OrbiMed

Founded in 1989, OrbiMed is a New York-based healthcare-dedicated investment firm managing approximately $5 billion in assets. It invests across the spectrum of healthcare companies, from private start-ups to large multinational corporations, focusing on biopharmaceuticals, life sciences, digital health, medical devices, and diagnostics sectors globally.

Roy Amariglio Ph.D

Principal

Mona Ashiya

Partner

David Bonita

General Partner

Sven Borho

Managing Partner

Evan Caplan

Principal

Sumona Chakraborty

Director

Nissim Darvish

Venture Partner

Iain Dukes

Venture Partner

Michael Eggenberg

Managing Director

Lars Enstrom

Managing Director

Robert Glassman

Venture Partner

Joshua Golomb

Partner, Public Equity

Rishi Gupta

Partner

Geoffrey Hsu

General Partner

Alexandria Huynh

Analyst

Mark Jelley

Managing Director

Chau Khuong

Partner

Kip Kitur

Senior Associate

Kevin Koch

Venture Partner

Dimitri Krainc

Venture Partner

Jonathan Lee

Analyst

Yifu Liu

Managing Director, Asia

Jonathan Mandelbaum

Senior Associate

John McGrath MD

Venture Partner

Anat Naschitz

Venture Partner

W. Carter Neild

Managing Partner

Anat Nursella

Venture Partner

Valerie Odegard Ph.D

Venture Partner

Topher Orr

Analyst

Trevor M. Polischuk

Public Equity Partner

Matthew Rizzo

Partner

William Sawyer

Partner

Michael B. Sheffery

Partner and Co-Founder

Natasha Shervani

Senior Associate

Jonathan Silverstein

Partner

Vivek Sivathanu

Senior Associate

Stephen Squinto

Partner

Charles Steinman

Analyst

C. Scotland Stevens

General Partner

Jim Sullivan

Venture Partner

Peter Thompson

Partner

Klaus Veitinger Ph.D

Venture Partner

Clive Wang

Director, Asia

Guowei Wang Ph.D

Senior Managing Director, Asia and Partner

Steven Wang

Partner

Iris Wang

Partner

David Wang

Partner and Senior Managing Director, Asia

Conrad Wang

Principal

Dimitrios Weedon

Managing Director

Matthew Wotiz

Principal

Stella Xing

Managing Director

Diyong Xu

Principal

Nate Yee

Vice President

Daniel Zhou

Managing Director, Asia

Past deals in Dental

vVardis

Venture Round in 2025
vVardis is a personal oral care brand offering professional dental products and consumer oral care solutions. Its proprietary CUROLOX® & WX Technology enhances overall health by improving oral hygiene, protecting teeth from decay, erosion, and sensitivity.

Arrail Dental International Group

Series E in 2021
Arrail Dental International Group is a premium private dental services provider in China operating a network of clinics offering endodontics, general dentistry, implants, orthodontics, pediatric dentistry, prosthodontics, and periodontics, along with hygiene, toothache treatment, restoration, whitening, and elderly teeth care, and online appointment services. Founded in 1998 and based in Beijing, it maintains clinics across major Chinese cities and positions itself as a platform for elite dentists worldwide. The business operates in two segments, Arrail Dental and Rytime Dental, with the latter contributing the majority of revenue.

Sonendo

Private Equity Round in 2020
Sonendo is a commercial-stage medical technology company that develops dental devices and software to save teeth. It markets the GentleWave System, a root canal therapy platform that cleans and disinfects the microscopic spaces within teeth without removing tooth structure, improving clinical outcomes and practice efficiency. The system includes a console and accessories and integrates with TDO Software, its endodontic practice management software that unifies imaging, practice management, referral reporting, CBCT imaging, and built-in communication with the GentleWave System. Founded in 2006 and based in Laguna Hills, California, Sonendo operates with two business segments: Product, comprising the GentleWave console and instruments, and Software, providing practice management licenses. The company aims to transform dentistry by saving teeth through sound science.

Sonendo

Private Equity Round in 2017
Sonendo is a commercial-stage medical technology company that develops dental devices and software to save teeth. It markets the GentleWave System, a root canal therapy platform that cleans and disinfects the microscopic spaces within teeth without removing tooth structure, improving clinical outcomes and practice efficiency. The system includes a console and accessories and integrates with TDO Software, its endodontic practice management software that unifies imaging, practice management, referral reporting, CBCT imaging, and built-in communication with the GentleWave System. Founded in 2006 and based in Laguna Hills, California, Sonendo operates with two business segments: Product, comprising the GentleWave console and instruments, and Software, providing practice management licenses. The company aims to transform dentistry by saving teeth through sound science.

Sonendo

Series E in 2016
Sonendo is a commercial-stage medical technology company that develops dental devices and software to save teeth. It markets the GentleWave System, a root canal therapy platform that cleans and disinfects the microscopic spaces within teeth without removing tooth structure, improving clinical outcomes and practice efficiency. The system includes a console and accessories and integrates with TDO Software, its endodontic practice management software that unifies imaging, practice management, referral reporting, CBCT imaging, and built-in communication with the GentleWave System. Founded in 2006 and based in Laguna Hills, California, Sonendo operates with two business segments: Product, comprising the GentleWave console and instruments, and Software, providing practice management licenses. The company aims to transform dentistry by saving teeth through sound science.

SI-BONE

Venture Round in 2016
SI-BONE, Inc. is a medical device company based in Santa Clara, California, that specializes in the development and commercialization of implantable devices for surgical treatment of sacropelvic anatomy. Founded in 2008, the company offers a range of patented titanium implants, including the iFuse system, which is designed for the minimally invasive fusion of the sacroiliac joint to alleviate dysfunction that leads to lower back pain. The iFuse implant procedure is noted for its reduced invasiveness and efficiency compared to traditional open fusion methods. In addition to the iFuse system, SI-BONE develops other products such as iFuse-3D, iFuse-TORQ, and iFuse Bedrock Granite, which address various conditions related to sacroiliac joint dysfunction, spinal deformity, and pelvic trauma. The company operates both in the United States and internationally.

sikka.ai

Series C in 2015
Sikka Software is a pioneering company in the retail healthcare market, offering a cloud-based business intelligence platform that leverages artificial intelligence and predictive analytics. Its award-winning single API platform is designed to support non-physician practices, including dentistry, veterinary care, optometry, chiropractic, orthodontic, and oral surgery. With 35,000 practice installations and connectivity to 96% of the retail healthcare market, Sikka Software enables healthcare providers to optimize their operations through a suite of applications that integrate various practice management and financial systems. The platform hosts 50 applications developed by numerous suppliers, including Fortune 500 companies, alongside four proprietary applications from Sikka. With a vision to create a real-time global platform that connects patients, providers, and suppliers, Sikka addresses a services market exceeding $260 billion annually. The Sikka ONE API was recognized with the Best Health API Award in 2019, highlighting its innovation and impact in the industry.

SI-BONE

Venture Round in 2015
SI-BONE, Inc. is a medical device company based in Santa Clara, California, that specializes in the development and commercialization of implantable devices for surgical treatment of sacropelvic anatomy. Founded in 2008, the company offers a range of patented titanium implants, including the iFuse system, which is designed for the minimally invasive fusion of the sacroiliac joint to alleviate dysfunction that leads to lower back pain. The iFuse implant procedure is noted for its reduced invasiveness and efficiency compared to traditional open fusion methods. In addition to the iFuse system, SI-BONE develops other products such as iFuse-3D, iFuse-TORQ, and iFuse Bedrock Granite, which address various conditions related to sacroiliac joint dysfunction, spinal deformity, and pelvic trauma. The company operates both in the United States and internationally.

Laxmi Dental

Venture Round in 2015
Laxmi Dental is a comprehensive dental products company offering a wide range of solutions for dental laboratories and offices. Their product portfolio includes metal-free restorations, porcelain-fused-to-metal crowns and bridges, implant prosthetics, removable appliances, aligners, and pediatric dental products.

Sonendo

Series D in 2014
Sonendo is a commercial-stage medical technology company that develops dental devices and software to save teeth. It markets the GentleWave System, a root canal therapy platform that cleans and disinfects the microscopic spaces within teeth without removing tooth structure, improving clinical outcomes and practice efficiency. The system includes a console and accessories and integrates with TDO Software, its endodontic practice management software that unifies imaging, practice management, referral reporting, CBCT imaging, and built-in communication with the GentleWave System. Founded in 2006 and based in Laguna Hills, California, Sonendo operates with two business segments: Product, comprising the GentleWave console and instruments, and Software, providing practice management licenses. The company aims to transform dentistry by saving teeth through sound science.

SI-BONE

Venture Round in 2014
SI-BONE, Inc. is a medical device company based in Santa Clara, California, that specializes in the development and commercialization of implantable devices for surgical treatment of sacropelvic anatomy. Founded in 2008, the company offers a range of patented titanium implants, including the iFuse system, which is designed for the minimally invasive fusion of the sacroiliac joint to alleviate dysfunction that leads to lower back pain. The iFuse implant procedure is noted for its reduced invasiveness and efficiency compared to traditional open fusion methods. In addition to the iFuse system, SI-BONE develops other products such as iFuse-3D, iFuse-TORQ, and iFuse Bedrock Granite, which address various conditions related to sacroiliac joint dysfunction, spinal deformity, and pelvic trauma. The company operates both in the United States and internationally.

Sonendo

Series C in 2013
Sonendo is a commercial-stage medical technology company that develops dental devices and software to save teeth. It markets the GentleWave System, a root canal therapy platform that cleans and disinfects the microscopic spaces within teeth without removing tooth structure, improving clinical outcomes and practice efficiency. The system includes a console and accessories and integrates with TDO Software, its endodontic practice management software that unifies imaging, practice management, referral reporting, CBCT imaging, and built-in communication with the GentleWave System. Founded in 2006 and based in Laguna Hills, California, Sonendo operates with two business segments: Product, comprising the GentleWave console and instruments, and Software, providing practice management licenses. The company aims to transform dentistry by saving teeth through sound science.

Sonendo

Series C in 2012
Sonendo is a commercial-stage medical technology company that develops dental devices and software to save teeth. It markets the GentleWave System, a root canal therapy platform that cleans and disinfects the microscopic spaces within teeth without removing tooth structure, improving clinical outcomes and practice efficiency. The system includes a console and accessories and integrates with TDO Software, its endodontic practice management software that unifies imaging, practice management, referral reporting, CBCT imaging, and built-in communication with the GentleWave System. Founded in 2006 and based in Laguna Hills, California, Sonendo operates with two business segments: Product, comprising the GentleWave console and instruments, and Software, providing practice management licenses. The company aims to transform dentistry by saving teeth through sound science.

Bonovo Orthopedics

Series C in 2010
Bonovo Orthopedics, Inc. is a provider of orthopedic implants and related products tailored for the Chinese healthcare market. Established in 2005 and headquartered in Scottsdale, Arizona, the company specializes in a wide range of products, including artificial discs, plates, and fixation systems for spinal treatments, as well as hip and knee joint systems and bone void fillers. Bonovo also offers minimally invasive surgical solutions, such as kyphoplasty systems for vertebral fracture management, along with a variety of surgical instruments and devices. With over 15 years of experience in manufacturing and distributing orthopedic products, Bonovo Orthopedics has built strong relationships with leading clinicians and hospitals, positioning itself as a key player in the Chinese orthopedic landscape. The company operates manufacturing facilities in Beijing and Shanghai, further supporting its commitment to providing advanced healthcare solutions.

Angel Aligner

Series A in 2010
Angel Aligner is a global provider of invisible orthodontic technology. It specializes in the production and sales of invisible braces, offering digital orthodontics solutions to dental professionals worldwide.
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