Hoofprint Biome
Series A in 2025 
Hoofprint Biome is a biotechnology company that develops probiotics and natural enzymes to enhance the sustainability of ruminant livestock production. Their products improve cattle health and digestive care by reducing methane emissions, thereby enabling the livestock industry to adopt more sustainable practices through microbiome engineering.
InnSight Technology
Seed Round in 2025 
InnSight Technology is a biotechnology company focused on advancing the diagnostics and evaluation of eye diseases. The company specializes in developing innovative ophthalmic devices, including a novel, hand-held biosensor designed for the detection of anterior ophthalmic injuries. Additionally, InnSight Technology works on the development of nanotechnology-based medical devices aimed at addressing various clinical needs in ophthalmology. By providing these advanced tools, the company enables clinicians to enhance ocular care and improve patient outcomes in eye health.
Fermeate
Seed Round in 2025 
Fermeate is a stealth-mode biotechnology company that specializes in photomolecular fermentation technology. This innovative approach aims to enhance sustainability and efficiency within the biomanufacturing industry.
Materia Bioworks
Seed Round in 2025 
Materia Bioworks is a pioneering company that develops data-driven informatics tools to facilitate the creation and adoption of sustainable biomaterials. Their AI-powered platform streamlines the process of developing and manufacturing biomaterial products, from sourcing materials to final production. This enables material scientists, product developers, suppliers, and converters to accelerate and enhance their work in biomaterial applications, fostering a more sustainable future across various industries.
Prellis Biologics
Series C in 2025 
Prellis Biologics is a biotechnology company based in San Francisco, founded in 2016, focused on bioprinting vascularized human tissues and organs for drug development, disease modeling, and transplantation. Its platform enables rapid, high-resolution printing of tissues and organoids, including lymph node models, to reproduce human immune responses. This capability supports antibody discovery, immunogenicity assessment, and tumor–immune studies, aiming to accelerate early-stage drug discovery and translational pharmacology while advancing the development of tissue and organ therapies.
Avalo is a plant biology company that employs interpretable machine learning, genomic discovery, and evolutionary theory to expedite the development of new crops tailored for future agricultural needs. Utilizing AI-assisted plant breeding methods, Avalo creates non-GMO products that foster natural biodiversity. Its core technology, a discovery engine, can swiftly identify genetic bases of complex traits even in understudied crops, reducing time and cost significantly compared to traditional methods. This enables Avalo to forecast and enhance crop traits like drought tolerance and nutrient density, adapting agriculture to changing climates.
Hoofprint Biome
Series A in 2025 
Hoofprint Biome is a biotechnology company that develops probiotics and natural enzymes to enhance the sustainability of ruminant livestock production. Their products improve cattle health and digestive care by reducing methane emissions, thereby enabling the livestock industry to adopt more sustainable practices through microbiome engineering.
Afynia Laboratories
Seed Round in 2025 
Aima Laboratories is a women's health healthcare company that provides innovative solutions to diagnostic and therapeutic difficulties. AIMA is working on the first non-invasive endometriosis diagnostic tool for the market. If you have chronic pelvic/period pain or are having difficulty becoming pregnant, you may have endometriosis.
Oxyle specializes in wastewater treatment, focusing on the removal of hazardous micropollutants such as pesticides, chemicals, pharmaceuticals, and endocrine disruptors. Serving industries like pharmaceuticals, biotech, chemicals, food & beverage, electronics, hospitals, and wastewater plants, Oxyle's innovative technology helps reduce toxic pollutants and carbon emissions while providing regulatory relief to clients.
Particella
Convertible Note in 2025 
Particella is a biotechnology company that specializes in developing a proprietary oral lipid nanoparticle technology designed to deliver mRNA and other nucleic acids. This innovative approach aims to transform the administration of biological medicines by utilizing the intestinal tract to facilitate the secretion of proteins into the bloodstream. By enabling the oral delivery of protein biologics, Particella's technology seeks to address the limitations of current methods, ultimately allowing healthcare providers to prevent gastrointestinal diseases in patients more effectively. The company's advancements hold the potential to create a new category of medicines, enhancing the accessibility and efficacy of treatments.
RyboDyn
Pre Seed Round in 2025 
RyboDyn is a biotechnology research company focused on developing innovative therapeutics aimed at training the immune system to identify and eliminate cancer from within the body. By leveraging cutting-edge scientific breakthroughs, RyboDyn creates advanced treatments that promise significant improvements in the management of terminal diseases and various ailments. The company's commitment to enhancing medicine through its research positions it at the forefront of the fight against cancer, with the potential to transform patient care and outcomes.
Proton Intelligence
Seed Round in 2024 
Proton Intelligence develops a wearable device that monitors potassium levels in real-time via interstitial fluid, closely correlated to blood. This enables clinicians and patients to manage medications and diets effectively for improved heart and kidney care, particularly targeting hyperkalemia in chronic kidney disease patients with co-morbidities.
Ten63 Therapeutics
Series A in 2024 
Ten63 Therapeutics, Inc. is a biotechnology company based in Chapel Hill, North Carolina, focused on developing potent therapeutics for medically validated yet undruggable targets. Founded in 2017, the company utilizes its innovative platform, COPPER, which combines machine learning-based computational chemistry with advanced physical modeling to explore an extensive chemical space. This approach allows Ten63 Therapeutics to discover novel drug candidates for some of the most lethal diseases by employing proprietary algorithms for scaffold redesign and optimizing chemical design. By integrating these technologies, the company aims to produce durable therapies and improve drug resistance prediction, ultimately addressing challenges in drug development for previously intractable targets.
Giraffe Bio
Seed Round in 2024 
Giraffe Bio specializes in developing biomolecular technology to enhance the efficiency and sustainability of critical mineral extraction. Their platform tailors biomolecules to the specific geology of each mine, boosting metal recovery, reducing water usage, and minimizing environmental impact. This is achieved by integrating biology, artificial intelligence, and hardware to optimize extraction processes, enabling clients to improve recovery rates and reduce extraction times.
Benerg is an Internet of Things (IoT) technology company that specializes in developing scalable biogas systems designed to efficiently convert food and bio waste into energy. The company focuses on building biogas machines that operate independently of the grid, and it also produces organic fertilizers as a byproduct. By providing innovative solutions for energy resource management, Benerg enables businesses to reduce waste and contribute to environmental sustainability.
AlkaLi Labs
Convertible Note in 2024 
Founded in 2023, AlkaLi Labs is a biotechnology company based in San Francisco. It specializes in recovering critical minerals like lithium and cobalt from industrial waste streams using bioengineering solutions.
BioSapien
Seed Round in 2024 
BioSapien is a biotechnology company developing innovative, biodegradable implantable devices that deliver pharmaceuticals directly to cancer sites. Its flagship product, MediChip, uses 3D printing technology to create a mesh capable of sustained drug release, reducing systemic side effects and improving patient care.
Unlocked Labs
Seed Round in 2024 
Unlocked Labs develops targeted probiotics designed to manage specific health conditions. Their first product focuses on reducing kidney stone risk by digesting a stone-forming compound found in healthy foods like leafy vegetables.
BioLattice
Seed Round in 2024 
BioLattice is a biotechnology company focused on developing tissue-engineered cornea technology. Their primary goal is to provide a viable alternative to donor tissue for full-thickness corneal transplants. The company's innovative technology offers a corneal prototype with vision-correcting capabilities, aiming to restore sight for patients requiring corneal transplants.
Vitarka Therapeutics
Seed Round in 2024 
Vitarka Therapeutics is a London-based company that specializes in developing medical technologies and solutions aimed at treating various types of cancer. The company has created a targeted non-viral delivery platform designed for intracellular targets, particularly in oncology, neuroscience, and neurodegeneration. This innovative platform works by activating the immune system and normalizing tumor vasculature, significantly improving outcomes for late-stage cancer patients, including those with lung, colon, and breast cancers. By utilizing re-engineered pore-forming proteins, Vitarka Therapeutics enables cell-specific targeting and endosomal release of therapeutic cargo, providing cancer patients with improved prospects for leading normal lives and maintaining hope for the future.
VIAN Therapeutics
Seed Round in 2024 
VIAN Therapeutics is an early-stage biotechnology company focused on transforming retinal disease treatment. Its lead product, a first-in-class non-invasive eyedrop, aims to replace invasive injections for conditions like age-related macular degeneration and diabetic macular edema.
Asterix Foods
Convertible Note in 2024 
Asterix Foods is a biotechnology company based in Tel Aviv, Israel, founded in 2022. The company specializes in developing protein production through plant-cell culture techniques, focusing on the creation of bioactive proteins for food applications. Asterix Foods aims to provide scalable, functional, and complex proteins that are derived from plant cell cultures, offering an animal-free alternative for consumers.
Exosomm
Seed Round in 2024 
Exosomm is an innovative foodtech start-up focused on developing nutritional solutions derived from natural milk exosomes. The company was founded based on research from Hadassah Medical Center, led by Prof. Reif's team. Exosomm's flagship product is a specialized food formula designed for patients suffering from inflammatory bowel diseases, such as Crohn's disease and ulcerative colitis. This product utilizes a patented active anti-inflammatory ingredient sourced from milk exosomes, which are isolated using a natural and environmentally friendly process. By targeting health and immunity, Exosomm aims to provide effective solutions for individuals with specific dietary needs.
Flore by Sun Genomics
Convertible Note in 2024 
Sun Genomics, Inc. is a microbiome health company based in San Diego, California, specializing in customized probiotics aimed at addressing dysbiosis. Founded in 2014, the company’s flagship product, Floré, combines a gut microbiome test with personalized probiotic formulations tailored to individual gut profiles, assessed through whole-genome sequencing. The Floré Gut Test includes a microflora collection kit, a comprehensive microflora profile analysis, and wellness consultations. Additionally, Sun Genomics offers Floré Tots, a probiotic solution designed for children up to age 12, which comes in a convenient powder form that can be easily mixed with beverages. The company sells its products online, providing an automatic renewal service to enhance customer convenience.
Capra Biosciences
Convertible Note in 2024 
Capra Biosciences is a biotechnology company that develops bioreactor technology to enable efficient, low-carbon production of bio-based chemicals. Its biofilm bioreactor platform reduces downstream processing requirements and costs in bio-manufacturing and supports the production of hydrophobic products, including fuels, retinol, and performance lubricants.
OneSkin is a biotechnology company focused on skin aging and longevity that develops testing platforms and consumer products. It uses animal-free three-dimensional human skin models to evaluate the safety and efficacy of cosmetic ingredients and anti-aging compounds, supporting research and validation for the cosmetic and ingredient supplier industries. The company has developed a proprietary peptide, OS-01, intended to reduce skin biological age by decreasing the accumulation of aged cells, improving cellular repair, and strengthening the epidermal barrier. Its consumer offering includes a vegan topical product based on OS-01 designed for all skin types, marketed through its website. The business combines in vitro testing services with product development to address root causes of skin aging and support proper skin cell function.
Synplexity
Seed Round in 2024 
Synplexity is a biotechnology company located in New Castle, Delaware, specializing in mutational scanning and multiplexed gene synthesis through advanced artificial intelligence technology. The company operates a large-scale gene synthesis and proteomics discovery platform that utilizes microdroplets as microreactors. This innovative approach allows for the efficient creation of multiplex gene libraries, which have applications across various sectors, including therapeutics, biomanufacturing, agriculture, and climate systems. Synplexity aims to drive advancements in healthcare and other industries through its cutting-edge genetic technologies.
Laguna Bio
Seed Round in 2024 
Founded in 2022 and headquartered in Berkeley, California, Laguna Bio develops a drug discovery platform designed to selectively activate and expand the innate immune system against cancer. The company focuses on providing a specific type of T cell for the immune system to fight solid tumors by increasing the response rate of bispecific antibody drugs.
FREZENT
Seed Round in 2024 
FREZENT is a biotechnology company focused on developing innovative therapeutics for advanced-stage cancer patients. It specializes in creating biological inhibitors that target cancer-specific lipid metabolism, aiming to prevent the reactivation of dormant cancer cells.
NanoPlume
Seed Round in 2024 
NanoPlume is a biomaterial manufacturer specializing in the large-scale production of innovative, eco-friendly biomaterials, notably Bio-Aerogel. The company focuses on creating advanced insulating biomaterials and aerogels, aiming to enhance energy and space efficiency, as well as promote circularity across various industries. By utilizing organic and recycled feedstocks and green technology, NanoPlume reduces waste and minimizes energy consumption. Its products are designed to insulate cargo boxes in the cold chain healthcare logistics sector, reducing payload and energy consumption, and extending battery range.
Huue
Convertible Note in 2024 
Huue is a company specializing in sustainable dyeing solutions for the fashion and textile industries, particularly focusing on the denim supply chain. It employs innovative biotechnology to produce bio-synthesized dyes through a fermentation process involving naturally occurring microorganisms. This method not only eliminates the need for toxic chemicals traditionally used in dye production but also utilizes renewable resources, making it an eco-friendly alternative. By offering greener options for color production, Huue aims to support the industry's transition towards more sustainable practices, ultimately contributing to a more environmentally responsible approach to fashion.
DisperseBio
Seed Round in 2024 
DisperseBio is a Biotechnology Research firm developing a mechanism to counter microbial contamination on natural surfaces like human body.
Mothership Materials
Seed Round in 2024 
Mothership Materials specializes in converting agricultural waste into valuable biomolecules using its proprietary Targeted Molecular Recovery (TMR) technology. The company's process efficiently extracts proteins, lipids, antioxidants, sugars, and cellulose from waste streams, enabling agricultural producers and waste managers to create a circular economy and maximize waste value.
Minutia
Seed Round in 2024 
Minutia is a biotechnology company focused on developing innovative stem cell-derived transplants aimed at treating Type 1 Diabetes. The company specializes in creating insulin-producing cell transplants that incorporate proprietary nanosensors, allowing for real-time monitoring of transplant status. These immune-evasive cells are designed for subcutaneous implantation, addressing common challenges associated with transplant procedures. By advancing this technology, Minutia seeks to transform the clinical landscape for diabetes management and cell replacement therapies, ultimately working towards a functional cure for this condition.
Sóliome
Seed Round in 2024 
Founded in 2021, Sóliome is a biotechnology company based in San Francisco, California. It specializes in developing protein-based sunscreens that are safe and effective, using molecules naturally produced by the human body to protect against harmful UV rays.
Gatehouse Bio
Convertible Note in 2024 
Gatehouse Bio is a biotech company based in Waltham, Massachusetts, founded in 2016. The company specializes in the development of therapies utilizing a novel bioinformatics platform that focuses on small ribonucleic acid (RNA) biomarkers. This platform is designed to classify patient samples with binary accuracy and identifies disease-associated mutations, enabling the creation of targeted therapeutics. By employing artificial intelligence, Gatehouse Bio aims to analyze small RNA genes and design oligonucleotides that can effectively counteract the effects of these mutations. Their research and development efforts target therapeutic areas with known heterogeneity, such as fibrosis, inflammation, and neurodegeneration, with the goal of unlocking the potential for improved patient outcomes through personalized medicine.
Calyx
Funding Round in 2024 
Calyx develops advanced sensor platforms that monitor various parameters in poultry farming with exceptional specificity and sensitivity. The company combines AI computer vision technology, bio-engineered sensors, and data science to address complex challenges in the poultry industry.
Asta Bio
Seed Round in 2024 
Asta Bio is a biotechnology company specializing in the development of radiotherapeutics for cancer treatment. It focuses on combining the alpha-emitting radioisotope 211-Astatine with multivalent single-domain antibodies to deliver targeted alpha radiation to tumor cells, sparing healthy cells. This approach aims to effectively destroy cancer cells by breaking their DNA strands.
DNAzyme
Pre Seed Round in 2024 
DNAzyme is a biotechnology company specializing in the development of enzymes derived from Antarctic extremophile microorganisms as active ingredients for skin health applications. Utilizing recombinant DNA repair technology, the company produces highly pure enzymes at an industrial scale, enabling clinicians to create innovative solutions for skin health and rejuvenation in both the cosmetic and pharmaceutical industries.
Tinkeso Therapeutics
Seed Round in 2024 
Tinkeso Therapeutics is a biotechnology company specializing in the development of innovative, off-the-shelf cell therapies for treating cancer and autoimmune diseases. The company focuses on creating allogeneic chimeric antigen receptor (CAR) engineered natural killer T (NKT) cell therapies, which use NKT cells to target and destroy cancer cells or modulate the immune response in autoimmune conditions. This approach aims to increase treatment accessibility and scalability by utilizing non-patient-specific cells.
Bugbiome
Seed Round in 2024 
BugBiome is a biotechnology company that develops eco-friendly bio-repellents to create natural pest control products. It focuses on identifying and enhancing beneficial microbes that deter pests organically, providing an alternative to traditional chemical methods. The company aims to minimize environmental impact and promote sustainable pest management practices, potentially benefiting sectors such as agriculture and households.
heXem bio
Seed Round in 2024 
heXem bio specializes in recording solutions for the early development of humans for longevity.
Semion
Convertible Note in 2024 
Restoring crops' ability to defend against pests.
ZiO Health
Convertible Note in 2024 
ZiO Health is a biotechnology company that develops pocket-sized devices featuring proprietary biosensor technology and machine learning algorithms. These devices enable real-time laboratory testing at the point-of-care, enhancing patient care by combining immediate results with individual patient profiles.
Fermeate
Seed Round in 2024 
Fermeate is a stealth-mode biotechnology company that specializes in photomolecular fermentation technology. This innovative approach aims to enhance sustainability and efficiency within the biomanufacturing industry.
CellCo provides next generation biologics and biotherapies by integrating synthetic biology and AI.
Oobli develops healthy, low-calorie protein sweeteners derived from exotic plants. These rare compounds offer great taste without affecting blood sugar levels or gut microbiome. The company has secured regulatory approvals such as FDA 'no questions' letters and GRAS status for multiple proteins.
Afynia Laboratories
Seed Round in 2024 
Aima Laboratories is a women's health healthcare company that provides innovative solutions to diagnostic and therapeutic difficulties. AIMA is working on the first non-invasive endometriosis diagnostic tool for the market. If you have chronic pelvic/period pain or are having difficulty becoming pregnant, you may have endometriosis.
Valanx Biotech
Seed Round in 2024 
VALANX Biotech GmbH is an innovative biotechnology company based in Klosterneuburg, Austria, founded in 2017. The company specializes in the development and manufacturing of synthetic programmable amino acids, notably Norl, and the reactive amino acid SnapIt. These products are designed to facilitate the creation of antibody-drug conjugates, which enhance cancer treatment by selectively targeting cancer cells. VALANX Biotech’s platform also supports PEGylation of therapeutic peptides and proteins, as well as the directed and oriented immobilization of biosensors and biocatalysts. Additionally, the company offers bioanalytics and mass spectrometry services on demand, helping to streamline the development of site-specific protein-drug conjugates in a cost-effective manner.
kegg is a fertility health tracking device from a San Francisco based company founded in 2017 that combines fertility tracking with pelvic floor exercises. The device analyzes changes in cervical fluids to detect the fertile window and ovulation up to seven days in advance, providing users with information to guide conception decisions. By collecting data from cervical fluids, it aims to support women’s health through improved diagnosis, monitoring, and planning related to fertility.
CellCrine
Seed Round in 2024 
CellCrine focuses on discovering enzymes that transform cell culture for the cell-based meats industry.
CellCrine was founded in 2021and was headquartered in United, States.
Transition Biomining
Seed Round in 2024 
Transition Biomining is a technology-focused company specializing in copper ore mining. It employs data-driven methods to enhance copper extraction and mining efficiency. The company's core innovation lies in optimizing microbial communities for heap-leaching operations, aiming to boost metal recovery rates, expedite extraction, and minimize environmental impact. By harnessing the power of microbiomes, Transition Biomining provides sustainable and data-driven solutions to improve clients' extraction processes in both new and existing heap-leaching operations.
MycoWorks
Series D in 2024 
MycoWorks is a biotechnology company specializing in the production of non-plastic and non-animal materials. Utilizing fungal mycelium, they create energy-efficient and biodegradable alternatives to plastic foams, textiles, woods, and leather for various industries such as aerospace, automotive, apparel, and architecture.
VIAN Therapeutics
Seed Round in 2024 
VIAN Therapeutics is an early-stage biotechnology company focused on transforming retinal disease treatment. Its lead product, a first-in-class non-invasive eyedrop, aims to replace invasive injections for conditions like age-related macular degeneration and diabetic macular edema.
OncoPrecision
Convertible Note in 2024 
OncoPrecision develops a patient micro avatar platform that uses single-cell high-throughput biology and machine learning to provide comprehensive patient-derived phenotypic biomarkers. This enables oncologists to tailor cancer therapy across modalities, improving patient success through data-driven decisions based on patient-derived samples.
Prolific Machines
Series B in 2024 
Founded in 2020, Prolific Machines is a San Francisco-based biotech company dedicated to revolutionizing cell production for a sustainable future. It combines advanced technologies to enable large-scale cell manufacturing, aiming to improve therapeutic protein production for biotechnology and pharmaceutical companies.
VisusNano
Seed Round in 2024 
VisusNano Ltd. is a London-based company founded in 2016 that specializes in the development of a drug-eluting intraocular lens implant designed for use in cataract surgery. This innovative technology aims to enhance patient outcomes by reducing the risks associated with the procedure, such as intraocular inflammation, infection, and opacification. By eliminating the need for postoperative eye drops and minimizing the necessity for laser treatments, VisusNano's product has the potential to transform cataract surgery for both human and veterinary patients. The company is currently in the pre-clinical stage of its development.
Bugbiome
Seed Round in 2024 
BugBiome is a biotechnology company that develops eco-friendly bio-repellents to create natural pest control products. It focuses on identifying and enhancing beneficial microbes that deter pests organically, providing an alternative to traditional chemical methods. The company aims to minimize environmental impact and promote sustainable pest management practices, potentially benefiting sectors such as agriculture and households.
Avalo is a plant biology company that employs interpretable machine learning, genomic discovery, and evolutionary theory to expedite the development of new crops tailored for future agricultural needs. Utilizing AI-assisted plant breeding methods, Avalo creates non-GMO products that foster natural biodiversity. Its core technology, a discovery engine, can swiftly identify genetic bases of complex traits even in understudied crops, reducing time and cost significantly compared to traditional methods. This enables Avalo to forecast and enhance crop traits like drought tolerance and nutrient density, adapting agriculture to changing climates.
Founded in 2018, Sundew is a biotechnology company based in Copenhagen. It specializes in providing biological services for treating aquatic pests and diseases using precision fermentation.
Helex
Convertible Note in 2024 
Helex is a biotechnology company developing genomic medicines for kidney-related diseases. It leverages its own genomics data, bioinformatics, and an intelligent data-driven platform to design, verify, and deliver therapy-specific gRNAs, with a focus on non-viral targeted delivery and genome editing for renal indications. The company's platform uses data-driven deep-learning models and high-throughput sequencing data from CRISPR edits in human cell lines to generate reliable predictions and validate them in-house. By combining these capabilities, Helex aims to accelerate CRISPR-based drug research and the development of cell and gene therapies for kidney conditions, offering precise and scalable renal therapeutics.
Calder Biosciences
Seed Round in 2024 
Calder Biosciences engineers next-generation vaccines using its proprietary 3D-Vaxlock technology. This platform generates molecular staples that lock vaccines into their most potent shape, enhancing immune response and stability. Calder's initial focus is on developing a universal flu vaccine and an RSV vaccine for the elderly. Their vaccines aim to protect against life-threatening diseases with improved safety, efficacy, and durability, reducing healthcare burden globally.
CroBio is an agricultural biotechnology company developing a sustainable solution for managing global agricultural drought. It uses genetically engineered root-associated bacteria to produce biomaterials that retain water in the soil, enhancing crop resilience and reducing irrigation requirements.
Cell BioEngines
Pre Seed Round in 2024 
Cell BioEngines is a clinical-stage biotechnology company specializing in developing 'off-the-shelf' stem cell therapies as drugs for treating human diseases. The company's core platform enables the production of high-quality, pure, and potent cell products at scale using a universal blood stem cell-derived technology.
ClimateCrop
Seed Round in 2024 
ClimateCrop develops gene editing and related plant technologies to enable crops to store more carbon and energy, with the goal of increasing yields in biomass and fruit. The approach also enhances crop resilience to extreme weather, supporting climate adaptation and more reliable production for agricultural companies. Founded in 2021 and based in Ness Ziona, the company focuses on leveraging plant energy capture to boost productivity.
Finless Foods
Convertible Note in 2024 
Finless Foods is a biotechnology company that uses cellular agriculture to develop cell-cultured seafood products as sustainable alternatives for human consumption. It grows marine-animal cells to create seafood substitutes, including bluefin tuna, with the goal of offering responsibly produced options that support ocean health and reduce overfishing. Founded in 2017 and based in Emeryville, California, the company concentrates on expanding dietary choices while addressing environmental impacts of traditional seafood.
Bloomlabs
Convertible Note in 2024 
Bloomlabs provides a method to catalyze waste value by regenerating it as adaptable and appealing bio-plastics and textile fibers. It envisions a future in which outmoded, resource-intensive processes are phased out in favor of cutting-edge, sustainable, and scalable alternatives.
Cayuga Biotech
Convertible Note in 2024 
Cayuga Biotech is a biotechnology company developing innovative hemostatic drugs and devices aimed at reducing uncontrollable bleeding, a leading cause of death from traumatic injuries. Its polyphosphate-based drug accelerates the body's natural clotting process to contain bleeding at the injury site, minimizing potential side effects. Cayuga focuses on treating traumatic hemorrhage and rare bleeding disorders.
California Cultured
Series A in 2024 
California Cultured is a food company that uses cellular agriculture to produce cocoa and coffee, with the aim of delivering sustainable, lab-grown ingredients. Its cocoa is described as less bitter and requiring less sugar to achieve flavor, enabling premium quality products with a smaller environmental footprint. The company seeks to address social and environmental concerns linked to traditional cocoa production by avoiding practices such as slavery, deforestation, and child labor. California Cultured was founded in 2020 and is based in Davis, California.
Level Zero
Seed Round in 2024 
Level Zero Health is a technology company specializing in advanced biosensor solutions. It develops wearable devices equipped with DNA-based sensors, designed to precisely monitor key endocrine biomarkers in real-time. By combining biochemistry and nanotechnology, the company collects novel data, empowering users to gain insights into their hormonal health.
Cauldron Ferm
Series A in 2024 
Cauldron Ferm is a bio-acceleration process that exponentially scales up any precision fermented prototype to commercial quantities faster and with a lower cost of goods than any traditional production method.
DropGenie
Convertible Note in 2024 
Founded in Montreal, Canada in 2018, DropGenie is a biotechnology company specializing in automated genetic engineering. It offers a platform that uses microfluidics technology to miniaturize and automate complex synthetic biology workflows, enabling scientists to make changes to genomes efficiently while reducing costs and improving standardization and reproducibility.
Avisa Myko
Convertible Note in 2024 
Avisa Myko is a biotechnology company based in San Francisco, California. It specializes in the production of melanin, a natural pigment with applications in cosmetics, biomedicine, organic semiconductors, biosensors, and latex products. The company's patented technology enables large-scale production of soluble, affordable melanin, offering protection against ionizing radiation and contributing to better health and environmental sustainability.
Reactosome
Seed Round in 2024 
Reactosome is a biotechnology company that develops synthetic nuclei for gene therapy. Its core product, a synthetic nucleus, operates continuously within cells, mimicking the natural nucleus to affect multiple genes simultaneously. This approach aims to enhance the safety and longevity of gene expression, thereby enabling the development of treatments for complex diseases such as cancer and age-related disorders.
Founded in 2013, ZymoChem develops eco-friendly chemical production processes using engineered microbes. These processes convert renewable feedstocks like sugars into industrial chemicals, minimizing carbon loss and enabling cost-competitive bio-based manufacturing.
Feel Therapeutics
Venture Round in 2024 
Feel Therapeutics is a digital health company specializing in precision medicine for mental health. It develops physiological and digital biomarkers using advanced computer science methods, leveraging wearable devices to collect and analyze biometric data.
Chronus Health
Convertible Note in 2024 
Chronus Health develops a portable diagnostic device for delivering point-of-care lab results in minutes. Its device enables real-time diagnosis at the point-of-care, improving time to care and patient outcomes.
Aequor is a biotechnology company focused on the development and commercialization of proprietary chemicals, cleaners, and water treatments designed to address biofilm-related challenges in various industries. Founded by a marine and medical microbiologist, Aequor's innovative products effectively remove and prevent biofilm, which contributes to issues such as microfouling and macrofouling. The company has achieved regulatory approval for numerous non-toxic dispersants and cleaners, classified as environmentally friendly and safe for food contact. Aequor offers a comprehensive range of services, including microbial testing, consulting, and custom product development, and collaborates with complementary service providers to deliver integrated solutions. Notably, Aequor's flagship product has gained recognition for its success in NASA’s water recycling systems on the International Space Station and has demonstrated utility in various applications, from cooling towers to groundwater remediation. As a Woman-Owned Small Business, Aequor is positioned to leverage government opportunities and anticipates significant returns on investment as it expands its sales efforts across multiple sectors.
Flore by Sun Genomics
Series B in 2023 
Sun Genomics, Inc. is a microbiome health company based in San Diego, California, specializing in customized probiotics aimed at addressing dysbiosis. Founded in 2014, the company’s flagship product, Floré, combines a gut microbiome test with personalized probiotic formulations tailored to individual gut profiles, assessed through whole-genome sequencing. The Floré Gut Test includes a microflora collection kit, a comprehensive microflora profile analysis, and wellness consultations. Additionally, Sun Genomics offers Floré Tots, a probiotic solution designed for children up to age 12, which comes in a convenient powder form that can be easily mixed with beverages. The company sells its products online, providing an automatic renewal service to enhance customer convenience.
Lura Health
Seed Round in 2023 
Lura Health develops a non-invasive continuous health monitoring platform that uses saliva as a diagnostic fluid. The company integrates micro-sensors into orthodontic devices such as retainers, aligners, and brackets to continuously measure saliva analytes and securely transmit data to a smartphone app, enabling users to monitor oral health metrics and potentially support broader chronic disease management. Target markets include heart disease, chronic kidney disease, diabetes, and tooth decay. Founded in 2017, the company is based in Cambridge, Massachusetts.
Unlocked Labs
Seed Round in 2023 
Unlocked Labs develops targeted probiotics designed to manage specific health conditions. Their first product focuses on reducing kidney stone risk by digesting a stone-forming compound found in healthy foods like leafy vegetables.
RyboDyn
Seed Round in 2023 
RyboDyn is a biotechnology research company focused on developing innovative therapeutics aimed at training the immune system to identify and eliminate cancer from within the body. By leveraging cutting-edge scientific breakthroughs, RyboDyn creates advanced treatments that promise significant improvements in the management of terminal diseases and various ailments. The company's commitment to enhancing medicine through its research positions it at the forefront of the fight against cancer, with the potential to transform patient care and outcomes.
Atlantic Fish Company
Pre Seed Round in 2023 
Atlantic Fish Company is focused on producing cultivated seafood through cellular agriculture, operating from its headquarters in Raleigh-Durham, North Carolina. The company aims to provide sustainable seafood options by cultivating fish in a controlled environment. This innovative approach allows Atlantic Fish Company to offer fresh fish meat that maintains the natural taste while minimizing the environmental impact associated with traditional fishing practices. By leveraging cellular agriculture, the company seeks to meet the growing demand for sustainable protein sources.
Prellis Biologics
Series C in 2023 
Prellis Biologics is a biotechnology company based in San Francisco, founded in 2016, focused on bioprinting vascularized human tissues and organs for drug development, disease modeling, and transplantation. Its platform enables rapid, high-resolution printing of tissues and organoids, including lymph node models, to reproduce human immune responses. This capability supports antibody discovery, immunogenicity assessment, and tumor–immune studies, aiming to accelerate early-stage drug discovery and translational pharmacology while advancing the development of tissue and organ therapies.
TômTex specializes in recycling agricultural waste, primarily focusing on seafood shells, mushrooms, and coffee grounds. The company transforms these materials into sustainable, practical alternatives to conventional commercial materials, aiming to minimize environmental impact.
Hypercell Technologies
Seed Round in 2023 
Hypercell Technologies develops tools to control infectious diseases in animals, including diagnostics and monoclonal antibodies designed to curb viruses in production animal reservoirs. The company employs molecular biology to create rapid, on-farm diagnostics that enable veterinarians to detect infections quickly and implement preventive measures. By focusing on proactive control of viruses in animal populations, Hypercell aims to reduce the emergence of diseases that could threaten human health and improve animal health management across production settings.
Valanx Biotech
Seed Round in 2023 
VALANX Biotech GmbH is an innovative biotechnology company based in Klosterneuburg, Austria, founded in 2017. The company specializes in the development and manufacturing of synthetic programmable amino acids, notably Norl, and the reactive amino acid SnapIt. These products are designed to facilitate the creation of antibody-drug conjugates, which enhance cancer treatment by selectively targeting cancer cells. VALANX Biotech’s platform also supports PEGylation of therapeutic peptides and proteins, as well as the directed and oriented immobilization of biosensors and biocatalysts. Additionally, the company offers bioanalytics and mass spectrometry services on demand, helping to streamline the development of site-specific protein-drug conjugates in a cost-effective manner.
Lillianah Technologies
Seed Round in 2023 
Lillianah Technologies is a company dedicated to developing innovative carbon capture technology aimed at restoring marine ecosystems affected by pollution and other environmental challenges. Comprising a team of scientists, Lillianah focuses on optimizing the biological pump in oceans, which is crucial for maintaining ecological balance. By harnessing the ocean's potential, the company seeks to address the detrimental impacts of human activity, such as fertilizer runoff, and contribute to reversing environmental degradation. Through its efforts, Lillianah Technologies aspires to create sustainable solutions that benefit both the oceans and the broader environment.
Gozen operates a material science platform focused on creating biomaterials for sustainability. It uses microorganisms and organic waste to develop fully biodegradable, biocompatible, and non-toxic alternatives to leather, aiming to provide sustainable options for the fashion industry.
Biofluff
Seed Round in 2023 
BioFluff is a manufacturer specializing in plant-based fur designed to serve the fashion industry by providing a sustainable alternative to animal and plastic fur. The company utilizes a patented process along with retrofitted equipment to ensure a scalable production of its eco-friendly materials. Sourced from organic renewable fiber plants, BioFluff’s products are developed without gene splicing, gene editing, or the use of petrochemicals and unsustainable raw-oil derivatives. This commitment to sustainability extends to its customization services, allowing clients to personalize their materials according to specific features such as fur length, fiber density, color, top fur strength, bottom fur insulation properties, and suppleness. By combining innovation with customization options, BioFluff aims to meet the growing demand for luxury, sustainable textiles within the fashion industry.
Pyrone Systems
Seed Round in 2023 
Founded in 2021, Pyrone Systems specializes in developing biopesticides that combine biological and chemical approaches. The company aims to create safe, effective, and sustainable products by utilizing scalable biology-based methodologies.
FREZENT
Seed Round in 2023 
FREZENT is a biotechnology company focused on developing innovative therapeutics for advanced-stage cancer patients. It specializes in creating biological inhibitors that target cancer-specific lipid metabolism, aiming to prevent the reactivation of dormant cancer cells.
BioAesthetics
Convertible Note in 2023 
BioAesthetics develops tissue-engineered nipple-areolar complex grafts to support breast reconstruction after mastectomy. The graft is designed as a scaffold for the patient's own cells to populate and regenerate the nipple and areola during reconstruction, aiming to improve cosmetic and reconstructive outcomes. The company originated as a Tulane University spin-out and was founded in 2015.
Gatehouse Bio
Convertible Note in 2023 
Gatehouse Bio is a biotech company based in Waltham, Massachusetts, founded in 2016. The company specializes in the development of therapies utilizing a novel bioinformatics platform that focuses on small ribonucleic acid (RNA) biomarkers. This platform is designed to classify patient samples with binary accuracy and identifies disease-associated mutations, enabling the creation of targeted therapeutics. By employing artificial intelligence, Gatehouse Bio aims to analyze small RNA genes and design oligonucleotides that can effectively counteract the effects of these mutations. Their research and development efforts target therapeutic areas with known heterogeneity, such as fibrosis, inflammation, and neurodegeneration, with the goal of unlocking the potential for improved patient outcomes through personalized medicine.
Diptera.ai
Convertible Note in 2023 
Diptera.ai develops mosquito control technology that uses the sterile insect technique to reduce mosquito populations. It offers a ready-to-use module that releases sterile male mosquitoes over a period of weeks, enabling ongoing suppression without on-site rearing or sorting facilities. The system combines advanced optics, computer vision, and artificial intelligence to prepare and deploy sterile insects, allowing municipal authorities to conduct large-scale vector control more affordably and efficiently. Based in Jerusalem, Israel, the company aims to make sterile insect technique accessible for urban pest management by eliminating the need for traditional rearing infrastructure and simplifying deployment. The solution is designed to be integrated into existing public health programs to curb disease-carrying mosquitoes while reducing operational complexity.
Calder Biosciences
Seed Round in 2023 
Calder Biosciences engineers next-generation vaccines using its proprietary 3D-Vaxlock technology. This platform generates molecular staples that lock vaccines into their most potent shape, enhancing immune response and stability. Calder's initial focus is on developing a universal flu vaccine and an RSV vaccine for the elderly. Their vaccines aim to protect against life-threatening diseases with improved safety, efficacy, and durability, reducing healthcare burden globally.
BryoSphere
Seed Round in 2023 
BryoSphere is a company specializing in the manufacturing of specialty chemicals, employing moss plants and biotechnology methods in the production of their goods. The company is currently focused on the development of two key products: one for addressing skin hyperpigmentation in topical treatments, and another as an anti-cancer drug.
Xias Bio
Seed Round in 2023 
Xias Bio is a biotechnology company focused on producing recombinant proteins. It specializes in creating advanced soluble ingredients with improved attributes such as enhanced gel and film formation, and antioxidant properties. The company's core expertise lies in developing non-immunogenic natural motifs to deliver functionalities for research, beauty, and healthcare applications.
Veloz Bio
Seed Round in 2023 
Veloz Bio is a biotechnology company founded in 2021 and based in Monterrey, Nuevo León. The company specializes in molecular farming to develop and manufacture animal-free and alternative proteins. Utilizing a rapid protein production system, Veloz Bio leverages efficient plant metabolism to create sustainable and affordable protein solutions. This innovative approach enables the company to support biotechnology firms by providing expertise in key areas such as protein production, supercritical fluid extraction, and membrane purification. Through its focus on scalable protein development, Veloz Bio aims to contribute to the advancement of alternative protein sources in the food industry.
QuantumCyte
Series A in 2023 
Founded in 2014, QuantumCyte develops an automated tissue dissection system that uses digital maps to isolate regions of interest containing informative biomarkers. This platform aims to improve cancer outcomes by enabling precise cellular data analysis for predicting drug efficacy.