OrbiMed

OrbiMed Advisors LLC is a healthcare-focused investment firm founded in 1989, headquartered in New York City, with additional offices in various global locations. The firm manages approximately $5 billion in assets and specializes in private equity and venture capital investments across the healthcare sector, including pharmaceuticals, biotechnology, medical devices, and healthcare services. OrbiMed invests in companies at various stages, from early startups to established multinationals, and typically seeks to take majority stakes in its private equity investments. The firm employs fundamental analysis to guide its investment decisions and offers a range of financial services, including debt financing and structured capital, to both public and private healthcare companies. OrbiMed's investment strategy encompasses a broad spectrum of healthcare-related opportunities, targeting investments globally, primarily in North America, Europe, and Asia.
601 Lexington Avenue (at 53rd Street), 54th Floor New York, NY 10022-4629
1700 Owens Street Suite 540 San Francisco, CA 94158
Suite F 27, Grand Hyatt Plaza Santacruz (East) Mumbai, 400055, India
89 Medinat HaYehudim St Building E, 11th Floor Herzliya 4614001, Israel
Unit 4706, Raffles City Shanghai Office Tower 268 Xizang Middle Road Shanghai 200001, P.R. China
12/F International Commerce Centre 1 Austin Road West, Unit 01 Kowloon, Hong Kong

Roy Amariglio Ph.D

Principal

Mona Ashiya

Partner, Private Equity

Sven H. Borho

Partner

Evan Caplan

Principal

Clay DeMarcus

Vice President

Michael Eggenberg

Managing Director

Lars Enstrom

Managing Director

Robert Glassman

Venture Partner

Joshua Golomb

Partner, Public Equity

Carl L. Gordon

Managing Partner

Rishi Gupta

Partner

Geoffrey C. Hsu

Partner

Madeline Huber

Senior Associate

Alexandria Huynh

Analyst

Mark R. Jelley

Partner

Kip Kitur

Vice President

Jonathan Lee

Partner

Yifu Liu

Managing Director, Asia

Leo Ma

Senior Associate

Jonathan Mandelbaum

Vice President, Private Equity

John McGrath

Venture Partner

Anat Naschitz

Venture Partner

Carter Neild

Managing Partner

Anat Nursella

Venture Partner

Valerie Odegard

Venture Partner

Topher Orr

Partner

Jeff Peters

Venture Partner

Trevor Polischuk

Partner, Public Equity

Matthew S. Rizzo

General Partner

William F. Sawyer

Partner

Natasha Shervani

Vice President

Jonathan Silverstein

Co-Head of Private Equity and Managing Partner

Vivek Sivathanu

Vice President

Charles Steinman

Analyst

C. Scotland Stevens

Public Equity Partner

Jim Sullivan

Venture Partner

Clive Wang

Director, Asia

David Wang

Partner

Iris Wang

Partner

Steven Wang

Partner

Dimitrios Weedon

Managing Director

Matthew L. Wotiz

Principal

Stella Xing

Managing Director

Diyong Xu

Principal, Private Equity / Venture Capital

Nate Yee

Principal

Jessica Zhang

Senior Associate

Daniel Zhou

Managing Director

Mishael Zohar

Senior Associate

Guowei Wang Ph.D

Senior Managing Director, Asia and Partner

Carl Gordon Ph.D

Managing Partner and Head of Global Private Equity

Steven Wang Ph.D

Partner

Past deals in Medical

InspireMD

Post in 2023
InspireMD is a medical device company headquartered in Tel Aviv, Israel, specializing in the development and commercialization of its proprietary MicroNet stent platform technology for treating vascular and coronary diseases. The company offers products such as the CGuard carotid embolic prevention system, designed for carotid artery applications, and the MGuard Prime embolic protection system, intended for patients with acute coronary syndromes. InspireMD is also working on the NGuard neurovascular flow diverter, which aims to divert blood flow away from cerebral aneurysms. The company generates most of its revenue from the sales of the CGuard system, which integrates MicroNet technology with a self-expandable nitinol stent. Its products are distributed through local partners in various regions, including Europe, Latin America, the Middle East, and Asia.

Magenta Medical

Venture Round in 2023
Magenta Medical Ltd., founded in 2012 and based in Kadima, Israel, specializes in developing innovative device solutions for the treatment of acute and chronic heart failure. The company's primary focus is on a temporary venous catheter-based therapy designed specifically for patients experiencing acute decompensated heart failure. By addressing critical needs within this medical field, Magenta Medical aims to improve patient outcomes through its advanced therapeutic technologies.

Capstan Therapeutics

Series A in 2022
Capstan Therapeutics is advancing precision in vivo cell engineering to develop therapeutics for a broad range of disease categories with unmet or underserved clinical need.

Delfi Diagnostics

Series B in 2022
Delfi Diagnostics, Inc. is a biotechnology company based in Baltimore, Maryland, that focuses on the early detection of cancer through non-invasive blood tests. Founded in 2018, the company utilizes advanced technologies such as artificial intelligence and genome sequencing to identify unique patterns of DNA fragmentation in patients' blood. By leveraging machine learning, Delfi develops innovative testing systems aimed at recognizing cancer-associated cell-free DNA fragments, thereby enabling healthcare professionals to detect cancer at its most treatable stage. This approach facilitates timely and effective treatment options, ultimately aiming to improve patient outcomes and recovery speed.

LifeWell

Venture Round in 2022
LifeWell is a new entity formed through the merger of LifeCell’s diagnostics business and MFine.

MiroBio

Series B in 2022
MiroBio Ltd is a biotechnology company based in Oxford, United Kingdom, focused on developing antibody modulators for immune cell receptors aimed at treating autoimmune diseases. Founded in 2018, MiroBio leverages pioneering research from the University of Oxford to understand how immune cells communicate and are activated. This foundational knowledge allows the company to create innovative antibodies that stimulate specific immune cell signals, harnessing the body's natural control mechanisms to restore balance within the immune system. By activating these natural pathways, MiroBio's therapeutics aim to provide significant benefits to patients suffering from various autoimmune conditions, enabling clinicians to effectively manage overactive immune responses associated with these diseases.

Aerin Medical

Private Equity Round in 2022
Aerin Medical Inc. is a health technology company based in Sunnyvale, California, focused on developing non-invasive treatment solutions for nasal breathing disorders. Founded in 2011, the company specializes in therapeutic devices that utilize low-power radiofrequency energy to remodel nasal soft tissues, effectively addressing the underlying causes of conditions such as nasal obstruction and chronic rhinitis. Aerin Medical offers procedures and devices, including the VivAer procedure and the RhinAer procedure, along with their corresponding styluses, which allow ENT physicians to treat nasal airway conditions in an office setting under local anesthesia. These innovative solutions aim to improve patient outcomes by providing safe, quick, and effective relief from chronic nasal symptoms while minimizing downtime.

DarioHealth

Post in 2022
DarioHealth Corp. is a digital health company that specializes in developing and commercializing proprietary technology for laboratory testing via smartphones and mobile devices. Its flagship product, the Dario Smart Diabetes Management Solution, integrates a cloud-based software application with a compact blood glucose monitoring device. This solution enables users to manage their diabetes through real-time data tracking, coaching, and support, while also providing alerts and analysis of health trends. DarioHealth markets its products directly to consumers and through retail pharmacies, hospitals, and online channels. The company also offers a digital platform, DarioEngage, to enhance user engagement and support in managing chronic illnesses. Founded in 2011 and headquartered in Caesarea, Israel, DarioHealth emphasizes personalized, evidence-based interventions driven by data analytics and individual coaching, addressing various health concerns such as diabetes, hypertension, and weight management.

MDClone

Series C in 2022
MDClone Ltd. is a company that specializes in software designed to analyze medical records while ensuring patient privacy. Founded in 2016 and based in Beersheba, Israel, MDClone's platform generates synthetic medical records for fictitious patients. This innovative approach allows researchers to study disease behavior, medical practices, and various healthcare dynamics without exposing actual patient data. The platform creates fictitious individuals with unique characteristics, preserving essential relationships between them, thus maintaining the integrity of medical information while safeguarding privacy. By enabling health organizations to harness the value of their data assets, MDClone significantly enhances the ways medical information is gathered, analyzed, and utilized in research and service delivery.

HanBio Therapeutics

Series A in 2022
HanBio Therapeutics is a biotechnology company committed to researching and developing next generation transformative medicines.

ImmPACT Bio

Series B in 2022
ImmPACT Bio USA Inc. is a cell therapy company aiming to develop potent and selective engineered T-cells for the treatment of solid tumors. The Company's technology enables targeting loss-of-gene features of solid tumor cells, sparing normal, healthy tissues.

Beijing Tianxing

Series B in 2022
Beijing Tianxing is a clinical solutions company for sports medicine for implants, arthroscopy devices, and sports medicine equipment.

Odyssey Therapeutics

Series A in 2021
Odyssey Therapeutics is a biotechnology company pioneering the efficient development of next-generation immunomodulators and oncology medicines. Odyssey is making a transformational impact on the field of drug discovery and is accelerating the path to clinical development to drive the creation of more effective precision medicines.

Alpheus Medical

Series A in 2021
Alpheus Medical provides a novel sonodynamic therapy platform targeting solid body cancers. Alpheus Medical also provides a non-invasive drug-device combination for outpatient treatment of recurrent glioblastoma multiforme (rGBM).

Edge Medical Robotics

Series C in 2021
Edge Medical Robotics, Inc. is a company that specializes in designing and developing advanced surgical equipment. Founded on May 4, 2017, and based in Longgang, Shenzhen, China, the company is dedicated to researching and promoting cutting-edge medical technology. Its mission focuses on enhancing surgical safety and treatment efficacy, aiming to elevate the overall standards of healthcare. Through a commitment to excellence and precision in product development, Edge Medical Robotics strives to contribute positively to the improvement of social health outcomes.

PierianDx

Venture Round in 2021
PierianDx, Inc. is a technology company that develops a genomic software-as-a-service (SaaS) solution designed to manage, analyze, and interpret complex genomic tests for clinical laboratories in the United States. The company offers the Clinical Genomicist Workstation, a platform that streamlines the workflow for patient cases, handling everything from sequencing and analysis to report generation and integration with electronic health records. PierianDx aims to enhance the adoption of genomic sequencing in healthcare, enabling physicians to diagnose and treat patients with cancer and other complex diseases more effectively. The company also provides consulting and technical services to support its clients, which include health systems, children's hospitals, comprehensive cancer centers, and reference laboratories. Founded in 2014 and headquartered in Saint Louis, Missouri, PierianDx has established itself as a trusted source for advanced genomic reporting and decision support in clinical care.

Scout Bio

Series B in 2021
Scout Bio, Inc. researches and develops one-time therapies for major chronic pet health conditions using veterinary biotechnology and gene therapy. It offers therapies for anemia associated with chronic kidney disease (CKD) in cats. The company offers pet therapeutics, including small molecular drugs, protein therapies, and gene therapies. Scout Bio, Inc. was founded in 2016 and is headquartered in Philadelphia, Pennsylvania.

PharmEasy

Venture Round in 2021
PharmEasy is a leading pharmacy aggregator in India that operates an online drug delivery platform aimed at enhancing the supply chain of pharmaceuticals. By digitizing the process, it connects patients with local pharmacy stores and diagnostic centers, ensuring they can easily access a wide range of medicines and healthcare products. The platform is designed to make healthcare services more accessible and affordable, emphasizing the importance of good health for everyone. Through its services, PharmEasy strives to simplify the healthcare experience for patients, allowing them to fulfill their medical needs efficiently.

LifeCell International

Venture Round in 2021
LifeCell International, established in 2004 and headquartered in Chennai, is a private stem cell bank that revolutionized umbilical cord stem cell banking in India. The company has evolved into a comprehensive provider of stem cell solutions, offering a wide range of services that include multi-service stem cell banking, research and development, clinical trials, and therapies. LifeCell also provides menstrual stem cell banking and point-of-care therapies targeting orthopedic and vascular conditions. With over 100 service centers across India and the Gulf Cooperation Council countries, LifeCell aims to enhance health prospects for future generations by enabling parents to safeguard their newborns' health and mitigate potential disease burdens.

ADARx Pharmaceuticals

Series B in 2021
ADARx Pharmaceuticals, Inc. is a clinical-stage biotechnology company based in San Diego, California, focused on the research and development of RNA editing therapeutics. Founded in 2019, the company specializes in utilizing a proprietary platform that leverages endogenous enzymes, specifically adenosine deaminase acting on RNA (ADAR), to precisely target and correct single point mutations in mRNA transcripts. This innovative approach aims to restore the production of functional proteins, addressing various genetic mutations that contribute to diseases. ADARx is developing a pipeline of therapeutics designed to treat a range of conditions, including genetic, cardiometabolic, complement-mediated, and central nervous system diseases, offering potential solutions for previously incurable ailments.

Disc Medicine

Series B in 2021
Disc Medicine, Inc. is a biotechnology company focused on developing therapeutics based on human genetics to address ineffective red blood cell production in hematologic diseases. The company specializes in programs targeting the hepcidin metabolism axis for the treatment of disorders related to hepcidin. Founded in 2017 and headquartered in Cambridge, Massachusetts, Disc Medicine is led by a team of experienced scientists and industry experts, supported by a panel of advisors with a proven history in discovering and developing innovative therapies. The company was established with backing from Atlas Venture, along with contributions from Novo Ventures and Access Biotechnology.

Humacyte

Post in 2021
Humacyte, Inc. is a medical research and development company based in Morrisville, North Carolina, focused on creating and commercializing human tissue-based products for regenerative medicine and vascular surgery. Founded in 2004, the company specializes in developing acellular extracellular matrices derived from banked vascular smooth muscle cells, which are decellularized to prevent rejection. These matrices serve as tissue-engineered grafts, providing solutions for patients requiring vascular repair or replacement. Humacyte's innovative biotechnology platform aims to deliver universally implantable bioengineered human tissues and organs, addressing a variety of diseases, injuries, and chronic conditions, ultimately seeking to enhance patient outcomes and transform medical practices.

Miaoshou Doctor

Series F in 2021
Miaoshou Doctor is a healthcare service platform founded in 2015 by Tao He and Daoliang Han, based in Beijing. The platform facilitates communication between healthcare professionals and patients, focusing on the management of post-diagnosis outcomes. It enables doctors to actively follow up with patients through additional counseling and prescriptions, enhancing the overall patient care experience. By providing tools for effective interaction, Miaoshou Doctor aims to improve health management for both patients and doctors.

RIMAG

Series D in 2021
Rimag provides medical imaging service. The company engages in medical imaging center operation, relevant cloud technology development, and talent training. The company was founded in 2014 and is based in Shenzhen, China.

Pulnovo Medical

Venture Round in 2021
Pulnovo Medical specializes in the development and production of innovative medical devices aimed at treating pulmonary hypertension. The company focuses on radiofrequency ablation technology, offering advanced solutions such as pulse radiofrequency ablation catheters and instruments. These pioneering products are designed to enhance the resilience and quality of life for patients suffering from pulmonary hypertension and heart failure. Pulnovo Medical holds global invention patents for its high-frequency ablation equipment and intravascular catheters, reflecting its commitment to advancing treatment methodologies in this critical area of healthcare.

Adela

Series A in 2021
Adela is focused on the detection of cancer and other high-morbidity, high-mortality conditions through a routine blood test.

InSilico Medicine

Series C in 2021
InSilico Medicine, Inc. is an artificial intelligence company focused on drug discovery, biomarker development, and aging research. Founded in 2014 and headquartered in Baltimore, Maryland, the company employs advanced AI technologies, including deep learning and generative adversarial networks, to create novel molecular structures for diseases with known and unknown targets. Its comprehensive platform covers all stages of drug development, from discovery to clinical trials. Key initiatives include Pharma.AI, which offers machine learning services to various industries, and Young.AI, which predicts biological age. InSilico Medicine also engages in internal drug discovery programs targeting conditions such as cancer, Parkinson's Disease, and age-related disorders. Additionally, the company has partnered with Life Extension to develop nutraceutical products using its bioinformatics and deep learning techniques. Through its innovative solutions, InSilico Medicine aims to enhance personalized healthcare and mitigate the effects of aging.

Binx

Series E in 2021
Binx Health Limited is an in vitro diagnostics company based in Trowbridge, United Kingdom, specializing in the development of diagnostic instruments and disposable cartridge systems for decentralized laboratory and point-of-care environments. The company's flagship products include the io System, which detects infectious diseases such as chlamydia and MRSA, and Callisto, designed to accommodate various testing throughput requirements. Binx Health focuses on providing solutions for sexually transmitted infections and hospital-acquired infections. The company aims to enhance healthcare accessibility by delivering on-demand testing directly to consumers, utilizing its proprietary, desktop, PCR-based platforms and mobile offerings. Established in 2005, Binx Health has formed a strategic partnership with Sherlock Biosciences to further advance its innovative healthcare solutions.
Magenta is focused on improving the patient experience in transplant medicine, with the goal of bringing this lifesaving procedure to more patients. Over the past 50 years, stem cell transplantation has been used in more than 1M patients worldwide. It is currently the only treatment with the potential to cure some of the most devastating hematologic cancers and autoimmune diseases. Despite the increased use and clinical advancements over the past several decades, stem cell transplant remains a high-risk last-resort therapeutic option due to the toxicity and potential long-term side effects.

Edda Technology

Private Equity Round in 2021
Developer of a computer-assisted radiology technology designed to enhance efficiency and effectiveness in imaging-guided cancer treatment. The company's technology offers a platform that supports a patient-specific, disease-targeted and multi-disciplinary approach to cancer treatment, enabling physicians to use advanced clinical applications, including automated volumetric organ segmentation and virtual planning and treatment simulation.

Crossover

Series D in 2021
Crossover Health, Inc. is a healthcare provider focused on delivering comprehensive workplace healthcare services tailored for employers and their employees. Founded in 2010 and headquartered in Aliso Viejo, California, the company operates health centers in various locations, including Silicon Valley. Crossover Health offers a wide range of services, such as primary care, urgent care, preventive care, chronic disease management, health education, physical therapy, and remote care, among others. By integrating various health and wellness benefits with technology-enabled services, Crossover Health aims to enhance access to care and reduce healthcare costs for companies. The firm collaborates closely with client partners to customize health services based on health analytics, fostering a culture of health ownership among employees while improving both the quality of care and the overall employee experience.

NewMed Medical

Series C in 2021
NewMed Medical Co., Ltd. is a Shanghai-based company focused on the research, development, manufacture, and marketing of interventional artificial heart valve systems. Established in 2015, the company specializes in producing artificial heart valves and transcather implantation systems designed to replace diseased mitral valves. These innovative products aim to simplify heart valve replacement surgery, thereby reducing treatment risks and facilitating quicker patient recovery while also lowering surgical costs. Through its advancements in medical technology, NewMed Medical contributes to improved outcomes in cardiac care.

Chemomab

Post in 2021
ChemomAb Ltd. is a clinical-stage biopharmaceutical company based in Tel Aviv, Israel, founded in 2011. The company focuses on developing proprietary monoclonal antibodies aimed at treating autoimmune, inflammatory, and fibrotic diseases, including rare conditions. Its leading therapeutic candidate, CM-101, has undergone extensive pre-clinical testing in animal models that simulate human disorders, demonstrating promising safety and efficacy along with a novel mechanism of action. Through its innovative approach, ChemomAb aims to address unmet medical needs in immune-mediated and fibrotic disorders.

AnchorDx

Series C in 2021
AnchorDx is a company focused on advancing precision medicine through its development of next-generation sequencing techniques, particularly utilizing molecular liquid biopsies. This approach offers non-invasive access to genetic information, enabling patients to gain insights into their physiological conditions and prepare for potential future health issues. With a core team boasting over 20 years of experience in cancer genomics, genetics, and bioinformatics, AnchorDx aims to establish itself as a leading global provider of precision medical solutions. The company collaborates with various middle and downstream enterprises, fostering a comprehensive industrial chain that spans from academic research to clinical product transformation. Additionally, AnchorDx has formed partnerships with numerous large-scale third-party inspection agencies, hospitals, and research institutes, contributing to the development of independent intellectual property rights and competitive clinical testing products that deliver accurate and comprehensive services to patients, doctors, and medical institutions.

Miaoshou Doctor

Series E in 2021
Miaoshou Doctor is a healthcare service platform founded in 2015 by Tao He and Daoliang Han, based in Beijing. The platform facilitates communication between healthcare professionals and patients, focusing on the management of post-diagnosis outcomes. It enables doctors to actively follow up with patients through additional counseling and prescriptions, enhancing the overall patient care experience. By providing tools for effective interaction, Miaoshou Doctor aims to improve health management for both patients and doctors.

Gemini Therapeutics

Post in 2021
Gemini Therapeutics, Inc. is a precision medicine company established in 2015 and based in Cambridge, Massachusetts. The company specializes in developing therapies for patients with dry age-related macular degeneration (AMD) and related rare genetic diseases. Gemini's approach focuses on addressing genetically-defined conditions by creating therapeutic candidates that target specific molecular abnormalities prevalent in patients with significant clinical needs. Their diverse pipeline features a range of innovative treatment modalities, including monoclonal antibodies, recombinant proteins, and gene therapies. The company has secured funding from prominent life science investors and collaborates with academic institutions globally to advance its mission of delivering potentially first-in-class therapeutics.

Delfi Diagnostics

Series A in 2021
Delfi Diagnostics, Inc. is a biotechnology company based in Baltimore, Maryland, that focuses on the early detection of cancer through non-invasive blood tests. Founded in 2018, the company utilizes advanced technologies such as artificial intelligence and genome sequencing to identify unique patterns of DNA fragmentation in patients' blood. By leveraging machine learning, Delfi develops innovative testing systems aimed at recognizing cancer-associated cell-free DNA fragments, thereby enabling healthcare professionals to detect cancer at its most treatable stage. This approach facilitates timely and effective treatment options, ultimately aiming to improve patient outcomes and recovery speed.

Noctrix Health

Series B in 2021
Noctrix Health, Inc. is an early-stage medical device company based in Menlo Park, California, founded in 2018. The company specializes in the development of therapeutic wearable devices aimed at treating chronic neurological and sleep disorders. By focusing on innovative therapies, Noctrix Health seeks to address the unmet needs of patients suffering from these conditions.

Zylox

Series C in 2020
Zylox Medical Device Co. was founded in the beautiful city of Hangzhou in 2012 by a group of highly skillful and experienced returnees from the US and Europe. They have on average 5-20 years of working experiences in various functional areas such as research and development, management, and manufacturing in leading device makers including Johnson & Johnson, Medtronic, and Abbott before returning to China. Since its inception, Zylox has developed an increasingly rich product pipeline of interventional and implantable peripheral vascular devices such as PTA balloons, PTA drug-coated Balloons (PTA DCB), superficial femoral artery (SFA) stent, drug-eluting SFA stent, and other vascular accessories. Zylox strives to continuously innovate and provide patients with superior quality medical devices.

Q32 Bio

Series B in 2020
Q32 Bio is a biotechnology company developing treatments for patients with severe autoimmune and inflammatory diseases. Q32 Bio is addressing dysregulation to help patients take back control of their lives in diseases with few to no treatment options, or those diseases where current therapeutics provide inadequate relief. Q32 Bio consists of a team of scientists and industry veterans with strong expertise in immunology. The team has a strong track record of discovering and developing new and innovative therapies.

Q32 Bio

Series B in 2020
Q32 Bio is a biotechnology company developing treatments for patients with severe autoimmune and inflammatory diseases. Q32 Bio is addressing dysregulation to help patients take back control of their lives in diseases with few to no treatment options, or those diseases where current therapeutics provide inadequate relief. Q32 Bio consists of a team of scientists and industry veterans with strong expertise in immunology. The team has a strong track record of discovering and developing new and innovative therapies.

Azura Ophthalmics

Series C in 2020
Azura Ophthalmics is a clinical-stage company focused on developing innovative treatments for Meibomian Gland Dysfunction (MGD), a leading cause of dry eye disease (DED). By addressing the underlying causes of MGD, Azura aims to improve the health and quality of life for millions affected by this and other ocular surface diseases, where effective treatment options are often limited. The company is advancing a unique portfolio of compounds in conjunction with a novel drug delivery platform, enabling healthcare professionals to better manage these conditions. Based in Tel Aviv-Yafo, Israel, Azura also has operational presence in Australia and the United States, supported by a management team with a strong track record in the development and commercialization of novel ocular therapies.

Olema Oncology

Series C in 2020
Olema Oncology is a clinical-stage biopharmaceutical company dedicated to developing targeted therapies for women's cancers, particularly estrogen receptor (ER)-positive breast cancer. The company's lead candidate, OP-1250, is an ER antagonist and selective ER degrader currently undergoing Phase 1/2 clinical trials for the treatment of metastatic or locally advanced, ER-positive, and human epidermal growth factor receptor 2-negative breast cancer. Olema's research focuses on utilizing its expertise in endocrine-driven cancers and the molecular mechanisms of the ER to create more effective treatments that aim to improve patient outcomes. In addition to OP-1250, Olema is advancing another drug candidate, OP-3136, further enriching its pipeline. Established in 2006 and headquartered in San Francisco, California, Olema is committed to transforming the standard of care for women facing these challenging diagnoses.

Ruipeng Pet Hospital

Venture Round in 2020
Ruipeng Pet Hospital, located in Shenzhen, specializes in a comprehensive range of pet care services. The hospital provides medical and beauty care for pets, including healthcare, foster care, bathing, SPA treatments, grooming, food, and entertainment. By offering both digital and clinical services, Ruipeng aims to ensure that pet owners can access high-quality care for their animals efficiently. The organization also includes online shopping options to further support pet owners in meeting their pets' needs.

CoreMap

Series A in 2020
CoreMap, Inc. develops a diagnostic technology for electrophysiologists for treating atrial fibrillation. It offers CoreMap micro-electrode solution for mapping tissue properties (ability to map sequentially). The company also provides CoreMap ultra-high resolution electrodes reveal the details of activation despite fibrillation. The company was incorporated in 2016 and is based in Winooski, Vermont.

I-Mab HK

Post in 2020
I-Mab HK is a clinical-stage biopharmaceutical company focused on the discovery, development, and commercialization of innovative biologics aimed at addressing significant unmet medical needs, particularly in the areas of cancer and autoimmune disorders. The company is engaged in developing a diverse pipeline of product candidates, including Felzartamab, a CD38 antibody in Phase III trials for multiple myeloma, and Eftansomatropin, a long-acting human growth hormone for pediatric growth hormone deficiency. Other notable candidates include Olamkicept, an IL-6 blocker for ulcerative colitis, and Enoblituzumab, a B7-H3 antibody for head and neck cancer. I-Mab HK also has preclinical compounds targeting various conditions, including cancers and autoimmune diseases. The company has established strategic collaborations, such as with AbbVie, to enhance its development efforts. Founded in 2014 and headquartered in Shanghai, I-Mab HK is dedicated to advancing therapies that improve patient outcomes across various therapeutic areas.

ImmPACT Bio

Series A in 2020
ImmPACT Bio USA Inc. is a cell therapy company aiming to develop potent and selective engineered T-cells for the treatment of solid tumors. The Company's technology enables targeting loss-of-gene features of solid tumor cells, sparing normal, healthy tissues.

Aerin Medical

Venture Round in 2020
Aerin Medical Inc. is a health technology company based in Sunnyvale, California, focused on developing non-invasive treatment solutions for nasal breathing disorders. Founded in 2011, the company specializes in therapeutic devices that utilize low-power radiofrequency energy to remodel nasal soft tissues, effectively addressing the underlying causes of conditions such as nasal obstruction and chronic rhinitis. Aerin Medical offers procedures and devices, including the VivAer procedure and the RhinAer procedure, along with their corresponding styluses, which allow ENT physicians to treat nasal airway conditions in an office setting under local anesthesia. These innovative solutions aim to improve patient outcomes by providing safe, quick, and effective relief from chronic nasal symptoms while minimizing downtime.

MobileODT

Series C in 2020
MobileODT Ltd specializes in developing optical diagnostic devices and software focused on early cancer detection, particularly cervical cancer. The company's flagship product, the EVA COLPO, is a portable, internet-connected colposcope that is FDA-cleared and designed for ease of use. MobileODT also offers EVA SANE, a secure platform for managing patient information, and EVA WELL, a digital visualization tool for gynecologic exams. Their offerings include a mobile application for remote image capture and patient tracking, along with a cloud-based portal for collaboration and reporting. In addition, the company provides tools for documenting violence and abuse and plans to expand its product line to cover other medical areas such as ENT and dermatology. Established in 2012 and headquartered in Tel Aviv, Israel, with an office in New York, MobileODT has gained recognition in various markets, particularly the United States, where it is becoming a standard for visual diagnostics in healthcare settings.

PMV Pharmaceuticals

Series D in 2020
PMV Pharma is developing first-in-class p53 and p53 pathway modulators for the treatment of cancer. Bringing together leaders in the field to utilize over three decades of p53 biology, PMV Pharma combines unique biological understanding with pharmaceutical development focus.

Perfuse Therapeutics

Venture Round in 2020
Perfuse Therapeutics is a biotechnology company dedicated to developing innovative therapies for eye diseases, with a primary focus on glaucoma. The company aims to improve retinal perfusion, which is critical in addressing various retinal conditions. By utilizing a novel mechanism to enhance blood flow to the retina, Perfuse Therapeutics seeks to provide treatment options that can slow the progression of glaucoma, as well as other retinal diseases such as non-proliferative diabetic retinopathy and retinal vein occlusion. Through its research and development efforts, the company is working to advance the standard of care for patients suffering from these conditions.

MBX Biosciences

Series A in 2020
MBX Biosciences, Inc. is a biotechnology company based in Carmel, Indiana, specializing in the development of therapeutics for rare endocrine disorders. Founded in 2018, the company aims to address unmet medical needs by discovering and commercializing innovative treatments for endocrine diseases that affect hormonal regulation in the body. MBX Biosciences focuses on creating first-in-class therapies, particularly utilizing peptides to target rare genetic conditions related to glandular hormone secretion.

New Horizon Health

Series E in 2020
New Horizon Health, founded in 2015 and headquartered in Hangzhou, China, specializes in developing advanced technologies for the detection and screening of gastrointestinal cancers, particularly gastric and colorectal cancers. The company offers innovative products based on fecal gene analysis (FIT-DNA) technology, enabling users to conduct at-home tests that identify signs of colon cancer and significant adenomas. This technology facilitates earlier detection of precancerous lesions compared to conventional blood tests. By leveraging big data and artificial intelligence, New Horizon Health enhances its cancer screening solutions, aiming to improve public health outcomes. The company also emphasizes its commitment to making early cancer screening accessible to households, thereby striving to reduce the incidence and mortality associated with cancer.

Harbour BioMed

Series C in 2020
Harbour BioMed is a biotechnology company focused on discovering and developing therapeutics for cancer and inflammatory diseases, particularly through immuno-oncology. Established in 2016 and headquartered in Shanghai, China, the company employs two patented transgenic mouse platforms for generating fully human monoclonal antibodies and heavy chain only antibodies, enabling the creation of bispecific antibodies and other therapeutic compounds. Harbour BioMed's development pipeline includes products targeting various conditions, such as autoimmune diseases and respiratory infections. The company also licenses its antibody platforms to other firms and academic institutions via its Harbour Antibodies subsidiary. It has formed strategic collaborations with several notable organizations, including The Wistar Institute and WuXi Biologics, and maintains partnerships with various biopharmaceutical companies. With operations in Cambridge, Massachusetts, and antibody platform innovation in Rotterdam, the Netherlands, Harbour BioMed is positioned to enhance drug discovery and development across multiple global markets.

MabPlex

Series B in 2020
MabPlex International Ltd provides contract development and manufacturing of biopharmaceuticals including, monoclonal antibodies (mAbs), recombinant proteins, Antibody Drug Conjugates (ADCs) and bispecifics. It offers customized mammalian cell medium, cell banking, monoclonal antibodiy active pharmaceutical ingredient (API) manufacturing, and biologics and ADC fill and finish manufacturing. The company was founded in 2013 and is based in Yantai, China with an additional office in Fremont, California.

Mereo Biopharma

Post in 2020
Mereo is based in London and was founded in March 2015 to fund and develop novel, innovative specialist focused products from large pharmaceutical or biotechnology companies. Pharmaceutical companies face increasingly difficult choices in the allocation of internal resources to their drug development programs. With significant P&L constraints and rich pipelines it has become increasingly difficult for many companies to fully fund and advance development all of their drug candidates, especially beyond Phase 2. Mereo has been formed to take advantage of the global pharmaceutical industry's drive for creative ways to progress their clinical development pipelines. Mereo has acquired an initial mid-late stage portfolio of three exceptionally well characterised novel products for the treatment of diseases with considerable unmet medical need from Novartis Pharmaceuticals. Each of these programmes has a comprehensive dataset for both pre-clinical and proof-of-concept clinical studies. Additional product opportunities are under evaluation. Mereo's focus is the development of innovative medicines that have the potential to significantly transform the lives of patients suffering from rare and other specialised conditions around the world. To do this, the Company depends on the combination of its team's expertise in selecting and acquiring product opportunities, creating value in the development pipeline and structuring creative transactions. Mereo's internal expertise is complemented by a unique partnership with a leading global CRO, ICON. Mereo combines the operational discipline and efficiency of a small company with the financial resources to conduct comprehensive clinical studies. Mereo will rapidly progress each of the products through further value inflection points before partnering or divesting its products. The Company also has the option to directly commercialise products, for example in orphan disease indications.

Q32 Bio

Series A in 2020
Q32 Bio is a biotechnology company developing treatments for patients with severe autoimmune and inflammatory diseases. Q32 Bio is addressing dysregulation to help patients take back control of their lives in diseases with few to no treatment options, or those diseases where current therapeutics provide inadequate relief. Q32 Bio consists of a team of scientists and industry veterans with strong expertise in immunology. The team has a strong track record of discovering and developing new and innovative therapies.

TytoCare

Venture Round in 2020
TytoCare Ltd. is a healthcare technology company that develops handheld devices and applications for on-demand medical examinations and remote diagnoses. Founded in 2012 and based in Netanya, Israel, with an office in New York, the company offers three main telehealth products: TytoHome for consumers, TytoPro for professionals, and TytoClinic for remote care settings. These tools enable users to conduct self-examinations of various health conditions, such as ear infections, respiratory issues, and abdominal pain, by assessing the heart, lungs, skin, throat, ears, and body temperature. The platform facilitates virtual consultations by connecting patients with healthcare professionals, allowing for diagnosis and prescriptions as needed. TytoCare's technology incorporates a cloud-based data repository, analytics, and machine learning algorithms to enhance user experience and diagnostic accuracy. The company has established a strategic partnership with Novant Health to further its mission of making healthcare accessible and convenient.

Keros Therapeutics

Series C in 2020
Keros Therapeutics, Inc. is a clinical-stage biopharmaceutical company dedicated to developing novel treatments for patients with hematological and musculoskeletal disorders that have significant unmet medical needs. The company's lead product candidate, KER-050, targets low blood cell counts, including anemia and thrombocytopenia, in patients with myelodysplastic syndromes and myelofibrosis. Additionally, Keros is advancing KER-047, a small molecule therapeutic in Phase 1 clinical trials, aimed at treating anemia related to elevated hepcidin levels and fibrodysplasia ossificans progressiva. The company's third candidate, KER-012, focuses on disorders associated with bone loss, such as osteoporosis and osteogenesis imperfecta, as well as pulmonary arterial hypertension. Founded in 2015 and based in Lexington, Massachusetts, Keros Therapeutics is recognized for its expertise in the role of the Transforming Growth Factor-Beta family of proteins, which regulate red blood cell and platelet production, along with muscle and bone maintenance.

NewMed Medical

Series B in 2020
NewMed Medical Co., Ltd. is a Shanghai-based company focused on the research, development, manufacture, and marketing of interventional artificial heart valve systems. Established in 2015, the company specializes in producing artificial heart valves and transcather implantation systems designed to replace diseased mitral valves. These innovative products aim to simplify heart valve replacement surgery, thereby reducing treatment risks and facilitating quicker patient recovery while also lowering surgical costs. Through its advancements in medical technology, NewMed Medical contributes to improved outcomes in cardiac care.

Sonendo

Private Equity Round in 2020
Sonendo, Inc. is a medical technology company that focuses on advancing dental care through innovative devices for root canal therapy. Based in Laguna Hills, California, Sonendo has developed the GentleWave® System, which enhances the cleaning and disinfection of tooth canals, improving clinical outcomes and efficiency compared to traditional methods. The company operates primarily through two segments: the Product segment, which includes sales of the GentleWave System and its related instruments, and the Software segment, which encompasses TDO® Software—widely recognized as a leading practice management solution for endodontics. Since its incorporation in 2006, Sonendo has aimed to transform dentistry by promoting effective treatments that preserve tooth structure and enhance patient care.

Chemomab

Series C in 2019
ChemomAb Ltd. is a clinical-stage biopharmaceutical company based in Tel Aviv, Israel, founded in 2011. The company focuses on developing proprietary monoclonal antibodies aimed at treating autoimmune, inflammatory, and fibrotic diseases, including rare conditions. Its leading therapeutic candidate, CM-101, has undergone extensive pre-clinical testing in animal models that simulate human disorders, demonstrating promising safety and efficacy along with a novel mechanism of action. Through its innovative approach, ChemomAb aims to address unmet medical needs in immune-mediated and fibrotic disorders.

PMV Pharmaceuticals

Series C in 2019
PMV Pharma is developing first-in-class p53 and p53 pathway modulators for the treatment of cancer. Bringing together leaders in the field to utilize over three decades of p53 biology, PMV Pharma combines unique biological understanding with pharmaceutical development focus.

MDClone

Series B in 2019
MDClone Ltd. is a company that specializes in software designed to analyze medical records while ensuring patient privacy. Founded in 2016 and based in Beersheba, Israel, MDClone's platform generates synthetic medical records for fictitious patients. This innovative approach allows researchers to study disease behavior, medical practices, and various healthcare dynamics without exposing actual patient data. The platform creates fictitious individuals with unique characteristics, preserving essential relationships between them, thus maintaining the integrity of medical information while safeguarding privacy. By enabling health organizations to harness the value of their data assets, MDClone significantly enhances the ways medical information is gathered, analyzed, and utilized in research and service delivery.

Foamix

Post in 2019
Foamix Pharmaceuticals Inc. a pharmaceutical company, engages in development and commercialization of proprietary, innovative, and differentiated topical drugs for dermatological conditions. It offers Molecule Stabilizing Technology (MST) platform. The company was incorporated in 2014 and is based in Bridgewater, New Jersey. Foamix Pharmaceuticals Inc. operates as a subsidiary of Menlo Therapeutics Inc.

Acutus Medical

Debt Financing in 2019
Acutus Medical, Inc. is an arrhythmia management company that specializes in developing medical technologies for diagnosing and treating complex cardiac arrhythmias. Founded in 2011 and based in Carlsbad, California, the company designs, manufactures, and markets a comprehensive range of tools for catheter-based ablation procedures. Its product offerings include advanced imaging and mapping systems, such as the AcQMap console and workstation, along with diagnostic catheters and therapeutic devices like ablation catheters and robotic navigation systems. Acutus Medical's innovative platform enables electrophysiologists to visualize the heart's activation patterns, facilitating more effective treatment of arrhythmias. The company collaborates with medical scientists and engineers in the U.S. and Europe to enhance its product development and provides solutions to hospitals and electrophysiologists globally.

Acutus Medical

Series D in 2019
Acutus Medical, Inc. is an arrhythmia management company that specializes in developing medical technologies for diagnosing and treating complex cardiac arrhythmias. Founded in 2011 and based in Carlsbad, California, the company designs, manufactures, and markets a comprehensive range of tools for catheter-based ablation procedures. Its product offerings include advanced imaging and mapping systems, such as the AcQMap console and workstation, along with diagnostic catheters and therapeutic devices like ablation catheters and robotic navigation systems. Acutus Medical's innovative platform enables electrophysiologists to visualize the heart's activation patterns, facilitating more effective treatment of arrhythmias. The company collaborates with medical scientists and engineers in the U.S. and Europe to enhance its product development and provides solutions to hospitals and electrophysiologists globally.

Apollomics

Series B in 2019
Apollomics is a developer of oncology therapeutics intend to harness the immune system and targeting specific molecular pathways.The company's therapeutics target the growth and proliferation of cancer cells and offer an oral c-Met inhibitor that restores the body's immune system to recognize and kill cancer cells, enabling clients to treat their patients in an enhanced way.

Third Harmonic Bio

Series A in 2019
Third Harmonic Bio is a clinical-stage biopharmaceutical company dedicated to developing innovative treatments for severe allergies and inflammation. The company is focused on creating first-in-class oral small-molecule inhibitors targeting the KIT receptor, which plays a crucial role in the survival and function of mast cells—key immune cells involved in allergic responses. Its lead product candidate, THB001, is designed to provide selective inhibition of KIT, while another candidate, THB335, aims to address multiple mast cell-driven inflammatory diseases affecting the skin, respiratory system, and gastrointestinal tract. Through its research and development efforts, Third Harmonic Bio seeks to advance the management of inflammatory diseases, enhancing patient outcomes and quality of life.

Bellus Health

Post in 2018
Bellus Health Inc. is a clinical-stage biopharmaceutical company headquartered in Laval, Canada, focused on developing therapeutics for chronic cough and other hypersensitization disorders. Its lead drug candidate, BLU-5937, is an oral small molecule antagonist of the P2X3 receptor, currently undergoing Phase II clinical trials for chronic cough and chronic pruritus. Additionally, the company is advancing KIACTA™, a novel treatment for AA amyloidosis and sarcoidosis, both rare diseases affecting renal and pulmonary functions, respectively. KIACTA™ is in the data review stage following a Phase 3 study. Bellus Health is also developing Shigamab™, an antibody treatment for Hemolytic Uremic Syndrome caused by Shiga toxin-producing E. coli, with pre-clinical studies in progress. Furthermore, the company has a research-stage project aimed at treating AL amyloidosis, a condition characterized by the accumulation of amyloid proteins in various organs. Bellus Health is dedicated to addressing unmet medical needs through its innovative drug development pipeline.

Modis Therapeutics

Series A in 2018
Modis Therapeutics, Inc. is a biopharmaceutical company focused on developing disease-modifying therapies for rare genetic diseases with significant unmet medical needs. The company, based in Oakland, California, was incorporated in 2016 and is a subsidiary of Zogenix, Inc. Modis Therapeutics is advancing its lead therapy, MT1621, which aims to restore mitochondrial DNA replication fidelity. This therapeutic candidate is specifically designed to address thymidine kinase 2 deficiency (TK2d), an inherited mitochondrial disorder. By improving nucleotide balance, increasing mitochondrial DNA copy number, and enhancing cell function, Modis Therapeutics aims to provide meaningful treatment options that can prolong the lives of affected patients.

TigerConnect

Debt Financing in 2018
TigerConnect is a healthcare communication platform designed to enhance collaboration among healthcare professionals, patients, and care providers. Founded in 2010 and based in Santa Monica, California, the company offers real-time mobile messaging that combines a user-friendly experience with robust security and privacy features. Trusted by over 4,000 healthcare organizations, TigerConnect processes more than 10 million messages daily and boasts a 99.99% uptime. The platform facilitates effective communication and workflow integration with critical hospital systems, ultimately aiming to improve productivity, reduce costs, and enhance patient outcomes. TigerConnect's commitment to client success is evident in its comprehensive support services, which assist organizations in optimizing communication workflows.

Avedro

Series F in 2018
Avedro, Inc. is an ophthalmic pharmaceutical and medical device company that specializes in developing and commercializing products for treating corneal disorders, particularly those associated with corneal weakness. The company's primary offering is the Avedro Corneal Remodeling platform, which includes the KXL and Mosaic systems, designed to deliver ultraviolet A (UVA) light alongside various single-use riboflavin drug formulations. This platform addresses corneal ectatic disorders and refractive conditions, with specific applications in treating progressive keratoconus and corneal ectasia following refractive surgery. Avedro also offers the Keraflex procedure, a non-invasive technique for corneal reshaping that preserves corneal integrity. The company's products are primarily marketed to ophthalmologists, hospitals, and ambulatory surgery centers both in the United States and internationally through a network of distributors. Avedro, which was incorporated in 2002 and is headquartered in Waltham, Massachusetts, operates as a subsidiary of Glaukos Corporation.

Foamix

Post in 2018
Foamix Pharmaceuticals Inc. a pharmaceutical company, engages in development and commercialization of proprietary, innovative, and differentiated topical drugs for dermatological conditions. It offers Molecule Stabilizing Technology (MST) platform. The company was incorporated in 2014 and is based in Bridgewater, New Jersey. Foamix Pharmaceuticals Inc. operates as a subsidiary of Menlo Therapeutics Inc.
Asian Institute of Medical Sciences is a 425 bedded super specialty hospital in Delhi NCR, India which is dedicated to provide accessible, affordable and best available healthcare services in India. Accredited by NABH and NABL, Asian Hospital Faridabad provides preventive, diagnostic, therapeutic, rehabilitative, palliative and supportive services all under one roof and is designed to meet patient care and research requirements of the new millennium. Asian Institute of Medical Sciences offers comprehensive multi-specialty tertiary care facilities through its 14 centres of excellence. - ASIAN CANCER CENTRE - ASIAN CENTRE FOR BONE MARROW TRANSPLANT - ASIAN HEART CENTRE - ASIAN CENTRE FOR ADVANCED SURGERY - ASIAN CENTRE FOR NEUROLOGY AND NEUROSURGERY - ASIAN CENTRE FOR UROLOGY AND KIDNEY TRANSPLANT - ASIAN CENTRE FOR RENAL DISEASES - ASIAN CENTRE FOR BONE AND JOINTS - ASIAN CENTRE FOR ADVANCED IMAGING - ASIAN CENTRE FOR GASTROENTEROLOGY - ASIAN CENTRE FOR MOTHER AND CHILD - ASIAN CENTRE FOR BARIATRIC & METABOLIC SURGERY - ASIAN CENTRE FOR AESTHETIC SURGERY & MEDICINE - ASIAN IVF CENTRE

MDClone

Series A in 2018
MDClone Ltd. is a company that specializes in software designed to analyze medical records while ensuring patient privacy. Founded in 2016 and based in Beersheba, Israel, MDClone's platform generates synthetic medical records for fictitious patients. This innovative approach allows researchers to study disease behavior, medical practices, and various healthcare dynamics without exposing actual patient data. The platform creates fictitious individuals with unique characteristics, preserving essential relationships between them, thus maintaining the integrity of medical information while safeguarding privacy. By enabling health organizations to harness the value of their data assets, MDClone significantly enhances the ways medical information is gathered, analyzed, and utilized in research and service delivery.

TytoCare

Series C in 2018
TytoCare Ltd. is a healthcare technology company that develops handheld devices and applications for on-demand medical examinations and remote diagnoses. Founded in 2012 and based in Netanya, Israel, with an office in New York, the company offers three main telehealth products: TytoHome for consumers, TytoPro for professionals, and TytoClinic for remote care settings. These tools enable users to conduct self-examinations of various health conditions, such as ear infections, respiratory issues, and abdominal pain, by assessing the heart, lungs, skin, throat, ears, and body temperature. The platform facilitates virtual consultations by connecting patients with healthcare professionals, allowing for diagnosis and prescriptions as needed. TytoCare's technology incorporates a cloud-based data repository, analytics, and machine learning algorithms to enhance user experience and diagnostic accuracy. The company has established a strategic partnership with Novant Health to further its mission of making healthcare accessible and convenient.

Vivimed Labs

Post in 2018
Vivimed Labs has metamorphosed from a domestic small, entrepreneurial family-operated business to a globally renowned supplier of niche molecules and formulations across Healthcare, Pharmaceuticals and Specialty Chemicals consumers in nearly 50 countries.Driven by our philosophy of using chemistry as a base to create ingredients which touch human life on a day to day basis, Vivimed Labs delivers world-class products across the various segments They serve.

Chemomab

Series B in 2017
ChemomAb Ltd. is a clinical-stage biopharmaceutical company based in Tel Aviv, Israel, founded in 2011. The company focuses on developing proprietary monoclonal antibodies aimed at treating autoimmune, inflammatory, and fibrotic diseases, including rare conditions. Its leading therapeutic candidate, CM-101, has undergone extensive pre-clinical testing in animal models that simulate human disorders, demonstrating promising safety and efficacy along with a novel mechanism of action. Through its innovative approach, ChemomAb aims to address unmet medical needs in immune-mediated and fibrotic disorders.

TELA Bio

Private Equity Round in 2017
TELA Bio, Inc. is a medical technology company based in Malvern, Pennsylvania, that specializes in the design, development, and marketing of tissue reinforcement materials aimed at addressing unmet needs in soft tissue reconstruction. Founded in 2012, the company offers a range of products under the OviTex brand, including OviTex Reinforced Tissue Matrix for hernia repair and abdominal wall reconstruction, as well as OviTex PRS Reinforced Tissue Matrix for plastic and reconstructive surgery. Additionally, TELA Bio provides OviTex products specifically designed for laparoscopic and robotic surgical procedures, which utilize a sterile reinforced tissue matrix derived from ovine rumen with polypropylene fiber. The company's marketing efforts are primarily conducted through a direct sales force operating mainly in the United States.

Gemini Therapeutics

Series A in 2017
Gemini Therapeutics, Inc. is a precision medicine company established in 2015 and based in Cambridge, Massachusetts. The company specializes in developing therapies for patients with dry age-related macular degeneration (AMD) and related rare genetic diseases. Gemini's approach focuses on addressing genetically-defined conditions by creating therapeutic candidates that target specific molecular abnormalities prevalent in patients with significant clinical needs. Their diverse pipeline features a range of innovative treatment modalities, including monoclonal antibodies, recombinant proteins, and gene therapies. The company has secured funding from prominent life science investors and collaborates with academic institutions globally to advance its mission of delivering potentially first-in-class therapeutics.

Azura Ophthalmics

Series B in 2017
Azura Ophthalmics is a clinical-stage company focused on developing innovative treatments for Meibomian Gland Dysfunction (MGD), a leading cause of dry eye disease (DED). By addressing the underlying causes of MGD, Azura aims to improve the health and quality of life for millions affected by this and other ocular surface diseases, where effective treatment options are often limited. The company is advancing a unique portfolio of compounds in conjunction with a novel drug delivery platform, enabling healthcare professionals to better manage these conditions. Based in Tel Aviv-Yafo, Israel, Azura also has operational presence in Australia and the United States, supported by a management team with a strong track record in the development and commercialization of novel ocular therapies.

Vivimed Labs

Post in 2017
Vivimed Labs has metamorphosed from a domestic small, entrepreneurial family-operated business to a globally renowned supplier of niche molecules and formulations across Healthcare, Pharmaceuticals and Specialty Chemicals consumers in nearly 50 countries.Driven by our philosophy of using chemistry as a base to create ingredients which touch human life on a day to day basis, Vivimed Labs delivers world-class products across the various segments They serve.

Sonendo

Private Equity Round in 2017
Sonendo, Inc. is a medical technology company that focuses on advancing dental care through innovative devices for root canal therapy. Based in Laguna Hills, California, Sonendo has developed the GentleWave® System, which enhances the cleaning and disinfection of tooth canals, improving clinical outcomes and efficiency compared to traditional methods. The company operates primarily through two segments: the Product segment, which includes sales of the GentleWave System and its related instruments, and the Software segment, which encompasses TDO® Software—widely recognized as a leading practice management solution for endodontics. Since its incorporation in 2006, Sonendo has aimed to transform dentistry by promoting effective treatments that preserve tooth structure and enhance patient care.

ARMO BioSciences

Series C in 2017
ARMO Biosciences is a biotechnology company that develops immune modulatory biologic therapeutics. The company is based in Redwood City, California.

MobileODT

Series B in 2017
MobileODT Ltd specializes in developing optical diagnostic devices and software focused on early cancer detection, particularly cervical cancer. The company's flagship product, the EVA COLPO, is a portable, internet-connected colposcope that is FDA-cleared and designed for ease of use. MobileODT also offers EVA SANE, a secure platform for managing patient information, and EVA WELL, a digital visualization tool for gynecologic exams. Their offerings include a mobile application for remote image capture and patient tracking, along with a cloud-based portal for collaboration and reporting. In addition, the company provides tools for documenting violence and abuse and plans to expand its product line to cover other medical areas such as ENT and dermatology. Established in 2012 and headquartered in Tel Aviv, Israel, with an office in New York, MobileODT has gained recognition in various markets, particularly the United States, where it is becoming a standard for visual diagnostics in healthcare settings.

Mitoconix

Series A in 2017
Mitoconix Bio Ltd develops a novel strategy to improve mitochondrial health as a disease modifying therapeutic for neurodegenerative diseases. The company was founded in 2016 and is based in Jerusalem, Israel.

Synlogic

Series C in 2017
Synlogic, Inc. is a clinical-stage biopharmaceutical company based in Cambridge, Massachusetts, specializing in the discovery and development of synthetic biotic medicines aimed at treating metabolic, inflammatory, and cancer-related diseases. The company’s lead therapeutic program, SYNB1618, is an oral therapy currently in Phase I/IIa clinical trials for the treatment of phenylketonuria. Additionally, Synlogic is developing SYNB1891, an intratumoral synthetic biotic medicine that is undergoing Phase I clinical trials for the treatment of solid tumors and lymphoma. The company is also exploring synthetic biotics for more common conditions, including inflammatory bowel disease and secondary hyperoxaluria. Synlogic has established a collaboration with Ginkgo Bioworks to advance its development of these innovative therapies.

Xtant Medical

Post in 2017
Xtant Medical is a medical technology company specializing in the development, manufacturing, and marketing of regenerative medicine products and medical devices for orthopedic and neurological applications. The company offers a diverse portfolio of biomaterial products, including OsteoSponge, OsteoSelect DBM Putty, and OsteoWrap, which facilitate bone healing and fusion. Additionally, Xtant Medical provides a range of allografts designed for various surgical applications, such as anterior cruciate ligament repairs and spinal surgeries. The company's spinal implant systems support complex spine procedures and are utilized by orthopedic and neurosurgeons. Headquartered in Belgrade, Montana, Xtant Medical operates primarily in the United States and has established a significant presence in the orthopedic and neurosurgery markets through an extensive network of sales representatives and health system contracts. Formed through the merger of Bacterin International and X-spine Systems, Xtant Medical is positioned as a competitive player in the medical device industry, emphasizing innovation and comprehensive solutions for surgical needs.

Guardant Health

Series E in 2017
Guardant Health, Inc. is a precision oncology company based in Redwood City, California, specializing in liquid biopsy tests and analytics for cancer detection and treatment. The company provides advanced testing solutions, including Guardant360, a molecular diagnostic test that analyzes numerous cancer-related genes, and GuardantOMNI, which offers a comprehensive gene panel for immuno-oncology research. Additionally, Guardant Health has developed LUNAR-1 for detecting minimal residual disease in cancer survivors and is working on LUNAR-2 for early cancer detection in high-risk individuals. The company also supports biopharmaceutical companies and medical institutions by offering companion diagnostic development, clinical trial referrals, and liquid biopsy testing services. Guardant Health's innovations aim to address unmet needs in oncology and enhance patient health through advanced technology and research collaborations. The company was incorporated in 2011 and continues to lead in liquid-based cancer testing for both clinical and research applications.

Avedro

Venture Round in 2017
Avedro, Inc. is an ophthalmic pharmaceutical and medical device company that specializes in developing and commercializing products for treating corneal disorders, particularly those associated with corneal weakness. The company's primary offering is the Avedro Corneal Remodeling platform, which includes the KXL and Mosaic systems, designed to deliver ultraviolet A (UVA) light alongside various single-use riboflavin drug formulations. This platform addresses corneal ectatic disorders and refractive conditions, with specific applications in treating progressive keratoconus and corneal ectasia following refractive surgery. Avedro also offers the Keraflex procedure, a non-invasive technique for corneal reshaping that preserves corneal integrity. The company's products are primarily marketed to ophthalmologists, hospitals, and ambulatory surgery centers both in the United States and internationally through a network of distributors. Avedro, which was incorporated in 2002 and is headquartered in Waltham, Massachusetts, operates as a subsidiary of Glaukos Corporation.

SteadyMed Ltd.

Post in 2017
SteadyMed Ltd. is a medical-device company pursuing innovative devices for delivering injectable therapeutic drugs for pain relief, diabetes and other chronic conditions. The company's products are pre-filled drug-infusion patches that will be sold in conjunction with a series of pharma and device companies. Specific applications of the device will be tailored in accordance with the requirements of the company's partners.

PMV Pharmaceuticals

Series B in 2017
PMV Pharma is developing first-in-class p53 and p53 pathway modulators for the treatment of cancer. Bringing together leaders in the field to utilize over three decades of p53 biology, PMV Pharma combines unique biological understanding with pharmaceutical development focus.

ViewRay

Post in 2017
ViewRay, Inc. specializes in the design, manufacture, and marketing of advanced radiation therapy systems, particularly the MRIdian system, which is the first MRI-guided radiation therapy technology that allows simultaneous imaging and treatment of cancer patients. This innovative system integrates MRI technology with radiation delivery and proprietary software, enabling clinicians to accurately locate, target, and track soft-tissue tumors during treatment. By providing real-time imaging, MRIdian enhances visibility of tumors, thus allowing for precise radiation delivery while minimizing exposure to surrounding healthy tissue. This capability addresses significant limitations of traditional external-beam radiation therapies and expands treatment options for patients who may not have been eligible for radiation therapy previously. ViewRay serves a diverse client base, including university hospitals, community hospitals, and freestanding cancer centers, through a direct sales force and distribution network. The company, founded in 2004 and headquartered in Oakwood, Ohio, has operations in the United States and several European countries.

ScPharmaceuticals

Series B in 2017
scPharmaceticals is creating innovative and important new therapeutic options by administering drugs subcutaneously using a convenient two component delivery system suitable for patient self-administration.In February 2013 scPharmaceuticals was formed to continue the groundbreaking work of SpringLeaf Therapeutics, a Boston area company that started in 2007. scPharmaceuticals targets the untapped opportunity of treating patients with serious medical conditions with a convenient safe and comfortable subcutaneous administration of a drug. This is therapeutically equivalent to intravenous administration while avoiding the cost, burden and risks associated with intravenous administration.

Sonendo

Series E in 2016
Sonendo, Inc. is a medical technology company that focuses on advancing dental care through innovative devices for root canal therapy. Based in Laguna Hills, California, Sonendo has developed the GentleWave® System, which enhances the cleaning and disinfection of tooth canals, improving clinical outcomes and efficiency compared to traditional methods. The company operates primarily through two segments: the Product segment, which includes sales of the GentleWave System and its related instruments, and the Software segment, which encompasses TDO® Software—widely recognized as a leading practice management solution for endodontics. Since its incorporation in 2006, Sonendo has aimed to transform dentistry by promoting effective treatments that preserve tooth structure and enhance patient care.

Augmedix

Venture Round in 2016
Augmedix, Inc. is a technology-driven company that specializes in remote medical documentation and real-time clinical support. Founded in 2012 and headquartered in San Francisco, California, Augmedix offers an application that transforms clinician-patient conversations into medical documentation, allowing healthcare providers to concentrate on patient care rather than electronic health record (EHR) data entry. The service utilizes wearable technology, including Google Glass and smartphones, to facilitate this process, enabling clinicians to review and finalize documentation seamlessly. Augmedix caters to both large healthcare organizations and individual practitioners, charging service fees for subscription to its documentation and support offerings. The company also has additional offices in Menlo Park, California, and Dhaka, Bangladesh.

Inspire Medical Systems

Series F in 2016
Inspire Medical Systems, Inc., a medical technology company, focuses on the development and commercialization of minimally invasive solutions for patients with obstructive sleep apnea (OSA). It offers Inspire system, a neurostimulation technology that provides a safe and effective treatment for moderate to severe OSA. The company also develops a novel, a closed-loop solution that continuously monitors a patient’s breathing and delivers mild hypoglossal nerve stimulation to maintain an open airway. Inspire Medical Systems, Inc. was founded in 2007 and is headquartered in Golden Valley, Minnesota.

Suraksha Diagnostics

Venture Round in 2016
Established in 1992 as Suraksha Diagnostics & Eye Centre (P) Ltd. in Kolkata, they started as one of the first diagnostic centers in Kolkata to provide all pathology and radiology services under one roof. This convenience, along with their unwavering commitment to accuracy and service, resulted in steady growth and popularity. Within 3 years they could confidently open a second Center at Siliguri, in North Bengal, which remains the largest such facility in the region, and today serves not only to patients from North Bengal, but also neighbouring States and countries. Since then they have grown steadily across Bengal, Bihar, and Delhi NCR.

Chemomab

Series A in 2016
ChemomAb Ltd. is a clinical-stage biopharmaceutical company based in Tel Aviv, Israel, founded in 2011. The company focuses on developing proprietary monoclonal antibodies aimed at treating autoimmune, inflammatory, and fibrotic diseases, including rare conditions. Its leading therapeutic candidate, CM-101, has undergone extensive pre-clinical testing in animal models that simulate human disorders, demonstrating promising safety and efficacy along with a novel mechanism of action. Through its innovative approach, ChemomAb aims to address unmet medical needs in immune-mediated and fibrotic disorders.
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