New Enterprise Associates

Fire1 is a Dublin-based company dedicated to developing innovative therapeutic devices aimed at enhancing the quality of life for heart failure patients. The company has created a remote monitoring system that delivers real-time patient data and insights to healthcare providers. This technology facilitates the early detection of complications associated with heart failure, allowing for proactive interventions and ultimately leading to improved patient outcomes. Through its focus on remote monitoring, Fire1 seeks to transform the management of heart failure and support better health management for patients.

Strive Health, LLC is a company focused on providing comprehensive solutions for chronic kidney disease. Founded in 2018 and based in Denver, Colorado, Strive Health operates dialysis centers and employs advanced predictive analytics to enhance patient care. The company offers a high-touch, technology-enabled clinical model that supports patients throughout their healthcare journey, from primary care engagement to dialysis treatment. By utilizing comparative and predictive data, Strive Health aims to identify at-risk patients and transform the management of kidney disease, promoting earlier intervention and increasing the adoption of home dialysis. This innovative approach not only improves patient outcomes but also seeks to reduce inpatient utilization, ultimately enhancing the overall experience for individuals dealing with chronic kidney conditions.

Fire1 is a Dublin-based company dedicated to developing innovative therapeutic devices aimed at enhancing the quality of life for heart failure patients. The company has created a remote monitoring system that delivers real-time patient data and insights to healthcare providers. This technology facilitates the early detection of complications associated with heart failure, allowing for proactive interventions and ultimately leading to improved patient outcomes. Through its focus on remote monitoring, Fire1 seeks to transform the management of heart failure and support better health management for patients.

Everside Health is a direct primary care provider founded in 2010 and based in Denver, Colorado. The company offers a range of services, including biometric screenings, health risk assessments, lifestyle coaching, and acute care, catering to patients across the nation. Everside's healthcare delivery model is data-driven and patient-centric, focusing on convenient on-site, near-site, and virtual care options. By aligning incentives among patients, physicians, and benefit providers, Everside aims to enhance patient engagement and overall health while simultaneously reducing the total cost of care.

Pager, Inc. is a company that operates an on-demand service platform designed to connect patients with healthcare services in various settings including homes, offices, and hotels. The company offers a mobile application that facilitates access to urgent care for a range of conditions such as infections, respiratory issues, and allergies. In addition to its core services, Pager provides nurse chat, teleconsultation, screening, vaccination, and prescription delivery. The company's mission focuses on improving healthcare accessibility, lowering costs, and simplifying care navigation through a flexible platform that integrates artificial intelligence and service teams. Amidst its extensive offerings, Pager supports over 15 million individuals across the United States and Latin America, enabling coordinated care that enhances patient engagement and decision-making. Incorporated in 2013 and headquartered in New York, Pager was previously known as techCare, Inc. before rebranding in 2014.

AllyAlign Health, Inc. is a care management company that specializes in supporting patients with chronic and complex medical conditions. Founded in 2013 and headquartered in Glen Allen, Virginia, the company operates an advanced care management platform that facilitates real-time, collaborative care across various healthcare settings. This platform connects patients with care teams and integrates essential health information, care plans, and benefits details, empowering users to make informed care decisions. It offers mobile and web-based access, allowing patients and their families to view, share, create, and update information conveniently from home or from afar. The company's central database is HIPAA compliant and consolidates data from diverse sources, including electronic health records, lab tests, and clinical systems, ensuring comprehensive and meaningful clinical insights through semantic data modeling.

Collective Health is a health benefits platform that integrates various medical, dental, vision, and pharmacy services into a cohesive solution aimed at simplifying healthcare for employees and their families. The company’s cloud-based platform streamlines the administration of health plans through a single portal, offering clear guidance, live concierge support, and digital tools for managing care. By reducing the administrative burden associated with health benefits, Collective Health enhances the member experience and aids organizations in controlling costs while improving health outcomes. Headquartered in San Francisco, California, the company also has offices in Chicago, Illinois, and Lehi, Utah.

Strive Health, LLC is a company focused on providing comprehensive solutions for chronic kidney disease. Founded in 2018 and based in Denver, Colorado, Strive Health operates dialysis centers and employs advanced predictive analytics to enhance patient care. The company offers a high-touch, technology-enabled clinical model that supports patients throughout their healthcare journey, from primary care engagement to dialysis treatment. By utilizing comparative and predictive data, Strive Health aims to identify at-risk patients and transform the management of kidney disease, promoting earlier intervention and increasing the adoption of home dialysis. This innovative approach not only improves patient outcomes but also seeks to reduce inpatient utilization, ultimately enhancing the overall experience for individuals dealing with chronic kidney conditions.

Eargo, Inc. is a consumer-focused medical device company specializing in the design and sale of hearing aids for individuals with hearing loss in the United States. Founded in 2010 and headquartered in San Jose, California, Eargo offers innovative, rechargeable hearing aids that can be controlled via smartphone, enhancing user convenience. The company provides online hearing screenings and virtual support, eliminating the need for in-person consultations. By adopting a direct-to-consumer model, Eargo aims to make hearing aids more accessible and reduce the social stigma often associated with them. Its user-centric approach addresses the common challenges of traditional hearing aid adoption, including cost and accessibility, thereby improving the quality of life for those with hearing difficulties.

Tempus, established in 2015 and based in Chicago, Illinois, is a technology company specializing in precision medicine. It develops a comprehensive library of molecular and clinical data, along with an operating system that makes this information accessible and useful for patients, physicians, and researchers. Tempus offers services such as genomic sequencing, clinical data restructuring, and biological modeling, enabling real-time data-driven decisions for personalized patient care and facilitating the discovery of optimized therapeutic options.

Pager, Inc. is a company that operates an on-demand service platform designed to connect patients with healthcare services in various settings including homes, offices, and hotels. The company offers a mobile application that facilitates access to urgent care for a range of conditions such as infections, respiratory issues, and allergies. In addition to its core services, Pager provides nurse chat, teleconsultation, screening, vaccination, and prescription delivery. The company's mission focuses on improving healthcare accessibility, lowering costs, and simplifying care navigation through a flexible platform that integrates artificial intelligence and service teams. Amidst its extensive offerings, Pager supports over 15 million individuals across the United States and Latin America, enabling coordinated care that enhances patient engagement and decision-making. Incorporated in 2013 and headquartered in New York, Pager was previously known as techCare, Inc. before rebranding in 2014.

Cardionomic, Inc. is a medical device company focused on developing a catheter-based therapy for acute decompensated heart failure (ADHF). Founded in 2007 and headquartered in New Brighton, Minnesota, Cardionomic's innovative technology utilizes neuromodulation to electrically stimulate cardiac nerves, addressing the underlying issue of reduced cardiac output. The device is inserted into the right pulmonary artery via the internal jugular vein, where it selectively stimulates autonomic nerves to enhance ventricular contractility without impacting heart rate. This approach aims to improve cardiac output, renal blood flow, urine production, and pharmacological tolerance. Additionally, the therapy helps reduce levels of plasma norepinephrine and B-type natriuretic peptide, which are key biomarkers associated with chronic heart failure. By targeting the root cause of ADHF, Cardionomic seeks to enhance patient outcomes and reduce complications in healthcare settings.

ChromaCode Inc., established in 2012 and based in Carlsbad, California, specializes in molecular diagnostics. The company develops innovative testing solutions for infectious diseases, cancer, and non-invasive prenatal testing (NIPT) using technology licensed from Caltech. ChromaCode's core products are software, reagents, and assays that enhance the multiplexing capabilities of quantitative PCR (qPCR) instruments by fivefold. Additionally, they offer molecular assays and software for various applications such as personalized medicine and pharmaceutical research. One of their notable products is the HDPCR Tick-Borne Pathogen Panel, a multiplex PCR test detecting common tick-borne pathogens in a single assay. ChromaCode's technology focuses on improving signal processing from life science instrumentation, enabling cost-effective testing of multiple targets simultaneously while integrating into existing laboratory workflows.

Collective Health is a health benefits platform that integrates various medical, dental, vision, and pharmacy services into a cohesive solution aimed at simplifying healthcare for employees and their families. The company’s cloud-based platform streamlines the administration of health plans through a single portal, offering clear guidance, live concierge support, and digital tools for managing care. By reducing the administrative burden associated with health benefits, Collective Health enhances the member experience and aids organizations in controlling costs while improving health outcomes. Headquartered in San Francisco, California, the company also has offices in Chicago, Illinois, and Lehi, Utah.

Tempus, established in 2015 and based in Chicago, Illinois, is a technology company specializing in precision medicine. It develops a comprehensive library of molecular and clinical data, along with an operating system that makes this information accessible and useful for patients, physicians, and researchers. Tempus offers services such as genomic sequencing, clinical data restructuring, and biological modeling, enabling real-time data-driven decisions for personalized patient care and facilitating the discovery of optimized therapeutic options.

Vesper Medical, Inc. is a medical device company based in Wayne, Pennsylvania, founded in 2016. The company specializes in the development of minimally invasive peripheral vascular products aimed at treating patients with deep venous disease. Its primary offering is the Vesper DUO Venous Stent System, designed specifically for venous stenting. This system features a unique combination of strength and flexibility to address the complex anatomical challenges encountered in the iliac and femoral veins. Vesper Medical is dedicated to creating safe, effective, and user-friendly products that enhance patient care and support healthcare providers in improving patient outcomes in venous treatment.

Strive Health, LLC is a company focused on providing comprehensive solutions for chronic kidney disease. Founded in 2018 and based in Denver, Colorado, Strive Health operates dialysis centers and employs advanced predictive analytics to enhance patient care. The company offers a high-touch, technology-enabled clinical model that supports patients throughout their healthcare journey, from primary care engagement to dialysis treatment. By utilizing comparative and predictive data, Strive Health aims to identify at-risk patients and transform the management of kidney disease, promoting earlier intervention and increasing the adoption of home dialysis. This innovative approach not only improves patient outcomes but also seeks to reduce inpatient utilization, ultimately enhancing the overall experience for individuals dealing with chronic kidney conditions.

Eargo, Inc. is a consumer-focused medical device company specializing in the design and sale of hearing aids for individuals with hearing loss in the United States. Founded in 2010 and headquartered in San Jose, California, Eargo offers innovative, rechargeable hearing aids that can be controlled via smartphone, enhancing user convenience. The company provides online hearing screenings and virtual support, eliminating the need for in-person consultations. By adopting a direct-to-consumer model, Eargo aims to make hearing aids more accessible and reduce the social stigma often associated with them. Its user-centric approach addresses the common challenges of traditional hearing aid adoption, including cost and accessibility, thereby improving the quality of life for those with hearing difficulties.

FabFitFun, Inc. is a subscription-based lifestyle company that specializes in providing curated boxes of health and beauty products to its customers. Founded in 2010 and headquartered in Los Angeles, the company delivers seasonal gift boxes every three months, which include full-size items from both premium and emerging brands across categories such as beauty, fashion, wellness, and fitness. In addition to its subscription service, FabFitFun offers an online platform featuring lifestyle content on various topics, including health, fitness, entertainment, and shopping, aimed particularly at women. The company also engages its audience through a daily email service that provides tips on beauty, wellness, and fashion. FabFitFun operates as a subsidiary of Unilever N.V., fostering a community focused on enabling women to lead healthier and more fulfilling lives.

EarLens is a privately held medical technology company focused on enhancing the hearing experience for individuals with hearing loss. The firm has pioneered the Earlens Contact Hearing Solution, a groundbreaking device that directly activates the natural hearing process. This innovative system utilizes low-frequency radio signals and a small lens placed on the eardrum to vibrate it, allowing for superior sound quality and a broader bandwidth than traditional hearing aids. Unlike conventional devices that amplify sound, the Earlens solution delivers sound directly to the eardrum, thereby minimizing feedback and ensuring clear hearing in various environments. The second generation of this technology received FDA clearance in 2019, marking a significant advancement in the standard of care for hearing performance.

Tempus, established in 2015 and based in Chicago, Illinois, is a technology company specializing in precision medicine. It develops a comprehensive library of molecular and clinical data, along with an operating system that makes this information accessible and useful for patients, physicians, and researchers. Tempus offers services such as genomic sequencing, clinical data restructuring, and biological modeling, enabling real-time data-driven decisions for personalized patient care and facilitating the discovery of optimized therapeutic options.

Everside Health is a direct primary care provider founded in 2010 and based in Denver, Colorado. The company offers a range of services, including biometric screenings, health risk assessments, lifestyle coaching, and acute care, catering to patients across the nation. Everside's healthcare delivery model is data-driven and patient-centric, focusing on convenient on-site, near-site, and virtual care options. By aligning incentives among patients, physicians, and benefit providers, Everside aims to enhance patient engagement and overall health while simultaneously reducing the total cost of care.

Everside Health is a direct primary care provider founded in 2010 and based in Denver, Colorado. The company offers a range of services, including biometric screenings, health risk assessments, lifestyle coaching, and acute care, catering to patients across the nation. Everside's healthcare delivery model is data-driven and patient-centric, focusing on convenient on-site, near-site, and virtual care options. By aligning incentives among patients, physicians, and benefit providers, Everside aims to enhance patient engagement and overall health while simultaneously reducing the total cost of care.

Vesper Medical, Inc. is a medical device company based in Wayne, Pennsylvania, founded in 2016. The company specializes in the development of minimally invasive peripheral vascular products aimed at treating patients with deep venous disease. Its primary offering is the Vesper DUO Venous Stent System, designed specifically for venous stenting. This system features a unique combination of strength and flexibility to address the complex anatomical challenges encountered in the iliac and femoral veins. Vesper Medical is dedicated to creating safe, effective, and user-friendly products that enhance patient care and support healthcare providers in improving patient outcomes in venous treatment.

Tempus, established in 2015 and based in Chicago, Illinois, is a technology company specializing in precision medicine. It develops a comprehensive library of molecular and clinical data, along with an operating system that makes this information accessible and useful for patients, physicians, and researchers. Tempus offers services such as genomic sequencing, clinical data restructuring, and biological modeling, enabling real-time data-driven decisions for personalized patient care and facilitating the discovery of optimized therapeutic options.

Collective Health is a health benefits platform that integrates various medical, dental, vision, and pharmacy services into a cohesive solution aimed at simplifying healthcare for employees and their families. The company’s cloud-based platform streamlines the administration of health plans through a single portal, offering clear guidance, live concierge support, and digital tools for managing care. By reducing the administrative burden associated with health benefits, Collective Health enhances the member experience and aids organizations in controlling costs while improving health outcomes. Headquartered in San Francisco, California, the company also has offices in Chicago, Illinois, and Lehi, Utah.

Fire1 is a Dublin-based company dedicated to developing innovative therapeutic devices aimed at enhancing the quality of life for heart failure patients. The company has created a remote monitoring system that delivers real-time patient data and insights to healthcare providers. This technology facilitates the early detection of complications associated with heart failure, allowing for proactive interventions and ultimately leading to improved patient outcomes. Through its focus on remote monitoring, Fire1 seeks to transform the management of heart failure and support better health management for patients.

Pager, Inc. is a company that operates an on-demand service platform designed to connect patients with healthcare services in various settings including homes, offices, and hotels. The company offers a mobile application that facilitates access to urgent care for a range of conditions such as infections, respiratory issues, and allergies. In addition to its core services, Pager provides nurse chat, teleconsultation, screening, vaccination, and prescription delivery. The company's mission focuses on improving healthcare accessibility, lowering costs, and simplifying care navigation through a flexible platform that integrates artificial intelligence and service teams. Amidst its extensive offerings, Pager supports over 15 million individuals across the United States and Latin America, enabling coordinated care that enhances patient engagement and decision-making. Incorporated in 2013 and headquartered in New York, Pager was previously known as techCare, Inc. before rebranding in 2014.

Eargo, Inc. is a consumer-focused medical device company specializing in the design and sale of hearing aids for individuals with hearing loss in the United States. Founded in 2010 and headquartered in San Jose, California, Eargo offers innovative, rechargeable hearing aids that can be controlled via smartphone, enhancing user convenience. The company provides online hearing screenings and virtual support, eliminating the need for in-person consultations. By adopting a direct-to-consumer model, Eargo aims to make hearing aids more accessible and reduce the social stigma often associated with them. Its user-centric approach addresses the common challenges of traditional hearing aid adoption, including cost and accessibility, thereby improving the quality of life for those with hearing difficulties.

Tempus, established in 2015 and based in Chicago, Illinois, is a technology company specializing in precision medicine. It develops a comprehensive library of molecular and clinical data, along with an operating system that makes this information accessible and useful for patients, physicians, and researchers. Tempus offers services such as genomic sequencing, clinical data restructuring, and biological modeling, enabling real-time data-driven decisions for personalized patient care and facilitating the discovery of optimized therapeutic options.

Nightstar Therapeutics is a clinical-stage gene therapy company based in London, United Kingdom, specializing in the development of innovative one-time treatments for rare inherited retinal diseases. The company is advancing several product candidates, including its lead candidate NSR-REP1, which is in phase 3 clinical development for choroideremia. Additionally, Nightstar is working on NSR-RPGR, currently in phase 2/3 trials for X-linked retinitis pigmentosa, as well as NSR-BEST1. The company is also developing NSR-ABCA4, which is in preclinical development for Stargardt disease. Founded in 2017, Nightstar Therapeutics aims to address significant unmet medical needs in the field of retinal disorders.

EarLens is a privately held medical technology company focused on enhancing the hearing experience for individuals with hearing loss. The firm has pioneered the Earlens Contact Hearing Solution, a groundbreaking device that directly activates the natural hearing process. This innovative system utilizes low-frequency radio signals and a small lens placed on the eardrum to vibrate it, allowing for superior sound quality and a broader bandwidth than traditional hearing aids. Unlike conventional devices that amplify sound, the Earlens solution delivers sound directly to the eardrum, thereby minimizing feedback and ensuring clear hearing in various environments. The second generation of this technology received FDA clearance in 2019, marking a significant advancement in the standard of care for hearing performance.

ChromaCode Inc., established in 2012 and based in Carlsbad, California, specializes in molecular diagnostics. The company develops innovative testing solutions for infectious diseases, cancer, and non-invasive prenatal testing (NIPT) using technology licensed from Caltech. ChromaCode's core products are software, reagents, and assays that enhance the multiplexing capabilities of quantitative PCR (qPCR) instruments by fivefold. Additionally, they offer molecular assays and software for various applications such as personalized medicine and pharmaceutical research. One of their notable products is the HDPCR Tick-Borne Pathogen Panel, a multiplex PCR test detecting common tick-borne pathogens in a single assay. ChromaCode's technology focuses on improving signal processing from life science instrumentation, enabling cost-effective testing of multiple targets simultaneously while integrating into existing laboratory workflows.

Vertiflex Inc., established in 2005 and headquartered in Carlsbad, California, is a medical device company specializing in minimally invasive spinal surgery technologies. The company's primary product is the Superion Interspinous Spacer, a titanium implant designed to treat moderate lumbar spinal stenosis by fitting between the spinous processes in the lumbar spine. This motion-preserving solution offers an indirect decompression system, providing an alternative treatment option for patients with lumbar stenosis who may not require traditional spine surgery. As of June 11, 2019, Vertiflex Inc. operates as a subsidiary of Boston Scientific Corporation.

Trillium Therapeutics Inc. is a clinical-stage immuno-oncology company based in Mississauga, Canada, that specializes in developing therapies for cancer treatment. The company focuses on harnessing the immune system to combat malignancies through innovative protein therapeutics. Its lead program, TTI-621, is a SIRPaFc fusion protein currently undergoing Phase I clinical trials for advanced relapsed or refractory hematologic malignancies, solid tumors, and mycosis fungoides. Additionally, Trillium is advancing TTI-622, another SIRPaFc protein in Phase I trials, while also exploring TTI-10001, a small molecule stimulator of interferon genes agonist in the discovery phase. Originally founded in 2004, the company has undergone several name changes, reflecting its evolving focus within the biopharmaceutical sector.

Pager, Inc. is a company that operates an on-demand service platform designed to connect patients with healthcare services in various settings including homes, offices, and hotels. The company offers a mobile application that facilitates access to urgent care for a range of conditions such as infections, respiratory issues, and allergies. In addition to its core services, Pager provides nurse chat, teleconsultation, screening, vaccination, and prescription delivery. The company's mission focuses on improving healthcare accessibility, lowering costs, and simplifying care navigation through a flexible platform that integrates artificial intelligence and service teams. Amidst its extensive offerings, Pager supports over 15 million individuals across the United States and Latin America, enabling coordinated care that enhances patient engagement and decision-making. Incorporated in 2013 and headquartered in New York, Pager was previously known as techCare, Inc. before rebranding in 2014.

Cleave Therapeutics, Inc. is a biopharmaceutical company based in San Francisco, California, founded in 2010. The company focuses on developing novel small-molecule drugs that target valosin-containing protein and other protein-degradation pathways critical for the survival of cancer cells. By creating enzyme inhibitors designed to disrupt these pathways, Cleave Therapeutics aims to address both oncological and neurodegenerative diseases. Through its innovative approach to drug discovery, the company seeks to provide effective therapeutic solutions that enhance patient outcomes in the fight against cancer.

Docent Health is a company based in Cambridge, Massachusetts, that specializes in developing software and mobile applications aimed at enhancing patient care and engagement for health systems. Its enterprise consumer engagement platform integrates digital and human interactions to provide personalized support for patients, guiding them according to their specific needs and preferences. By utilizing intelligent, real-time text messaging, Docent Health focuses on fostering lasting patient relationships and improving customer experiences. The company's approach combines insights from various industries, including retail and hospitality, to deliver customer-centric care that enhances patient satisfaction, increases customer lifetime value, and helps health systems grow their market share.

EarLens is a privately held medical technology company focused on enhancing the hearing experience for individuals with hearing loss. The firm has pioneered the Earlens Contact Hearing Solution, a groundbreaking device that directly activates the natural hearing process. This innovative system utilizes low-frequency radio signals and a small lens placed on the eardrum to vibrate it, allowing for superior sound quality and a broader bandwidth than traditional hearing aids. Unlike conventional devices that amplify sound, the Earlens solution delivers sound directly to the eardrum, thereby minimizing feedback and ensuring clear hearing in various environments. The second generation of this technology received FDA clearance in 2019, marking a significant advancement in the standard of care for hearing performance.

Fire1 is a Dublin-based company dedicated to developing innovative therapeutic devices aimed at enhancing the quality of life for heart failure patients. The company has created a remote monitoring system that delivers real-time patient data and insights to healthcare providers. This technology facilitates the early detection of complications associated with heart failure, allowing for proactive interventions and ultimately leading to improved patient outcomes. Through its focus on remote monitoring, Fire1 seeks to transform the management of heart failure and support better health management for patients.

Docent Health is a company based in Cambridge, Massachusetts, that specializes in developing software and mobile applications aimed at enhancing patient care and engagement for health systems. Its enterprise consumer engagement platform integrates digital and human interactions to provide personalized support for patients, guiding them according to their specific needs and preferences. By utilizing intelligent, real-time text messaging, Docent Health focuses on fostering lasting patient relationships and improving customer experiences. The company's approach combines insights from various industries, including retail and hospitality, to deliver customer-centric care that enhances patient satisfaction, increases customer lifetime value, and helps health systems grow their market share.

DOTS Technology Corp, founded in 2013 and located in Natick, Massachusetts, operates a diagnostic platform designed to assist consumers with food allergies. The company is focused on developing a food allergen detection system that allows users to test food on the spot, providing immediate information to enhance decision-making and improve the overall quality of life for individuals affected by food allergies. By advancing point-of-care detection technology, DOTS aims to address the needs of millions of consumers and has applications in both consumer and industrial sectors.

Eargo, Inc. is a consumer-focused medical device company specializing in the design and sale of hearing aids for individuals with hearing loss in the United States. Founded in 2010 and headquartered in San Jose, California, Eargo offers innovative, rechargeable hearing aids that can be controlled via smartphone, enhancing user convenience. The company provides online hearing screenings and virtual support, eliminating the need for in-person consultations. By adopting a direct-to-consumer model, Eargo aims to make hearing aids more accessible and reduce the social stigma often associated with them. Its user-centric approach addresses the common challenges of traditional hearing aid adoption, including cost and accessibility, thereby improving the quality of life for those with hearing difficulties.

Nightstar Therapeutics is a clinical-stage gene therapy company based in London, United Kingdom, specializing in the development of innovative one-time treatments for rare inherited retinal diseases. The company is advancing several product candidates, including its lead candidate NSR-REP1, which is in phase 3 clinical development for choroideremia. Additionally, Nightstar is working on NSR-RPGR, currently in phase 2/3 trials for X-linked retinitis pigmentosa, as well as NSR-BEST1. The company is also developing NSR-ABCA4, which is in preclinical development for Stargardt disease. Founded in 2017, Nightstar Therapeutics aims to address significant unmet medical needs in the field of retinal disorders.

Cardionomic, Inc. is a medical device company focused on developing a catheter-based therapy for acute decompensated heart failure (ADHF). Founded in 2007 and headquartered in New Brighton, Minnesota, Cardionomic's innovative technology utilizes neuromodulation to electrically stimulate cardiac nerves, addressing the underlying issue of reduced cardiac output. The device is inserted into the right pulmonary artery via the internal jugular vein, where it selectively stimulates autonomic nerves to enhance ventricular contractility without impacting heart rate. This approach aims to improve cardiac output, renal blood flow, urine production, and pharmacological tolerance. Additionally, the therapy helps reduce levels of plasma norepinephrine and B-type natriuretic peptide, which are key biomarkers associated with chronic heart failure. By targeting the root cause of ADHF, Cardionomic seeks to enhance patient outcomes and reduce complications in healthcare settings.

Collective Health is a health benefits platform that integrates various medical, dental, vision, and pharmacy services into a cohesive solution aimed at simplifying healthcare for employees and their families. The company’s cloud-based platform streamlines the administration of health plans through a single portal, offering clear guidance, live concierge support, and digital tools for managing care. By reducing the administrative burden associated with health benefits, Collective Health enhances the member experience and aids organizations in controlling costs while improving health outcomes. Headquartered in San Francisco, California, the company also has offices in Chicago, Illinois, and Lehi, Utah.

FabFitFun, Inc. is a subscription-based lifestyle company that specializes in providing curated boxes of health and beauty products to its customers. Founded in 2010 and headquartered in Los Angeles, the company delivers seasonal gift boxes every three months, which include full-size items from both premium and emerging brands across categories such as beauty, fashion, wellness, and fitness. In addition to its subscription service, FabFitFun offers an online platform featuring lifestyle content on various topics, including health, fitness, entertainment, and shopping, aimed particularly at women. The company also engages its audience through a daily email service that provides tips on beauty, wellness, and fashion. FabFitFun operates as a subsidiary of Unilever N.V., fostering a community focused on enabling women to lead healthier and more fulfilling lives.

Pager, Inc. is a company that operates an on-demand service platform designed to connect patients with healthcare services in various settings including homes, offices, and hotels. The company offers a mobile application that facilitates access to urgent care for a range of conditions such as infections, respiratory issues, and allergies. In addition to its core services, Pager provides nurse chat, teleconsultation, screening, vaccination, and prescription delivery. The company's mission focuses on improving healthcare accessibility, lowering costs, and simplifying care navigation through a flexible platform that integrates artificial intelligence and service teams. Amidst its extensive offerings, Pager supports over 15 million individuals across the United States and Latin America, enabling coordinated care that enhances patient engagement and decision-making. Incorporated in 2013 and headquartered in New York, Pager was previously known as techCare, Inc. before rebranding in 2014.

Collective Health is a health benefits platform that integrates various medical, dental, vision, and pharmacy services into a cohesive solution aimed at simplifying healthcare for employees and their families. The company’s cloud-based platform streamlines the administration of health plans through a single portal, offering clear guidance, live concierge support, and digital tools for managing care. By reducing the administrative burden associated with health benefits, Collective Health enhances the member experience and aids organizations in controlling costs while improving health outcomes. Headquartered in San Francisco, California, the company also has offices in Chicago, Illinois, and Lehi, Utah.

Collective Health is a health benefits platform that integrates various medical, dental, vision, and pharmacy services into a cohesive solution aimed at simplifying healthcare for employees and their families. The company’s cloud-based platform streamlines the administration of health plans through a single portal, offering clear guidance, live concierge support, and digital tools for managing care. By reducing the administrative burden associated with health benefits, Collective Health enhances the member experience and aids organizations in controlling costs while improving health outcomes. Headquartered in San Francisco, California, the company also has offices in Chicago, Illinois, and Lehi, Utah.

U.S. Renal Care, Inc. is a healthcare service provider specializing in dialysis for patients with chronic kidney failure. Established in 2000 and headquartered in Plano, Texas, the company operates a network of 335 dialysis facilities across 32 states and the Territory of Guam, serving over 25,000 patients. U.S. Renal Care offers a range of services, including in-center hemodialysis, at-home hemodialysis, and peritoneal dialysis, specifically catering to those with end-stage renal disease. In addition to its outpatient and home dialysis programs, the company collaborates with local community hospitals to manage acute setting dialysis programs. U.S. Renal Care also provides support for families, caregivers, and physicians involved in patient care, operating with a business model that includes partnerships with local nephrologists.

Dermira, Inc. is a biopharmaceutical company that specializes in developing and commercializing therapies for dermatologic diseases, primarily targeting the U.S. market. Founded in 2010 and headquartered in Menlo Park, California, Dermira offers QBREXZA, a topical treatment for primary axillary hyperhidrosis in patients aged nine and older. The company is also advancing its pipeline with lebrikizumab, a monoclonal antibody currently in Phase IIb trials for moderate-to-severe atopic dermatitis, alongside several other early-stage research initiatives in dermatology. Dermira has established strategic partnerships for the development and commercialization of its products, including agreements with Maruho Co., Ltd., F. Hoffmann-La Roche Ltd, Genentech, Inc., and UCB Pharma S.A. Notably, Dermira was previously known as Skintelligence, Inc. before rebranding in September 2011. As of early 2020, Dermira operates as a subsidiary of Eli Lilly and Company.

D2L Corporation is a learning innovation company founded in 1999 and headquartered in Kitchener, Canada, with additional locations in Toronto, Winnipeg, Maryland, Australia, and the United Kingdom. The company specializes in providing cloud-based learning solutions through its platform, Brightspace, which serves a diverse range of clients, including higher education institutions, K-12 schools, healthcare organizations, government agencies, and enterprise sectors. Brightspace combines usability, integrated analytics, and accessibility to enhance the learning experience, offering tools such as course recommendations, adaptive learning, online grading, and mobile applications that facilitate student engagement. D2L aims to inspire lifelong learning by delivering high-quality educational experiences to over 700 clients and more than 8 million learners globally.

EarLens is a privately held medical technology company focused on enhancing the hearing experience for individuals with hearing loss. The firm has pioneered the Earlens Contact Hearing Solution, a groundbreaking device that directly activates the natural hearing process. This innovative system utilizes low-frequency radio signals and a small lens placed on the eardrum to vibrate it, allowing for superior sound quality and a broader bandwidth than traditional hearing aids. Unlike conventional devices that amplify sound, the Earlens solution delivers sound directly to the eardrum, thereby minimizing feedback and ensuring clear hearing in various environments. The second generation of this technology received FDA clearance in 2019, marking a significant advancement in the standard of care for hearing performance.

Fire1 is a Dublin-based company dedicated to developing innovative therapeutic devices aimed at enhancing the quality of life for heart failure patients. The company has created a remote monitoring system that delivers real-time patient data and insights to healthcare providers. This technology facilitates the early detection of complications associated with heart failure, allowing for proactive interventions and ultimately leading to improved patient outcomes. Through its focus on remote monitoring, Fire1 seeks to transform the management of heart failure and support better health management for patients.

Collective Health is a health benefits platform that integrates various medical, dental, vision, and pharmacy services into a cohesive solution aimed at simplifying healthcare for employees and their families. The company’s cloud-based platform streamlines the administration of health plans through a single portal, offering clear guidance, live concierge support, and digital tools for managing care. By reducing the administrative burden associated with health benefits, Collective Health enhances the member experience and aids organizations in controlling costs while improving health outcomes. Headquartered in San Francisco, California, the company also has offices in Chicago, Illinois, and Lehi, Utah.

Dermira, Inc. is a biopharmaceutical company that specializes in developing and commercializing therapies for dermatologic diseases, primarily targeting the U.S. market. Founded in 2010 and headquartered in Menlo Park, California, Dermira offers QBREXZA, a topical treatment for primary axillary hyperhidrosis in patients aged nine and older. The company is also advancing its pipeline with lebrikizumab, a monoclonal antibody currently in Phase IIb trials for moderate-to-severe atopic dermatitis, alongside several other early-stage research initiatives in dermatology. Dermira has established strategic partnerships for the development and commercialization of its products, including agreements with Maruho Co., Ltd., F. Hoffmann-La Roche Ltd, Genentech, Inc., and UCB Pharma S.A. Notably, Dermira was previously known as Skintelligence, Inc. before rebranding in September 2011. As of early 2020, Dermira operates as a subsidiary of Eli Lilly and Company.

Cleave Therapeutics, Inc. is a biopharmaceutical company based in San Francisco, California, founded in 2010. The company focuses on developing novel small-molecule drugs that target valosin-containing protein and other protein-degradation pathways critical for the survival of cancer cells. By creating enzyme inhibitors designed to disrupt these pathways, Cleave Therapeutics aims to address both oncological and neurodegenerative diseases. Through its innovative approach to drug discovery, the company seeks to provide effective therapeutic solutions that enhance patient outcomes in the fight against cancer.

D2L Corporation is a learning innovation company founded in 1999 and headquartered in Kitchener, Canada, with additional locations in Toronto, Winnipeg, Maryland, Australia, and the United Kingdom. The company specializes in providing cloud-based learning solutions through its platform, Brightspace, which serves a diverse range of clients, including higher education institutions, K-12 schools, healthcare organizations, government agencies, and enterprise sectors. Brightspace combines usability, integrated analytics, and accessibility to enhance the learning experience, offering tools such as course recommendations, adaptive learning, online grading, and mobile applications that facilitate student engagement. D2L aims to inspire lifelong learning by delivering high-quality educational experiences to over 700 clients and more than 8 million learners globally.

Nova Specialty Hospitals (formerly Nova Specialty Surgery) is a fully equipped medical facility located conveniently in your neighborhood. It brings cutting edge medical technology and internationally trained physicians under one roof to give patients easy access to quality, affordable healthcare. Nova's medical services are based on the out-patient care model that enables quicker diagnosis and reduces patients' recovery time. This healthcare delivery system optimizes our staff's efficiency while reducing operational costs, thereby providing incomparable value and convenience to our patients.

Carticept Medical specializes in developing and distributing medical products aimed at improving the lives of individuals with osteoarthritis or cartilage damage. Their primary offering is a cartilage implant product designed to enhance joint function and alleviate symptoms associated with these conditions. Additionally, they distribute Sonosite ultrasound products, which are used for diagnostic imaging purposes within the orthopedic field.

Roka Bioscience specializes in the development of rapid and accurate molecular assays and instrument systems aimed at the food safety industry. The company's latest innovation, the Atlas System, introduces advanced molecular rapid pathogen testing, which enhances laboratory efficiency through automation and user-friendly design. By focusing on innovative testing solutions, Roka Bioscience aims to assist food manufacturers in minimizing risks, safeguarding their brands, and addressing the growing demands for testing in the sector.

Dermira, Inc. is a biopharmaceutical company that specializes in developing and commercializing therapies for dermatologic diseases, primarily targeting the U.S. market. Founded in 2010 and headquartered in Menlo Park, California, Dermira offers QBREXZA, a topical treatment for primary axillary hyperhidrosis in patients aged nine and older. The company is also advancing its pipeline with lebrikizumab, a monoclonal antibody currently in Phase IIb trials for moderate-to-severe atopic dermatitis, alongside several other early-stage research initiatives in dermatology. Dermira has established strategic partnerships for the development and commercialization of its products, including agreements with Maruho Co., Ltd., F. Hoffmann-La Roche Ltd, Genentech, Inc., and UCB Pharma S.A. Notably, Dermira was previously known as Skintelligence, Inc. before rebranding in September 2011. As of early 2020, Dermira operates as a subsidiary of Eli Lilly and Company.

Roka Bioscience specializes in the development of rapid and accurate molecular assays and instrument systems aimed at the food safety industry. The company's latest innovation, the Atlas System, introduces advanced molecular rapid pathogen testing, which enhances laboratory efficiency through automation and user-friendly design. By focusing on innovative testing solutions, Roka Bioscience aims to assist food manufacturers in minimizing risks, safeguarding their brands, and addressing the growing demands for testing in the sector.

Vertiflex Inc., established in 2005 and headquartered in Carlsbad, California, is a medical device company specializing in minimally invasive spinal surgery technologies. The company's primary product is the Superion Interspinous Spacer, a titanium implant designed to treat moderate lumbar spinal stenosis by fitting between the spinous processes in the lumbar spine. This motion-preserving solution offers an indirect decompression system, providing an alternative treatment option for patients with lumbar stenosis who may not require traditional spine surgery. As of June 11, 2019, Vertiflex Inc. operates as a subsidiary of Boston Scientific Corporation.

DSI Renal is a prominent provider of dialysis services in the United States, catering to patients with chronic kidney failure. The company operates healthcare centers focused on delivering comprehensive dialysis care, patient support, and assistance for individuals traveling with dialysis needs. DSI Renal aims to enhance its presence through strategic acquisitions, the development of new clinics, and organic growth initiatives, ensuring that it meets the evolving needs of patients diagnosed with kidney disease.

NephroPlus is a network of dialysis centers focused on delivering quality dialysis services at affordable prices. The company employs standardized protocols, continuous training, and innovation to ensure optimal care for patients. Its facilities provide a range of treatments, including dialysis, kidney stone management, and arteriovenous fistula procedures, addressing various renal and urological disorders. Through its specialized approach, NephroPlus aims to enhance patient recovery and overall health outcomes.

Predictive Biosciences, Inc. is a molecular diagnostics company focused on developing diagnostic products aimed at enhancing cancer management. Founded in 2006 and headquartered in Lexington, Massachusetts, the company specializes in proteomics and oncology, particularly in the area of tumor biomarkers. Predictive Biosciences offers a range of assays that detect urinary biomarkers, which are indicative of the physiological changes associated with cancer development and progression. Among its key products are the Triage Monitoring Assay, which enables physicians to postpone invasive diagnostic procedures, the Interval Monitoring Assay for cancer surveillance between follow-up appointments, and the Stratification Assay to assist physicians in managing patient care decisions.

Carticept Medical specializes in developing and distributing medical products aimed at improving the lives of individuals with osteoarthritis or cartilage damage. Their primary offering is a cartilage implant product designed to enhance joint function and alleviate symptoms associated with these conditions. Additionally, they distribute Sonosite ultrasound products, which are used for diagnostic imaging purposes within the orthopedic field.

Rock Health, established in 2011 and headquartered in San Francisco, is a venture capital firm specializing in early-stage investments in digital health. It focuses on supporting entrepreneurs working at the intersection of healthcare and technology, with a particular interest in industrial strength applications for mobile, web, and digital healthcare. The firm invests in companies developing products such as activity-tracking devices, data-analytic tools for reducing healthcare expenses, telemedicine apps, doctor workflow improvement tools, life-science research analytics, and technologies designed to produce clinical outcomes. Rock Health typically invests between $0.1 to $0.25 million per company.

CITIC Pharmaceutical Co., Ltd. (中信医药) is a pharmaceutical service provider that supplies medicine and related consumables to hospitals. It is a large pharmaceutical operation enterprise integrating medicines supply to hospitals, cross-regional commercial distribution, vaccine sale, medical instruments and consumables sale, and medicine retailing service. In recent years, it has become a pharmaceutical service provider in the supply chain with multiple customized integration service. CITIC Pharmaceutical, which is a subsidiary of CITIC Group, was transformed to a joint venture in 2007. It is invested by China Health System whose holding company is Bioveda China fund and CITIC Investment Holdings Ltd.

Clovis Oncology, Inc. is a biopharmaceutical company dedicated to acquiring, developing, and commercializing innovative cancer treatments in the United States, Europe, and other international markets. The company focuses on precision medicine, targeting specific cancer subsets to ensure that therapeutics are directed to patients who are most likely to benefit. Clovis Oncology's primary product is Rubraca, an oral small molecule inhibitor of poly ADP-ribose polymerase, approved for the treatment of recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer. Additionally, the company is developing lucitanib, an oral inhibitor targeting multiple tyrosine kinase receptors involved in cancer progression. Clovis distributes its products through specialty distributors and pharmacy providers, and it engages in various collaborations and licensing agreements with prominent pharmaceutical companies such as Pfizer, AstraZeneca, and Bristol-Myers Squibb. Founded in 2009 and headquartered in Boulder, Colorado, Clovis Oncology is committed to advancing cancer care through targeted therapeutic approaches.

Predictive Biosciences, Inc. is a molecular diagnostics company focused on developing diagnostic products aimed at enhancing cancer management. Founded in 2006 and headquartered in Lexington, Massachusetts, the company specializes in proteomics and oncology, particularly in the area of tumor biomarkers. Predictive Biosciences offers a range of assays that detect urinary biomarkers, which are indicative of the physiological changes associated with cancer development and progression. Among its key products are the Triage Monitoring Assay, which enables physicians to postpone invasive diagnostic procedures, the Interval Monitoring Assay for cancer surveillance between follow-up appointments, and the Stratification Assay to assist physicians in managing patient care decisions.

Vertiflex Inc., established in 2005 and headquartered in Carlsbad, California, is a medical device company specializing in minimally invasive spinal surgery technologies. The company's primary product is the Superion Interspinous Spacer, a titanium implant designed to treat moderate lumbar spinal stenosis by fitting between the spinous processes in the lumbar spine. This motion-preserving solution offers an indirect decompression system, providing an alternative treatment option for patients with lumbar stenosis who may not require traditional spine surgery. As of June 11, 2019, Vertiflex Inc. operates as a subsidiary of Boston Scientific Corporation.

CITIC Pharmaceutical Co., Ltd. (中信医药) is a pharmaceutical service provider that supplies medicine and related consumables to hospitals. It is a large pharmaceutical operation enterprise integrating medicines supply to hospitals, cross-regional commercial distribution, vaccine sale, medical instruments and consumables sale, and medicine retailing service. In recent years, it has become a pharmaceutical service provider in the supply chain with multiple customized integration service. CITIC Pharmaceutical, which is a subsidiary of CITIC Group, was transformed to a joint venture in 2007. It is invested by China Health System whose holding company is Bioveda China fund and CITIC Investment Holdings Ltd.

ForHealth Technologies is a company dedicated to developing automation technology solutions specifically for the intravenous drug preparation process. Founded in 1998 and headquartered in Daytona Beach, Florida, the company has a focus on enhancing the efficiency and safety of drug preparation in healthcare settings. In March 2009, ForHealth Technologies was acquired by Baxa Corporation, further expanding its reach and capabilities within the medical technology sector.

Bariatric Partners is a Charlotte, North Carolina-based company that focuses on developing a network of surgical facilities specifically tailored for individuals suffering from severe obesity. The company operates specialty outpatient facilities to address the surgical needs of obese patients, ensuring a comprehensive approach to their care. Bariatric Partners collaborates closely with physician partners, who contribute to the design and layout of the facilities, as well as the selection of medical equipment and the recruitment of essential staff. In addition to surgical services, the company plays a significant role in creating and implementing patient support services, enhancing the overall patient experience and outcomes.

Aradigm Corporation was a specialty pharmaceutical company based in Hayward, California, focused on the development and commercialization of inhaled drug formulations for the treatment and prevention of severe respiratory diseases. Founded in 1991, the company primarily worked on proprietary formulations of ciprofloxacin, targeting conditions such as non-cystic fibrosis bronchiectasis and cystic fibrosis, as well as treating infections related to inhaled bioterrorism threats. Its product candidates included Linhaliq and Lipoquin, designed for inhalation delivery. In addition to respiratory diseases, Aradigm explored treatments for smoking cessation and had entered into collaboration agreements for its research and development efforts. However, the company filed for Chapter 11 bankruptcy and ceased operations on June 29, 2020.

MedSpecialists, Inc. is an e-Health company dedicated to addressing the clinical needs of medical specialists, including neurosurgeons, radiation oncologists, cardiologists, gastroenterologists, and orthopedists. Recognizing that these highly mobile physicians often rely on various manual and computerized systems for medical decision-making, MedSpecialists aims to reduce the workflow inefficiencies caused by isolated systems and differing media formats. The company has developed a suite of specialty-specific clinical portals that leverage Internet technologies to provide specialists with streamlined access to essential information and clinical applications. This innovative approach enables medical specialists to deliver high-quality care in a more cost-effective and time-efficient manner. Founded by a group of physicians and healthcare management professionals, MedSpecialists is committed to improving patient care and enhancing the operational efficiency of specialty medicine practices.

Appriva Medical is engaged in the design and manufacture of medical equipment for preventing cardioembolic stroke in patients with atrial fibrillation.

WebMD is a prominent provider of health information and services aimed at both consumers and healthcare professionals. The company offers a wide range of resources, including online health-focused publications and decision-support applications, that empower users to manage their health actively. WebMD delivers objective healthcare and lifestyle information through various platforms, enabling individuals to access critical data about conditions such as HIV, diabetes, depression, and cancer. It also serves healthcare professionals by providing access to clinical reference sources, the latest treatment options, and opportunities for continuing medical education. Additionally, WebMD collaborates with employers and health plans to offer personalized health information and decision support tools for employees and plan members, fostering informed choices regarding benefits, providers, and treatment options.

Diatide is engaged in the imaging marketplace, engaged in peptide engineering, molecular biology, and radiolabeling chemistry to develop disease-specific diagnostic and therapeutic agents.

Life Technologies Corporation is a biotechnology tools company formed in November 2008 from the merger of Invitrogen Corporation and Applied Biosystems, Inc. The company operates under these well-known brands, providing a comprehensive range of systems, consumables, and services that facilitate scientific research and development. Invitrogen specializes in reagents and consumables applicable across various platforms, while Applied Biosystems offers integrated solutions in critical areas such as polymerase chain reaction (PCR), genetic sequencing, and mass spectrometry. Life Technologies' diverse product portfolio includes technologies for capillary electrophoresis-based sequencing, sample preparation, cell culture, RNA interference analysis, functional genomics, proteomics, and cell biology, in addition to applications in clinical diagnostics and water testing analysis. Through its offerings, Life Technologies supports researchers in accelerating their scientific endeavors.