OrbiMed

Founded in 1989, OrbiMed is a New York-based healthcare-dedicated investment firm managing approximately $5 billion in assets. It invests across the spectrum of healthcare companies, from private start-ups to large multinational corporations, focusing on biopharmaceuticals, life sciences, digital health, medical devices, and diagnostics sectors globally.

Roy Amariglio Ph.D

Principal

Mona Ashiya

Partner

David Bonita

General Partner

Sven Borho

Managing Partner

Evan Caplan

Principal

Sumona Chakraborty

Director

Nissim Darvish

Venture Partner

Iain Dukes

Venture Partner

Michael Eggenberg

Managing Director

Lars Enstrom

Managing Director

Robert Glassman

Venture Partner

Joshua Golomb

Partner, Public Equity

Rishi Gupta

Partner

Geoffrey Hsu

General Partner

Alexandria Huynh

Analyst

Sam Isaly

Founder and Chairman Emeritus

Mark Jelley

Managing Director

Chau Khuong

Partner

Kip Kitur

Senior Associate

Kevin Koch

Venture Partner

Dimitri Krainc

Venture Partner

Jonathan Lee

Analyst

Yifu Liu

Managing Director, Asia

Jonathan Mandelbaum

Senior Associate

John McGrath MD

Venture Partner

Anat Naschitz

Venture Partner

W. Carter Neild

Managing Partner

Anat Nursella

Venture Partner

Valerie Odegard Ph.D

Venture Partner

Topher Orr

Analyst

Trevor M. Polischuk

Public Equity Partner

Matthew Rizzo

Partner

William Sawyer

Partner

Michael B. Sheffery

Partner and Co-Founder

Natasha Shervani

Senior Associate

Jonathan Silverstein

Partner

Vivek Sivathanu

Senior Associate

Stephen Squinto

Partner

Charles Steinman

Analyst

C. Scotland Stevens

General Partner

Jim Sullivan

Venture Partner

Peter Thompson

Partner

Clive Wang

Director, Asia

Steven Wang

Partner

Iris Wang

Partner

David Wang

Partner and Senior Managing Director, Asia

Conrad Wang

Principal

Dimitrios Weedon

Managing Director

Matthew Wotiz

Principal

Stella Xing

Managing Director

Diyong Xu

Principal

Nate Yee

Vice President

Daniel Zhou

Managing Director, Asia

Guowei Wang Ph.D

Senior Managing Director, Asia and Partner

Past deals in Lyon

Poxel

Post in 2024
Poxel is a biopharmaceutical company based in Lyon, France, focused on developing innovative drugs for metabolic diseases, with a primary emphasis on type 2 diabetes and non-alcoholic steatohepatitis (NASH). Founded in 2009, Poxel's lead product is Imeglimin, an oral anti-diabetic candidate in Phase III clinical development that targets key organs affected by diabetes, such as the pancreas, liver, and muscles. The company is also advancing PXL770, an adenosine monophosphate-activated protein kinase enzyme in Phase IIa clinical trials for treating chronic metabolic diseases like NASH. Additionally, Poxel has licensing agreements for PXL007 (EYP001), an FXR agonist in Phase I study for hepatitis B and NASH, and PXL065, a mitochondrial pyruvate carrier inhibitor in Phase I clinical trials for NASH.

ENYO Pharma

Series C in 2024
ENYO Pharma SA is a clinical-stage biopharmaceutical company based in Lyon, France, founded in 2014 by scientists from the Infectiology Research Center. The company focuses on drug discovery and development for the treatment of acute and chronic viral infections, utilizing a unique platform to identify intracellular therapeutic targets and molecules. ENYO Pharma is developing a pipeline of drug candidates addressing various indications, including hepatitis B virus, nonalcoholic steatohepatitis, and oncology. Its lead compound, EYP001, is designed to modulate specific nuclear receptors, aiming to reduce viral reservoirs and inhibit harmful viral protein expression. The company is also advancing EYP002 through preclinical studies. ENYO Pharma collaborates closely with established research institutions and aims to conduct its molecules into Phase II clinical trials, striving to become a global leader in antiviral therapeutics.

ENYO Pharma

Series B in 2018
ENYO Pharma SA is a clinical-stage biopharmaceutical company based in Lyon, France, founded in 2014 by scientists from the Infectiology Research Center. The company focuses on drug discovery and development for the treatment of acute and chronic viral infections, utilizing a unique platform to identify intracellular therapeutic targets and molecules. ENYO Pharma is developing a pipeline of drug candidates addressing various indications, including hepatitis B virus, nonalcoholic steatohepatitis, and oncology. Its lead compound, EYP001, is designed to modulate specific nuclear receptors, aiming to reduce viral reservoirs and inhibit harmful viral protein expression. The company is also advancing EYP002 through preclinical studies. ENYO Pharma collaborates closely with established research institutions and aims to conduct its molecules into Phase II clinical trials, striving to become a global leader in antiviral therapeutics.
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