S2G Investments

S2G Ventures is a venture capital firm based in Chicago, established in 2014, that focuses on investing in the food and agriculture sectors. The firm aims to support entrepreneurs whose products and services address the growing consumer demand for healthy, sustainable, and locally sourced food. S2G Ventures identifies key areas within the food system that are poised for innovation and change, creating a diverse portfolio that includes seed, venture, and growth-stage investments. Its investment interests span various domains, including agriculture, ingredients, infrastructure and logistics, food safety and technology, retail and restaurants, and consumer brands.

Kate Danaher

Managing Director

Matthew Walker

Managing Director

Past deals in Nutrition

Big Bold Health

Series B in 2025
Big Bold Health is a company focused on providing immune health solutions by combining natural ingredients with scientific research. It produces a range of health and wellness products aimed at enhancing both human and planetary health. The product lineup includes immune-supporting nutrition flour, capsules, protein shake mixes, and cod liver oil. These offerings are designed to address immune dysfunction and promote overall well-being, enabling individuals to reclaim their health through natural means.

Shiru

Series B in 2024
Shiru, Inc. is a food technology company based in Oakland, California, established in 2019. The company specializes in developing and producing edible proteins aimed at replacing dairy products and eggs in the food industry. By leveraging artificial intelligence and computational design, Shiru creates enhanced proteins that contribute to sustainable food production. The company's focus on using bioinformatics and precision biology allows it to discover novel natural proteins, thereby enabling clients to replace harmful ingredients with healthier alternatives.

Mend

Series A in 2023
MEND is a life sciences company dedicated to advancing health and recovery through targeted clinical nutrition and medical food interventions. The company focuses on researching and developing products that enhance patient outcomes in various contexts, including injury recovery, surgical recovery, aging, and physical performance. MEND's solutions have been widely adopted by hospitals, health systems, and professional sports teams across major leagues, as well as by the elite forces of the US Military. Through its commitment to ongoing research and development, MEND aims to empower caregivers and improve health outcomes for individuals facing diverse health challenges.

UCAN

Series A in 2022
UCAN specializes in providing energy, hydration, and protein products designed to deliver sustained energy without the use of sugar or caffeine. Their offerings include natural, slow-releasing carbohydrates that help to stabilize blood sugar levels, thereby preventing the typical spikes and crashes associated with traditional sugar-based products. This approach allows health-conscious consumers to achieve prolonged energy, making it easier for them to burn fat for fuel while maintaining digestive comfort. UCAN's focus on innovative energy solutions caters to individuals seeking healthier alternatives for their active lifestyles.

Shiru

Series A in 2022
Shiru, Inc. is a food technology company based in Oakland, California, established in 2019. The company specializes in developing and producing edible proteins aimed at replacing dairy products and eggs in the food industry. By leveraging artificial intelligence and computational design, Shiru creates enhanced proteins that contribute to sustainable food production. The company's focus on using bioinformatics and precision biology allows it to discover novel natural proteins, thereby enabling clients to replace harmful ingredients with healthier alternatives.

Eat The Change

Venture Round in 2022
Eat the Change is a company focused on creating nutritious and environmentally friendly snacks. Founded by activist entrepreneur Seth Goldman and celebrity chef Spike Mendelsohn, the company aims to empower consumers to make dietary choices that align with their health and environmental concerns. Eat the Change produces a range of chef-crafted products, including organic mushroom jerky, which provide essential vitamins while promoting sustainability. Through its offerings, the company seeks to deliver delicious snacks that positively impact both personal well-being and the planet.

Faeth Therapeutics

Series A in 2022
Faeth Therapeutics is a healthcare company dedicated to enhancing cancer treatment through a deep understanding of the relationship between dietary nutrients and tumor growth. By aligning specific diets with tumor genotypes and treatment regimens, Faeth aims to limit the energy and resources that tumors need to proliferate, thereby improving patient outcomes in cancer therapy. Founded by leading researchers and clinicians, the company seeks to translate significant discoveries from cancer research laboratories into effective clinical practices, focusing on evidence-based approaches to optimize treatment strategies for cancer patients.

MycoTechnology

Series E in 2022
MycoTechnology is a food technology company based in Aurora, Colorado, that focuses on enhancing the flavor and nutritional value of agricultural products through fungi-based food-processing platforms. Founded in 2013, the company addresses various challenges in the food, beverage, and flavor industries by utilizing gourmet fungi and mycelial fermentation. One of its notable products, ClearTaste, is an all-natural, GMO-free, organic bitter blocker that is both Kosher and Halal certified, designed to improve the taste of various agricultural products. In addition, MycoTechnology offers myceliated chocolate and works with robusta and arabica coffee beans, developing and licensing technology to enhance their flavor profiles. By integrating these innovative solutions, the company aims to help food producers incorporate healthier ingredients and strengthen their brand associations.

Once Upon a Farm

Series D in 2022
Once Upon a Farm is a producer of nutritious, cold-pressed organic snacks and meals designed for children from babies to older kids. The company specializes in a variety of products, including fruit and vegetable blends, dairy-free smoothies, overnight oats, and baby food options. Utilizing high-pressure processing technology, Once Upon a Farm ensures that its offerings retain optimal flavor, aroma, color, texture, and nutrients, promoting healthy nutrition and palate development in young children. The company is dedicated to nurturing both children and the environment by providing fresh, organic, and healthy food choices for families.

Big Bold Health

Series A in 2022
Big Bold Health is a company focused on providing immune health solutions by combining natural ingredients with scientific research. It produces a range of health and wellness products aimed at enhancing both human and planetary health. The product lineup includes immune-supporting nutrition flour, capsules, protein shake mixes, and cod liver oil. These offerings are designed to address immune dysfunction and promote overall well-being, enabling individuals to reclaim their health through natural means.

NourishedRx

Seed Round in 2022
NourishedRx is a provider of personalized food solutions aimed at health plan members and patients with diet-sensitive chronic health conditions, particularly those experiencing nutrition insecurity. Founded in 2019 in Stamford, Connecticut, the company delivers customized meal plans and meal prep kits tailored to individual eating habits. In addition to food solutions, NourishedRx offers educational resources and support to promote lasting behavior change, ultimately enhancing member engagement and satisfaction. The company's approach is designed to improve clinical outcomes and deliver significant cost savings for both individuals and healthcare systems.

Faeth Therapeutics

Seed Round in 2022
Faeth Therapeutics is a healthcare company dedicated to enhancing cancer treatment through a deep understanding of the relationship between dietary nutrients and tumor growth. By aligning specific diets with tumor genotypes and treatment regimens, Faeth aims to limit the energy and resources that tumors need to proliferate, thereby improving patient outcomes in cancer therapy. Founded by leading researchers and clinicians, the company seeks to translate significant discoveries from cancer research laboratories into effective clinical practices, focusing on evidence-based approaches to optimize treatment strategies for cancer patients.

Shiru

Series A in 2021
Shiru, Inc. is a food technology company based in Oakland, California, established in 2019. The company specializes in developing and producing edible proteins aimed at replacing dairy products and eggs in the food industry. By leveraging artificial intelligence and computational design, Shiru creates enhanced proteins that contribute to sustainable food production. The company's focus on using bioinformatics and precision biology allows it to discover novel natural proteins, thereby enabling clients to replace harmful ingredients with healthier alternatives.

Ripple Foods

Series E in 2021
Ripple Foods specializes in producing high-quality, dairy-free milk alternatives that prioritize nutrition and taste. Their products are designed to be high in protein, offering eight times the protein found in almond milk while containing half the sugar of traditional dairy milk. Additionally, Ripple's beverages are rich in bioavailable calcium, providing 50% more than regular milk, and are a good source of potassium and omega-3 fatty acids. With a focus on delivering a creamy texture that enhances the drinking experience, Ripple aims to provide a satisfying alternative for those seeking non-dairy options without sacrificing flavor or nutritional value.

Once Upon a Farm

Series C in 2021
Once Upon a Farm is a producer of nutritious, cold-pressed organic snacks and meals designed for children from babies to older kids. The company specializes in a variety of products, including fruit and vegetable blends, dairy-free smoothies, overnight oats, and baby food options. Utilizing high-pressure processing technology, Once Upon a Farm ensures that its offerings retain optimal flavor, aroma, color, texture, and nutrients, promoting healthy nutrition and palate development in young children. The company is dedicated to nurturing both children and the environment by providing fresh, organic, and healthy food choices for families.

GEM

Seed Round in 2021
GEM Health, Inc. specializes in manufacturing plant-based multivitamin supplements aimed at enhancing wellbeing and reducing stress for women. Founded in 2018 and based in Los Angeles, California, the company offers a chewable daily nutrition product made from 13 whole plant ingredients that provide over 15 essential vitamins, minerals, and herbs without fillers or preservatives. GEM's approach emphasizes the use of real, sustainable ingredients, blending minerals and probiotics to promote health at the cellular level. In addition to its nutritional products, the company sells apparel such as sweatshirts and tote bags through its online platform.

Food In-Depth

Series B in 2021
Food In-Depth operates a food testing platform designed to verify food safety and authenticate label claims. The company utilizes a thorough and near real-time proprietary process to detect the presence of antibiotics and other substances in pork, beef, and poultry. By collaborating with innovative food companies, Food In-Depth aims to enhance transparency and accountability in brand labeling. Their rigorous testing ensures that food suppliers can provide clean and healthy products to consumers, thereby fostering trust in food safety standards. As they expand their testing capabilities to additional food categories, Food In-Depth remains committed to upholding high standards in the food industry.

EVR Foods (Lavva)

Convertible Note in 2021
EVR Foods is a producer of plant-based foods intended to offer nourishing and functional food alternatives. Their products are naturally dairy-free, soy-free, and gluten-free and have a blend of creamy, sprouted pili nuts, and prebiotic-rich plantains, enabling consumers to adopt healthy eating habits without compromising on taste.

Project Well

Convertible Note in 2020
Project Well, Inc. is a health technology platform based in Stamford, Connecticut, that specializes in delivering prepared meals, meal kits, produce boxes, and food gift cards online. Founded in 2019 by Lauren Driscoll, the company focuses on providing personalized food and nutrition solutions specifically tailored for Medicare advantage members who have chronic diseases or are at risk of food insecurity. By sourcing healthy food vendors and integrating clinical context and individual preferences, Project Well aims to improve nutritional outcomes for its users while addressing food accessibility challenges.

EVR Foods (Lavva)

Convertible Note in 2020
EVR Foods is a producer of plant-based foods intended to offer nourishing and functional food alternatives. Their products are naturally dairy-free, soy-free, and gluten-free and have a blend of creamy, sprouted pili nuts, and prebiotic-rich plantains, enabling consumers to adopt healthy eating habits without compromising on taste.

MycoTechnology

Series D in 2020
MycoTechnology is a food technology company based in Aurora, Colorado, that focuses on enhancing the flavor and nutritional value of agricultural products through fungi-based food-processing platforms. Founded in 2013, the company addresses various challenges in the food, beverage, and flavor industries by utilizing gourmet fungi and mycelial fermentation. One of its notable products, ClearTaste, is an all-natural, GMO-free, organic bitter blocker that is both Kosher and Halal certified, designed to improve the taste of various agricultural products. In addition, MycoTechnology offers myceliated chocolate and works with robusta and arabica coffee beans, developing and licensing technology to enhance their flavor profiles. By integrating these innovative solutions, the company aims to help food producers incorporate healthier ingredients and strengthen their brand associations.

Once Upon a Farm

Convertible Note in 2020
Once Upon a Farm is a producer of nutritious, cold-pressed organic snacks and meals designed for children from babies to older kids. The company specializes in a variety of products, including fruit and vegetable blends, dairy-free smoothies, overnight oats, and baby food options. Utilizing high-pressure processing technology, Once Upon a Farm ensures that its offerings retain optimal flavor, aroma, color, texture, and nutrients, promoting healthy nutrition and palate development in young children. The company is dedicated to nurturing both children and the environment by providing fresh, organic, and healthy food choices for families.

Everytable

Series A in 2020
Everytable is a company focused on providing nutritious and affordable meals through grab-and-go locations. Its mission is to transform the food system to ensure that fresh, healthy food is accessible to everyone, regardless of their background. By operating a tech-driven casual restaurant platform, Everytable offers made-from-scratch meals at lower prices, achieved by streamlining traditional restaurant costs. This approach enables consumers to conveniently order wholesome food online, promoting greater access to healthy dining options in various communities.

Shiru

Seed Round in 2019
Shiru, Inc. is a food technology company based in Oakland, California, established in 2019. The company specializes in developing and producing edible proteins aimed at replacing dairy products and eggs in the food industry. By leveraging artificial intelligence and computational design, Shiru creates enhanced proteins that contribute to sustainable food production. The company's focus on using bioinformatics and precision biology allows it to discover novel natural proteins, thereby enabling clients to replace harmful ingredients with healthier alternatives.

Kuli Kuli

Series B in 2019
Kuli Kuli, Inc. is a producer of nutritional moringa products based in Oakland, California. Founded in 2011 by Anne Tsuei, Jordan Moncharmont, Lisa Curtis, and Valerie Popelka, the company offers a range of products, including moringa bars, moringa powders, green energy shots, herbal teas, and sampler packs. Kuli Kuli markets its products through both retail stores and online channels, aiming to provide health-conscious consumers with the benefits of moringa, a nutrient-rich superfood.

MycoTechnology

Series C in 2019
MycoTechnology is a food technology company based in Aurora, Colorado, that focuses on enhancing the flavor and nutritional value of agricultural products through fungi-based food-processing platforms. Founded in 2013, the company addresses various challenges in the food, beverage, and flavor industries by utilizing gourmet fungi and mycelial fermentation. One of its notable products, ClearTaste, is an all-natural, GMO-free, organic bitter blocker that is both Kosher and Halal certified, designed to improve the taste of various agricultural products. In addition, MycoTechnology offers myceliated chocolate and works with robusta and arabica coffee beans, developing and licensing technology to enhance their flavor profiles. By integrating these innovative solutions, the company aims to help food producers incorporate healthier ingredients and strengthen their brand associations.

Once Upon a Farm

Series B in 2018
Once Upon a Farm is a producer of nutritious, cold-pressed organic snacks and meals designed for children from babies to older kids. The company specializes in a variety of products, including fruit and vegetable blends, dairy-free smoothies, overnight oats, and baby food options. Utilizing high-pressure processing technology, Once Upon a Farm ensures that its offerings retain optimal flavor, aroma, color, texture, and nutrients, promoting healthy nutrition and palate development in young children. The company is dedicated to nurturing both children and the environment by providing fresh, organic, and healthy food choices for families.

UCAN

Series D in 2018
UCAN specializes in providing energy, hydration, and protein products designed to deliver sustained energy without the use of sugar or caffeine. Their offerings include natural, slow-releasing carbohydrates that help to stabilize blood sugar levels, thereby preventing the typical spikes and crashes associated with traditional sugar-based products. This approach allows health-conscious consumers to achieve prolonged energy, making it easier for them to burn fat for fuel while maintaining digestive comfort. UCAN's focus on innovative energy solutions caters to individuals seeking healthier alternatives for their active lifestyles.

Ripple Foods

Series C in 2018
Ripple Foods specializes in producing high-quality, dairy-free milk alternatives that prioritize nutrition and taste. Their products are designed to be high in protein, offering eight times the protein found in almond milk while containing half the sugar of traditional dairy milk. Additionally, Ripple's beverages are rich in bioavailable calcium, providing 50% more than regular milk, and are a good source of potassium and omega-3 fatty acids. With a focus on delivering a creamy texture that enhances the drinking experience, Ripple aims to provide a satisfying alternative for those seeking non-dairy options without sacrificing flavor or nutritional value.

MycoTechnology

Series B in 2017
MycoTechnology is a food technology company based in Aurora, Colorado, that focuses on enhancing the flavor and nutritional value of agricultural products through fungi-based food-processing platforms. Founded in 2013, the company addresses various challenges in the food, beverage, and flavor industries by utilizing gourmet fungi and mycelial fermentation. One of its notable products, ClearTaste, is an all-natural, GMO-free, organic bitter blocker that is both Kosher and Halal certified, designed to improve the taste of various agricultural products. In addition, MycoTechnology offers myceliated chocolate and works with robusta and arabica coffee beans, developing and licensing technology to enhance their flavor profiles. By integrating these innovative solutions, the company aims to help food producers incorporate healthier ingredients and strengthen their brand associations.

Kuli Kuli

Series A in 2017
Kuli Kuli, Inc. is a producer of nutritional moringa products based in Oakland, California. Founded in 2011 by Anne Tsuei, Jordan Moncharmont, Lisa Curtis, and Valerie Popelka, the company offers a range of products, including moringa bars, moringa powders, green energy shots, herbal teas, and sampler packs. Kuli Kuli markets its products through both retail stores and online channels, aiming to provide health-conscious consumers with the benefits of moringa, a nutrient-rich superfood.

Ripple Foods

Series B in 2016
Ripple Foods specializes in producing high-quality, dairy-free milk alternatives that prioritize nutrition and taste. Their products are designed to be high in protein, offering eight times the protein found in almond milk while containing half the sugar of traditional dairy milk. Additionally, Ripple's beverages are rich in bioavailable calcium, providing 50% more than regular milk, and are a good source of potassium and omega-3 fatty acids. With a focus on delivering a creamy texture that enhances the drinking experience, Ripple aims to provide a satisfying alternative for those seeking non-dairy options without sacrificing flavor or nutritional value.

MycoTechnology

Series A in 2015
MycoTechnology is a food technology company based in Aurora, Colorado, that focuses on enhancing the flavor and nutritional value of agricultural products through fungi-based food-processing platforms. Founded in 2013, the company addresses various challenges in the food, beverage, and flavor industries by utilizing gourmet fungi and mycelial fermentation. One of its notable products, ClearTaste, is an all-natural, GMO-free, organic bitter blocker that is both Kosher and Halal certified, designed to improve the taste of various agricultural products. In addition, MycoTechnology offers myceliated chocolate and works with robusta and arabica coffee beans, developing and licensing technology to enhance their flavor profiles. By integrating these innovative solutions, the company aims to help food producers incorporate healthier ingredients and strengthen their brand associations.

ShopWell

Series C in 2015
ShopWell Labs, Inc. is a technology company based in San Carlos, California, that specializes in personalized nutrition through its website and mobile application. Founded in 2008, the platform offers users tailored food recommendations based on individual dietary needs, helping them build healthy grocery lists. By scanning a food's barcode, users can access detailed nutrition information, allergy alerts, and ingredient analysis, allowing them to make informed choices while grocery shopping. ShopWell aims to simplify the process of selecting nutritious foods and supports users in achieving health goals such as weight management and dietary restrictions. The app is designed to help users incorporate desired nutrients while avoiding allergens and unwanted ingredients. As a Community Partner of the USDA and certified by Registered Dietitians, ShopWell provides a user-friendly, free resource for individuals and families seeking to improve their dietary habits.
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