Originate Ventures

Micro Interventional Devices, Inc., founded in 2010 and based in Newtown, Pennsylvania, is a medical device company specializing in disruptive technologies for percutaneous and minimally invasive structural heart repair procedures. The company designs and manufactures devices such as Permaseal, which facilitates transapical access and closure for catheter-based procedures, and Minimally Invasive Annuloplasty technology for tricuspid and mitral repair. Additionally, they offer Endovalve, a percutaneous mitral valve replacement system, and Permavalve, a percutaneous mitral valve with active fixation. Their proprietary technology focuses on soft-tissue anchoring and delivery devices, enabling off-pump procedures and transforming open surgical techniques into transcatheter procedures.

ProtonMedia, Inc. is a provider of e-learning and virtual collaboration solutions, headquartered in Lansdale, Pennsylvania. Founded in 1998, the company specializes in developing ProtoSphere, a business collaboration software that creates a secure, three-dimensional environment tailored for various applications such as e-learning, virtual meetings, and collaborative events. This platform facilitates scientific research, development projects, and sales and manufacturing collaborations, all enhanced by rich data visualization. ProtonMedia serves a diverse range of clients across industries, including pharmaceuticals, medical devices, financial services, and technology, providing innovative tools to enhance organizational communication and learning experiences.

Holganix, Inc. is a manufacturer of plant-based bio-stimulant soil supplements designed to enhance soil health and promote sustainable growth in plants. Founded in 2010 and headquartered in Glen Mills, Pennsylvania, the company produces a range of products, including those for trees, shrubs, golf courses, and agriculture, as well as granular offerings. A key product, Holganix Bio 800+, contains beneficial microorganisms, microbe food, and nutrient enhancers that optimize soil conditions. By utilizing natural microorganisms, Holganix enables users to significantly reduce fertilizer usage—by as much as 90%—while achieving healthier and more vibrant lawns and trees. The company's products are distributed throughout the United States and are available for purchase online, reflecting its commitment to providing cost-effective and environmentally friendly solutions for landscape and lawn care professionals.

Micro Interventional Devices, Inc., founded in 2010 and based in Newtown, Pennsylvania, is a medical device company specializing in disruptive technologies for percutaneous and minimally invasive structural heart repair procedures. The company designs and manufactures devices such as Permaseal, which facilitates transapical access and closure for catheter-based procedures, and Minimally Invasive Annuloplasty technology for tricuspid and mitral repair. Additionally, they offer Endovalve, a percutaneous mitral valve replacement system, and Permavalve, a percutaneous mitral valve with active fixation. Their proprietary technology focuses on soft-tissue anchoring and delivery devices, enabling off-pump procedures and transforming open surgical techniques into transcatheter procedures.

ProtonMedia, Inc. is a provider of e-learning and virtual collaboration solutions, headquartered in Lansdale, Pennsylvania. Founded in 1998, the company specializes in developing ProtoSphere, a business collaboration software that creates a secure, three-dimensional environment tailored for various applications such as e-learning, virtual meetings, and collaborative events. This platform facilitates scientific research, development projects, and sales and manufacturing collaborations, all enhanced by rich data visualization. ProtonMedia serves a diverse range of clients across industries, including pharmaceuticals, medical devices, financial services, and technology, providing innovative tools to enhance organizational communication and learning experiences.

ProtonMedia, Inc. is a provider of e-learning and virtual collaboration solutions, headquartered in Lansdale, Pennsylvania. Founded in 1998, the company specializes in developing ProtoSphere, a business collaboration software that creates a secure, three-dimensional environment tailored for various applications such as e-learning, virtual meetings, and collaborative events. This platform facilitates scientific research, development projects, and sales and manufacturing collaborations, all enhanced by rich data visualization. ProtonMedia serves a diverse range of clients across industries, including pharmaceuticals, medical devices, financial services, and technology, providing innovative tools to enhance organizational communication and learning experiences.

Adhezion Biomedical is a privately-held medical device company based in Wyomissing, Pennsylvania. Founded in 2001, the company specializes in developing, manufacturing, and commercializing cyanoacrylate-based adhesive and infection prevention products. Their portfolio includes SurgiSeal for wound closure from surgical incisions and punctures, FloraSeal microbial sealant for use after skin preparations prior to surgery, and various animal health products. Adhezion Biomedical also offers solutions for surgical procedures, wound management, and infection prevention. The company was previously known as Spartan Medical Products before changing its name in 2008.