Purdue Research Foundation

Adipo Therapeutics is a biotechnology company focused on developing polymer-based nanotherapeutics aimed at treating obesity and type 2 diabetes. The company employs an innovative approach that utilizes notch-inhibiting nanoparticles, which are administered through weekly self-injections into subcutaneous white adipose tissue. These nanoparticles promote the conversion of energy-storing white fat cells into energy-burning brown fat cells, resulting in significant systemic metabolic changes. This transformation leads to increased energy expenditure, reduced body weight, and improved insulin sensitivity, thereby helping individuals achieve natural weight loss and restore metabolic balance. Adipo Therapeutics aims to positively impact the lives of millions affected by obesity-related diseases.

OmniVis is a biotechnology company that has created an integrated portable platform for the detection of pathogens in various environments, including food processing facilities. The company offers a handheld device that quantitatively measures pathogens, providing accurate results in under 30 minutes. This technology utilizes single-use disposable test kits that analyze swabs or liquid samples, significantly reducing the time and labor associated with traditional lab testing. By delivering a low-cost and user-friendly solution, OmniVis enables health organizations to enhance their pathogen detection capabilities effectively.

Novosteo Inc., founded in 2017 and located in West Lafayette, Indiana, focuses on developing and manufacturing innovative drugs aimed at treating bone injuries and diseases. The company addresses significant health issues related to bone fractures, including morbidity, mortality, and reduced mobility and productivity. Its scientific co-founders from Purdue University have pioneered a proprietary chemistry approach that targets bone regeneration. Novosteo's drug discovery platform features a range of fracture-targeted therapeutics designed to deliver healing agents directly to fracture sites, enhancing the healing process and alleviating the debilitating effects associated with bone injuries. Through its novel biologics, Novosteo aims to improve patient outcomes and quality of life.

ClearBlade, Inc. is an Edge Computing software company that specializes in enabling enterprises to develop and operate secure, real-time, and scalable Internet of Things (IoT) applications. Founded in 2007 and headquartered in Austin, Texas, with an additional office in Raleigh, North Carolina, ClearBlade's platform is designed to function across cloud, on-premise, and edge environments. The company's suite of products includes tools for mobile application management, real-time data processing, and analytics, all of which support industries such as rail, mining, healthcare, and smart cities. Key offerings include ClearConcert for task management, ClearMonitor for job queue management, and the ClearBlade Edge, which delivers powerful processing capabilities directly to devices while ensuring system resilience and security. ClearBlade's solutions allow businesses to ingest, analyze, and act on data efficiently, integrating seamlessly with existing enterprise systems and providing a consistent platform for managing IoT systems.

Animated Dynamics, Inc. specializes in the development and commercialization of live-tissue imaging technologies aimed at enhancing drug assessment in the life and health sciences. The company's core offering, BioDynamic Imaging, utilizes low-coherence digital holography to analyze cellular motions within three-dimensional living tissue samples. This innovative approach allows for a more comprehensive understanding of drug responses compared to traditional two-dimensional methods. By providing insights into cellular mechanisms of action, the technology enables researchers to map phenotypic responses in tumor tissues and assess drug effects in various tissue environments. Established in 2011 and headquartered in West Lafayette, Indiana, Animated Dynamics is committed to advancing the field of drug assessment through its cutting-edge imaging solutions.

Confluence Pharmaceuticals is developing novel therapeutic medications for neurological development disorders. The company's current focus is advancing a novel drug discovery that improves social and communication impairments for individuals with Autism Spectrum Disorders and Fragile X Syndrome.

Novosteo Inc., founded in 2017 and located in West Lafayette, Indiana, focuses on developing and manufacturing innovative drugs aimed at treating bone injuries and diseases. The company addresses significant health issues related to bone fractures, including morbidity, mortality, and reduced mobility and productivity. Its scientific co-founders from Purdue University have pioneered a proprietary chemistry approach that targets bone regeneration. Novosteo's drug discovery platform features a range of fracture-targeted therapeutics designed to deliver healing agents directly to fracture sites, enhancing the healing process and alleviating the debilitating effects associated with bone injuries. Through its novel biologics, Novosteo aims to improve patient outcomes and quality of life.

Brightlamp is a computational medicine company that produces consumer ready software for medical diagnostics. It focuses on medical mobility by using software based applications on mobile devices to diagnose symptoms. The company is on a mission to make the world medically mobile by reforming the way people interact with technology and their health. Brightlamp was founded in 2015 and is headquartered in West Lafayette, Indiana.

Animated Dynamics, Inc. specializes in the development and commercialization of live-tissue imaging technologies aimed at enhancing drug assessment in the life and health sciences. The company's core offering, BioDynamic Imaging, utilizes low-coherence digital holography to analyze cellular motions within three-dimensional living tissue samples. This innovative approach allows for a more comprehensive understanding of drug responses compared to traditional two-dimensional methods. By providing insights into cellular mechanisms of action, the technology enables researchers to map phenotypic responses in tumor tissues and assess drug effects in various tissue environments. Established in 2011 and headquartered in West Lafayette, Indiana, Animated Dynamics is committed to advancing the field of drug assessment through its cutting-edge imaging solutions.

SPEAK MODalities, LLC is a company that specializes in software solutions aimed at enhancing language skills in children with autism and speech development delays. Founded in 2013 and located in West Lafayette, Indiana, the company offers SPEAKall!, a tablet and iPad application specifically tailored for children with autism spectrum and developmental disorders. This app is designed to foster natural speech and language development while also promoting social interaction and engagement through culturally relevant content. By providing evidence-based tools, SPEAK MODalities aims to support children in improving their communication skills and language concepts.

Animated Dynamics, Inc. specializes in the development and commercialization of live-tissue imaging technologies aimed at enhancing drug assessment in the life and health sciences. The company's core offering, BioDynamic Imaging, utilizes low-coherence digital holography to analyze cellular motions within three-dimensional living tissue samples. This innovative approach allows for a more comprehensive understanding of drug responses compared to traditional two-dimensional methods. By providing insights into cellular mechanisms of action, the technology enables researchers to map phenotypic responses in tumor tissues and assess drug effects in various tissue environments. Established in 2011 and headquartered in West Lafayette, Indiana, Animated Dynamics is committed to advancing the field of drug assessment through its cutting-edge imaging solutions.

Microfluidic Innovations LLC specializes in the design, development, and production of programmable lab-on-a-chip systems aimed at enhancing research productivity for life scientists. Founded in 2009 and based in West Lafayette, Indiana, the company offers the AssayMark System, which allows users to develop assays without the complexities of microfluidic chip design and fabrication. Their software-programmable lab-on-a-chip platform facilitates the creation of new microfluidic assays applicable in drug discovery, genomics, proteomics, and cell-based research. This innovative technology enables researchers to conduct experiments at a microfluidic scale, providing precision and automation that significantly improve the efficiency of life science assays. Microfluidic Innovations caters to various sectors, including drug discovery, clinical diagnostics, biochemistry, and cell biology.

Perfinity Biosciences, Inc. focuses on developing tools for protein sample preparation, offering a range of products designed to enhance reproducibility and efficiency. Its product portfolio includes immobilized enzymes, affinity reagents, optimized buffers, and software solutions. Notable offerings include Soluble Smart Digest, a stable soluble trypsin for quick and consistent digestions, and Mag Beads, tailored for proteomics applications. The QuicPrep platform combines immunoaffinity and trypsin digestion in a single process, while Flash Digest provides a rapid and stable immobilized trypsin reactor. Additionally, the Workstation automates protein separations and mass spectrometry sample preparation. Founded in 2004 and based in West Lafayette, Indiana, the company was previously known as QuadraSpec, Inc. until its name change in March 2010.

Perfinity Biosciences, Inc. focuses on developing tools for protein sample preparation, offering a range of products designed to enhance reproducibility and efficiency. Its product portfolio includes immobilized enzymes, affinity reagents, optimized buffers, and software solutions. Notable offerings include Soluble Smart Digest, a stable soluble trypsin for quick and consistent digestions, and Mag Beads, tailored for proteomics applications. The QuicPrep platform combines immunoaffinity and trypsin digestion in a single process, while Flash Digest provides a rapid and stable immobilized trypsin reactor. Additionally, the Workstation automates protein separations and mass spectrometry sample preparation. Founded in 2004 and based in West Lafayette, Indiana, the company was previously known as QuadraSpec, Inc. until its name change in March 2010.