Venrock

Venrock is a venture capital firm that was established in 1969 as the investment arm of the Rockefeller family. The firm focuses primarily on technology and healthcare sectors, partnering with entrepreneurs to build successful and lasting companies. Over the years, Venrock has invested in a diverse range of notable portfolio companies, which include industry leaders in various fields. Its commitment to fostering innovation and supporting talented founders has positioned Venrock as a key player in the venture capital landscape.

Brian Ascher

Partner

Nick Beim

Partner

Racquel Bracken

Partner

Steven Goldby

Partner

Todd Graham

Vice President

Ken Greenberg

Investor

Manjinder Kandola

Investor

Mariana Mihalusova

Vice President

David Pakman

Partner

Camille Samuels

Partner

Ganesh Srinivasan

Partner

Ganesh Srinivasan

Partner

Mike Tyrrell

General Partner

Andy Wardle

Investor

Past deals in Series D

RefleXion Medical

Series D in 2020
RefleXion Medical Inc. is a medical equipment company specializing in the development of biologically-guided radiotherapy systems for cancer treatment. Its flagship innovation, the RefleXion X1 machine, is designed to deliver advanced radiation therapies such as stereotactic body radiotherapy (SBRT) and stereotactic radiosurgery (SRS). The company's biologically-guided radiotherapy (BgRT) technology utilizes positron-emission tomography (PET) imaging data to allow tumors to continuously signal their location during treatment, enabling the possibility of treating multiple tumors in a single session, especially in cases of metastasized cancers. This real-time adaptation to the biological characteristics of tumors represents a significant advancement in radiation oncology. RefleXion Medical, incorporated in 2009 and based in Hayward, California, has established strategic partnerships with Telix Pharmaceuticals Limited and HealthMyne Inc. to further its mission in cancer treatment innovation.

Kyruus

Series D in 2020
Kyruus, Inc. is a Boston-based company that develops web-based software solutions aimed at optimizing physician networks for hospitals, health systems, and life science companies. Founded in 2010, Kyruus offers a suite of analytically driven products designed to enhance provider search and scheduling, ensuring that patients are matched with the most suitable healthcare providers. Key offerings include Kyruus Passport, which allows physicians to track their activity and productivity, and Kyruus Profiles, which enables administrators to analyze physician performance metrics. Additionally, the company provides Kyruus MDSeekyr, a platform for identifying high-value providers, and Kyruus Insight Reports, which help executives evaluate network activity and performance trends. By leveraging a proprietary provider data management platform, Kyruus enhances patient engagement and aligns provider supply with patient demand, ultimately improving the overall healthcare experience. Kyruus also maintains offices in San Francisco and New York.

Inscripta

Series D in 2019
Inscripta, Inc. is a gene editing technology company based in Boulder, Colorado, with additional offices in Pleasanton and San Diego, California. Founded in 2015, the company is focused on developing advanced CRISPR enzymes, specifically its proprietary MADzymes, to facilitate precision gene editing. Inscripta has created the first benchtop platform for scalable digital genome engineering, which includes an instrument, consumables, software, and assays that enable fully automated workflows for massively parallel editing of single cells. This innovative platform aims to empower scientists by overcoming existing technical and licensing challenges in gene editing research. By providing tools that allow for the generation of extensive libraries of designer proteins and genome variants, Inscripta supports researchers in designing, engineering, and evaluating genetic modifications with unprecedented ease and efficiency.

Dstillery

Series D in 2019
Dstillery, Inc. is a digital intelligence platform that specializes in providing marketing solutions for brands and media partners. Founded in 2008 and based in New York City, the company offers a range of services aimed at enhancing brand awareness, consideration, and customer retention. Dstillery employs artificial intelligence to analyze consumer data, enabling brands to optimize their advertising strategies across mobile, desktop, and video channels. One of its notable products, ID-free®, offers a privacy-safe approach to behavioral targeting, ensuring comprehensive audience reach. The platform also features Dscover Maps, a geospatial insights tool that helps clients understand market composition based on geography. Dstillery's ongoing innovation is reflected in its numerous patents for advanced AI technology, which supports its mission to empower brands and agencies in executing high-performing programmatic advertising campaigns.

ShockWave Medical

Series D in 2018
ShockWave Medical, Inc. is a medical device company based in Santa Clara, California, focused on developing and commercializing intravascular lithotripsy technology to treat calcified plaque associated with peripheral vascular, coronary vascular, and heart valve diseases. The company offers a range of catheters, including M5 for above-the-knee peripheral artery disease, C2 for coronary artery disease, and S4 for below-the-knee peripheral artery disease. Its Lithoplasty™ technology utilizes sonic pressure waves to facilitate the treatment of rigid vascular and valvular lesions, allowing for improved angioplasty outcomes and reduced reliance on stents. This innovative approach enhances vessel preparation before procedures such as drug eluting balloon placement and trans-catheter aortic valve replacement. ShockWave Medical serves a diverse clientele, including interventional cardiologists, vascular surgeons, and interventional radiologists, through a network of sales representatives, managers, and distributors across the United States and Europe. Incorporated in 2009, the company is committed to transforming cardiovascular care and improving patient outcomes.

CTERA

Series D in 2018
CTERA develops a cloud storage platform that allows enterprise IT departments to offer secure file services across various cloud environments. Its Enterprise File Services Platform serves as a private cloud IT-as-a-Service solution, facilitating the storage, syncing, sharing, protection, and governance of data across endpoints, remote offices, and servers. By replacing traditional storage and backup systems with a cloud file system that utilizes software-defined file services over object storage, CTERA enables organizations to support modern remote work. This allows distributed offices and remote workers to store, access, and collaborate on files efficiently from any device or location, making it a trusted solution for Fortune 100 companies and leading service providers.

Salsify

Series D in 2018
Salsify is an e-commerce software startup based in Boston, Massachusetts, founded in 2012 by Jason Purcell, Jeremy Redburn, and Rob Gonzalez. The company provides a comprehensive platform known as Commerce Experience Management (CommerceXM), which integrates Product Experience Management tools—including Product Information Management (PIM), Digital Asset Management (DAM), and an Experience Builder—with essential commerce functionalities. This platform is designed to facilitate sales across various channels, including retailers, distributors, marketplaces, social commerce, and direct-to-consumer (D2C) sites. By offering these tools, Salsify aims to enhance brand visibility and performance on digital shelves, helping businesses optimize their product presentation and inventory management to drive online sales effectively.

Hua Medicine

Series D in 2018
Hua Medicine is a clinical-stage drug development company based in Pudong, China, specializing in innovative therapies for diabetes and central nervous system (CNS) disorders. Founded in 2009 by experienced professionals in the pharmaceutical industry, the company is advancing its lead product, Dorzagliatin, an oral medication for Type 2 diabetes, which has reached the NDA enabling stage and is currently undergoing two Phase 3 trials in drug-naive and metformin-treated patients in China. Additionally, Hua Medicine is exploring mGLUR5, a novel drug candidate aimed at treating levodopa-induced dyskinesia in Parkinson's disease. The company has secured funding from prominent international venture capital firms and has in-licensed global rights to its diabetes drug, positioning itself as a key player in the treatment landscape for these chronic conditions.

Tricida

Series D in 2017
Tricida, Inc. is a late-stage pharmaceutical company based in South San Francisco, California, dedicated to the development and commercialization of its lead drug candidate, TRC101. This non-absorbed, orally-administered polymer is designed to treat metabolic acidosis, a condition often associated with chronic kidney disease (CKD). Metabolic acidosis can contribute to the progression of CKD and is linked to various health issues such as muscle wasting, loss of bone density, and increased mortality risk. Tricida has successfully completed a Phase 3, double-blind, placebo-controlled trial of TRC101, aiming to provide an effective treatment option for patients suffering from this condition. The company was founded in 2013 and is focused on addressing the unmet medical needs of individuals with CKD.

VeloCloud

Series D in 2017
VeloCloud Networks, Inc. is a provider of cloud-based networking services specializing in software-defined wide area networking (SD-WAN). The company focuses on improving network performance over various connections, including private, broadband Internet, and LTE links. VeloCloud's SD-WAN solutions enable enterprises to automate deployment and enhance connectivity to cloud and enterprise applications through a choice of public, private, or hybrid cloud networks. Their offerings include branch office appliances, optional data center appliances, and software-defined control and automation, facilitating efficient virtual services delivery. By optimizing access to cloud services and private data centers, VeloCloud empowers clients with policy-based access to critical applications, making it a notable player in the increasingly distributed enterprise landscape.

Dynamic Signal

Series D in 2016
Dynamic Signal Inc. is an employee communication and engagement platform that enhances the connection between organizations and their employees. Founded in 2010 and based in San Bruno, California, the company specializes in employee advocacy programs designed to boost sales, increase brand awareness, and improve operational efficiency while fostering higher employee engagement. The platform facilitates timely and relevant communication, ensuring that employees receive essential enterprise signals across various channels and devices. Dynamic Signal offers a range of services, including influencer recruiting, collaboration support, member rewards, and account management. Its solutions are utilized by hundreds of major enterprises worldwide, including many Fortune 500 companies, to empower employees and drive productivity through effective advocacy.

Shape Security

Series D in 2016
Shape Security, Inc. specializes in cybersecurity solutions aimed at protecting web and mobile applications from automated cyber-attacks. Established in 2011 and headquartered in Santa Clara, California, with additional offices in Sydney and London, the company offers products such as ShapeShifter Elements, which enforces real-time security measures, and Shape Protection Manager, a cloud-based management tool for its services. Shape Security has successfully prevented over $1 billion in fraud losses for a diverse range of clients, including major retailers, financial institutions, airlines, and government agencies. Its AI-powered technology effectively mitigates risks associated with fraud, chargebacks, and unauthorized transactions, helping organizations maintain customer trust and protect their reputations against the threats posed by criminal activity.

PowerVision

Series D in 2016
PowerVision, Inc. is a company that specializes in the development of innovative intraocular lenses aimed at restoring vision for individuals suffering from presbyopia and cataracts. Founded in 2002 and based in Belmont, California, PowerVision has created the FluidVision accommodating intraocular lens, which utilizes a unique fluid-controlled mechanism to mimic the natural function of a healthy eye. This technology allows users to dynamically adjust their focus for clear vision at all distances, potentially liberating millions from the need for glasses or other vision correction methods. The FluidVision lens is designed to meet the clinical and lifestyle needs of patients, offering a significant advancement in vision correction surgery. PowerVision's approach addresses the visual impairments faced by over 20 million people in the United States with cataracts and more than 90 million individuals affected by presbyopia, particularly those in their 40s and 50s.

Dollar Shave Club

Series D in 2015
Dollar Shave Club is a lifestyle brand and e-commerce company that invents and delivers smart, affordable products to make lives easier. Through an exclusive R&D process that includes botanicals and chemists, the company makes all its own products at affordable prices. Dollar Shave Club was founded in 2012 and is based in Santa Monica, California.

Cloudflare

Series D in 2015
Cloudflare, Inc. is a San Francisco-based software company that specializes in web performance and security services for businesses globally. It operates a cloud platform that integrates various network services, including security solutions such as Cloud Firewall, Bot Management, and Distributed Denial of Service protection. The company enhances website performance through its Content Delivery Network (CDN) and intelligent routing, while also providing optimization tools for content and images. Furthermore, Cloudflare offers reliability solutions like Load Balancing and DNS services, alongside security features aimed at protecting internal resources through Zero Trust Security and Secure Web Gateway. Its consumer offerings include a DNS resolver and a virtual private network (VPN) designed to secure mobile traffic. Cloudflare serves diverse industries, including technology, healthcare, financial services, and government, and was founded in 2009.

CytomX Therapeutics

Series D in 2015
CytomX Therapeutics is an oncology-focused biopharmaceutical company based in South San Francisco, California. The company specializes in developing proteolytically-activated antibody therapeutics using its proprietary Probody technology platform. This innovative approach aims to create cancer immunotherapies that enhance targeting of tumor cells while minimizing effects on healthy tissues. CytomX's clinical-stage product candidates include CX-072, which targets programmed cell death ligand 1; CX-2009, a drug conjugate against CD166; and BMS-986249, a CTLA-4 Probody therapeutic for metastatic melanoma, among others. The company has established strategic collaborations with several major pharmaceutical companies, including AbbVie, Amgen, and Bristol-Myers Squibb, to further the development of its Probody therapeutics. Founded in 2008, CytomX is dedicated to providing patients with more effective and less toxic treatment options for cancer and inflammatory diseases.

Regenxbio

Series D in 2015
REGENXBIO Inc. is a clinical-stage biotechnology company specializing in gene therapy aimed at addressing genetic defects and enabling cells to produce therapeutic proteins and antibodies. The company utilizes its proprietary NAV Technology Platform, which involves recombinant adeno-associated virus vectors for gene delivery. REGENXBIO’s lead candidate, RGX-314, is currently in Phase I/IIa clinical trials for the treatment of wet age-related macular degeneration. Additional product candidates under development include RGX-121 for mucopolysaccharidosis type II, RGX-111 for mucopolysaccharidosis type I, RGX-181 for late infantile neuronal ceroid lipofuscinosis type II, and RGX-501 for homozygous familial hypercholesterolemia. Beyond its own product candidates, REGENXBIO also licenses its NAV Technology Platform to other biotechnology and pharmaceutical companies and has a collaboration agreement with Neurimmune AG to develop vectorized antibodies for neurodegenerative diseases. Founded in 2008 and headquartered in Rockville, Maryland, the company was previously known as ReGenX Biosciences, LLC before rebranding in 2014.

Dataminr

Series D in 2015
Dataminr is an AI platform that detects the earliest signs of high-impact events and emerging risks from publicly available information. It discovers, distills, and delivers alerts from the increasingly diverse and complex landscape of publicly available information including social media, blogs, information sensors, and the dark web, ensuring that businesses have the knowledge they need to act with confidence.

Ascendis Pharma

Series D in 2014
Ascendis Pharma A/S is a biopharmaceutical company based in Hellerup, Denmark, focused on developing prodrug therapies to address unmet medical needs. Leveraging its innovative TransCon technology platform, the company aims to create superior prodrugs across various drug classes, including proteins, peptides, and small molecules. Its pipeline includes TransCon growth hormone, which has completed Phase III clinical trials for treating growth hormone deficiency in children, and TransCon parathyroid hormone, currently in Phase II trials for hypoparathyroidism. Additionally, TransCon CNP is in Phase II development for achondroplasia. Ascendis Pharma also explores preclinical studies in oncology and employs strategic collaborations to enhance its product development, aiming for systemic and localized drug delivery. The company primarily operates in North America, with additional activities in Europe and China.

Personal Capital

Series D in 2014
Personal Capital Corporation is a digital wealth management company that offers financial advisory services and software designed to help individuals manage their finances effectively. Founded in 2009 and based in Redwood Shores, California, the company provides a suite of tools that allows users to monitor their income, spending, and investment performance in one place. With over 2.5 million customers, Personal Capital combines advanced software capabilities with personalized guidance from registered investment advisors, helping clients analyze cash flow, assess risks, and develop customized financial strategies. The company aims to transform financial management through technology, enabling individuals to gain a comprehensive understanding of their financial situations.

PowerVision

Series D in 2014
PowerVision, Inc. is a company that specializes in the development of innovative intraocular lenses aimed at restoring vision for individuals suffering from presbyopia and cataracts. Founded in 2002 and based in Belmont, California, PowerVision has created the FluidVision accommodating intraocular lens, which utilizes a unique fluid-controlled mechanism to mimic the natural function of a healthy eye. This technology allows users to dynamically adjust their focus for clear vision at all distances, potentially liberating millions from the need for glasses or other vision correction methods. The FluidVision lens is designed to meet the clinical and lifestyle needs of patients, offering a significant advancement in vision correction surgery. PowerVision's approach addresses the visual impairments faced by over 20 million people in the United States with cataracts and more than 90 million individuals affected by presbyopia, particularly those in their 40s and 50s.

Smartling

Series D in 2014
Smartling is a language service and technology provider based in New York that specializes in content localization for businesses seeking to expand into international markets. Founded in 2009 by Jack Welde and Andrey Akselrod, Smartling offers a Translation Management Platform that facilitates the translation and deployment of multilingual websites, mobile applications, and business documents across various digital platforms. This cloud-based enterprise translation software allows brands to enhance their global presence and deliver authentic brand experiences. Notable clients include British Airways, Uber, Spotify, and Hasbro, all of which utilize Smartling's solutions to engage more effectively with diverse customer bases.

Phononic

Series D in 2014
Phononic is a growth stage, semiconductor hardware company commercializing solid-state heat pumps and fully integrated systems that displace compressors, heat sinks, and fans for electronics cooling; residential and commercial refrigeration; and climate control. The company’s disruptive approach combines high-performance solid-state heat pumps integrated into a manufacturing-friendly systems architecture that realizes products that are smart, sustainable, and solid state-driven.

PowerVision

Series D in 2014
PowerVision, Inc. is a company that specializes in the development of innovative intraocular lenses aimed at restoring vision for individuals suffering from presbyopia and cataracts. Founded in 2002 and based in Belmont, California, PowerVision has created the FluidVision accommodating intraocular lens, which utilizes a unique fluid-controlled mechanism to mimic the natural function of a healthy eye. This technology allows users to dynamically adjust their focus for clear vision at all distances, potentially liberating millions from the need for glasses or other vision correction methods. The FluidVision lens is designed to meet the clinical and lifestyle needs of patients, offering a significant advancement in vision correction surgery. PowerVision's approach addresses the visual impairments faced by over 20 million people in the United States with cataracts and more than 90 million individuals affected by presbyopia, particularly those in their 40s and 50s.

Aria Systems

Series D in 2013
Aria Systems provides a cloud-based monetization platform designed to assist subscription and usage-based businesses in effectively managing their revenue streams. The company offers an agile billing system that enables enterprises to capitalize on customer-driven events, referred to as revenue moments. By facilitating active customer engagement and the rapid development of new products and services, Aria's comprehensive platform allows global brands to enter the market more quickly and diversify their offerings. The platform also includes on-demand billing software, marketing intelligence tools, and customer lifecycle management services tailored for software-as-a-service (SaaS) companies, game developers, and telecommunications providers. Through these capabilities, Aria Systems aims to support long-term business growth and enhance customer satisfaction, retention, and lifetime value.

Martini Media Network

Series D in 2013
Martini Media Network, Inc. is a digital media and content platform based in San Francisco, California, that focuses on engaging affluent audiences through tailored brand campaigns. Established in 2007, the company specializes in delivering media solutions that integrate content, videos, and social features across niche sites frequented by its target demographic. Martini Media operates invitation-only platforms centered on business and lifestyle categories, offering a range of services including advertising, publishing, and storytelling. By partnering with brands and agencies, the company crafts customized programs designed to meet specific marketing goals and effectively reach influential consumers. As of June 2015, Martini Media operates as a subsidiary of Evolve Media, LLC.

Atrenta

Series D in 2013
Atrenta specializes in providing software solutions for the semiconductor and consumer electronics industries, with a focus on enhancing design efficiency through its SpyGlass Predictive Analysis platform. This patented technology offers early insights into the performance, power, and area requirements of complex system on chips (SoCs), which are critical to the modern consumer electronics landscape. By identifying structural, coding, and consistency issues in register transfer language (RTL), SpyGlass enables design engineers to optimize testability and reduce risks and costs prior to the deployment of traditional electronic design automation (EDA) tools. With a user base of over two hundred companies and thousands of design engineers globally, Atrenta positions itself as a vital resource for navigating the complexities of SoC design, ensuring a more streamlined and effective implementation process.

Achaogen

Series D in 2013
Achaogen is a clinical stage biopharmaceutical company focused on the discovery and development of broad-spectrum antibiotics to treat multi-drug resistant bacterial infections. The company's most advanced drug candidate, ACHN-490, has demonstrated a positive safety and dosing profile in Phase 1 clinical testing and displayed broad spectrum efficacy in preclinical studies against systemic infections caused by multi-drug resistant (MDR) Gram-negative bacteria (e.g., E. coli, K. pneumoniae, and P. aeruginosa) and MRSA. In addition, the company is pursuing preclinical programs in several other areas of interest to combat the global emergence of bacterial resistance.

AppNexus

Series D in 2013
AppNexus Inc. is a technology company that specializes in a cloud-based platform designed to enhance programmatic online advertising. Founded in 2007 and headquartered in New York City, the company provides tools for both advertisers and publishers to maximize campaign performance and revenue. Its offerings include a comprehensive digital advertising delivery platform, the AppNexus Publisher Suite for ad serving and campaign management, and PriceCheck, a header bidding solution for various ad formats. AppNexus also features an application platform that allows third-party vendors and existing clients to develop customized features. By leveraging data and machine learning, AppNexus aims to optimize the real-time buying and selling of digital advertising, catering to the needs of marketers, agencies, and publishers. The company operates as a subsidiary of Xandr, Inc., with additional offices located in the United States and internationally.

Transonic Combustion

Series D in 2012
Founded in 2006, Transonic Combustion's TSCi™ fuel injection systems provide global automotive manufacturers with high efficiency fuel delivery technology for their modern engine platforms. The company is backed by Venrock, Khosla Ventures, Rustic Canyon, and Saints Capital. Transonic Combustion is headquartered in Camarillo, Calif.

Castlight Health

Series D in 2012
Castlight is on a mission to make it as easy as humanly possible for people to navigate the healthcare system, and live happier, healthier, more productive lives. They as a leader in healthcare navigation, we provide a world-class digital platform with a team of clinical, and benefits experts to help members easily connect, and engage with the right programs and care, at the right time. Castlight partners with companies, and health plans to transform employee, and member benefits into one comprehensive health, and wellbeing experience to deliver better health outcomes, and maximize returns on healthcare investments.

Cerulean Pharma

Series D in 2011
Cerulean Pharma Inc. is a privately-held biopharmaceutical company specializing in the development of innovative nanotechnology-based therapeutics aimed at treating oncology, cardiovascular, autoimmune, and inflammatory diseases. The company focuses on nanoparticle-drug conjugates that target tumors, reduce toxicity, and facilitate therapeutic combinations. Among its notable products is Ovaprene, a contraceptive designed to offer hormone-free protection for multiple weeks. Cerulean has established a distinguished management team and advisory board, drawing from extensive experience in product development and scientific innovation from renowned institutions and companies in the biopharmaceutical sector.

Intuity Medical

Series D in 2011
Intuity Medical, Inc. is a company focused on developing innovative blood glucose monitoring systems for diabetes management. Founded in 2002 and headquartered in Fremont, California, Intuity Medical is known for its POGO Automatic Blood Glucose Monitoring System, which is the first FDA-cleared automatic device that integrates lancing, blood collection, and analysis into a single 10-test cartridge. This system offers a convenient and discreet solution for individuals who need to regularly monitor their blood glucose levels, making it easier for millions of patients to manage their diabetes effectively. The company was previously named Rosedale Medical, Inc. before rebranding in June 2007.

Gazelle

Series D in 2011
Gazelle is an e-commerce platform that specializes in buying and selling used electronic devices, including smartphones, tablets, laptops, and desktops. Founded in 2006 and headquartered in Boston, Massachusetts, with operations in Louisville, Kentucky, the company provides a convenient service for consumers looking to purchase affordable electronics. Gazelle buys pre-owned devices, inspects and certifies them, and then resells them, making it easier for consumers to acquire quality gadgets at lower prices. The platform also promotes the recycling of electronics, contributing to sustainable practices in the tech industry.

Nanosys

Series D in 2010
Nanosys, Inc. is a technology company based in Milpitas, California, specializing in the development and manufacturing of quantum dot technology aimed at enhancing the viewing experience in various display applications. Founded in 2001, Nanosys produces Quantum Dot Concentrate materials, quantum dot nanomaterials, and Quantum Dot Enhancement films, which are utilized by industrial supply chain partners in consumer electronics such as televisions, tablets, smartphones, and automotive interiors. The company's quantum dot technologies enable displays to achieve brighter images with a wider color range and improved power efficiency. These technologies are compatible with various display types, including LED-LCDs, OLEDs, and micro-LEDs. By 2020, Nanosys' proprietary technology had been integrated into over 20 million devices across more than 400 unique products, significantly improving the realism and immersion of visual experiences for consumers.

Zeltiq Aesthetics

Series D in 2010
Zeltiq Aesthetics, founded in 2005 and headquartered in Pleasanton, California, is a medical technology company focused on developing non-invasive solutions for the reduction of unwanted fat tissue. The company's flagship product, the CoolSculpting system, employs a patented technology known as Cryolipolysis, which utilizes controlled cooling to selectively target and eliminate fat cells while preserving surrounding skin and tissue. This FDA-cleared treatment provides a non-surgical option for individuals seeking to reduce stubborn fat bulges. Zeltiq distributes its products through a direct sales force and a network of distributors, catering primarily to dermatologists, plastic surgeons, and aesthetic specialists across North America, Europe, the Asia-Pacific, and Latin America. The company was previously known as Juniper Medical, Inc. before rebranding in 2007. As of 2017, Zeltiq operates as a subsidiary of Allergan plc.

Intuity Medical

Series D in 2010
Intuity Medical, Inc. is a company focused on developing innovative blood glucose monitoring systems for diabetes management. Founded in 2002 and headquartered in Fremont, California, Intuity Medical is known for its POGO Automatic Blood Glucose Monitoring System, which is the first FDA-cleared automatic device that integrates lancing, blood collection, and analysis into a single 10-test cartridge. This system offers a convenient and discreet solution for individuals who need to regularly monitor their blood glucose levels, making it easier for millions of patients to manage their diabetes effectively. The company was previously named Rosedale Medical, Inc. before rebranding in June 2007.

Boston Power

Series D in 2009
Boston Power specializes in developing advanced lithium-ion battery technology aimed at enhancing energy storage solutions. The company's Sonata technology platform is designed to charge faster, last longer, and provide superior performance and safety compared to existing market options. This innovative technology is applicable across various consumer electronic devices, including laptops, PDAs, and mobile phones, as well as in battery electric and plug-in hybrid electric vehicles, and utility energy storage applications. Boston Power's focus on improving the quality and safety of energy storage positions it as a significant player in the evolving landscape of portable power systems.

Awarepoint

Series D in 2008
Awarepoint Corporation, established in 2002 and based in San Diego, California, specializes in providing cloud-based real-time locating systems (RTLS) tailored for the healthcare sector and other industries such as manufacturing and retail. The company's solutions enhance operational efficiency by enabling organizations to track assets and streamline workflows, thus addressing critical challenges in asset management, compliance, and patient throughput. Awarepoint integrates software, technology, and managed services into a cohesive platform, allowing healthcare providers to optimize their existing IT investments. Additionally, the company offers a Temperature Monitoring System that helps medical facilities comply with guidelines for vaccine storage. As a leader in workflow automation and tracking solutions, Awarepoint supports healthcare professionals in achieving improved clinical and financial outcomes.

Kineto Wireless

Series D in 2008
Kineto Wireless is a privately held company that specializes in fixed-mobile convergence technology, aiding mobile operators in their transition to IP-based services. The company offers solutions designed to enhance the competitiveness of mobile operators against over-the-top service providers. Key offerings include Smart Comms, which leverages Rich Communications Suite technology to help operators brand and monetize their voice and messaging services, and Smart Wi-Fi, which transforms existing Wi-Fi access points into virtual femtocells on operators' networks. These technologies enable smartphone users to access mobile services over Wi-Fi, including voice and messaging. Kineto collaborates with various industry partners such as HTC Corporation, Huawei, and T-Mobile USA to deliver its innovative solutions.

DATAllegro

Series D in 2008
DATAllegro provides integrated data warehousing services.

GENBAND

Series D in 2008
GENBAND is a global supplier of IP gateways, session border controllers, and FMC security solutions that enhance the performance and security of fixed and mobile communication networks. The company specializes in developing IP multimedia applications and infrastructure products aimed at transforming the speed and quality of communication. GENBAND's software solutions facilitate seamless connectivity and rapid deployment of services for service providers, enterprises, and systems integrators. By integrating real-time contextual communications into business and consumer applications, GENBAND aims to improve productivity and user engagement across various workflows.

Imperva

Series D in 2008
Imperva, Inc. is a cybersecurity company based in Redwood Shores, California, that specializes in protecting critical business data and applications across cloud and on-premises environments. Founded in 2002, Imperva develops a range of security solutions, including its SecureSphere product line, which offers database, file, and web application security. The company’s services also include Incapsula, which provides cloud-based website security and distributed denial of service protection, as well as ThreatRadar for crowdsourced security intelligence. Additionally, CounterBreach safeguards enterprise data against loss from compromised users, and Imperva Camouflage Data Masking allows for the secure use of sensitive information in development and testing. Imperva serves various sectors, including finance, healthcare, retail, and telecommunications, through a network of distributors and resellers, while also offering ongoing support and professional services.

Digit Wireless

Series D in 2008
Digit Wireless, operates as a user interface innovation company. It offers Fastap keypad technology solutions that enable to discover, access, and use messaging, mobile data, and voice services. The company licenses its technology to mobile manufacturers and operators. Digit Wireless, Inc. was founded in 2000 and is headquartered in Burlington, Massachusetts with additional offices in Beijing, Shanghai, Hong Kong, London, and Seoul.

Vitae Pharmaceuticals

Series D in 2007
Vitae Pharmaceuticals is a clinical-stage biotechnology company based in Fort Washington, Pennsylvania, dedicated to discovering and developing novel small molecule drugs for diseases with significant unmet medical needs. Its pipeline includes VTP-43742, currently in Phase I clinical trials for autoimmune disorders such as psoriasis and multiple sclerosis; VTP-38543, in Phase IIa for atopic dermatitis; and BI 1147560, aimed at treating and preventing Alzheimer's disease. Additionally, the company is developing VTP-34072, which is in Phase II trials for type 2 diabetes, and VTP-38443 for acute coronary syndrome. Vitae Pharmaceuticals employs a structure-based drug-design platform, Contour, to create best-in-class compounds targeting large markets that include chronic kidney disease and atherosclerosis. Established in 2001, the company operates as a subsidiary of Allergan plc.

Satiety

Series D in 2007
Satiety, Inc. is a medical device company focused on the development of less invasive devices for the treatment of obesity. Obesity is a global health problem, affecting 70 million people in the U.S. and 300 million worldwide, and growth of which is causing increases in obesity-related diseases such as diabetes, high blood pressure and cardiovascular disease. Obesity surgery has been shown to be the only long-term effective means of weight loss for morbidly obese patients. Satiety, Inc. was founded in 2000 through a collaboration of medical device incubators Thomas Fogarty Engineering and The Foundry, and is headquartered in Palo Alto, California.

AVEO Oncology

Series D in 2007
AVEO Oncology is a commercial-stage biopharmaceutical company headquartered in Boston, Massachusetts, focused on developing and marketing targeted therapies for cancer. Its lead product, tivozanib, marketed as FOTIVDA, is an oral, once-daily vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitor used for treating renal cell carcinoma (RCC). The company has completed a Phase III trial of tivozanib and is investigating its use in combination with the immune checkpoint inhibitor Opdivo. Additionally, AVEO is developing Ficlatuzumab, an antibody targeting hepatocyte growth factor, currently in Phase II trials for several cancers, and AV-203, an anti-ErbB3 monoclonal antibody that has completed Phase I trials for esophageal cancer. The company also has preclinical products aimed at cachexia and pulmonary arterial hypertension. AVEO collaborates with various pharmaceutical companies to enhance its research and development efforts. Established in 2001, AVEO Oncology aims to address unmet medical needs in oncology through its innovative therapies.

Surface Logix

Series D in 2007
Surface Logix is a drug development company which uses its expertise in biophysical chemistry to create new small molecule drugs with significantly improved pharmacokinetic (PK) and pharmacodynamic (PD) properties compared with class leaders.

Amphora Discovery

Series D in 2005
Amphora Discovery Corporation is a biotechnology company based in Durham, North Carolina, that offers integrated services to the pharmaceutical industry. Founded in 2001 and now a subsidiary of Nanosyn Inc., the company specializes in pathway-based drug discovery services. Its offerings include in vitro assay protocols, throughput screening, compound profiling, custom assay development, and lead discovery and optimization programs. Amphora's lead generation platform is noted for its precision and data quality, leading to the development of proprietary clinical entities targeting oncology, inflammation, metabolic diseases, and neurological disorders. The company serves a diverse clientele, including pharmaceutical and biopharmaceutical companies, emerging biotechnology firms, and research foundations, with its most advanced compounds currently positioned as preclinical candidates in oncology and inflammation.

CipherMax

Series D in 2004
CipherMax, Inc. provides enterprise-class storage security solutions for securing information assets and achieving compliance with government regulations. The company offers CipherMax CM140T, a storage security system for tapes that provides line-speed encryption processing and centralized security administration solutions for legacy and LTO-4 drives. It also provides CipherMax CM180D, a compact storage security system to integrate high performance encryption with SAN access control and 16-ports connectivity for fabric-based protection of sensitive data on disks; CipherMax CM250, an enterprise storage security system to integrate into existing SANs with 64-ports connectivity; and CipherMax CM500, a system for securing disk-based stored data for enterprise data centers with high port count storage environments. In addition, it offers SANCruiser, a secure storage management software for the management of systems, SAN, and security functions in an enterprise storage environment; and KeyCruiser, a key lifecycle management system for the secure administration of data encryption keys. CipherMax, Inc. was formerly known as MaXXan Systems, Inc. and changed its name to CipherMax, Inc. in 2007. The company was founded in 2000 and is based in San Jose, California.

Ironwood Pharmaceuticals

Series D in 2004
Ironwood Pharmaceuticals is an entrepreneurial pharmaceutical company, engages in developing and marketing human medicines. It engages in developing a pipeline of clinical candidates in the areas of gastrointestinal diseases, cardiovascular diseases, pain, and inflammation. The company's operationally independent subsidiary, Microbia Inc., engages in developing and commercializing bioprocesses for use in pharmaceuticals, foods, and specialty and industrial chemicals. Ironwood Pharmaceuticals, Inc. was formerly known as Microbia, Inc. The company was founded in 1998 and is headquartered in Cambridge, Massachusetts.

Veridiem

Series D in 2004
Veridiem Inc is an enterprise software company that offers marketing resource management software. It also offers a suite of marketing analysis, operational, and optimization applications for companies in the automotive, consumer package goods, and financial industries. Veridiem Inc also offers implementation, professional, training, and support services. It is based in Maynard, Massachusetts.

Infinera

Series D in 2003
Infinera Corporation is a global supplier of optical transport networking equipment, software, and services, specializing in photonic integration technology. The company's product offerings include modular and sled-based platforms, coherent optical transport systems, and packet transport platforms designed for a variety of network applications. Infinera's digital transport node system leverages photonic integrated circuits to enable efficient management and processing of data, supporting high-capacity optical networks. Its solutions cater to telecommunications service providers, internet content providers, cable operators, and large enterprises, among others. In addition to hardware, Infinera provides a range of support services, including technical support, installation, and professional services, to ensure optimal performance of its products. Founded in 2000 and headquartered in Sunnyvale, California, Infinera has established itself as a leader in the optical networking space.

Intarcia Therapeutics

Series D in 2003
Intarcia Therapeutics, Inc. is a biopharmaceutical company focused on developing therapies for chronic conditions that require long-term management. The company is known for its innovative Medici Drug Delivery System, which facilitates subcutaneous delivery of therapies for diseases such as type 2 diabetes, obesity, and autoimmune disorders. Its lead product, ITCA 650, is currently in phase 3 clinical trials designed to provide sustained treatment for diabetes through a steady-state dosing system. Additionally, Intarcia's DUROS platform stabilizes and delivers therapeutic proteins and peptides, including devices aimed at treating conditions such as Hepatitis C. Founded in 1997 and originally named BioMedicines, the company rebranded to Intarcia Therapeutics in 2004. It is headquartered in Boston, Massachusetts, with a manufacturing facility in Hayward, California, and a research and development center in Durham, North Carolina.

White Amber

Series D in 2003
White Amber provides non-workforce management solutions. It was founded in 1977 and is headquartered in New York, United States.

Vocera Communications

Series D in 2003
Vocera Communications, Inc. specializes in providing secure and integrated communication and workflow solutions tailored for mobile workers across various sectors, including healthcare, hospitality, retail, energy, and education. The company’s offerings enhance communication and operational efficiency by integrating with existing clinical systems, such as electronic health records and nurse call systems. Vocera's product suite includes the Vocera Communication and Workflow System, which connects various communication devices, including hands-free and voice-controlled options, and the Vocera Care Experience software, designed to improve patient care quality and streamline manual tasks. Additionally, Vocera operates the Experience Innovation Network, collaborating with healthcare organizations to develop innovative solutions that improve patient and care team experiences. The company, founded in 2000 and headquartered in San Jose, California, serves approximately 1,700 healthcare facilities globally, including hospitals and clinics, and distributes its products through direct sales, resellers, and distributors.

Healinx

Series D in 2001
Healinx is a unique medical relationship management application service provider (ASP). Our mission is to increase communication and the satisfaction level between patients and their doctors, while enhancing physician practice efficiency and profitability. By providing a Web-based channel that links patients directly to their personal doctors, Healinx allows patients to communicate with their doctors or access their medical information anytime -- from anywhere. In addition, patients can receive personalized health information from their doctors. The Healinx customized Internet messaging enables doctors and patients to communicate online with state of the art security and privacy. In addition, the Healinx channel includes a set of tools for electronic prescriptions and preventive care.

RelayHealth

Series D in 2001
RelayHealth is a provider of online healthcare communication services that facilitates secure and convenient information exchange among various healthcare stakeholders, including patients, providers, pharmacies, payors, and pharmaceutical manufacturers. The company offers a range of services such as ePrescribing, online refills, access to lab results, reimbursable online visits, and online bill payments. By enabling consistent connectivity among medical companies, doctors, and patients, RelayHealth aims to streamline interactions within the healthcare system. This connectivity ultimately contributes to improved patient care, faster access to necessary services, reduced costs, and enhanced operational efficiency for healthcare providers.

GENBAND

Series D in 2001
GENBAND is a global supplier of IP gateways, session border controllers, and FMC security solutions that enhance the performance and security of fixed and mobile communication networks. The company specializes in developing IP multimedia applications and infrastructure products aimed at transforming the speed and quality of communication. GENBAND's software solutions facilitate seamless connectivity and rapid deployment of services for service providers, enterprises, and systems integrators. By integrating real-time contextual communications into business and consumer applications, GENBAND aims to improve productivity and user engagement across various workflows.
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