Polaris Partners

Polaris Partners is a venture capital firm based in Boston, Massachusetts, with offices in San Francisco. Founded in 1996, it targets investments in technology and life science companies across the United States and Europe, supporting startups from early formation to profitable growth. The firm's healthcare and biotechnology focus encompasses digital health, consumer-centric care delivery, patient-provider solutions, data science and analytics, as well as therapeutics, genomics and other life science platforms. It backs companies across business-to-business and business-to-consumer models, software as a service, healthcare information technology and health tech sectors, partnering with repeat entrepreneurs to build durable, scale-ready businesses.

David Barrett

Managing Partner

Marissa Bertorelli

Principal

Alexandra Cantley Ph.D

Partner

Darren Carroll

Partner

Brian Chee

Managing Partner

Past deals in Personal Health

FIRE1

Venture Round in 2025
FIRE1 is an Irish-based company specializing in the development of innovative therapeutic devices. Its flagship product is a remote monitoring system designed to enhance heart failure patients' lives by providing real-time data to healthcare providers, facilitating early detection and proactive interventions.

Nomad Health

Series E in 2024
Nomad Health, Inc. is an online marketplace that connects clinicians with freelance and permanent clinical job opportunities in the United States. Founded in 2015 and based in New York, the company provides a platform where doctors and nurses can search for employment based on various criteria such as location, pay rate, and medical specialty. Nomad Health aims to streamline the healthcare staffing process by replacing traditional methods with a modern, efficient technology platform. The service not only simplifies job searches but also manages digital resumes and credentials, facilitating communication between clinicians and healthcare facilities. This innovative approach addresses the complexities of healthcare staffing, enhancing the experience for both job seekers and providers.

Livara Health

Series B in 2024
Livara Health specializes in non-invasive, personalized treatment for musculoskeletal conditions. Its platform offers a data-driven six-week program for back pain relief, customized based on patient assessment, along with coaching support.

Folx Health

Series B in 2022
Folx Health is a Boston-based telehealth platform founded in 2020, specializing in digital healthcare services tailored for the LGBTQIA+ community. It offers access to queer and trans clinicians, focusing on gender-affirming hormone therapy, sexual health, and family creation services.

Nomad Health

Venture Round in 2022
Nomad Health, Inc. is an online marketplace that connects clinicians with freelance and permanent clinical job opportunities in the United States. Founded in 2015 and based in New York, the company provides a platform where doctors and nurses can search for employment based on various criteria such as location, pay rate, and medical specialty. Nomad Health aims to streamline the healthcare staffing process by replacing traditional methods with a modern, efficient technology platform. The service not only simplifies job searches but also manages digital resumes and credentials, facilitating communication between clinicians and healthcare facilities. This innovative approach addresses the complexities of healthcare staffing, enhancing the experience for both job seekers and providers.

Kallyope

Series D in 2022
Kallyope Inc. is a biotechnology company based in New York City that focuses on understanding the gut-brain axis to develop innovative therapeutics and consumer products aimed at enhancing human health. Established in 2014, Kallyope employs advanced technologies, including sequencing, computational biology, neural imaging, and human genetics, to explore gut-brain biology. The company aims to address significant unmet medical needs, such as diabetes, obesity, gut disorders, inflammatory diseases, migraines, and allergies, by creating effective and user-friendly oral agents. Kallyope's team consists of experienced scientists from leading institutions, working alongside a skilled team with a strong track record in drug discovery and development. Through its research, Kallyope seeks to deliver transformative solutions that improve overall health outcomes.

Nomad Health

Series D in 2021
Nomad Health, Inc. is an online marketplace that connects clinicians with freelance and permanent clinical job opportunities in the United States. Founded in 2015 and based in New York, the company provides a platform where doctors and nurses can search for employment based on various criteria such as location, pay rate, and medical specialty. Nomad Health aims to streamline the healthcare staffing process by replacing traditional methods with a modern, efficient technology platform. The service not only simplifies job searches but also manages digital resumes and credentials, facilitating communication between clinicians and healthcare facilities. This innovative approach addresses the complexities of healthcare staffing, enhancing the experience for both job seekers and providers.

Wellthy

Series B in 2021
Wellthy, Inc. is a family care concierge service based in New York, established in 2014. The company specializes in assisting individuals and families managing complex care situations, particularly those involving chronic illnesses, aging-related issues, or disabilities. Wellthy connects families with dedicated Care Coordinators who help navigate the logistical and administrative challenges of caregiving. This includes organizing appointments, managing contacts, and storing essential documents. The service is designed to support families dealing with a range of health conditions, such as dementia, diabetes, heart disease, and cancer, as well as those requiring assistance with childcare and special needs. Through its platform, Wellthy aims to alleviate the burden of care management, allowing families to focus on their loved ones’ well-being.

Thirty Madison

Series C in 2021
Thirty Madison is a digital health company specializing in personalized treatments for chronic conditions. It operates platforms like Keeps (hair loss), Cove (migraines), Picnic (allergies), Facet (skin conditions), and Nurx (sexual health). Founded in 2016, it aims to empower individuals with accessible, effective care tailored to their specific needs.

Livara Health

Series A in 2021
Livara Health specializes in non-invasive, personalized treatment for musculoskeletal conditions. Its platform offers a data-driven six-week program for back pain relief, customized based on patient assessment, along with coaching support.

Folx Health

Series A in 2021
Folx Health is a Boston-based telehealth platform founded in 2020, specializing in digital healthcare services tailored for the LGBTQIA+ community. It offers access to queer and trans clinicians, focusing on gender-affirming hormone therapy, sexual health, and family creation services.

Thirty Madison

Series B in 2020
Thirty Madison is a digital health company specializing in personalized treatments for chronic conditions. It operates platforms like Keeps (hair loss), Cove (migraines), Picnic (allergies), Facet (skin conditions), and Nurx (sexual health). Founded in 2016, it aims to empower individuals with accessible, effective care tailored to their specific needs.

Folx Health

Venture Round in 2020
Folx Health is a Boston-based telehealth platform founded in 2020, specializing in digital healthcare services tailored for the LGBTQIA+ community. It offers access to queer and trans clinicians, focusing on gender-affirming hormone therapy, sexual health, and family creation services.

Kallyope

Series C in 2020
Kallyope Inc. is a biotechnology company based in New York City that focuses on understanding the gut-brain axis to develop innovative therapeutics and consumer products aimed at enhancing human health. Established in 2014, Kallyope employs advanced technologies, including sequencing, computational biology, neural imaging, and human genetics, to explore gut-brain biology. The company aims to address significant unmet medical needs, such as diabetes, obesity, gut disorders, inflammatory diseases, migraines, and allergies, by creating effective and user-friendly oral agents. Kallyope's team consists of experienced scientists from leading institutions, working alongside a skilled team with a strong track record in drug discovery and development. Through its research, Kallyope seeks to deliver transformative solutions that improve overall health outcomes.

Nomad Health

Series C in 2019
Nomad Health, Inc. is an online marketplace that connects clinicians with freelance and permanent clinical job opportunities in the United States. Founded in 2015 and based in New York, the company provides a platform where doctors and nurses can search for employment based on various criteria such as location, pay rate, and medical specialty. Nomad Health aims to streamline the healthcare staffing process by replacing traditional methods with a modern, efficient technology platform. The service not only simplifies job searches but also manages digital resumes and credentials, facilitating communication between clinicians and healthcare facilities. This innovative approach addresses the complexities of healthcare staffing, enhancing the experience for both job seekers and providers.

Wellthy

Series A in 2019
Wellthy, Inc. is a family care concierge service based in New York, established in 2014. The company specializes in assisting individuals and families managing complex care situations, particularly those involving chronic illnesses, aging-related issues, or disabilities. Wellthy connects families with dedicated Care Coordinators who help navigate the logistical and administrative challenges of caregiving. This includes organizing appointments, managing contacts, and storing essential documents. The service is designed to support families dealing with a range of health conditions, such as dementia, diabetes, heart disease, and cancer, as well as those requiring assistance with childcare and special needs. Through its platform, Wellthy aims to alleviate the burden of care management, allowing families to focus on their loved ones’ well-being.

Kallyope

Series B in 2018
Kallyope Inc. is a biotechnology company based in New York City that focuses on understanding the gut-brain axis to develop innovative therapeutics and consumer products aimed at enhancing human health. Established in 2014, Kallyope employs advanced technologies, including sequencing, computational biology, neural imaging, and human genetics, to explore gut-brain biology. The company aims to address significant unmet medical needs, such as diabetes, obesity, gut disorders, inflammatory diseases, migraines, and allergies, by creating effective and user-friendly oral agents. Kallyope's team consists of experienced scientists from leading institutions, working alongside a skilled team with a strong track record in drug discovery and development. Through its research, Kallyope seeks to deliver transformative solutions that improve overall health outcomes.

Nomad Health

Series B in 2018
Nomad Health, Inc. is an online marketplace that connects clinicians with freelance and permanent clinical job opportunities in the United States. Founded in 2015 and based in New York, the company provides a platform where doctors and nurses can search for employment based on various criteria such as location, pay rate, and medical specialty. Nomad Health aims to streamline the healthcare staffing process by replacing traditional methods with a modern, efficient technology platform. The service not only simplifies job searches but also manages digital resumes and credentials, facilitating communication between clinicians and healthcare facilities. This innovative approach addresses the complexities of healthcare staffing, enhancing the experience for both job seekers and providers.

Kallyope

Series B in 2018
Kallyope Inc. is a biotechnology company based in New York City that focuses on understanding the gut-brain axis to develop innovative therapeutics and consumer products aimed at enhancing human health. Established in 2014, Kallyope employs advanced technologies, including sequencing, computational biology, neural imaging, and human genetics, to explore gut-brain biology. The company aims to address significant unmet medical needs, such as diabetes, obesity, gut disorders, inflammatory diseases, migraines, and allergies, by creating effective and user-friendly oral agents. Kallyope's team consists of experienced scientists from leading institutions, working alongside a skilled team with a strong track record in drug discovery and development. Through its research, Kallyope seeks to deliver transformative solutions that improve overall health outcomes.

Kallyope

Series A in 2015
Kallyope Inc. is a biotechnology company based in New York City that focuses on understanding the gut-brain axis to develop innovative therapeutics and consumer products aimed at enhancing human health. Established in 2014, Kallyope employs advanced technologies, including sequencing, computational biology, neural imaging, and human genetics, to explore gut-brain biology. The company aims to address significant unmet medical needs, such as diabetes, obesity, gut disorders, inflammatory diseases, migraines, and allergies, by creating effective and user-friendly oral agents. Kallyope's team consists of experienced scientists from leading institutions, working alongside a skilled team with a strong track record in drug discovery and development. Through its research, Kallyope seeks to deliver transformative solutions that improve overall health outcomes.

Arivale

Series B in 2015
Arivale Inc. is a wellness services provider that focuses on helping individuals optimize their health and prevent diseases through a scientific approach. Founded in 2014 and headquartered in Seattle, Washington, the company analyzes various aspects of an individual's health, including genetics, blood markers, microbiome data, and lifestyle choices. By combining this personalized data with tailored coaching and support from a clinical team, Arivale delivers actionable recommendations to enhance wellness. Their program not only empowers individuals to make informed decisions regarding diet and exercise but also contributes to a longitudinal dataset that aids in the discovery of innovative health improvement methods. Overall, Arivale is dedicated to providing a comprehensive and intimate view of well-being to enhance the quality of life for its members.

First Opinion

Series A in 2014
First Opinion, established in 2013 and headquartered in San Francisco, specializes in a smartphone-based application that connects parents, primarily mothers, with physician mothers for health-related advice and support. This includes guidance on illness, injury, pregnancy, child development, nutrition, lactation, and sleep training. The platform offers 24/7 access to doctors via messaging, with the option to upgrade for treatment services.

EXOS

Venture Round in 2012
EXOS, Inc. is a human performance company based in Phoenix, Arizona, with additional facilities in Los Angeles, San Diego, Frisco, Miami, and Charlotte. Founded in 1999, EXOS specializes in training, nutrition, physical therapy, and consulting services tailored for professional athletes, as well as individuals and organizations in various sectors. The company offers a wide range of services, including facility design and management, performance assessments, rehabilitation, and wellness programs. With a focus on evidence-based strategies, EXOS has developed integrated solutions for workplace wellness, serving corporate campuses, military bases, health clubs, academic institutions, and sports organizations. Formerly known as Athletes' Performance, Inc., the company rebranded to EXOS in January 2014 and has established itself as a leader in performance training and physical therapy worldwide.

Ella Health

Seed Round in 2011
Ella Health is a women's wellness provider headquartered in San Francisco, California, with multiple centers across the United States. The company focuses on delivering healthcare services tailored specifically for women, including advanced 3D mammography, which enhances cancer detection and minimizes false positives compared to traditional 2D imaging. Additionally, Ella Health offers physical therapy programs designed to address the unique needs of women at various stages of life. By combining innovative technology with compassionate care and aesthetically pleasing environments, Ella Health aims to create a welcoming atmosphere that helps women feel more comfortable and empowered in managing their health.

Free & Clear

Venture Round in 2010
Free & Clear, Inc. specializes in providing phone-based tobacco treatment services to employers, health plans, and government agencies. The company offers comprehensive tobacco cessation programs, including the Quit For Life Program, which is designed to help employees and members of private organizations quit smoking and using smokeless tobacco through clinically proven methods. In addition, Free & Clear addresses broader health risks associated with chronic diseases by offering the Mind & Body Program, a behavior change solution aimed at helping individuals achieve and maintain a healthy weight. Through these services, Free & Clear aims to promote healthier lifestyles and reduce the impact of tobacco use on public health.

HealthCentral

Post in 2008
HealthCentral operates a digital health platform dedicated to empowering patients and caregivers. It provides comprehensive information and tools related to consumer health and wellness through authentic communities and research-based education, enabling users to make informed decisions about their health.

EXOS

Series B in 2007
EXOS, Inc. is a human performance company based in Phoenix, Arizona, with additional facilities in Los Angeles, San Diego, Frisco, Miami, and Charlotte. Founded in 1999, EXOS specializes in training, nutrition, physical therapy, and consulting services tailored for professional athletes, as well as individuals and organizations in various sectors. The company offers a wide range of services, including facility design and management, performance assessments, rehabilitation, and wellness programs. With a focus on evidence-based strategies, EXOS has developed integrated solutions for workplace wellness, serving corporate campuses, military bases, health clubs, academic institutions, and sports organizations. Formerly known as Athletes' Performance, Inc., the company rebranded to EXOS in January 2014 and has established itself as a leader in performance training and physical therapy worldwide.

Ascend Health

Series B in 2007
Ascend Health Corporation is a healthcare provider specialising in behavioural health. It operates inpatient and day hospital facilities offering personalised care for children, adolescents, adults, and seniors. Ascend focuses on integrating its services with local community healthcare systems to deliver high-quality mental health and chemical dependency treatments.

EXOS

Series A in 2006
EXOS, Inc. is a human performance company based in Phoenix, Arizona, with additional facilities in Los Angeles, San Diego, Frisco, Miami, and Charlotte. Founded in 1999, EXOS specializes in training, nutrition, physical therapy, and consulting services tailored for professional athletes, as well as individuals and organizations in various sectors. The company offers a wide range of services, including facility design and management, performance assessments, rehabilitation, and wellness programs. With a focus on evidence-based strategies, EXOS has developed integrated solutions for workplace wellness, serving corporate campuses, military bases, health clubs, academic institutions, and sports organizations. Formerly known as Athletes' Performance, Inc., the company rebranded to EXOS in January 2014 and has established itself as a leader in performance training and physical therapy worldwide.
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