Silicon Valley Bank

Oak Street Health is a primary care center for adults on Medicare in medically-underserved communities where there is little to no quality healthcare. Its care is based on an entirely new model that is based on value for its patients, not on the volume of services. IT was founded in 2012 and headquartered in Chicago, Illinois.

ViewRay, Inc. is a company that designs, manufactures, and markets advanced radiation therapy systems for cancer treatment. Its primary product, MRIdian, is an MRI-guided radiation therapy system that allows for simultaneous imaging and treatment of cancer patients. This innovative system integrates MRI technology, radiation delivery, and proprietary software to accurately locate and track soft-tissue tumors, enabling precise targeting while minimizing radiation exposure to surrounding healthy tissues. By providing real-time imaging during treatment, MRIdian addresses significant limitations of traditional radiation therapy methods, enhancing the safety and effectiveness of cancer treatment. ViewRay serves a diverse clientele, including university hospitals, community hospitals, private practices, government institutions, and independent cancer centers, primarily in the United States and internationally. The company was founded in 2004 and is headquartered in Oakwood, Ohio.

MetaCX, Inc. specializes in customer lifecycle management software tailored for software-as-a-service (SaaS) and digital product companies. Established in 2018 and headquartered in Indianapolis, Indiana, the company provides an application that enables sellers to manage client relationships effectively while allowing customers to track their usage patterns and outcomes. MetaCX aims to transform the selling, delivering, renewing, and expanding processes by creating a unified digital experience that involves the customer at every stage. By facilitating shared spaces for suppliers and buyers to define and measure outcomes, MetaCX fosters alignment among sales, success, and delivery teams, focusing on the tangible business impact visible to customers.

Standard Bariatrics is a medical device company based in Cincinnati, Ohio, founded in 2014. The company specializes in developing surgical instruments designed specifically for weight-loss surgeries, particularly laparoscopic sleeve gastrectomy. One of its key products, the Standard Clamp, enables surgeons to standardize their techniques, thereby reducing variation and improving efficiency during procedures. The company’s tools are intended to be used alongside general-use endoscopic staplers with reloadable cartridges, which helps to minimize the number of cartridges required for each surgery. This innovation not only lowers costs for healthcare providers but also assists in creating consistent surgical outcomes.

Civis Analytics, Inc. is a data science software company that empowers organizations to make data-driven decisions. Founded in 2013 and based in Chicago, Illinois, Civis offers a range of tools designed to enhance data analysis and audience engagement. Its Civis platform provides predictive analytics capabilities, facilitating end-to-end data science workflows. Key offerings include the Community Outreach and Engagement Hub, which assists government and nonprofit teams in effectively reaching and influencing their target audiences, and the Census Intelligence Center, a resource for supporting census efforts. Additionally, the company features tools such as the Audience Center for customer targeting, Creative Focus for message testing, and Civis Media Optimizer for optimizing TV advertising strategies. Civis Analytics also delivers consumer insights, market research, and data science consulting services, helping clients leverage data to gain a competitive edge in their operations.

Breeze is an InsurTech providing an online platform for consumers to quote and apply for income protection products, like disability insurance & critical illness insurance. Breeze has built insurance technology that makes it easier to apply and underwrite income protection policies from insurance carriers that offer protection in the event of cancer, heart attacks, strokes, and other medical conditions that can lead to a loss of income and cause financial trauma. Leveraging industry expertise and innovative technology, Breeze's remote-friendly team is building a better way to buy insurance for life’s most financially vulnerable moments. Breeze was founded in 2019 by Colin Nabity & Cody Leach and is based out of Omaha, Nebraska.

Path Robotics, Inc., based in Cleveland, Ohio, specializes in the manufacture of autonomous welding robots. Founded in 2018, the company focuses on designing robotic welding systems that utilize artificial intelligence and machine learning to enhance precision and adaptability in manufacturing processes. These advanced systems automate repetitive welding tasks, helping manufacturers boost productivity while reducing initial costs. By addressing workforce challenges in the manufacturing sector, Path Robotics offers effective automation solutions that streamline operations. Their robots are engineered to autonomously locate and weld seams, significantly reducing production time and improving quality by minimizing errors and inconsistencies. This technology enables industries to simplify their production processes and enhance overall efficiency.

LogicGate, Inc. specializes in enterprise process automation solutions, providing a platform that allows users to create applications through an intuitive drag-and-drop interface. The platform, known as Risk Cloud, is designed to facilitate various risk management activities, including regulatory change management, enterprise risk management, incident management, and compliance management across multiple industries such as finance, healthcare, and energy. By enhancing operational controls and enabling collaboration on risk management, LogicGate's technology empowers organizations to adapt to changing business conditions and streamline their compliance processes. Founded in 2015 and based in Chicago, Illinois, the company aims to centralize and automate risk-related activities, allowing businesses to manage risks effectively without relying heavily on external consultants.

CoolerX is a company that develops interactive digital displays designed to replace traditional glass doors in retail store aisles. Founded in Chicago in 2017, CoolerX's platform enhances the shopping experience by providing consumers with easy access to information, helping them make informed decisions based on their budgets, tastes, and health preferences. By integrating IoT technology into cooler and freezer surfaces, CoolerX enables retailers to improve sales through personalized advertising and smart merchandising. Additionally, the platform offers consumer product companies a new avenue for brand awareness and product visibility at the point-of-sale, supported by real-time analytics.

FireMon is an enterprise security management company that allows its users to continuously analyze, visualize, and improve their existing network security infrastructure and firewall management. It helps organizations find, correct, and avoid gaps in their existing network security infrastructure. FireMon’s proactive security intelligence platform provides security decision makers with key management and operations data to reduce risk and offers appropriate levels of access. Its security manager provides the framework for making intelligent, informed decisions to implement security countermeasures in real time. Founded in 2004 by Gary Fish, FireMon is headquartered in Overland Park, Kansas.

The Mom Project, Inc. is a digital marketplace that connects women, particularly mothers, with flexible employment opportunities across various sectors, including marketing, finance, technology, and project management. Established in 2015 and based in Cincinnati, Ohio, the platform serves a community of over 500,000 moms, dads, and allies, facilitating access to job openings at both Fortune 500 companies and small businesses. In addition to matching jobseekers with suitable roles, The Mom Project provides companies with insights into their workplace policies regarding women and offers recommendations to improve conditions for mothers and their employees. By promoting a more supportive work environment, The Mom Project aims to redefine career structures for women and enhance their professional potential while balancing personal goals.

Upgrade, Inc. is an online lending platform based in San Francisco, California, with additional offices in Phoenix, Montreal, and Chicago. Founded in 2016, Upgrade provides access to personal loans and the Upgrade Card, offering consumers affordable credit options. The Upgrade Card combines the benefits of traditional credit cards with the responsible lending characteristics of installment loans, available at numerous retail locations in the U.S. In addition to lending services, Upgrade offers free credit monitoring, alerts, and educational tools designed to help consumers understand and manage their finances effectively. By combining financial products with educational resources, Upgrade aims to promote responsible credit use among mainstream consumers.

LogicGate, Inc. specializes in enterprise process automation solutions, providing a platform that allows users to create applications through an intuitive drag-and-drop interface. The platform, known as Risk Cloud, is designed to facilitate various risk management activities, including regulatory change management, enterprise risk management, incident management, and compliance management across multiple industries such as finance, healthcare, and energy. By enhancing operational controls and enabling collaboration on risk management, LogicGate's technology empowers organizations to adapt to changing business conditions and streamline their compliance processes. Founded in 2015 and based in Chicago, Illinois, the company aims to centralize and automate risk-related activities, allowing businesses to manage risks effectively without relying heavily on external consultants.

Phathom Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company based in Buffalo Grove, Illinois, focused on developing and commercializing innovative treatments for gastrointestinal diseases. Established in 2018 and launched in 2019, the company is advancing its lead drug candidate, vonoprazan, a potassium-competitive acid blocker (P-CAB) that effectively inhibits acid secretion in the stomach. Vonoprazan is currently undergoing Phase III clinical trials for the treatment of erosive gastroesophageal reflux disease and is also being studied in combination with antibiotics for the treatment of Helicobacter pylori infection. The company aims to address significant unmet medical needs in patients suffering from acid-related disorders and has assembled a team of experts in the gastrointestinal and pharmaceutical fields to drive its development efforts.

Hireology is a staffing and hiring platform for the franchise and retail-automotive industries. It was founded on a simple but powerful concept which is by analyzing the behaviors of top-performing employees, organizations can create highly accurate systems for identifying the best candidate for the job. Through its Selection Manager platform, Hireology helps decentralized organizations across all industries transform their talent acquisition, leading to better hiring decisions, lower turnover, and increased productivity and profitability at each location. It was founded in 2010 and is headquartered in Chicago.

Clearcover, Inc. is a digital car insurance provider based in Chicago, Illinois, established in 2016. The company focuses on delivering affordable car insurance products through an online platform and agents, utilizing an API-first approach to enhance customer experience. Clearcover leverages advanced technology to streamline the insurance process, minimizing costs by avoiding expensive advertising, which allows them to offer better coverage at lower rates. The company's commitment to innovation and customer satisfaction has garnered recognition, including accolades from Glassdoor and Inc. Magazine for its workplace culture.

Upgrade, Inc. is an online lending platform based in San Francisco, California, with additional offices in Phoenix, Montreal, and Chicago. Founded in 2016, Upgrade provides access to personal loans and the Upgrade Card, offering consumers affordable credit options. The Upgrade Card combines the benefits of traditional credit cards with the responsible lending characteristics of installment loans, available at numerous retail locations in the U.S. In addition to lending services, Upgrade offers free credit monitoring, alerts, and educational tools designed to help consumers understand and manage their finances effectively. By combining financial products with educational resources, Upgrade aims to promote responsible credit use among mainstream consumers.

Root Insurance Company is a property-casualty insurtech based in Columbus, Ohio, that specializes in car insurance and renters insurance. Founded in 1998 and rebranded in 2016, Root leverages smartphone technology to analyze driving behavior, such as braking patterns and speed, to identify safe drivers. This innovative approach allows the company to offer personalized and affordable car insurance rates by insuring only those deemed safe drivers. In addition to car insurance, Root provides app-based renters insurance that is straightforward and tailored to meet consumer needs. Root operates as a subsidiary of its parent company, Root, Inc., which aims to transform the traditional insurance industry through technology-driven solutions.

Clearcover, Inc. is a digital car insurance provider based in Chicago, Illinois, established in 2016. The company focuses on delivering affordable car insurance products through an online platform and agents, utilizing an API-first approach to enhance customer experience. Clearcover leverages advanced technology to streamline the insurance process, minimizing costs by avoiding expensive advertising, which allows them to offer better coverage at lower rates. The company's commitment to innovation and customer satisfaction has garnered recognition, including accolades from Glassdoor and Inc. Magazine for its workplace culture.

Endotronix is a developer of hemodynamic monitoring technologies to help detect worsening heart failure earlier than ever before. The company's platform includes a cloud-based disease management data system and outpatient hemodynamic management with a breakthrough implantable wireless pulmonary artery sensor for early detection of worsening heart failure. It was founded in 2007 and is based in Lisle, Illinois.

aTyr Pharma is a biotherapeutics company based in San Diego, California, specializing in the discovery and development of innovative medicines utilizing novel immunological pathways. The company focuses primarily on ATYR1923, a clinical-stage fusion protein designed to down-regulate immune engagement in interstitial lung diseases by binding to the neuropilin-2 receptor. This candidate is currently undergoing Phase 1b/2a clinical trials. aTyr Pharma has established a strong intellectual property portfolio centered around Physiocrine-based compositions and therapeutic applications, particularly in immunomodulation disorders related to inflammation and immunity. Additionally, the company has formed collaborations with several institutions, including the University of Nebraska Medical Center, CSL Behring, Boston Children’s Hospital, and the Medical University of South Carolina, to advance its research and development efforts. Founded in 2005 by a prominent scientist from The Scripps Research Institute, aTyr is supported by leading life sciences investors.

StreamLink Software-is a Software-as-a-Service company that develops grant management software for nonprofits and the public sector. Ther grants management solution, AmpliFund, is designed for managing every stage of the grant lifecycle and is at the forefront of automating grant compliance and data standardization in the public sector. It was founded in 2008 and is headquartered in Cleveland, Ohio.

Trove is a leading company in the branded resale and trade-in industry, primarily based in Ann Arbor, Michigan. The company provides a sophisticated platform that enables brands to efficiently launch, manage, and scale their resale programs, capturing over 75% of the U.S. branded resale market. Trove's platform offers advanced tools for in-store and digital trade-ins, returns processing, and inventory management, which empower brands to connect with diverse customer demographics and optimize their resale strategies through comprehensive analytics. Trove collaborates with notable brands, including Canada Goose, Michael Kors, and Patagonia, enhancing their ability to manage non-new inventory and enabling peer-to-peer sales. As a Certified B Corporation, Trove emphasizes sustainability in retail, aiming to combine commerce with environmental responsibility and drive the industry toward a more sustainable future.

Project44, Inc. is a cloud-based visibility platform that enhances supply chain management for shippers and third-party logistics companies. Established in 2014 and headquartered in Chicago, Illinois, with additional offices in cities such as Paris, Amsterdam, and Shanghai, the company offers a suite of solutions that includes pricing, routing, scheduling, tracking, and analytics. Project44's platform manages over 1 billion unique shipments annually for more than 1,300 leading brands across various industries, including manufacturing, automotive, and retail. By connecting and automating key transportation processes, Project44 provides real-time visibility and insights, enabling shippers and carriers to improve predictability, resilience, and sustainability in their operations. Recognized as a market leader, Project44 has received numerous accolades, including being named a leader in the Gartner Magic Quadrant and achieving high customer satisfaction rankings.

Signal is the leading SaaS provider of data onboarding and real-time identity resolution. The Signal Open Data Platform helps marketers collect data from any offline or online source, synchronize the data across all touchpoints, and distribute it to any marketing or analytics endpoint – all in real-time. Signal’s technology platform empowers people-based marketers to enhance their customer experience by providing relevance across all channels. Signal was founded in 2009 and is headquartered in Chicago, Illinois, United States.

Olive deploys the AI workforce built specifically for healthcare, delivering hospitals and health systems increased revenue, reduced costs, and increased capacity. Olive automates repetitive, high-volume tasks and workflows, monitoring their performance, identifying improvements, and finding opportunities for new work. Olive gives power back to providers through her ever-growing, unparalleled intelligence made up of shared memories, collective wisdom, and global awareness, learning like a network so hospitals never have to solve the same problem twice. Olive was founded in 2012 and is headquartered in Columbus, Ohio.

Tectonic is a leading technology and business services company serving mid-sized business to enterprise customers with a focus on insight2action automation in the cloud. Headquartered in Denver, with offices in Chicago, Houston and Los Angeles, the company prides itself on working with innovators in informed customer interaction.

Ahalogy, now part of Quotient, operates as a digital marketing platform focused on connecting brands with consumers through their interests. It provides services that include category trend data, authentic influencer content, and social optimization technology. This enables brands and agencies to enhance user engagement and drive sales by leveraging proven return on investment strategies. Ahalogy is recognized as an official Pinterest Marketing Partner and collaborates with other major social networks to optimize marketing efforts. Headquartered in Cincinnati, Ohio, Ahalogy also maintains offices in New York, Chicago, Los Angeles, and San Francisco, positioning itself in key markets for brand marketing.

Zyga Technology, Inc. is a medical device company focused on developing and commercializing minimally invasive products for underserved conditions of the lumbar spine. The company offers the SImmetry Sacroiliac Joint Fusion System, which provides a surgical solution for sacroiliac joint fusion, addressing issues such as joint disruptions and degenerative sacroiliitis. Additionally, Zyga is working on the Glyder Facet Restoration System, an investigational device aimed at treating chronic facetogenic pain. Founded in 2008 and based in Minnetonka, Minnesota, Zyga Technology has assembled a skilled team with extensive experience in the spine industry. As of late 2017, Zyga operates as a subsidiary of RTI Surgical, Inc.

CVRx is a medical device company that develops implantable technology for the treatment of high blood pressure. Its products include Rheos implantable pulse generator that provides control and delivery of the activation energy; and Rheos carotid sinus leads, which conducts activation energy from the Rheos implantable pulse generator to the left and right carotid arteries. The company also offers a Rheos programmer system that communicates with the Rheos pulse generator. CVRx was founded in 2001 and is based in Minneapolis, Minnesota.

AssureRX Health is a personalized medicine company based in Mason, Ohio, specializing in pharmacogenomics. The company aims to assist healthcare providers in identifying the most suitable medications for individual patients suffering from neuropsychiatric and chronic pain conditions. By offering treatment decision support, AssureRX Health enables clinicians to collect and analyze genetic information, ultimately guiding them in prescribing the right medications tailored to each patient's unique genetic profile. This approach enhances treatment efficacy and patient outcomes in behavioral health and other medical contexts.

EatStreet is an online and mobile food ordering service that streamlines commerce between restaurants and diners. To college students and young professionals, EatStreet is a smart, simple, and affordable way to order delivery and takeout from their favorite restaurants. To restaurant owners, EatStreet is a one-stop-shop for online ordering and marketing. By providing web, mobile, and social products for online ordering, EatStreet brings in new business for restaurants. Diners enjoy the upside of fast, simple ordering while restaurants see their sales soar. Founded in 2010, the company is headquartered in Madison, Wisconsin, United States.

The Mobile Majority is a rapidly growing ad tech startup headquartered in sunny Santa Monica, with offices in New York City, San Francisco, Chicago, and Sao Paulo. We’re a vertically integrated, end-to-end mobile advertising platform. We built mobile first, and from the ground up, our advanced technology reduces redundancy and eliminates waste. As a result, our campaigns run better at a more cost effective price. TMM is led by a team of experienced serial entrepreneurs and media industry veterans - all with a shared passion for eliminating what clients have identified as the biggest issues in mobile today.

aTyr Pharma is a biotherapeutics company based in San Diego, California, specializing in the discovery and development of innovative medicines utilizing novel immunological pathways. The company focuses primarily on ATYR1923, a clinical-stage fusion protein designed to down-regulate immune engagement in interstitial lung diseases by binding to the neuropilin-2 receptor. This candidate is currently undergoing Phase 1b/2a clinical trials. aTyr Pharma has established a strong intellectual property portfolio centered around Physiocrine-based compositions and therapeutic applications, particularly in immunomodulation disorders related to inflammation and immunity. Additionally, the company has formed collaborations with several institutions, including the University of Nebraska Medical Center, CSL Behring, Boston Children’s Hospital, and the Medical University of South Carolina, to advance its research and development efforts. Founded in 2005 by a prominent scientist from The Scripps Research Institute, aTyr is supported by leading life sciences investors.

Signal is the leading SaaS provider of data onboarding and real-time identity resolution. The Signal Open Data Platform helps marketers collect data from any offline or online source, synchronize the data across all touchpoints, and distribute it to any marketing or analytics endpoint – all in real-time. Signal’s technology platform empowers people-based marketers to enhance their customer experience by providing relevance across all channels. Signal was founded in 2009 and is headquartered in Chicago, Illinois, United States.

Horizon Therapeutics operates as a biopharmaceutical company. It focuses on the development of prescription drugs for mild to moderate pain relief and arthritis. The company's product candidates include HZT-501, a proprietary fixed-dose combination formulation of NSAID and ibuprofen; and HZT-602, a combination oral drug product consisting of naproxen and famotidine. Horizon Therapeutics is based in Northbrook, Illinois, and was founded in 2005.

AssureRX Health is a personalized medicine company based in Mason, Ohio, specializing in pharmacogenomics. The company aims to assist healthcare providers in identifying the most suitable medications for individual patients suffering from neuropsychiatric and chronic pain conditions. By offering treatment decision support, AssureRX Health enables clinicians to collect and analyze genetic information, ultimately guiding them in prescribing the right medications tailored to each patient's unique genetic profile. This approach enhances treatment efficacy and patient outcomes in behavioral health and other medical contexts.

Hatch Loyalty Inc. is a provider of a loyalty and rewards platform aimed at small and medium-sized businesses, enabling them to create customized loyalty programs and execute effective marketing campaigns. Founded in 2011 and headquartered in Chicago, Illinois, Hatch offers a suite of tools, including HatchHQ, HatchIQ, and HatchHUB, designed to enhance customer engagement and foster meaningful relationships. The platform also features the industry-leading solution, Belly, which provides off-the-shelf marketing capabilities for businesses. Hatch Loyalty focuses on making customer insights actionable, allowing retailers to tailor experiences and drive loyalty through data-driven decision-making. Previously known as Belly Inc., the company rebranded in September 2017 and operates as a subsidiary of Stuzo Inc.

Endocyte, Inc. is a biopharmaceutical company focused on developing receptor-targeted therapies for cancer and inflammatory diseases. Headquartered in West Lafayette, Indiana, the company creates innovative small molecule drug conjugates (SMDCs) and companion imaging agents. Among its key products, Vintafolide is in Phase IIb clinical trials for non-small cell lung cancer, while EC1456 and EC1169 are in Phase I trials for advanced solid tumors and metastatic castration-resistant prostate cancer, respectively. Additionally, Endocyte is developing several pre-clinical candidates, including EC2629 for cancer treatment and EC2319 for inflammatory diseases. The company has established collaborations with Purdue Research Foundation and other organizations to advance its pipeline. Founded in 1995, Endocyte operates as a subsidiary of Novartis AG.

Nomis Solutions, Inc. is a provider of pricing optimization software designed for retail banking and mortgage lending institutions. The company offers a suite of solutions, including Nomis Mortgage, which delivers real-time market and competitive intelligence to assist lenders in making informed decisions about pricing and margin management. Nomis Price Manager enables financial institutions to implement agile rate management, while Nomis Price Optimizer focuses on portfolio price optimization through advanced analytics and forecasting. Additionally, Nomis Deal Manager enhances customer engagement by providing personalized pricing across various channels. The company also offers pricing advisory services and has facilitated over $600 billion in banking transactions, generating more than $600 million in incremental profits for its clients. Founded in 2002 and headquartered in Brisbane, California, Nomis Solutions maintains offices in Toronto, Canada; Melbourne, Australia; and Beachwood, Ohio, and collaborates with strategic partners like Oliver Wyman and Berkeley Research Group, LLC.