SOSV

Avalo is a plant biology company that employs interpretable machine learning, genomic discovery, and evolutionary theory to expedite the development of new crops tailored for future agricultural needs. Utilizing AI-assisted plant breeding methods, Avalo creates non-GMO products that foster natural biodiversity. Its core technology, a discovery engine, can swiftly identify genetic bases of complex traits even in understudied crops, reducing time and cost significantly compared to traditional methods. This enables Avalo to forecast and enhance crop traits like drought tolerance and nutrient density, adapting agriculture to changing climates.

Sun Genomics, Inc. is a microbiome health company based in San Diego, California, specializing in customized probiotics aimed at addressing dysbiosis. Founded in 2014, the company’s flagship product, Floré, combines a gut microbiome test with personalized probiotic formulations tailored to individual gut profiles, assessed through whole-genome sequencing. The Floré Gut Test includes a microflora collection kit, a comprehensive microflora profile analysis, and wellness consultations. Additionally, Sun Genomics offers Floré Tots, a probiotic solution designed for children up to age 12, which comes in a convenient powder form that can be easily mixed with beverages. The company sells its products online, providing an automatic renewal service to enhance customer convenience.

Synplexity is a biotechnology company located in New Castle, Delaware, specializing in mutational scanning and multiplexed gene synthesis through advanced artificial intelligence technology. The company operates a large-scale gene synthesis and proteomics discovery platform that utilizes microdroplets as microreactors. This innovative approach allows for the efficient creation of multiplex gene libraries, which have applications across various sectors, including therapeutics, biomanufacturing, agriculture, and climate systems. Synplexity aims to drive advancements in healthcare and other industries through its cutting-edge genetic technologies.

Gatehouse Bio is a biotech company based in Waltham, Massachusetts, founded in 2016. The company specializes in the development of therapies utilizing a novel bioinformatics platform that focuses on small ribonucleic acid (RNA) biomarkers. This platform is designed to classify patient samples with binary accuracy and identifies disease-associated mutations, enabling the creation of targeted therapeutics. By employing artificial intelligence, Gatehouse Bio aims to analyze small RNA genes and design oligonucleotides that can effectively counteract the effects of these mutations. Their research and development efforts target therapeutic areas with known heterogeneity, such as fibrosis, inflammation, and neurodegeneration, with the goal of unlocking the potential for improved patient outcomes through personalized medicine.

Avalo is a plant biology company that employs interpretable machine learning, genomic discovery, and evolutionary theory to expedite the development of new crops tailored for future agricultural needs. Utilizing AI-assisted plant breeding methods, Avalo creates non-GMO products that foster natural biodiversity. Its core technology, a discovery engine, can swiftly identify genetic bases of complex traits even in understudied crops, reducing time and cost significantly compared to traditional methods. This enables Avalo to forecast and enhance crop traits like drought tolerance and nutrient density, adapting agriculture to changing climates.

HelEx is a biotechnology company founded in 2021 and based in New York, specializing in genomic medicines tailored for renal indications. The company utilizes its proprietary genomics data and bioinformatics to develop, validate, and distribute therapy-specific guide RNAs (gRNAs). HelEx's innovative platform leverages data-driven deep-learning modeling, utilizing high-throughput next-generation sequencing data derived from CRISPR edits on human cell lines. This approach provides reliable predictions and allows for in-house validation, thereby facilitating the acceleration of drug discovery and the development of cell and gene therapies in the CRISPR-based market.

DropGenie is a biotechnology company based in Montreal, Canada, founded in 2018. The company specializes in developing connected hardware that automates gene editing processes, facilitating advances in genetic engineering. Its platform streamlines liquid handling and experimental conditions, thereby enhancing standardization and reproducibility in scientific research. By making gene editing more accessible and efficient, DropGenie aims to accelerate the pace of discovery in the life sciences, ultimately reducing costs for researchers while generating compatible scientific information.

Reactosome is a biotechnology company that develops synthetic nuclei for gene therapy. Its core product, a synthetic nucleus, operates continuously within cells, mimicking the natural nucleus to affect multiple genes simultaneously. This approach aims to enhance the safety and longevity of gene expression, thereby enabling the development of treatments for complex diseases such as cancer and age-related disorders.

Sun Genomics, Inc. is a microbiome health company based in San Diego, California, specializing in customized probiotics aimed at addressing dysbiosis. Founded in 2014, the company’s flagship product, Floré, combines a gut microbiome test with personalized probiotic formulations tailored to individual gut profiles, assessed through whole-genome sequencing. The Floré Gut Test includes a microflora collection kit, a comprehensive microflora profile analysis, and wellness consultations. Additionally, Sun Genomics offers Floré Tots, a probiotic solution designed for children up to age 12, which comes in a convenient powder form that can be easily mixed with beverages. The company sells its products online, providing an automatic renewal service to enhance customer convenience.

Gatehouse Bio is a biotech company based in Waltham, Massachusetts, founded in 2016. The company specializes in the development of therapies utilizing a novel bioinformatics platform that focuses on small ribonucleic acid (RNA) biomarkers. This platform is designed to classify patient samples with binary accuracy and identifies disease-associated mutations, enabling the creation of targeted therapeutics. By employing artificial intelligence, Gatehouse Bio aims to analyze small RNA genes and design oligonucleotides that can effectively counteract the effects of these mutations. Their research and development efforts target therapeutic areas with known heterogeneity, such as fibrosis, inflammation, and neurodegeneration, with the goal of unlocking the potential for improved patient outcomes through personalized medicine.

TippingPoint Biosciences is focused on developing innovative therapeutics that address diseases caused by defects in DNA packaging, with an emphasis on conditions such as cancer and neurodegenerative disorders. Utilizing a specialized drug discovery platform, the company aims to identify new treatment options that specifically target unique genome packaging states associated with various diseases. This approach not only facilitates the treatment of cancer but also holds potential for advancing stem cell therapies by correcting dysfunctional genome packaging. Through its research and development efforts, TippingPoint Biosciences seeks to provide effective solutions for complex medical challenges.

Pear Bio is a biotechnology company based in Boston and London that specializes in AI-enabled precision medicine for the treatment of challenging cancers. The company utilizes tumor biopsies and blood samples from cancer patients to identify new therapeutic targets through multi-omics analysis. Pear Bio's proprietary immune-microtumor platform allows for the testing of drug candidates directly on patient tumor samples, enhancing the efficacy of treatments. Additionally, the company employs a unique hydrogel technology that cultivates tumors outside the body, enabling the measurement of drug resistance and streamlining the treatment process. By focusing on tailored drug discovery and smarter combination therapies, Pear Bio aims to improve patient outcomes in cancer care.

DNALite Therapeutics, Inc. is a biopharmaceutical company focused on developing innovative gene therapy treatments for the gastrointestinal tract. Founded in 2016 and based in San Francisco, California, the company utilizes advanced oral lipid nanoparticle technology to deliver mRNA and plasmid DNA directly to intestinal stem cells. This approach aims to address the root causes of gastrointestinal diseases, including Familial Adenomatous Polyposis (FAP), a hereditary condition that can lead to colorectal cancer and often necessitates invasive surgical interventions. DNALite's therapies seek to transform protein biologics into oral drugs, allowing for more effective and less invasive treatment options.

Kolibri is a biotechnology company focused on revolutionizing large-scale cell culture to enhance accessibility and affordability in cell and gene therapies, as well as clean meat production. The company has developed a proprietary cell-engineering platform that employs advanced techniques in acoustics and biology, enabling its bioreactors to achieve a 90-fold increase in cell yield while significantly reducing production costs by up to 50 times. Kolibri's innovative bioreactors are designed to facilitate the efficient growth of cells at scale, thereby supporting partners in drug development and providing critical solutions for unlocking patient access to gene therapies and next-generation vaccines. Through its technological advancements, Kolibri aims to address key challenges in the bioproduction of biologics.

Renegade.bio is a biotechnology startup focused on the development and deployment of high-throughput diagnostics aimed at detecting novel infectious diseases. The company specializes in creating innovative diagnostics and assays that support drug development, utilizing advanced techniques such as biomarker discovery, polymerase chain reaction (PCR), next-generation sequencing (NGS), and liquid chromatography-mass spectrometry (LC-MS). By leveraging these capabilities, Renegade.bio enables healthcare organizations to offer diagnostic testing across various settings, including individuals, workplaces, schools, communities, and large events.

Pear Bio is a biotechnology company based in Boston and London that specializes in AI-enabled precision medicine for the treatment of challenging cancers. The company utilizes tumor biopsies and blood samples from cancer patients to identify new therapeutic targets through multi-omics analysis. Pear Bio's proprietary immune-microtumor platform allows for the testing of drug candidates directly on patient tumor samples, enhancing the efficacy of treatments. Additionally, the company employs a unique hydrogel technology that cultivates tumors outside the body, enabling the measurement of drug resistance and streamlining the treatment process. By focusing on tailored drug discovery and smarter combination therapies, Pear Bio aims to improve patient outcomes in cancer care.

Renegade.bio is a biotechnology startup focused on the development and deployment of high-throughput diagnostics aimed at detecting novel infectious diseases. The company specializes in creating innovative diagnostics and assays that support drug development, utilizing advanced techniques such as biomarker discovery, polymerase chain reaction (PCR), next-generation sequencing (NGS), and liquid chromatography-mass spectrometry (LC-MS). By leveraging these capabilities, Renegade.bio enables healthcare organizations to offer diagnostic testing across various settings, including individuals, workplaces, schools, communities, and large events.

Sun Genomics, Inc. is a microbiome health company based in San Diego, California, specializing in customized probiotics aimed at addressing dysbiosis. Founded in 2014, the company’s flagship product, Floré, combines a gut microbiome test with personalized probiotic formulations tailored to individual gut profiles, assessed through whole-genome sequencing. The Floré Gut Test includes a microflora collection kit, a comprehensive microflora profile analysis, and wellness consultations. Additionally, Sun Genomics offers Floré Tots, a probiotic solution designed for children up to age 12, which comes in a convenient powder form that can be easily mixed with beverages. The company sells its products online, providing an automatic renewal service to enhance customer convenience.

HelEx is a biotechnology company founded in 2021 and based in New York, specializing in genomic medicines tailored for renal indications. The company utilizes its proprietary genomics data and bioinformatics to develop, validate, and distribute therapy-specific guide RNAs (gRNAs). HelEx's innovative platform leverages data-driven deep-learning modeling, utilizing high-throughput next-generation sequencing data derived from CRISPR edits on human cell lines. This approach provides reliable predictions and allows for in-house validation, thereby facilitating the acceleration of drug discovery and the development of cell and gene therapies in the CRISPR-based market.

Gatehouse Bio is a biotech company based in Waltham, Massachusetts, founded in 2016. The company specializes in the development of therapies utilizing a novel bioinformatics platform that focuses on small ribonucleic acid (RNA) biomarkers. This platform is designed to classify patient samples with binary accuracy and identifies disease-associated mutations, enabling the creation of targeted therapeutics. By employing artificial intelligence, Gatehouse Bio aims to analyze small RNA genes and design oligonucleotides that can effectively counteract the effects of these mutations. Their research and development efforts target therapeutic areas with known heterogeneity, such as fibrosis, inflammation, and neurodegeneration, with the goal of unlocking the potential for improved patient outcomes through personalized medicine.

Sun Genomics, Inc. is a microbiome health company based in San Diego, California, specializing in customized probiotics aimed at addressing dysbiosis. Founded in 2014, the company’s flagship product, Floré, combines a gut microbiome test with personalized probiotic formulations tailored to individual gut profiles, assessed through whole-genome sequencing. The Floré Gut Test includes a microflora collection kit, a comprehensive microflora profile analysis, and wellness consultations. Additionally, Sun Genomics offers Floré Tots, a probiotic solution designed for children up to age 12, which comes in a convenient powder form that can be easily mixed with beverages. The company sells its products online, providing an automatic renewal service to enhance customer convenience.

SyntheX, Inc. is a biotechnology company based in San Francisco, California, founded in 2016. It operates a proprietary drug discovery platform that utilizes synthetic biology to expand the druggable proteome, focusing on therapeutic applications in oncology and rare diseases. The platform employs empirical intracellular selection to identify and design compounds that can modulate protein interactions, either disrupting specific protein-protein interactions or facilitating the targeted degradation of proteins through the recruitment of E3 ubiquitin ligases. SyntheX's development portfolio includes stabilized peptide therapeutics, such as STX101 and STX105, aimed at treating cancers that evade chemotherapy through homologous recombination. The company identifies drug targets by analyzing clinical, evolutionary, phenotypic, and structural data, and it maintains both internal oncology projects and collaborative discovery initiatives.

Briefcase Biotec develops KiloBaser, a Nespresso machine of DNA synthesis - enabling cutting edge research without detours. KiloBaser is a device for printing short synthetic DNA sequences. It enables individual scientists to easily produce the DNA they need on their desktops, while speeding up production of the basics for all genetic engineering and synthetic biology research and development. Headquartered in Graz, Steiermark, KiloBaser was founded in 2013 by Martin Jost and Alexander Murer.

Gatehouse Bio is a biotech company based in Waltham, Massachusetts, founded in 2016. The company specializes in the development of therapies utilizing a novel bioinformatics platform that focuses on small ribonucleic acid (RNA) biomarkers. This platform is designed to classify patient samples with binary accuracy and identifies disease-associated mutations, enabling the creation of targeted therapeutics. By employing artificial intelligence, Gatehouse Bio aims to analyze small RNA genes and design oligonucleotides that can effectively counteract the effects of these mutations. Their research and development efforts target therapeutic areas with known heterogeneity, such as fibrosis, inflammation, and neurodegeneration, with the goal of unlocking the potential for improved patient outcomes through personalized medicine.

AnimalBiome specializes in personalized nutrition services that focus on enhancing the gut health of dogs and cats through microbiome science. The company offers microbiome tests that assess the unique gut microbiota of individual pets, providing insights that inform tailored nutrition recommendations. Additionally, AnimalBiome develops restorative supplements made from material sourced from healthy animals, allowing for the introduction of beneficial microbes to help restore balance in the gut microbiome. By leveraging advanced diagnostic tools, including DNA sequencing, AnimalBiome enables pet owners to better understand their pets' gut health, ultimately contributing to improved well-being and a healthier lifestyle for their animals.

DNALite Therapeutics, Inc. is a biopharmaceutical company focused on developing innovative gene therapy treatments for the gastrointestinal tract. Founded in 2016 and based in San Francisco, California, the company utilizes advanced oral lipid nanoparticle technology to deliver mRNA and plasmid DNA directly to intestinal stem cells. This approach aims to address the root causes of gastrointestinal diseases, including Familial Adenomatous Polyposis (FAP), a hereditary condition that can lead to colorectal cancer and often necessitates invasive surgical interventions. DNALite's therapies seek to transform protein biologics into oral drugs, allowing for more effective and less invasive treatment options.

ArgenTAG is a biotechnology startup focused on revolutionizing genomic sequencing applications through proprietary technology. The company has developed a reliable and robust solution aimed at reducing the cost associated with long-read sequencers. ArgenTAG's platform integrates micro-fabrication, next-generation DNA sequencing, molecular biology, and mechanical engineering to create synthetic DNA barcodes. This innovation allows for the simultaneous sequencing of thousands of samples, enabling medical professionals to analyze antibodies and perform single-cell sequencing efficiently.

ArgenTAG is a biotechnology startup focused on revolutionizing genomic sequencing applications through proprietary technology. The company has developed a reliable and robust solution aimed at reducing the cost associated with long-read sequencers. ArgenTAG's platform integrates micro-fabrication, next-generation DNA sequencing, molecular biology, and mechanical engineering to create synthetic DNA barcodes. This innovation allows for the simultaneous sequencing of thousands of samples, enabling medical professionals to analyze antibodies and perform single-cell sequencing efficiently.

Inso Biosciences is an early-stage biotechnology company focused on developing innovative hardware platforms and tools for genomic sample handling. Utilizing patented microfluidic technology originally invented at Cornell University, Inso Biosciences enhances the efficiency of processing cellular material. The company's platform is designed to facilitate genomic analysis, including applications in long-read DNA extraction, multiomic sample processing, and pathogen surveillance. By enabling healthcare and biotechnology companies to effectively separate and isolate cellular components, Inso Biosciences aims to transform the landscape of biological sample preparation.

Circularis Biotechnologies, Inc. is a biotechnology company founded in 2014 and headquartered in Oakland, California. The company specializes in developing innovative methods to regulate gene expression, which enhances the production yields of biotherapeutics. Circularis offers a range of products, including RACRE Variant Libraries, hCMV Variant Library, Protein expression with CMV promoters, and T7 Variant Library. In addition, it provides various services such as RACRE Enhancement, RACRE Discovery, RACRE Technology Access Program, and Ribozyme Analysis of Cis-Regulatory Elements. Through its advanced technologies and services, Circularis aims to improve the efficiency and effectiveness of biotherapeutic production.

Gatehouse Bio is a biotech company based in Waltham, Massachusetts, founded in 2016. The company specializes in the development of therapies utilizing a novel bioinformatics platform that focuses on small ribonucleic acid (RNA) biomarkers. This platform is designed to classify patient samples with binary accuracy and identifies disease-associated mutations, enabling the creation of targeted therapeutics. By employing artificial intelligence, Gatehouse Bio aims to analyze small RNA genes and design oligonucleotides that can effectively counteract the effects of these mutations. Their research and development efforts target therapeutic areas with known heterogeneity, such as fibrosis, inflammation, and neurodegeneration, with the goal of unlocking the potential for improved patient outcomes through personalized medicine.

Sequential Skin is a diagnostic platform focused on skin longevity and aging, leveraging expertise in genetics, epigenetics, and the skin microbiome. The company specializes in clinical microbiome testing for skin, scalp, and female health. Its primary offering is a skin health test that employs quantitative real-time PCR (qPCR) technology to analyze specific markers within the skin microbiome. This analysis provides individuals with a detailed understanding of their skin profile, helping them identify their unique skincare needs. By delivering personalized insights, Sequential Skin empowers individuals to make informed decisions about their skincare routines.

DropGenie is a biotechnology company based in Montreal, Canada, founded in 2018. The company specializes in developing connected hardware that automates gene editing processes, facilitating advances in genetic engineering. Its platform streamlines liquid handling and experimental conditions, thereby enhancing standardization and reproducibility in scientific research. By making gene editing more accessible and efficient, DropGenie aims to accelerate the pace of discovery in the life sciences, ultimately reducing costs for researchers while generating compatible scientific information.

Catalog Technologies Inc. specializes in a DNA-based platform that revolutionizes digital data storage and computation. Founded in 2016 and headquartered in Boston, Massachusetts, the company provides a method for encoding digital information into DNA, making it a viable and cost-effective solution for long-term data archiving. By leveraging advanced synthetic biology technologies, Catalog aims to transform how information is stored, allowing customers to utilize DNA molecules as a primary medium for digital records. This innovative approach positions Catalog at the forefront of next-generation data storage solutions.

Indee Labs is focused on developing innovative hardware for gene delivery, specifically designed to facilitate the efficient development and scalable manufacture of gene-modified cell therapies, such as chimeric antigen receptor T cells. The company has created a non-viral intracellular delivery system that integrates with standard reagents, optimizing the recovery of viable modified cells with minimal disruption. Utilizing microfluidic vortex shedding technology, Indee Labs' system enables the gentle delivery of macromolecules, nucleic acids, and gene-editing complexes to various cell types. The company collaborates with the Australian National Fabrication Facility for its technology development and has established lab space at Bonneville Labs in Berkeley while expanding its operations with a new office in Sydney. Indee Labs has been associated with various prestigious incubators and programs, including NSW Health, IndieBio, Y Combinator, and MBC Biolabs.

Sequential Skin is a diagnostic platform focused on skin longevity and aging, leveraging expertise in genetics, epigenetics, and the skin microbiome. The company specializes in clinical microbiome testing for skin, scalp, and female health. Its primary offering is a skin health test that employs quantitative real-time PCR (qPCR) technology to analyze specific markers within the skin microbiome. This analysis provides individuals with a detailed understanding of their skin profile, helping them identify their unique skincare needs. By delivering personalized insights, Sequential Skin empowers individuals to make informed decisions about their skincare routines.

Pear Bio is a biotechnology company based in Boston and London that specializes in AI-enabled precision medicine for the treatment of challenging cancers. The company utilizes tumor biopsies and blood samples from cancer patients to identify new therapeutic targets through multi-omics analysis. Pear Bio's proprietary immune-microtumor platform allows for the testing of drug candidates directly on patient tumor samples, enhancing the efficacy of treatments. Additionally, the company employs a unique hydrogel technology that cultivates tumors outside the body, enabling the measurement of drug resistance and streamlining the treatment process. By focusing on tailored drug discovery and smarter combination therapies, Pear Bio aims to improve patient outcomes in cancer care.

HelEx is a biotechnology company founded in 2021 and based in New York, specializing in genomic medicines tailored for renal indications. The company utilizes its proprietary genomics data and bioinformatics to develop, validate, and distribute therapy-specific guide RNAs (gRNAs). HelEx's innovative platform leverages data-driven deep-learning modeling, utilizing high-throughput next-generation sequencing data derived from CRISPR edits on human cell lines. This approach provides reliable predictions and allows for in-house validation, thereby facilitating the acceleration of drug discovery and the development of cell and gene therapies in the CRISPR-based market.

HelEx is a biotechnology company founded in 2021 and based in New York, specializing in genomic medicines tailored for renal indications. The company utilizes its proprietary genomics data and bioinformatics to develop, validate, and distribute therapy-specific guide RNAs (gRNAs). HelEx's innovative platform leverages data-driven deep-learning modeling, utilizing high-throughput next-generation sequencing data derived from CRISPR edits on human cell lines. This approach provides reliable predictions and allows for in-house validation, thereby facilitating the acceleration of drug discovery and the development of cell and gene therapies in the CRISPR-based market.

Microgenesis is a biotechnology company focused on fertility and pregnancy health monitoring. It has developed a platform that provides a non-invasive fertility test and personalized nutritional supplementation aimed at restoring women's fertility potential. The company's innovative diagnostic approach detects subclinical inflammation that negatively impacts ovarian function and implantation, specifically targeting women who have experienced challenges, including multiple failed IVF attempts. Operating out of a CLIA lab in Oakland, Microgenesis offers its solutions through OB-GYNs and direct-to-consumer channels. Additionally, the platform addresses imbalances in vaginal and intestinal microbiota linked to infertility and offers dual testing for immunological issues related to the endometrium, equipping patients with effective treatment options for complex reproductive health cases.

Avalo is a plant biology company that employs interpretable machine learning, genomic discovery, and evolutionary theory to expedite the development of new crops tailored for future agricultural needs. Utilizing AI-assisted plant breeding methods, Avalo creates non-GMO products that foster natural biodiversity. Its core technology, a discovery engine, can swiftly identify genetic bases of complex traits even in understudied crops, reducing time and cost significantly compared to traditional methods. This enables Avalo to forecast and enhance crop traits like drought tolerance and nutrient density, adapting agriculture to changing climates.

Sequential Skin is a diagnostic platform focused on skin longevity and aging, leveraging expertise in genetics, epigenetics, and the skin microbiome. The company specializes in clinical microbiome testing for skin, scalp, and female health. Its primary offering is a skin health test that employs quantitative real-time PCR (qPCR) technology to analyze specific markers within the skin microbiome. This analysis provides individuals with a detailed understanding of their skin profile, helping them identify their unique skincare needs. By delivering personalized insights, Sequential Skin empowers individuals to make informed decisions about their skincare routines.

AnimalBiome specializes in personalized nutrition services that focus on enhancing the gut health of dogs and cats through microbiome science. The company offers microbiome tests that assess the unique gut microbiota of individual pets, providing insights that inform tailored nutrition recommendations. Additionally, AnimalBiome develops restorative supplements made from material sourced from healthy animals, allowing for the introduction of beneficial microbes to help restore balance in the gut microbiome. By leveraging advanced diagnostic tools, including DNA sequencing, AnimalBiome enables pet owners to better understand their pets' gut health, ultimately contributing to improved well-being and a healthier lifestyle for their animals.

DNALite Therapeutics, Inc. is a biopharmaceutical company focused on developing innovative gene therapy treatments for the gastrointestinal tract. Founded in 2016 and based in San Francisco, California, the company utilizes advanced oral lipid nanoparticle technology to deliver mRNA and plasmid DNA directly to intestinal stem cells. This approach aims to address the root causes of gastrointestinal diseases, including Familial Adenomatous Polyposis (FAP), a hereditary condition that can lead to colorectal cancer and often necessitates invasive surgical interventions. DNALite's therapies seek to transform protein biologics into oral drugs, allowing for more effective and less invasive treatment options.

Kolibri is a biotechnology company focused on revolutionizing large-scale cell culture to enhance accessibility and affordability in cell and gene therapies, as well as clean meat production. The company has developed a proprietary cell-engineering platform that employs advanced techniques in acoustics and biology, enabling its bioreactors to achieve a 90-fold increase in cell yield while significantly reducing production costs by up to 50 times. Kolibri's innovative bioreactors are designed to facilitate the efficient growth of cells at scale, thereby supporting partners in drug development and providing critical solutions for unlocking patient access to gene therapies and next-generation vaccines. Through its technological advancements, Kolibri aims to address key challenges in the bioproduction of biologics.

Wayfinder Biosciences is a biotechnology company focused on developing orally available small molecule drugs that target RNA to address key disease areas, including oncology and neurodegenerative disorders. Established in 2021 and headquartered in Seattle, WA, the company utilizes a proprietary platform that integrates advanced screening technologies and computational methods to discover potent and selective RNA-targeting molecules. By employing high-throughput screening combined with machine learning and unique datasets, Wayfinder aims to accelerate the development of therapeutics for traditionally inaccessible targets, enhancing the potential for treating genetic diseases and other challenging conditions.

Avalo is a plant biology company that employs interpretable machine learning, genomic discovery, and evolutionary theory to expedite the development of new crops tailored for future agricultural needs. Utilizing AI-assisted plant breeding methods, Avalo creates non-GMO products that foster natural biodiversity. Its core technology, a discovery engine, can swiftly identify genetic bases of complex traits even in understudied crops, reducing time and cost significantly compared to traditional methods. This enables Avalo to forecast and enhance crop traits like drought tolerance and nutrient density, adapting agriculture to changing climates.

Basin Genomics is combining scientific backgrounds in genomics and oncology with startup expertise to translate genetic discoveries into advances in personalized clinical care as it strives to develop technology that will decrease the rates of cervical cancer globally.

Basin Genomics is combining scientific backgrounds in genomics and oncology with startup expertise to translate genetic discoveries into advances in personalized clinical care as it strives to develop technology that will decrease the rates of cervical cancer globally.

Sequential Skin is a diagnostic platform focused on skin longevity and aging, leveraging expertise in genetics, epigenetics, and the skin microbiome. The company specializes in clinical microbiome testing for skin, scalp, and female health. Its primary offering is a skin health test that employs quantitative real-time PCR (qPCR) technology to analyze specific markers within the skin microbiome. This analysis provides individuals with a detailed understanding of their skin profile, helping them identify their unique skincare needs. By delivering personalized insights, Sequential Skin empowers individuals to make informed decisions about their skincare routines.

Microgenesis is a biotechnology company focused on fertility and pregnancy health monitoring. It has developed a platform that provides a non-invasive fertility test and personalized nutritional supplementation aimed at restoring women's fertility potential. The company's innovative diagnostic approach detects subclinical inflammation that negatively impacts ovarian function and implantation, specifically targeting women who have experienced challenges, including multiple failed IVF attempts. Operating out of a CLIA lab in Oakland, Microgenesis offers its solutions through OB-GYNs and direct-to-consumer channels. Additionally, the platform addresses imbalances in vaginal and intestinal microbiota linked to infertility and offers dual testing for immunological issues related to the endometrium, equipping patients with effective treatment options for complex reproductive health cases.

Gatehouse Bio is a biotech company based in Waltham, Massachusetts, founded in 2016. The company specializes in the development of therapies utilizing a novel bioinformatics platform that focuses on small ribonucleic acid (RNA) biomarkers. This platform is designed to classify patient samples with binary accuracy and identifies disease-associated mutations, enabling the creation of targeted therapeutics. By employing artificial intelligence, Gatehouse Bio aims to analyze small RNA genes and design oligonucleotides that can effectively counteract the effects of these mutations. Their research and development efforts target therapeutic areas with known heterogeneity, such as fibrosis, inflammation, and neurodegeneration, with the goal of unlocking the potential for improved patient outcomes through personalized medicine.

Gatehouse Bio is a biotech company based in Waltham, Massachusetts, founded in 2016. The company specializes in the development of therapies utilizing a novel bioinformatics platform that focuses on small ribonucleic acid (RNA) biomarkers. This platform is designed to classify patient samples with binary accuracy and identifies disease-associated mutations, enabling the creation of targeted therapeutics. By employing artificial intelligence, Gatehouse Bio aims to analyze small RNA genes and design oligonucleotides that can effectively counteract the effects of these mutations. Their research and development efforts target therapeutic areas with known heterogeneity, such as fibrosis, inflammation, and neurodegeneration, with the goal of unlocking the potential for improved patient outcomes through personalized medicine.

Pear Bio is a biotechnology company based in Boston and London that specializes in AI-enabled precision medicine for the treatment of challenging cancers. The company utilizes tumor biopsies and blood samples from cancer patients to identify new therapeutic targets through multi-omics analysis. Pear Bio's proprietary immune-microtumor platform allows for the testing of drug candidates directly on patient tumor samples, enhancing the efficacy of treatments. Additionally, the company employs a unique hydrogel technology that cultivates tumors outside the body, enabling the measurement of drug resistance and streamlining the treatment process. By focusing on tailored drug discovery and smarter combination therapies, Pear Bio aims to improve patient outcomes in cancer care.

Biomage is a company dedicated to advancing life sciences through innovative single-cell analysis. It offers a platform that enables researchers to analyze vast single-cell sequencing data efficiently, transforming complex biological data into actionable insights. This capability supports both academic and industrial scientists in enhancing drug target discovery while reducing costs. The Biomage Single Cell Platform allows users to manage their single-cell data analysis with ease, providing deep biological insights in a streamlined manner. By applying advanced computational methods, Biomage is at the forefront of facilitating groundbreaking research across various biological disciplines.

Renegade.bio is a biotechnology startup focused on the development and deployment of high-throughput diagnostics aimed at detecting novel infectious diseases. The company specializes in creating innovative diagnostics and assays that support drug development, utilizing advanced techniques such as biomarker discovery, polymerase chain reaction (PCR), next-generation sequencing (NGS), and liquid chromatography-mass spectrometry (LC-MS). By leveraging these capabilities, Renegade.bio enables healthcare organizations to offer diagnostic testing across various settings, including individuals, workplaces, schools, communities, and large events.

Synthetix is a decentralized synthetic asset issuance protocol based in Australia, established in 2017 by Kain Warwick. Built on the Ethereum blockchain, it facilitates derivatives trading in decentralized finance (DeFi) by enabling the creation of synthetic assets that provide exposure to real-world currencies, commodities, stocks, and indices. The platform offers unique financial instruments such as perpetual futures and options markets, allowing users to trade synthetic forms of assets with infinite liquidity. Synthetix operates a peer-to-contract trading system and utilizes a distributed collateral pool, ensuring transparency and accessibility for customers seeking on-chain exposure to various decentralized assets.

Microgenesis is a biotechnology company focused on fertility and pregnancy health monitoring. It has developed a platform that provides a non-invasive fertility test and personalized nutritional supplementation aimed at restoring women's fertility potential. The company's innovative diagnostic approach detects subclinical inflammation that negatively impacts ovarian function and implantation, specifically targeting women who have experienced challenges, including multiple failed IVF attempts. Operating out of a CLIA lab in Oakland, Microgenesis offers its solutions through OB-GYNs and direct-to-consumer channels. Additionally, the platform addresses imbalances in vaginal and intestinal microbiota linked to infertility and offers dual testing for immunological issues related to the endometrium, equipping patients with effective treatment options for complex reproductive health cases.

Pear Bio is a biotechnology company based in Boston and London that specializes in AI-enabled precision medicine for the treatment of challenging cancers. The company utilizes tumor biopsies and blood samples from cancer patients to identify new therapeutic targets through multi-omics analysis. Pear Bio's proprietary immune-microtumor platform allows for the testing of drug candidates directly on patient tumor samples, enhancing the efficacy of treatments. Additionally, the company employs a unique hydrogel technology that cultivates tumors outside the body, enabling the measurement of drug resistance and streamlining the treatment process. By focusing on tailored drug discovery and smarter combination therapies, Pear Bio aims to improve patient outcomes in cancer care.

AnimalBiome specializes in personalized nutrition services that focus on enhancing the gut health of dogs and cats through microbiome science. The company offers microbiome tests that assess the unique gut microbiota of individual pets, providing insights that inform tailored nutrition recommendations. Additionally, AnimalBiome develops restorative supplements made from material sourced from healthy animals, allowing for the introduction of beneficial microbes to help restore balance in the gut microbiome. By leveraging advanced diagnostic tools, including DNA sequencing, AnimalBiome enables pet owners to better understand their pets' gut health, ultimately contributing to improved well-being and a healthier lifestyle for their animals.

Sun Genomics, Inc. is a microbiome health company based in San Diego, California, specializing in customized probiotics aimed at addressing dysbiosis. Founded in 2014, the company’s flagship product, Floré, combines a gut microbiome test with personalized probiotic formulations tailored to individual gut profiles, assessed through whole-genome sequencing. The Floré Gut Test includes a microflora collection kit, a comprehensive microflora profile analysis, and wellness consultations. Additionally, Sun Genomics offers Floré Tots, a probiotic solution designed for children up to age 12, which comes in a convenient powder form that can be easily mixed with beverages. The company sells its products online, providing an automatic renewal service to enhance customer convenience.

Renegade.bio is a biotechnology startup focused on the development and deployment of high-throughput diagnostics aimed at detecting novel infectious diseases. The company specializes in creating innovative diagnostics and assays that support drug development, utilizing advanced techniques such as biomarker discovery, polymerase chain reaction (PCR), next-generation sequencing (NGS), and liquid chromatography-mass spectrometry (LC-MS). By leveraging these capabilities, Renegade.bio enables healthcare organizations to offer diagnostic testing across various settings, including individuals, workplaces, schools, communities, and large events.

DropGenie is a biotechnology company based in Montreal, Canada, founded in 2018. The company specializes in developing connected hardware that automates gene editing processes, facilitating advances in genetic engineering. Its platform streamlines liquid handling and experimental conditions, thereby enhancing standardization and reproducibility in scientific research. By making gene editing more accessible and efficient, DropGenie aims to accelerate the pace of discovery in the life sciences, ultimately reducing costs for researchers while generating compatible scientific information.

Biomage is a company dedicated to advancing life sciences through innovative single-cell analysis. It offers a platform that enables researchers to analyze vast single-cell sequencing data efficiently, transforming complex biological data into actionable insights. This capability supports both academic and industrial scientists in enhancing drug target discovery while reducing costs. The Biomage Single Cell Platform allows users to manage their single-cell data analysis with ease, providing deep biological insights in a streamlined manner. By applying advanced computational methods, Biomage is at the forefront of facilitating groundbreaking research across various biological disciplines.

Renegade.bio is a biotechnology startup focused on the development and deployment of high-throughput diagnostics aimed at detecting novel infectious diseases. The company specializes in creating innovative diagnostics and assays that support drug development, utilizing advanced techniques such as biomarker discovery, polymerase chain reaction (PCR), next-generation sequencing (NGS), and liquid chromatography-mass spectrometry (LC-MS). By leveraging these capabilities, Renegade.bio enables healthcare organizations to offer diagnostic testing across various settings, including individuals, workplaces, schools, communities, and large events.

Ivy Natal is a biotechnology company focused on addressing infertility through innovative reproductive solutions. The company has developed a skin biopsy technology that enables the creation of human egg cells from skin samples. This process activates the existing DNA within skin cells to transform them into healthy egg cells, offering a novel alternative to traditional in vitro methods for producing eggs and sperm. By circumventing the challenges associated with conventional reproductive techniques, Ivy Natal aims to provide couples, including those in same-sex relationships, with the opportunity to have genetically related children.

Circularis Biotechnologies, Inc. is a biotechnology company founded in 2014 and headquartered in Oakland, California. The company specializes in developing innovative methods to regulate gene expression, which enhances the production yields of biotherapeutics. Circularis offers a range of products, including RACRE Variant Libraries, hCMV Variant Library, Protein expression with CMV promoters, and T7 Variant Library. In addition, it provides various services such as RACRE Enhancement, RACRE Discovery, RACRE Technology Access Program, and Ribozyme Analysis of Cis-Regulatory Elements. Through its advanced technologies and services, Circularis aims to improve the efficiency and effectiveness of biotherapeutic production.

Pear Bio is a biotechnology company based in Boston and London that specializes in AI-enabled precision medicine for the treatment of challenging cancers. The company utilizes tumor biopsies and blood samples from cancer patients to identify new therapeutic targets through multi-omics analysis. Pear Bio's proprietary immune-microtumor platform allows for the testing of drug candidates directly on patient tumor samples, enhancing the efficacy of treatments. Additionally, the company employs a unique hydrogel technology that cultivates tumors outside the body, enabling the measurement of drug resistance and streamlining the treatment process. By focusing on tailored drug discovery and smarter combination therapies, Pear Bio aims to improve patient outcomes in cancer care.

Briefcase Biotec develops KiloBaser, a Nespresso machine of DNA synthesis - enabling cutting edge research without detours. KiloBaser is a device for printing short synthetic DNA sequences. It enables individual scientists to easily produce the DNA they need on their desktops, while speeding up production of the basics for all genetic engineering and synthetic biology research and development. Headquartered in Graz, Steiermark, KiloBaser was founded in 2013 by Martin Jost and Alexander Murer.

Catalog Technologies Inc. specializes in a DNA-based platform that revolutionizes digital data storage and computation. Founded in 2016 and headquartered in Boston, Massachusetts, the company provides a method for encoding digital information into DNA, making it a viable and cost-effective solution for long-term data archiving. By leveraging advanced synthetic biology technologies, Catalog aims to transform how information is stored, allowing customers to utilize DNA molecules as a primary medium for digital records. This innovative approach positions Catalog at the forefront of next-generation data storage solutions.

Renegade.bio is a biotechnology startup focused on the development and deployment of high-throughput diagnostics aimed at detecting novel infectious diseases. The company specializes in creating innovative diagnostics and assays that support drug development, utilizing advanced techniques such as biomarker discovery, polymerase chain reaction (PCR), next-generation sequencing (NGS), and liquid chromatography-mass spectrometry (LC-MS). By leveraging these capabilities, Renegade.bio enables healthcare organizations to offer diagnostic testing across various settings, including individuals, workplaces, schools, communities, and large events.

Farma Genetix is a Boston-based company that specializes in manufacturing genetically tailored natural supplements and personalized diet plans aimed at addressing chronic health conditions. By collaborating with researchers from Harvard Medical School's Genomics department, Farma Genetix develops nutritional products designed to support cardiovascular health, including the maintenance of healthy blood pressure and cholesterol levels. The company emphasizes the importance of a customized dietary approach to promote overall well-being and reinforce a healthy lifestyle.

Sun Genomics, Inc. is a microbiome health company based in San Diego, California, specializing in customized probiotics aimed at addressing dysbiosis. Founded in 2014, the company’s flagship product, Floré, combines a gut microbiome test with personalized probiotic formulations tailored to individual gut profiles, assessed through whole-genome sequencing. The Floré Gut Test includes a microflora collection kit, a comprehensive microflora profile analysis, and wellness consultations. Additionally, Sun Genomics offers Floré Tots, a probiotic solution designed for children up to age 12, which comes in a convenient powder form that can be easily mixed with beverages. The company sells its products online, providing an automatic renewal service to enhance customer convenience.

Pando Nutrition, Inc., founded in 2017 and headquartered in San Francisco, California, is an animal microbiome company focused on developing probiotics to promote livestock health and performance without relying on medically significant drugs. The company's primary goal is to address the antibiotic resistance crisis by engineering genetically modified probiotics that enhance feed efficiency, profitability, and methane emission control. Pando Nutrition offers Panbiotics, a platform designed to identify and manage methane emissions, thereby improving feed efficiency and livestock growth. Additionally, the company develops solutions for poultry pathogens like Coccidiosis and operates in the sustainable protein sector using yeast-based systems for animal feed.

Ravata Solutions is a medical device company based in Davis, California, specializing in gene delivery systems aimed at enhancing the development of custom animal models. Founded in 2016, Ravata focuses on improving the production of transgenic models that are crucial for pre-clinical research studies. By streamlining the creation of transgenic organisms and optimizing embryo viability, the company aims to accelerate human disease model development, thereby contributing to advancements in drug efficacy and medical genetics research. Through its innovative solutions, Ravata facilitates efficient embryo engineering at a production scale, ultimately supporting researchers in their efforts to understand and address complex health challenges.

Dahlia Biosciences is a biotechnology company founded in 2011 and headquartered in California, United States. It specializes in DNA analysis and diagnostics, focusing on the development of RNA detection tools that facilitate precision medicine research. The company's innovative solutions utilize CRISPR-Cas9 technology to detect multiple DNA and RNA biomarkers directly within cells and tissues. This capability allows researchers to study and isolate cells with high resolution, significantly enhancing the sensitivity and robustness of RNA detection in various applications. Dahlia Biosciences aims to advance research and diagnostic capabilities in the life sciences through its cutting-edge technologies.

DNALite Therapeutics, Inc. is a biopharmaceutical company focused on developing innovative gene therapy treatments for the gastrointestinal tract. Founded in 2016 and based in San Francisco, California, the company utilizes advanced oral lipid nanoparticle technology to deliver mRNA and plasmid DNA directly to intestinal stem cells. This approach aims to address the root causes of gastrointestinal diseases, including Familial Adenomatous Polyposis (FAP), a hereditary condition that can lead to colorectal cancer and often necessitates invasive surgical interventions. DNALite's therapies seek to transform protein biologics into oral drugs, allowing for more effective and less invasive treatment options.

DropGenie is a biotechnology company based in Montreal, Canada, founded in 2018. The company specializes in developing connected hardware that automates gene editing processes, facilitating advances in genetic engineering. Its platform streamlines liquid handling and experimental conditions, thereby enhancing standardization and reproducibility in scientific research. By making gene editing more accessible and efficient, DropGenie aims to accelerate the pace of discovery in the life sciences, ultimately reducing costs for researchers while generating compatible scientific information.

Serenity Bioworks is a biotechnology company focused on developing innovative antibody mimetics for targeted protein degradation. The company employs advanced display techniques alongside computational methods to optimize the discovery process of these therapeutics. Additionally, Serenity Bioworks is engaged in creating gene therapies aimed at addressing underserved areas in healthcare, such as hemophilia, inherited retinal diseases, and neurodegenerative conditions. Their goal is to enhance the long-term efficacy and safety profiles of gene therapy treatments, ultimately improving patient outcomes with safer and more durable solutions.

Helixworks Technologies, established in 2016 and headquartered in Cork, Ireland, specializes in biotechnology. The company manufactures molecular storage systems, utilizing DNA (Deoxyribonucleic acid) as a medium to store digital information. Their open architecture platform aims to simplify and streamline this process, making it accessible to developers working on applications such as digital preservation, molecular tagging, and advanced barcoding for Next-Generation Sequencing (NGS). Helixworks' mission is to transition biology into an engineering principle, ultimately enabling the creation of living machines.

Chronomics Ltd is a tech-bio company headquartered in Norwich, United Kingdom, that specializes in developing testing kits and an artificial intelligence platform for DNA methylation analysis. Founded in 2017, the company provides insights into biological age, smoke exposure, and metabolic state, as well as health risks, eye color, and hereditary intolerances. Chronomics aims to make biological information accessible and actionable, simplifying the use of biomarkers across various sectors, including telehealth, travel, and personal care. By partnering with major organizations, Chronomics seeks to enhance how individuals diagnose and personalize their health and wellness decisions, contributing to a broader bio-revolution that aims to transform everyday life through scientific innovation.

Sun Genomics, Inc. is a microbiome health company based in San Diego, California, specializing in customized probiotics aimed at addressing dysbiosis. Founded in 2014, the company’s flagship product, Floré, combines a gut microbiome test with personalized probiotic formulations tailored to individual gut profiles, assessed through whole-genome sequencing. The Floré Gut Test includes a microflora collection kit, a comprehensive microflora profile analysis, and wellness consultations. Additionally, Sun Genomics offers Floré Tots, a probiotic solution designed for children up to age 12, which comes in a convenient powder form that can be easily mixed with beverages. The company sells its products online, providing an automatic renewal service to enhance customer convenience.

Briefcase Biotec develops KiloBaser, a Nespresso machine of DNA synthesis - enabling cutting edge research without detours. KiloBaser is a device for printing short synthetic DNA sequences. It enables individual scientists to easily produce the DNA they need on their desktops, while speeding up production of the basics for all genetic engineering and synthetic biology research and development. Headquartered in Graz, Steiermark, KiloBaser was founded in 2013 by Martin Jost and Alexander Murer.

Dahlia Biosciences is a biotechnology company founded in 2011 and headquartered in California, United States. It specializes in DNA analysis and diagnostics, focusing on the development of RNA detection tools that facilitate precision medicine research. The company's innovative solutions utilize CRISPR-Cas9 technology to detect multiple DNA and RNA biomarkers directly within cells and tissues. This capability allows researchers to study and isolate cells with high resolution, significantly enhancing the sensitivity and robustness of RNA detection in various applications. Dahlia Biosciences aims to advance research and diagnostic capabilities in the life sciences through its cutting-edge technologies.

DNALite Therapeutics, Inc. is a biopharmaceutical company focused on developing innovative gene therapy treatments for the gastrointestinal tract. Founded in 2016 and based in San Francisco, California, the company utilizes advanced oral lipid nanoparticle technology to deliver mRNA and plasmid DNA directly to intestinal stem cells. This approach aims to address the root causes of gastrointestinal diseases, including Familial Adenomatous Polyposis (FAP), a hereditary condition that can lead to colorectal cancer and often necessitates invasive surgical interventions. DNALite's therapies seek to transform protein biologics into oral drugs, allowing for more effective and less invasive treatment options.

AnimalBiome specializes in personalized nutrition services that focus on enhancing the gut health of dogs and cats through microbiome science. The company offers microbiome tests that assess the unique gut microbiota of individual pets, providing insights that inform tailored nutrition recommendations. Additionally, AnimalBiome develops restorative supplements made from material sourced from healthy animals, allowing for the introduction of beneficial microbes to help restore balance in the gut microbiome. By leveraging advanced diagnostic tools, including DNA sequencing, AnimalBiome enables pet owners to better understand their pets' gut health, ultimately contributing to improved well-being and a healthier lifestyle for their animals.

Osiris Bio

Serenity Bioworks is a biotechnology company focused on developing innovative antibody mimetics for targeted protein degradation. The company employs advanced display techniques alongside computational methods to optimize the discovery process of these therapeutics. Additionally, Serenity Bioworks is engaged in creating gene therapies aimed at addressing underserved areas in healthcare, such as hemophilia, inherited retinal diseases, and neurodegenerative conditions. Their goal is to enhance the long-term efficacy and safety profiles of gene therapy treatments, ultimately improving patient outcomes with safer and more durable solutions.

Biomathematica is a biotechnology start-up focused on providing advanced modeling services to analyze and understand biological processes. The company specializes in developing innovative genome-scale metabolic models that facilitate the simulation, monitoring, control, optimization, and modification of biological behaviors. By concentrating on microbiome-related genomic data analysis, Biomathematica offers quantitative and predictive insights that support biotechnology and pharmaceutical companies in their exploration of microbiome-related therapeutics and disease areas. Through its expertise in mathematical modeling and simulation, Biomathematica aims to enhance the understanding of complex biological interactions, from genome to microbiome and cell interactions, ultimately improving decision-making and outcomes in various biotechnological applications.

Chronomics Ltd is a tech-bio company headquartered in Norwich, United Kingdom, that specializes in developing testing kits and an artificial intelligence platform for DNA methylation analysis. Founded in 2017, the company provides insights into biological age, smoke exposure, and metabolic state, as well as health risks, eye color, and hereditary intolerances. Chronomics aims to make biological information accessible and actionable, simplifying the use of biomarkers across various sectors, including telehealth, travel, and personal care. By partnering with major organizations, Chronomics seeks to enhance how individuals diagnose and personalize their health and wellness decisions, contributing to a broader bio-revolution that aims to transform everyday life through scientific innovation.

Sun Genomics, Inc. is a microbiome health company based in San Diego, California, specializing in customized probiotics aimed at addressing dysbiosis. Founded in 2014, the company’s flagship product, Floré, combines a gut microbiome test with personalized probiotic formulations tailored to individual gut profiles, assessed through whole-genome sequencing. The Floré Gut Test includes a microflora collection kit, a comprehensive microflora profile analysis, and wellness consultations. Additionally, Sun Genomics offers Floré Tots, a probiotic solution designed for children up to age 12, which comes in a convenient powder form that can be easily mixed with beverages. The company sells its products online, providing an automatic renewal service to enhance customer convenience.

Cell-Free Technology Limited, founded in 2017 and based in Cork, Ireland, specializes in creating cell-free extracts that enable the production of essential biomolecules, including insulin, odors, bio-compatible color palettes, and fluorescent proteins. The company focuses on cell-free protein expression, which allows for biological processes to occur outside of traditional laboratory settings, free from constraints posed by biological or GMO regulations. By offering ultra low-cost cell-free extracts and kits, Cell-Free Technology aims to democratize access to biological creation, facilitating innovation in various fields. The company is also committed to open-source projects, actively sharing resources and knowledge to broaden the application of its technologies.

Dahlia Biosciences is a biotechnology company founded in 2011 and headquartered in California, United States. It specializes in DNA analysis and diagnostics, focusing on the development of RNA detection tools that facilitate precision medicine research. The company's innovative solutions utilize CRISPR-Cas9 technology to detect multiple DNA and RNA biomarkers directly within cells and tissues. This capability allows researchers to study and isolate cells with high resolution, significantly enhancing the sensitivity and robustness of RNA detection in various applications. Dahlia Biosciences aims to advance research and diagnostic capabilities in the life sciences through its cutting-edge technologies.

Onconetics Pharmaceuticals, Inc. is a biotechnology company focused on developing gene therapies aimed at treating cancer and other genetic disorders. Established in 2016 and located in Mill Valley, California, Onconetics utilizes a unique therapeutic platform that incorporates a genetic switch to activate apoptotic inducers, selectively targeting tumor cells while preserving healthy tissue. The company is dedicated to advancing personalized medicine by integrating established gene therapy techniques with innovative research, striving to create effective treatments that reduce the invasiveness and side effects associated with traditional cancer therapies. Through its efforts, Onconetics aims to enhance patient outcomes and improve the overall quality of life for individuals affected by cancer and genetic conditions.

PLANTeDIT Limited is a biotech company headquartered in Cork, Ireland, established in 2017. It specializes in developing plant transformation technology systems that utilize CRISPR/Cas9 RNPs for direct genome editing in a variety of crop species. The company focuses on producing non-transgenic, regulatory-free, and sustainable plant products, such as high oleic soya, aimed at health-conscious consumers. Additionally, PLANTeDIT is engaged in creating mammalian proteins and human pharmaceuticals through its innovative genome-edited plant platform, which allows for the efficient production of cost-effective biopharmaceuticals. The company's commitment to sustainability and consumer-oriented solutions positions it as a leader in the advancement of genome editing technology in agriculture and biomedicine.

Catalog Technologies Inc. specializes in a DNA-based platform that revolutionizes digital data storage and computation. Founded in 2016 and headquartered in Boston, Massachusetts, the company provides a method for encoding digital information into DNA, making it a viable and cost-effective solution for long-term data archiving. By leveraging advanced synthetic biology technologies, Catalog aims to transform how information is stored, allowing customers to utilize DNA molecules as a primary medium for digital records. This innovative approach positions Catalog at the forefront of next-generation data storage solutions.

Indee Labs is focused on developing innovative hardware for gene delivery, specifically designed to facilitate the efficient development and scalable manufacture of gene-modified cell therapies, such as chimeric antigen receptor T cells. The company has created a non-viral intracellular delivery system that integrates with standard reagents, optimizing the recovery of viable modified cells with minimal disruption. Utilizing microfluidic vortex shedding technology, Indee Labs' system enables the gentle delivery of macromolecules, nucleic acids, and gene-editing complexes to various cell types. The company collaborates with the Australian National Fabrication Facility for its technology development and has established lab space at Bonneville Labs in Berkeley while expanding its operations with a new office in Sydney. Indee Labs has been associated with various prestigious incubators and programs, including NSW Health, IndieBio, Y Combinator, and MBC Biolabs.

Cell-Free Technology Limited, founded in 2017 and based in Cork, Ireland, specializes in creating cell-free extracts that enable the production of essential biomolecules, including insulin, odors, bio-compatible color palettes, and fluorescent proteins. The company focuses on cell-free protein expression, which allows for biological processes to occur outside of traditional laboratory settings, free from constraints posed by biological or GMO regulations. By offering ultra low-cost cell-free extracts and kits, Cell-Free Technology aims to democratize access to biological creation, facilitating innovation in various fields. The company is also committed to open-source projects, actively sharing resources and knowledge to broaden the application of its technologies.

Stelvio Therapeutics is a biopharmaceutical company focused on developing innovative therapies for incurable cancers and neurodegenerative diseases. The company utilizes a machine vision and learning platform to drive diseased stem cells to non-diseased states by identifying drugs that induce epigenetic changes. Its proprietary Microscopic Imaging of Epigenetic Landscapes (MIEL) technology facilitates the discovery of small molecules capable of differentiating or reversing cancerous cells into benign types, potentially offering curative outcomes. Founded in 2017 and headquartered in San Diego, California, Stelvio Therapeutics combines scientific creativity, clinical excellence, and professional management to advance novel drug therapies and precision medicine diagnostics, with a particular emphasis on personalized treatments for conditions such as glioblastoma.

PLANTeDIT Limited is a biotech company headquartered in Cork, Ireland, established in 2017. It specializes in developing plant transformation technology systems that utilize CRISPR/Cas9 RNPs for direct genome editing in a variety of crop species. The company focuses on producing non-transgenic, regulatory-free, and sustainable plant products, such as high oleic soya, aimed at health-conscious consumers. Additionally, PLANTeDIT is engaged in creating mammalian proteins and human pharmaceuticals through its innovative genome-edited plant platform, which allows for the efficient production of cost-effective biopharmaceuticals. The company's commitment to sustainability and consumer-oriented solutions positions it as a leader in the advancement of genome editing technology in agriculture and biomedicine.