VentureSouth

mPATH is a developer of a cloud-based digital healthcare platform that aims to enhance preventive care quality metrics within healthcare systems. The platform employs automation to deliver evidence-based results derived from peer-reviewed medical literature, addressing quality gaps in patient care. By providing a cost-effective alternative for healthcare organizations, mPATH facilitates improved care delivery and empowers patients to navigate their health more effectively. The company's focus on automation and evidence-based practices positions it as a valuable resource for healthcare providers seeking to enhance their operational efficiency and patient outcomes.

Yuva Biosciences is a company focused on restoring mitochondrial function to combat the effects of aging, particularly in hair and skin. It specializes in the development of cosmeceuticals and pharmaceuticals aimed at addressing issues such as aging-related hair loss, wrinkled skin, and diminished energy levels. By leveraging advancements in mitochondrial science, Yuva Biosciences creates products that aim to rejuvenate users, promoting healthier hair and skin while counteracting the visible signs of aging.

6AM City is a publishing company focused on enhancing audience participation and engagement within local communities. It operates a platform that aggregates, curates, and condenses essential local news, conversations, events, and trending topics, delivering this content through daily newsletters and social media channels. By producing brief and conversational newsletters that avoid political content, 6AM City aims to foster community involvement and dialogue. The company is dedicated to educating and activating its audience, ultimately creating a hub for local content that encourages sharing and participation, thus driving community connection and engagement.

Gradient Health is a developer of an open research platform that specializes in AI-based medical imaging diagnostics and infrastructure. The company provides a comprehensive platform that includes access to a full clinical sandbox, open-source tools, and documentation, all designed to facilitate the translation of research into a secure and interoperable clinical environment. By offering these resources, Gradient Health aims to support developers in advancing medical imaging technologies and improving diagnostic processes using artificial intelligence.

APPROVE is an internal, custom-branded lending programme that shows reasonable monthly payments at Every point of sale.

Emrgy is a technology company established in 2014 that specializes in the design and deployment of modular, scalable hydroelectric solutions. The company focuses on providing innovative hydroelectric turbines that generate electricity from slow or shallow water flows. Emrgy’s products incorporate advanced technologies, including turbines, magnetic gearboxes, and compact hydroelectric power generators, which significantly lower energy costs. These solutions enable power generation companies to effectively harness electricity from slow-moving rivers and streams, positioning Emrgy as a key player in the renewable energy sector as the industry shifts toward distributed energy sources.

Babylon Micro-Farms Inc. is a company that specializes in providing innovative indoor farming solutions, enabling clients to cultivate their own produce, including leafy greens, herbs, microgreens, and edible flowers. Founded in 2017 and based in Charlottesville, Virginia, Babylon Micro-Farms has developed a smart, scalable indoor farming platform that simplifies the growing process. Utilizing remote management technology, the company aims to create a distributed network of micro-farms across North America, making sustainable hydroponic farming more accessible. The design includes low-cost micro-farms that not only cater to individual consumers but also address food insecurity, particularly in regions such as the Middle East. By automating complex farming processes, Babylon Micro-Farms empowers communities to grow fresh produce year-round while minimizing water usage, food waste, and environmental pollutants.

Darby is a technology company that specializes in enhancing medical care delivery through innovative digital solutions. Their platform functions as a virtual vending machine for medical equipment and diagnostics, facilitating hybrid care models. This allows remote clinicians to order necessary tests and treatments directly to patients' homes, reducing the need for expensive emergency department visits. Additionally, Darby develops a medical document processing platform that assists intake staff with document review by converting PDFs and e-fax documents into structured data. This improves information exchange between clinical teams and their suppliers, ensuring accuracy and efficiency in healthcare operations.

Kiyatec, LLC is a biotechnology company specializing in the development of advanced 3D cell-based assays aimed at enhancing preclinical drug discovery and clinical therapy applications. Founded in 2005 and based in Greenville, South Carolina, Kiyatec employs its proprietary 3DKUBE technology platform to create functional 3D models using patients' own living tumor cells. This innovative approach allows for the evaluation of various cancer therapies, providing insights into drug toxicity and efficacy before clinical trials. The company offers a range of services, including drug response profiling, predictions of patient responses to therapies, and cell-based assays for oncologists. Additionally, Kiyatec collaborates with biopharma clients on standard and custom assays and conducts research funded by the National Cancer Institute to develop 3D cell culture models for several types of cancer, such as breast cancer, glioblastoma, and lung cancer. By modeling complex human biology and simulating in vivo conditions, Kiyatec aims to improve treatment selection for cancer patients and support the development of medical devices and therapeutic drugs.

Healthycell is a company dedicated to enhancing nutrient delivery for improved health. It challenges traditional supplement forms, such as pills and powders, which often result in low nutrient absorption due to their outdated delivery methods. Leveraging innovative MICROGEL technology, Healthycell's dietary supplements are designed to deliver micronutrients, including vitamins, minerals, and herbal extracts, in a form that is easily absorbed by the body. This advancement allows consumers to optimize their nutrient levels effectively, promoting overall health and enhancing performance, especially for those who prefer alternatives to traditional pill supplements. Healthycell's approach represents a significant evolution in the nutritional supplement industry by prioritizing absorption and efficacy.

Get Spiffy, Inc. is a mobile service company based in Durham, North Carolina, that specializes in on-demand car washing, detailing, nano-ceramic coating, and oil change services. Founded in 2014, the company utilizes a smartphone application that facilitates both communication and payment for its services. Get Spiffy emphasizes environmental responsibility, ensuring that all car washes are eco-friendly. Through its innovative approach, the company aims to provide convenient and efficient automotive care to customers in the Triangle area and beyond.

PunchListUSA is the first online real estate platform digitizing national home inspection data to create instant repair estimates and online service orders for homeowners, brokers, and institutional investors. The platform is powered by proprietary technology and property data to deliver home repair, renovation and lifecycle services at scale through innovative products, process automation and direct integration with industry partners. Exclusive inspection data access will power end-to-end home lifecycle services and product offerings to homeowners through the PunchListUSA marketplace in its next phase of growth.

Zylo Therapeutics, Inc. is a life sciences company based in Greenville, South Carolina, specializing in a sustained-release drug delivery system. Founded in 2017, the company has developed a delivery mechanism that employs patented hydrogel-derived nanoparticles, known as Nanopods™, to facilitate the topical administration of difficult-to-deliver therapeutic agents, including nitric oxide. This innovative system enhances drug delivery capabilities and is designed to improve the treatment of various conditions such as lupus, hair loss, joint pain, and burns. By utilizing engineered amorphous silica particles, Zylo Therapeutics aims to provide a controlled and sustained release of medications, thereby enhancing product performance and patient outcomes.

Sprockets is a technology company that specializes in AI-enabled assessment tools aimed at transforming the hiring process for hourly employees. By leveraging advanced applicant matching technology, the company evaluates potential hires based on the characteristics of a company's top-performing employees. This innovative approach utilizes AI, big data, and psycholinguistics to provide hiring managers with a quick and cost-effective way to identify the best candidates. Sprockets eliminates guesswork and reduces the frustrations often associated with hiring, ultimately aiming to decrease employee turnover and enhance organizational efficiency.

Gradient Health is a developer of an open research platform that specializes in AI-based medical imaging diagnostics and infrastructure. The company provides a comprehensive platform that includes access to a full clinical sandbox, open-source tools, and documentation, all designed to facilitate the translation of research into a secure and interoperable clinical environment. By offering these resources, Gradient Health aims to support developers in advancing medical imaging technologies and improving diagnostic processes using artificial intelligence.

Case Status, Inc. is a company that specializes in developing a cloud-based client engagement tool tailored for the legal services industry. Founded in 2017 and headquartered in Birmingham, Alabama, with an additional office in Charleston, South Carolina, Case Status offers an application designed to enhance lawyer-client communications. The platform addresses common challenges faced by legal professionals by providing features that allow law firms to track and measure client satisfaction, send timely updates, and facilitate communication with clients. By leveraging technology, Case Status helps legal practitioners gain real-time visibility into cases while reducing the necessity for frequent meetings.

Bio 54 is a company focused on developing innovative solutions for the treatment of external bleeding. It specializes in creating a drug-device combination designed to address excessive bleeding, particularly in patients who are undergoing anticoagulant or anti-platelet therapy. By delivering topical anti-coagulant drugs, Bio 54 aims to enhance patient care and improve the overall quality of life for individuals affected by bleeding complications. The company's commitment to addressing this critical medical need positions it as a key player in the healthcare market.

Coworks is a company that specializes in coworking management software, designed to facilitate the management and scaling of flexible office spaces. Founded in Stockholm in 2009, Coworks aims to empower coworking space owners and operators through innovative tools that incorporate automation, analytics, and effective communication. The platform features a range of capabilities, including member directories, event calendars, front desk check-ins, automated billing, and lead management. By focusing on creating intuitive experiences for both managers and members, Coworks seeks to optimize business operations and enhance community engagement within coworking environments. The company is committed to making coworking more accessible and efficient, positioning itself as a key player in the evolving landscape of work culture and space.

Plantd is a manufacturer of building materials specifically designed for sustainable and zero-carbon housing. The company utilizes industrial hemp and renewable grass to create products that lock away carbon absorbed from the atmosphere into the walls and floors of new homes. This approach allows customers to manage costs effectively while achieving significant carbon removal and ensuring optimal material performance. Plantd's mission is driven by a team of business owners and engineers who believe in reinventing current practices to build a prosperous future.

OneDigitalTrust is a business-to-business company that provides a software-as-a-service platform focused on estate and legacy planning optimization. The company has developed a comprehensive digital platform that enables users to document their assets and liabilities, create state-specific estate planning documents, and manage their legacy through various life stages and events. By partnering with multiple financial institutions, OneDigitalTrust distributes its platform to their customers, facilitating a business-to-business-to-consumer model. The platform not only simplifies the estate planning process but also generates valuable insights, allowing clients to offer their users effective tools to safeguard and distribute their legacies.

CureMint, Inc. is a technology company based in Durham, North Carolina, founded in 2017. It specializes in developing a cloud-based procurement software tailored for the dental industry. The CureMint platform serves as a comprehensive source-to-pay solution, streamlining the entire procurement lifecycle for dental organizations. It enhances the ordering experience for office staff while providing management tools that offer visibility and control over organizational spending. The software enables users to create and manage formularies, allowing customization of product catalogs and the establishment of automated review and approval workflows. Moreover, the platform bridges gaps between procurement and accounts payable by simplifying invoicing processes, ultimately promoting operational efficiency and informed purchasing decisions within dental practices.

Pass It Down is a digital storytelling platform designed to help users record, share, and preserve their personal and family stories through various formats, including video, audio, text, and photos. It enables individuals to capture their life narratives by responding to guided questions from oral historians using phones, tablets, or computers. The platform not only serves personal storytelling needs but also caters to businesses and cultural institutions by collecting authentic stories from customers or employees. This feature allows organizations to create engaging online and touchscreen exhibits, enhancing their connection with audiences. Pass It Down empowers users to share their stories publicly, with friends and family, or keep them as private records, fostering a meaningful way to document and celebrate personal and collective histories.

6AM City is a publishing company focused on enhancing audience participation and engagement within local communities. It operates a platform that aggregates, curates, and condenses essential local news, conversations, events, and trending topics, delivering this content through daily newsletters and social media channels. By producing brief and conversational newsletters that avoid political content, 6AM City aims to foster community involvement and dialogue. The company is dedicated to educating and activating its audience, ultimately creating a hub for local content that encourages sharing and participation, thus driving community connection and engagement.

Kiyatec, LLC is a biotechnology company specializing in the development of advanced 3D cell-based assays aimed at enhancing preclinical drug discovery and clinical therapy applications. Founded in 2005 and based in Greenville, South Carolina, Kiyatec employs its proprietary 3DKUBE technology platform to create functional 3D models using patients' own living tumor cells. This innovative approach allows for the evaluation of various cancer therapies, providing insights into drug toxicity and efficacy before clinical trials. The company offers a range of services, including drug response profiling, predictions of patient responses to therapies, and cell-based assays for oncologists. Additionally, Kiyatec collaborates with biopharma clients on standard and custom assays and conducts research funded by the National Cancer Institute to develop 3D cell culture models for several types of cancer, such as breast cancer, glioblastoma, and lung cancer. By modeling complex human biology and simulating in vivo conditions, Kiyatec aims to improve treatment selection for cancer patients and support the development of medical devices and therapeutic drugs.

Trio Labs is a digital manufacturing technology company specializing in high-volume precision metal and ceramic 3D printing. Founded in 2015 and based in Durham, North Carolina, the company aims to transform the manufacturing landscape by eliminating the costs associated with tooling while enhancing the throughput of traditional high-volume production processes. Trio Labs' innovative technology enables engineers to achieve precision comparable to existing systems, allowing for the affordable production of metals and ceramics at increased volumes and speeds.

GoPivot is an employee wellness platform that focuses on enhancing workforce health and recognition. The company offers a range of solutions that include health and wellness programs, safety initiatives, rewards and recognition systems, and employee communications. GoPivot's platform enables organizations to implement point-based rewards, allowing employees to earn points through participation in wellness activities, achieving safety milestones, and receiving recognition for their contributions. By integrating advancements in data analytics and behavioral science, GoPivot aims to optimize corporate safety, wellness, and healthcare cost containment efforts, eliminating ineffective rewards and solutions while maximizing value for its clients.

Soelect Inc. is a manufacturer based in Greensboro, North Carolina, specializing in advanced solid-state battery components. Established in 2020, the company focuses on developing innovative solutions for anode technology and solid-state electrolyte materials. Its proprietary LiX technology features a lithium metal anode designed for fast charging, enhancing the performance of advanced and solid-state batteries. Soelect's products are aimed at a diverse range of applications, including electric vehicles, portable electronics, power tools, drones, aircraft, spacecraft, and tactical defense equipment. By providing high-energy-density batteries, Soelect seeks to offer safer and more efficient alternatives to traditional lithium-ion batteries, catering to various industries and enabling the advancement of next-generation energy storage solutions.

Imagine.io is a 3D content creation platform that specializes in providing furniture and textile manufacturers with the tools to generate photo-realistic 3D imagery. The platform streamlines the image production process for various applications, including e-commerce, social media, and catalogs. It allows users to create a diverse range of visual content, such as stunning silhouette and lifestyle images, augmented reality experiences, videos, and immersive shoppable experiences, without requiring any background in three-dimensional design or engineering. By automating these processes, Imagine.io enhances the speed and flexibility of interactive 3D photography, making it accessible to a broader audience within the industry.

Redbud Labs, Inc. specializes in the development and manufacturing of microfluidic technologies and MEMS components for the life science sector. The company is recognized for its innovative MXR, the world's first fully modular microfluidic mixer, which enhances assay performance for leading biotechnology firms. Redbud Labs offers solutions that facilitate small-volume sample collection, processing, and analysis, allowing for improved mixing and expedited assay times. Their cartridge-based automated sample preparation platform simplifies lab workflows while maintaining high performance, addressing the critical needs of medical professionals in research, drug discovery, and diagnostics. Founded in 2010 and based in Chapel Hill, North Carolina, Redbud Labs builds upon cutting-edge technology derived from academic research to tackle complex microfluidic challenges in an efficient and effective manner.

Sprockets is a technology company that specializes in AI-enabled assessment tools aimed at transforming the hiring process for hourly employees. By leveraging advanced applicant matching technology, the company evaluates potential hires based on the characteristics of a company's top-performing employees. This innovative approach utilizes AI, big data, and psycholinguistics to provide hiring managers with a quick and cost-effective way to identify the best candidates. Sprockets eliminates guesswork and reduces the frustrations often associated with hiring, ultimately aiming to decrease employee turnover and enhance organizational efficiency.

Babylon Micro-Farms Inc. is a company that specializes in providing innovative indoor farming solutions, enabling clients to cultivate their own produce, including leafy greens, herbs, microgreens, and edible flowers. Founded in 2017 and based in Charlottesville, Virginia, Babylon Micro-Farms has developed a smart, scalable indoor farming platform that simplifies the growing process. Utilizing remote management technology, the company aims to create a distributed network of micro-farms across North America, making sustainable hydroponic farming more accessible. The design includes low-cost micro-farms that not only cater to individual consumers but also address food insecurity, particularly in regions such as the Middle East. By automating complex farming processes, Babylon Micro-Farms empowers communities to grow fresh produce year-round while minimizing water usage, food waste, and environmental pollutants.

Seal the Seasons, Inc. is a frozen food company based in Chapel Hill, North Carolina, that specializes in processing, freezing, marketing, and distributing locally grown fruits and vegetables. Established in 2014, the company partners with local farmers across the United States to create a sustainable supply chain that enables year-round access to seasonal produce. Its product offerings include frozen items such as blueberries, broccoli, spinach, and a Fruit Medley featuring blueberries, strawberries, and blackberries. By focusing on local sourcing, Seal the Seasons not only supports rural communities but also empowers family farmers to expand their seasonal planting. The company distributes its products to grocery stores nationwide, ensuring consumers can enjoy high-quality, locally sourced food throughout the year. Over 90% of the costs associated with their products return to the local communities, fostering economic growth and promoting access to nutritious food.

Aperiomics is a biotechnology company based in Sterling, Virginia, specializing in pathogen detection services across animal screening, agricultural testing, and human diagnostics industries. Founded in 2013, the company uses advanced genomics and informatics technologies to detect viral, bacterial, fungal, and parasitic pathogens through a single test. Aperiomics employs sequencing technologies and Bayesian statistics to analyze blood, tissue, and stool samples sent by customers. The company's unique approach, supported by the National Science Foundation, involves Deep Shotgun Metagenomic Sequencing and a comprehensive database of over 37,000 microbes. This enables medical professionals to identify infections that other tests may miss, leading to more accurate diagnoses and improved clinical outcomes for patients who have often been ill for extended periods without a clear cause.

Altis Biosystems, LLC is a biotechnology company specializing in the development of innovative stem cell technologies aimed at enhancing research in human biology. Established in 2015 and based in Chapel Hill, North Carolina, the company has created a patent-pending system known as RepliGut, which effectively recreates the human intestinal epithelium and colonic epithelium. This advanced technology enables the generation of a layer of human or animal intestinal stem and differentiated cells from both the small and large intestines. Altis Biosystems' products are primarily utilized in preclinical studies for disease modeling, precision medicine, microbiome research, and compound screening, serving the needs of pharmaceutical and biotechnology companies. By utilizing normal human intestinal tissue, the company aims to improve drug development processes while minimizing reliance on animal testing.

PunchListUSA is the first online real estate platform digitizing national home inspection data to create instant repair estimates and online service orders for homeowners, brokers, and institutional investors. The platform is powered by proprietary technology and property data to deliver home repair, renovation and lifecycle services at scale through innovative products, process automation and direct integration with industry partners. Exclusive inspection data access will power end-to-end home lifecycle services and product offerings to homeowners through the PunchListUSA marketplace in its next phase of growth.

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6AM City is a publishing company focused on enhancing audience participation and engagement within local communities. It operates a platform that aggregates, curates, and condenses essential local news, conversations, events, and trending topics, delivering this content through daily newsletters and social media channels. By producing brief and conversational newsletters that avoid political content, 6AM City aims to foster community involvement and dialogue. The company is dedicated to educating and activating its audience, ultimately creating a hub for local content that encourages sharing and participation, thus driving community connection and engagement.

Reveal Mobile, Inc. is a company that specializes in location-based marketing and analytics, catering to agencies, brands, media companies, and app publishers. Founded in 2004 and based in Raleigh, North Carolina, the company operates a platform that includes solutions such as VISIT Local, which offers foot traffic attribution and audience building, and VISIT Match, designed for instant audience scaling. Additionally, Reveal Mobile provides VISIT Data, a customizable location-data solution for enterprise applications. The platform facilitates the creation of targeted audience segments and enables clients to reach these audiences through various digital advertising channels, including social media. With a strong emphasis on privacy compliance, Reveal Mobile is a member of the Network Advertising Initiative and undergoes annual privacy certifications, ensuring that its services adhere to industry standards. The company's user-friendly interface simplifies audience analytics and post-campaign reporting, allowing clients to effectively measure the impact of their marketing efforts on foot traffic.

Get Spiffy, Inc. is a mobile service company based in Durham, North Carolina, that specializes in on-demand car washing, detailing, nano-ceramic coating, and oil change services. Founded in 2014, the company utilizes a smartphone application that facilitates both communication and payment for its services. Get Spiffy emphasizes environmental responsibility, ensuring that all car washes are eco-friendly. Through its innovative approach, the company aims to provide convenient and efficient automotive care to customers in the Triangle area and beyond.

Altis Biosystems, LLC is a biotechnology company specializing in the development of innovative stem cell technologies aimed at enhancing research in human biology. Established in 2015 and based in Chapel Hill, North Carolina, the company has created a patent-pending system known as RepliGut, which effectively recreates the human intestinal epithelium and colonic epithelium. This advanced technology enables the generation of a layer of human or animal intestinal stem and differentiated cells from both the small and large intestines. Altis Biosystems' products are primarily utilized in preclinical studies for disease modeling, precision medicine, microbiome research, and compound screening, serving the needs of pharmaceutical and biotechnology companies. By utilizing normal human intestinal tissue, the company aims to improve drug development processes while minimizing reliance on animal testing.

PunchListUSA is the first online real estate platform digitizing national home inspection data to create instant repair estimates and online service orders for homeowners, brokers, and institutional investors. The platform is powered by proprietary technology and property data to deliver home repair, renovation and lifecycle services at scale through innovative products, process automation and direct integration with industry partners. Exclusive inspection data access will power end-to-end home lifecycle services and product offerings to homeowners through the PunchListUSA marketplace in its next phase of growth.

6AM City is a publishing company focused on enhancing audience participation and engagement within local communities. It operates a platform that aggregates, curates, and condenses essential local news, conversations, events, and trending topics, delivering this content through daily newsletters and social media channels. By producing brief and conversational newsletters that avoid political content, 6AM City aims to foster community involvement and dialogue. The company is dedicated to educating and activating its audience, ultimately creating a hub for local content that encourages sharing and participation, thus driving community connection and engagement.

Zylo Therapeutics, Inc. is a life sciences company based in Greenville, South Carolina, specializing in a sustained-release drug delivery system. Founded in 2017, the company has developed a delivery mechanism that employs patented hydrogel-derived nanoparticles, known as Nanopods™, to facilitate the topical administration of difficult-to-deliver therapeutic agents, including nitric oxide. This innovative system enhances drug delivery capabilities and is designed to improve the treatment of various conditions such as lupus, hair loss, joint pain, and burns. By utilizing engineered amorphous silica particles, Zylo Therapeutics aims to provide a controlled and sustained release of medications, thereby enhancing product performance and patient outcomes.

Outdoor Access, Inc. is a company based in Richmond, Virginia, that operates an online platform designed to connect outdoor enthusiasts—such as hunters, anglers, and campers—with private landowners seeking to lease their land for recreational activities. Founded in 2016, the platform offers a marketplace where landowners can monetize their properties while providing users with diverse outdoor experiences. Outdoor Access aims to make outdoor activities more accessible and affordable, promoting ethical usage and respect for landowner rules among its members. The company also emphasizes the importance of passing outdoor traditions to younger generations by allowing children under 18 to participate for free.

Aperiomics is a biotechnology company based in Sterling, Virginia, specializing in pathogen detection services across animal screening, agricultural testing, and human diagnostics industries. Founded in 2013, the company uses advanced genomics and informatics technologies to detect viral, bacterial, fungal, and parasitic pathogens through a single test. Aperiomics employs sequencing technologies and Bayesian statistics to analyze blood, tissue, and stool samples sent by customers. The company's unique approach, supported by the National Science Foundation, involves Deep Shotgun Metagenomic Sequencing and a comprehensive database of over 37,000 microbes. This enables medical professionals to identify infections that other tests may miss, leading to more accurate diagnoses and improved clinical outcomes for patients who have often been ill for extended periods without a clear cause.

HelloPackage is a sophisticated package management system developed by Package Solutions, Inc. It is specifically designed for high-density environments, primarily targeting the 75,000 apartment communities across the United States. The platform seamlessly integrates carriers, apartment communities, retailers, and residents, significantly enhancing efficiency in last-mile logistics. Utilizing advanced machine learning and artificial intelligence, HelloPackage optimizes package density and throughput, addressing the challenges of limited space for package storage in apartment settings. In addition to residential apartments, the system is applicable in various other settings, including student housing, offices, retail spaces, condo communities, hotels, and convention centers, offering a more economical and efficient alternative to traditional locker-based package services.

Avadim Health, Inc. is a healthcare and wellness company based in Asheville, North Carolina, specializing in the development, manufacturing, and marketing of topical products aimed at improving immune health, neuromuscular health, and skin barrier health. Utilizing its proprietary Bionome Engineered Platform, the company offers a diverse range of therapeutic skincare products that address various health concerns, including pain, infections, muscle cramps, spasms, restless leg symptoms, and joint discomfort. Avadim Health serves both institutional and consumer markets, distributing its products through retail outlets such as grocery stores and pharmacies, as well as acute-care hospitals, nursing homes, and online channels. Founded in 2007 and originally known as Avadim Technologies, the company rebranded to Avadim Health in September 2018, reflecting its broader focus on health and wellness solutions.

Get Spiffy, Inc. is a mobile service company based in Durham, North Carolina, that specializes in on-demand car washing, detailing, nano-ceramic coating, and oil change services. Founded in 2014, the company utilizes a smartphone application that facilitates both communication and payment for its services. Get Spiffy emphasizes environmental responsibility, ensuring that all car washes are eco-friendly. Through its innovative approach, the company aims to provide convenient and efficient automotive care to customers in the Triangle area and beyond.

Treis Blockchain, providing distributed blockchain verification services and solutions consulting. The company processes digital currency and other blockchain transactions. It data mines cryptocurrency, preventing cyberattacks in the financial and retail industries. Michael Bolick established the company in Greer, South Carolina in 2017.

Zylo Therapeutics, Inc. is a life sciences company based in Greenville, South Carolina, specializing in a sustained-release drug delivery system. Founded in 2017, the company has developed a delivery mechanism that employs patented hydrogel-derived nanoparticles, known as Nanopods™, to facilitate the topical administration of difficult-to-deliver therapeutic agents, including nitric oxide. This innovative system enhances drug delivery capabilities and is designed to improve the treatment of various conditions such as lupus, hair loss, joint pain, and burns. By utilizing engineered amorphous silica particles, Zylo Therapeutics aims to provide a controlled and sustained release of medications, thereby enhancing product performance and patient outcomes.

A marketplace and ad placement tool that allows audience owners to monetize the value they’ve created

Kiyatec, LLC is a biotechnology company specializing in the development of advanced 3D cell-based assays aimed at enhancing preclinical drug discovery and clinical therapy applications. Founded in 2005 and based in Greenville, South Carolina, Kiyatec employs its proprietary 3DKUBE technology platform to create functional 3D models using patients' own living tumor cells. This innovative approach allows for the evaluation of various cancer therapies, providing insights into drug toxicity and efficacy before clinical trials. The company offers a range of services, including drug response profiling, predictions of patient responses to therapies, and cell-based assays for oncologists. Additionally, Kiyatec collaborates with biopharma clients on standard and custom assays and conducts research funded by the National Cancer Institute to develop 3D cell culture models for several types of cancer, such as breast cancer, glioblastoma, and lung cancer. By modeling complex human biology and simulating in vivo conditions, Kiyatec aims to improve treatment selection for cancer patients and support the development of medical devices and therapeutic drugs.

LUMINELLE is a company that specializes in developing advanced medical technology for uterine diagnostics and procedures. It has created the Luminelle DTx Hysteroscopy System, which facilitates office-based procedures, allowing physicians to accurately diagnose uterine disorders with minimal to no anesthesia. The system is designed to enhance the efficiency and cost-effectiveness of hysteroscopy and cystoscopy procedures, benefiting both medical practices and patients. By providing a convenient and reliable visual biopsy platform, LUMINELLE aims to optimize revenue for healthcare practices while improving patient care.

Vendor Registry is a cloud-based platform designed to simplify the vendor registration process for local governments and institutions. By standardizing and centralizing traditionally paper-intensive workflows, the company aims to alleviate the burdens of repetitive paperwork that both vendors and government entities often face. This streamlined approach facilitates connections between vendors and governments, enhancing compliance and fostering competitive bidding. The platform is particularly beneficial for local small businesses, as it helps them generate new revenue opportunities while enabling governments to operate more efficiently with reduced costs. Ultimately, Vendor Registry seeks to create a mutually beneficial environment that supports both vendors and purchasing departments in managing taxpayer dollars more effectively.

ThreatSwitch, Inc. is a software company based in Charlotte, North Carolina, that specializes in developing a business-to-business security compliance software platform. Founded in 2016, ThreatSwitch offers a SaaS solution tailored for organizations subject to stringent security regulations. The platform enables security professionals to efficiently manage various aspects of compliance programs, including personnel access, eligibility, investigations, and training progress. It facilitates self-reporting by employees and automates user activity tracking while allowing the creation of customized forms for data collection without compromising sensitive information. Additionally, the platform supports the management of visitor access requests, contributing to a streamlined security process. By leveraging ThreatSwitch's software, clients can achieve lower compliance costs, enhance employee engagement in security initiatives, and mitigate overall risk.

KWIPPED, Inc. is a B2B online equipment rental marketplace based in Wilmington, North Carolina, established in 2011. The company enables businesses to easily locate and rent specialized equipment from a global network of suppliers. KWIPPED's platform simplifies the sourcing process, reducing risk and ensuring quality while fostering trusted relationships between renters and suppliers. By offering a comprehensive selection of rental equipment, KWIPPED facilitates access for commercial applications, streamlining the equipment rental experience for its users.

Sprockets is a technology company that specializes in AI-enabled assessment tools aimed at transforming the hiring process for hourly employees. By leveraging advanced applicant matching technology, the company evaluates potential hires based on the characteristics of a company's top-performing employees. This innovative approach utilizes AI, big data, and psycholinguistics to provide hiring managers with a quick and cost-effective way to identify the best candidates. Sprockets eliminates guesswork and reduces the frustrations often associated with hiring, ultimately aiming to decrease employee turnover and enhance organizational efficiency.

Resiliency Technologies, Inc. operates Sharpen, a cloud-based technology and analytics platform focused on mental health and wellness. Headquartered in Spartanburg, South Carolina, the platform tracks individual and group behaviors to generate targeted recommendations through real-time analytics. Sharpen provides educational resources aimed at addressing the root causes of mental health issues such as stress, depression, and obesity. It facilitates connections among researchers, educators, and corporations to deliver evidence-based interventions, thereby supporting the prevention, early intervention, and treatment of mental health and substance use disorders. Founded in 2014, Resiliency Technologies brings over a century of expertise in the medical technology field to its mission of promoting mental well-being.

Reveal Mobile, Inc. is a company that specializes in location-based marketing and analytics, catering to agencies, brands, media companies, and app publishers. Founded in 2004 and based in Raleigh, North Carolina, the company operates a platform that includes solutions such as VISIT Local, which offers foot traffic attribution and audience building, and VISIT Match, designed for instant audience scaling. Additionally, Reveal Mobile provides VISIT Data, a customizable location-data solution for enterprise applications. The platform facilitates the creation of targeted audience segments and enables clients to reach these audiences through various digital advertising channels, including social media. With a strong emphasis on privacy compliance, Reveal Mobile is a member of the Network Advertising Initiative and undergoes annual privacy certifications, ensuring that its services adhere to industry standards. The company's user-friendly interface simplifies audience analytics and post-campaign reporting, allowing clients to effectively measure the impact of their marketing efforts on foot traffic.

ProAxion, Inc. is a Cary, North Carolina-based company that specializes in manufacturing cloud-connected sensors aimed at enhancing predictive maintenance for industrial machinery. Established in 2015, ProAxion develops a product called TACTIX, which enables remote monitoring of the health of rotating machines. Through the use of low-power sensors and advanced cloud computing technologies, the company provides solutions that improve equipment uptime and reliability while optimizing operational and maintenance costs. ProAxion's innovative approach contributes to the broader advancement of the Industrial Internet of Things, helping to prevent unexpected failures in mission-critical machines and ensuring the efficient operation of industrial facilities.

Proterra Inc. is a manufacturer of zero-emission electric buses, primarily focused on providing sustainable transportation solutions for public and commercial transit. Founded in 2004 and headquartered in Burlingame, California, with additional offices in Greenville, South Carolina, and City of Industry, California, Proterra designs its products, including 35-foot and 40-foot electric buses, to meet the diverse needs of urban and regional transit routes. The company's Catalyst platform is noted for its modularity, allowing it to adapt to various operational demands while delivering high energy efficiency. Proterra also offers a broad range of services, including vehicle electrification solutions, fleet planning, charging infrastructure, and comprehensive vehicle maintenance programs. By facilitating the transition away from fossil fuels, Proterra aims to enhance environmental quality and reduce operational costs for fleet operators, contributing to significant reductions in greenhouse gas emissions.

Emrgy is a technology company established in 2014 that specializes in the design and deployment of modular, scalable hydroelectric solutions. The company focuses on providing innovative hydroelectric turbines that generate electricity from slow or shallow water flows. Emrgy’s products incorporate advanced technologies, including turbines, magnetic gearboxes, and compact hydroelectric power generators, which significantly lower energy costs. These solutions enable power generation companies to effectively harness electricity from slow-moving rivers and streams, positioning Emrgy as a key player in the renewable energy sector as the industry shifts toward distributed energy sources.

Ecomdash is a cloud-based software company that specializes in automating backend operations for ecommerce sellers. Its platform integrates and streamlines inventory management, sales orders, product listings, and shipping processes across multiple marketplaces like Amazon and eBay, as well as ecommerce platforms such as Shopify. By utilizing Ecomdash's services, merchants can efficiently grow their sales, save time on operational tasks, and enhance customer satisfaction.

Vendor Registry is a cloud-based platform designed to simplify the vendor registration process for local governments and institutions. By standardizing and centralizing traditionally paper-intensive workflows, the company aims to alleviate the burdens of repetitive paperwork that both vendors and government entities often face. This streamlined approach facilitates connections between vendors and governments, enhancing compliance and fostering competitive bidding. The platform is particularly beneficial for local small businesses, as it helps them generate new revenue opportunities while enabling governments to operate more efficiently with reduced costs. Ultimately, Vendor Registry seeks to create a mutually beneficial environment that supports both vendors and purchasing departments in managing taxpayer dollars more effectively.

6AM City is a publishing company focused on enhancing audience participation and engagement within local communities. It operates a platform that aggregates, curates, and condenses essential local news, conversations, events, and trending topics, delivering this content through daily newsletters and social media channels. By producing brief and conversational newsletters that avoid political content, 6AM City aims to foster community involvement and dialogue. The company is dedicated to educating and activating its audience, ultimately creating a hub for local content that encourages sharing and participation, thus driving community connection and engagement.

Get Spiffy, Inc. is a mobile service company based in Durham, North Carolina, that specializes in on-demand car washing, detailing, nano-ceramic coating, and oil change services. Founded in 2014, the company utilizes a smartphone application that facilitates both communication and payment for its services. Get Spiffy emphasizes environmental responsibility, ensuring that all car washes are eco-friendly. Through its innovative approach, the company aims to provide convenient and efficient automotive care to customers in the Triangle area and beyond.

Cirtemo is a manufacturer of advanced optical filters that focus on measuring specific chemical attributes. The company's proprietary multivariate optical elements utilize microscopic sensors, significantly enhancing the sensitivity and specificity of analyte detection compared to traditional narrow band pass filter technology. This innovation allows clients to identify chemicals at lower detection limits while minimizing crosstalk. By partnering with Optical Filter Manufacturers and Optical Component and System Manufacturers, Cirtemo supports the development of unique applications that were previously unattainable with conventional optical products, all while maintaining a strong intellectual property position for its offerings.

Nirvana Sciences, Inc. is a company based in Research Triangle Park, North Carolina, that specializes in the development of synthetic bacteriochlorins and fluorescent dyes. Founded in 2011, the company focuses on creating new fluorescent dyes with ultra-narrow emissions, which are designed to enhance the efficiency of fluorescence-based medical diagnostics and imaging systems. These innovative dyes improve multiplexing capabilities, allowing researchers to gather more accurate data while simplifying detection processes. By commercializing advanced dye technologies, Nirvana Sciences aims to contribute significantly to the fields of medical diagnostics and imaging.

OBMedical Company is a medical device firm that specializes in the development, manufacturing, and sale of external maternal-fetal monitoring systems designed for laboring women. Founded in 2012 and based in Newberry, Florida, with an additional office in Norcross, Georgia, the company offers the LaborView sensor system, a wireless electrode-based monitoring solution that measures labor contractions and the heart rates of both mother and child. This innovative system enhances patient mobility during labor while ensuring accurate signal capture and digital signal processing, ultimately improving health and safety outcomes for mothers and infants. OBMedical's technology, which was developed in collaboration with the University of Florida and Convergent Engineering, was FDA cleared and became commercially available for hospital use in 2017. In late 2018, the company was acquired by Philips Healthcare, further extending the reach of its advanced maternal-fetal monitoring solutions.

Atlas Organics Inc. is a company that specializes in organics recycling services, focusing on the collection and recycling of food and yard waste. Founded in 2013 and headquartered in Spartanburg, South Carolina, the company operates in various regions, including San Antonio, Texas, and has established partnerships with municipalities to promote sustainability. Atlas Organics serves a diverse clientele, including businesses, schools, hospitals, and restaurants, by converting collected organic waste into high-quality compost products for agricultural, landscaping, and home gardening applications. The company aims to advance the "table to farm" movement, helping its customers achieve their sustainability goals while diverting compostable waste from landfills. Through its composting facilities, Atlas Organics contributes essential nutrients to soil health and supports the growth of beneficial microorganisms.

Physcient, Inc. is a medical device company based in Durham, North Carolina, established in 2007. The company specializes in the manufacturing of the Differential Dissector, a surgical instrument designed for blunt dissection. This device is utilized in a variety of surgical fields, including plastic surgery and open general surgical procedures such as thoracic, gastrointestinal, gynecological, urological, peripheral vascular, and orthopedic surgeries. Physcient focuses on developing modern technology for handheld surgical instruments that aim to facilitate faster patient recovery while maintaining existing surgical procedures. The founding team comprises three scientists and executives with extensive experience in innovating technologies for the life and health sciences.

Emergo Therapeutics, Inc. is a pharmaceutical company based in Durham, North Carolina, founded in 2016. The company specializes in developing therapeutic drugs aimed at improving immune system function and modulating inflammatory cytokines. Its primary focus is on creating treatment options for flu-like illnesses, specifically through the development of norketotifen for uncomplicated influenza. Emergo Therapeutics seeks to reduce the production of inflammatory cytokines released from mast cells, thereby enabling healthcare providers to manage symptoms and prevent adverse outcomes associated with various infectious diseases and related conditions.

CharlestonPharma, LLC, established in 2010 and headquartered in Charleston, South Carolina, specializes in developing therapeutic monoclonal antibodies targeting nucleolin, a protein overexpressed on cancer cells. The company holds worldwide licenses for producing these antibodies and using them to treat cancer patients, as well as for diagnostic applications involving nucleolin detection. Its focus is on demonstrating preclinical proof of concept for its anti-nucleolin antibodies, aiming to selectively kill cancer cells while minimizing toxicity to normal cells.

Brightfield Transportation Solutions, Inc. is a manufacturer and seller of electric vehicle charging stations, headquartered in Asheville, North Carolina. Established in 2005, the company focuses on developing solar-powered charging solutions for various markets, including electric utilities, workplaces, retail establishments, universities, and municipalities. Brightfield's offerings include DC fast chargers and Level 2 chargers, which have been installed through collaborations with notable organizations such as Nissan, BMW, EVgo, the U.S. Department of Energy, and the North Carolina Department of Commerce. The company is involved in the entire process of electric vehicle charging station deployment, encompassing planning, siting, installation, operation, and maintenance.

ThreatSwitch, Inc. is a software company based in Charlotte, North Carolina, that specializes in developing a business-to-business security compliance software platform. Founded in 2016, ThreatSwitch offers a SaaS solution tailored for organizations subject to stringent security regulations. The platform enables security professionals to efficiently manage various aspects of compliance programs, including personnel access, eligibility, investigations, and training progress. It facilitates self-reporting by employees and automates user activity tracking while allowing the creation of customized forms for data collection without compromising sensitive information. Additionally, the platform supports the management of visitor access requests, contributing to a streamlined security process. By leveraging ThreatSwitch's software, clients can achieve lower compliance costs, enhance employee engagement in security initiatives, and mitigate overall risk.

Seurat Technologies, Inc., incorporated in 2015 and headquartered in Mountain View, California, specializes in advanced 3D printing services aimed at revolutionizing industrial manufacturing. The company focuses on high-volume, decarbonized production of metal parts, utilizing its innovative Area Printing technology, which allows for the decoupling of resolution and speed. This scalable process positions Seurat to compete effectively with traditional manufacturing methods. The company's technology, originally developed at Lawrence Livermore National Laboratory, is supported by a robust portfolio of over 130 granted and pending patents. Seurat provides metal parts for original equipment manufacturers (OEMs) through long-term contracts, employing techniques such as direct metal writing and selective laser melting to ensure cost-effective production at scale.

OBMedical Company is a medical device firm that specializes in the development, manufacturing, and sale of external maternal-fetal monitoring systems designed for laboring women. Founded in 2012 and based in Newberry, Florida, with an additional office in Norcross, Georgia, the company offers the LaborView sensor system, a wireless electrode-based monitoring solution that measures labor contractions and the heart rates of both mother and child. This innovative system enhances patient mobility during labor while ensuring accurate signal capture and digital signal processing, ultimately improving health and safety outcomes for mothers and infants. OBMedical's technology, which was developed in collaboration with the University of Florida and Convergent Engineering, was FDA cleared and became commercially available for hospital use in 2017. In late 2018, the company was acquired by Philips Healthcare, further extending the reach of its advanced maternal-fetal monitoring solutions.

Kiyatec, LLC is a biotechnology company specializing in the development of advanced 3D cell-based assays aimed at enhancing preclinical drug discovery and clinical therapy applications. Founded in 2005 and based in Greenville, South Carolina, Kiyatec employs its proprietary 3DKUBE technology platform to create functional 3D models using patients' own living tumor cells. This innovative approach allows for the evaluation of various cancer therapies, providing insights into drug toxicity and efficacy before clinical trials. The company offers a range of services, including drug response profiling, predictions of patient responses to therapies, and cell-based assays for oncologists. Additionally, Kiyatec collaborates with biopharma clients on standard and custom assays and conducts research funded by the National Cancer Institute to develop 3D cell culture models for several types of cancer, such as breast cancer, glioblastoma, and lung cancer. By modeling complex human biology and simulating in vivo conditions, Kiyatec aims to improve treatment selection for cancer patients and support the development of medical devices and therapeutic drugs.

KWIPPED, Inc. is a B2B online equipment rental marketplace based in Wilmington, North Carolina, established in 2011. The company enables businesses to easily locate and rent specialized equipment from a global network of suppliers. KWIPPED's platform simplifies the sourcing process, reducing risk and ensuring quality while fostering trusted relationships between renters and suppliers. By offering a comprehensive selection of rental equipment, KWIPPED facilitates access for commercial applications, streamlining the equipment rental experience for its users.

Vendor Registry is a cloud-based platform designed to simplify the vendor registration process for local governments and institutions. By standardizing and centralizing traditionally paper-intensive workflows, the company aims to alleviate the burdens of repetitive paperwork that both vendors and government entities often face. This streamlined approach facilitates connections between vendors and governments, enhancing compliance and fostering competitive bidding. The platform is particularly beneficial for local small businesses, as it helps them generate new revenue opportunities while enabling governments to operate more efficiently with reduced costs. Ultimately, Vendor Registry seeks to create a mutually beneficial environment that supports both vendors and purchasing departments in managing taxpayer dollars more effectively.

Reveal Mobile, Inc. is a company that specializes in location-based marketing and analytics, catering to agencies, brands, media companies, and app publishers. Founded in 2004 and based in Raleigh, North Carolina, the company operates a platform that includes solutions such as VISIT Local, which offers foot traffic attribution and audience building, and VISIT Match, designed for instant audience scaling. Additionally, Reveal Mobile provides VISIT Data, a customizable location-data solution for enterprise applications. The platform facilitates the creation of targeted audience segments and enables clients to reach these audiences through various digital advertising channels, including social media. With a strong emphasis on privacy compliance, Reveal Mobile is a member of the Network Advertising Initiative and undergoes annual privacy certifications, ensuring that its services adhere to industry standards. The company's user-friendly interface simplifies audience analytics and post-campaign reporting, allowing clients to effectively measure the impact of their marketing efforts on foot traffic.

LUMINELLE is a company that specializes in developing advanced medical technology for uterine diagnostics and procedures. It has created the Luminelle DTx Hysteroscopy System, which facilitates office-based procedures, allowing physicians to accurately diagnose uterine disorders with minimal to no anesthesia. The system is designed to enhance the efficiency and cost-effectiveness of hysteroscopy and cystoscopy procedures, benefiting both medical practices and patients. By providing a convenient and reliable visual biopsy platform, LUMINELLE aims to optimize revenue for healthcare practices while improving patient care.

6AM City is a publishing company focused on enhancing audience participation and engagement within local communities. It operates a platform that aggregates, curates, and condenses essential local news, conversations, events, and trending topics, delivering this content through daily newsletters and social media channels. By producing brief and conversational newsletters that avoid political content, 6AM City aims to foster community involvement and dialogue. The company is dedicated to educating and activating its audience, ultimately creating a hub for local content that encourages sharing and participation, thus driving community connection and engagement.

ProAxion, Inc. is a Cary, North Carolina-based company that specializes in manufacturing cloud-connected sensors aimed at enhancing predictive maintenance for industrial machinery. Established in 2015, ProAxion develops a product called TACTIX, which enables remote monitoring of the health of rotating machines. Through the use of low-power sensors and advanced cloud computing technologies, the company provides solutions that improve equipment uptime and reliability while optimizing operational and maintenance costs. ProAxion's innovative approach contributes to the broader advancement of the Industrial Internet of Things, helping to prevent unexpected failures in mission-critical machines and ensuring the efficient operation of industrial facilities.

PharmRight Corporation, founded in 2013 and based in Charleston, South Carolina, specializes in the design and development of medical devices aimed at enhancing medication adherence at home. The company is known for its innovative product, Livi, an automated pill dispenser that aids users in managing their medication schedules independently. Livi is designed to support both patients and their caregivers by simplifying the process of managing multiple medications, thus providing essential assistance for effective treatment adherence. PharmRight's focus on improving medication management reflects its commitment to enhancing health outcomes through technology.

ProctorFree, Inc. is a provider of an automated online proctoring service aimed at enhancing academic integrity in online assessments. Founded in 2012 and based in Huntersville, North Carolina, the company offers a solution that employs facial recognition technology for student authentication and continuous identity verification throughout exams. This innovative approach eliminates the need for human proctors by utilizing standard computer equipment, including webcams and microphones, to monitor test-takers for any suspicious behavior indicative of cheating. After the exam, ProctorFree generates a TrustScore for faculty, detailing any anomalies observed during the testing session, along with a video recording for further review. By offering a cost-effective and efficient proctoring solution, ProctorFree seeks to transform online education, thereby increasing student enrollments and improving the overall perception of online learning.

Proterra Inc. is a manufacturer of zero-emission electric buses, primarily focused on providing sustainable transportation solutions for public and commercial transit. Founded in 2004 and headquartered in Burlingame, California, with additional offices in Greenville, South Carolina, and City of Industry, California, Proterra designs its products, including 35-foot and 40-foot electric buses, to meet the diverse needs of urban and regional transit routes. The company's Catalyst platform is noted for its modularity, allowing it to adapt to various operational demands while delivering high energy efficiency. Proterra also offers a broad range of services, including vehicle electrification solutions, fleet planning, charging infrastructure, and comprehensive vehicle maintenance programs. By facilitating the transition away from fossil fuels, Proterra aims to enhance environmental quality and reduce operational costs for fleet operators, contributing to significant reductions in greenhouse gas emissions.

Emrgy is a technology company established in 2014 that specializes in the design and deployment of modular, scalable hydroelectric solutions. The company focuses on providing innovative hydroelectric turbines that generate electricity from slow or shallow water flows. Emrgy’s products incorporate advanced technologies, including turbines, magnetic gearboxes, and compact hydroelectric power generators, which significantly lower energy costs. These solutions enable power generation companies to effectively harness electricity from slow-moving rivers and streams, positioning Emrgy as a key player in the renewable energy sector as the industry shifts toward distributed energy sources.

Get Spiffy, Inc. is a mobile service company based in Durham, North Carolina, that specializes in on-demand car washing, detailing, nano-ceramic coating, and oil change services. Founded in 2014, the company utilizes a smartphone application that facilitates both communication and payment for its services. Get Spiffy emphasizes environmental responsibility, ensuring that all car washes are eco-friendly. Through its innovative approach, the company aims to provide convenient and efficient automotive care to customers in the Triangle area and beyond.

TiO is a developer of customizable smart home solutions, primarily aimed at builders. The company specializes in home automation and control systems that enhance comfort and convenience in residential spaces. TiO's offerings include lighting control and wireless audio systems that seamlessly integrate with a variety of smart home devices and well-known household brands. This enables users to manage their home environment easily through simple hardware and software products. TiO focuses on providing a user-friendly experience that fosters both enjoyment and peace of mind within the home.

LUMINELLE is a company that specializes in developing advanced medical technology for uterine diagnostics and procedures. It has created the Luminelle DTx Hysteroscopy System, which facilitates office-based procedures, allowing physicians to accurately diagnose uterine disorders with minimal to no anesthesia. The system is designed to enhance the efficiency and cost-effectiveness of hysteroscopy and cystoscopy procedures, benefiting both medical practices and patients. By providing a convenient and reliable visual biopsy platform, LUMINELLE aims to optimize revenue for healthcare practices while improving patient care.

CharlestonPharma, LLC, established in 2010 and headquartered in Charleston, South Carolina, specializes in developing therapeutic monoclonal antibodies targeting nucleolin, a protein overexpressed on cancer cells. The company holds worldwide licenses for producing these antibodies and using them to treat cancer patients, as well as for diagnostic applications involving nucleolin detection. Its focus is on demonstrating preclinical proof of concept for its anti-nucleolin antibodies, aiming to selectively kill cancer cells while minimizing toxicity to normal cells.

Vendor Registry is a cloud-based platform designed to simplify the vendor registration process for local governments and institutions. By standardizing and centralizing traditionally paper-intensive workflows, the company aims to alleviate the burdens of repetitive paperwork that both vendors and government entities often face. This streamlined approach facilitates connections between vendors and governments, enhancing compliance and fostering competitive bidding. The platform is particularly beneficial for local small businesses, as it helps them generate new revenue opportunities while enabling governments to operate more efficiently with reduced costs. Ultimately, Vendor Registry seeks to create a mutually beneficial environment that supports both vendors and purchasing departments in managing taxpayer dollars more effectively.

KWIPPED, Inc. is a B2B online equipment rental marketplace based in Wilmington, North Carolina, established in 2011. The company enables businesses to easily locate and rent specialized equipment from a global network of suppliers. KWIPPED's platform simplifies the sourcing process, reducing risk and ensuring quality while fostering trusted relationships between renters and suppliers. By offering a comprehensive selection of rental equipment, KWIPPED facilitates access for commercial applications, streamlining the equipment rental experience for its users.

Proterra Inc. is a manufacturer of zero-emission electric buses, primarily focused on providing sustainable transportation solutions for public and commercial transit. Founded in 2004 and headquartered in Burlingame, California, with additional offices in Greenville, South Carolina, and City of Industry, California, Proterra designs its products, including 35-foot and 40-foot electric buses, to meet the diverse needs of urban and regional transit routes. The company's Catalyst platform is noted for its modularity, allowing it to adapt to various operational demands while delivering high energy efficiency. Proterra also offers a broad range of services, including vehicle electrification solutions, fleet planning, charging infrastructure, and comprehensive vehicle maintenance programs. By facilitating the transition away from fossil fuels, Proterra aims to enhance environmental quality and reduce operational costs for fleet operators, contributing to significant reductions in greenhouse gas emissions.

Atlas Organics Inc. is a company that specializes in organics recycling services, focusing on the collection and recycling of food and yard waste. Founded in 2013 and headquartered in Spartanburg, South Carolina, the company operates in various regions, including San Antonio, Texas, and has established partnerships with municipalities to promote sustainability. Atlas Organics serves a diverse clientele, including businesses, schools, hospitals, and restaurants, by converting collected organic waste into high-quality compost products for agricultural, landscaping, and home gardening applications. The company aims to advance the "table to farm" movement, helping its customers achieve their sustainability goals while diverting compostable waste from landfills. Through its composting facilities, Atlas Organics contributes essential nutrients to soil health and supports the growth of beneficial microorganisms.

PharmRight Corporation, founded in 2013 and based in Charleston, South Carolina, specializes in the design and development of medical devices aimed at enhancing medication adherence at home. The company is known for its innovative product, Livi, an automated pill dispenser that aids users in managing their medication schedules independently. Livi is designed to support both patients and their caregivers by simplifying the process of managing multiple medications, thus providing essential assistance for effective treatment adherence. PharmRight's focus on improving medication management reflects its commitment to enhancing health outcomes through technology.

TARGET PharmaSolutions, Inc. specializes in providing real-world data solutions tailored for drug development and commercialization. Founded in 2015 and headquartered in Durham, North Carolina, the company focuses on creating custom datasets and analyses to tackle complex healthcare evidence questions and quality initiatives. It offers a comprehensive health evidence solution that aggregates real-world data from a network of participating sites, in addition to providing bio specimen samples and consulting services. The company's foundation was inspired by the success of HCV-TARGET, a model established in 2011 that demonstrated the efficacy of real-world data in clinical research and regulatory processes. Through its innovative approaches, TARGET PharmaSolutions aims to enhance the drug development process and support evidence-based decision-making in healthcare.

Baebies, Inc., founded in 2014 by Richard West and Vamsee Pamula, specializes in manufacturing screening and pediatric testing equipment for newborn babies. Based in Durham, North Carolina, the company produces SEEKER, a laboratory solution that performs multiple assays simultaneously to measure lysosomal enzyme activity from a single dried blood spot specimen. Additionally, Baebies manufactures FINDER, a near-patient testing device designed for pediatric diagnostics. The company's technology leverages digital microfluidics to maximize diagnostic yield from small sample volumes. SEEKER is FDA authorized and CE marked, while the FINDER platforms are also CE marked, with the FINDER 1.5 SARS-CoV-2 test receiving emergency use authorization from the FDA. Baebies serves hospitals and public health labs, aiming to enhance early disease detection and improve diagnostic capabilities for newborns and patients worldwide.

OBMedical Company is a medical device firm that specializes in the development, manufacturing, and sale of external maternal-fetal monitoring systems designed for laboring women. Founded in 2012 and based in Newberry, Florida, with an additional office in Norcross, Georgia, the company offers the LaborView sensor system, a wireless electrode-based monitoring solution that measures labor contractions and the heart rates of both mother and child. This innovative system enhances patient mobility during labor while ensuring accurate signal capture and digital signal processing, ultimately improving health and safety outcomes for mothers and infants. OBMedical's technology, which was developed in collaboration with the University of Florida and Convergent Engineering, was FDA cleared and became commercially available for hospital use in 2017. In late 2018, the company was acquired by Philips Healthcare, further extending the reach of its advanced maternal-fetal monitoring solutions.