predicting patient responses to novel immunotherapies and cellular therapies, ultimately enhancing therapeutic development and informing clinical decisions.

Wellinks, Inc., based in New Haven, Connecticut, specializes in wearable health technology aimed at improving clinical outcomes. Initially founded as 109 Design LLC in 2014, the company develops innovative devices for managing conditions such as scoliosis and chronic obstructive pulmonary disease (COPD). Wellinks offers a smart strap that enables patients, parents, and healthcare providers to monitor the duration and fit of scoliosis braces, thereby preventing the need for surgeries. The technology provides real-time data and feedback, empowering users to make informed decisions about their treatment. Additionally, Wellinks focuses on individualized care for COPD patients, offering digital health systems that support remote monitoring and management of respiratory conditions, enhancing patient engagement and health outcomes. The company operates as a subsidiary of Convexity Scientific Inc.

Budderfly, Inc. is a company based in Shelton, Connecticut, that specializes in energy management systems designed to optimize energy consumption for various facilities, including office buildings, retail stores, schools, healthcare facilities, and restaurants. Established in 2007, Budderfly offers a comprehensive Energy-as-a-Service model that incorporates proprietary energy intelligence software and a range of energy-efficient technology upgrades. This includes the deployment of IoT devices, LED lighting, HVAC controls, and refrigeration systems to monitor and manage energy usage effectively. By implementing these solutions at no upfront cost to clients, Budderfly not only delivers immediate energy expense savings but also ensures ongoing maintenance and updates to prevent obsolescence in energy infrastructure. The company's approach contributes to significant reductions in carbon footprints while enhancing the overall efficiency of energy consumption in client facilities.

Inbox Health Corp. is a digital healthcare company that focuses on improving patient communication regarding medical billing in the United States. Established in 2014 and based in New Haven, Connecticut, the company offers a platform that automates the patient communication process through bi-directional correspondence and advanced technologies such as machine learning and artificial intelligence. This platform helps patients better understand their medical bills and provides various payment options. By analyzing data from its customer base, Inbox Health enables medical billers to customize the billing and communication experience for each patient, thereby enhancing collections and overall patient satisfaction. The company's mission is to reduce administrative inefficiencies in healthcare by streamlining the billing and payment processes for patients.

Cybrexa, Inc. is focused on developing innovative DNA repair inhibitors aimed at enhancing cancer therapeutics through the use of peptide-based technology that directly targets the tumor microenvironment. Established in 2016 and based in New Haven, Connecticut, the company leverages a unique tumor-localizing peptide technology developed at Yale University. This approach aims to revolutionize drug delivery by improving the therapeutic index, allowing for safer administration of higher doses of chemotherapy and radiotherapy. Cybrexa's pipeline includes a collection of small molecule inhibitors that can be combined with existing anticancer agents, thereby expanding treatment options for patients and addressing significant unmet medical needs in oncology. Through its research, Cybrexa seeks to improve patient outcomes and redefine the landscape of cancer treatment.

Payveris, LLC operates a cloud-based digital payment and money transfer platform aimed at serving financial institutions and their partners. Founded in 2011 and headquartered in Cromwell, Connecticut, Payveris provides a range of services including consumer and business bill payment solutions, account-to-account external transfers, and person-to-person payment capabilities. Customers can easily send money from their bank or credit union accounts to others via the web, smartphones, or tablets. The platform also features PayWatch, an integrated fraud prevention solution that monitors transactions across various payment types, and PayItNow, which connects financial institutions, merchants, and consumers in the payment process. Payveris has established strategic partnerships with Kony and Corelation to enhance its offerings.

IsoPlexis is a life science technology company based in Branford, Connecticut, founded in 2013. It focuses on developing a single-cell detection system that identifies patient immune responses at the single-cell level. This innovative platform enables the assessment of therapeutic safety and efficacy, as well as the monitoring of disease progression. IsoPlexis specializes in cell-based proteomic systems and biomarkers, providing insights into functional protein biology and cellular signaling networks with high resolution. By offering these capabilities, the company aids in predicting patient responses to novel immunotherapies and cellular therapies, ultimately enhancing therapeutic development and informing clinical decisions.

Allyx Therapeutics, founded in 2018 and based in Durham, Connecticut, is a clinical-stage biotechnology company focused on developing disease-modifying treatments for Alzheimer's Disease. The company’s primary product is an orally bioavailable small molecule that functions as a silent allosteric modulator of mGluR5. This innovative drug aims to reverse neurodegeneration and offers a potential approach to preserve cognitive function in patients with Alzheimer's. By targeting the underlying mechanisms of the disease, Allyx Therapeutics strives to provide effective therapeutic solutions for those affected by neurodegenerative disorders.

Torigen Pharmaceuticals is dedicated to advancing cancer care for companion animals through innovative treatment options. Founded in 2013 and based in Farmington, Connecticut, the company focuses on developing immunotherapy solutions, particularly an experimental autologous cancer vaccine. This vaccine aims to activate the immune system to target specific tumor-associated antigens present on cancer cells, allowing for more effective detection and treatment of tumors. By providing alternatives to traditional, invasive methods such as surgeries and chemotherapy, Torigen seeks to improve the quality of life for pets facing cancer. The company builds on years of scientific research and is committed to pushing the boundaries of veterinary oncology.

Phlatbed Inc. is a consumer logistics company that developed an on-demand moving application designed to connect users with local drivers for transporting items. Founded in 2016 and based in Norwalk, Connecticut, the platform allows customers to place real-time requests and select from multiple drivers who can assist with moving, packing, loading, and junk removal. By centralizing moving requests based on geographic preferences and pricing, Phlatbed enhances accessibility and efficiency in the logistics sector. Payments are processed automatically through various methods, including credit cards and PayPal, upon completion of the service. The platform operates across the United States and Canada, with plans to expand into the United Kingdom. Additionally, Phlatbed maintains an active blog and social media presence to engage with the community and provide updates on its services.

Bactana Corporation focuses on researching and developing nutritional products aimed at enhancing microbiome health in livestock and pets. The company has created a product platform called FPS-4, which leverages the beneficial interaction between an animal’s immune system and metabolism to boost productivity while ensuring good health. Bactana's approach includes identifying and isolating beneficial molecules from anaerobic bacteria found in the animal microbiome. The company also targets metabolic conditions and digestive disorders in pets, aiming to develop therapies for issues such as prediabetes and diabetes. Additionally, Bactana is committed to creating sustainable products that reduce the reliance on antibiotics and conserve natural resources in livestock production. Founded in 2016 and headquartered in Farmington, Connecticut, Bactana serves cattle farmers primarily in Connecticut and New York.

Source Defense Ltd. specializes in website security software aimed at preventing attacks originating from third-party sources. Established in 2014 and headquartered in Rosh-ha’ayin, Israel, with additional offices in Beer-Sheva and Stamford, Connecticut, the company offers a real-time Software-as-a-Service platform. This platform empowers site owners to set and enforce permissions, receive real-time alerts, and monitor the behavior of third-party vendors on their sites. Source Defense provides tailored solutions for various sectors, including financial institutions, insurance companies, e-commerce, and content publishers. By focusing on prevention rather than detection, Source Defense helps organizations eliminate security concerns associated with third-party integrations, ultimately allowing them to concentrate on enhancing revenue opportunities while ensuring the safety and performance of their websites.

Inbox Health Corp. is a digital healthcare company that focuses on improving patient communication regarding medical billing in the United States. Established in 2014 and based in New Haven, Connecticut, the company offers a platform that automates the patient communication process through bi-directional correspondence and advanced technologies such as machine learning and artificial intelligence. This platform helps patients better understand their medical bills and provides various payment options. By analyzing data from its customer base, Inbox Health enables medical billers to customize the billing and communication experience for each patient, thereby enhancing collections and overall patient satisfaction. The company's mission is to reduce administrative inefficiencies in healthcare by streamlining the billing and payment processes for patients.

In the Farmington, Connecticut area, Tunxis Community College has academic, workforce training, and personal enrichment courses for students with all sorts of different interests that can earn you an associate’s degree or certificate. Among the many majors to choose from are programs such as Allied Health, Graphic Design, Visual Fine Arts, Business Office Technology, Computer Information Systems, Criminal Justice, Drug and Alcohol Recovery Counselor, Early Childhood Education, Engineering Science and Technology Studies, and New Media Communication, as well as many more. Counselors in the financial aid office can point you toward programs that will help you earn loans, grants, scholarships, veteran’s benefits, and more if you qualify. These financial aid options can help you pay for tuition and other expenses. Student life at TCC includes a student lounge, The Cyber Café, and the Barnes-Franklin Gallery, which is filled with student, community, and professional art. Academic advising is available for any student who needs help. The career center can help students find employment. Other student resources includes child care, health care, media center, and student activities.

Phlatbed Inc. is a consumer logistics company that developed an on-demand moving application designed to connect users with local drivers for transporting items. Founded in 2016 and based in Norwalk, Connecticut, the platform allows customers to place real-time requests and select from multiple drivers who can assist with moving, packing, loading, and junk removal. By centralizing moving requests based on geographic preferences and pricing, Phlatbed enhances accessibility and efficiency in the logistics sector. Payments are processed automatically through various methods, including credit cards and PayPal, upon completion of the service. The platform operates across the United States and Canada, with plans to expand into the United Kingdom. Additionally, Phlatbed maintains an active blog and social media presence to engage with the community and provide updates on its services.

ReNetX Bio, Inc. is a biotechnology company focused on developing therapeutics for injuries and damage to the central nervous system (CNS). Its primary product, Nogo Trap, is a decoy receptor that binds to growth inhibitors, facilitating the natural growth of nerve fibers and promoting processes such as axonal regeneration, axonal sprouting, and synaptic plasticity. The company's treatments address various CNS conditions, including spinal cord injury, stroke recovery, and glaucoma. Additionally, ReNetX Bio is involved in developing disease-modifying therapeutics aimed at conditions like Alzheimer's disease, utilizing small molecule oral compounds that inhibit the binding of β-amyloid oligomers in the brain. Founded in 2009 and based in New Haven, Connecticut, the company was previously known as Axerion Therapeutics, Inc. before rebranding in July 2017.

The vision of OncoSynergy, a UCSF spin-out, is to radically improve outcomes for patients with unmet needs in oncology with Resistance Mechanism Inhibitors (RMIs). This new class of therapeutics simultaneously targets multiple hallmarks of cancer progression and have demonstrated dramatic preclinical efficacy as monotherapy and in strategic combinations. It was founded in 2011 and is headquartered in Greenwich, Connecticut.

Rallybio is a clinical-stage biopharmaceutical company focused on developing transformative therapies for patients with severe and rare disorders. Founded in 2018 and based in New Haven, Connecticut, the company is advancing its lead product candidate, RLYB211, which aims to prevent fetal and neonatal alloimmune thrombocytopenia (FNAIT), a serious condition that can lead to uncontrolled bleeding in fetuses and newborns. Rallybio's portfolio includes a range of promising product candidates targeting rare diseases across various therapeutic areas, including hematology, immuno-inflammation, maternal-fetal health, and metabolic disorders. The company's efforts are supported by a team of experienced professionals with extensive expertise in biopharma research and development.

FallCall Solutions, LLC specializes in developing fall detection and telemonitoring applications aimed at enhancing the safety and communication between the elderly and their caregivers. Founded in 2015 and based in Trumbull, Connecticut, the company's flagship product, FallCall Now, is designed to differentiate between low and high mechanism falls and can alert family members and emergency services when a fall occurs. Additionally, the ElderCheck Now application facilitates communication between the geriatric population and their caregivers, promoting independence for seniors while providing peace of mind for caregivers. By utilizing widely adopted mobile platforms, FallCall Solutions focuses on creating user-friendly software that caters to the specific needs of its consumers, enabling elders to maintain active and independent lifestyles while ensuring they have access to necessary support.

Biorez, Inc. is a medical device company specializing in the development of bioresorbable scaffold implants aimed at regenerating functional tissue in vivo. Founded in 2008 and based in New Haven, Connecticut, Biorez offers innovative products such as an off-the-shelf implant for anterior cruciate ligament (ACL) reconstruction, which eliminates the need for harvesting donor tissue and serves as a superior alternative to cadaver-based materials. The company's technology utilizes a degradable polymer, specifically PLLA, to create implants that stabilize surgical repairs and facilitate the body's natural tissue regeneration, thereby enhancing musculoskeletal outcomes. Among its product lineup is the L-C Ligament® and the biorez GRAFT™, an FDA-cleared device designed for soft tissue augmentation of the rotator cuff. By leveraging this technology, Biorez aims to accelerate patient recovery and improve surgical outcomes in orthopedic procedures.

LambdaVision, Incorporated is dedicated to designing and developing a protein-based artificial retina with the goal of restoring vision for individuals suffering from advanced retinal degenerative diseases, such as retinitis pigmentosa and age-related macular degeneration. Founded in 2009 and based in Farmington, Connecticut, the company is focused on commercializing a retinal implant that employs a light-activated protein, bacteriorhodopsin, to stimulate the retinas of patients experiencing impaired vision or significant sight loss. This innovative technology aims to enhance the quality of life for millions affected by these conditions.

Edge2Web, Inc. specializes in providing cloud-based visual tools that empower industrial application builders to quickly develop, assemble, and deploy various IIoT-style applications. Founded in 2016 and headquartered in Woodbury, Connecticut, the company offers Edge2Web Director, which enables industrial domain experts to create sophisticated dashboards and mash-up applications. Its low-code solutions facilitate the development of interactive machine and plant monitors, device-connected diagnostic guides, and manufacturing process dashboards. By integrating data and applications across operational technology (OT), information technology (IT), and enterprise cloud environments, Edge2Web's tools minimize IT disruption and allow for rapid scaling to meet diverse industrial needs. This approach helps equipment manufacturers, systems integrators, and industrial experts deliver actionable insights to end users, ultimately enhancing operational performance.

IsoPlexis is a life science technology company based in Branford, Connecticut, founded in 2013. It focuses on developing a single-cell detection system that identifies patient immune responses at the single-cell level. This innovative platform enables the assessment of therapeutic safety and efficacy, as well as the monitoring of disease progression. IsoPlexis specializes in cell-based proteomic systems and biomarkers, providing insights into functional protein biology and cellular signaling networks with high resolution. By offering these capabilities, the company aids in predicting patient responses to novel immunotherapies and cellular therapies, ultimately enhancing therapeutic development and informing clinical decisions.

The Big Willow, Inc. is a company that specializes in designing and developing platforms for marketing teams, focusing on uncovering buyer intent through advanced data processing. By indexing content consumption across web sessions, The Big Willow connects off-site behaviors to activity data from various marketing and customer relationship management tools. Its product offerings include a B2B-centric programmatic advertising platform, account-based marketing solutions, and various Adtech and Paid Media Solutions aimed at pre-targeted advertising and custom content syndication for prospects demonstrating buyer intent. Additionally, the company provides Martech Solutions to support account-based marketing initiatives and Sales Enablement Solutions to enhance deal flow and revenue generation from qualified leads. Founded in 2013 and headquartered in Wilton, Connecticut, The Big Willow operates as a subsidiary of Aberdeen Group LLC.

Trinity Mobile Networks, Inc. specializes in developing advanced networking solutions aimed at enhancing mobile connectivity. The company has created a multi-network overlay SDN platform, known as TrinitySDN, which integrates cellular, Wi-Fi, and mesh connections specifically designed for smartphones and other mobile devices with multiple interfaces. This platform empowers network operators with tools for unified monitoring across various connection types, enabling features such as software-defined multipath transmissions, seamless network handoffs, and real-time diagnostics for network performance. Additionally, Trinity Mobile Networks has developed wireless mesh networking technologies and a corresponding Android application that allows users to access high-quality, affordable mesh connections, thereby reducing dependence on costly cellular services. Founded in 2014 and headquartered in New Haven, Connecticut, the company is committed to improving data speeds and overall network bandwidth while optimizing traffic across existing infrastructure.

Bactana Corporation focuses on researching and developing nutritional products aimed at enhancing microbiome health in livestock and pets. The company has created a product platform called FPS-4, which leverages the beneficial interaction between an animal’s immune system and metabolism to boost productivity while ensuring good health. Bactana's approach includes identifying and isolating beneficial molecules from anaerobic bacteria found in the animal microbiome. The company also targets metabolic conditions and digestive disorders in pets, aiming to develop therapies for issues such as prediabetes and diabetes. Additionally, Bactana is committed to creating sustainable products that reduce the reliance on antibiotics and conserve natural resources in livestock production. Founded in 2016 and headquartered in Farmington, Connecticut, Bactana serves cattle farmers primarily in Connecticut and New York.

Inbox Health Corp. is a digital healthcare company that focuses on improving patient communication regarding medical billing in the United States. Established in 2014 and based in New Haven, Connecticut, the company offers a platform that automates the patient communication process through bi-directional correspondence and advanced technologies such as machine learning and artificial intelligence. This platform helps patients better understand their medical bills and provides various payment options. By analyzing data from its customer base, Inbox Health enables medical billers to customize the billing and communication experience for each patient, thereby enhancing collections and overall patient satisfaction. The company's mission is to reduce administrative inefficiencies in healthcare by streamlining the billing and payment processes for patients.

SmartPay Solutions LLC, founded in 2010 and based in Southington, Connecticut, specializes in providing a cloud-based software solution for pay-as-you-go workers’ compensation plans. The SmartPay platform is designed for insurance carriers, independent agents, and payroll providers, offering a flexible and user-friendly system that enables immediate access to essential services. The company's technology aims to streamline the workers' compensation process, ensuring that it meets the diverse needs of its clients. By leveraging innovative software, SmartPay Solutions enhances the efficiency and effectiveness of pay-as-you-go workers’ compensation administration.

Payveris, LLC operates a cloud-based digital payment and money transfer platform aimed at serving financial institutions and their partners. Founded in 2011 and headquartered in Cromwell, Connecticut, Payveris provides a range of services including consumer and business bill payment solutions, account-to-account external transfers, and person-to-person payment capabilities. Customers can easily send money from their bank or credit union accounts to others via the web, smartphones, or tablets. The platform also features PayWatch, an integrated fraud prevention solution that monitors transactions across various payment types, and PayItNow, which connects financial institutions, merchants, and consumers in the payment process. Payveris has established strategic partnerships with Kony and Corelation to enhance its offerings.

Wellinks, Inc., based in New Haven, Connecticut, specializes in wearable health technology aimed at improving clinical outcomes. Initially founded as 109 Design LLC in 2014, the company develops innovative devices for managing conditions such as scoliosis and chronic obstructive pulmonary disease (COPD). Wellinks offers a smart strap that enables patients, parents, and healthcare providers to monitor the duration and fit of scoliosis braces, thereby preventing the need for surgeries. The technology provides real-time data and feedback, empowering users to make informed decisions about their treatment. Additionally, Wellinks focuses on individualized care for COPD patients, offering digital health systems that support remote monitoring and management of respiratory conditions, enhancing patient engagement and health outcomes. The company operates as a subsidiary of Convexity Scientific Inc.

ShopLandia, Inc. is a company based in Stamford, Connecticut, founded in 2014. It specializes in a mobile application that provides a unique shoppable video platform, allowing users to create, edit, and stream product videos for online sales. The platform features end-to-end SaaS capabilities, enabling customization of videos with music, filters, and special effects. By facilitating both recorded and live video, ShopLandia supports peer-to-peer buying and selling, empowering users to showcase their products effectively and efficiently.

Arccos Golf, LLC, founded in 2012 and headquartered in Stamford, Connecticut, specializes in developing and marketing sensor-based products and mobile applications aimed at enhancing golfers' performance. The company's flagship Arccos Caddie platform offers features such as automatic shot tracking, smart distance club averages, an AI-powered GPS rangefinder, advanced analytics, and personalized caddie advice. By utilizing sensors attached to golf clubs, along with a mobile application and web dashboard, Arccos Golf enables golfers to monitor key performance metrics, including clubhead speed and face angle, facilitating data-driven insights for improvement. This innovative approach caters to golfers of all skill levels, helping them make informed decisions on the course and ultimately lower their scores.

Chiefofstaff.com LLC operates a cloud-based strategic plan management platform designed to assist organizations in measuring, monitoring, and managing the implementation of their strategic plans. Based in Hartford, Connecticut, with additional offices in major cities worldwide, the platform provides real-time feedback and insights for executives, particularly CEOs, enabling them to make informed decisions by offering a comprehensive overview of plan progress. It facilitates communication between top management and front-line managers, allowing for effective execution and alignment of strategic initiatives across various departments. The platform is intuitive, customizable, and scalable, catering to the needs of complex organizations. Clients include notable organizations such as New York Life Mexico, Zodiac Aerospace, and Deloitte. Founded by Robert Epner, the platform is designed to streamline strategy execution across multiple countries and businesses, enhancing operational efficiency and transparency.

SeeClickFix, Inc. is a communications platform designed to facilitate the reporting of non-emergency issues by citizens and enable governments to effectively track, manage, and respond to these reports. The company provides a suite of tools aimed at enhancing transparency, collaboration, and civic engagement within communities. Key offerings include Request Management for efficient data collection and communication, Work Management for managing assignments and internal communication, and Citizen Engagement tools that keep residents informed. Additionally, SeeClickFix offers data analytics solutions to measure success and provide insights for decision-making. The platform is designed to accommodate various community sizes and budgets, thereby empowering citizens and government entities to work together toward improving neighborhoods. Founded in 2007 and based in New Haven, Connecticut, SeeClickFix operates as a subsidiary of CivicPlus, LLC.

NorthPage provides a cloud-based digital marketing optimization platform that enables frictionless performance benchmarking, competitive analysis, and best-practice guidance for enterprise marketing organizations. Its solutions enable optimization of Websites, e-commerce sites, mobile marketing, social media, search engine marketing, content marketing, and e-retail programs. The company serves retail, financial services, consumer product, pharmaceutical, and technology companies. NorthPage Inc. was founded in 2007 and is based in Southbury, Connecticut.

Device42, Inc. specializes in providing software solutions for system, network, and data center engineers, as well as IT managers. Founded in 2010 and headquartered in West Haven, Connecticut, with an additional office in Boston, the company offers tools for patch panel cable management, IT inventory management, data center power management, and IP address tracking. Its platform includes features such as Configuration Management Database (CMDB), Application Dependency Mapping (ADM), and a Data Center Infrastructure Management (DCIM) Software Marketplace, which helps organizations maintain an accurate inventory of both IP-based and non-IP assets. Device42's software supports various documentation needs for physical, virtual, and clustered devices, facilitating effective management of hybrid IT environments, cloud migrations, and compliance with internal and external requirements.

eBrevia, Inc. specializes in artificial intelligence-driven software designed for legal applications, including due diligence, contract management, lease abstraction, and document drafting. The company's offerings include the Diligence Accelerator, which helps attorneys efficiently navigate the due diligence process by extracting relevant content from legal documents and populating summary templates. Additionally, the eBrevia Contract Analyzer aids organizations in storing, retrieving, and analyzing contracts, while the Lease Abstractor streamlines the lease review process by highlighting pertinent information. eBrevia Bespoke further enhances this by identifying custom terms within legal documents. Founded in 2011 and headquartered in Stamford, Connecticut, with additional offices in San Francisco and New York, eBrevia serves law firms and corporate legal departments. The company has received recognition for its innovative technology, including awards from the Connecticut Technology Council and accolades at national competitions. eBrevia operates as a subsidiary of Donnelley Financial Solutions, Inc.

Fitscript LLC is a Connecticut-based company that specializes in providing digital exercise programs aimed at diabetes prevention and weight management. Through its application, GlucoseZone, the company offers a range of online videos, including total body workouts, chair exercises, core training, and yoga specifically designed for individuals managing diabetes. The platform tailors exercise guidance based on users' real-time glucose levels, diabetes conditions, and fitness goals, catering to both type 1 and type 2 diabetes. For type 1 diabetes, it focuses on stabilizing glucose fluctuations, while for type 2 diabetes, it emphasizes weight loss through structured exercise programs. Originally founded as Exerscrip LLC in 2010, the company rebranded to Fitscript in April 2016 and was launched by Charles O’Connell.

Wellinks, Inc., based in New Haven, Connecticut, specializes in wearable health technology aimed at improving clinical outcomes. Initially founded as 109 Design LLC in 2014, the company develops innovative devices for managing conditions such as scoliosis and chronic obstructive pulmonary disease (COPD). Wellinks offers a smart strap that enables patients, parents, and healthcare providers to monitor the duration and fit of scoliosis braces, thereby preventing the need for surgeries. The technology provides real-time data and feedback, empowering users to make informed decisions about their treatment. Additionally, Wellinks focuses on individualized care for COPD patients, offering digital health systems that support remote monitoring and management of respiratory conditions, enhancing patient engagement and health outcomes. The company operates as a subsidiary of Convexity Scientific Inc.

GestVision, Inc. develops a diagnostic test aimed at detecting preeclampsia in pregnant women, a condition marked by high blood pressure and protein in the urine. The company's primary offering is the Congo Red Dot (CRD) urine test, designed to confirm or rule out the presence of this serious pregnancy-related condition. Established in 2014 and based in Groton, Connecticut, GestVision focuses on providing point-of-care diagnostic solutions that improve maternal and fetal health outcomes. Preeclampsia poses significant risks, including seizures and mortality, making effective detection and management essential. The company seeks to enhance the safety of pregnancies by delivering innovative diagnostic tools that support healthcare providers in identifying and addressing this critical health issue.

ZetrOZ, LLC specializes in the development and manufacturing of advanced ultrasound systems aimed at therapeutic and diagnostic applications. The company offers a range of products, including UltrOZ Elite therapeutic systems designed for both human and veterinary use, as well as high-intensity focused ultrasound systems applicable in biomedical research and industrial processes. ZetrOZ also provides various ultrasound transducers suited for therapeutic uses such as physiotherapy, drug delivery, and wound care, alongside applications in industrial monitoring and aquatic deterrents. The company has introduced innovative generator technology, enhancing the efficiency and portability of ultrasound systems, making them more economically viable. Founded in 2009 and based in Trumbull, Connecticut, ZetrOZ focuses on non-invasive medical devices that aim to alleviate chronic musculoskeletal pain through advanced treatment monitoring and user-friendly design features.

IsoPlexis is a life science technology company based in Branford, Connecticut, founded in 2013. It focuses on developing a single-cell detection system that identifies patient immune responses at the single-cell level. This innovative platform enables the assessment of therapeutic safety and efficacy, as well as the monitoring of disease progression. IsoPlexis specializes in cell-based proteomic systems and biomarkers, providing insights into functional protein biology and cellular signaling networks with high resolution. By offering these capabilities, the company aids in predicting patient responses to novel immunotherapies and cellular therapies, ultimately enhancing therapeutic development and informing clinical decisions.

SmartPay Solutions LLC, founded in 2010 and based in Southington, Connecticut, specializes in providing a cloud-based software solution for pay-as-you-go workers’ compensation plans. The SmartPay platform is designed for insurance carriers, independent agents, and payroll providers, offering a flexible and user-friendly system that enables immediate access to essential services. The company's technology aims to streamline the workers' compensation process, ensuring that it meets the diverse needs of its clients. By leveraging innovative software, SmartPay Solutions enhances the efficiency and effectiveness of pay-as-you-go workers’ compensation administration.

P2 Science a venture-backed, renewable specialty chemicals company, co-founded by Yale scientists, a chemical industry CEO and Elm Street Ventures, an early-stage venture fund. P2 Science has developed a unique process technology for converting renewable feedstocks—including vegetable oils—into high-value, specialty chemicals. These include flavor, fragrance and cosmetics ingredients. Many of their products are today available only from petrochemical sources. Among the first products to be produced by P2 are vegetable-derived, cost-effective versions of current petrochemical fragrance ingredients. Major users and formulators of specialty chemicals have a strong interest in substituting renewable for petrochemical ingredients. Patrick Foley, a Yale graduate of the PhD program in Environmental Engineering, is P2′s Chief Scientific Officer. Neil Burns, an executive with 20+ years experience in the specialty chemical industry, is the company’s CEO. P2 has a laboratory in New Haven, CT to support this technology’s development and commercialization, as well as partnerships with major companies at a number of points along the supply chain.

Avitus Orthopaedics is a medical device company developing novel instruments for minimally invasive surgery. Its novel instruments include surgical orthopedic technologies that improve clinical outcomes and develop a superior method for bone graft harvesting. It brings the technical and clinical skills and experiences necessary to develop the technology. It was founded in 2011 and headquartered in Farmington, Connecticut.

GlyGenix Therapeutics, Inc. develops therapeutic products for the treatment of cure metabolic disorders. The company manufactures and delivers genes to cure GSD1a. It has partnerships with National Institutes of Health, Duke University, University of Florida, and Royal Philips Electronics. GlyGenix Therapeutics, Inc. was founded in 2006 and is based in Woodbridge, Connecticut.

Cashpath Financial LLC, established in 2011 and located in Stamford, Connecticut, specializes in cash-flow management through its innovative mobile application. This app assists users in predicting their future cash flow, providing insights into daily, weekly, and monthly spending limits. By offering actionable guidance on saving and spending, Cashpath aims to foster financial success and help users manage their finances more effectively. The company is currently preparing to launch a beta version of its application, which is designed to enhance users' financial planning and promote positive cash flow.

Eli Nutrition, Inc. develops an antacid called Tummyzen, which is a zinc-based over-the-counter acid reducer. The company was incorporated in 2013 and is based in New Haven, Connecticut.

Biorez, Inc. is a medical device company specializing in the development of bioresorbable scaffold implants aimed at regenerating functional tissue in vivo. Founded in 2008 and based in New Haven, Connecticut, Biorez offers innovative products such as an off-the-shelf implant for anterior cruciate ligament (ACL) reconstruction, which eliminates the need for harvesting donor tissue and serves as a superior alternative to cadaver-based materials. The company's technology utilizes a degradable polymer, specifically PLLA, to create implants that stabilize surgical repairs and facilitate the body's natural tissue regeneration, thereby enhancing musculoskeletal outcomes. Among its product lineup is the L-C Ligament® and the biorez GRAFT™, an FDA-cleared device designed for soft tissue augmentation of the rotator cuff. By leveraging this technology, Biorez aims to accelerate patient recovery and improve surgical outcomes in orthopedic procedures.

Cashpath Financial LLC, established in 2011 and located in Stamford, Connecticut, specializes in cash-flow management through its innovative mobile application. This app assists users in predicting their future cash flow, providing insights into daily, weekly, and monthly spending limits. By offering actionable guidance on saving and spending, Cashpath aims to foster financial success and help users manage their finances more effectively. The company is currently preparing to launch a beta version of its application, which is designed to enhance users' financial planning and promote positive cash flow.

Precipio is a cancer diagnostics reference laboratory, delivering the latest in advanced diagnostics and personalized medicine. Our goal is to assist oncologists in providing the best care for their patients. At the intersection of academia, cancer research, and diagnostics, we connect physicians with world-renown pathologists at the Yale School of Medicine. At Precipio, our customers and their patients benefit from the most accurate, expert diagnosis.

AxioMx Inc., founded in 2012 and headquartered in Branford, Connecticut, specializes in the discovery, development, and production of recombinant antibodies. The company offers a comprehensive suite of custom antibody services, including antigen design, antibody optimization, and production tailored to the needs of researchers in diagnostics, pharmaceuticals, biotechnology, and academia. AxioMx utilizes proprietary phage display libraries and advanced affinity maturation techniques to create high-affinity antibodies that can target challenging proteins, including phosphorylated and non-immunogenic targets. Additionally, the company provides services for converting antibody formats, such as scFv to IgG, and optimizing antibody frameworks. With a focus on enhancing binding affinities and producing consistent recombinant antibodies, AxioMx supports the development of essential tools for life science research and diagnostic applications. In 2015, AxioMx became a subsidiary of Abcam Plc, further expanding its capabilities in the antibody market.

Arvinas, Inc. is a clinical-stage biopharmaceutical company based in New Haven, Connecticut, that specializes in the discovery, development, and commercialization of therapies designed to degrade disease-causing proteins. The company’s lead product candidates include ARV-110, a proteolysis-targeting chimera (PROTAC) currently in phase I clinical trials for treating metastatic castration-resistant prostate cancer, and ARV-471, which targets the estrogen receptor for patients with metastatic ER-positive/HER2-negative breast cancer. Additionally, Arvinas is developing other PROTACs aimed at degrading various androgen receptor mutations and has initiatives focused on treating neurodegenerative diseases, including tauopathies. Arvinas collaborates with major pharmaceutical companies such as Pfizer, Genentech, Roche, and Bayer to advance its innovative therapeutic approaches. Founded in 2015, Arvinas is dedicated to improving the lives of patients with debilitating and life-threatening conditions through its unique protein degradation technology.

iCleanse, a privately held company founded in 2012 by David Engelhardt, specializes in the development of multi-bay docking stations that provide secure storage, charging, and chemical-free disinfection for mobile devices such as tablets and smartphones. Headquartered in Avon, Connecticut, iCleanse's products are utilized globally across various sectors, including healthcare, retail, and food service, to enhance workflow and manage mobile devices effectively. The company's innovative docking stations are designed to eliminate pathogens, thereby fostering a healthier environment in workplaces. iCleanse focuses on delivering safety and efficiency, addressing the need for secure and hygienic handling of electronic devices in environments that require stringent sanitization practices.

American Oil Solutions (AOS) is a green technology company located in Bridgeport, Connecticut, specializing in the recycling of used hydrocarbon products, particularly tires. The company utilizes a closed-loop, pollution-free process to convert old tires into valuable products such as fuel oil, carbon char, syngas, scrap steel, and specialty chemicals. AOS aims to establish itself as a leader in the hydrocarbon product recycling market, leveraging the abundant supply of tires to create multiple revenue streams and promote sustainable practices in waste management.

Logicbroker, Inc. offers cloud and supply chain automation technology tailored for digital commerce, enabling brands, retailers, and suppliers to optimize their e-commerce operations. Founded in 2010 and based in Shelton, Connecticut, the company specializes in EDI and drop ship technology, facilitating seamless connections among brands, retailers, and their necessary systems. Logicbroker provides a comprehensive suite of tools for monitoring, reporting, and managing vendor performance, automating essential supply chain data such as inventory, shipments, and invoices. Its offerings also include the Logicbroker Commerce API, which allows clients to manage the entire order lifecycle through a single connection, along with a business rule and validation engine. The company drives substantial online sales for major retailers and boasts a network of 4,000 brand suppliers and over 140 certified retail and marketplace channels. Logicbroker's partnerships, including a strategic relationship with Ingram Micro Commerce & Lifecycle Services, further enhance its capabilities in facilitating rapid online retail growth and expanding product assortments efficiently.

P2 Science a venture-backed, renewable specialty chemicals company, co-founded by Yale scientists, a chemical industry CEO and Elm Street Ventures, an early-stage venture fund. P2 Science has developed a unique process technology for converting renewable feedstocks—including vegetable oils—into high-value, specialty chemicals. These include flavor, fragrance and cosmetics ingredients. Many of their products are today available only from petrochemical sources. Among the first products to be produced by P2 are vegetable-derived, cost-effective versions of current petrochemical fragrance ingredients. Major users and formulators of specialty chemicals have a strong interest in substituting renewable for petrochemical ingredients. Patrick Foley, a Yale graduate of the PhD program in Environmental Engineering, is P2′s Chief Scientific Officer. Neil Burns, an executive with 20+ years experience in the specialty chemical industry, is the company’s CEO. P2 has a laboratory in New Haven, CT to support this technology’s development and commercialization, as well as partnerships with major companies at a number of points along the supply chain.

eBrevia, Inc. specializes in artificial intelligence-driven software designed for legal applications, including due diligence, contract management, lease abstraction, and document drafting. The company's offerings include the Diligence Accelerator, which helps attorneys efficiently navigate the due diligence process by extracting relevant content from legal documents and populating summary templates. Additionally, the eBrevia Contract Analyzer aids organizations in storing, retrieving, and analyzing contracts, while the Lease Abstractor streamlines the lease review process by highlighting pertinent information. eBrevia Bespoke further enhances this by identifying custom terms within legal documents. Founded in 2011 and headquartered in Stamford, Connecticut, with additional offices in San Francisco and New York, eBrevia serves law firms and corporate legal departments. The company has received recognition for its innovative technology, including awards from the Connecticut Technology Council and accolades at national competitions. eBrevia operates as a subsidiary of Donnelley Financial Solutions, Inc.

Innovatient Solutions provides a patient engagement solution to the health care industry. They strive every day to enable patients to take more control of their health and to have more say in how they are cared for before, during, and after their hospital stay. It was founded in 2010 and headquartered in Farmington, Connecticut.

ZetrOZ, LLC specializes in the development and manufacturing of advanced ultrasound systems aimed at therapeutic and diagnostic applications. The company offers a range of products, including UltrOZ Elite therapeutic systems designed for both human and veterinary use, as well as high-intensity focused ultrasound systems applicable in biomedical research and industrial processes. ZetrOZ also provides various ultrasound transducers suited for therapeutic uses such as physiotherapy, drug delivery, and wound care, alongside applications in industrial monitoring and aquatic deterrents. The company has introduced innovative generator technology, enhancing the efficiency and portability of ultrasound systems, making them more economically viable. Founded in 2009 and based in Trumbull, Connecticut, ZetrOZ focuses on non-invasive medical devices that aim to alleviate chronic musculoskeletal pain through advanced treatment monitoring and user-friendly design features.

iCleanse, a privately held company founded in 2012 by David Engelhardt, specializes in the development of multi-bay docking stations that provide secure storage, charging, and chemical-free disinfection for mobile devices such as tablets and smartphones. Headquartered in Avon, Connecticut, iCleanse's products are utilized globally across various sectors, including healthcare, retail, and food service, to enhance workflow and manage mobile devices effectively. The company's innovative docking stations are designed to eliminate pathogens, thereby fostering a healthier environment in workplaces. iCleanse focuses on delivering safety and efficiency, addressing the need for secure and hygienic handling of electronic devices in environments that require stringent sanitization practices.

P2 Science a venture-backed, renewable specialty chemicals company, co-founded by Yale scientists, a chemical industry CEO and Elm Street Ventures, an early-stage venture fund. P2 Science has developed a unique process technology for converting renewable feedstocks—including vegetable oils—into high-value, specialty chemicals. These include flavor, fragrance and cosmetics ingredients. Many of their products are today available only from petrochemical sources. Among the first products to be produced by P2 are vegetable-derived, cost-effective versions of current petrochemical fragrance ingredients. Major users and formulators of specialty chemicals have a strong interest in substituting renewable for petrochemical ingredients. Patrick Foley, a Yale graduate of the PhD program in Environmental Engineering, is P2′s Chief Scientific Officer. Neil Burns, an executive with 20+ years experience in the specialty chemical industry, is the company’s CEO. P2 has a laboratory in New Haven, CT to support this technology’s development and commercialization, as well as partnerships with major companies at a number of points along the supply chain.

NorthPage provides a cloud-based digital marketing optimization platform that enables frictionless performance benchmarking, competitive analysis, and best-practice guidance for enterprise marketing organizations. Its solutions enable optimization of Websites, e-commerce sites, mobile marketing, social media, search engine marketing, content marketing, and e-retail programs. The company serves retail, financial services, consumer product, pharmaceutical, and technology companies. NorthPage Inc. was founded in 2007 and is based in Southbury, Connecticut.

eBrevia, Inc. specializes in artificial intelligence-driven software designed for legal applications, including due diligence, contract management, lease abstraction, and document drafting. The company's offerings include the Diligence Accelerator, which helps attorneys efficiently navigate the due diligence process by extracting relevant content from legal documents and populating summary templates. Additionally, the eBrevia Contract Analyzer aids organizations in storing, retrieving, and analyzing contracts, while the Lease Abstractor streamlines the lease review process by highlighting pertinent information. eBrevia Bespoke further enhances this by identifying custom terms within legal documents. Founded in 2011 and headquartered in Stamford, Connecticut, with additional offices in San Francisco and New York, eBrevia serves law firms and corporate legal departments. The company has received recognition for its innovative technology, including awards from the Connecticut Technology Council and accolades at national competitions. eBrevia operates as a subsidiary of Donnelley Financial Solutions, Inc.

Nxt-ID, Inc. specializes in technology products and services tailored for healthcare applications, with a focus on payment solutions, the Internet of Things (IoT), and security technologies. The company possesses expertise in access control, biometric identity verification, encryption, and data protection. Through its subsidiary, LogicMark LLC, Nxt-ID manufactures and distributes both monitored and non-monitored personal emergency response systems (PERS) that are marketed through dealers, distributors, and the United States Department of Veterans Affairs. Nxt-ID serves diverse sectors, including healthcare, security, financial technology, and IoT markets. Founded in 2011, the company is based in Oxford, Connecticut.

CyVek, Inc. is a biotechnology company based in Wallingford, Connecticut, established in 2008. The company specializes in developing a technology platform designed for measuring analytes in biological samples. CyVek offers an integrated test system that features a microfluidic cartridge, enabling the analysis of multiple biomarkers from minimal quantities of biological materials. This innovative approach facilitates efficient and accurate testing, supporting advancements in diagnostics and research.

Deets, Inc. is a mobile technology company based in Westport, Connecticut, founded in 2011. It specializes in a mobile communication application for Android and iPhone users, which enables the creation of organized groups, private messaging, and profile customization. The application also features a dashboard that synchronizes contacts and facilitates group conversations and collaboration. Deets aims to enhance productivity and meaningful sharing among users by providing a secure platform that mitigates the presence of fake profiles. The company launched its first product in 2012, drawing on the expertise of its founders, who previously held leadership roles in successful online companies.

Innovatient Solutions provides a patient engagement solution to the health care industry. They strive every day to enable patients to take more control of their health and to have more say in how they are cared for before, during, and after their hospital stay. It was founded in 2010 and headquartered in Farmington, Connecticut.

Lean Launch Ventures (LLV), founded in 2012 and based in Weston, Connecticut, aimed to support entrepreneurs through an accelerator curriculum grounded in the Lean LaunchPad methodology developed by Steve Blank and Bob Dorf. The firm focused on mentoring and investing in early-stage startups while also advising larger enterprises on fostering innovation. LLV served as a platform for its principals to raise and manage capital for investments in companies participating in its acceleration initiatives. However, LLV ceased operations on December 31, 2018.

NovaTract Surgical is a development stage company, intends to develop medical devices to address the rapidly growing field of Single Incision Laparoscopic Surgery (SILS) and Natural Orifice Transluminal Endoscopic Surgery (NOTES). The company was incorporated in 2010 and is based in Guilford, Connecticut.

BioRelix, Inc., a biopharmaceutical company, engages in the discovery and development of anti-biotic drug candidates for the treatment of infectious diseases in the United States. It develops a portfolio of riboswitch-based therapeutic agents to overcome the lethal and devastating causes of bacterial infections. The company was founded in 2005 and is based in New Haven, Connecticut.

Umbie Health Corporation, an East Hartford, Conn.-based that develops a Web-based and mobile practice management application for dentists.

eBrevia, Inc. specializes in artificial intelligence-driven software designed for legal applications, including due diligence, contract management, lease abstraction, and document drafting. The company's offerings include the Diligence Accelerator, which helps attorneys efficiently navigate the due diligence process by extracting relevant content from legal documents and populating summary templates. Additionally, the eBrevia Contract Analyzer aids organizations in storing, retrieving, and analyzing contracts, while the Lease Abstractor streamlines the lease review process by highlighting pertinent information. eBrevia Bespoke further enhances this by identifying custom terms within legal documents. Founded in 2011 and headquartered in Stamford, Connecticut, with additional offices in San Francisco and New York, eBrevia serves law firms and corporate legal departments. The company has received recognition for its innovative technology, including awards from the Connecticut Technology Council and accolades at national competitions. eBrevia operates as a subsidiary of Donnelley Financial Solutions, Inc.

XLerant provides business performance management software and consulting services. It offers BudgetPak, a software tool, which uses plain English prompts to guide non-financial managers in developing cost center budgets. XLerant was founded in 2004 and is based in Stamford, Connecticut.

BioRelix, Inc., a biopharmaceutical company, engages in the discovery and development of anti-biotic drug candidates for the treatment of infectious diseases in the United States. It develops a portfolio of riboswitch-based therapeutic agents to overcome the lethal and devastating causes of bacterial infections. The company was founded in 2005 and is based in New Haven, Connecticut.

C2C, LLC DBA Combat2Career® (C2C) is a Connecticut-based technology start-up venture founded in May 2011 by Meghan Brunaugh and Charlotte Creech to assist military members and veterans in the pursuit of higher education and the transition to civilian careers.

Axerion Therapeutics, Inc. is a private Connecticut-based biotechnology company focused on developing innovative therapeutics for neurological diseases and injuries with significant unmet medical need, including Alzheimer’s disease and spinal cord injury. Axerion was established in New Haven to develop and commercialize intellectual property licensed from Dr. Stephen Strittmatter’s laboratory at Yale University. Axerion’s proprietary technology platforms include blockers of ß-amyloid (Aß) oligomers binding to Prion Proteins (PrP) on the cell surface of neurons as a novel therapeutic target for Alzheimer’s disease and Nogo Receptor decoy protein for recovery of neurological function in spinal cord injury and other neurological diseases.

Thetis Pharmaceuticals LLC is a biopharmaceutical company based in Branford, Connecticut, founded in 2011. The company specializes in developing immuno-resolving therapeutic solutions aimed at treating inflammatory bowel diseases and other inflammatory conditions. Utilizing its HEALER technology platform, Thetis Pharmaceuticals focuses on the pharmacology of lipids to create new and patented small molecule drugs that promote tissue regeneration and mitigate inflammation. Their research has advanced the development of resolvins, which act as potent agonists of inflammation resolution and tissue repair. These therapies are designed to counteract excessive inflammatory responses while preserving immune function, thereby enabling healthcare professionals to better manage patients' inflammatory conditions.

NovaTract Surgical is a development stage company, intends to develop medical devices to address the rapidly growing field of Single Incision Laparoscopic Surgery (SILS) and Natural Orifice Transluminal Endoscopic Surgery (NOTES). The company was incorporated in 2010 and is based in Guilford, Connecticut.

Oxford Performance Materials employs PEKK, a thermoplastic technology platform to offer an array of business opportunities. PEKK is an ultra-high-performance thermoplastic technology platform that presents a vast array of business opportunities. Whether working to produce green energy, making planes lighter, making silicon chips faster, or making medical products that improve human health, OPM has been at the forefront of the world's deepest material challenges, helping to break down the barriers limiting human development and sustainability. The company was founded in 2000 and is headquartered in Connecticut, USA.

Sustainable Real Estate Solutions, Inc. provides on-demand energy and sustainability performance assessment and management software solutions for the commercial real estate industry. The company offers Sustainable Real Estate Manager platform, an Internet-based software as a service, which is used for monitoring building energy and water consumption and cost; automating key performance indicator analytics and reporting; tracking CO2 emissions performance; benchmarking internal and external peer buildings; comparing actual and budgeted performance; identifying no-cost/low-cost energy, water, and waste cost savings opportunities; monetizing hidden carbon assets; and facilitating compliance with energy and sustainability related disclosure, labeling, auditing, and construction regulations. Its platform enables building owners, operators, investors, lenders, tenants, and consultants to assess, benchmark, and optimize the energy and sustainability performance of individual properties and portfolios in the United States and internationally. The company is based in Monroe, Connecticut.

Zadspace Inc., a Norwalk, Connecticut is a software-as-a-service (SaaS)-based platform that enables retailers to deliver targeted advertisements on 4” x 6” color labels affixed to packages shipped to consumers, has closed a $3.2m Series B venture financing round.