Queen City Angels

Queen City Angels (QCA) is an angel investment group based in Cincinnati, Ohio, established in 2000. The organization comprises experienced, accredited investors dedicated to fostering the growth of early-stage companies in Cincinnati and its surrounding areas. QCA focuses its investments on a diverse range of sectors, including advanced materials, life sciences, media, retail, electrical devices and supplies, financial services, and information technology. Through strategic investments, QCA aims to support entrepreneurs and drive substantial returns while contributing to the economic development of the region.

John Lilly

Investor Member

Tony Shipley

Chairman and Co-Founder

Past deals in Ohio

Kurome Therapeutics

Series A in 2021
Kurome Therapeutics, Inc. is a preclinical stage company based in Cincinnati, Ohio, focused on developing innovative therapies to combat cancer. The company targets cancer cells that have hijacked immune signaling pathways, allowing them to evade traditional treatments and develop resistance. By creating inhibitors that disrupt these dysregulated immune signaling mechanisms, Kurome Therapeutics aims to enhance the effectiveness of cancer therapies, particularly for hematological cancers. Founded in 2019, the company is dedicated to addressing the challenges of cancer treatment by providing new options that aim to overcome the survival tactics employed by cancer cells.

Standard Bariatrics

Series B in 2021
Standard Bariatrics is a medical device company based in Cincinnati, Ohio, founded in 2014. The company specializes in developing surgical instruments designed specifically for weight-loss surgeries, particularly laparoscopic sleeve gastrectomy. One of its key products, the Standard Clamp, enables surgeons to standardize their techniques, thereby reducing variation and improving efficiency during procedures. The company’s tools are intended to be used alongside general-use endoscopic staplers with reloadable cartridges, which helps to minimize the number of cartridges required for each surgery. This innovation not only lowers costs for healthcare providers but also assists in creating consistent surgical outcomes.

Airway Therapeutics

Series B in 2019
Airway Therapeutics, Inc. is a biopharmaceutical company focused on developing protein therapeutics for lung and pediatric applications. Based in Cincinnati, Ohio, with additional offices in Marietta, Georgia, the company specializes in products like recombinant human surfactant protein-D, aimed at preventing bronchopulmonary dysplasia in premature infants, and AT100, a protein replacement therapy for the same condition. The company licenses technology from the pulmonary research program of Cincinnati Children's Hospital Medical Center, which supports the development of multiple products targeting various lung disorders. Airway Therapeutics aims to address the cycle of injury and inflammation in patients with respiratory and inflammatory diseases through advanced biologics that reduce inflammation, infection, and modulate immune responses, ultimately improving treatment outcomes.

Standard Bariatrics

Series A in 2018
Standard Bariatrics is a medical device company based in Cincinnati, Ohio, founded in 2014. The company specializes in developing surgical instruments designed specifically for weight-loss surgeries, particularly laparoscopic sleeve gastrectomy. One of its key products, the Standard Clamp, enables surgeons to standardize their techniques, thereby reducing variation and improving efficiency during procedures. The company’s tools are intended to be used alongside general-use endoscopic staplers with reloadable cartridges, which helps to minimize the number of cartridges required for each surgery. This innovation not only lowers costs for healthcare providers but also assists in creating consistent surgical outcomes.

Airway Therapeutics

Series B in 2018
Airway Therapeutics, Inc. is a biopharmaceutical company focused on developing protein therapeutics for lung and pediatric applications. Based in Cincinnati, Ohio, with additional offices in Marietta, Georgia, the company specializes in products like recombinant human surfactant protein-D, aimed at preventing bronchopulmonary dysplasia in premature infants, and AT100, a protein replacement therapy for the same condition. The company licenses technology from the pulmonary research program of Cincinnati Children's Hospital Medical Center, which supports the development of multiple products targeting various lung disorders. Airway Therapeutics aims to address the cycle of injury and inflammation in patients with respiratory and inflammatory diseases through advanced biologics that reduce inflammation, infection, and modulate immune responses, ultimately improving treatment outcomes.

Supply Dynamics

Series A in 2017
Supply Dynamics, Inc. is a provider of a cloud-based supply chain management platform designed to enhance visibility and control over materials and raw inventory. Founded in 2003 and based in Loveland, Ohio, the company serves various industries, including aerospace and defense, automotive, electronics, energy, industrial manufacturing, mining, and oil and gas. Its platform offers a range of functionalities, such as demand aggregation, forecasting, sourcing, and procurement, while enabling collaboration with n-tier suppliers on the purchase of essential materials like metals and electronic components. By utilizing a proprietary data conversion process and a unique metals price benchmarking solution, Supply Dynamics helps manufacturers recover value across the extended supply chain, understand material needs, and mitigate price volatility, ultimately improving efficiency and reducing costs.

3Bar Biologics

Series A in 2017
3Bar Biologics Inc. is a Columbus, Ohio-based bioscience company that specializes in developing sustainable agricultural solutions. Established in 2013, the company focuses on enhancing crop yields through its flagship product, Bio-YIELD, a microbe inoculant system. Bio-YIELD utilizes naturally occurring microbes specifically matched to various crops and soil environments, promoting healthier plant growth without the need for synthetic chemicals. This innovative system was the result of over 15 years of research conducted by scientists at The Ohio State University. Initially launched in 2014 for eastern Corn Belt growers, 3Bar Biologics aims to expand its market reach globally as it gathers additional supporting data, thereby assisting farmers in sustainably increasing yields while protecting their investments in land and seed.

Airway Therapeutics

Convertible Note in 2017
Airway Therapeutics, Inc. is a biopharmaceutical company focused on developing protein therapeutics for lung and pediatric applications. Based in Cincinnati, Ohio, with additional offices in Marietta, Georgia, the company specializes in products like recombinant human surfactant protein-D, aimed at preventing bronchopulmonary dysplasia in premature infants, and AT100, a protein replacement therapy for the same condition. The company licenses technology from the pulmonary research program of Cincinnati Children's Hospital Medical Center, which supports the development of multiple products targeting various lung disorders. Airway Therapeutics aims to address the cycle of injury and inflammation in patients with respiratory and inflammatory diseases through advanced biologics that reduce inflammation, infection, and modulate immune responses, ultimately improving treatment outcomes.

Healthy Roster

Seed Round in 2016
Healthy Roster, Inc. is a technology company that specializes in a virtual athletic training app and injury communication platform designed to enhance the management of sports injuries and facilitate communication among athletic trainers, parents, coaches, and school administrators. Founded in 2015 and based in Dublin, Ohio, the company offers a mobile sports-specific electronic health record (EHR) system that allows athletic trainers to efficiently document, track, and manage injuries. This platform ensures timely notifications regarding injuries or updates, fostering better engagement and coordination among all stakeholders involved in an athlete's care. Healthy Roster’s services are tailored for high schools, middle schools, and youth sports leagues, providing parents with direct access to certified athletic trainers and streamlining communication throughout the recovery process. The company aims to leverage technology to improve the delivery of athletic training services and enhance the overall experience for athletes and their support networks.

NaviStone

Seed Round in 2016
NaviStone is a technology company based in Cincinnati, Ohio, specializing in website visitor and behavior tracking to aid direct marketers in identifying potential customers for direct mail campaigns. Its flagship product, NaviStone Prospecting, enables marketers to connect previously anonymous website visitors with postal addresses, creating a targeted audience based on online browsing behavior that indicates "intent to buy." This technology supports various marketing initiatives, including customer acquisition, reactivation of existing customers, and opportunities for remarketing abandoned carts and browsing. Serving professionals in sectors such as nonprofit, retail, and financial services, NaviStone enhances marketing efficiency and drives growth by leveraging first-party audience data.

Standard Bariatrics

Seed Round in 2016
Standard Bariatrics is a medical device company based in Cincinnati, Ohio, founded in 2014. The company specializes in developing surgical instruments designed specifically for weight-loss surgeries, particularly laparoscopic sleeve gastrectomy. One of its key products, the Standard Clamp, enables surgeons to standardize their techniques, thereby reducing variation and improving efficiency during procedures. The company’s tools are intended to be used alongside general-use endoscopic staplers with reloadable cartridges, which helps to minimize the number of cartridges required for each surgery. This innovation not only lowers costs for healthcare providers but also assists in creating consistent surgical outcomes.

Medacheck

Series A in 2015
MedaCheck LLC, founded in 2012 and based in Cincinnati, Ohio, provides a personalized medication management system tailored for seniors and individuals requiring assistance with their prescriptions. The company's platform consists of three main components: CheckBox, a hardware device that enhances patient adherence; Pillbox, a communication software that supports and reminds patients about their medications; and CheckIn, a tool that fosters connectivity between patients, healthcare professionals, and caregivers. This system helps monitor patients' health status in real-time, ensuring that their medical teams and families are informed and able to assist effectively. MedaCheck serves a variety of clients within the healthcare sector, including telehealth providers, health insurers, and assisted living facilities, all aimed at improving patient outcomes and adherence to prescribed treatments.

Airway Therapeutics

Series A in 2014
Airway Therapeutics, Inc. is a biopharmaceutical company focused on developing protein therapeutics for lung and pediatric applications. Based in Cincinnati, Ohio, with additional offices in Marietta, Georgia, the company specializes in products like recombinant human surfactant protein-D, aimed at preventing bronchopulmonary dysplasia in premature infants, and AT100, a protein replacement therapy for the same condition. The company licenses technology from the pulmonary research program of Cincinnati Children's Hospital Medical Center, which supports the development of multiple products targeting various lung disorders. Airway Therapeutics aims to address the cycle of injury and inflammation in patients with respiratory and inflammatory diseases through advanced biologics that reduce inflammation, infection, and modulate immune responses, ultimately improving treatment outcomes.

nChannel

Series A in 2013
nChannel, Inc. is a provider of a cloud-based multichannel management software that enables merchants to sell products across various online and offline channels. Founded in 2011 and based in Columbus, Ohio, the company offers a comprehensive platform that integrates product information management, order management, inventory synchronization, and supply chain processes. This solution allows businesses to connect their existing financial, ERP, and POS systems with multiple sales channels, including popular platforms like Amazon and Shopify. By streamlining operations and improving data visibility, nChannel helps merchants enhance their overall shopping experience and manage their sales processes more efficiently. The platform serves a diverse range of industries, including outdoor and sporting goods, consumer goods, apparel, and non-profit sectors, catering to merchants of various sizes.

Ischemia Care

Venture Round in 2013
Ischemia Care, LLC is a molecular diagnostic company based in Oxford, Ohio, specializing in blood tests designed to aid physicians in diagnosing the causes of ischemic strokes and transient ischemic attacks. The company offers a range of diagnostic services, including ISCDx, a test that employs gene expression analysis to identify stroke causes, and various laboratory tests performed in hospital settings. Its products, such as the ER Stroke Triage Test, support emergency room clinicians in confirming strokes quickly. By utilizing blood testing as a clinical workflow tool, Ischemia Care aims to improve patient outcomes and reduce healthcare costs by ensuring patients receive appropriate treatment pathways to prevent recurrence. Established in 2002, the company was formerly known as Gerard Ventures, LLC, before rebranding in 2011.

Neuros Medical

Series B in 2012
Neuros Medical, Inc. is a neuromodulation company based in Willoughby Hills, Ohio, that specializes in developing proprietary neurostimulation therapies aimed at addressing unmet medical needs for patients globally. The company's flagship technology, known as Electrical Nerve Block, targets chronic pain conditions, including neuroma and residual limb pain, chronic post-surgical pain, and chronic migraine. Neuros Medical also offers the Neuros Altius System, which features an implantable generator with an integrated rechargeable battery, a cuff electrode, and associated external devices. Established in 2008, the company is dedicated to advancing innovative solutions for pain management.

Define My Style

Seed Round in 2011
Define My Style, Inc. is an online platform that enables individuals to design custom handbags and engage in social commerce. Founded in 2011 and based in Cincinnati, Ohio, the company fosters creativity and collaboration among its community of over 50,000 members, primarily young women. Participants can take on various roles such as buyer, designer, marketer, critic, or influencer, allowing them to actively contribute to the fashion ecosystem. In addition to facilitating design and idea sharing, Define My Style also produces and sells a range of handbags, including mini, tote, messenger, overnight, and shopping bags, along with accessories. The platform emphasizes inspiration and connection, providing users with the tools and networks necessary to turn their design ideas into reality.

Ischemia Care

Series B in 2011
Ischemia Care, LLC is a molecular diagnostic company based in Oxford, Ohio, specializing in blood tests designed to aid physicians in diagnosing the causes of ischemic strokes and transient ischemic attacks. The company offers a range of diagnostic services, including ISCDx, a test that employs gene expression analysis to identify stroke causes, and various laboratory tests performed in hospital settings. Its products, such as the ER Stroke Triage Test, support emergency room clinicians in confirming strokes quickly. By utilizing blood testing as a clinical workflow tool, Ischemia Care aims to improve patient outcomes and reduce healthcare costs by ensuring patients receive appropriate treatment pathways to prevent recurrence. Established in 2002, the company was formerly known as Gerard Ventures, LLC, before rebranding in 2011.

EndoSphere

Series A in 2011
EndoSphere is a developer of innovative, non-invasive devices aimed at treating gastrointestinal disorders and metabolic diseases, including obesity, non-alcoholic fatty liver disease, and type 2 diabetes. Founded in 2006 and headquartered in Columbus, Ohio, the company focuses on endoscopic therapies that leverage the body's natural physiology to facilitate safe and effective weight loss without the necessity for surgery or medication. By targeting obesity and its associated health conditions, EndoSphere's approach offers a promising alternative for patients seeking to improve their health outcomes through non-surgical means.

Transactiv

Series A in 2009
Transactiv is a new Cincinnati-based startup dedicated to enabling online commerce for businesses of all sizes. Founded by a team of experienced professionals from SAP, Microsoft, and i2, Transactiv addresses a fundamental need in online commerce to effectively connect millions of products and businesses online.
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