Perceptive Advisors

Impulse Dynamics N.V. is a medical device company that specializes in developing innovative electrical therapies for chronic heart failure. Founded in 1996 and headquartered in Willemstad, Curacao, the company also maintains offices in New York and Hong Kong, with product development centers located in New Jersey and Israel. Its primary offering, the CCM® therapy, utilizes cardiac contractility modulation technology to deliver non-excitatory electrical impulses to the heart, enhancing its contraction and improving blood flow to the body. This minimally invasive treatment option addresses the needs of heart failure patients who have limited alternatives. Impulse Dynamics conducts clinical trials to assess the safety and efficacy of its therapies and collaborates with universities and hospitals for ongoing research and development.

Impulse Dynamics N.V. is a medical device company that specializes in developing innovative electrical therapies for chronic heart failure. Founded in 1996 and headquartered in Willemstad, Curacao, the company also maintains offices in New York and Hong Kong, with product development centers located in New Jersey and Israel. Its primary offering, the CCM® therapy, utilizes cardiac contractility modulation technology to deliver non-excitatory electrical impulses to the heart, enhancing its contraction and improving blood flow to the body. This minimally invasive treatment option addresses the needs of heart failure patients who have limited alternatives. Impulse Dynamics conducts clinical trials to assess the safety and efficacy of its therapies and collaborates with universities and hospitals for ongoing research and development.

Agile Therapeutics, Inc. is a women's healthcare company based in Princeton, New Jersey, dedicated to the research, development, and commercialization of prescription contraceptive products. The company's lead product is Twirla, a once-weekly transdermal contraceptive patch that combines levonorgestrel and ethinyl estradiol, designed to provide a non-daily option for contraception. Agile Therapeutics is also advancing a pipeline of additional products and extensions related to Twirla, including regimens aimed at offering women extended cycles, shorter and lighter periods, and a progestin-only patch for those who cannot or prefer not to use estrogen. Utilizing proprietary Skinfusion technology, the company aims to deliver effective contraceptive solutions that address the unmet health needs of women today. Founded in 1997, Agile Therapeutics continues to focus on innovating women's healthcare options.

Founded in 2014, Clover Health is a healthcare company specializing in Medicare Advantage plans for seniors. It operates a Preferred Provider Organization platform that uses analytics and care management to improve member health and reduce avoidable spending.

Foamix Pharmaceuticals is a specialty pharmaceutical company based in Bridgewater, New Jersey, that focuses on the development and commercialization of proprietary topical drugs for dermatological conditions, as well as for ophthalmologic and gynecologic applications. Founded in 2014, the company utilizes its Molecule Stabilizing Technology platform to create innovative foam-based formulations. Its lead product, a first-in-class Topical Minocycline Foam, targets significant markets in dermatology and ophthalmology, having shown high efficacy and favorable safety in clinical trials for conditions such as acne and impetigo. Foamix's pipeline includes multiple drug candidates aimed at treating various skin conditions, including FMX101, FMX102, FMX103, and FDX104. The company is also engaged in development and licensing agreements with other pharmaceutical firms, enhancing its reach in the healthcare market.

ADMA Biologics, Inc. is a biopharmaceutical company focused on developing, manufacturing, and marketing specialty plasma-derived biologics aimed at treating immune deficiencies and infectious diseases in the United States. The company offers a range of products, including BIVIGAM and ASCENIV, both intravenous immune globulin therapies for primary humoral immunodeficiency, as well as Nabi-HB, which is used for acute exposure to Hepatitis B. ADMA is also involved in the development of additional plasma-derived therapeutics, particularly targeting infections like S. pneumonia. To support its operations, the company runs FDA-licensed source plasma collection facilities known as ADMA BioCenters, which contribute to the supply of plasma necessary for its product manufacturing. ADMA Biologics distributes its products through independent distributors, sales agents, specialty pharmacies, and other healthcare providers. Founded in 2004 and based in Ramsey, New Jersey, ADMA is dedicated to serving niche patient populations, particularly those with compromised immune systems.

Vyome Therapeutics develops innovative drugs targeting antibiotic-resistant acne and other pathogens, focusing on preventing resistance development. Its product pipeline includes VB 1953 for drug-resistant acne, along with anti-dandruff products like VB 001, VB 2421, VB 3222, and VB 7731. Vyome operates state-of-the-art facilities for research, development, formulation, analytics, biology, clinical trials, and regulatory processes.

Vyome Therapeutics develops innovative drugs targeting antibiotic-resistant acne and other pathogens, focusing on preventing resistance development. Its product pipeline includes VB 1953 for drug-resistant acne, along with anti-dandruff products like VB 001, VB 2421, VB 3222, and VB 7731. Vyome operates state-of-the-art facilities for research, development, formulation, analytics, biology, clinical trials, and regulatory processes.

Aquestive Therapeutics is a specialty pharmaceutical company dedicated to developing and commercializing innovative products to address unmet medical needs, with a focus on diseases of the Central Nervous System (CNS) and severe allergic reactions. Its portfolio includes marketed products like Suboxone, Emylif, Ondif, and Sympazan, along with pipeline candidates such as Libervant Buccal Film and AQST-108.

Arno Therapeutics, Inc. is a biopharmaceutical company based in Flemington, New Jersey, dedicated to developing innovative treatments for cancer and other life-threatening diseases. The company's product pipeline includes Onapristone, a type 1 anti-progestin hormone blocker currently undergoing Phase I/II clinical studies for various solid tumors, including breast and endometrial cancers in post-menopausal women and advanced castration-resistant prostate cancer in men. Additionally, Arno is advancing AR-12, an orally available cancer treatment that has completed Phase I studies for solid tumors and hematological malignancies, as well as AR-42, another oral therapy currently in Phase I investigator-initiated studies targeting hematological malignancies and solid tumors. The company has established collaboration agreements with several institutions, enhancing its research and development efforts.

Arno Therapeutics, Inc. is a biopharmaceutical company based in Flemington, New Jersey, dedicated to developing innovative treatments for cancer and other life-threatening diseases. The company's product pipeline includes Onapristone, a type 1 anti-progestin hormone blocker currently undergoing Phase I/II clinical studies for various solid tumors, including breast and endometrial cancers in post-menopausal women and advanced castration-resistant prostate cancer in men. Additionally, Arno is advancing AR-12, an orally available cancer treatment that has completed Phase I studies for solid tumors and hematological malignancies, as well as AR-42, another oral therapy currently in Phase I investigator-initiated studies targeting hematological malignancies and solid tumors. The company has established collaboration agreements with several institutions, enhancing its research and development efforts.

Outlook Therapeutics is a late-stage biopharmaceutical company dedicated to developing and commercializing monoclonal antibodies for various ophthalmic indications. Its lead product candidate, ONS-5010, is an ophthalmic formulation of bevacizumab currently in Phase-III trials for treating wet age-related macular degeneration and other retina diseases.

Outlook Therapeutics is a late-stage biopharmaceutical company dedicated to developing and commercializing monoclonal antibodies for various ophthalmic indications. Its lead product candidate, ONS-5010, is an ophthalmic formulation of bevacizumab currently in Phase-III trials for treating wet age-related macular degeneration and other retina diseases.

Champions Oncology, Inc. is a biotechnology company that specializes in developing and selling technology solutions aimed at personalizing oncology drug development and treatment. Headquartered in Hackensack, New Jersey, the company utilizes its Tumorgraft Technology Platform, which involves implanting human tumors in immune-deficient mice, to deliver Personalized Oncology Solutions (POS). These solutions aid physicians in crafting tailored treatment plans by providing tumor-specific data from drug panels. Additionally, Champions Oncology offers Translational Oncology Solutions (TOS) that support pharmaceutical and biotechnology companies in their drug development processes. The company's product offerings include TumorGraft implants and drug panels that evaluate how a patient's tumor responds to various oncology drugs or combinations. Founded in 1985 and previously known as Champions Biotechnology, Inc., Champions Oncology is committed to enhancing cancer treatment outcomes through innovative technologies.

Arno Therapeutics, Inc. is a biopharmaceutical company based in Flemington, New Jersey, dedicated to developing innovative treatments for cancer and other life-threatening diseases. The company's product pipeline includes Onapristone, a type 1 anti-progestin hormone blocker currently undergoing Phase I/II clinical studies for various solid tumors, including breast and endometrial cancers in post-menopausal women and advanced castration-resistant prostate cancer in men. Additionally, Arno is advancing AR-12, an orally available cancer treatment that has completed Phase I studies for solid tumors and hematological malignancies, as well as AR-42, another oral therapy currently in Phase I investigator-initiated studies targeting hematological malignancies and solid tumors. The company has established collaboration agreements with several institutions, enhancing its research and development efforts.