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Lura Health develops a non-invasive continuous health monitoring platform that uses saliva as a diagnostic fluid. The company integrates micro-sensors into orthodontic devices such as retainers, aligners, and brackets to continuously measure saliva analytes and securely transmit data to a smartphone app, enabling users to monitor oral health metrics and potentially support broader chronic disease management. Target markets include heart disease, chronic kidney disease, diabetes, and tooth decay. Founded in 2017, the company is based in Cambridge, Massachusetts.

Microbiome-focused therapeutics for diseases of the oral cavity and their systemic effects

Oralta is a United States-based company specializing in the production of probiotic supplements aimed at improving oral health. The company manufactures FRESH BREATH, a line of chewable tablets designed to combat bad breath by targeting odor-producing bacteria. These probiotics work by restoring a healthy balance of beneficial bacteria in the mouth, effectively eliminating the harmful germs responsible for unpleasant odors. In addition to addressing bad breath, Oralta's products also focus on broader oral health issues, such as tooth decay and gum disease. By inactivating the byproducts of these harmful bacteria, Oralta supports sustainable oral hygiene practices, allowing users to maintain their overall dental well-being.

Microbiome-focused therapeutics for diseases of the oral cavity and their systemic effects

Lura Health develops a non-invasive continuous health monitoring platform that uses saliva as a diagnostic fluid. The company integrates micro-sensors into orthodontic devices such as retainers, aligners, and brackets to continuously measure saliva analytes and securely transmit data to a smartphone app, enabling users to monitor oral health metrics and potentially support broader chronic disease management. Target markets include heart disease, chronic kidney disease, diabetes, and tooth decay. Founded in 2017, the company is based in Cambridge, Massachusetts.

Xixilab Limited specializes in orthodontics and teeth brightening products, focusing on enhancing dental care and improving smiles. The company offers a range of products, including a correction kit that features braces, a toothbrush, a mouth opener, a retainer, and wax, as well as a whitening kit containing blue light, brightening pens, a maintenance pen, a restorative pen, a teeth color card, and a user manual. Established in 2017 and headquartered in Hong Kong, Xixilab partners with dental clinics and professionals to provide both customized oral health products and affordable dental beauty services. The company's mission is to inspire confidence through improved smiles, emphasizing the importance of first impressions and the role of a confident smile in projecting a positive image.

Lura Health develops a non-invasive continuous health monitoring platform that uses saliva as a diagnostic fluid. The company integrates micro-sensors into orthodontic devices such as retainers, aligners, and brackets to continuously measure saliva analytes and securely transmit data to a smartphone app, enabling users to monitor oral health metrics and potentially support broader chronic disease management. Target markets include heart disease, chronic kidney disease, diabetes, and tooth decay. Founded in 2017, the company is based in Cambridge, Massachusetts.

Hippo & Crate Limited, established in 2016 and headquartered in Jing'an, China, specializes in the direct-to-consumer (D2C) distribution of high-quality oral care products. The company offers a subscription-based service for toothpaste, toothbrushes, mouthwash, and other complementary items, focusing on design, production, and distribution. Hippo & Crate aims to improve oral hygiene quality while promoting environmental responsibility through its products.

Kolibree develops smart dental care products. Their flagship is an AI-powered electric toothbrush that engages users and offers real-time feedback, aiming to enhance oral hygiene and prevent dental issues.

Kolibree develops smart dental care products. Their flagship is an AI-powered electric toothbrush that engages users and offers real-time feedback, aiming to enhance oral hygiene and prevent dental issues.