Venrock

Surrozen, Inc. is a clinical-stage biopharmaceutical company based in South San Francisco, California, focused on developing targeted regenerative antibodies to enhance tissue and organ repair in response to serious diseases. Founded in 2015, the company specializes in modulating the Wnt pathway, a crucial mediator of tissue regeneration, through its innovative antibody platforms that target specific organs and tissues. Notable programs include SZN-043, designed to stimulate liver regeneration in both acute and chronic liver diseases, and SZN-1326, aimed at repairing damaged epithelial tissue in patients with inflammatory bowel disease. Surrozen's approach extends to multiple organ systems, with potential applications in the intestine, liver, retina, cornea, lung, kidney, cochlea, skin, pancreas, and central nervous system.

Tenaya Therapeutics is a preclinical-stage biotechnology company focused on developing therapies for heart disease and heart failure. It operates three product platforms: cellular regeneration, which aims to regenerate heart tissue by reprogramming cardiac fibroblasts into cardiomyocytes via delivery of proprietary transcription factors; gene therapy, which targets cardiac fibroblasts to deliver therapeutic payloads; and precision medicine, which enables personalized approaches to treat heart disease. Founded in 2016 and headquartered in South San Francisco, California, Tenaya seeks to address the underlying cellular pathologies of diseased myocardium with curative therapies that advance from discovery through development.

ORIC Pharmaceuticals is a clinical-stage biopharmaceutical company dedicated to improving patients' lives by developing therapies that overcome resistance in cancer. Its lead product candidate, ORIC-101, targets the glucocorticoid receptor linked to resistance across various solid tumors. ORIC's second product candidate, ORIC-533, inhibits CD73 to address resistance to chemotherapy and immunotherapy. The company is also developing precision medicines targeting other cancer resistance mechanisms.

Graphite Bio is a clinical-stage gene editing company focused on targeted DNA integration to treat serious diseases. Its platform aims to precisely insert, repair, or replace genetic sequences by integrating therapeutic cargoes at predefined genomic locations, enabling correction of mutations or replacement of disease-causing genes while preserving normal regulatory control. Based in South San Francisco, the company pursues high-efficiency precision gene editing to address underlying causes of disease.

Federation Bio Inc., established in 2018 and headquartered in South San Francisco, California, specializes in the development of microbial therapeutics targeting diseases where the human microbiome holds curative potential. The company's platforms focus on secondary hyperoxaluria and explore treatments for metabolic disorders, immune diseases, and cancer. Federation Bio's approach involves leveraging naturally occurring or engineered bacteria alongside a diverse community of supportive bacteria to drive engraftment and durable therapeutic responses.

Kyruus, Inc. is a Boston-based company that develops web-based software solutions aimed at optimizing physician networks for hospitals, health systems, and life science companies. Founded in 2010, Kyruus offers a suite of analytically driven products designed to enhance provider search and scheduling, ensuring that patients are matched with the most suitable healthcare providers. Key offerings include Kyruus Passport, which allows physicians to track their activity and productivity, and Kyruus Profiles, which enables administrators to analyze physician performance metrics. Additionally, the company provides Kyruus MDSeekyr, a platform for identifying high-value providers, and Kyruus Insight Reports, which help executives evaluate network activity and performance trends. By leveraging a proprietary provider data management platform, Kyruus enhances patient engagement and aligns provider supply with patient demand, ultimately improving the overall healthcare experience. Kyruus also maintains offices in San Francisco and New York.

Concentric Analgesics is a biotechnology company developing non-opioid therapeutics for managing acute and chronic pain, with a focus on single local administration to target pain at the source while limiting systemic exposure. Its products aim to provide effective relief without numbness or weakness during procedures and to simplify ongoing care for patients with osteoarthritis and other conditions. The company is advancing treatments for post-surgical pain, chronic osteoarthritis pain, and refractory pain, including CA-008, an injectable capsaicin prodrug for acute post-surgical pain; CA-051 for epidural administration to treat refractory pain from cancer or amputation; and an injectable therapy for chronic pain associated with osteoarthritis. Founded in 2014, it is based in San Francisco, California.

Kyruus, Inc. is a Boston-based company that develops web-based software solutions aimed at optimizing physician networks for hospitals, health systems, and life science companies. Founded in 2010, Kyruus offers a suite of analytically driven products designed to enhance provider search and scheduling, ensuring that patients are matched with the most suitable healthcare providers. Key offerings include Kyruus Passport, which allows physicians to track their activity and productivity, and Kyruus Profiles, which enables administrators to analyze physician performance metrics. Additionally, the company provides Kyruus MDSeekyr, a platform for identifying high-value providers, and Kyruus Insight Reports, which help executives evaluate network activity and performance trends. By leveraging a proprietary provider data management platform, Kyruus enhances patient engagement and aligns provider supply with patient demand, ultimately improving the overall healthcare experience. Kyruus also maintains offices in San Francisco and New York.

Kyruus, Inc. is a Boston-based company that develops web-based software solutions aimed at optimizing physician networks for hospitals, health systems, and life science companies. Founded in 2010, Kyruus offers a suite of analytically driven products designed to enhance provider search and scheduling, ensuring that patients are matched with the most suitable healthcare providers. Key offerings include Kyruus Passport, which allows physicians to track their activity and productivity, and Kyruus Profiles, which enables administrators to analyze physician performance metrics. Additionally, the company provides Kyruus MDSeekyr, a platform for identifying high-value providers, and Kyruus Insight Reports, which help executives evaluate network activity and performance trends. By leveraging a proprietary provider data management platform, Kyruus enhances patient engagement and aligns provider supply with patient demand, ultimately improving the overall healthcare experience. Kyruus also maintains offices in San Francisco and New York.

CytomX Therapeutics is a clinical-stage oncology-focused biopharmaceutical company that develops proteolytically-activated antibodies based on its Probody technology platform. Probody therapeutics are designed to be activated by the tumor microenvironment, enabling targeted cancer immunotherapies with reduced activity in healthy tissues. The company advances antibody and antibody-drug conjugate programs such as CX-072 (PD-L1), CX-2009 (CD166-targeted PDC), BMS-986249 (CTLA-4 Probody), CX-2029 (CD71-targeted PDC), and BMS-986288 (CTLA-4 Probody) in clinical research, and maintains collaborations with AbbVie, Amgen, Bristol-Myers Squibb, ImmunoGen, Pfizer, and Astellas to develop Probody therapeutics. Founded in 2008 and headquartered in South San Francisco, the company aims to improve the precision and safety of antibody-based therapies for cancer and inflammatory diseases.

Founded in London in 2008, Betable enables game developers to integrate real-money gambling into their mobile and social games legally and securely. It offers platforms for processing transactions, ensuring compliance, and providing player protection services.

Kyruus, Inc. is a Boston-based company that develops web-based software solutions aimed at optimizing physician networks for hospitals, health systems, and life science companies. Founded in 2010, Kyruus offers a suite of analytically driven products designed to enhance provider search and scheduling, ensuring that patients are matched with the most suitable healthcare providers. Key offerings include Kyruus Passport, which allows physicians to track their activity and productivity, and Kyruus Profiles, which enables administrators to analyze physician performance metrics. Additionally, the company provides Kyruus MDSeekyr, a platform for identifying high-value providers, and Kyruus Insight Reports, which help executives evaluate network activity and performance trends. By leveraging a proprietary provider data management platform, Kyruus enhances patient engagement and aligns provider supply with patient demand, ultimately improving the overall healthcare experience. Kyruus also maintains offices in San Francisco and New York.

Kyruus, Inc. is a Boston-based company that develops web-based software solutions aimed at optimizing physician networks for hospitals, health systems, and life science companies. Founded in 2010, Kyruus offers a suite of analytically driven products designed to enhance provider search and scheduling, ensuring that patients are matched with the most suitable healthcare providers. Key offerings include Kyruus Passport, which allows physicians to track their activity and productivity, and Kyruus Profiles, which enables administrators to analyze physician performance metrics. Additionally, the company provides Kyruus MDSeekyr, a platform for identifying high-value providers, and Kyruus Insight Reports, which help executives evaluate network activity and performance trends. By leveraging a proprietary provider data management platform, Kyruus enhances patient engagement and aligns provider supply with patient demand, ultimately improving the overall healthcare experience. Kyruus also maintains offices in San Francisco and New York.

BlogHer is a community and media company that supports women who blog by providing exposure, education, and economic empowerment. It operates a cross-platform media network that publishes and curates news, information, advice, and research on women in social media across topics such as food, fashion, health, work and life, and parenting. The company hosts conferences and runs a publishing network comprising a large group of blogs, offering women creators opportunities to reach audiences, share voices, and develop their businesses. Based in California, BlogHer focuses on connecting women online and in person through content platforms, events, and a network of contributors.

BlogHer is a community and media company that supports women who blog by providing exposure, education, and economic empowerment. It operates a cross-platform media network that publishes and curates news, information, advice, and research on women in social media across topics such as food, fashion, health, work and life, and parenting. The company hosts conferences and runs a publishing network comprising a large group of blogs, offering women creators opportunities to reach audiences, share voices, and develop their businesses. Based in California, BlogHer focuses on connecting women online and in person through content platforms, events, and a network of contributors.

SlideShare, Inc. is an online platform that allows users to upload and share a variety of content, including presentations, infographics, documents, and videos. Founded in 2006 and based in San Francisco, California, the platform serves as a community for professionals, educators, businesses, and non-profit organizations to find and share information on a wide range of topics, including technology, finance, health, and education. Users can engage with the content by rating, commenting, and sharing, fostering collaboration and knowledge exchange. As of August 2020, SlideShare operates as a subsidiary of Scribd, Inc., and continues to enhance its offerings by planning new educational resources in collaboration with partners.

BlogHer is a community and media company that supports women who blog by providing exposure, education, and economic empowerment. It operates a cross-platform media network that publishes and curates news, information, advice, and research on women in social media across topics such as food, fashion, health, work and life, and parenting. The company hosts conferences and runs a publishing network comprising a large group of blogs, offering women creators opportunities to reach audiences, share voices, and develop their businesses. Based in California, BlogHer focuses on connecting women online and in person through content platforms, events, and a network of contributors.

PodTech Network, founded by John Furrier after the success of his podcast InfoTalk, specializes in video podcasting with a focus on technology. The network features five channels and nearly twenty individual shows that explore various topics, including startups, new gadgets, and digital media, often highlighted at music festivals. It showcases interviews with notable figures in the tech industry, such as Robert Scoble and Jason Calacanis, who engage with industry veterans like Ron Conway and emerging startups. PodTech aims to provide insightful content while maintaining an entertaining atmosphere, ensuring that humor and enthusiasm for new technology are integral to its programming. In addition to podcasting, the company develops social media strategies and offers services related to brand engagement, online video shows, and offline events.

PodTech Network, founded by John Furrier after the success of his podcast InfoTalk, specializes in video podcasting with a focus on technology. The network features five channels and nearly twenty individual shows that explore various topics, including startups, new gadgets, and digital media, often highlighted at music festivals. It showcases interviews with notable figures in the tech industry, such as Robert Scoble and Jason Calacanis, who engage with industry veterans like Ron Conway and emerging startups. PodTech aims to provide insightful content while maintaining an entertaining atmosphere, ensuring that humor and enthusiasm for new technology are integral to its programming. In addition to podcasting, the company develops social media strategies and offers services related to brand engagement, online video shows, and offline events.

Simple Star, Inc. develops and distributes software products and services that help consumers to share memories. The company provides PhotoShow, a photo platform that is used to organize and edit digital photos and video clips into multimedia photo shows, including credits, captions, transitions, special effects, and animations with musical soundtracks, as well as allows users to share photo shows on personal computers, televisions, and handheld devices. It also offers various theme packs that turn photo shows into holiday greetings, graduation celebrations, declarations of love, and patriotic celebrations. The company also provides an online service to make and post photo shows on the Web. It provides its products through its partners, including cable companies, digital media software providers, online photo service providers, retailers with photo finishing services, and hardware manufacturers. Simple Star, Inc. was formerly known as Noize Play, Inc. The company was founded in 2001 and is based in San Francisco, California. As of April 24, 2008, Simple Star, Inc. operates as a subsidiary of Sonic Solutions (NasdaqNM:SNIC).

Biospect, Inc. is a South San Francisco-based life sciences technology company focused on developing minimally invasive solutions for identifying and analyzing protein biomarker patterns. These patterns are crucial for differentiating various biological states, which aids in diagnosing and managing diseases, as well as facilitating drug development. The company integrates proprietary technologies in separations, detection, and informatics to create a comprehensive system designed for medical research applications. By advancing the capabilities of biomarker analysis, Biospect aims to enhance the effectiveness of disease management and therapeutic innovation.

Simple Star, Inc. develops and distributes software products and services that help consumers to share memories. The company provides PhotoShow, a photo platform that is used to organize and edit digital photos and video clips into multimedia photo shows, including credits, captions, transitions, special effects, and animations with musical soundtracks, as well as allows users to share photo shows on personal computers, televisions, and handheld devices. It also offers various theme packs that turn photo shows into holiday greetings, graduation celebrations, declarations of love, and patriotic celebrations. The company also provides an online service to make and post photo shows on the Web. It provides its products through its partners, including cable companies, digital media software providers, online photo service providers, retailers with photo finishing services, and hardware manufacturers. Simple Star, Inc. was formerly known as Noize Play, Inc. The company was founded in 2001 and is based in San Francisco, California. As of April 24, 2008, Simple Star, Inc. operates as a subsidiary of Sonic Solutions (NasdaqNM:SNIC).

ORIC Pharmaceuticals is a clinical-stage biopharmaceutical company dedicated to improving patients' lives by developing therapies that overcome resistance in cancer. Its lead product candidate, ORIC-101, targets the glucocorticoid receptor linked to resistance across various solid tumors. ORIC's second product candidate, ORIC-533, inhibits CD73 to address resistance to chemotherapy and immunotherapy. The company is also developing precision medicines targeting other cancer resistance mechanisms.

CytomX Therapeutics is a clinical-stage oncology-focused biopharmaceutical company that develops proteolytically-activated antibodies based on its Probody technology platform. Probody therapeutics are designed to be activated by the tumor microenvironment, enabling targeted cancer immunotherapies with reduced activity in healthy tissues. The company advances antibody and antibody-drug conjugate programs such as CX-072 (PD-L1), CX-2009 (CD166-targeted PDC), BMS-986249 (CTLA-4 Probody), CX-2029 (CD71-targeted PDC), and BMS-986288 (CTLA-4 Probody) in clinical research, and maintains collaborations with AbbVie, Amgen, Bristol-Myers Squibb, ImmunoGen, Pfizer, and Astellas to develop Probody therapeutics. Founded in 2008 and headquartered in South San Francisco, the company aims to improve the precision and safety of antibody-based therapies for cancer and inflammatory diseases.