VentureSouth

VentureSouth is a venture capital firm based in Greenville, South Carolina, specializing in startup and early-stage investments. The firm focuses primarily on manufacturing, logistics, and healthcare sectors, targeting opportunities in the Southeastern United States, particularly the Carolinas and surrounding areas. Since its founding, VentureSouth has developed a network of over 550 investors through various angel investment groups, making it one of the largest organizations of its kind in the country. The firm typically invests between $0.25 million and $2 million for a preferred equity stake of 15% to 35%, aiming for companies that can potentially deliver a 50% annualized rate of return within a 3-5 year timeframe. VentureSouth does not engage in common equity or debt investments, and it rarely invests in convertible debt.

Charlie Banks

Managing Director

Alex Biermann

Associate

Paul Clark

Co-Founder and Managing Director

Dawson Racek

Venture Analyst

Past deals in South Carolina

Kiyatec

Series C in 2022
Kiyatec, LLC is a biotechnology company specializing in the development of advanced 3D cell-based assays aimed at enhancing preclinical drug discovery and clinical therapy applications. Founded in 2005 and based in Greenville, South Carolina, Kiyatec employs its proprietary 3DKUBE technology platform to create functional 3D models using patients' own living tumor cells. This innovative approach allows for the evaluation of various cancer therapies, providing insights into drug toxicity and efficacy before clinical trials. The company offers a range of services, including drug response profiling, predictions of patient responses to therapies, and cell-based assays for oncologists. Additionally, Kiyatec collaborates with biopharma clients on standard and custom assays and conducts research funded by the National Cancer Institute to develop 3D cell culture models for several types of cancer, such as breast cancer, glioblastoma, and lung cancer. By modeling complex human biology and simulating in vivo conditions, Kiyatec aims to improve treatment selection for cancer patients and support the development of medical devices and therapeutic drugs.

Zylö Therapeutics

Series B in 2022
Zylo Therapeutics, Inc. is a life sciences company based in Greenville, South Carolina, specializing in a sustained-release drug delivery system. Founded in 2017, the company has developed a delivery mechanism that employs patented hydrogel-derived nanoparticles, known as Nanopodsâ„¢, to facilitate the topical administration of difficult-to-deliver therapeutic agents, including nitric oxide. This innovative system enhances drug delivery capabilities and is designed to improve the treatment of various conditions such as lupus, hair loss, joint pain, and burns. By utilizing engineered amorphous silica particles, Zylo Therapeutics aims to provide a controlled and sustained release of medications, thereby enhancing product performance and patient outcomes.

Case Status

Series A in 2022
Case Status, Inc. is a company that specializes in developing a cloud-based client engagement tool tailored for the legal services industry. Founded in 2017 and headquartered in Birmingham, Alabama, with an additional office in Charleston, South Carolina, Case Status offers an application designed to enhance lawyer-client communications. The platform addresses common challenges faced by legal professionals by providing features that allow law firms to track and measure client satisfaction, send timely updates, and facilitate communication with clients. By leveraging technology, Case Status helps legal practitioners gain real-time visibility into cases while reducing the necessity for frequent meetings.

Kiyatec

Venture Round in 2021
Kiyatec, LLC is a biotechnology company specializing in the development of advanced 3D cell-based assays aimed at enhancing preclinical drug discovery and clinical therapy applications. Founded in 2005 and based in Greenville, South Carolina, Kiyatec employs its proprietary 3DKUBE technology platform to create functional 3D models using patients' own living tumor cells. This innovative approach allows for the evaluation of various cancer therapies, providing insights into drug toxicity and efficacy before clinical trials. The company offers a range of services, including drug response profiling, predictions of patient responses to therapies, and cell-based assays for oncologists. Additionally, Kiyatec collaborates with biopharma clients on standard and custom assays and conducts research funded by the National Cancer Institute to develop 3D cell culture models for several types of cancer, such as breast cancer, glioblastoma, and lung cancer. By modeling complex human biology and simulating in vivo conditions, Kiyatec aims to improve treatment selection for cancer patients and support the development of medical devices and therapeutic drugs.

Zylö Therapeutics

Series A in 2019
Zylo Therapeutics, Inc. is a life sciences company based in Greenville, South Carolina, specializing in a sustained-release drug delivery system. Founded in 2017, the company has developed a delivery mechanism that employs patented hydrogel-derived nanoparticles, known as Nanopodsâ„¢, to facilitate the topical administration of difficult-to-deliver therapeutic agents, including nitric oxide. This innovative system enhances drug delivery capabilities and is designed to improve the treatment of various conditions such as lupus, hair loss, joint pain, and burns. By utilizing engineered amorphous silica particles, Zylo Therapeutics aims to provide a controlled and sustained release of medications, thereby enhancing product performance and patient outcomes.

Treis Blockchain

Convertible Note in 2019
Treis Blockchain, providing distributed blockchain verification services and solutions consulting. The company processes digital currency and other blockchain transactions. It data mines cryptocurrency, preventing cyberattacks in the financial and retail industries. Michael Bolick established the company in Greer, South Carolina in 2017.

Zylö Therapeutics

Seed Round in 2019
Zylo Therapeutics, Inc. is a life sciences company based in Greenville, South Carolina, specializing in a sustained-release drug delivery system. Founded in 2017, the company has developed a delivery mechanism that employs patented hydrogel-derived nanoparticles, known as Nanopodsâ„¢, to facilitate the topical administration of difficult-to-deliver therapeutic agents, including nitric oxide. This innovative system enhances drug delivery capabilities and is designed to improve the treatment of various conditions such as lupus, hair loss, joint pain, and burns. By utilizing engineered amorphous silica particles, Zylo Therapeutics aims to provide a controlled and sustained release of medications, thereby enhancing product performance and patient outcomes.

Kiyatec

Series B in 2019
Kiyatec, LLC is a biotechnology company specializing in the development of advanced 3D cell-based assays aimed at enhancing preclinical drug discovery and clinical therapy applications. Founded in 2005 and based in Greenville, South Carolina, Kiyatec employs its proprietary 3DKUBE technology platform to create functional 3D models using patients' own living tumor cells. This innovative approach allows for the evaluation of various cancer therapies, providing insights into drug toxicity and efficacy before clinical trials. The company offers a range of services, including drug response profiling, predictions of patient responses to therapies, and cell-based assays for oncologists. Additionally, Kiyatec collaborates with biopharma clients on standard and custom assays and conducts research funded by the National Cancer Institute to develop 3D cell culture models for several types of cancer, such as breast cancer, glioblastoma, and lung cancer. By modeling complex human biology and simulating in vivo conditions, Kiyatec aims to improve treatment selection for cancer patients and support the development of medical devices and therapeutic drugs.

Sharpen

Seed Round in 2018
Resiliency Technologies, Inc. operates Sharpen, a cloud-based technology and analytics platform focused on mental health and wellness. Headquartered in Spartanburg, South Carolina, the platform tracks individual and group behaviors to generate targeted recommendations through real-time analytics. Sharpen provides educational resources aimed at addressing the root causes of mental health issues such as stress, depression, and obesity. It facilitates connections among researchers, educators, and corporations to deliver evidence-based interventions, thereby supporting the prevention, early intervention, and treatment of mental health and substance use disorders. Founded in 2014, Resiliency Technologies brings over a century of expertise in the medical technology field to its mission of promoting mental well-being.

Proterra

Series G in 2018
Proterra Inc. is a manufacturer of zero-emission electric buses, primarily focused on providing sustainable transportation solutions for public and commercial transit. Founded in 2004 and headquartered in Burlingame, California, with additional offices in Greenville, South Carolina, and City of Industry, California, Proterra designs its products, including 35-foot and 40-foot electric buses, to meet the diverse needs of urban and regional transit routes. The company's Catalyst platform is noted for its modularity, allowing it to adapt to various operational demands while delivering high energy efficiency. Proterra also offers a broad range of services, including vehicle electrification solutions, fleet planning, charging infrastructure, and comprehensive vehicle maintenance programs. By facilitating the transition away from fossil fuels, Proterra aims to enhance environmental quality and reduce operational costs for fleet operators, contributing to significant reductions in greenhouse gas emissions.

Atlas Organics

Series A in 2018
Atlas Organics Inc. is a company that specializes in organics recycling services, focusing on the collection and recycling of food and yard waste. Founded in 2013 and headquartered in Spartanburg, South Carolina, the company operates in various regions, including San Antonio, Texas, and has established partnerships with municipalities to promote sustainability. Atlas Organics serves a diverse clientele, including businesses, schools, hospitals, and restaurants, by converting collected organic waste into high-quality compost products for agricultural, landscaping, and home gardening applications. The company aims to advance the "table to farm" movement, helping its customers achieve their sustainability goals while diverting compostable waste from landfills. Through its composting facilities, Atlas Organics contributes essential nutrients to soil health and supports the growth of beneficial microorganisms.

CharlestonPharma

Seed Round in 2018
CharlestonPharma, LLC, established in 2010 and headquartered in Charleston, South Carolina, specializes in developing therapeutic monoclonal antibodies targeting nucleolin, a protein overexpressed on cancer cells. The company holds worldwide licenses for producing these antibodies and using them to treat cancer patients, as well as for diagnostic applications involving nucleolin detection. Its focus is on demonstrating preclinical proof of concept for its anti-nucleolin antibodies, aiming to selectively kill cancer cells while minimizing toxicity to normal cells.

Kiyatec

Convertible Note in 2017
Kiyatec, LLC is a biotechnology company specializing in the development of advanced 3D cell-based assays aimed at enhancing preclinical drug discovery and clinical therapy applications. Founded in 2005 and based in Greenville, South Carolina, Kiyatec employs its proprietary 3DKUBE technology platform to create functional 3D models using patients' own living tumor cells. This innovative approach allows for the evaluation of various cancer therapies, providing insights into drug toxicity and efficacy before clinical trials. The company offers a range of services, including drug response profiling, predictions of patient responses to therapies, and cell-based assays for oncologists. Additionally, Kiyatec collaborates with biopharma clients on standard and custom assays and conducts research funded by the National Cancer Institute to develop 3D cell culture models for several types of cancer, such as breast cancer, glioblastoma, and lung cancer. By modeling complex human biology and simulating in vivo conditions, Kiyatec aims to improve treatment selection for cancer patients and support the development of medical devices and therapeutic drugs.

PharmRight

Convertible Note in 2017
PharmRight Corporation, founded in 2013 and based in Charleston, South Carolina, specializes in the design and development of medical devices aimed at enhancing medication adherence at home. The company is known for its innovative product, Livi, an automated pill dispenser that aids users in managing their medication schedules independently. Livi is designed to support both patients and their caregivers by simplifying the process of managing multiple medications, thus providing essential assistance for effective treatment adherence. PharmRight's focus on improving medication management reflects its commitment to enhancing health outcomes through technology.

Proterra

Series F in 2017
Proterra Inc. is a manufacturer of zero-emission electric buses, primarily focused on providing sustainable transportation solutions for public and commercial transit. Founded in 2004 and headquartered in Burlingame, California, with additional offices in Greenville, South Carolina, and City of Industry, California, Proterra designs its products, including 35-foot and 40-foot electric buses, to meet the diverse needs of urban and regional transit routes. The company's Catalyst platform is noted for its modularity, allowing it to adapt to various operational demands while delivering high energy efficiency. Proterra also offers a broad range of services, including vehicle electrification solutions, fleet planning, charging infrastructure, and comprehensive vehicle maintenance programs. By facilitating the transition away from fossil fuels, Proterra aims to enhance environmental quality and reduce operational costs for fleet operators, contributing to significant reductions in greenhouse gas emissions.

CharlestonPharma

Seed Round in 2017
CharlestonPharma, LLC, established in 2010 and headquartered in Charleston, South Carolina, specializes in developing therapeutic monoclonal antibodies targeting nucleolin, a protein overexpressed on cancer cells. The company holds worldwide licenses for producing these antibodies and using them to treat cancer patients, as well as for diagnostic applications involving nucleolin detection. Its focus is on demonstrating preclinical proof of concept for its anti-nucleolin antibodies, aiming to selectively kill cancer cells while minimizing toxicity to normal cells.

Proterra

Series E in 2017
Proterra Inc. is a manufacturer of zero-emission electric buses, primarily focused on providing sustainable transportation solutions for public and commercial transit. Founded in 2004 and headquartered in Burlingame, California, with additional offices in Greenville, South Carolina, and City of Industry, California, Proterra designs its products, including 35-foot and 40-foot electric buses, to meet the diverse needs of urban and regional transit routes. The company's Catalyst platform is noted for its modularity, allowing it to adapt to various operational demands while delivering high energy efficiency. Proterra also offers a broad range of services, including vehicle electrification solutions, fleet planning, charging infrastructure, and comprehensive vehicle maintenance programs. By facilitating the transition away from fossil fuels, Proterra aims to enhance environmental quality and reduce operational costs for fleet operators, contributing to significant reductions in greenhouse gas emissions.

Atlas Organics

Convertible Note in 2017
Atlas Organics Inc. is a company that specializes in organics recycling services, focusing on the collection and recycling of food and yard waste. Founded in 2013 and headquartered in Spartanburg, South Carolina, the company operates in various regions, including San Antonio, Texas, and has established partnerships with municipalities to promote sustainability. Atlas Organics serves a diverse clientele, including businesses, schools, hospitals, and restaurants, by converting collected organic waste into high-quality compost products for agricultural, landscaping, and home gardening applications. The company aims to advance the "table to farm" movement, helping its customers achieve their sustainability goals while diverting compostable waste from landfills. Through its composting facilities, Atlas Organics contributes essential nutrients to soil health and supports the growth of beneficial microorganisms.

PharmRight

Convertible Note in 2016
PharmRight Corporation, founded in 2013 and based in Charleston, South Carolina, specializes in the design and development of medical devices aimed at enhancing medication adherence at home. The company is known for its innovative product, Livi, an automated pill dispenser that aids users in managing their medication schedules independently. Livi is designed to support both patients and their caregivers by simplifying the process of managing multiple medications, thus providing essential assistance for effective treatment adherence. PharmRight's focus on improving medication management reflects its commitment to enhancing health outcomes through technology.

PharmRight

Convertible Note in 2016
PharmRight Corporation, founded in 2013 and based in Charleston, South Carolina, specializes in the design and development of medical devices aimed at enhancing medication adherence at home. The company is known for its innovative product, Livi, an automated pill dispenser that aids users in managing their medication schedules independently. Livi is designed to support both patients and their caregivers by simplifying the process of managing multiple medications, thus providing essential assistance for effective treatment adherence. PharmRight's focus on improving medication management reflects its commitment to enhancing health outcomes through technology.

Kiyatec

Series B in 2015
Kiyatec, LLC is a biotechnology company specializing in the development of advanced 3D cell-based assays aimed at enhancing preclinical drug discovery and clinical therapy applications. Founded in 2005 and based in Greenville, South Carolina, Kiyatec employs its proprietary 3DKUBE technology platform to create functional 3D models using patients' own living tumor cells. This innovative approach allows for the evaluation of various cancer therapies, providing insights into drug toxicity and efficacy before clinical trials. The company offers a range of services, including drug response profiling, predictions of patient responses to therapies, and cell-based assays for oncologists. Additionally, Kiyatec collaborates with biopharma clients on standard and custom assays and conducts research funded by the National Cancer Institute to develop 3D cell culture models for several types of cancer, such as breast cancer, glioblastoma, and lung cancer. By modeling complex human biology and simulating in vivo conditions, Kiyatec aims to improve treatment selection for cancer patients and support the development of medical devices and therapeutic drugs.

Servosity

Convertible Note in 2015
Servosity, Inc. is a provider of IT backup and disaster recovery services tailored for managed service providers (MSPs) and IT resellers. Founded in 2005 and headquartered in Greenville, South Carolina, the company specializes in disaster recovery solutions for various platforms, including VMware and Hyper-V, and offers a comprehensive suite of services that includes a web portal, open API, and round-the-clock support. Servosity's technology is designed to protect data across virtual, physical, and cloud environments, ensuring that businesses can maintain operational continuity during disaster recovery situations. By focusing on efficiency and reliability, Servosity enables its clients to effectively manage their data and minimize downtime.

Atlas Organics

Seed Round in 2015
Atlas Organics Inc. is a company that specializes in organics recycling services, focusing on the collection and recycling of food and yard waste. Founded in 2013 and headquartered in Spartanburg, South Carolina, the company operates in various regions, including San Antonio, Texas, and has established partnerships with municipalities to promote sustainability. Atlas Organics serves a diverse clientele, including businesses, schools, hospitals, and restaurants, by converting collected organic waste into high-quality compost products for agricultural, landscaping, and home gardening applications. The company aims to advance the "table to farm" movement, helping its customers achieve their sustainability goals while diverting compostable waste from landfills. Through its composting facilities, Atlas Organics contributes essential nutrients to soil health and supports the growth of beneficial microorganisms.

GrowJourney

Convertible Note in 2015
GrowJourney LLC, established in 2014 and headquartered in Greenville, South Carolina, specializes in selling certified organic heirloom seeds online. The company focuses on seasonal varieties and accompanies its seed offerings with comprehensive organic gardening educational resources, making the process accessible to all. Through its online platform, GrowJourney provides valuable tips, instructions, and garden planning assistance, enabling users to save on retail organic products while potentially earning returns on their gardening investments.

PharmRight

Series A in 2015
PharmRight Corporation, founded in 2013 and based in Charleston, South Carolina, specializes in the design and development of medical devices aimed at enhancing medication adherence at home. The company is known for its innovative product, Livi, an automated pill dispenser that aids users in managing their medication schedules independently. Livi is designed to support both patients and their caregivers by simplifying the process of managing multiple medications, thus providing essential assistance for effective treatment adherence. PharmRight's focus on improving medication management reflects its commitment to enhancing health outcomes through technology.

ActivEd

Seed Round in 2015
ActivEd, Inc. is an educational technology company based in Greenville, South Carolina, that specializes in interactive online lessons known as Walkabouts. Founded in 2011, ActivEd focuses on transforming fundamental concepts in math and literacy into engaging, movement-rich activities tailored for Pre-K through Second Grade students. These online adventures are designed to support teachers, schools, and parents by aligning with existing educational standards, making lesson planning more accessible and effective. Walkabouts provide a dynamic approach to learning, integrating physical activity into educational experiences, and are suitable for use in various settings, including before and after school programs, as well as elementary classrooms.

CharlestonPharma

Seed Round in 2015
CharlestonPharma, LLC, established in 2010 and headquartered in Charleston, South Carolina, specializes in developing therapeutic monoclonal antibodies targeting nucleolin, a protein overexpressed on cancer cells. The company holds worldwide licenses for producing these antibodies and using them to treat cancer patients, as well as for diagnostic applications involving nucleolin detection. Its focus is on demonstrating preclinical proof of concept for its anti-nucleolin antibodies, aiming to selectively kill cancer cells while minimizing toxicity to normal cells.

The Iron Yard

Convertible Note in 2014
The Iron Yard LLC is an accelerator based in Greenville, South Carolina, with an additional office in Las Vegas, Nevada. Founded in 2011, the company specializes in seed and startup investments in technology sectors, focusing on software and software/hardware combinations. Its investment areas include healthcare, medical devices, biotech, energy, environment, wellness apps, mobile technology, and enterprise software. The Iron Yard operates three distinct programs: edu tech, open tech, and green tech. Each program lasts three months and accommodates up to ten companies. The firm provides an initial investment of $20,000 during the program and typically selects at least two companies for further funding up to $1 million, taking a six percent equity stake. While the firm prefers teams of two or more founders, it may occasionally consider solo founders. The Iron Yard is dedicated to nurturing talented developers and startups, equipping them with essential skills for long-term success in the technology industry.

Kiyatec

Convertible Note in 2014
Kiyatec, LLC is a biotechnology company specializing in the development of advanced 3D cell-based assays aimed at enhancing preclinical drug discovery and clinical therapy applications. Founded in 2005 and based in Greenville, South Carolina, Kiyatec employs its proprietary 3DKUBE technology platform to create functional 3D models using patients' own living tumor cells. This innovative approach allows for the evaluation of various cancer therapies, providing insights into drug toxicity and efficacy before clinical trials. The company offers a range of services, including drug response profiling, predictions of patient responses to therapies, and cell-based assays for oncologists. Additionally, Kiyatec collaborates with biopharma clients on standard and custom assays and conducts research funded by the National Cancer Institute to develop 3D cell culture models for several types of cancer, such as breast cancer, glioblastoma, and lung cancer. By modeling complex human biology and simulating in vivo conditions, Kiyatec aims to improve treatment selection for cancer patients and support the development of medical devices and therapeutic drugs.

Zipit Wireless

Convertible Note in 2014
Zipit Wireless, Inc. is a technology company based in Greenville, South Carolina, specializing in critical messaging and Internet of Things (IoT) solutions. Founded in 2007, the company provides instant communication systems designed for critical situations, catering to various sectors, including healthcare, education, government, and hospitality. Its Enterprise Critical Messaging Solution enables two-way communication for organizations such as hospitals and emergency services. In addition to messaging services, Zipit Wireless offers cloud-based software and cellular services that support IoT products, including a subscription billing and activations platform for managing cellular activations and subscriptions. The company also develops network-connected devices, such as wireless trail cameras and medication adherence devices, which can be managed remotely through web portals or mobile applications. With a focus on enabling businesses to optimize their mobile operations, Zipit Wireless markets its technology solutions globally.

PharmRight

Seed Round in 2014
PharmRight Corporation, founded in 2013 and based in Charleston, South Carolina, specializes in the design and development of medical devices aimed at enhancing medication adherence at home. The company is known for its innovative product, Livi, an automated pill dispenser that aids users in managing their medication schedules independently. Livi is designed to support both patients and their caregivers by simplifying the process of managing multiple medications, thus providing essential assistance for effective treatment adherence. PharmRight's focus on improving medication management reflects its commitment to enhancing health outcomes through technology.

Kiyatec

Series A in 2014
Kiyatec, LLC is a biotechnology company specializing in the development of advanced 3D cell-based assays aimed at enhancing preclinical drug discovery and clinical therapy applications. Founded in 2005 and based in Greenville, South Carolina, Kiyatec employs its proprietary 3DKUBE technology platform to create functional 3D models using patients' own living tumor cells. This innovative approach allows for the evaluation of various cancer therapies, providing insights into drug toxicity and efficacy before clinical trials. The company offers a range of services, including drug response profiling, predictions of patient responses to therapies, and cell-based assays for oncologists. Additionally, Kiyatec collaborates with biopharma clients on standard and custom assays and conducts research funded by the National Cancer Institute to develop 3D cell culture models for several types of cancer, such as breast cancer, glioblastoma, and lung cancer. By modeling complex human biology and simulating in vivo conditions, Kiyatec aims to improve treatment selection for cancer patients and support the development of medical devices and therapeutic drugs.

The Iron Yard

Series A in 2014
The Iron Yard LLC is an accelerator based in Greenville, South Carolina, with an additional office in Las Vegas, Nevada. Founded in 2011, the company specializes in seed and startup investments in technology sectors, focusing on software and software/hardware combinations. Its investment areas include healthcare, medical devices, biotech, energy, environment, wellness apps, mobile technology, and enterprise software. The Iron Yard operates three distinct programs: edu tech, open tech, and green tech. Each program lasts three months and accommodates up to ten companies. The firm provides an initial investment of $20,000 during the program and typically selects at least two companies for further funding up to $1 million, taking a six percent equity stake. While the firm prefers teams of two or more founders, it may occasionally consider solo founders. The Iron Yard is dedicated to nurturing talented developers and startups, equipping them with essential skills for long-term success in the technology industry.

Proterra

Series C in 2013
Proterra Inc. is a manufacturer of zero-emission electric buses, primarily focused on providing sustainable transportation solutions for public and commercial transit. Founded in 2004 and headquartered in Burlingame, California, with additional offices in Greenville, South Carolina, and City of Industry, California, Proterra designs its products, including 35-foot and 40-foot electric buses, to meet the diverse needs of urban and regional transit routes. The company's Catalyst platform is noted for its modularity, allowing it to adapt to various operational demands while delivering high energy efficiency. Proterra also offers a broad range of services, including vehicle electrification solutions, fleet planning, charging infrastructure, and comprehensive vehicle maintenance programs. By facilitating the transition away from fossil fuels, Proterra aims to enhance environmental quality and reduce operational costs for fleet operators, contributing to significant reductions in greenhouse gas emissions.

Kiyatec

Convertible Note in 2013
Kiyatec, LLC is a biotechnology company specializing in the development of advanced 3D cell-based assays aimed at enhancing preclinical drug discovery and clinical therapy applications. Founded in 2005 and based in Greenville, South Carolina, Kiyatec employs its proprietary 3DKUBE technology platform to create functional 3D models using patients' own living tumor cells. This innovative approach allows for the evaluation of various cancer therapies, providing insights into drug toxicity and efficacy before clinical trials. The company offers a range of services, including drug response profiling, predictions of patient responses to therapies, and cell-based assays for oncologists. Additionally, Kiyatec collaborates with biopharma clients on standard and custom assays and conducts research funded by the National Cancer Institute to develop 3D cell culture models for several types of cancer, such as breast cancer, glioblastoma, and lung cancer. By modeling complex human biology and simulating in vivo conditions, Kiyatec aims to improve treatment selection for cancer patients and support the development of medical devices and therapeutic drugs.

Selah Genomics

Seed Round in 2013
Selah Genomics Inc. is a clinical diagnostic specialist based in Greenville, South Carolina, that delivers advanced molecular and genomic diagnostic services to healthcare providers and the pharmaceutical industry in the United States. Established in 2006 and formerly known as Lab21 Inc., the company focuses on enhancing diagnostic testing services, particularly in women's health and the management of chronic conditions. Selah Genomics specializes in personalized treatment plans for various cancer types, utilizing detailed genomic profiling derived from patient tumors. Its comprehensive service offerings include next-generation sequencing, companion diagnostics, RNA sequencing, targeted sequencing, biorepository services, quantitative PCR, bioinformatics, and nucleic acid extraction. By supporting early-stage drug development, clinical trials, and regulatory processes, Selah Genomics aims to improve patient outcomes through more personalized treatment and effective patient monitoring.

CharlestonPharma

Seed Round in 2013
CharlestonPharma, LLC, established in 2010 and headquartered in Charleston, South Carolina, specializes in developing therapeutic monoclonal antibodies targeting nucleolin, a protein overexpressed on cancer cells. The company holds worldwide licenses for producing these antibodies and using them to treat cancer patients, as well as for diagnostic applications involving nucleolin detection. Its focus is on demonstrating preclinical proof of concept for its anti-nucleolin antibodies, aiming to selectively kill cancer cells while minimizing toxicity to normal cells.

Proterra

Series B in 2012
Proterra Inc. is a manufacturer of zero-emission electric buses, primarily focused on providing sustainable transportation solutions for public and commercial transit. Founded in 2004 and headquartered in Burlingame, California, with additional offices in Greenville, South Carolina, and City of Industry, California, Proterra designs its products, including 35-foot and 40-foot electric buses, to meet the diverse needs of urban and regional transit routes. The company's Catalyst platform is noted for its modularity, allowing it to adapt to various operational demands while delivering high energy efficiency. Proterra also offers a broad range of services, including vehicle electrification solutions, fleet planning, charging infrastructure, and comprehensive vehicle maintenance programs. By facilitating the transition away from fossil fuels, Proterra aims to enhance environmental quality and reduce operational costs for fleet operators, contributing to significant reductions in greenhouse gas emissions.

RidePost

Convertible Note in 2012
RidePost, Inc. is an online community based in Greenville, South Carolina, that facilitates ride-sharing and carpooling among travelers. Founded in 2012, the company focuses on connecting individuals to share rides, thereby enhancing transportation accessibility and sustainability. RidePostU, its private network tailored for universities, addresses the transportation needs of faculty, staff, and students, streamlining logistics while reducing administrative burdens. By enabling drivers to monetize empty seats and offering travelers an affordable and social means of transportation, RidePost aims to make travel more accessible while promoting environmentally friendly practices.

Zipit Wireless

Convertible Note in 2012
Zipit Wireless, Inc. is a technology company based in Greenville, South Carolina, specializing in critical messaging and Internet of Things (IoT) solutions. Founded in 2007, the company provides instant communication systems designed for critical situations, catering to various sectors, including healthcare, education, government, and hospitality. Its Enterprise Critical Messaging Solution enables two-way communication for organizations such as hospitals and emergency services. In addition to messaging services, Zipit Wireless offers cloud-based software and cellular services that support IoT products, including a subscription billing and activations platform for managing cellular activations and subscriptions. The company also develops network-connected devices, such as wireless trail cameras and medication adherence devices, which can be managed remotely through web portals or mobile applications. With a focus on enabling businesses to optimize their mobile operations, Zipit Wireless markets its technology solutions globally.

Kiyatec

Series A in 2012
Kiyatec, LLC is a biotechnology company specializing in the development of advanced 3D cell-based assays aimed at enhancing preclinical drug discovery and clinical therapy applications. Founded in 2005 and based in Greenville, South Carolina, Kiyatec employs its proprietary 3DKUBE technology platform to create functional 3D models using patients' own living tumor cells. This innovative approach allows for the evaluation of various cancer therapies, providing insights into drug toxicity and efficacy before clinical trials. The company offers a range of services, including drug response profiling, predictions of patient responses to therapies, and cell-based assays for oncologists. Additionally, Kiyatec collaborates with biopharma clients on standard and custom assays and conducts research funded by the National Cancer Institute to develop 3D cell culture models for several types of cancer, such as breast cancer, glioblastoma, and lung cancer. By modeling complex human biology and simulating in vivo conditions, Kiyatec aims to improve treatment selection for cancer patients and support the development of medical devices and therapeutic drugs.

Zipit Wireless

Convertible Note in 2011
Zipit Wireless, Inc. is a technology company based in Greenville, South Carolina, specializing in critical messaging and Internet of Things (IoT) solutions. Founded in 2007, the company provides instant communication systems designed for critical situations, catering to various sectors, including healthcare, education, government, and hospitality. Its Enterprise Critical Messaging Solution enables two-way communication for organizations such as hospitals and emergency services. In addition to messaging services, Zipit Wireless offers cloud-based software and cellular services that support IoT products, including a subscription billing and activations platform for managing cellular activations and subscriptions. The company also develops network-connected devices, such as wireless trail cameras and medication adherence devices, which can be managed remotely through web portals or mobile applications. With a focus on enabling businesses to optimize their mobile operations, Zipit Wireless markets its technology solutions globally.

Proterra

Convertible Note in 2011
Proterra Inc. is a manufacturer of zero-emission electric buses, primarily focused on providing sustainable transportation solutions for public and commercial transit. Founded in 2004 and headquartered in Burlingame, California, with additional offices in Greenville, South Carolina, and City of Industry, California, Proterra designs its products, including 35-foot and 40-foot electric buses, to meet the diverse needs of urban and regional transit routes. The company's Catalyst platform is noted for its modularity, allowing it to adapt to various operational demands while delivering high energy efficiency. Proterra also offers a broad range of services, including vehicle electrification solutions, fleet planning, charging infrastructure, and comprehensive vehicle maintenance programs. By facilitating the transition away from fossil fuels, Proterra aims to enhance environmental quality and reduce operational costs for fleet operators, contributing to significant reductions in greenhouse gas emissions.

Zipit Wireless

Series A in 2010
Zipit Wireless, Inc. is a technology company based in Greenville, South Carolina, specializing in critical messaging and Internet of Things (IoT) solutions. Founded in 2007, the company provides instant communication systems designed for critical situations, catering to various sectors, including healthcare, education, government, and hospitality. Its Enterprise Critical Messaging Solution enables two-way communication for organizations such as hospitals and emergency services. In addition to messaging services, Zipit Wireless offers cloud-based software and cellular services that support IoT products, including a subscription billing and activations platform for managing cellular activations and subscriptions. The company also develops network-connected devices, such as wireless trail cameras and medication adherence devices, which can be managed remotely through web portals or mobile applications. With a focus on enabling businesses to optimize their mobile operations, Zipit Wireless markets its technology solutions globally.
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