U.S. Venture Partners

Shoulder Innovations designs and manufactures medical devices for shoulder replacement surgery, focusing on inset glenoid fixation technology to provide a stable glenoid platform and reliable fixation. Its product portfolio includes InSet Total Shoulder Arthroplasty, InSet Reverse Shoulder Arthroplasty, ProVoyance Shoulder Planning Software, and InSet Tray System, along with associated instrumentation. The company distributes its products through partners in the United States and aims to reduce operative time and overall healthcare costs while improving post-surgical implant stability. Founded in 2009, the company is based in Holland, Michigan.

MicroTransponder is a medical device company that develops and commercializes implantable neurostimulation platforms aimed at treating neurological conditions. The company focuses on vagus nerve stimulation to promote neuroplasticity and functional recovery, with products including the Serenity System for tinnitus and Vivistim, an FDA-approved therapy for ischemic stroke survivors with moderate to severe upper-limb impairment more than six months post-stroke. Founded in 2007 and headquartered in Austin, Texas, MicroTransponder's technology combines paired vagus nerve stimulation with wireless delivery of targeted electrical impulses to enhance recovery after neurological injury and disease.

Route 92 Medical, established in 2015 and headquartered in San Mateo, California, specializes in the development of innovative medical devices for stroke treatment. Their flagship product is a stealthy catheter designed for rapid and efficient removal of blood clots during acute ischemic stroke, aiming to improve patient outcomes and enhance recovery. Additionally, the company offers a rapid aspiration thrombectomy system and an intra-cerebral implant delivery system, further expanding their capabilities in stroke care.

Nuvaira, Inc. is a medical device company based in Minneapolis, Minnesota, focused on developing innovative treatments for obstructive lung diseases, particularly chronic obstructive pulmonary disease (COPD). Founded in 2008, Nuvaira specializes in a novel catheter-based Lung Denervation System that aims to address airway nerve hyperactivity by targeting the parasympathetic innervation of the lungs. This minimally invasive procedure is designed to improve lung function, enhance exercise capacity, and elevate the quality of life for patients suffering from chronic respiratory conditions. With a commitment to advancing treatment options, Nuvaira seeks to reduce the clinical consequences associated with neural hyperactivity in conditions such as COPD and asthma.

HotelTonight, Inc. is a mobile application designed for booking same-day hotel accommodations, specializing in last-minute deals for unsold rooms. Founded in 2010 and headquartered in San Francisco, California, the platform provides a marketplace that allows hotels to fill last-minute vacancies that would otherwise remain unoccupied. Users can easily access these discounted rates through their smartphones and tablets, making it a convenient option for business travelers, leisure travelers, and locals alike. The application enables bookings for rooms up to 100 days in advance, catering to various travel needs while ensuring significant savings for its customers. As of April 2019, HotelTonight operates as a subsidiary of Airbnb, Inc.

Zefr is a video advertising company that specializes in creating targeted video ad placements through its proprietary technology and content rights management platform. The company focuses on aligning the right advertisements with appropriate content on popular platforms, ensuring that brands can safely and effectively scale their video marketing campaigns. By combining advanced technology with human review, Zefr offers customized packages that enhance the precision and impact of video advertising. The company's name pays homage to the Zephyr skate team of the 1970s, reflecting a spirit of innovation and boundary-pushing that is central to its mission.

Zerto is a company that specializes in providing enterprise-class disaster recovery and business continuity software solutions. Founded in 2009 and headquartered in Boston, Massachusetts with additional offices globally, Zerto focuses on keeping IT infrastructure running continuously for both enterprises and cloud environments. Its flagship product, Zerto Virtual Replication, enables the protection, recovery, and migration of applications across various cloud and virtualized data centers. The company's BC/DR Platform offers disaster recovery as a service for public, private, and hybrid clouds, catering to industries such as healthcare, legal, and financial services.

Inspire Medical Systems, Inc. is a medical technology company dedicated to developing and commercializing minimally invasive solutions for patients suffering from obstructive sleep apnea (OSA). Founded in 2007 and headquartered in Golden Valley, Minnesota, the company specializes in innovative implantable neurostimulation technologies. Its primary product, the Inspire system, utilizes a proprietary Upper Airway Stimulation (UAS) therapy that provides a safe and effective treatment for moderate to severe OSA. This technology leverages established principles from cardiac pacing and neurostimulation to deliver mild hypoglossal nerve stimulation, which helps maintain an open airway by continuously monitoring the patient's breathing. Inspire Medical Systems operates primarily in the United States and Europe, generating most of its revenue from the U.S. market.

Electric Cloud, Inc. is a software company that specializes in release automation and continuous delivery solutions for organizations globally. Founded in 2002 and based in San Jose, California, the company offers products such as ElectricFlow, an adaptive release orchestration platform that facilitates control over releases at any scale, and Electric Accelerator, which optimizes build and test processes by distributing workloads across various resources. Electric Cloud serves a diverse range of industries, including financial services, automotive, and Internet of Things, helping clients like Cisco, Intel, and Lockheed Martin enhance their DevOps productivity. By automating and streamlining the software delivery process, Electric Cloud enables organizations to reduce costs and risks associated with software releases, ultimately improving time-to-market, developer productivity, and software quality. As of April 2019, Electric Cloud operates as a subsidiary of CloudBees, Inc.

ThreatMetrix Inc. is a provider of context-based business security and fraud prevention solutions, serving various industries globally, including e-commerce, healthcare, and financial services. Founded in 2005 and based in San Jose, California, the company offers the TrustDefender Cybercrime Protection Platform, which conducts real-time assessments of users and devices to identify potential fraudsters and hackers. Its services include context-based authentication for secure access to enterprise applications, protection against account takeovers, payment fraud, and web-based fraud. Additionally, ThreatMetrix provides tailored security solutions, fraud prevention analysis, and forensic services. With insights drawn from 1.4 billion anonymized user identities, the company supports over 100 million daily authentication and trust decisions, helping businesses enhance security while facilitating a seamless digital experience for legitimate customers. As of 2018, ThreatMetrix operates as a subsidiary of LexisNexis Risk Solutions Inc.

Electric Cloud, Inc. is a software company that specializes in release automation and continuous delivery solutions for organizations globally. Founded in 2002 and based in San Jose, California, the company offers products such as ElectricFlow, an adaptive release orchestration platform that facilitates control over releases at any scale, and Electric Accelerator, which optimizes build and test processes by distributing workloads across various resources. Electric Cloud serves a diverse range of industries, including financial services, automotive, and Internet of Things, helping clients like Cisco, Intel, and Lockheed Martin enhance their DevOps productivity. By automating and streamlining the software delivery process, Electric Cloud enables organizations to reduce costs and risks associated with software releases, ultimately improving time-to-market, developer productivity, and software quality. As of April 2019, Electric Cloud operates as a subsidiary of CloudBees, Inc.

Box is a cloud content management and file sharing service that offers secure storage and collaboration tools for users and enterprises. Founded in 2005, the company launched its platform in 2006 with the aim of facilitating access to and sharing of content across various devices and networks. Box serves over 8 million users, providing features that allow individuals and organizations to securely manage their critical information in the cloud. The platform supports a wide range of content formats and includes tools for governance and e-signature, enhancing workflow management and collaboration. Headquartered in Redwood City, California, Box continues to evolve its offerings to meet the needs of businesses across various industries.

Xirrus, Inc., established in 2004 and headquartered in Thousand Oaks, California, specializes in wireless access network solutions. It offers a range of products including high-density and outdoor access points, wired switches, network accessories like enclosures and mountings, and power options. Xirrus also provides software solutions such as the Xirrus Management System for network deployment and management, EasyPass Personal Wi-Fi for secure public Wi-Fi access, Wi-Fi Designer for predictive heat-map network design, and XA4 for high-density user experiences in large venues. Serving clients across enterprise, education, healthcare, hospitality, and other markets both domestically and internationally, Xirrus operates as a subsidiary of Riverbed Technology, Inc., focusing on delivering robust wireless networking solutions.

Yammer, established in 2008, is a business specializing in enterprise social networking. It facilitates real-time collaboration among employees across different departments, locations, and applications. Key features include creating groups for project collaboration, sharing and editing documents, and accessing the platform via web, desktop, and mobile devices. Yammer can also integrate with other systems like Microsoft SharePoint. With over 7 million users, including 85% of Fortune 500 companies, Yammer was acquired by Microsoft in 2012.

CardioKinetix develops transcatheter implants for treating heart failure. Its flagship product is Parachute, a ventricular partitioning device designed to improve overall cardiac function in patients who have experienced a heart attack. The company serves customers primarily in the United States and Europe.

Solyndra is a manufacturer of cylindrical panels utilizing CIGS thin-film solar cell technology, located in Fremont, California. Established in 2005, the company focuses on designing and producing photovoltaic systems that include both panels and mounting hardware specifically for the commercial rooftop market. Solyndra employs high-volume manufacturing techniques to address the needs of the global solar industry. Its proprietary cylindrical modules are engineered to achieve low installation costs while maximizing solar energy output, particularly on low-slope commercial rooftops. The company operates a fully-automated manufacturing facility spanning 300,000 square feet, underscoring its commitment to efficiency and innovation in solar technology.

Sanarus Medical, Inc. specializes in developing and marketing minimally invasive devices for the diagnosis and treatment of breast tumors. The company offers the Visica Treatment System, which utilizes cryoablation to treat breast fibroadenomas, and the Cassi II rotational core biopsy system, an automated device designed for obtaining contiguous biopsy samples. Additionally, Sanarus provides the ImarC tissue marker system, which includes breast tissue markers visible under various imaging modalities. Founded in 1999 and headquartered in Pleasanton, California, Sanarus Medical focuses on providing innovative solutions for both cancerous and non-cancerous breast conditions.

CipherMax, Inc. provides enterprise-class storage security solutions for securing information assets and achieving compliance with government regulations. The company offers CipherMax CM140T, a storage security system for tapes that provides line-speed encryption processing and centralized security administration solutions for legacy and LTO-4 drives. It also provides CipherMax CM180D, a compact storage security system to integrate high performance encryption with SAN access control and 16-ports connectivity for fabric-based protection of sensitive data on disks; CipherMax CM250, an enterprise storage security system to integrate into existing SANs with 64-ports connectivity; and CipherMax CM500, a system for securing disk-based stored data for enterprise data centers with high port count storage environments. In addition, it offers SANCruiser, a secure storage management software for the management of systems, SAN, and security functions in an enterprise storage environment; and KeyCruiser, a key lifecycle management system for the secure administration of data encryption keys. CipherMax, Inc. was formerly known as MaXXan Systems, Inc. and changed its name to CipherMax, Inc. in 2007. The company was founded in 2000 and is based in San Jose, California.

Force10 Networks, Inc. is a manufacturer of networking equipment and solutions that cater to data center and network deployment needs. The company operates primarily in two segments: Ethernet and Transport. The Ethernet segment includes 1 GbE and 10GbE switches and routers designed for data centers, enterprises, and service providers, while the Transport segment offers products for metro and inter-office optical networks, wireless aggregation, and converged business access networks. Force10 is recognized for its high-performance data center solutions, which are built on open, standards-based hardware and software, enabling clients to achieve scalability, reliability, and application awareness. The company's products are marketed through a direct sales force in the United States and through various international channel partners. Founded in 1999 and based in San Jose, California, Force10 Networks operates as a subsidiary of Dell Marketing L.P.

BeVocal, Inc. is a provider of hosted customer automated self-service solutions, primarily serving communications service providers and enterprise call centers. Founded in 1999 and headquartered in Mountain View, California, the company specializes in developing speech-based customer care solutions tailored for the mobile communications market. BeVocal offers an integrated suite of voice and data applications, including speech-enabled call routing and destination applications that facilitate automated service interactions. Its self-service systems empower users to navigate customer service processes independently, thereby reducing the need for live agents. The solutions provided by BeVocal enhance customer satisfaction and drive revenue growth by enabling efficient customer service activation, care, and fulfillment. In 2007, BeVocal became a subsidiary of Nuance Communications, Inc.

Agility Communications, Inc. provides laser solutions for the optical network. The company focuses on offering tunable transponder and tunable laser solutions for carriers and system providers. It offers tunable transmitter and transponder products. The company was founded in 1998 and is based in Santa Barbara, California. As of November 30, 2005, Agility Communications, Inc. operates as a subsidiary of JDS Uniphase Corp.

ON24 is a cloud-based engagement platform that specializes in webinar-based marketing, virtual events, and demand generation. The platform combines interactive webcasts with personalized content, analytics, and benchmarking to help marketers attract leads, qualify opportunities, and accelerate the sales cycle. It enables marketers to create, reuse, and distribute video and webinar content, deliver engaging virtual events, and integrate with leading CRM and marketing automation systems for seamless data flow. ON24 also offers services for virtual conferences, corporate communications, and talent development, including virtual training and onboarding, with capabilities for audience engagement and real-time measurement. The company serves multiple industries worldwide, including life sciences, legal, financial services, technology, manufacturing, and professional services. Founded in 1998 and headquartered in San Francisco, ON24 maintains additional offices across North America, Europe, and Asia.

RelayHealth is a provider of online healthcare communication services that facilitates secure and convenient information exchange among various healthcare stakeholders, including patients, providers, pharmacies, payors, and pharmaceutical manufacturers. The company offers a range of services such as ePrescribing, online refills, access to lab results, reimbursable online visits, and online bill payments. By enabling consistent connectivity among medical companies, doctors, and patients, RelayHealth aims to streamline interactions within the healthcare system. This connectivity ultimately contributes to improved patient care, faster access to necessary services, reduced costs, and enhanced operational efficiency for healthcare providers.