Venrock

Astronomer is a data engineering software company that builds a managed Apache Airflow platform. Founded in 2014 and based in Cincinnati, Astronomer offers Astro, a data orchestration platform powered by Apache Airflow that enables data teams to build, run, and observe data pipelines-as-code. The platform is designed to deploy, manage, and scale distributed Airflow workflows with features such as isolated resource allocation and controlled user access, supporting data engineers, data scientists, and data analysts in delivering trusted analytics. Astronomer's solutions help organizations increase data availability and visibility by making pipelines observable and governance-friendly across environments.

Suki develops AI-driven voice solutions for healthcare providers. Its primary product, Suki Assistant, uses artificial intelligence and natural language processing to create detailed clinical notes during or after consultations, enabling physicians to complete administrative tasks more efficiently.

Element Biosciences develops innovative genetic analysis tools for research and diagnostic markets. Founded in 2017, the company specializes in a disruptive DNA sequencing technology that offers high-quality data, workflow flexibility, and affordable access to next-generation sequencing.

RefleXion Medical Inc. is a medical equipment company based in Hayward, California, focused on revolutionizing cancer treatment through its biologically-guided radiotherapy system (BgRT). This innovative technology allows tumors to continuously signal their location during treatment, enabling the simultaneous targeting of multiple tumors, even in cases of metastasized cancer. The RefleXion X1 machine is cleared for various forms of radiotherapy, including stereotactic body radiotherapy, stereotactic radiosurgery, and intensity-modulated radiotherapy. The BgRT system utilizes positron-emission tomography (PET) imaging data to synchronize tumor location information with the linear accelerator, allowing for real-time adjustments in treatment delivery with subsecond latency. RefleXion Medical has established strategic collaborations with Telix Pharmaceuticals Limited and HealthMyne Inc. since its incorporation in 2009.

Kyruus, Inc. is a Boston-based company that develops web-based software solutions aimed at optimizing physician networks for hospitals, health systems, and life science companies. Founded in 2010, Kyruus offers a suite of analytically driven products designed to enhance provider search and scheduling, ensuring that patients are matched with the most suitable healthcare providers. Key offerings include Kyruus Passport, which allows physicians to track their activity and productivity, and Kyruus Profiles, which enables administrators to analyze physician performance metrics. Additionally, the company provides Kyruus MDSeekyr, a platform for identifying high-value providers, and Kyruus Insight Reports, which help executives evaluate network activity and performance trends. By leveraging a proprietary provider data management platform, Kyruus enhances patient engagement and aligns provider supply with patient demand, ultimately improving the overall healthcare experience. Kyruus also maintains offices in San Francisco and New York.

Inscripta is a gene editing technology company developing scalable digital genome engineering based on CRISPR approaches. It offers MADzymes enzymes for precision editing and is building a benchtop platform comprising an instrument, consumables, software, and assays that enables automated, massively parallel, trackable editing of single cells. The platform aims to lower technical and licensing barriers, delivering push-button workflows and low-cost libraries of thousands of designer proteins, pathways, or genome variants, each with defined and trackable mutations. The company also pursues collaboration by making its MAD7 nuclease available free for research and development to broaden access and accelerate biological discovery.

Dstillery is a digital advertising technology company that develops a digital intelligence platform for brands and media partners. The platform enables brand-specific and cross-channel marketing across mobile, desktop, and video by integrating mobile location insights with desktop behaviors to optimize campaigns. It includes Dscover Maps, a geospatial insights tool that analyzes market composition by geography or location, and uses artificial intelligence to derive customer insights for audience targeting. The company emphasizes privacy-friendly options such as ID-free behavioral targeting and offers Custom AI Audiences for brand-specific targeting, supporting programmatic advertising for brands and agencies in the United States.

ShockWave Medical is a medical device company focused on developing and commercializing intravascular lithotripsy technology to treat calcified plaque in peripheral vascular, coronary vascular, and valvular diseases. The company markets lithoplasty catheters, including M5 for above-the-knee peripheral artery disease, C2 for coronary artery disease, and S4 for below-the-knee lesions, designed to modify calcium and improve vessel compliance before angioplasty or stent delivery. Its sonic pressure wave technology aims to limit injury to healthy tissue and facilitate procedures such as transcatheter coronary interventions and valve therapies. The business serves interventional cardiologists, vascular surgeons, and interventional radiologists through a direct sales force and distributors. It operates in the United States, Germany, the rest of Europe, and other international markets. Founded in 2009, ShockWave Medical is headquartered in Santa Clara, California.

Milestone Pharmaceuticals is a biopharmaceutical company focused on developing and commercializing etripamil, a rapid-onset calcium channel blocker for cardiovascular conditions. The lead product is etripamil, administered as a nasal spray for self-treatment of episodes of paroxysmal supraventricular tachycardia, with ongoing Phase III studies in the United States and Canada. The company is also advancing development for other cardiovascular indications, including atrial fibrillation and angina, with a Phase II program for atrial fibrillation with rapid ventricular response. Founded in 2003, Milestone is headquartered in Montreal.

CTERA Networks Ltd., established in 2008, specializes in providing a private cloud storage service platform that centrally manages security and governance for organizations. Its core product, the CTERA Enterprise File Services Platform, enables IT departments to deliver secure file services from any cloud, serving diverse industries such as financial services, healthcare, and government. The platform modernizes storage, backup, and file collaboration across dispersed enterprises, ensuring data protection, GDPR compliance, and swift ransomware recovery. CTERA partners with tech giants like IBM, AWS, and Cisco, and has a global presence with offices in multiple countries.

Salsify is an e-commerce software startup based in Boston, Massachusetts, founded in 2012 by Jason Purcell, Jeremy Redburn, and Rob Gonzalez. The company provides a comprehensive platform known as Commerce Experience Management (CommerceXM), which integrates Product Experience Management tools—including Product Information Management (PIM), Digital Asset Management (DAM), and an Experience Builder—with essential commerce functionalities. This platform is designed to facilitate sales across various channels, including retailers, distributors, marketplaces, social commerce, and direct-to-consumer (D2C) sites. By offering these tools, Salsify aims to enhance brand visibility and performance on digital shelves, helping businesses optimize their product presentation and inventory management to drive online sales effectively.

Hua Medicine is a clinical-stage drug development company in China focused on therapies for diabetes and CNS disorders. It develops Dorzagliatin (also known as HMS5552), an oral, first-in-class glucokinase activator for type 2 diabetes, and has advanced Dorzagliatin into NDA-enabling work and Phase III trials in China, including studies in drug-naive and metformin-treated patients. The company is pursuing Dorzagliatin in combination with metformin and in combination with DPP-4 inhibitors, SGLT-2 inhibitors, and insulin in various development stages. In addition, Hua Medicine is developing mGluR5 candidates for Parkinson's disease and related levodopa-induced dyskinesia. The company was founded in 2011 and is headquartered in Shanghai, China.

Tricida, Inc. is a late-stage pharmaceutical company based in South San Francisco, California, established in 2013. The company specializes in the development and commercialization of TRC101, a non-absorbed, orally-administered polymer designed to treat metabolic acidosis in patients with chronic kidney disease (CKD). Metabolic acidosis, a common complication of CKD, can accelerate kidney deterioration and is associated with serious health risks, including muscle wasting and loss of bone density. Tricida has successfully completed a Phase 3, double-blind, placebo-controlled trial of TRC101, positioning the company to address a significant unmet medical need in CKD management through the innovative approach of binding and removing acid from the gastrointestinal tract.

VeloCloud Networks is a cloud-delivered software-defined wide-area networking provider that simplifies branch WAN networking by automating deployment and improving performance across private, broadband Internet, and LTE links for distributed enterprises. Its SD-WAN solution combines a cloud-based control plane with enterprise-grade branch and data center appliances and software-defined automation to enable centralized configuration and real-time monitoring. The platform delivers secure, optimized paths to cloud services, private data centers, and enterprise applications, enabling policy-based access for multiple locations. By routing traffic through the cloud network and supporting orchestration of data flows, VeloCloud aims to deliver scalable, flexible connectivity that supports application growth and simplifies branch and end-point implementations.

Dynamic Signal, established in 2010 and headquartered in San Bruno, California, specializes in employee communication and engagement. Its platform connects companies with their employees, facilitating the dissemination of timely, relevant content across various channels and devices. This enhances productivity, fosters employee engagement, and amplifies corporate messaging. Dynamic Signal serves hundreds of global enterprises, including 85 Fortune 500 companies, such as IBM, Salesforce, and Edelman.

Shape Security, Inc. is a cybersecurity company specializing in protecting web and mobile applications from automated cyber-attacks. Founded in 2011 and headquartered in Santa Clara, California, with additional offices in Sydney and London, the company utilizes AI-powered defenses to mitigate fraud, abuse, and attacks on applications and APIs. Its key products include ShapeShifter Elements, which enforces real-time security measures, and Shape Protection Manager, a cloud-based management tool for its services. Shape Security has successfully deflected over $1 billion in fraud losses across various sectors, including retail, finance, travel, healthcare, and government, safeguarding organizations from reputational damage and financial losses.

PowerVision, Inc. is a medical device company based in Belmont, California, focused on developing advanced intraocular lenses (IOLs) designed to restore vision for individuals affected by presbyopia and cataracts. Established in 2002, the company has created the FluidVision accommodating intraocular lens technology, which simulates the natural function of a healthy eye. This innovative lens utilizes a small amount of fluid to adjust its shape dynamically, allowing for clear vision at various distances. PowerVision aims to address the vision challenges faced by millions, particularly the over 20 million individuals in the U.S. with cataracts and the more than 90 million affected by presbyopia. The FluidVision lens represents a significant advancement in vision correction, potentially freeing patients from the need for glasses or other vision correction methods. In 2019, PowerVision was acquired by Alcon Laboratories, Inc.

Dollar Shave Club is a lifestyle brand and e-commerce company that develops and sells grooming products for men. It uses an exclusive R&D process that includes botanicals and chemists to create its own products at affordable prices. Founded in 2012 and based in Santa Monica, California, the company offers razors, blades, shave butter, aftershave liquids, face washes, wipes, and gift cards, primarily through a subscription model that provides convenient access to products at reasonable prices.

Cloudflare, Inc. is a San Francisco-based software company that specializes in web performance and security services for businesses globally. It operates a cloud platform that integrates various network services, including security solutions such as Cloud Firewall, Bot Management, and Distributed Denial of Service protection. The company enhances website performance through its Content Delivery Network (CDN) and intelligent routing, while also providing optimization tools for content and images. Furthermore, Cloudflare offers reliability solutions like Load Balancing and DNS services, alongside security features aimed at protecting internal resources through Zero Trust Security and Secure Web Gateway. Its consumer offerings include a DNS resolver and a virtual private network (VPN) designed to secure mobile traffic. Cloudflare serves diverse industries, including technology, healthcare, financial services, and government, and was founded in 2009.

AveXis, operating as Novartis Gene Therapies, Inc., is a biotechnology company focused on developing and commercializing gene therapies for rare and life-threatening neurological genetic diseases. Acquired by Novartis in 2018, the company specializes in innovative treatments such as motor neuron cell-targeted gene replacement therapy aimed at conditions like spinal muscular atrophy, Rett syndrome, and amyotrophic lateral sclerosis. These therapies are designed to assist healthcare institutions in addressing diseases that cause progressive muscle weakness, paralysis, and ultimately, death. Through its advancements in gene therapy, AveXis is dedicated to improving the lives of patients and families impacted by these severe genetic disorders.

CytomX Therapeutics is a clinical-stage oncology-focused biopharmaceutical company that develops proteolytically-activated antibodies based on its Probody technology platform. Probody therapeutics are designed to be activated by the tumor microenvironment, enabling targeted cancer immunotherapies with reduced activity in healthy tissues. The company advances antibody and antibody-drug conjugate programs such as CX-072 (PD-L1), CX-2009 (CD166-targeted PDC), BMS-986249 (CTLA-4 Probody), CX-2029 (CD71-targeted PDC), and BMS-986288 (CTLA-4 Probody) in clinical research, and maintains collaborations with AbbVie, Amgen, Bristol-Myers Squibb, ImmunoGen, Pfizer, and Astellas to develop Probody therapeutics. Founded in 2008 and headquartered in South San Francisco, the company aims to improve the precision and safety of antibody-based therapies for cancer and inflammatory diseases.

REGENXBIO is a clinical-stage biotechnology company developing gene therapy product candidates using its proprietary NAV Technology Platform. This platform delivers genes to cells to address genetic defects or produce therapeutic proteins. REGENXBIO's pipeline includes RGX-314 for wet age-related macular degeneration, RGX-121 and RGX-111 for mucopolysaccharidoses, RGX-181 for late infantile neuronal ceroid lipofuscinosis type II disease, and RGX-501 for homozygous familial hypercholesterolemia. The company also licenses its platform to other biopharmaceutical companies.

Dataminr is a technology company that leverages artificial intelligence to monitor public information sources. It specializes in detecting and alerting clients to high-impact events and emerging risks in real-time, enabling them to make informed decisions across various sectors including finance, security, crisis management, and news.

Ascendis Pharma is a biopharmaceutical company that uses its TransCon prodrug technology platform to create long-acting therapies across endocrinology and oncology. The company's TransCon growth hormone targets growth hormone deficiency in children and has completed Phase III development; TransCon PTH is in Phase II for hypoparathyroidism, and TransCon CNP is in Phase II for achondroplasia; it is pursuing preclinical oncology programs and evaluating systemic and localized delivery; the platform enables control of exposure via TransCon carrier and linker to determine dosing frequency, with prodrugs releasing the active drug in its native form. Ascendis collaborates with Sanofi to co-develop TransCon technologies for diabetes. The company was founded in 2006 and is headquartered in Hellerup, Denmark.

Personal Capital Corporation is a digital wealth management company that offers financial advisory services and innovative software solutions to help individuals manage their finances effectively. Founded in 2009 and headquartered in Redwood Shores, California, the company provides tools that allow users to monitor income, spending, and investment performance in one place. Its services include wealth management, personalized financial planning, risk assessments, and investment checkup tools. With a user base exceeding 2.5 million customers, Personal Capital combines advanced technology with expert guidance from registered investment advisors to deliver customized financial strategies aligned with clients' goals. Originally known as SafeCorp Financial Corp., the company rebranded to Personal Capital in June 2010, reflecting its commitment to enhancing personal financial management through technology.

PowerVision, Inc. is a medical device company based in Belmont, California, focused on developing advanced intraocular lenses (IOLs) designed to restore vision for individuals affected by presbyopia and cataracts. Established in 2002, the company has created the FluidVision accommodating intraocular lens technology, which simulates the natural function of a healthy eye. This innovative lens utilizes a small amount of fluid to adjust its shape dynamically, allowing for clear vision at various distances. PowerVision aims to address the vision challenges faced by millions, particularly the over 20 million individuals in the U.S. with cataracts and the more than 90 million affected by presbyopia. The FluidVision lens represents a significant advancement in vision correction, potentially freeing patients from the need for glasses or other vision correction methods. In 2019, PowerVision was acquired by Alcon Laboratories, Inc.

Smartling is a language service and technology provider that specializes in content localization across various devices and platforms. Established in 2009 by Jack Welde and Andrey Akselrod, the company is headquartered in New York, New York. Smartling offers a Translation Management Platform that empowers brands to expand into new markets and enhance customer engagement. Its cloud-based enterprise translation software facilitates the translation and deployment of multilingual websites, mobile applications, and business documents, enabling organizations to create native experiences for their audiences. Notable clients include British Airways, Uber, and Spotify, which utilize Smartling's solutions to strengthen their global presence and improve their international operations.

Phononic designs and manufactures solid-state cooling and heating solutions. Its products include thermoelectric devices and heat pumps used in electronics cooling, refrigeration, and climate control applications. Founded in 2008, the company is headquartered in Durham, North Carolina.

PowerVision, Inc. is a medical device company based in Belmont, California, focused on developing advanced intraocular lenses (IOLs) designed to restore vision for individuals affected by presbyopia and cataracts. Established in 2002, the company has created the FluidVision accommodating intraocular lens technology, which simulates the natural function of a healthy eye. This innovative lens utilizes a small amount of fluid to adjust its shape dynamically, allowing for clear vision at various distances. PowerVision aims to address the vision challenges faced by millions, particularly the over 20 million individuals in the U.S. with cataracts and the more than 90 million affected by presbyopia. The FluidVision lens represents a significant advancement in vision correction, potentially freeing patients from the need for glasses or other vision correction methods. In 2019, PowerVision was acquired by Alcon Laboratories, Inc.

Aria Systems provides a cloud-based platform for managing recurring revenues. It offers Aria, an enterprise-grade solution for subscription-based billing, serving clients across hi-tech, media, telecom, and finance industries worldwide.

Martini Media Network, Inc. is a digital media and content platform based in San Francisco, California, specializing in engaging affluent audiences. Founded in 2007, the company offers tailored solutions for brands to deliver media campaigns that integrate content, videos, and social functionality across niche sites. Martini Media focuses on invitation-only platforms centered around business and lifestyle categories, enabling effective engagement with influential consumers. By leveraging insights into online behaviors and interests of the affluent market, the company partners with clients and agencies to craft customized advertising, publishing, and storytelling programs that align with specific marketing objectives. As of June 2015, Martini Media operates as a subsidiary of Evolve Media, LLC.

Atrenta is a provider of innovative solutions for the semiconductor and consumer electronics industries, specializing in design efficiency through its SpyGlass Predictive Analysis software platform. This platform offers early design insights into the performance, power, and area requirements of complex system on chips (SoCs), which are essential for modern consumer electronics. By enabling design engineers to identify structural, coding, and consistency issues in register transfer language (RTL), Atrenta's technology allows for enhanced testability during RTL creation. The company's patented solutions are utilized by over two hundred companies and thousands of design engineers globally, helping to mitigate risks and reduce costs before the deployment of traditional electronic design automation (EDA) tools. SpyGlass serves as an interactive guidance system, optimizing the implementation process for complex SoCs and ensuring greater efficiency and confidence in design outcomes.

Achaogen, Inc. is a biopharmaceutical company based in South San Francisco, California, that specializes in the development and commercialization of antibacterial agents targeting multi-drug resistant (MDR) gram-negative infections. The company's primary focus is on plazomicin, which is intended for treating serious bacterial infections caused by MDR enterobacteriaceae, including carbapenem-resistant strains. Additionally, Achaogen is developing C-Scape, an orally-administered combination of clavulanate and ceftibuten aimed at addressing serious infections linked to expanded spectrum beta-lactamases producing enterobacteriaceae. Achaogen has established collaborations with various organizations, including Thermo Fisher Scientific and Ionis Pharmaceuticals, to support its drug development efforts. The company was incorporated in 2002, but faced financial difficulties, leading to a Chapter 11 bankruptcy filing in 2019, which culminated in a liquidation plan approved in 2020. All of Achaogen's revenue has been derived from government contracts for research and development within the United States.

AppNexus is a cloud-based advertising technology platform that enables and optimizes programmatic online advertising for buyers and sellers of digital inventory. The platform supports real-time bidding, trading desks, and marketplaces to maximize yield and campaign performance, and provides a digital delivery system and the AppNexus Publisher Suite for ad serving, planning, forecasting, diverse marketplace sales, and direct campaign management. It also offers PriceCheck, a header bidding solution for banner, video, and interstitial units, and AppNexus Apps, an application platform for third-party vendors to develop features for clients and reach new audiences.

Transonic Combustion, founded in 2006 and headquartered in Camarillo, California, specializes in advanced fuel injection systems designed to enhance the efficiency of modern automotive engines. The company's TSCi™ fuel delivery technology is tailored for global automotive manufacturers, aiming to improve fuel efficiency and performance in various engine platforms. Transonic Combustion is backed by notable venture capital firms, including Venrock, Khosla Ventures, Rustic Canyon, and Saints Capital, indicating strong investor confidence in its innovative approach to fuel technology.

Castlight Health is dedicated to simplifying the healthcare experience and promoting healthier, more productive lives. Its health navigation platform integrates with various health vendors, benefits resources, and plan designs, creating a comprehensive application that addresses diverse health needs. By tailoring guidance to individual profiles, Castlight assists users, whether they are healthy, managing chronic conditions, or seeking medical care, in accessing optimal resources. The company aims to help organizations manage rising healthcare costs and enhance the value of their benefits investments. Since its inception, Castlight has introduced innovative solutions such as data-driven price transparency tools and a consumer-friendly wellbeing platform. Currently, it serves millions of users and partners with numerous large employers, positioning itself as a key player in the healthcare sector. Castlight is headquartered in San Francisco.

Cerulean Pharma Inc. is a privately-held biopharmaceutical company specializing in the development of innovative nanotechnology-based therapeutics, primarily targeting oncology, cardiovascular, autoimmune, and inflammatory diseases. The company focuses on creating nanoparticle-drug conjugates that aim to selectively target tumors, minimize toxicity, and facilitate drug combinations. Among its notable products is Ovaprene, a contraceptive designed to offer multiple weeks of protection without hormones, addressing needs in fertility and vaginal health. Cerulean Pharma boasts a distinguished management team and advisory board, comprising experts with extensive experience in product development and scientific advancements from leading organizations and institutions, including GlaxoSmithKline, Merck, and Harvard Medical School.

Intuity Medical, Inc. is a medical technology company specializing in blood glucose monitoring systems for diabetes management. Founded in 2002 and headquartered in Fremont, California, the company is known for its innovative POGO Automatic Blood Glucose Monitoring System. This system is the first FDA-cleared automatic, one-step blood glucose meter that integrates lancing, blood collection, and analysis into a single cartridge capable of performing ten tests. Intuity Medical aims to provide a convenient and discreet solution for patients who require regular blood glucose testing, enhancing their ability to manage their diabetes effectively. The company was previously known as Rosedale Medical, Inc. until it rebranded in June 2007.

Gazelle is an e-commerce platform focused on the buying and selling of used electronic devices, including smartphones, tablets, laptops, and desktops. Founded in 2006 and headquartered in Boston, Massachusetts, with operations in Louisville, Kentucky, the company offers consumers an easy way to acquire cost-effective electronic gadgets. Gazelle pays cash for pre-owned devices, which it inspects and certifies before reselling them to customers. This process not only provides a convenient option for consumers looking to stay connected but also promotes the recycling of electronic gadgets, contributing to sustainability in the technology sector.

Nanosys, Inc. is a company that specializes in the development and manufacturing of quantum dot technology aimed at enhancing high-definition viewing experiences across various display applications. Founded in 2001 and headquartered in Milpitas, California, Nanosys produces Quantum Dot Concentrate materials and Quantum Dot Enhancement films that improve the performance of a wide range of consumer electronics, including televisions, tablets, and smartphones. The company's quantum dots are nanoscale semiconductors that enable displays to achieve greater brightness and a wider color gamut, resulting in more lifelike images. This technology is compatible with various display types, including LED-LCDs, OLEDs, and micro-LEDs. Nanosys has seen significant adoption of its technology, with over 20 million devices shipped in numerous products, thus contributing to advancements in the display industry.

Zeltiq Aesthetics, Inc. is a medical technology company founded in 2005 and headquartered in Pleasanton, California. It specializes in the development and commercialization of non-invasive products aimed at the selective reduction of fat. The company's flagship product, the CoolSculpting system, employs a patented method known as Cryolipolysis, which utilizes precisely controlled cooling to target and eliminate stubborn fat cells without damaging surrounding tissue. This FDA-cleared device is designed for various applications in dermatologic treatments and is marketed primarily to dermatologists, plastic surgeons, and aesthetic specialists across North America, the Asia-Pacific, Europe, and Latin America. Zeltiq Aesthetics was formerly known as Juniper Medical, Inc. and rebranded in July 2007. As of 2017, it operates as a subsidiary of Allergan plc.

Quantenna Communications, Inc. specializes in the design, development, and marketing of advanced high-speed wireless communication solutions that facilitate wireless local area networking. Founded in 2006 and headquartered in San Jose, California, the company offers a diverse portfolio of products, including radio frequency and digital baseband chips that adhere to various IEEE Wi-Fi standards, such as 802.11n, 802.11ac, and draft Wi-Fi 6. Quantenna's offerings also include Qdock, a software framework that integrates third-party applications with its Wi-Fi solutions. The company's products cater to a wide range of applications, including home networking devices, retail, outdoor, small and medium businesses, enterprise, industrial, and consumer electronics. Quantenna sells its Wi-Fi solutions directly to original equipment manufacturers, original design manufacturers, and third-party distributors, with a significant portion of its revenue generated from the Asia-Pacific region. As of 2019, Quantenna operates as a subsidiary of ON Semiconductor Corporation.

Intuity Medical, Inc. is a medical technology company specializing in blood glucose monitoring systems for diabetes management. Founded in 2002 and headquartered in Fremont, California, the company is known for its innovative POGO Automatic Blood Glucose Monitoring System. This system is the first FDA-cleared automatic, one-step blood glucose meter that integrates lancing, blood collection, and analysis into a single cartridge capable of performing ten tests. Intuity Medical aims to provide a convenient and discreet solution for patients who require regular blood glucose testing, enhancing their ability to manage their diabetes effectively. The company was previously known as Rosedale Medical, Inc. until it rebranded in June 2007.

Boston Power is a developer of advanced lithium-ion battery technology, focusing on enhancing the quality and safety of energy storage solutions. The company has created the Sonata technology platform, which offers batteries that charge more quickly, have extended lifespans, and provide superior performance compared to existing options in the market. This innovative technology is designed for various applications, including consumer electronic devices such as laptops, PDAs, and mobile phones, as well as electric vehicles and utility energy storage systems. By delivering unmatched capabilities, Boston Power aims to meet the growing demands for efficient and reliable portable power sources.

Awarepoint Corporation is a provider of cloud-based real-time locating systems (RTLS) that enhance operational efficiency across various industries, with a strong focus on healthcare. Established in 2002 and headquartered in San Diego, California, the company offers a suite of solutions that includes analytical tools for transforming location data into actionable insights, as well as managed services encompassing analysis, configuration, installation, validation, and training. Awarepoint's RTLS solutions are particularly valuable in acute care hospitals, addressing challenges related to asset management, compliance, and patient throughput. The company also offers a Temperature Monitoring System designed to help medical facilities comply with guidelines for vaccine storage. Awarepoint's integrated platform allows healthcare organizations to optimize workflows and communication, improve staff efficiency, and enhance patient satisfaction, ultimately leading to better clinical and financial outcomes.

Kineto Wireless is a privately held company that specializes in assisting mobile operators with the transition to IP-based services. The company's solutions are designed to help operators compete against over-the-top (OTT) service providers by enhancing their voice and messaging services using Rich Communications Suite (RCS) technology through its Smart Comms application. Additionally, Kineto offers Smart Wi-Fi, which converts existing Wi-Fi access points into virtual femtocells on the mobile operator’s network. This allows smartphone users to receive various mobile services over Wi-Fi, including voice, short messaging services, data, instant messaging services and web-based services. The company's notable customers and partners include major telecommunications companies such as Orange, Rogers Wireless, T-Mobile USA, Huawei, Samsung Group, and ZTE.

DATAllegro provides integrated data warehousing services.

Genband is a global provider of high-performance IP gateways and session border controllers, which are integral components in fixed and mobile networks worldwide. The company's products facilitate secure communication by evolving and enhancing networks' capabilities.

Imperva, Inc. is a cybersecurity company based in Redwood Shores, California, that specializes in protecting critical business data and applications across cloud and on-premises environments. Founded in 2002, Imperva develops a range of security solutions, including its SecureSphere product line, which offers database, file, and web application security. The company’s services also include Incapsula, which provides cloud-based website security and distributed denial of service protection, as well as ThreatRadar for crowdsourced security intelligence. Additionally, CounterBreach safeguards enterprise data against loss from compromised users, and Imperva Camouflage Data Masking allows for the secure use of sensitive information in development and testing. Imperva serves various sectors, including finance, healthcare, retail, and telecommunications, through a network of distributors and resellers, while also offering ongoing support and professional services.

Teranetics is a prominent mixed-signal integrated circuit (IC) company specializing in the development of silicon products tailored for advanced communication applications. The company boasts a core development team with a proven history of successful product innovations in both advanced communication systems and silicon technology. Teranetics is supported by a consortium of venture investors who possess extensive experience and achievements in the semiconductor and communication sectors.

Digit Wireless, operates as a user interface innovation company. It offers Fastap keypad technology solutions that enable to discover, access, and use messaging, mobile data, and voice services. The company licenses its technology to mobile manufacturers and operators. Digit Wireless, Inc. was founded in 2000 and is headquartered in Burlington, Massachusetts with additional offices in Beijing, Shanghai, Hong Kong, London, and Seoul.

Vitae Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company headquartered in Fort Washington, Pennsylvania, that specializes in discovering and developing novel small molecule drugs aimed at addressing significant unmet medical needs. Founded in 2001, Vitae's product pipeline includes VTP-43742, currently in Phase I clinical trials for autoimmune disorders such as psoriasis and multiple sclerosis, and VTP-38543, which is in Phase IIa trials for atopic dermatitis. The company is also advancing VTP-34072 in Phase II trials for type 2 diabetes and VTP-38443 for acute coronary syndrome, as well as BI 1147560 for Alzheimer's disease. Vitae Pharmaceuticals utilizes a structure-based drug-design platform known as Contour to develop its compounds, targeting large markets with chronic conditions, including chronic kidney disease and atherosclerosis. In 2016, Vitae became a subsidiary of Allergan plc.

Satiety, Inc. is a medical device company focused on the development of less invasive devices for the treatment of obesity. Obesity is a global health problem, affecting 70 million people in the U.S. and 300 million worldwide, and growth of which is causing increases in obesity-related diseases such as diabetes, high blood pressure and cardiovascular disease. Obesity surgery has been shown to be the only long-term effective means of weight loss for morbidly obese patients. Satiety, Inc. was founded in 2000 through a collaboration of medical device incubators Thomas Fogarty Engineering and The Foundry, and is headquartered in Palo Alto, California.

AVEO Oncology is a biopharmaceutical company that specializes in developing and commercializing targeted therapies for oncology and other unmet medical needs. The company is known for its lead product, FOTIVDA (tivozanib), an oral vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitor used in the treatment of renal cell carcinoma (RCC). AVEO has completed a Phase III trial for tivozanib and is exploring its use in combination with the immune checkpoint inhibitor Opdivo. Additionally, the company is developing other therapeutic candidates, including Ficlatuzumab, an antibody for various cancers, and AV-203, a monoclonal antibody for esophageal cancer, which has completed Phase I trials. AVEO's preclinical pipeline includes promising products aimed at treating conditions such as cachexia and pulmonary arterial hypertension. Headquartered in Boston, Massachusetts, the company was founded in 2001 and has established collaborations with various pharmaceutical firms to enhance its development efforts.

CymaBay Therapeutics, Inc., established in 1988 and headquartered in Newark, California, is a clinical-stage biopharmaceutical company dedicated to developing therapies for liver diseases and other chronic conditions with significant unmet medical needs. Its primary focus is on seladelpar (MBX-8025), a selective agonist of peroxisome proliferator activated receptor delta, currently in Phase II trials for treating primary biliary cholangitis, sclerosing cholangitis, and nonalcoholic steatohepatitis. Additionally, the company is developing MBX-2982, an orally-active G protein-coupled receptor agonist targeting gut/liver diseases, and CB-001, a preclinical-stage product candidate for treating gut/liver disease using omega-3 fatty acids. CymaBay has partnerships with Janssen Pharmaceuticals and DiaTex for developing therapies for metabolic diseases and gout, respectively.

Surface Logix is a drug development company specializing in the creation of innovative small molecule drugs aimed at treating metabolic and cardiovascular diseases. Utilizing its expertise in biophysical chemistry, the company develops new chemical entities that demonstrate significantly enhanced pharmacokinetic and pharmacodynamic properties compared to existing market leaders. Surface Logix focuses on targeting specific tissues and organ systems, including the gastrointestinal and cardiovascular systems, and has various ongoing programs addressing a range of metabolic and cardiovascular conditions.

Vontu specializes in data loss prevention software solutions for organizations, focusing on the protection of sensitive information across various data repositories. The company offers two key products: Storage Data Loss Prevention and Endpoint Data Loss Prevention. The Storage Data Loss Prevention solution identifies and safeguards confidential data located on file servers, databases, and platforms such as Microsoft SharePoint and Documentum, among others. Meanwhile, the Endpoint Data Loss Prevention solution protects confidential data residing on laptops and desktops, preventing unauthorized copying to devices like USB drives, CDs, and local drives. Through these offerings, Vontu aims to help organizations secure their critical information assets from potential breaches and data loss incidents.

Amphora Discovery Corporation is a biotechnology company based in Durham, North Carolina, founded in 2001. The company specializes in providing integrated services to the pharmaceutical industry, focusing on pathway-based drug discovery. Its offerings include in vitro assay protocols, high-throughput screening, compound profiling, custom assay development, and enzymology services. Amphora's lead generation platform is recognized for its precision and data quality, facilitating the development of proprietary clinical entities targeting oncology, inflammation, metabolic diseases, and neurological disorders. The company serves a diverse clientele that includes pharmaceutical and biopharmaceutical firms, emerging biotechnology companies, and research foundations. Among its most advanced compounds are preclinical candidates specifically designed as inhibitors for AKT1 and p38, demonstrating Amphora's commitment to advancing drug discovery solutions. As of 2008, Amphora operates as a subsidiary of Nanosyn Inc.

CipherMax, Inc. provides enterprise-class storage security solutions for securing information assets and achieving compliance with government regulations. The company offers CipherMax CM140T, a storage security system for tapes that provides line-speed encryption processing and centralized security administration solutions for legacy and LTO-4 drives. It also provides CipherMax CM180D, a compact storage security system to integrate high performance encryption with SAN access control and 16-ports connectivity for fabric-based protection of sensitive data on disks; CipherMax CM250, an enterprise storage security system to integrate into existing SANs with 64-ports connectivity; and CipherMax CM500, a system for securing disk-based stored data for enterprise data centers with high port count storage environments. In addition, it offers SANCruiser, a secure storage management software for the management of systems, SAN, and security functions in an enterprise storage environment; and KeyCruiser, a key lifecycle management system for the secure administration of data encryption keys. CipherMax, Inc. was formerly known as MaXXan Systems, Inc. and changed its name to CipherMax, Inc. in 2007. The company was founded in 2000 and is based in San Jose, California.

Ironwood Pharmaceuticals is a specialty pharmaceutical company focused on gastroenterology therapies. Its lead product is linaclotide, marketed as LINZESS in the United States and CONSTELLA elsewhere, for adults with irritable bowel syndrome with constipation and chronic idiopathic constipation. The company is advancing other GI candidates, including MD-7246, an oral non-opioid pain reliever for abdominal GI pain, and IW 3718, a gastric-retentive bile acid sequestrant in Phase III for GERD. Ironwood pursues collaborations to expand linaclotide’s reach in North America, China, Hong Kong, Macau, and Japan, with agreements involving Allergan and AstraZeneca and a license with Astellas for Japan. It operates an independent subsidiary, Microbia, that develops bioprocesses for pharmaceuticals and related industries. Founded in 1998, Ironwood is headquartered in Massachusetts.

Veridiem Inc is an enterprise software company based in Maynard, Massachusetts, specializing in marketing resource management solutions. The company provides a comprehensive suite of applications focused on marketing analysis, operational efficiency, and optimization tailored for the automotive, consumer packaged goods, and financial industries. In addition to its software offerings, Veridiem also delivers implementation, professional, training, and support services to ensure effective utilization of its solutions.

Infinera Corporation is a global provider of optical transport networking equipment, software, and services, headquartered in Sunnyvale, California. The company specializes in photonic integration technology, offering a diverse portfolio that includes modular platforms, coherent optical transport systems, and packet-optical transport solutions. Its products, such as the Infinera Groove series and 7300 series, cater to various transport network applications, enabling high-capacity data transmission and management. Infinera's digital transport node system incorporates advanced technology for digital processing of network traffic. The company also provides a range of support services, including technical support, installation, and professional services. Infinera's customer base consists of telecommunications service providers, internet content providers, cable operators, research institutions, large enterprises, and government entities, all of whom rely on its solutions for efficient optical networking. Founded in 2000, Infinera continues to innovate in the field of optical networking, enhancing the capabilities of global communications infrastructure.

Intarcia Therapeutics, Inc. is a biopharmaceutical company focused on developing therapies for chronic conditions requiring long-term treatment. The company is known for its innovative drug delivery platform, DUROS, which stabilizes and administers therapeutic proteins and peptides effectively. Among its key products is ITCA 650, currently in phase 3 clinical trials for type 2 diabetes, designed to provide patients with continuous dosing of an incretin mimetic therapy. Intarcia also explores treatments for obesity and other chronic disorders. Established in 1995 and headquartered in Boston, Massachusetts, Intarcia operates a manufacturing facility in Hayward, California, and a research and development center in Durham, North Carolina. The company was previously known as BioMedicines, Inc. before adopting its current name in 2004.

White Amber provides non-workforce management solutions. It was founded in 1977 and is headquartered in New York, United States.

Vocera Communications, Inc. specializes in providing secure and integrated communication and workflow solutions tailored for mobile workers across various sectors, including healthcare, hospitality, retail, energy, and education. The company’s offerings enhance communication and operational efficiency by integrating with existing clinical systems, such as electronic health records and nurse call systems. Vocera's product suite includes the Vocera Communication and Workflow System, which connects various communication devices, including hands-free and voice-controlled options, and the Vocera Care Experience software, designed to improve patient care quality and streamline manual tasks. Additionally, Vocera operates the Experience Innovation Network, collaborating with healthcare organizations to develop innovative solutions that improve patient and care team experiences. The company, founded in 2000 and headquartered in San Jose, California, serves approximately 1,700 healthcare facilities globally, including hospitals and clinics, and distributes its products through direct sales, resellers, and distributors.

2Wire develops hardware and software solutions for telecommunications companies. Their platform includes residential gateways, modems, set-top boxes, and management systems, enabling providers to deliver high-speed internet, voice, and media services to consumers.

Healinx is a unique medical relationship management application service provider (ASP). Our mission is to increase communication and the satisfaction level between patients and their doctors, while enhancing physician practice efficiency and profitability. By providing a Web-based channel that links patients directly to their personal doctors, Healinx allows patients to communicate with their doctors or access their medical information anytime -- from anywhere. In addition, patients can receive personalized health information from their doctors. The Healinx customized Internet messaging enables doctors and patients to communicate online with state of the art security and privacy. In addition, the Healinx channel includes a set of tools for electronic prescriptions and preventive care.

RelayHealth is a provider of online healthcare communication services that facilitates secure and convenient information exchange among various healthcare stakeholders, including patients, providers, pharmacies, payors, and pharmaceutical manufacturers. The company offers a range of services such as ePrescribing, online refills, access to lab results, reimbursable online visits, and online bill payments. By enabling consistent connectivity among medical companies, doctors, and patients, RelayHealth aims to streamline interactions within the healthcare system. This connectivity ultimately contributes to improved patient care, faster access to necessary services, reduced costs, and enhanced operational efficiency for healthcare providers.

Genband is a global provider of high-performance IP gateways and session border controllers, which are integral components in fixed and mobile networks worldwide. The company's products facilitate secure communication by evolving and enhancing networks' capabilities.