Playground Global

Synthetic Design Lab is a therapeutics developer based in Burlingame, California, focused on enhancing the delivery of targeted payloads in antibody-drug conjugates (ADCs). The company's innovative platform is designed to optimize payload delivery by a factor of ten compared to existing ADCs. This advancement aims to improve the efficacy, safety, and overall versatility of these therapeutic agents. Currently, Synthetic Design Lab is operating in stealth mode, indicating a commitment to discreetly advancing its technology before broader market engagement.

GigaCrop reinvents photosynthesis to power greater harvests.

NVision Imaging Technologies GmbH, founded in 2015 and based in Ulm, Germany, specializes in the development and commercialization of innovative imaging and sensing applications grounded in quantum physics. The company has created a platform that polarizes natural metabolites, enabling their use as agents for imaging tumor metabolism through magnetic resonance imaging (MRI). This technology transforms standard magnetic resonance spectrometers into tools capable of assessing human metabolism, thereby enhancing the precision of cancer diagnostics and facilitating real-time monitoring of patient responses to therapy. By leveraging advances in quantum physics, NVision aims to make significant strides in the medical imaging and diagnostics sector.

Ayar Labs, Inc. specializes in the development of optical interconnect technology, focusing on high-density electronic-photonic chiplets and lasers designed to enhance data transmission capabilities. Its flagship product, TeraPHY, is a monolithic in-package optical I/O solution that enables high bandwidth, low latency, and power-efficient short-reach interconnects, making it suitable for applications in artificial intelligence, high-performance computing, cloud computing, telecommunications, and aerospace. The company's innovative approach leverages industry-standard silicon processing techniques to create optical interconnect chiplets that replace traditional electrical-based I/O, addressing performance and efficiency challenges in the semiconductor and computing industries. By optimizing data movement within AI systems, Ayar Labs aims to alleviate compute and bandwidth bottlenecks associated with complex large language models, thereby maximizing computational efficiency while minimizing costs and power consumption. Established in 2015 and headquartered in Emeryville, California, Ayar Labs also has an office in Santa Clara, California.

Anjuna is a developer of a cloud security platform that provides hardware-grade protection for data, applications, and workloads in the public cloud. The company's technology enables enterprises to securely run their most sensitive workloads by leveraging advanced hardware-based secure computing technologies. Unlike traditional perimeter security solutions, which are often vulnerable to insider threats and malicious code, Anjuna's platform offers seamless end-to-end encryption through secure enclaves. This approach ensures that applications and data remain protected from unauthorized access, making the public cloud a safe computing resource for businesses.

Outpace Bio is a biotechnology company that creates smart cell therapies aimed at improving efficacy and safety. It offers a platform that combines custom-designed biological functions with cellular control modalities that program the right response at the right time and place. It creates a mechanism-driven solution tailor-made to improve efficacy and safety. The company collaborates with Lyell Immunopharma to develop and commercialize a potential immune cell therapy for the treatment of cancer, auto-immune diseases, infectious diseases, degenerative diseases, regenerative medicine, metabolic disorders, and genetic disorders, enabling healthcare providers to cure a wide range of diseases as per patient's need.

Pandion has developed a logistics technology platform designed to assist e-commerce businesses in managing capacity challenges during peak periods. Its delivery management software leverages machine learning to optimize delivery networks and minimize shipping delays, allowing retailers of all sizes to offer one and two-day shipping. By providing affordable and efficient shipping services, Pandion enables companies to enhance customer satisfaction through faster and more reliable deliveries.

Insamo is a biotechnology company focused on the discovery and development of membrane-permeable and orally available cyclic peptides, which possess antibody-like binding affinity. Utilizing an automated platform that integrates molecular biology and parallel synthetic chemistry, Insamo aims to rapidly identify preclinical candidates with favorable pharmacological properties. This innovative approach enables the potential replacement of traditional injected or infused biologics with more accessible oral formulations, thereby enhancing patient care. The company's automated design, synthesis, and testing processes allow for unprecedented scalability in the discovery of these therapeutic compounds.

Element Zero is focused on transforming the processing of metal ores, including iron and nickel, into pure metals through a low-temperature mineral processing platform. This innovative approach aims to enhance the economics of steel production while significantly reducing energy consumption and achieving zero carbon emissions. By utilizing this technology, Element Zero enables businesses to lower their carbon footprint, contributing to more sustainable industrial practices. The company's commitment to efficient and environmentally friendly metal conversion positions it as a key player in the transition toward greener manufacturing processes.

Boxbot is a technology company based in Alameda, California, specializing in parcel logistics automation. Its proprietary software and hardware platform enhances package handling by transforming traditional conveyors into three-dimensional systems. This modular solution allows for the efficient storage, sorting, and sequencing of various package sizes while occupying a minimal physical footprint. By integrating robotics and automated systems, Boxbot addresses key operational challenges in last-mile logistics, facilitating faster and more efficient routing of packages within warehouses. The company's innovations aim to reduce costs associated with last-mile delivery, ultimately improving the overall experience for both suppliers and consumers.

D-Matrix is a technology company focused on developing a computing platform aimed at enhancing artificial intelligence inferencing workloads in data centers. The company is dedicated to creating an innovative, brain-inspired AI compute engine that addresses a wide range of inferencing tasks within the growing cloud and edge infrastructure markets. By employing an in-memory computing approach, D-Matrix seeks to improve the efficiency of memory-compute integration through advanced mixed-signal and digital signal processing techniques. This platform is particularly designed to support generative artificial intelligence applications and large language models, thereby providing clients with enhanced computational capabilities.

Phasecraft is a UK-based company founded in 2018 that develops quantum software aimed at enhancing the practical application of quantum computing. The firm focuses on creating algorithms for quantum information processors, including intermediate-scale devices and quantum computers. By leveraging its expertise in quantum science and engineering, Phasecraft addresses significant industrial challenges, such as optimizing key processes and exploring new materials. The company's software supports clients in investigating innovative quantum materials and developing advanced technologies, including batteries and efficient solar cells. Through its work, Phasecraft aims to facilitate breakthrough scientific discoveries and enable entrepreneurs to tackle pressing global issues more effectively.

Amber Bio is a biotechnology company pioneering new gene editing modalities using multi-kilobase edits to reach previously undruggable patient populations.

NVision Imaging Technologies GmbH, founded in 2015 and based in Ulm, Germany, specializes in the development and commercialization of innovative imaging and sensing applications grounded in quantum physics. The company has created a platform that polarizes natural metabolites, enabling their use as agents for imaging tumor metabolism through magnetic resonance imaging (MRI). This technology transforms standard magnetic resonance spectrometers into tools capable of assessing human metabolism, thereby enhancing the precision of cancer diagnostics and facilitating real-time monitoring of patient responses to therapy. By leveraging advances in quantum physics, NVision aims to make significant strides in the medical imaging and diagnostics sector.

Robust.AI, founded by Anthony Jules in 2019 and based in San Carlos, California, develops advanced solutions that combine artificial intelligence, robotics, and human-centered design. The company has introduced its software suite, Grace, and a concept for a hardware product, Carter, aimed at enhancing interaction between humans and robots. These innovations target the warehousing industry, where a significant majority of operations remain unautomated, exacerbated by ongoing labor shortages in the global supply chain. Robust.AI's cognitive platform focuses on creating collaborative mobile robots that are context-aware, safe, and easy to implement, aiming to make robotics solutions more accessible across various sectors. By emphasizing common-sense AI and hybrid technology, the company seeks to address the challenges of robotics deployment and improve operational efficiency.

Outpace Bio is a biotechnology company that creates smart cell therapies aimed at improving efficacy and safety. It offers a platform that combines custom-designed biological functions with cellular control modalities that program the right response at the right time and place. It creates a mechanism-driven solution tailor-made to improve efficacy and safety. The company collaborates with Lyell Immunopharma to develop and commercialize a potential immune cell therapy for the treatment of cancer, auto-immune diseases, infectious diseases, degenerative diseases, regenerative medicine, metabolic disorders, and genetic disorders, enabling healthcare providers to cure a wide range of diseases as per patient's need.

Atomic AI is focused on advancing RNA drug discovery through the integration of machine learning and structural biology. The company operates a content intelligence platform that facilitates the rational design of new molecules and medicines. By leveraging engagement data from clients' analytics, Atomic AI gathers insights to create predictive reports on various topics, including optimal publishing times and distribution channels. This approach equips users with innovative strategies to develop treatments or cures for diseases by specifically targeting RNA structures.

Saltbox, Inc. is a provider of co-working and co-warehousing rental services, catering to importers, exporters, distributors, and e-commerce operators. Founded in 2019 and headquartered in Atlanta, Georgia, the company offers flexible office spaces and private warehouse suites designed to support small businesses. Its facilities include essential amenities such as Wi-Fi, loading docks, warehouse equipment, conference rooms, and common areas, along with specialized features like temperature-controlled environments and enterprise security. Saltbox aims to foster an entrepreneurial community, enabling clients to efficiently operate, store, and ship goods from a single location.

Strand Therapeutics is a developer of a biotechnology platform intended to create gene therapies powered by synthetic biology.The company's offerings include immunotherapies to help cells produce target cancer-killing proteins during immunotherapy, enabling patients to improve their body's immune system to fight cancer.

Owl Labs Inc. specializes in developing and manufacturing innovative video conferencing technology, aimed at enhancing communication for hybrid and remote teams. Founded in 2014 and based in Somerville, Massachusetts, the company offers a range of products, including the Meeting Owl and Meeting Owl Pro. These smart conference cameras feature 360° views and advanced audio capabilities, allowing them to automatically focus on the speaker during meetings. Owl Labs' products are compatible with popular video conferencing platforms such as Google Hangouts, Skype, and GoToMeeting. The company's mission is to create inclusive and engaging video experiences that facilitate dynamic discussions in modern organizations.

RapidSOS, Inc. is an emergency response data platform that connects life-saving information from over 350 million connected devices directly to 911 and first responders. Founded in 2012 and headquartered in New York, the company serves public safety agencies globally, offering solutions such as the Clearinghouse, which enables users to send emergency requests and receive critical data from devices, and the Emergency API suite for direct data transmission to emergency services. Additionally, the RapidSOS Portal provides public safety agencies with secure access to essential data through a web-based tool. The platform supports more than 4,800 Emergency Communications Centers, protecting over 90% of the U.S. population during approximately 250 million emergencies each year, thereby enhancing the speed and effectiveness of emergency response.

Ideon Technologies Inc. specializes in developing advanced bore-hole detectors and a subsurface intelligence platform for mineral exploration and monitoring. This platform employs cosmic-ray muon tomography, integrating proprietary detectors, imaging systems, inversion technologies, and artificial intelligence to achieve x-ray-like imaging capabilities down to 1 kilometer beneath the Earth's surface. By detecting subsurface muons, Ideon transforms data into reliable geophysical surveys and three-dimensional density maps, allowing exploration geologists to identify, map, and monitor mineral and metal deposits with enhanced precision. The company's innovative approach helps reduce drilling costs and risks, saves time, and minimizes environmental impacts associated with traditional exploration methods. Founded in 2011 and headquartered in Richmond, Canada, Ideon Technologies emerged as a spin-off from TRIUMF, Canada's national particle accelerator laboratory, and was previously known as CRM GeoTomography Technologies, Inc. until its name change in May 2020.

Manifold Bio is a biotechnology company that features a platform that enables multiplexed quantitation of protein therapeutic designs, generating unprecedented data throughout the drug development process to unlock measurement-driven design. The company is building a protein barcoding platform to bring the power of multiplexed measurement to the development of protein therapeutics. It was founded in 2020 and headquartered in Boston, Massachusetts.

FarmWise provides technology-based services that allow farmers to streamline farm operations and increase food production efficiency. It offers a productive mechanical weeding implement for vegetable crops, along with its exceptional training and support program. The company was founded in 2016 and is based in San Francisco, California.

Ultima Genomics is unleashing the power of genomics at scale. Ultima Genomics drives the scale of genomic information to enable unprecedented advances in biology and improvements in human health. The company was founded in 2016 and is based in Newark, California.

Agility Robotic's legged locomotion expertise is built on a history of academic research, including the bipedal walking and running robot ATRIAS. Agility Robotics is leveraging this work to create products that address the real world needs of rugged, efficient, and highly capable mobility platforms.

D-Matrix is a technology company focused on developing a computing platform aimed at enhancing artificial intelligence inferencing workloads in data centers. The company is dedicated to creating an innovative, brain-inspired AI compute engine that addresses a wide range of inferencing tasks within the growing cloud and edge infrastructure markets. By employing an in-memory computing approach, D-Matrix seeks to improve the efficiency of memory-compute integration through advanced mixed-signal and digital signal processing techniques. This platform is particularly designed to support generative artificial intelligence applications and large language models, thereby providing clients with enhanced computational capabilities.

Leaf Logistics Inc. operates a digital freight contracting platform that facilitates a multi-party network connecting shippers, carriers, brokers, and logistics service providers. Founded in 2017 and based in New York, the company specializes in using predictive analytics and artificial intelligence to enhance the management of transportation logistics. Its product suite includes the Leaf Adapt platform, which assists shippers in developing resilient transportation plans, and Leaf Flex forward contracts that ensure value for both shippers and carriers. Through its innovative platform, Leaf Logistics aims to improve service and cost predictability by enabling users to secure future transportation capacity and rates through binding, tradeable contracts.

Mangata is a telecommunication company that specializes in satellite and wired communication services. It was founded in 2020 and is headquartered in Phoenix, Arizona.

RightHand Robotics, Inc. specializes in the manufacturing of robotic order-picking systems designed to enhance supply chain logistics and order fulfillment across various industries, including e-commerce, food handling, and flexible manufacturing. Founded in 2015, the company is headquartered in Cambridge, Massachusetts, with an additional office in Frankfurt, Germany. RightHand Robotics offers innovative solutions like the ReFlex SF, which features a 3D-printed palm equipped with advanced servos and compliant fingers, and the ReFlex TakkTile, a tactile sensor that aids in gentle object handling. Their technology enables robots to automatically grasp a wide range of items from bins and cases without the need for extensive data entry or parameter tuning, making their systems cost-effective and adaptable to changing business needs.

Universal Hydrogen is focused on advancing hydrogen aviation by creating a comprehensive hydrogen ecosystem tailored for the aviation industry. Founded in 2020 and based in Hawthorne, California, the company develops innovative technologies for hydrogen distribution and propulsion. It manufactures capsule modules designed to safely store hydrogen during transit, which also function as modular fuel tanks that can be directly loaded onto aircraft. Universal Hydrogen provides an end-to-end hydrogen value chain, facilitating the transport of hydrogen from production facilities to airports using existing freight infrastructure. This approach eliminates the need for expensive new pipelines and storage facilities, supporting the transition to carbon-free flight and helping to mitigate the climate impact of air travel. Through strategic partnerships and dedicated logistics, Universal Hydrogen aims to make hydrogen-powered aviation a practical reality.

MosaicML specializes in developing software infrastructure and algorithms aimed at enhancing the efficiency of training large language models and neural networks. The company focuses on employing algorithmic techniques, such as sparsity and network pruning, to optimize the training process. By doing so, MosaicML enables users to train large-scale artificial intelligence models more efficiently and cost-effectively within their secure environments, utilizing their proprietary data. This approach not only improves training speed and model quality but also reduces overall costs associated with model development.

Pandion develops a technology platform for e-commerce players to manage capacity problems during peak periods. The logistics platform helps all businesses provide one and two-day shipping, and makes on-time delivery possible for more retailers, regardless of size and scale. Pandion’s delivery management software uses machine learning to avoid shipping delays and optimize delivery networks.

Velo3D, Inc. specializes in additive manufacturing, specifically in the 3D printing of metal components. Founded in 2014 and based in Campbell, California, the company offers an integrated solution that includes the Sapphire Printer, a laser powder bed fusion system designed for support-free metal 3D printing, alongside the Flow print preparation software and the Assure quality assurance system. This innovative approach allows for greater design flexibility by minimizing the need for support structures, enhancing the manufacturing process for industries such as aerospace, energy, and industrial sectors. Velo3D's technology aims to improve performance, reduce costs, and expedite the production timeline of high-value metal parts, ensuring quality and reliability throughout the manufacturing process.

Lacuna Technologies, founded in 2018 by John Ellis in Palo Alto, California, specializes in developing a comprehensive transportation operating system (tOS) that integrates and manages various modes of mobility. The company's software is designed to enhance transportation management for both air and ground travel, utilizing open-source solutions to improve traffic control through detailed reporting, analysis, and modeling of traffic patterns. Lacuna's platform includes digital tools for real-time policy management and data simulators that facilitate the development of analytics tools and exploration of new mobility models. This enables transportation agencies to operate more efficiently and adapt to evolving mobility needs.

Anjuna is a developer of a cloud security platform that provides hardware-grade protection for data, applications, and workloads in the public cloud. The company's technology enables enterprises to securely run their most sensitive workloads by leveraging advanced hardware-based secure computing technologies. Unlike traditional perimeter security solutions, which are often vulnerable to insider threats and malicious code, Anjuna's platform offers seamless end-to-end encryption through secure enclaves. This approach ensures that applications and data remain protected from unauthorized access, making the public cloud a safe computing resource for businesses.

Strand Therapeutics is a developer of a biotechnology platform intended to create gene therapies powered by synthetic biology.The company's offerings include immunotherapies to help cells produce target cancer-killing proteins during immunotherapy, enabling patients to improve their body's immune system to fight cancer.

NextSilicon Ltd. is a technology company based in Tel Aviv-Yafo, Israel, founded in 2018. It specializes in designing and developing advanced computer processing technology that integrates software-defined hardware. The company offers innovative solutions aimed at enhancing high-performance computing (HPC) architectures, addressing fundamental challenges within the industry. By leveraging novel chip designs and software algorithms, NextSilicon enables businesses to accelerate compute-intensive applications, thereby creating opportunities for innovation in supercomputing. Through its unique approach, NextSilicon seeks to advance the future of computing technology.

Artificial, Inc. is a software company specializing in laboratory automation solutions. Founded in 2018 and based in Palo Alto, California, the company has developed a comprehensive platform designed to enhance laboratory operations through automation while maintaining human oversight. Its key products include Flow Scheduler, which facilitates the setup and optimization of lab processes; Flow Tools, offering web-based management of robotic systems; Element SDK, a toolkit for creating robotic automation applications; and Substrate Core, a foundational infrastructure for controlling distributed cyber-physical systems. By providing these innovative tools, Artificial aims to empower scientists and automation engineers to improve productivity and minimize errors in their research and development efforts.

Universal Hydrogen is focused on advancing hydrogen aviation by creating a comprehensive hydrogen ecosystem tailored for the aviation industry. Founded in 2020 and based in Hawthorne, California, the company develops innovative technologies for hydrogen distribution and propulsion. It manufactures capsule modules designed to safely store hydrogen during transit, which also function as modular fuel tanks that can be directly loaded onto aircraft. Universal Hydrogen provides an end-to-end hydrogen value chain, facilitating the transport of hydrogen from production facilities to airports using existing freight infrastructure. This approach eliminates the need for expensive new pipelines and storage facilities, supporting the transition to carbon-free flight and helping to mitigate the climate impact of air travel. Through strategic partnerships and dedicated logistics, Universal Hydrogen aims to make hydrogen-powered aviation a practical reality.

Era Software specializes in observability data management, providing IT and security organizations with tools to efficiently route, ingest, store, and analyze extensive data sets for actionable insights. Their platform, EraSearch, simplifies the management of log data in real-time while significantly reducing costs compared to traditional solutions. As data volumes continue to increase, enterprises often face challenges in determining which data to collect, leading to critical visibility gaps. Era Software addresses these issues by offering a time-series database tailored for machine learning and anomaly detection, thus enhancing performance and scalability in modern application architectures such as cloud, containers, and microservices. This enables users to gain a comprehensive understanding of large data sets with ease.

Saltbox, Inc. is a provider of co-working and co-warehousing rental services, catering to importers, exporters, distributors, and e-commerce operators. Founded in 2019 and headquartered in Atlanta, Georgia, the company offers flexible office spaces and private warehouse suites designed to support small businesses. Its facilities include essential amenities such as Wi-Fi, loading docks, warehouse equipment, conference rooms, and common areas, along with specialized features like temperature-controlled environments and enterprise security. Saltbox aims to foster an entrepreneurial community, enabling clients to efficiently operate, store, and ship goods from a single location.

Outpace Bio is a biotechnology company that creates smart cell therapies aimed at improving efficacy and safety. It offers a platform that combines custom-designed biological functions with cellular control modalities that program the right response at the right time and place. It creates a mechanism-driven solution tailor-made to improve efficacy and safety. The company collaborates with Lyell Immunopharma to develop and commercialize a potential immune cell therapy for the treatment of cancer, auto-immune diseases, infectious diseases, degenerative diseases, regenerative medicine, metabolic disorders, and genetic disorders, enabling healthcare providers to cure a wide range of diseases as per patient's need.

1910 Genetics is a biotechnology company focused on enhancing drug development through the integration of artificial intelligence, computation, and biological automation. By establishing a detailed understanding of the molecular basis of diseases, the company aims to improve the design and discovery of both small and large molecule therapeutics. Its multimodal AI platform, supported by laboratory automation, reimagines traditional drug discovery processes, enabling clients to increase productivity and reduce failure rates in pharmaceutical development.

Pandion has developed a logistics technology platform designed to assist e-commerce businesses in managing capacity challenges during peak periods. Its delivery management software leverages machine learning to optimize delivery networks and minimize shipping delays, allowing retailers of all sizes to offer one and two-day shipping. By providing affordable and efficient shipping services, Pandion enables companies to enhance customer satisfaction through faster and more reliable deliveries.

NVision Imaging Technologies GmbH, founded in 2015 and based in Ulm, Germany, specializes in the development and commercialization of innovative imaging and sensing applications grounded in quantum physics. The company has created a platform that polarizes natural metabolites, enabling their use as agents for imaging tumor metabolism through magnetic resonance imaging (MRI). This technology transforms standard magnetic resonance spectrometers into tools capable of assessing human metabolism, thereby enhancing the precision of cancer diagnostics and facilitating real-time monitoring of patient responses to therapy. By leveraging advances in quantum physics, NVision aims to make significant strides in the medical imaging and diagnostics sector.

Relativity Space is an aerospace company based in Long Beach, California, that designs, develops, and manufactures 3D-printed rockets. Founded in 2015, the company aims to revolutionize rocket production through a vertically integrated technology platform that combines 3D printing, artificial intelligence, and autonomous robotics. This innovative approach allows for a significantly simplified supply chain, enabling the production of rockets with 100 times fewer parts in less than 60 days. In addition to manufacturing rockets, Relativity Space provides comprehensive services for satellite production, testing, and launching. The company is supported by prominent investors, highlighting its potential in the rapidly evolving aerospace sector.

Ayar Labs, Inc. specializes in the development of optical interconnect technology, focusing on high-density electronic-photonic chiplets and lasers designed to enhance data transmission capabilities. Its flagship product, TeraPHY, is a monolithic in-package optical I/O solution that enables high bandwidth, low latency, and power-efficient short-reach interconnects, making it suitable for applications in artificial intelligence, high-performance computing, cloud computing, telecommunications, and aerospace. The company's innovative approach leverages industry-standard silicon processing techniques to create optical interconnect chiplets that replace traditional electrical-based I/O, addressing performance and efficiency challenges in the semiconductor and computing industries. By optimizing data movement within AI systems, Ayar Labs aims to alleviate compute and bandwidth bottlenecks associated with complex large language models, thereby maximizing computational efficiency while minimizing costs and power consumption. Established in 2015 and headquartered in Emeryville, California, Ayar Labs also has an office in Santa Clara, California.

Robust.AI, founded by Anthony Jules in 2019 and based in San Carlos, California, develops advanced solutions that combine artificial intelligence, robotics, and human-centered design. The company has introduced its software suite, Grace, and a concept for a hardware product, Carter, aimed at enhancing interaction between humans and robots. These innovations target the warehousing industry, where a significant majority of operations remain unautomated, exacerbated by ongoing labor shortages in the global supply chain. Robust.AI's cognitive platform focuses on creating collaborative mobile robots that are context-aware, safe, and easy to implement, aiming to make robotics solutions more accessible across various sectors. By emphasizing common-sense AI and hybrid technology, the company seeks to address the challenges of robotics deployment and improve operational efficiency.

Agility Robotic's legged locomotion expertise is built on a history of academic research, including the bipedal walking and running robot ATRIAS. Agility Robotics is leveraging this work to create products that address the real world needs of rugged, efficient, and highly capable mobility platforms.

Lassogen, Inc. is a biotechnology company based in San Diego, California, established in 2019. It specializes in the development of lasso peptides, a novel therapeutic modality aimed at diagnosing and treating various diseases. Lassogen focuses on creating innovative therapeutics that target challenging receptors, utilizing a synthetic biology platform to develop lasso peptide-based drugs. These drugs are designed to address conditions such as cancer, autoimmunity, pain, inflammation, and disorders involving G protein-coupled receptors and ion channels. The company's work aims to harness recent technological advancements to explore the untapped potential of lasso peptides in medicine.

NextSilicon Ltd. is a technology company based in Tel Aviv-Yafo, Israel, founded in 2018. It specializes in designing and developing advanced computer processing technology that integrates software-defined hardware. The company offers innovative solutions aimed at enhancing high-performance computing (HPC) architectures, addressing fundamental challenges within the industry. By leveraging novel chip designs and software algorithms, NextSilicon enables businesses to accelerate compute-intensive applications, thereby creating opportunities for innovation in supercomputing. Through its unique approach, NextSilicon seeks to advance the future of computing technology.

Manifold Bio is a biotechnology company that features a platform that enables multiplexed quantitation of protein therapeutic designs, generating unprecedented data throughout the drug development process to unlock measurement-driven design. The company is building a protein barcoding platform to bring the power of multiplexed measurement to the development of protein therapeutics. It was founded in 2020 and headquartered in Boston, Massachusetts.

Bodyport Inc. is a company based in San Francisco, California, that specializes in the development of sensor-equipped weighing scales designed specifically for cardiac patients. The company's flagship offering is a biomarker-driven virtual clinic aimed at the prevention and management of heart disease. Utilizing proprietary sensor technology, Bodyport's device measures critical health metrics such as blood pressure, heart rate, heart rate variability, and arterial stiffness through the feet. This data helps healthcare providers assess patients' overall health and identify early signs of cardiovascular disease, facilitating timely interventions to prevent hospitalizations and enhance quality of life. In addition to its hardware, Bodyport offers an online patient portal and educational resources to support users in managing their health. The company was incorporated in 2015.

Fathom Radiant was created on the premise of applying first-principles thinking to create technology capable of enabling artificial general intelligence for the benefit of all. The company does not believe that the beneficial advancement of AI is unavoidable, and Faathom believes that as a company offering a critical layer in the AI technology stack, we can make a difference in how securely advanced AI systems are built and deployed.

Skydio, Inc. is a drone manufacturer based in Redwood City, California, founded in 2014. The company designs, assembles, and supports advanced drones that leverage artificial intelligence to enhance user experience. Skydio's drones are utilized in various sectors, including public safety, inspection, and defense, catering to consumers, enterprises, and government customers. Their products feature an array of cameras and proprietary computer vision technology that allows for real-time obstacle recognition and avoidance, enabling autonomous flight and intelligent decision-making. The company's initial offering was the R1 drone, which could autonomously track and film targets without human intervention. This was followed by the Skydio 2, which was more affordable and boasted improved tracking capabilities. The flagship model, the X2, is equipped with advanced features such as night vision and 100x zoom, allowing ordinary users to operate drones with ease. Skydio is supported by prominent investors and strategic partners, contributing to its growth in the competitive drone market.

Anjuna is a developer of a cloud security platform that provides hardware-grade protection for data, applications, and workloads in the public cloud. The company's technology enables enterprises to securely run their most sensitive workloads by leveraging advanced hardware-based secure computing technologies. Unlike traditional perimeter security solutions, which are often vulnerable to insider threats and malicious code, Anjuna's platform offers seamless end-to-end encryption through secure enclaves. This approach ensures that applications and data remain protected from unauthorized access, making the public cloud a safe computing resource for businesses.

Sentropy Technologies, Inc. is a technology company founded in 2018 and located in Palo Alto, California. The company specializes in developing advanced technologies aimed at protecting digital communities and brands from abuse, harassment, and malicious content. Its software solutions cater to a wide range of users, from small startup communities to large online forums, enabling businesses to create safer environments for their users and maintain their brand integrity.

Velo3D, Inc. specializes in additive manufacturing, specifically in the 3D printing of metal components. Founded in 2014 and based in Campbell, California, the company offers an integrated solution that includes the Sapphire Printer, a laser powder bed fusion system designed for support-free metal 3D printing, alongside the Flow print preparation software and the Assure quality assurance system. This innovative approach allows for greater design flexibility by minimizing the need for support structures, enhancing the manufacturing process for industries such as aerospace, energy, and industrial sectors. Velo3D's technology aims to improve performance, reduce costs, and expedite the production timeline of high-value metal parts, ensuring quality and reliability throughout the manufacturing process.

PsiQuantum is focused on developing the first utility-scale quantum computer to address significant global challenges. The company utilizes photonic qubits, which offer substantial advantages for creating a fault-tolerant, general-purpose quantum computer. By leveraging advanced semiconductor manufacturing capabilities, PsiQuantum aims to deliver quantum technology that can foster advancements across various sectors, including climate, healthcare, finance, energy, agriculture, transportation, and communications. This innovative approach positions PsiQuantum to contribute meaningfully to solving real-world problems through enhanced computational capabilities.

Virta Health Corp. is an online specialty medical clinic dedicated to reversing type 2 diabetes without the use of medications or surgery. Founded in 2014 and based in San Francisco, California, the company utilizes a combination of nutritional biochemistry, clinical expertise, data science, and digital solutions to deliver its innovative treatment. Through its continuous remote care platform, Virta provides extensive medical and behavioral support, which has shown significant results in clinical trials; 60% of enrolled patients achieved diabetes reversal after one year, while 94% of insulin users reduced or eliminated their insulin intake. The benefits of Virta's approach extend beyond diabetes, leading to improvements in blood pressure, inflammation, liver function, and body mass index (BMI), thereby transforming the lives of individuals affected by type 2 diabetes.

Relativity Space is an aerospace company based in Long Beach, California, that designs, develops, and manufactures 3D-printed rockets. Founded in 2015, the company aims to revolutionize rocket production through a vertically integrated technology platform that combines 3D printing, artificial intelligence, and autonomous robotics. This innovative approach allows for a significantly simplified supply chain, enabling the production of rockets with 100 times fewer parts in less than 60 days. In addition to manufacturing rockets, Relativity Space provides comprehensive services for satellite production, testing, and launching. The company is supported by prominent investors, highlighting its potential in the rapidly evolving aerospace sector.

FarmWise provides technology-based services that allow farmers to streamline farm operations and increase food production efficiency. It offers a productive mechanical weeding implement for vegetable crops, along with its exceptional training and support program. The company was founded in 2016 and is based in San Francisco, California.

Branch is a technology company specializing in deep linking solutions that enhance interactions between brands and users across digital platforms. Its innovative technology enables businesses to implement user-to-user referral programs, offering features such as rewarded referrals, content sharing, deep views, download banners, and personalized onboarding. Trusted by prominent brands like Instacart, Western Union, NBCUniversal, Zocdoc, and Sephora, Branch aims to help organizations acquire users, retain customers, and increase conversion rates. By providing tools for measuring and optimizing campaign performance, Branch supports growth-focused teams in maximizing the value of their digital strategies.

NextSilicon Ltd. is a technology company based in Tel Aviv-Yafo, Israel, founded in 2018. It specializes in designing and developing advanced computer processing technology that integrates software-defined hardware. The company offers innovative solutions aimed at enhancing high-performance computing (HPC) architectures, addressing fundamental challenges within the industry. By leveraging novel chip designs and software algorithms, NextSilicon enables businesses to accelerate compute-intensive applications, thereby creating opportunities for innovation in supercomputing. Through its unique approach, NextSilicon seeks to advance the future of computing technology.

Strand Therapeutics is a developer of a biotechnology platform intended to create gene therapies powered by synthetic biology.The company's offerings include immunotherapies to help cells produce target cancer-killing proteins during immunotherapy, enabling patients to improve their body's immune system to fight cancer.

Owl Labs Inc. specializes in developing and manufacturing innovative video conferencing technology, aimed at enhancing communication for hybrid and remote teams. Founded in 2014 and based in Somerville, Massachusetts, the company offers a range of products, including the Meeting Owl and Meeting Owl Pro. These smart conference cameras feature 360° views and advanced audio capabilities, allowing them to automatically focus on the speaker during meetings. Owl Labs' products are compatible with popular video conferencing platforms such as Google Hangouts, Skype, and GoToMeeting. The company's mission is to create inclusive and engaging video experiences that facilitate dynamic discussions in modern organizations.

RightHand Robotics, Inc. specializes in the manufacturing of robotic order-picking systems designed to enhance supply chain logistics and order fulfillment across various industries, including e-commerce, food handling, and flexible manufacturing. Founded in 2015, the company is headquartered in Cambridge, Massachusetts, with an additional office in Frankfurt, Germany. RightHand Robotics offers innovative solutions like the ReFlex SF, which features a 3D-printed palm equipped with advanced servos and compliant fingers, and the ReFlex TakkTile, a tactile sensor that aids in gentle object handling. Their technology enables robots to automatically grasp a wide range of items from bins and cases without the need for extensive data entry or parameter tuning, making their systems cost-effective and adaptable to changing business needs.

Ayar Labs, Inc. specializes in the development of optical interconnect technology, focusing on high-density electronic-photonic chiplets and lasers designed to enhance data transmission capabilities. Its flagship product, TeraPHY, is a monolithic in-package optical I/O solution that enables high bandwidth, low latency, and power-efficient short-reach interconnects, making it suitable for applications in artificial intelligence, high-performance computing, cloud computing, telecommunications, and aerospace. The company's innovative approach leverages industry-standard silicon processing techniques to create optical interconnect chiplets that replace traditional electrical-based I/O, addressing performance and efficiency challenges in the semiconductor and computing industries. By optimizing data movement within AI systems, Ayar Labs aims to alleviate compute and bandwidth bottlenecks associated with complex large language models, thereby maximizing computational efficiency while minimizing costs and power consumption. Established in 2015 and headquartered in Emeryville, California, Ayar Labs also has an office in Santa Clara, California.

RapidSOS, Inc. is an emergency response data platform that connects life-saving information from over 350 million connected devices directly to 911 and first responders. Founded in 2012 and headquartered in New York, the company serves public safety agencies globally, offering solutions such as the Clearinghouse, which enables users to send emergency requests and receive critical data from devices, and the Emergency API suite for direct data transmission to emergency services. Additionally, the RapidSOS Portal provides public safety agencies with secure access to essential data through a web-based tool. The platform supports more than 4,800 Emergency Communications Centers, protecting over 90% of the U.S. population during approximately 250 million emergencies each year, thereby enhancing the speed and effectiveness of emergency response.

Branch is a technology company specializing in deep linking solutions that enhance interactions between brands and users across digital platforms. Its innovative technology enables businesses to implement user-to-user referral programs, offering features such as rewarded referrals, content sharing, deep views, download banners, and personalized onboarding. Trusted by prominent brands like Instacart, Western Union, NBCUniversal, Zocdoc, and Sephora, Branch aims to help organizations acquire users, retain customers, and increase conversion rates. By providing tools for measuring and optimizing campaign performance, Branch supports growth-focused teams in maximizing the value of their digital strategies.

SUBPAC is a leading company in high-fidelity tactile audio technology, offering innovative solutions that enhance the audio experience across various fields, including music, gaming, virtual reality, cinema, and automotive applications. The company's unique technology transfers low sound frequencies directly to the user's body, providing a new physical dimension to sound. This capability allows creators and licensing partners to optimize their audio for deeper audience engagement. With a presence in major cities such as Los Angeles, San Francisco, Montreal, and London, SUBPAC is supported by a prominent team of investors and strategic partners, including notable figures from the music and sports industries. Their powerful hardware and software platform aims to revolutionize how sound is experienced, making it an essential tool for music producers and creators in various entertainment sectors.

Zippy.ai specializes in the development of autonomous robots aimed at enhancing last-mile delivery services for groceries and packages. The company employs advanced technologies such as artificial intelligence and GPS to create a fleet of robots that can efficiently deliver orders directly to consumers. These robots are designed to integrate smoothly into urban environments, facilitating everyday activities like food delivery and online shopping. By focusing on autonomous mobility, Zippy.ai aims to contribute to a future economy that relies on intelligent and independent robotic solutions, ultimately improving efficiency and productivity for its clients.

Virta Health Corp. is an online specialty medical clinic dedicated to reversing type 2 diabetes without the use of medications or surgery. Founded in 2014 and based in San Francisco, California, the company utilizes a combination of nutritional biochemistry, clinical expertise, data science, and digital solutions to deliver its innovative treatment. Through its continuous remote care platform, Virta provides extensive medical and behavioral support, which has shown significant results in clinical trials; 60% of enrolled patients achieved diabetes reversal after one year, while 94% of insulin users reduced or eliminated their insulin intake. The benefits of Virta's approach extend beyond diabetes, leading to improvements in blood pressure, inflammation, liver function, and body mass index (BMI), thereby transforming the lives of individuals affected by type 2 diabetes.

Relativity Space is an aerospace company based in Long Beach, California, that designs, develops, and manufactures 3D-printed rockets. Founded in 2015, the company aims to revolutionize rocket production through a vertically integrated technology platform that combines 3D printing, artificial intelligence, and autonomous robotics. This innovative approach allows for a significantly simplified supply chain, enabling the production of rockets with 100 times fewer parts in less than 60 days. In addition to manufacturing rockets, Relativity Space provides comprehensive services for satellite production, testing, and launching. The company is supported by prominent investors, highlighting its potential in the rapidly evolving aerospace sector.

Agility Robotic's legged locomotion expertise is built on a history of academic research, including the bipedal walking and running robot ATRIAS. Agility Robotics is leveraging this work to create products that address the real world needs of rugged, efficient, and highly capable mobility platforms.

MileZero is developing a Logistics Cloud that enables both traditional retailers and digital pioneers to compete in an era of rapid change and shifting consumer preferences, driven by the proliferation of mobile and on-demand services.

Fathom Radiant was created on the premise of applying first-principles thinking to create technology capable of enabling artificial general intelligence for the benefit of all. The company does not believe that the beneficial advancement of AI is unavoidable, and Faathom believes that as a company offering a critical layer in the AI technology stack, we can make a difference in how securely advanced AI systems are built and deployed.

Velo3D, Inc. specializes in additive manufacturing, specifically in the 3D printing of metal components. Founded in 2014 and based in Campbell, California, the company offers an integrated solution that includes the Sapphire Printer, a laser powder bed fusion system designed for support-free metal 3D printing, alongside the Flow print preparation software and the Assure quality assurance system. This innovative approach allows for greater design flexibility by minimizing the need for support structures, enhancing the manufacturing process for industries such as aerospace, energy, and industrial sectors. Velo3D's technology aims to improve performance, reduce costs, and expedite the production timeline of high-value metal parts, ensuring quality and reliability throughout the manufacturing process.

Skydio, Inc. is a drone manufacturer based in Redwood City, California, founded in 2014. The company designs, assembles, and supports advanced drones that leverage artificial intelligence to enhance user experience. Skydio's drones are utilized in various sectors, including public safety, inspection, and defense, catering to consumers, enterprises, and government customers. Their products feature an array of cameras and proprietary computer vision technology that allows for real-time obstacle recognition and avoidance, enabling autonomous flight and intelligent decision-making. The company's initial offering was the R1 drone, which could autonomously track and film targets without human intervention. This was followed by the Skydio 2, which was more affordable and boasted improved tracking capabilities. The flagship model, the X2, is equipped with advanced features such as night vision and 100x zoom, allowing ordinary users to operate drones with ease. Skydio is supported by prominent investors and strategic partners, contributing to its growth in the competitive drone market.

Anjuna is a developer of a cloud security platform that provides hardware-grade protection for data, applications, and workloads in the public cloud. The company's technology enables enterprises to securely run their most sensitive workloads by leveraging advanced hardware-based secure computing technologies. Unlike traditional perimeter security solutions, which are often vulnerable to insider threats and malicious code, Anjuna's platform offers seamless end-to-end encryption through secure enclaves. This approach ensures that applications and data remain protected from unauthorized access, making the public cloud a safe computing resource for businesses.

Canvas Technology, Inc. is a robotics company that specializes in mobile robotic technology tailored for factories and warehouses. Established in 2015 and located in Boulder, Colorado, the company designs and develops various robotic solutions, including carts, pallets, forklifts, and boxes, to facilitate the autonomous delivery of goods. Canvas Technology aims to create safe and efficient autonomous systems capable of operating in both indoor and outdoor environments. As of April 2019, it functions as a subsidiary of Amazon.com, Inc.

FarmWise provides technology-based services that allow farmers to streamline farm operations and increase food production efficiency. It offers a productive mechanical weeding implement for vegetable crops, along with its exceptional training and support program. The company was founded in 2016 and is based in San Francisco, California.

Blockfolio, Inc. is a company that specializes in creating a mobile application for cryptocurrency portfolio tracking and management. Founded in 2014 and based in Marina Del Rey, California, the application allows users to manage their cryptocurrency holdings by providing real-time prices, market data, and news updates. Users can add various cryptocurrencies to their portfolios, receive alerts on market movements, and connect their accounts with exchanges for automated tracking. Blockfolio aims to keep millions of users informed about developments in the cryptocurrency and blockchain industry, while maintaining a commitment to free access for both users and token team partners. As of August 2020, Blockfolio operates as a subsidiary of FTX Trading LTD.

uAvionix develops the world’s smallest, lightest and most affordable ADS-B transceivers and transponders, Ping. uAvionix’s Ping network system combines hardware, software, and real-time airspace mapping to enable companies to safely and reliably operate drones in the NAS. Based in Palo Alto, uAvionix has gathered a cross-disciplinary team of experts in embedded RF engineering, sUAS operations and compliance, hardware, software, and cloud services.

NVision Imaging Technologies GmbH, founded in 2015 and based in Ulm, Germany, specializes in the development and commercialization of innovative imaging and sensing applications grounded in quantum physics. The company has created a platform that polarizes natural metabolites, enabling their use as agents for imaging tumor metabolism through magnetic resonance imaging (MRI). This technology transforms standard magnetic resonance spectrometers into tools capable of assessing human metabolism, thereby enhancing the precision of cancer diagnostics and facilitating real-time monitoring of patient responses to therapy. By leveraging advances in quantum physics, NVision aims to make significant strides in the medical imaging and diagnostics sector.

Algolux is a Canadian AI software company that specializes in advanced perception solutions for various industries, including automotive, robotics, and video security. The company focuses on optimizing camera architectures to enhance image quality and supports both existing and new camera designs through cloud-based tools and embedded software. Founded on innovative research in deep learning, computer vision, and computational imaging, Algolux delivers robust solutions that address critical safety issues for applications such as advanced driver-assistance systems (ADAS), autonomous vehicles, fleets, and autonomous mobile robots. Their technology leverages machine learning and deep perception to improve performance in challenging conditions, including extreme lighting and adverse weather, ensuring clients achieve optimal results from their imaging systems.

Super Heroic, Inc. is a company that specializes in the design and manufacture of technology-enabled footwear and apparel for children. Founded in 2016 and based in Oakland, California, Super Heroic aims to empower children through play. Its flagship product, the TMBLR v1 shoe, features a unique design that eliminates laces and sock liners, incorporating a dual-density sole for enhanced flexibility and stability. In addition to footwear, the company has developed an application that helps families find activities, discover and rate playgrounds, participate in healthy challenges, and accurately measure children's feet for proper shoe sizing. Through its innovative products and services, Super Heroic encourages children to engage in active play while ensuring comfort and support.

Nauto, Inc. is an artificial intelligence technology company based in Palo Alto, California, specializing in software solutions for autonomous and commercial vehicles. Founded in 2015, Nauto develops an intelligent driver safety system that utilizes an after-market dual-camera device to collect and analyze visual data in real-time, aiming to reduce distracted driving and prevent collisions. This system includes features such as GPS, wireless connectivity, and night vision support, allowing fleet managers to monitor driver performance and vehicle safety effectively. Nauto also offers VERA (Vision Enhanced Risk Assessment), a scoring system that rates the frequency and severity of distracted driving incidents. The company collaborates with strategic partners including Allianz Insurance, Toyota, and BMW, and has expanded its presence with subsidiary locations in Dublin, Ireland, and Tokyo, Japan. Through its innovative technology, Nauto enhances safety and productivity for fleets while contributing to the advancement of self-driving technology.

Essential Products is a new type of company focused on creating consumer technology products for the 21st century. Founded by Andy Rubin, co-founder of Android, the world's most widely used operating system, Essential Products is headquartered in Palo Alto, California.

Lighthouse AI reinvents the home camera and makes intelligence readily available and helpful. These address common issues with today's internet-based cameras, such as false alerts caused by shadows and pets and scrubbing through video.