OrbiMed

OrbiMed is a healthcare-focused investment firm based in New York City, established in 1989. The firm specializes in providing a range of financing solutions, including bridge loans, senior debt, and structured debt capital for both commercial-stage public and private healthcare companies. OrbiMed invests across various sectors within the healthcare industry, such as pharmaceuticals, life sciences, digital health, medical devices, biopharmaceuticals, diagnostics, healthcare technology, and biotechnology. With approximately $5 billion in assets under management, OrbiMed aims to support a spectrum of healthcare companies, from early-stage ventures to established multinational corporations.

Roy Amariglio Ph.D

Principal

Mona Ashiya

Partner, Private Equity

David Bonita

General Partner

Sven Borho

Partner

Evan Caplan

Principal

Sumona Chakraborty

Director

Dina Chaya

Partner, Private Equity

Nissim Darvish

Venture Partner

Michael Eggenberg

Managing Director

Lars Enstrom

Managing Director

Joshua Golomb

Partner, Public Equity

Geoffrey Hsu

General Partner

Alexandria Huynh Ph.D

Analyst

Mark R. Jelley

Partner, Credit and Royalty

Kip Kitur Ph.D

Vice President, Private Equity

Dimitri Krainc

Venture Partner

Jonathan Lee

Partner

Yifu Liu

Managing Director, Asia

Jonathan Mandelbaum

Vice President, Private Equity

St John Donnie McGrath

Venture Partner

Anat Naschitz

Venture Partner

W. Carter Neild

Managing Partner

Anat Nursella

Venture Partner

Valerie Odegard

Venture Partner

Topher Orr

Partner, Public Equity

Trevor M. Polischuk

Public Equity Partner

Matthew S. Rizzo

General Partner

William Sawyer

Partner

Michael B. Sheffery

Partner and Co-Founder

Natasha Shervani

Vice President

Jonathan Silverstein

Executive Partner

Vivek Sivathanu Ph.D

Vice President, Private Equity

Charles Steinman

Analyst

C. Scotland Stevens

General Partner

Clive Wang

Director, Asia

Steven Wang

Partner

Iris Wang

Partner

David Wang

Partner and Senior Managing Director, Asia

Dimitrios Weedon

Managing Director

Matthew L. Wotiz

Principal

Stella Xing

Managing Director

Diyong Xu

Principal, Private Equity

Nate Yee

Principal

Jessica Zhang Ph.D

Senior Associate

Daniel Zhou

Managing Director, Asia

Guowei Wang Ph.D

Senior Managing Director, Asia and Partner

Past deals in Dental

vVardis

Venture Round in 2025
vVardis is a personal oral care brand founded by Dres Abivardi, focusing on innovative dental care technology aimed at eradicating tooth decay. The company offers two distinct product lines: a professional dental line featuring the bur-free anti-caries CURODONT™ technology, used by dentists, and an oral care line designed for consumers at home. This consumer line includes products such as toothpaste, toothbrushes, mouth spray, and a highlighter, all formulated with proprietary CUROLOX® and WX Technology. vVardis emphasizes sustainability by ensuring its products are clean, vegan, cruelty-free, and free from peroxide and parabens. The brand aims to establish itself as a comprehensive oral care powerhouse.

Arrail Dental

Series E in 2021
Arrail Dental International Group Co. Ltd. is a prominent dental services provider in China, specializing in a wide range of oral health care services. Founded in 1998 and headquartered in Beijing, the company operates numerous clinics in major cities, including Shanghai, Shenzhen, Guangzhou, and Tianjin. Arrail Dental offers various services, including endodontics, general dentistry, orthodontics, pediatric dentistry, implants, and periodontics, alongside treatments for toothache, restoration, whitening, and elderly dental care. The company emphasizes accessibility by providing online appointment services and has established a platform that connects elite dentists from around the world. With a focus on the premium private dental service market, Arrail Dental is well-positioned to cater to the needs of clients in both domestic and international markets.

Sonendo

Private Equity Round in 2020
Sonendo, Inc. is a medical technology company based in Laguna Hills, California, specializing in innovative solutions for root canal therapy. Founded in 2006, the company has developed the GentleWave System, a technology platform that enhances the cleaning and disinfection of tooth structures without compromising integrity. This system significantly improves clinical outcomes and practice efficiency compared to traditional root canal methods. In addition to its product offerings, Sonendo is the parent company of TDO Software, which provides widely used practice management software for endodontic professionals. The software integrates various functionalities, including imaging and communication tools, to streamline practice workflows. Through its focus on advanced dental technologies, Sonendo aims to address the global challenge of tooth decay, ultimately promoting better dental health.

Sonendo

Private Equity Round in 2017
Sonendo, Inc. is a medical technology company based in Laguna Hills, California, specializing in innovative solutions for root canal therapy. Founded in 2006, the company has developed the GentleWave System, a technology platform that enhances the cleaning and disinfection of tooth structures without compromising integrity. This system significantly improves clinical outcomes and practice efficiency compared to traditional root canal methods. In addition to its product offerings, Sonendo is the parent company of TDO Software, which provides widely used practice management software for endodontic professionals. The software integrates various functionalities, including imaging and communication tools, to streamline practice workflows. Through its focus on advanced dental technologies, Sonendo aims to address the global challenge of tooth decay, ultimately promoting better dental health.

Sonendo

Series E in 2016
Sonendo, Inc. is a medical technology company based in Laguna Hills, California, specializing in innovative solutions for root canal therapy. Founded in 2006, the company has developed the GentleWave System, a technology platform that enhances the cleaning and disinfection of tooth structures without compromising integrity. This system significantly improves clinical outcomes and practice efficiency compared to traditional root canal methods. In addition to its product offerings, Sonendo is the parent company of TDO Software, which provides widely used practice management software for endodontic professionals. The software integrates various functionalities, including imaging and communication tools, to streamline practice workflows. Through its focus on advanced dental technologies, Sonendo aims to address the global challenge of tooth decay, ultimately promoting better dental health.

SI-BONE

Venture Round in 2016
SI-BONE, Inc. is a medical device company based in Santa Clara, California, that specializes in the development and commercialization of implantable devices for surgical treatment of sacropelvic anatomy. Founded in 2008, the company offers a range of patented titanium implants, including the iFuse system, which is designed for the minimally invasive fusion of the sacroiliac joint to alleviate dysfunction that leads to lower back pain. The iFuse implant procedure is noted for its reduced invasiveness and efficiency compared to traditional open fusion methods. In addition to the iFuse system, SI-BONE develops other products such as iFuse-3D, iFuse-TORQ, and iFuse Bedrock Granite, which address various conditions related to sacroiliac joint dysfunction, spinal deformity, and pelvic trauma. The company operates both in the United States and internationally.

sikka.ai

Series C in 2015
Sikka Software is a pioneering company in the retail healthcare market, offering a cloud-based business intelligence platform that leverages artificial intelligence and predictive analytics. Its award-winning single API platform is designed to support non-physician practices, including dentistry, veterinary care, optometry, chiropractic, orthodontic, and oral surgery. With 35,000 practice installations and connectivity to 96% of the retail healthcare market, Sikka Software enables healthcare providers to optimize their operations through a suite of applications that integrate various practice management and financial systems. The platform hosts 50 applications developed by numerous suppliers, including Fortune 500 companies, alongside four proprietary applications from Sikka. With a vision to create a real-time global platform that connects patients, providers, and suppliers, Sikka addresses a services market exceeding $260 billion annually. The Sikka ONE API was recognized with the Best Health API Award in 2019, highlighting its innovation and impact in the industry.

SI-BONE

Venture Round in 2015
SI-BONE, Inc. is a medical device company based in Santa Clara, California, that specializes in the development and commercialization of implantable devices for surgical treatment of sacropelvic anatomy. Founded in 2008, the company offers a range of patented titanium implants, including the iFuse system, which is designed for the minimally invasive fusion of the sacroiliac joint to alleviate dysfunction that leads to lower back pain. The iFuse implant procedure is noted for its reduced invasiveness and efficiency compared to traditional open fusion methods. In addition to the iFuse system, SI-BONE develops other products such as iFuse-3D, iFuse-TORQ, and iFuse Bedrock Granite, which address various conditions related to sacroiliac joint dysfunction, spinal deformity, and pelvic trauma. The company operates both in the United States and internationally.

Laxmi Dental

Venture Round in 2015
Laxmi Dentistry operates a dental laboratory that specializes in providing a range of dental products and solutions for dental offices and laboratories. The company offers a variety of products, including zirconia, Emax, aligners, and implants, with a focus on metal-free restorations, porcelain fused to metal, implant prosthetics, and removable appliances. By integrating digital workflows in the design and manufacturing processes, Laxmi Dentistry enhances efficiency and predictability in dental restorations. This approach allows dentists to achieve improved quality in final restorations while reducing chairside time and the need for adjustments. Overall, Laxmi Dentistry aims to deliver effective treatments for oral and dental issues through innovative product offerings and streamlined processes.

Sonendo

Series D in 2014
Sonendo, Inc. is a medical technology company based in Laguna Hills, California, specializing in innovative solutions for root canal therapy. Founded in 2006, the company has developed the GentleWave System, a technology platform that enhances the cleaning and disinfection of tooth structures without compromising integrity. This system significantly improves clinical outcomes and practice efficiency compared to traditional root canal methods. In addition to its product offerings, Sonendo is the parent company of TDO Software, which provides widely used practice management software for endodontic professionals. The software integrates various functionalities, including imaging and communication tools, to streamline practice workflows. Through its focus on advanced dental technologies, Sonendo aims to address the global challenge of tooth decay, ultimately promoting better dental health.

SI-BONE

Venture Round in 2014
SI-BONE, Inc. is a medical device company based in Santa Clara, California, that specializes in the development and commercialization of implantable devices for surgical treatment of sacropelvic anatomy. Founded in 2008, the company offers a range of patented titanium implants, including the iFuse system, which is designed for the minimally invasive fusion of the sacroiliac joint to alleviate dysfunction that leads to lower back pain. The iFuse implant procedure is noted for its reduced invasiveness and efficiency compared to traditional open fusion methods. In addition to the iFuse system, SI-BONE develops other products such as iFuse-3D, iFuse-TORQ, and iFuse Bedrock Granite, which address various conditions related to sacroiliac joint dysfunction, spinal deformity, and pelvic trauma. The company operates both in the United States and internationally.

Sonendo

Series C in 2013
Sonendo, Inc. is a medical technology company based in Laguna Hills, California, specializing in innovative solutions for root canal therapy. Founded in 2006, the company has developed the GentleWave System, a technology platform that enhances the cleaning and disinfection of tooth structures without compromising integrity. This system significantly improves clinical outcomes and practice efficiency compared to traditional root canal methods. In addition to its product offerings, Sonendo is the parent company of TDO Software, which provides widely used practice management software for endodontic professionals. The software integrates various functionalities, including imaging and communication tools, to streamline practice workflows. Through its focus on advanced dental technologies, Sonendo aims to address the global challenge of tooth decay, ultimately promoting better dental health.

Sonendo

Series C in 2012
Sonendo, Inc. is a medical technology company based in Laguna Hills, California, specializing in innovative solutions for root canal therapy. Founded in 2006, the company has developed the GentleWave System, a technology platform that enhances the cleaning and disinfection of tooth structures without compromising integrity. This system significantly improves clinical outcomes and practice efficiency compared to traditional root canal methods. In addition to its product offerings, Sonendo is the parent company of TDO Software, which provides widely used practice management software for endodontic professionals. The software integrates various functionalities, including imaging and communication tools, to streamline practice workflows. Through its focus on advanced dental technologies, Sonendo aims to address the global challenge of tooth decay, ultimately promoting better dental health.

Bonovo Orthopedics

Series C in 2010
Bonovo Orthopedics, Inc. is a provider of orthopedic implants and related products tailored for the Chinese healthcare market. Established in 2005 and headquartered in Scottsdale, Arizona, the company specializes in a wide range of products, including artificial discs, plates, and fixation systems for spinal treatments, as well as hip and knee joint systems and bone void fillers. Bonovo also offers minimally invasive surgical solutions, such as kyphoplasty systems for vertebral fracture management, along with a variety of surgical instruments and devices. With over 15 years of experience in manufacturing and distributing orthopedic products, Bonovo Orthopedics has built strong relationships with leading clinicians and hospitals, positioning itself as a key player in the Chinese orthopedic landscape. The company operates manufacturing facilities in Beijing and Shanghai, further supporting its commitment to providing advanced healthcare solutions.

Angelalign

Series A in 2010
Angelalign Technology Inc is a global provider of invisible orthodontic solutions, specializing in clear aligner treatment. The company focuses on manufacturing, marketing, and delivering comprehensive treatment planning services for dental professionals. Angelalign's innovative technology includes a self-developed digital orthodontics platform that supports dentists and orthodontists throughout the entire treatment process, from case assessment to final design. By offering digitally-assisted tools, Angelalign enhances the efficiency and effectiveness of orthodontic care, contributing to improved patient outcomes in clear aligner therapy.
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