SignalFire

SignalFire is a San Francisco-based venture capital firm that backs seed to early-growth technology companies across North America, investing across sectors including artificial intelligence, machine learning, SaaS, health tech, fintech, cybersecurity, and consumer platforms; it emphasizes data-driven insights and tailored advisory programs to support founders, complementing financing with strategic guidance; SignalFire operates a distributed network of investors and engineers and provides infrastructure to help with recruiting, business development, and customer acquisition, enabling portfolio companies to scale more effectively; the firm partners with entrepreneurs to address core challenges such as talent, market access, and product development, focusing on helping companies accelerate growth and navigate scale.

Rikhil Bajaj

Principal

Taylor Barada

Venture Partner

Heston Berkman

Principal, Venture

Josh Constine

Principal

Adele English

Senior Associate

Past deals in Predictive Analytics

Justpoint

Series A in 2025
Justpoint is an artificial intelligence–driven platform that connects individuals seeking personal injury litigation with suitable attorneys. By applying predictive analytics, it assesses the merits of a claim and helps plaintiffs identify and retain lawyers best suited to their case, while enabling law firms to quickly find cases with merit. The platform also streamlines back-office tasks and discovery processes, improving efficiency for attorneys. With a broad network of more than 1,000 law firms and a database of hundreds of thousands of historical claims, Justpoint operates across 33 states to increase access to justice. The company combines expertise from legal, technical, and medical professionals to provide transparent, data-backed guidance throughout the litigation process.

Qualified Health

Seed Round in 2025
Qualified Health is a technology company specializing in generative artificial intelligence (AI) for the healthcare industry. It offers an infrastructure solution that ensures the safe and effective use of AI in medicine. This includes continuous algorithm performance monitoring, active AI governance, and the development of AI agents tailored to healthcare needs. The company partners with leading health systems to revolutionize healthcare in the United States.

Zeotap

Venture Round in 2024
Founded in 2014, Zeotap operates a customer intelligence platform that helps brands understand their customers and predict behaviors. Its platform connects various data assets across the global advertising ecosystem for end-to-end monetization, collects real-time data to maximize campaign impact, and generates strategic insights. Zeotap serves data owners and advertisers worldwide, with offices in Berlin, New York, Bengaluru, Madrid, and Milan.

Centaur Labs

Series B in 2024
Centaur Labs provides a platform for expert data annotation services, specializing in medical, scientific, and other complex datasets. It leverages a global network of tens of thousands of students and professionals to deliver accurate and scalable solutions.

Unify

Seed Round in 2024
Combine All Models for Faster, Cheaper, and Better Responses Than Any Single Model

CodaMetrix

Series B in 2024
CodaMetrix develops an AI-powered platform for healthcare revenue cycle management. Its platform uses machine learning, deep learning, and natural language processing to autonomously translate clinical notes into billing and diagnostic codes, reducing human workload while maintaining coding accuracy.

Nim

Pre Seed Round in 2024
Generative Video for Professionals

Kolena

Series A in 2023
Kolena is a machine learning testing platform that enables ML teams to rigorously assess their model behavior. It helps identify and track failure modes, enhancing understanding of model performance and identifying gaps for engineering, sales, and customers.

CodaMetrix

Series A in 2023
CodaMetrix develops an AI-powered platform for healthcare revenue cycle management. Its platform uses machine learning, deep learning, and natural language processing to autonomously translate clinical notes into billing and diagnostic codes, reducing human workload while maintaining coding accuracy.

Praisidio

Seed Round in 2021
Praisidio is a provider of augmented intelligence tools that help enterprises manage talent risk. Based in San Francisco and founded in 2019, the company develops AI-driven software to monitor workforce dynamics and support talent management. It integrates with HR and business platforms to answer people-related questions with ChatGPT-like responses and to generate insights through pre-built and customizable reports. The tools are designed to deliver rapid answers and visualizations, enabling organizations to understand retention drivers, identify at-risk roles, and take data-backed actions. Praisidio aims to protect revenue by reducing talent drain through data-driven augmentation of human decision-making, helping enterprise teams care for employees and reduce the cost of turnover.

Kolena

Seed Round in 2021
Kolena is a machine learning testing platform that enables ML teams to rigorously assess their model behavior. It helps identify and track failure modes, enhancing understanding of model performance and identifying gaps for engineering, sales, and customers.

January AI

Venture Round in 2021
January AI, founded in 2017 by Noosheen Hashemi, is a precision health start-up based in Menlo Park, California. The company focuses on empowering individuals to take control of their health by utilizing multi-omic science and artificial intelligence. January AI develops a platform that offers personalized biological insights, enabling users to understand their health through a suite of software and consumer products. One of its key innovations is a virtual continuous glucose monitor that provides real-time glucose insights and predictions, utilizing data from heart rate and glucose levels. This approach allows users to align their health habits with their unique biological needs, facilitating informed decisions regarding diet, exercise, and overall well-being. By prioritizing an integrated health strategy, January AI aims to transform the consumer health landscape, focusing on proactive management rather than reactive treatment.

Zeotap

Series C in 2020
Founded in 2014, Zeotap operates a customer intelligence platform that helps brands understand their customers and predict behaviors. Its platform connects various data assets across the global advertising ecosystem for end-to-end monetization, collects real-time data to maximize campaign impact, and generates strategic insights. Zeotap serves data owners and advertisers worldwide, with offices in Berlin, New York, Bengaluru, Madrid, and Milan.

PreDxion Bio

Seed Round in 2020
PreDxion Bio is an early-stage healthcare company revolutionizing testing and treatment through low-cost, user-friendly at-home diagnostics. Enabled by PreDxion’s proprietary multiplexed localized surface plasmon resonance (LSPR) technology, our first product is a rapid, saliva-based test for COVID-19, flu, pneumonia, common cold, and other respiratory diseases.

Zendrive

Series B in 2019
Zendrive is a mobility data analytics company that uses smartphone sensor data to monitor driving behavior and traffic dynamics, producing actionable insights to improve road safety for passengers and drivers. The company’s AI-powered platform analyzes signals such as speed, location, direction, acceleration, speeding, hard braking, and phone usage, and can detect collision events. It enables safety improvements through behavioral coaching and incentives and supports timely interventions in moments of truth. Zendrive serves transportation stakeholders including on-demand and commercial fleets, leveraging data to help manage safety as mobility shifts toward shared and on-demand transportation. Headquartered in San Francisco, Zendrive was established to advance safety through data and analytics.

Juvo

Series B in 2017
Juvo Mobile Inc. is focused on creating financial identities for creditworthy individuals who are often excluded from traditional financial systems. Founded in 2014 and headquartered in San Francisco, with additional offices in São Paulo, Singapore, and Miami, Juvo collaborates with mobile network operators to leverage its proprietary Identity Scoring technology. This technology utilizes data science, machine learning, and game mechanics to develop identity-based relationships with prepaid users, thereby facilitating access to mobile financial services that were previously unattainable. By transforming subscriber consumption with real-time credit, Juvo aims to deepen connections between mobile operators and their subscribers, ultimately enhancing their ability to provide essential financial services. The company is privately held and supported by prominent figures in technology, mobile, and finance.

Nim

Generative Video for Professionals

Persist AI

Persist AI is a company that aids pharmaceutical firms in the development of long-acting drug formulations by leveraging artificial intelligence and automation. Traditional formulation development is a lengthy process, typically spanning 5 to 10 years, which includes extensive pre-clinical and clinical testing phases. Persist AI aims to significantly reduce this timeline by streamlining pre-clinical formulation development to just three months, enhancing the efficiency of the drug development process by 50%. The company employs AI-driven automation technologies, such as automated drug release testing and high-throughput formulation screening, to facilitate quicker and more reliable drug formulation. By doing so, Persist AI not only accelerates drug development but also contributes to improving patient outcomes.
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