SV Health Investors

Founded in 2018, Perfuze is a medical device company based in Galway, Ireland. It specializes in developing catheter-based aspiration technology designed to treat acute ischemic stroke efficiently and effectively.

SpectraWAVE is a medical device company that develops intravascular optical imaging systems to diagnose and treat cardiovascular disease. Its technology integrates imaging and computation to help interventional cardiologists identify vulnerable plaques and guide coronary interventions, improving outcomes for patients with coronary artery disease. Headquartered in Waltham, Massachusetts, the company was founded in 2017.

CSA Medical, Inc., established in 1993 and headquartered in Baltimore, Maryland, specializes in the development and manufacturing of spray cryotherapy medical devices. Its primary product, truFreeze, utilizes cold liquid nitrogen to destroy unwanted tissue across dermatology, gynecology, and general surgery fields while promoting healthy tissue regrowth. CSA Medical also offers the Rapid AV Spray Kit to enhance truFreeze's efficiency. The company operates a research and development facility in Lexington, Massachusetts.

Spineology Inc. is a medical device company specializing in anatomy-conserving technology solutions for spine surgery. Founded in 1996 and headquartered in Saint Paul, Minnesota, the company offers a range of products designed to enhance surgical efficiency and improve patient outcomes. Its product lineup includes pedicular fixation systems like Threshold and Fortress, interbody fusion solutions such as Duo and Rampart, and biologics like the Prime liquid tissue matrix and Armor amniotic wound covering. Additionally, Spineology provides a variety of surgical instruments, including the Capture facet fixation system, VIA spinous process fixation system, and Medius midline retractor system, among others. The company focuses on using minimally invasive techniques to reduce post-operative pain and facilitate quicker recovery for patients suffering from spinal-related issues.

Miach Orthopaedics is a medical device company based in Westborough, Massachusetts, specializing in the development of bio-engineered surgical implants aimed at promoting new tissue growth and aiding in connective tissue repair. Founded in 2016, the company focuses on its innovative Bridge-Enhanced ACL Repair technology, which serves as an alternative to traditional anterior cruciate ligament (ACL) reconstruction. This technology provides surgeons with a method to restore the normal anatomy and function of the knee for patients who have experienced ACL injuries, offering a promising option for recovery and rehabilitation.

Robling Medical is a specialized manufacturer serving the healthcare industry. It offers contract manufacturing services tailored for medical organizations, focusing on product design and development through to assembly process design, manufacturing, packaging, sterilization, and distribution of medical products. The company aims to facilitate clients' engineering needs and ensure regulatory compliance, supporting them in bringing their medical devices to market efficiently.

PayMedix began as the healthcare payment platform for Health Payment Systems (HPS) in 2008. HPS, headquartered in Milwaukee, Wisconsin, is a privately held healthcare technology and services organization with an independent network of 96 hospital facilities and 22,600 individual providers. PayMedix has processed more than $5 billion in medical payments for hospital systems and physician practices and can be implemented with any PPO or HMO network.

Founded in 2018, Perfuze is a medical device company based in Galway, Ireland. It specializes in developing catheter-based aspiration technology designed to treat acute ischemic stroke efficiently and effectively.

PayMedix began as the healthcare payment platform for Health Payment Systems (HPS) in 2008. HPS, headquartered in Milwaukee, Wisconsin, is a privately held healthcare technology and services organization with an independent network of 96 hospital facilities and 22,600 individual providers. PayMedix has processed more than $5 billion in medical payments for hospital systems and physician practices and can be implemented with any PPO or HMO network.

Leiters Health is an FDA-registered 503B outsourcing provider specializing in high-quality compounded sterile preparations for ophthalmology and hospital-based services. With nearly a century of experience, the company is dedicated to delivering essential medications to healthcare professionals and their patients. Leiters Health offers a comprehensive portfolio that includes ready-to-administer products such as pre-filled syringes, vials, bags, and injectable compounds, as well as opioid-free surgical pain services and specialized cardioplegic and ophthalmic products. The company's team of experts in sterile pharmaceutical manufacturing and compounding employs robust processes and advanced manufacturing facilities to ensure the highest standards of quality and consistency in their offerings, prioritizing patient safety and trust.

Evidation Health, Inc. is a California-based company that specializes in developing digital tools and technologies for healthcare data analytics. Founded in 2012, the company connects digital health firms with healthcare providers, payers, and other stakeholders through its advanced technology solutions. Its primary offerings include a data platform that transforms everyday behavior data from various sources, such as sensors and devices, into meaningful health insights, and a technology-enabled service called Studies that facilitates real-world research using this data. Evidation Health aims to enhance the understanding of how daily behaviors impact health and disease, ultimately empowering individuals to engage in better health outcomes. The company's commitment to user privacy and control over health data has garnered trust from millions of individuals, enabling them to participate in innovative health programs and research.

EBT Medical, Inc. is a clinical-stage company based in Boston, Massachusetts, with an additional office in Toronto, Canada. Founded in 2014, the company specializes in developing innovative, non-invasive neuromodulation therapies aimed at treating pelvic health disorders, particularly focusing on patients with overactive bladder. EBT Medical's technology is centered on the Saphenous nerve and is designed to provide discreet treatment options that enable patients to restore pelvic health function without the side effects typically associated with conventional therapies. The company emerged from scientific discoveries made at the University of Toronto and has benefited from a startup incubation program that has fostered numerous successful ventures in the past decade.

AeroCare Holdings, Inc., established in 2002 and headquartered in Orlando, Florida, specializes in distributing home medical equipment in the United States. The company offers a range of respiratory products, including oxygen, CPAP/BiPAP machines and supplies, nebulizers, and oxygen concentrator instructions, catering to patients with breathing difficulties such as COPD, CHF, and OSA. Additionally, AeroCare provides mobility aids like wheelchairs, walkers, and canes, along with other daily living and medical supplies. The company sells its products through customer service representatives and offers direct purchasing options for CPAP and respiratory equipment, recognizing insurance limitations.

Founded in 2013, Bardy Diagnostics specializes in developing advanced cardiac monitoring devices. Its flagship product is the Carnation Ambulatory Monitor (CAM), a discreet and comfortable patch monitor designed to capture clear P-wave signals for accurate arrhythmia detection. The company also offers BDxCONNECT, a patient management system that aids clinical decision-making by providing easy access to CAM reports.

CSA Medical, Inc., established in 1993 and headquartered in Baltimore, Maryland, specializes in the development and manufacturing of spray cryotherapy medical devices. Its primary product, truFreeze, utilizes cold liquid nitrogen to destroy unwanted tissue across dermatology, gynecology, and general surgery fields while promoting healthy tissue regrowth. CSA Medical also offers the Rapid AV Spray Kit to enhance truFreeze's efficiency. The company operates a research and development facility in Lexington, Massachusetts.

Evidation Health, Inc. is a California-based company that specializes in developing digital tools and technologies for healthcare data analytics. Founded in 2012, the company connects digital health firms with healthcare providers, payers, and other stakeholders through its advanced technology solutions. Its primary offerings include a data platform that transforms everyday behavior data from various sources, such as sensors and devices, into meaningful health insights, and a technology-enabled service called Studies that facilitates real-world research using this data. Evidation Health aims to enhance the understanding of how daily behaviors impact health and disease, ultimately empowering individuals to engage in better health outcomes. The company's commitment to user privacy and control over health data has garnered trust from millions of individuals, enabling them to participate in innovative health programs and research.

Stimwave Technologies, Inc., established in 2010, is a medical device company based in Scottsdale, Arizona. It specializes in the development, manufacturing, and marketing of wireless, microsize injectable medical devices for neurology markets. The company's flagship product, the Freedom SCS System, is a spinal cord stimulator used to alleviate chronic low back and leg pain. Additionally, Stimwave offers the StimQ PNS System, a peripheral nerve stimulator that targets specific nerves to treat chronic pain. Both products utilize the company's proprietary MicroStim wireless technology. Stimwave operates under the name Stimwave Technologies, Inc., following a rebrand from its former name, Neural Micro Incorporated.

Avrobio is a clinical-stage biotechnology company focused on developing ex vivo lentiviral-based gene therapies to treat rare diseases with a single dose. Its pipeline includes AVR-RD-01 for Fabry disease, AVR-RD-02 for type 1 Gaucher disease, and AVR-RD-03 for Pompe disease.

Misonix is a leading medical device company specializing in ultrasonic surgical technology. The company designs, manufactures, and markets innovative devices that enhance clinical outcomes in various surgical fields, including neurosurgery, orthopedic surgery, plastic surgery, and wound care. Misonix's product portfolio features advanced ultrasonic platforms such as aspirators for soft and hard tissue removal, instruments for laparoscopic procedures, and devices for wound cleansing and debridement. Additionally, its offerings include tools for precision bone cutting and sculpting, as well as liposuction instruments aimed at improving body aesthetics. Notable products include BoneScalpel, NeXus, Sequel, SonaStar, SonicOne, Theragenesis, TheraSkin, and Therion. Misonix serves a global market, with a presence in regions such as the United States and the United Kingdom, contributing to the overall value of the healthcare system.

Founded in 2013, Bardy Diagnostics specializes in developing advanced cardiac monitoring devices. Its flagship product is the Carnation Ambulatory Monitor (CAM), a discreet and comfortable patch monitor designed to capture clear P-wave signals for accurate arrhythmia detection. The company also offers BDxCONNECT, a patient management system that aids clinical decision-making by providing easy access to CAM reports.

Good Start Genetics, Inc. is a molecular diagnostics company based in Cambridge, Massachusetts, founded in 2007. It specializes in genetic screening for inherited diseases, aiming to transform reproductive medicine by providing actionable information to physicians and patients. The company offers a range of services, including EmbryVu, a preimplantation genetic screening test designed to enhance in vitro fertilization outcomes by identifying suitable embryos for implantation. Additionally, Good Start Genetics provides a comprehensive array of genetic carrier screening tests through its GoodStart Select program, utilizing advanced next-generation DNA sequencing technology along with other established genetic screening methods. This focus on high carrier detection rates and commitment to customer care and genetic counseling positions the company as a leader in the field of pre-pregnancy genetic testing and diagnostics. As of August 2017, Good Start Genetics operates as a subsidiary of Invitae Corporation.

CardioKinetix develops transcatheter implants for treating heart failure. Its flagship product is Parachute, a ventricular partitioning device designed to improve overall cardiac function in patients who have experienced a heart attack. The company serves customers primarily in the United States and Europe.

CSA Medical, Inc., established in 1993 and headquartered in Baltimore, Maryland, specializes in the development and manufacturing of spray cryotherapy medical devices. Its primary product, truFreeze, utilizes cold liquid nitrogen to destroy unwanted tissue across dermatology, gynecology, and general surgery fields while promoting healthy tissue regrowth. CSA Medical also offers the Rapid AV Spray Kit to enhance truFreeze's efficiency. The company operates a research and development facility in Lexington, Massachusetts.

Cibiem Inc. is a medical device manufacturer specializing in Carotid Body Modulation (CBM), which targets sympathetic nervous system-mediated diseases such as hypertension, heart failure, diabetes, and renal failure. Founded in 2010 and based in Los Altos, California, with an additional office in Teaneck, New Jersey, Cibiem utilizes a proprietary, minimally invasive, catheter-based approach to deliver its treatments. The company was co-founded by Mark Gelfand and Howard R. Levin, M.D., who bring a wealth of experience in medical innovation and entrepreneurship. Cibiem aims to enhance the efficacy of medical interventions for serious health conditions, thereby improving patient outcomes in the treatment of these critical disorders.

ValenTx, Inc. is a medical device company based in Maple Grove, Minnesota, that specializes in developing innovative therapy solutions for patients suffering from obesity and obesity-related metabolic disorders. Founded in 2002, ValenTx focuses on minimally-invasive treatment methods, including an endoluminal bypass therapy that replicates the anatomical changes of the traditional Roux-en-Y gastric bypass procedure. This technology features an adjustable, removable, and replaceable device designed to address conditions such as type-2 diabetes and hypertension, aiming to improve patient outcomes in the management of these chronic health issues.

CardioFocus develops endoscopic ablation systems for atrial fibrillation, including the HeartLight Endoscopic Ablation System with direct visualization and energy-delivery capabilities for pulmonary vein isolation, as well as the HeartLight Excalibur Balloon and HeartLight X3 System for stable tissue contact and controlled lesion creation across varying pulmonary vein anatomies. The company integrates a balloon catheter, endoscope, deflectable sheath, and console to enable electrophysiologists to tailor ablations to patient needs. Founded in 1990 and based in Marlborough, Massachusetts, CardioFocus aims to advance treatment of cardiac arrhythmias through visualization-guided devices.

AcuFocus, Inc. is an ophthalmic medical device company based in Irvine, California, specializing in small aperture technologies aimed at improving near vision. Founded in 2001, the company develops and markets innovative solutions for presbyopia, including the KAMRA inlay, which helps patients restore their near vision without compromising distance vision. Additionally, AcuFocus offers the IC-8 IOL, a small aperture lens designed for cataract patients, providing a broad range of vision from near to far distances. The company also produces the AcuTarget HD, a diagnostic and surgical planning instrument that assists in the optimal treatment selection for various eye conditions such as LASIK, cataracts, and dry eye. AcuFocus distributes its products through partners across the Americas, Asia-Pacific, Europe, and the Middle East, serving both physicians and patients in the vision care market.

Avrobio is a clinical-stage biotechnology company focused on developing ex vivo lentiviral-based gene therapies to treat rare diseases with a single dose. Its pipeline includes AVR-RD-01 for Fabry disease, AVR-RD-02 for type 1 Gaucher disease, and AVR-RD-03 for Pompe disease.

Good Start Genetics, Inc. is a molecular diagnostics company based in Cambridge, Massachusetts, founded in 2007. It specializes in genetic screening for inherited diseases, aiming to transform reproductive medicine by providing actionable information to physicians and patients. The company offers a range of services, including EmbryVu, a preimplantation genetic screening test designed to enhance in vitro fertilization outcomes by identifying suitable embryos for implantation. Additionally, Good Start Genetics provides a comprehensive array of genetic carrier screening tests through its GoodStart Select program, utilizing advanced next-generation DNA sequencing technology along with other established genetic screening methods. This focus on high carrier detection rates and commitment to customer care and genetic counseling positions the company as a leader in the field of pre-pregnancy genetic testing and diagnostics. As of August 2017, Good Start Genetics operates as a subsidiary of Invitae Corporation.

Founded in 2005, Halscion specializes in developing biocompatible hydrogel scaffolds designed to improve wound healing and reduce scarring. These single-use devices are applied during surgeries at the dermal-subdermal interface of wounds by injection, allowing the patient's own cells to organize and propagate into the wound.

Direct Flow Medical is a medical device company specializing in the development of innovative transcatheter aortic valve replacement systems aimed at treating heart valve diseases. The company's primary focus is on creating a percutaneous aortic tissue valve prosthesis, which offers patients suffering from cardiac valve insufficiency a safe and effective treatment option. With approximately 1.2 million individuals over the age of 65 affected by calcified aortic valves, and only about 150,000 receiving surgical intervention annually, Direct Flow Medical addresses a significant gap in patient care. Their technology allows heart surgeons to conduct repeated assessments of hemodynamic performance prior to final implantation, thereby enhancing patient outcomes and minimizing complications associated with invasive surgeries.

CardioFocus develops endoscopic ablation systems for atrial fibrillation, including the HeartLight Endoscopic Ablation System with direct visualization and energy-delivery capabilities for pulmonary vein isolation, as well as the HeartLight Excalibur Balloon and HeartLight X3 System for stable tissue contact and controlled lesion creation across varying pulmonary vein anatomies. The company integrates a balloon catheter, endoscope, deflectable sheath, and console to enable electrophysiologists to tailor ablations to patient needs. Founded in 1990 and based in Marlborough, Massachusetts, CardioFocus aims to advance treatment of cardiac arrhythmias through visualization-guided devices.

AcuFocus, Inc. is an ophthalmic medical device company based in Irvine, California, specializing in small aperture technologies aimed at improving near vision. Founded in 2001, the company develops and markets innovative solutions for presbyopia, including the KAMRA inlay, which helps patients restore their near vision without compromising distance vision. Additionally, AcuFocus offers the IC-8 IOL, a small aperture lens designed for cataract patients, providing a broad range of vision from near to far distances. The company also produces the AcuTarget HD, a diagnostic and surgical planning instrument that assists in the optimal treatment selection for various eye conditions such as LASIK, cataracts, and dry eye. AcuFocus distributes its products through partners across the Americas, Asia-Pacific, Europe, and the Middle East, serving both physicians and patients in the vision care market.

AeroCare Holdings, Inc., established in 2002 and headquartered in Orlando, Florida, specializes in distributing home medical equipment in the United States. The company offers a range of respiratory products, including oxygen, CPAP/BiPAP machines and supplies, nebulizers, and oxygen concentrator instructions, catering to patients with breathing difficulties such as COPD, CHF, and OSA. Additionally, AeroCare provides mobility aids like wheelchairs, walkers, and canes, along with other daily living and medical supplies. The company sells its products through customer service representatives and offers direct purchasing options for CPAP and respiratory equipment, recognizing insurance limitations.

Good Start Genetics, Inc. is a molecular diagnostics company based in Cambridge, Massachusetts, founded in 2007. It specializes in genetic screening for inherited diseases, aiming to transform reproductive medicine by providing actionable information to physicians and patients. The company offers a range of services, including EmbryVu, a preimplantation genetic screening test designed to enhance in vitro fertilization outcomes by identifying suitable embryos for implantation. Additionally, Good Start Genetics provides a comprehensive array of genetic carrier screening tests through its GoodStart Select program, utilizing advanced next-generation DNA sequencing technology along with other established genetic screening methods. This focus on high carrier detection rates and commitment to customer care and genetic counseling positions the company as a leader in the field of pre-pregnancy genetic testing and diagnostics. As of August 2017, Good Start Genetics operates as a subsidiary of Invitae Corporation.

Soffio Medical, Inc. is a Boston-based company focused on developing innovative medical devices for respiratory diseases. The firm specializes in implantable technologies that aim to address chronic obstructive pulmonary disease (COPD) and similar conditions. Its devices are designed to implement an airway bypass concept, allowing for the venting of trapped air from areas distal to high-resistance airways. This approach helps reduce residual lung volume and alleviates symptoms associated with respiratory diseases, ultimately enhancing the quality of life for patients.

AcuFocus, Inc. is an ophthalmic medical device company based in Irvine, California, specializing in small aperture technologies aimed at improving near vision. Founded in 2001, the company develops and markets innovative solutions for presbyopia, including the KAMRA inlay, which helps patients restore their near vision without compromising distance vision. Additionally, AcuFocus offers the IC-8 IOL, a small aperture lens designed for cataract patients, providing a broad range of vision from near to far distances. The company also produces the AcuTarget HD, a diagnostic and surgical planning instrument that assists in the optimal treatment selection for various eye conditions such as LASIK, cataracts, and dry eye. AcuFocus distributes its products through partners across the Americas, Asia-Pacific, Europe, and the Middle East, serving both physicians and patients in the vision care market.

Cibiem Inc. is a medical device manufacturer specializing in Carotid Body Modulation (CBM), which targets sympathetic nervous system-mediated diseases such as hypertension, heart failure, diabetes, and renal failure. Founded in 2010 and based in Los Altos, California, with an additional office in Teaneck, New Jersey, Cibiem utilizes a proprietary, minimally invasive, catheter-based approach to deliver its treatments. The company was co-founded by Mark Gelfand and Howard R. Levin, M.D., who bring a wealth of experience in medical innovation and entrepreneurship. Cibiem aims to enhance the efficacy of medical interventions for serious health conditions, thereby improving patient outcomes in the treatment of these critical disorders.

AcuFocus, Inc. is an ophthalmic medical device company based in Irvine, California, specializing in small aperture technologies aimed at improving near vision. Founded in 2001, the company develops and markets innovative solutions for presbyopia, including the KAMRA inlay, which helps patients restore their near vision without compromising distance vision. Additionally, AcuFocus offers the IC-8 IOL, a small aperture lens designed for cataract patients, providing a broad range of vision from near to far distances. The company also produces the AcuTarget HD, a diagnostic and surgical planning instrument that assists in the optimal treatment selection for various eye conditions such as LASIK, cataracts, and dry eye. AcuFocus distributes its products through partners across the Americas, Asia-Pacific, Europe, and the Middle East, serving both physicians and patients in the vision care market.

ReShape Lifesciences is a medical device company focused on technologies to treat obesity and metabolic diseases. The company develops and commercializes products designed to provide less invasive options for weight loss, including the Lap-Band System, an adjustable gastric banding device for long-term obesity management. It also has the ReShape Vest system, an investigational laparoscopically implanted device that wraps around the stomach and is designed to support weight loss without permanent changes to the GI tract; the Vest is primarily marketed outside the United States. The company traces its origins to EnteroMedics and adopted the ReShape Lifesciences name in 2017. It is headquartered in San Clemente, California, and operates in multiple international markets.

EBR Systems is a medical device company that develops implantable wireless tissue stimulation systems for cardiac rhythm management. It focuses on therapies for heart failure and cardiac arrhythmias, including a wireless left ventricular endocardial pacing system used to deliver pacing stimulation directly inside the left ventricle as part of cardiac resynchronization therapy. Founded in 2003 and headquartered in Sunnyvale, California, EBR Systems pursues novel approaches in the field and operates primarily in the United States.

CardioKinetix develops transcatheter implants for treating heart failure. Its flagship product is Parachute, a ventricular partitioning device designed to improve overall cardiac function in patients who have experienced a heart attack. The company serves customers primarily in the United States and Europe.

Direct Flow Medical is a medical device company specializing in the development of innovative transcatheter aortic valve replacement systems aimed at treating heart valve diseases. The company's primary focus is on creating a percutaneous aortic tissue valve prosthesis, which offers patients suffering from cardiac valve insufficiency a safe and effective treatment option. With approximately 1.2 million individuals over the age of 65 affected by calcified aortic valves, and only about 150,000 receiving surgical intervention annually, Direct Flow Medical addresses a significant gap in patient care. Their technology allows heart surgeons to conduct repeated assessments of hemodynamic performance prior to final implantation, thereby enhancing patient outcomes and minimizing complications associated with invasive surgeries.

Ximedica has been a prominent player in the medical device industry for over 30 years, offering comprehensive research, development, regulatory, and manufacturing services. The company specializes in device and systems design, employing a human-centered, vertically integrated approach to enhance product efficiency from conception to market delivery. Ximedica's experienced, cross-disciplinary teams address complex development challenges, enabling clients to explore new market opportunities and achieve award-winning designs while exceeding sales targets. The firm emphasizes quality and regulatory assurance, underscored by its ISO 13485:2003 certification, which reflects its commitment to maintaining high standards in medical device innovation.

AcuFocus, Inc. is an ophthalmic medical device company based in Irvine, California, specializing in small aperture technologies aimed at improving near vision. Founded in 2001, the company develops and markets innovative solutions for presbyopia, including the KAMRA inlay, which helps patients restore their near vision without compromising distance vision. Additionally, AcuFocus offers the IC-8 IOL, a small aperture lens designed for cataract patients, providing a broad range of vision from near to far distances. The company also produces the AcuTarget HD, a diagnostic and surgical planning instrument that assists in the optimal treatment selection for various eye conditions such as LASIK, cataracts, and dry eye. AcuFocus distributes its products through partners across the Americas, Asia-Pacific, Europe, and the Middle East, serving both physicians and patients in the vision care market.

Spinal Kinetics LLC is a medical device company based in Sunnyvale, California, founded in 2003. The company specializes in the design and development of non-fusion motion preservation systems for treating degenerative diseases of the cervical and lumbar spine. Its flagship products, the M6-C and M6-L artificial discs, offer innovative options for artificial cervical and lumbar disc replacements, respectively. These discs are uniquely engineered to replicate the anatomical and biomechanical properties of natural intervertebral discs by incorporating an artificial nucleus and annulus. Spinal Kinetics collaborates with spine surgeons to enhance the effectiveness of its devices, which are distributed in various countries, including Australia, Germany, Spain, and the United Kingdom. The company operates as a subsidiary of Orthofix Medical Inc.

CardioFocus develops endoscopic ablation systems for atrial fibrillation, including the HeartLight Endoscopic Ablation System with direct visualization and energy-delivery capabilities for pulmonary vein isolation, as well as the HeartLight Excalibur Balloon and HeartLight X3 System for stable tissue contact and controlled lesion creation across varying pulmonary vein anatomies. The company integrates a balloon catheter, endoscope, deflectable sheath, and console to enable electrophysiologists to tailor ablations to patient needs. Founded in 1990 and based in Marlborough, Massachusetts, CardioFocus aims to advance treatment of cardiac arrhythmias through visualization-guided devices.

Founded in 2005, AqueSys specializes in developing and commercializing innovative ophthalmic devices. Its flagship product is the XEN gel stent, an implantable device designed to lower intraocular pressure by creating a new drainage pathway for excess fluid in glaucoma patients.

Ximedica has been a prominent player in the medical device industry for over 30 years, offering comprehensive research, development, regulatory, and manufacturing services. The company specializes in device and systems design, employing a human-centered, vertically integrated approach to enhance product efficiency from conception to market delivery. Ximedica's experienced, cross-disciplinary teams address complex development challenges, enabling clients to explore new market opportunities and achieve award-winning designs while exceeding sales targets. The firm emphasizes quality and regulatory assurance, underscored by its ISO 13485:2003 certification, which reflects its commitment to maintaining high standards in medical device innovation.

CSA Medical, Inc., established in 1993 and headquartered in Baltimore, Maryland, specializes in the development and manufacturing of spray cryotherapy medical devices. Its primary product, truFreeze, utilizes cold liquid nitrogen to destroy unwanted tissue across dermatology, gynecology, and general surgery fields while promoting healthy tissue regrowth. CSA Medical also offers the Rapid AV Spray Kit to enhance truFreeze's efficiency. The company operates a research and development facility in Lexington, Massachusetts.

Soffio Medical, Inc. is a Boston-based company focused on developing innovative medical devices for respiratory diseases. The firm specializes in implantable technologies that aim to address chronic obstructive pulmonary disease (COPD) and similar conditions. Its devices are designed to implement an airway bypass concept, allowing for the venting of trapped air from areas distal to high-resistance airways. This approach helps reduce residual lung volume and alleviates symptoms associated with respiratory diseases, ultimately enhancing the quality of life for patients.

Oncoethix SA is a private Swiss company that was founded in 2007 by Esteban Cvitkovic, MD, Kay Noel, PhD, Yves Paternot, and Patrice Herait, MD (all former associates at Cvitkovic & Associes Consultants SA) to develop a portfolio of 3 to 5 promising new drugs for cancer treatment. The company intends to develop its compounds through clinical proof of concept and the identification of an expedited registration strategy, after which pharmaceutical partners will be sought to fund pivotal trials and handle commercialization. Oncoethix founders have an unsurpassed track record in identifying and bringing oncology leads to global markets. Dr. Cvitkovic, Chief Scientific Officer for Oncoethix, led the clinical development of single agent and combination regimens for cisplatin, vindesine, bleomycin, navelbine, and, more recently, irinotecan, oxaliplatin, docetaxel, and trabectedin, first as an academic investigator and then through a specialized oncology clinical research organization. Prior to founding Oncoethix and assuming responsibilities as Chief Operating Officer, Dr. Noel had co-founded another oncology drug development company which in-licensed oxaliplatin as its first portfolio product and subsequently identified, evaluated, and in-licensed novel agents for several clients. Additionally, Dr. Noel has developed expedited registration strategies for many cancer drugs and registration files for a few of these. Dr. Herait managed clinical development of irinotecan, from Phase 1 through Phase 3, while at Rhone Poulenc Rorer and subsequently, as a consultant, managed clinical studies for several novel cancer drugs. Since its founding, Oncoethix has in-licensed three promising cancer drug candidates, each a first-in-class agent to a novel target or with a novel mode of action. Currently, two portfolio compounds are in clinical development. Oncoethix was launched with an initial financing of 1.30 million Swiss francs from the founders to finance portfolio development. In December 2009, the company closed a Series A financing of 3.7 million Swiss francs with leading venture capital firms Index Ventures and Endeavour Vision.

CardioKinetix develops transcatheter implants for treating heart failure. Its flagship product is Parachute, a ventricular partitioning device designed to improve overall cardiac function in patients who have experienced a heart attack. The company serves customers primarily in the United States and Europe.

ReShape Lifesciences is a medical device company focused on technologies to treat obesity and metabolic diseases. The company develops and commercializes products designed to provide less invasive options for weight loss, including the Lap-Band System, an adjustable gastric banding device for long-term obesity management. It also has the ReShape Vest system, an investigational laparoscopically implanted device that wraps around the stomach and is designed to support weight loss without permanent changes to the GI tract; the Vest is primarily marketed outside the United States. The company traces its origins to EnteroMedics and adopted the ReShape Lifesciences name in 2017. It is headquartered in San Clemente, California, and operates in multiple international markets.

Cibiem Inc. is a medical device manufacturer specializing in Carotid Body Modulation (CBM), which targets sympathetic nervous system-mediated diseases such as hypertension, heart failure, diabetes, and renal failure. Founded in 2010 and based in Los Altos, California, with an additional office in Teaneck, New Jersey, Cibiem utilizes a proprietary, minimally invasive, catheter-based approach to deliver its treatments. The company was co-founded by Mark Gelfand and Howard R. Levin, M.D., who bring a wealth of experience in medical innovation and entrepreneurship. Cibiem aims to enhance the efficacy of medical interventions for serious health conditions, thereby improving patient outcomes in the treatment of these critical disorders.

Founded in 2005, Halscion specializes in developing biocompatible hydrogel scaffolds designed to improve wound healing and reduce scarring. These single-use devices are applied during surgeries at the dermal-subdermal interface of wounds by injection, allowing the patient's own cells to organize and propagate into the wound.

MindFrame, Inc., established in 2007 and headquartered in Irvine, California, specializes in developing innovative medical devices for treating ischemic stroke. Its flagship product is the MindFrame Capture LP device, designed to rapidly restore blood flow and extract clots, enabling clinicians to achieve improved patient outcomes. Additionally, MindFrame offers the MindFrame Capture for ICA-T and basilar arteries, MCA territory, and the MindFrame Flow system, which creates a bypass for faster delivery of thrombolytic agents. As of 2012, MindFrame operates as a subsidiary of Covidien plc.

Good Start Genetics, Inc. is a molecular diagnostics company based in Cambridge, Massachusetts, founded in 2007. It specializes in genetic screening for inherited diseases, aiming to transform reproductive medicine by providing actionable information to physicians and patients. The company offers a range of services, including EmbryVu, a preimplantation genetic screening test designed to enhance in vitro fertilization outcomes by identifying suitable embryos for implantation. Additionally, Good Start Genetics provides a comprehensive array of genetic carrier screening tests through its GoodStart Select program, utilizing advanced next-generation DNA sequencing technology along with other established genetic screening methods. This focus on high carrier detection rates and commitment to customer care and genetic counseling positions the company as a leader in the field of pre-pregnancy genetic testing and diagnostics. As of August 2017, Good Start Genetics operates as a subsidiary of Invitae Corporation.

CSA Medical, Inc., established in 1993 and headquartered in Baltimore, Maryland, specializes in the development and manufacturing of spray cryotherapy medical devices. Its primary product, truFreeze, utilizes cold liquid nitrogen to destroy unwanted tissue across dermatology, gynecology, and general surgery fields while promoting healthy tissue regrowth. CSA Medical also offers the Rapid AV Spray Kit to enhance truFreeze's efficiency. The company operates a research and development facility in Lexington, Massachusetts.

AcuFocus, Inc. is an ophthalmic medical device company based in Irvine, California, specializing in small aperture technologies aimed at improving near vision. Founded in 2001, the company develops and markets innovative solutions for presbyopia, including the KAMRA inlay, which helps patients restore their near vision without compromising distance vision. Additionally, AcuFocus offers the IC-8 IOL, a small aperture lens designed for cataract patients, providing a broad range of vision from near to far distances. The company also produces the AcuTarget HD, a diagnostic and surgical planning instrument that assists in the optimal treatment selection for various eye conditions such as LASIK, cataracts, and dry eye. AcuFocus distributes its products through partners across the Americas, Asia-Pacific, Europe, and the Middle East, serving both physicians and patients in the vision care market.

CardioKinetix develops transcatheter implants for treating heart failure. Its flagship product is Parachute, a ventricular partitioning device designed to improve overall cardiac function in patients who have experienced a heart attack. The company serves customers primarily in the United States and Europe.

Entellus Medical, doing business as Stryker ENT, is a medical device company based in Plymouth, Minnesota, specializing in innovative solutions for ear, nose, and throat (ENT) treatments. Founded in 2006, Entellus develops and commercializes minimally invasive products aimed at addressing chronic sinusitis, eustachian tube dysfunction, and nasal airway obstruction. Its product lineup includes the XprESS ENT dilation system, which offers versatility for sinus and eustachian tube procedures, and the FinESS Sinus Treatment, a direct and effective method for treating chronic rhinosinusitis that minimizes invasiveness and recovery time. The company also provides a range of surgical instruments, imaging solutions, and other tools that enhance patient care while reducing discomfort and the need for general anesthesia. By collaborating with researchers and clinicians, Entellus Medical works to meet the unmet needs of physicians and patients alike, thereby improving treatment outcomes in the ENT field.

Founded in 2005, Halscion specializes in developing biocompatible hydrogel scaffolds designed to improve wound healing and reduce scarring. These single-use devices are applied during surgeries at the dermal-subdermal interface of wounds by injection, allowing the patient's own cells to organize and propagate into the wound.

CardioFocus develops endoscopic ablation systems for atrial fibrillation, including the HeartLight Endoscopic Ablation System with direct visualization and energy-delivery capabilities for pulmonary vein isolation, as well as the HeartLight Excalibur Balloon and HeartLight X3 System for stable tissue contact and controlled lesion creation across varying pulmonary vein anatomies. The company integrates a balloon catheter, endoscope, deflectable sheath, and console to enable electrophysiologists to tailor ablations to patient needs. Founded in 1990 and based in Marlborough, Massachusetts, CardioFocus aims to advance treatment of cardiac arrhythmias through visualization-guided devices.

EBR Systems is a medical device company that develops implantable wireless tissue stimulation systems for cardiac rhythm management. It focuses on therapies for heart failure and cardiac arrhythmias, including a wireless left ventricular endocardial pacing system used to deliver pacing stimulation directly inside the left ventricle as part of cardiac resynchronization therapy. Founded in 2003 and headquartered in Sunnyvale, California, EBR Systems pursues novel approaches in the field and operates primarily in the United States.

Cibiem Inc. is a medical device manufacturer specializing in Carotid Body Modulation (CBM), which targets sympathetic nervous system-mediated diseases such as hypertension, heart failure, diabetes, and renal failure. Founded in 2010 and based in Los Altos, California, with an additional office in Teaneck, New Jersey, Cibiem utilizes a proprietary, minimally invasive, catheter-based approach to deliver its treatments. The company was co-founded by Mark Gelfand and Howard R. Levin, M.D., who bring a wealth of experience in medical innovation and entrepreneurship. Cibiem aims to enhance the efficacy of medical interventions for serious health conditions, thereby improving patient outcomes in the treatment of these critical disorders.

Good Start Genetics, Inc. is a molecular diagnostics company based in Cambridge, Massachusetts, founded in 2007. It specializes in genetic screening for inherited diseases, aiming to transform reproductive medicine by providing actionable information to physicians and patients. The company offers a range of services, including EmbryVu, a preimplantation genetic screening test designed to enhance in vitro fertilization outcomes by identifying suitable embryos for implantation. Additionally, Good Start Genetics provides a comprehensive array of genetic carrier screening tests through its GoodStart Select program, utilizing advanced next-generation DNA sequencing technology along with other established genetic screening methods. This focus on high carrier detection rates and commitment to customer care and genetic counseling positions the company as a leader in the field of pre-pregnancy genetic testing and diagnostics. As of August 2017, Good Start Genetics operates as a subsidiary of Invitae Corporation.

MindFrame, Inc., established in 2007 and headquartered in Irvine, California, specializes in developing innovative medical devices for treating ischemic stroke. Its flagship product is the MindFrame Capture LP device, designed to rapidly restore blood flow and extract clots, enabling clinicians to achieve improved patient outcomes. Additionally, MindFrame offers the MindFrame Capture for ICA-T and basilar arteries, MCA territory, and the MindFrame Flow system, which creates a bypass for faster delivery of thrombolytic agents. As of 2012, MindFrame operates as a subsidiary of Covidien plc.

Altura Medical, Inc. is a medical device company based in Menlo Park, California, focused on developing innovative endograft technology for the treatment of abdominal aortic aneurysms (AAA) and associated conditions. The company's flagship product, the Agili-D AAA System, represents a next-generation endovascular aneurysm repair solution designed to improve patient outcomes. Founded in 2008, Altura Medical has built a reputation for its differentiated technology, which is supported by a skilled management team and a network of prominent venture capital investors. As of 2015, Altura Medical operates as a subsidiary of Lombard Medical, Inc.

Founded in 2005, AqueSys specializes in developing and commercializing innovative ophthalmic devices. Its flagship product is the XEN gel stent, an implantable device designed to lower intraocular pressure by creating a new drainage pathway for excess fluid in glaucoma patients.

EBR Systems is a medical device company that develops implantable wireless tissue stimulation systems for cardiac rhythm management. It focuses on therapies for heart failure and cardiac arrhythmias, including a wireless left ventricular endocardial pacing system used to deliver pacing stimulation directly inside the left ventricle as part of cardiac resynchronization therapy. Founded in 2003 and headquartered in Sunnyvale, California, EBR Systems pursues novel approaches in the field and operates primarily in the United States.

Entellus Medical, doing business as Stryker ENT, is a medical device company based in Plymouth, Minnesota, specializing in innovative solutions for ear, nose, and throat (ENT) treatments. Founded in 2006, Entellus develops and commercializes minimally invasive products aimed at addressing chronic sinusitis, eustachian tube dysfunction, and nasal airway obstruction. Its product lineup includes the XprESS ENT dilation system, which offers versatility for sinus and eustachian tube procedures, and the FinESS Sinus Treatment, a direct and effective method for treating chronic rhinosinusitis that minimizes invasiveness and recovery time. The company also provides a range of surgical instruments, imaging solutions, and other tools that enhance patient care while reducing discomfort and the need for general anesthesia. By collaborating with researchers and clinicians, Entellus Medical works to meet the unmet needs of physicians and patients alike, thereby improving treatment outcomes in the ENT field.

Founded in 2005, Halscion specializes in developing biocompatible hydrogel scaffolds designed to improve wound healing and reduce scarring. These single-use devices are applied during surgeries at the dermal-subdermal interface of wounds by injection, allowing the patient's own cells to organize and propagate into the wound.

Asensus Surgical is a medical device company focused on enhancing minimally invasive surgery through digital laparoscopy. By digitizing the interface between surgeons and patients, the company incorporates advanced technologies such as augmented intelligence, connectivity, and robotics into surgical procedures. Their flagship product, the Senhance Surgical System, is notable for being the first machine vision system designed for robotic surgery. This system is supported by the Intelligent Surgical Unit, which facilitates augmented intelligence in surgery. Asensus Surgical aims to address various clinical, cognitive, and economic challenges faced in surgical practices, ultimately improving patient outcomes through innovative solutions in digital laparoscopy.

ValenTx, Inc. is a medical device company based in Maple Grove, Minnesota, that specializes in developing innovative therapy solutions for patients suffering from obesity and obesity-related metabolic disorders. Founded in 2002, ValenTx focuses on minimally-invasive treatment methods, including an endoluminal bypass therapy that replicates the anatomical changes of the traditional Roux-en-Y gastric bypass procedure. This technology features an adjustable, removable, and replaceable device designed to address conditions such as type-2 diabetes and hypertension, aiming to improve patient outcomes in the management of these chronic health issues.

Lux Biosciences, established in 2005 and headquartered in Jersey City, New Jersey, is a biotechnology company focused on developing innovative treatments for ophthalmic diseases. Its product pipeline includes LX201, an implantable device releasing cyclosporine A for extended periods; Luveniq, an oral calcineurin inhibitor voclosporin; LX212, a bioerodible polymer implant containing voclosporin; and LX214, a topical nanomicellar formulation of voclosporin for dry eye therapy. These products aim to address serious ophthalmic conditions, improving patient outcomes through effective and convenient treatment options.

Spinal Kinetics LLC is a medical device company based in Sunnyvale, California, founded in 2003. The company specializes in the design and development of non-fusion motion preservation systems for treating degenerative diseases of the cervical and lumbar spine. Its flagship products, the M6-C and M6-L artificial discs, offer innovative options for artificial cervical and lumbar disc replacements, respectively. These discs are uniquely engineered to replicate the anatomical and biomechanical properties of natural intervertebral discs by incorporating an artificial nucleus and annulus. Spinal Kinetics collaborates with spine surgeons to enhance the effectiveness of its devices, which are distributed in various countries, including Australia, Germany, Spain, and the United Kingdom. The company operates as a subsidiary of Orthofix Medical Inc.

Altura Medical, Inc. is a medical device company based in Menlo Park, California, focused on developing innovative endograft technology for the treatment of abdominal aortic aneurysms (AAA) and associated conditions. The company's flagship product, the Agili-D AAA System, represents a next-generation endovascular aneurysm repair solution designed to improve patient outcomes. Founded in 2008, Altura Medical has built a reputation for its differentiated technology, which is supported by a skilled management team and a network of prominent venture capital investors. As of 2015, Altura Medical operates as a subsidiary of Lombard Medical, Inc.

NovaLign Orthopaedics formerly known as OsteoLign is an orthopaedic medical device company based in Memphis, Tenn. NovaLign recently received its first 510(k) clearance from the FDA to market its new Intramedullary Fixation System, a new system of implants and instruments for the treatment of long bone fractures, including the humerus, tibia and femur.

LensX Lasers is a developer of surgical lasers used for the reparation of cataracts.

ReShape Lifesciences is a medical device company focused on technologies to treat obesity and metabolic diseases. The company develops and commercializes products designed to provide less invasive options for weight loss, including the Lap-Band System, an adjustable gastric banding device for long-term obesity management. It also has the ReShape Vest system, an investigational laparoscopically implanted device that wraps around the stomach and is designed to support weight loss without permanent changes to the GI tract; the Vest is primarily marketed outside the United States. The company traces its origins to EnteroMedics and adopted the ReShape Lifesciences name in 2017. It is headquartered in San Clemente, California, and operates in multiple international markets.

ReShape Lifesciences is a medical device company focused on technologies to treat obesity and metabolic diseases. The company develops and commercializes products designed to provide less invasive options for weight loss, including the Lap-Band System, an adjustable gastric banding device for long-term obesity management. It also has the ReShape Vest system, an investigational laparoscopically implanted device that wraps around the stomach and is designed to support weight loss without permanent changes to the GI tract; the Vest is primarily marketed outside the United States. The company traces its origins to EnteroMedics and adopted the ReShape Lifesciences name in 2017. It is headquartered in San Clemente, California, and operates in multiple international markets.

Concentric Medical, based in Mountain View, California, is a medical device company specializing in the design, development, and commercialization of minimally invasive devices for the neurovasculature. The company focuses on creating endovascular solutions aimed at revascularizing stroke patients, particularly those experiencing ischemic strokes. Its product offerings include innovative devices designed to restore blood flow by effectively removing blood clots from affected vessels in the brain. Notably, Concentric Medical has developed Merci microcatheters, which are engineered to navigate the complex vasculature to reach critical areas in need of intervention.

Cellutions is developing proprietary medical devices and procedures to treat cellulite, a condition that affects 90% of post-adolescent females. The company is developing a proprietary technology/procedure to be performed in an outpatient setting as a minimally invasive ‘lunchtime' treatment.

Altura Medical, Inc. is a medical device company based in Menlo Park, California, focused on developing innovative endograft technology for the treatment of abdominal aortic aneurysms (AAA) and associated conditions. The company's flagship product, the Agili-D AAA System, represents a next-generation endovascular aneurysm repair solution designed to improve patient outcomes. Founded in 2008, Altura Medical has built a reputation for its differentiated technology, which is supported by a skilled management team and a network of prominent venture capital investors. As of 2015, Altura Medical operates as a subsidiary of Lombard Medical, Inc.

Founded in 2005, AqueSys specializes in developing and commercializing innovative ophthalmic devices. Its flagship product is the XEN gel stent, an implantable device designed to lower intraocular pressure by creating a new drainage pathway for excess fluid in glaucoma patients.

EBR Systems is a medical device company that develops implantable wireless tissue stimulation systems for cardiac rhythm management. It focuses on therapies for heart failure and cardiac arrhythmias, including a wireless left ventricular endocardial pacing system used to deliver pacing stimulation directly inside the left ventricle as part of cardiac resynchronization therapy. Founded in 2003 and headquartered in Sunnyvale, California, EBR Systems pursues novel approaches in the field and operates primarily in the United States.

Entellus Medical, doing business as Stryker ENT, is a medical device company based in Plymouth, Minnesota, specializing in innovative solutions for ear, nose, and throat (ENT) treatments. Founded in 2006, Entellus develops and commercializes minimally invasive products aimed at addressing chronic sinusitis, eustachian tube dysfunction, and nasal airway obstruction. Its product lineup includes the XprESS ENT dilation system, which offers versatility for sinus and eustachian tube procedures, and the FinESS Sinus Treatment, a direct and effective method for treating chronic rhinosinusitis that minimizes invasiveness and recovery time. The company also provides a range of surgical instruments, imaging solutions, and other tools that enhance patient care while reducing discomfort and the need for general anesthesia. By collaborating with researchers and clinicians, Entellus Medical works to meet the unmet needs of physicians and patients alike, thereby improving treatment outcomes in the ENT field.

CardioMind, Inc. Inc manufactures therapeutic devices for cardiovascular diseases. The company also offers stent delivery systems, which are designed for use in lesion applications, as well as for the treatment of coronary and peripheral artery diseases. In addition, it provides invasive endovascular medical devices for treating neurological and cardiovascular diseases. The company was founded in 2003 and is based in Sunnyvale, California.

Asensus Surgical is a medical device company focused on enhancing minimally invasive surgery through digital laparoscopy. By digitizing the interface between surgeons and patients, the company incorporates advanced technologies such as augmented intelligence, connectivity, and robotics into surgical procedures. Their flagship product, the Senhance Surgical System, is notable for being the first machine vision system designed for robotic surgery. This system is supported by the Intelligent Surgical Unit, which facilitates augmented intelligence in surgery. Asensus Surgical aims to address various clinical, cognitive, and economic challenges faced in surgical practices, ultimately improving patient outcomes through innovative solutions in digital laparoscopy.

ReShape Lifesciences is a medical device company focused on technologies to treat obesity and metabolic diseases. The company develops and commercializes products designed to provide less invasive options for weight loss, including the Lap-Band System, an adjustable gastric banding device for long-term obesity management. It also has the ReShape Vest system, an investigational laparoscopically implanted device that wraps around the stomach and is designed to support weight loss without permanent changes to the GI tract; the Vest is primarily marketed outside the United States. The company traces its origins to EnteroMedics and adopted the ReShape Lifesciences name in 2017. It is headquartered in San Clemente, California, and operates in multiple international markets.

Founded in 2005, AqueSys specializes in developing and commercializing innovative ophthalmic devices. Its flagship product is the XEN gel stent, an implantable device designed to lower intraocular pressure by creating a new drainage pathway for excess fluid in glaucoma patients.

CardioMind, Inc. Inc manufactures therapeutic devices for cardiovascular diseases. The company also offers stent delivery systems, which are designed for use in lesion applications, as well as for the treatment of coronary and peripheral artery diseases. In addition, it provides invasive endovascular medical devices for treating neurological and cardiovascular diseases. The company was founded in 2003 and is based in Sunnyvale, California.

Cellutions is developing proprietary medical devices and procedures to treat cellulite, a condition that affects 90% of post-adolescent females. The company is developing a proprietary technology/procedure to be performed in an outpatient setting as a minimally invasive ‘lunchtime' treatment.

Entellus Medical, doing business as Stryker ENT, is a medical device company based in Plymouth, Minnesota, specializing in innovative solutions for ear, nose, and throat (ENT) treatments. Founded in 2006, Entellus develops and commercializes minimally invasive products aimed at addressing chronic sinusitis, eustachian tube dysfunction, and nasal airway obstruction. Its product lineup includes the XprESS ENT dilation system, which offers versatility for sinus and eustachian tube procedures, and the FinESS Sinus Treatment, a direct and effective method for treating chronic rhinosinusitis that minimizes invasiveness and recovery time. The company also provides a range of surgical instruments, imaging solutions, and other tools that enhance patient care while reducing discomfort and the need for general anesthesia. By collaborating with researchers and clinicians, Entellus Medical works to meet the unmet needs of physicians and patients alike, thereby improving treatment outcomes in the ENT field.

Quick Study Radiology provides digital imaging solutions for community hospitals, radiology and oncology practices, and imaging centers. The company offers image and data archiving, and disaster recovery services; monitoring and security services; and networking and web distribution services. It also provides picture archiving and communication systems for community hospitals and other facilities, and radiology information systems to store, manage, and distribute patient’s data and imagery. Quick Study Radiology was founded in 1999 and is based in Saint Louis, Missouri.

AcuFocus, Inc. is an ophthalmic medical device company based in Irvine, California, specializing in small aperture technologies aimed at improving near vision. Founded in 2001, the company develops and markets innovative solutions for presbyopia, including the KAMRA inlay, which helps patients restore their near vision without compromising distance vision. Additionally, AcuFocus offers the IC-8 IOL, a small aperture lens designed for cataract patients, providing a broad range of vision from near to far distances. The company also produces the AcuTarget HD, a diagnostic and surgical planning instrument that assists in the optimal treatment selection for various eye conditions such as LASIK, cataracts, and dry eye. AcuFocus distributes its products through partners across the Americas, Asia-Pacific, Europe, and the Middle East, serving both physicians and patients in the vision care market.

Neurotech is a biotechnology company focused on developing sight-saving therapeutics for chronic retinal diseases. Their innovative approach involves engineering an ocular implant that continuously produces therapeutic proteins, aiming to improve the quality of life for people with these conditions.

Entellus Medical, doing business as Stryker ENT, is a medical device company based in Plymouth, Minnesota, specializing in innovative solutions for ear, nose, and throat (ENT) treatments. Founded in 2006, Entellus develops and commercializes minimally invasive products aimed at addressing chronic sinusitis, eustachian tube dysfunction, and nasal airway obstruction. Its product lineup includes the XprESS ENT dilation system, which offers versatility for sinus and eustachian tube procedures, and the FinESS Sinus Treatment, a direct and effective method for treating chronic rhinosinusitis that minimizes invasiveness and recovery time. The company also provides a range of surgical instruments, imaging solutions, and other tools that enhance patient care while reducing discomfort and the need for general anesthesia. By collaborating with researchers and clinicians, Entellus Medical works to meet the unmet needs of physicians and patients alike, thereby improving treatment outcomes in the ENT field.

Spinal Kinetics LLC is a medical device company based in Sunnyvale, California, founded in 2003. The company specializes in the design and development of non-fusion motion preservation systems for treating degenerative diseases of the cervical and lumbar spine. Its flagship products, the M6-C and M6-L artificial discs, offer innovative options for artificial cervical and lumbar disc replacements, respectively. These discs are uniquely engineered to replicate the anatomical and biomechanical properties of natural intervertebral discs by incorporating an artificial nucleus and annulus. Spinal Kinetics collaborates with spine surgeons to enhance the effectiveness of its devices, which are distributed in various countries, including Australia, Germany, Spain, and the United Kingdom. The company operates as a subsidiary of Orthofix Medical Inc.