Rex Health Ventures

Rex Health Ventures, established in 2012 and based in Raleigh, North Carolina, is the corporate venture capital arm of UNC REX Healthcare. The organization focuses on supporting the discovery and development of innovative healthcare solutions, including treatments, tools, products, and services. By investing in and collaborating with entrepreneurs and companies, Rex Health Ventures aims to facilitate the introduction of new offerings into the healthcare marketplace. The firm targets seed-stage, early-stage, and later-stage investments primarily in the healthcare, software as a service, life sciences, and health technology sectors within the United States. Through its strategic initiatives, Rex Health Ventures is committed to enhancing patient care and addressing the challenges faced by early-stage healthcare startups.

Evan Bernath

Investment Associate

Ray Jang

Senior Associate

Anita Watkins

Managing Director

21 past transactions

Synaptrix

Series A in 2024
Synaptrix is committed to offering free of drugs, lasting alternatives for postoperative pain treatment using NOVABLOC.

Arrivo BioVentures

Series B in 2023
Arrivo BioVentures LLC is a biopharmaceutical company based in Morrisville, North Carolina, established in 2015. The company specializes in the development of biologics and small molecules aimed at enhancing patient care. Arrivo BioVentures focuses on reformulating existing drugs and creating new chemical entities, employing its expertise to navigate regulatory strategies that streamline the approval process. By collaborating closely with regulatory bodies such as the FDA, the company aims to minimize unexpected challenges and accelerate the implementation of its clinical programs. Through its innovative approach, Arrivo BioVentures seeks to meet the demands of the biotechnology sector while prioritizing the improvement of patient outcomes.

Censinet

Venture Round in 2023
Censinet, Inc. is a healthcare-focused SaaS company that offers a cloud-based platform for managing third-party risk assessments. Founded in 2017 and based in Winchester, Massachusetts, Censinet connects healthcare providers with their vendors, streamlining the process of assessing and managing risks in real time. The platform eliminates the need for inefficient spreadsheets and manual workflows by automating risk assessments and providing continuous insights into vendor profiles. This approach enables healthcare organizations to identify and address potential threats within their vendor ecosystem effectively, enhancing overall cybersecurity and operational efficiency.

Vergent Bioscience

Series B in 2022
Vergent Bioscience, Inc. specializes in developing tumor-targeted fluorescent probes that enhance the surgical removal of cancerous tissue. Founded in 2013 and based in Minneapolis, Minnesota, the company’s flagship product, VGT-309, is a molecularly-targeted imaging molecule designed to bind to enzymes overexpressed in various tumor tissues. Upon injection before surgery, VGT-309 activates a brightly fluorescing dye, enabling surgeons to visually distinguish cancerous tissue from normal tissue during procedures. This technology aims to improve surgical outcomes by ensuring the complete removal of tumors, which is crucial for increasing cure rates. Vergent Bioscience's innovative approach addresses a significant clinical need for advanced visualization in various surgical settings, including open, laparoscopic, and robotic surgeries.

Pryon

Funding Round in 2021
Pryon Inc. is an artificial intelligence company based in Raleigh, North Carolina, that focuses on enhancing enterprise knowledge management. Founded in 2017 by Igor Jablokov, Pryon develops an augmented intelligence platform that combines human and machine capabilities to streamline access to information across various channels and sources. The platform employs natural language processing and automated machine learning to transform unstructured data into actionable insights, thereby boosting productivity and decision-making accuracy. By utilizing a no-code approach, Pryon enables organizations to quickly harness the value of their information assets without disrupting existing operations. The company's solutions aim to simplify AI adoption, reduce complexity, and lower costs for businesses seeking to improve their workflows and knowledge utilization.

BioStable

Series C in 2020
BioStable Science & Engineering, Inc. is a cardiovascular device company based in Austin, Texas, that specializes in developing valve repair technologies as alternatives to valve replacement for patients with aortic valve disease. The company offers a range of HAART aortic valve repair technologies, including the HAART 300 aortic annuloplasty device, designed to reduce annular dilatation and restore three-dimensional annular geometry, and the HAART 200 device tailored for bicuspid aortic valve repair. Additionally, BioStable's aortic root restoration system aims to enhance surgical outcomes for patients with aortic insufficiency or aortic root aneurysm. Founded in 2008, BioStable leverages its expertise in product development, regulatory affairs, and clinical validation to minimize time to market for its innovative medical devices, ultimately improving patient care in the cardiovascular field.

Bardy Diagnostics

Series B in 2019
Bardy Diagnostics is a developer of a cardiac monitor and arrhythmia detection device. The company has created a new, state-of-the-art heart monitor known as Carnation Ambulatory Monitor (CAM) that can be worn comfortably and discreetly for up to 7 days. Unlike many other heart monitors, CAM can be worn during exercise or while showering. Its unique, narrow, hourglass shape makes it especially advantageous for the female anatomy. It is also designed to be comfortable for women to wear, with its narrow, hourglass shape. Bardy Diagnostics uses his expertise to develop cardiac monitoring solutions that help physicians obtain more accurate information about actionable events in the hopes of saving lives. The company's mission is to improve clinical management and outcomes for patients and their physicians by employing innovative P-wave centric ECG detection into patient-friendly technologies that result in greater patient compliance and more confident physician diagnoses. Bardy Diagnostics was founded in 2013 and is headquartered in Seattle, Washington, USA.

Phynd Technologies

Series B in 2019
Phynd Technologies Inc. operates a Software-as-a-Service data management platform designed to streamline healthcare provider data management for healthcare organizations in the United States. The company's Unified Provider Management (UPM) platform centralizes critical provider data, enabling organizations to effectively gather, manage, and share information across various IT systems. This enhances financial performance and clinical outcomes while minimizing compliance risks. Key features of the platform include tools for managing billing addresses, communication preferences, licensing, and provider enrollment in real-time. Phynd's services are utilized by over 350 hospitals and more than 20,000 locations across the country, allowing these entities to maintain a comprehensive hub of provider data for applications in electronic health records, marketing, and claims systems. Founded in 2012 and headquartered in Dallas, Texas, Phynd Technologies has established partnerships to further enhance its service offerings.

Gauss Surgical

Series C in 2018
Gauss Surgical, Inc. specializes in real-time blood monitoring solutions that enhance clinical decision-making in the healthcare sector. The company has developed a vision-based platform that provides accurate estimations of blood loss, facilitating timely transfusion decisions and improving patient outcomes. Its flagship product, Triton, is utilized in obstetrics to aid in the early detection of postpartum hemorrhage and offers objective metrics for assessing blood loss. Additionally, Gauss Surgical offers Triton OR, designed for operating rooms to measure blood loss from surgical sponges and suction canisters, and Triton L&D, which focuses on vaginal delivery and postpartum care. Founded in 2011, Gauss Surgical operates from its headquarters in Menlo Park, California.

Emergo Therapeutics

Series A in 2018
Emergo Therapeutics is a pharmaceutical startup that develops treatment options for flu-like illnesses. It is focused on developing drugs to modulate inflammatory cytokines and improve the functioning of the immune system in various potential indications, starting with infectious diseases. Emergo’s therapeutic interventions are focused on reducing the production of inflammatory cytokines from mast cells. Emergo is headquartered in Durham, North Carolina.

Target PharmaSolutions

Series A in 2016
TARGET PharmaSolutions, Inc. specializes in providing real-world data solutions to enhance drug development and commercialization processes. Established in 2015 in Durham, North Carolina, the company focuses on creating custom datasets and analyses to address complex healthcare evidence questions. TARGET PharmaSolutions offers comprehensive health evidence solutions that aggregate real-world data from a network of participating sites, alongside bio specimen samples and consulting services. The company emerged from the success of HCV-TARGET, a model developed for Hepatitis C that has garnered significant investment and involvement from the FDA. This background has positioned TARGET PharmaSolutions to effectively support sponsors in expanding product labels and reducing the need for costly Phase IV studies.

Phononic

Series E in 2016
Phononic is a growth stage, semiconductor hardware company commercializing solid-state heat pumps and fully integrated systems that displace compressors, heat sinks, and fans for electronics cooling; residential and commercial refrigeration; and climate control. The company’s disruptive approach combines high-performance solid-state heat pumps integrated into a manufacturing-friendly systems architecture that realizes products that are smart, sustainable, and solid state-driven.

Bluesight

Series C in 2016
Bluesight addresses supply chain inefficiencies in healthcare by offering actionable analytics throughout the medication lifecycle. The company has developed a hospital inventory management platform that automates pharmacy kit processing and medication tracking, aiming to streamline the often cumbersome and error-prone manual processes associated with medication handling. By implementing automation technology, Bluesight enhances operational efficiency, improves patient safety, and increases medication visibility within hospitals. Through its suite of Medication Intelligence solutions, the company simplifies the complexities of medication management, providing healthcare professionals with the tools needed for better decision-making and risk reduction.

Arrivo BioVentures

Series A in 2016
Arrivo BioVentures LLC is a biopharmaceutical company based in Morrisville, North Carolina, established in 2015. The company specializes in the development of biologics and small molecules aimed at enhancing patient care. Arrivo BioVentures focuses on reformulating existing drugs and creating new chemical entities, employing its expertise to navigate regulatory strategies that streamline the approval process. By collaborating closely with regulatory bodies such as the FDA, the company aims to minimize unexpected challenges and accelerate the implementation of its clinical programs. Through its innovative approach, Arrivo BioVentures seeks to meet the demands of the biotechnology sector while prioritizing the improvement of patient outcomes.

Veran Medical Technologies

Venture Round in 2015
Veran Medical Technologies is a medical device company focused on developing minimally invasive solutions for interventional oncology procedures. Based in St. Louis, Missouri, the company offers a range of products, including the SPiNView thoracic navigation system, which aids physicians in performing biopsies on solitary pulmonary nodules for early lung cancer diagnosis. Other key offerings include the ig4 IR System, a platform that assists in biopsies and ablations for various organs, and the SPiNPerc device for hybrid diagnostic procedures. The company also provides vPad2, a tracking device for instrument positioning during surgery, and the vTrack 2.0 Instruments, which guide physicians to peripheral lung regions. Veran's technology enhances diagnostic accuracy and therapy delivery by integrating various imaging modalities, ultimately aiming to improve patient outcomes through earlier cancer detection and treatment.

Baebies

Series A in 2015
Baebies, Inc. is a company based in Durham, North Carolina, that specializes in manufacturing screening and pediatric testing equipment for newborns. Founded in 2014 by Richard West and Vamsee Pamula, Baebies developed its newborn screening platform, SEEKER, which is FDA authorized and CE marked. SEEKER enables the simultaneous performance of multiple assays to quantitatively measure the activity of lysosomal enzymes from a single dried blood spot specimen. Additionally, the company produces the FINDER near-patient testing equipment, which also holds CE marking, and the FINDER 1.5 platform, which includes a SARS-CoV-2 test with emergency use notification from the FDA. Baebies utilizes digital microfluidics technology, allowing for efficient diagnostics from low-volume samples, and aims to enhance early disease detection for both children and adults. The company serves hospitals and public health labs, focusing on improving newborn health outcomes and providing innovative diagnostic solutions.

Bluesight

Series B in 2015
Bluesight addresses supply chain inefficiencies in healthcare by offering actionable analytics throughout the medication lifecycle. The company has developed a hospital inventory management platform that automates pharmacy kit processing and medication tracking, aiming to streamline the often cumbersome and error-prone manual processes associated with medication handling. By implementing automation technology, Bluesight enhances operational efficiency, improves patient safety, and increases medication visibility within hospitals. Through its suite of Medication Intelligence solutions, the company simplifies the complexities of medication management, providing healthcare professionals with the tools needed for better decision-making and risk reduction.

Carta Healthcare

Carta Healthcare, Inc. is a technology company that provides a software-as-a-service platform designed to improve patient care in hospitals. Founded in 2016 and headquartered in San Mateo, California, the platform leverages existing IT data to describe patient journeys and predict potential bottlenecks, such as recovery bed shortages and cancellations. By employing machine learning, Carta Healthcare enables hospitals to personalize care, allowing them to identify past patients with similar profiles and analyze their experiences. This approach enhances the efficiency and quality of healthcare data management by combining artificial intelligence with skilled human expertise, facilitating more effective and cost-efficient data abstraction for health systems.
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