National Science Foundation

The National Science Foundation (NSF) is an independent federal agency established in 1950 and based in Alexandria, Virginia. It is dedicated to supporting research and education in science and engineering across a wide range of disciplines. The NSF provides significant non-dilutive funding, up to $1.5 million, to startups and small businesses through its America's Seed Fund initiative, which is part of the Small Business Innovation Research (SBIR) program mandated by Congress. With an operating budget of approximately $7.8 billion, the NSF is committed to advancing fundamental research and education, thus fostering innovation and technological development in the United States.

James Donlon

Program Director

Debasis Majumdar

Program Director

Graciela Narcho

Staff Associate

Sethuraman Panchanathan

Director

Past deals in Simulation

ReSuture

Grant in 2023
ReSuture is a company that specializes in creating high-fidelity physical simulations for surgical training, particularly focusing on open vascular procedures. Established in 2019, its primary goal is to enhance patient outcomes and minimize surgical complications by providing a superior training experience for aspiring surgeons. The company develops advanced surgical instruments that address challenges in medical simulation, allowing users to practice vascular surgical skills in a controlled environment. These instruments replicate the mechanical properties of human vascular tissue, enabling realistic simulations that improve psychomotor skills and reduce training time for medical practitioners.

CyberSpara

Grant in 2022
CyberSpara offers a simulation-based educational model that uses gamification principles to educate internet users on common privacy and security vulnerabilities encountered on social media platforms. They offer Digital-PASS to empower individuals to mitigate security threats from the Internet.

QSimulate

Grant in 2022
QSimulate is a Boston-based company that develops cloud-based quantitative simulation tools aimed at addressing complex challenges in the chemical and pharmaceutical industries. By harnessing the principles of quantum mechanics, QSimulate’s platform facilitates quantum molecular simulations, allowing clients to tackle industrial-scale problems more effectively. The tools offered by the company automate workflows, relieving computational scientists of routine tasks and thereby increasing productivity. This innovation enables organizations to accelerate their research and development processes, ultimately enhancing their capacity to innovate and solve critical issues in their fields.

Resolved Analytics

Grant in 2022
Resolved Analytics is a professional engineering company that focuses on partnering with clients to enhance their development processes. The company aims to reduce development cycle times and costs while improving product design and troubleshooting existing designs. It specializes in computational engineering, offering services such as fluid-structure interactions, electrodynamics, magnetics, discrete element modeling, and computational fluid dynamics. By leveraging advanced simulation techniques, Resolved Analytics provides state-of-the-art visualizations and results that help businesses achieve their engineering goals and desired outcomes effectively.

Intelligent Medicine

Grant in 2022
Intelligent Medicine specializes in software and simulation services focused on enhancing safety in medical environments through innovative technologies. The company has developed a simulation platform that enables architects and facility stakeholders to evaluate and optimize building designs and operational protocols. By testing various designs and protocols, the platform helps to identify areas for improvement, thereby reducing the likelihood of infectious disease transmission and alleviating user congestion. This capability allows for a rapid feedback loop, supporting the planning and implementation of effective safety policies and design strategies to improve overall outcomes in healthcare settings.

Omega Hydrodynamics Research

Grant in 2022
Omega Hydrodynamics Research is developing solutions to challenging fluid-structure interaction problems with fast cloud-based CFD software. Their OMEGA-CFD is a novel computational fluid dynamics software for simulating transient fluid-structure interaction problems. Their OMEGA-SW is a comprehensive numerical model for simulating wave-ship-bathymetry interaction in shallow water.

Innovision

Grant in 2022
Innovision provides a technology platform that includes human modeling and simulation, dynamic avatars with complete articulated anatomy, and human activity replication tools, enabling scientists and engineers to research and technically serve in the area of digital human modeling.

HC Simulation

Grant in 2021
HC Simulation specializes in products that use the HumMod engine to provide a high-quality simulation of human physiology. The company was founded in 2011 and is headquartered in Canton, Mississippi.

Simpact

Grant in 2021
Simpact develops analytics and forecasting software to help businesses make data-driven decisions. The company's headquarters are in Boston, Massachusetts.

DeepSim

Grant in 2021
DeepSim specializes in electronic design automation (EDA) technology that enhances the efficiency of chip design and verification processes. The company's innovative solutions facilitate non-electronic circuit simulations, allowing chip designers to detect and address voltage, current, and stress anomalies within their designs. By streamlining these critical aspects of chip development, DeepSim aims to improve the overall reliability and performance of electronic circuits.

VeriSIM Life

Grant in 2021
VeriSIM Life, Inc. is a biotechnology company based in San Francisco, California, that specializes in developing disease-specific biosimulation models to enhance drug development processes. Founded in 2017, the company utilizes its proprietary BIOiSIM platform to predict the clinical outcomes of new drugs prior to clinical trials, thereby replacing traditional animal testing methods. By employing artificial intelligence, VeriSIM Life aims to improve the accuracy and efficiency of drug development, ultimately contributing to personalized healthcare solutions. Their offerings are tailored to meet the needs of both pre-clinical and clinical programs, focusing on small molecules, large molecules, and viruses to facilitate better treatment options and increase human life expectancy.

ReSuture

Grant in 2021
ReSuture is a company that specializes in creating high-fidelity physical simulations for surgical training, particularly focusing on open vascular procedures. Established in 2019, its primary goal is to enhance patient outcomes and minimize surgical complications by providing a superior training experience for aspiring surgeons. The company develops advanced surgical instruments that address challenges in medical simulation, allowing users to practice vascular surgical skills in a controlled environment. These instruments replicate the mechanical properties of human vascular tissue, enabling realistic simulations that improve psychomotor skills and reduce training time for medical practitioners.

Resolved Analytics

Grant in 2020
Resolved Analytics is a professional engineering company that focuses on partnering with clients to enhance their development processes. The company aims to reduce development cycle times and costs while improving product design and troubleshooting existing designs. It specializes in computational engineering, offering services such as fluid-structure interactions, electrodynamics, magnetics, discrete element modeling, and computational fluid dynamics. By leveraging advanced simulation techniques, Resolved Analytics provides state-of-the-art visualizations and results that help businesses achieve their engineering goals and desired outcomes effectively.

Electro Magnetic Applications

Grant in 2019
EMA is a leading developer of technologies for engineering simulation. EMA’s engineering specialty is in applied electromagnetics. In this domain, EMA provides software and services to promote the design, certification, and performance of our customers’ products.

INFINI D Learning

Grant in 2019
Infini-D Learning gives pupils the chance to creatively put what they learn in the classroom into practice. Each student's understanding of classroom material is tested in several subject areas with creative technical and social skill training through game-like simulation modules, compelling team assignments, and immersive surroundings. When a teacher uses it, they have access to an application that keeps them involved in the learning process, gives them the ability to teach their lessons, and brings the subject matter to life in a way that has never been possible before.

Filament Games

Grant in 2019
Filament Games is a digital studio focused on the development of educational video games. The company creates award-winning digital learning games that aim to make education engaging and effective. Filament specializes in designing gameplay mechanics that accurately represent educational content, allowing players to acquire real-world knowledge through interactive play. One of their notable projects is RoboCo, a virtual robotics sandbox that facilitates fun and accessible engineering education. By blending entertainment with learning, Filament Games enhances the educational experience for players of all ages.

Sama Learning

Grant in 2018
Sama Learning is an innovative educational platform that focuses on enhancing the learning experience for college students by shifting the traditional educational paradigm. It specializes in developing a virtual reality (VR) learning environment that emphasizes science, technology, engineering, and mathematics (STEM) education. Through realistic and immersive virtual simulations, the platform allows students to engage with course material in an interactive manner, facilitating self-paced learning. This approach has been shown to result in a significant improvement in academic performance, with students achieving a full-letter grade increase in their studies.

Teton Simulation

Grant in 2018
Teton Simulation is a software company that specializes in the automatic validation and optimization of 3D printing parameters. The company's technology aims to streamline the traditional print-break-repeat prototyping cycle, thereby accelerating product development and lowering production costs. By leveraging its advanced software, users can enhance their applications through structural behavior analysis and progressive failure analysis, ultimately improving efficiency in the 3D printing process.

eGrove Education

Grant in 2018
eGrove Education is a software company focused on enhancing spatial visualization skills through its application, Spatial Vis. This educational tool is designed to support students in Engineering, Career and Technical Education (CTE), and other disciplines by providing online lessons in freehand sketching, 2D rotation, 3D drawing, orthographic views, tetrominoes, and flat patterns. The software features an automatic grading system, personalized feedback, an incentive system based on stars, animated hints, and a teacher interface, allowing students to engage with the material independently and improve their academic performance. By promoting these essential skills, eGrove Education aims to positively impact students' GPAs and graduation rates.

Simpetus

Grant in 2018
Simpetus specializes in providing advanced electromagnetic simulation tools aimed at enhancing research and development for enterprises and entrepreneurs. The company has developed a business simulation software platform that facilitates the launch and deployment of electromagnetic simulations. By utilizing a Python API, Simpetus enables photonics scientists and engineers to conduct efficient electromagnetic design and modeling. This platform is designed to streamline the simulation process, allowing users to obtain rapid results and support innovative discoveries in technology and research.

LightStanza

Grant in 2017
LightStanza is a startup based in Boulder, Colorado that makes the software LightStanza, a web application for daylight simulations. Light regulates the way they eat, sleep, live, work and play. Yet in design, daylighting is often overlooked, and almost always oversimplified. It is either misunderstood or under-utilized, both as a dynamic spatial element of a room, and in the overall energy efficiency of a building. Their founder set out to create a best-in-class daylight tool that everyone can use. Therefore, LightStanza is unique in its focus on daylighting as a piece of the green building puzzle. They know that daylight can’t be represented by a single number, so they offer several analysis options, each of which tells a different piece of the story. They address daylight alone so that they can get it right. They compute annual metrics, offer space-by-space scores for the LEED Daylight Credit, pinpoint areas of potential glare, and more, all with the precision and accuracy that only a focused tool can offer. They are not about developing “green” software, but about bringing awareness to a troubled environment by looking at light.

Flexcompute

Grant in 2017
FlexCompute is an IT company based in Boston, Massachusetts, established in 2016. It specializes in advanced computer simulation technology aimed at accelerating research and development in computing. The company develops proprietary R&D solvers that enhance innovation and efficiency, particularly for clients in the quantum computing sector. By providing simulation schemes that facilitate the design of complex quantum circuits, FlexCompute enables its clients to shorten calculation times and drive advancements in their technological pursuits.

Teton Simulation

Grant in 2017
Teton Simulation is a software company that specializes in the automatic validation and optimization of 3D printing parameters. The company's technology aims to streamline the traditional print-break-repeat prototyping cycle, thereby accelerating product development and lowering production costs. By leveraging its advanced software, users can enhance their applications through structural behavior analysis and progressive failure analysis, ultimately improving efficiency in the 3D printing process.

eGrove Education

Grant in 2016
eGrove Education is a software company focused on enhancing spatial visualization skills through its application, Spatial Vis. This educational tool is designed to support students in Engineering, Career and Technical Education (CTE), and other disciplines by providing online lessons in freehand sketching, 2D rotation, 3D drawing, orthographic views, tetrominoes, and flat patterns. The software features an automatic grading system, personalized feedback, an incentive system based on stars, animated hints, and a teacher interface, allowing students to engage with the material independently and improve their academic performance. By promoting these essential skills, eGrove Education aims to positively impact students' GPAs and graduation rates.

SimQuest

Grant in 2016
SimQuest develops advanced biomedical simulators, serious games, and advanced distributed learning applications for medical training and is involved with injury database development and analysis. They provide healthcare professionals with tools to enable them to develop their skills without putting patients at risk.

Filament Games

Grant in 2016
Filament Games is a digital studio focused on the development of educational video games. The company creates award-winning digital learning games that aim to make education engaging and effective. Filament specializes in designing gameplay mechanics that accurately represent educational content, allowing players to acquire real-world knowledge through interactive play. One of their notable projects is RoboCo, a virtual robotics sandbox that facilitates fun and accessible engineering education. By blending entertainment with learning, Filament Games enhances the educational experience for players of all ages.

Simpetus

Grant in 2016
Simpetus specializes in providing advanced electromagnetic simulation tools aimed at enhancing research and development for enterprises and entrepreneurs. The company has developed a business simulation software platform that facilitates the launch and deployment of electromagnetic simulations. By utilizing a Python API, Simpetus enables photonics scientists and engineers to conduct efficient electromagnetic design and modeling. This platform is designed to streamline the simulation process, allowing users to obtain rapid results and support innovative discoveries in technology and research.

Syandus

Grant in 2016
Syandus Inc. is a company that specializes in intelligent simulation learning technology tailored for the pharmaceutical sector. Based in Exton, Pennsylvania, it offers a range of products, including the Virtual Conventions platform, which employs responsive technology to assist patients, and the Medical Scenario Simulator, designed for clinicians to practice clinical decision-making in a virtual setting. Syandus also provides a technology platform aimed at enhancing promotional experiential learning and multichannel marketing for pharmacies. This platform helps pharmacies boost sales, influence prescription behaviors, and connect more effectively with healthcare providers. Established in 2001, Syandus seeks to transform how healthcare professionals, students, and patients comprehend life science and medical concepts through innovative technology and engaging learning experiences.

Intact Solutions

Grant in 2016
Intact Solutions is an interoperability platform that addresses some of the most significant barriers to the widespread adoption of analysis and simulation, where billions of dollars are currently being spent to address analysis and simulation interoperability issues. The platform generates all necessary data and procedures for use as input and output to a variety of open-source and commercial analysis and simulation codes that operate directly on native geometry and material models without the need for manual data preparation, preprocessing, or conversion.

LightStanza

Grant in 2015
LightStanza is a startup based in Boulder, Colorado that makes the software LightStanza, a web application for daylight simulations. Light regulates the way they eat, sleep, live, work and play. Yet in design, daylighting is often overlooked, and almost always oversimplified. It is either misunderstood or under-utilized, both as a dynamic spatial element of a room, and in the overall energy efficiency of a building. Their founder set out to create a best-in-class daylight tool that everyone can use. Therefore, LightStanza is unique in its focus on daylighting as a piece of the green building puzzle. They know that daylight can’t be represented by a single number, so they offer several analysis options, each of which tells a different piece of the story. They address daylight alone so that they can get it right. They compute annual metrics, offer space-by-space scores for the LEED Daylight Credit, pinpoint areas of potential glare, and more, all with the precision and accuracy that only a focused tool can offer. They are not about developing “green” software, but about bringing awareness to a troubled environment by looking at light.

Flexcompute

Grant in 2015
FlexCompute is an IT company based in Boston, Massachusetts, established in 2016. It specializes in advanced computer simulation technology aimed at accelerating research and development in computing. The company develops proprietary R&D solvers that enhance innovation and efficiency, particularly for clients in the quantum computing sector. By providing simulation schemes that facilitate the design of complex quantum circuits, FlexCompute enables its clients to shorten calculation times and drive advancements in their technological pursuits.

NEVA Electromagnetics

Grant in 2015
NEVA Electromagnetics is a biotech firm that offers antenna hardware design consultation as well as creative computational electromagnetics simulation tools capable of accurately modeling complex problems across the frequency spectrum, from DC to RF. They provide fully configurable products that are appropriate for commercial, research, and educational settings.

Impulsonic

Grant in 2015
Impulsonic develops physics-based audio for video games and VR.

Impulsonic

Grant in 2015
Impulsonic develops physics-based audio for video games and VR.

Intact Solutions

Grant in 2014
Intact Solutions is an interoperability platform that addresses some of the most significant barriers to the widespread adoption of analysis and simulation, where billions of dollars are currently being spent to address analysis and simulation interoperability issues. The platform generates all necessary data and procedures for use as input and output to a variety of open-source and commercial analysis and simulation codes that operate directly on native geometry and material models without the need for manual data preparation, preprocessing, or conversion.

VorCat

Grant in 2013
VorCat specializes in fluid flow prediction software, focusing on the simulation, design, and analysis of complex fluid flow applications. The company has developed advanced Computational Fluid Dynamics (CFD) tools that utilize grid-free methods to predict turbulent flow. This innovative approach addresses the shortcomings of existing fluid prediction methods, particularly in industries such as automotive, aerospace, green energy, maritime, electronics, and biomedical applications. By enhancing the accuracy of turbulent flow predictions, VorCat enables these sectors to improve their design processes and overcome engineering challenges related to fluid dynamics.

Impulsonic

Grant in 2013
Impulsonic develops physics-based audio for video games and VR.

AgentSheets

Grant in 2013
AgentSheets, Inc. is an educational software company in Boulder, Colorado. Our authoring tools and curricula truly reflect years of research in human-computer interaction, end-user programming, and simulation/modeling tools. Our mission is to foster K-12 student participation in STEM fields through motivational applications based on AgentSheets' unique technologies. We provide teachers and students with innovative instruction in computational thinking and design that motivates them to explore computer science education and careers. AgentSheets, Inc. is an international leader in educational technology, innovative educational solutions, and measureable results!

i-Human Patients

Grant in 2013
i-Human Patients, Inc. specializes in creating virtual medical training products, notably its i-Human Patients platform, which is designed for educational use in medical schools. This cloud-based, interactive platform allows educators and students to engage in active learning methodologies, enhancing training outcomes and adherence to clinical protocols. The platform simulates complete medical patient encounters, guiding users through processes such as history taking, physical examinations, differential diagnosis, and test evaluation. By integrating clinical experience early in medical education, i-Human Patients equips students and practitioners with essential patient assessment and diagnostic reasoning skills, ultimately preparing them for real-world clinical encounters and improving the quality of care in the healthcare industry.

MolySym

Grant in 2013
MolySym, Inc. is a company based in Cambridge, Massachusetts, that specializes in developing computer interface products for the manipulation and simulation of molecular systems. It offers molecular modeling systems primarily aimed at the education sector, facilitating research and training through advanced technology solutions. The company provides various services, including multiple molecular representations, investigations, interpretation, visualization, and research and development, contributing to advancements in molecular science and education.

ExploreLearning

Grant in 2013
Explorelearning is educational firm for class of 3 to 12 level, it's provide math and science simulation. ExploreLearning® believes all students can succeed in math and science. Our online solutions bring effective, research-proven instructional strategies to classrooms around the world. Gizmos

Stage III

Grant in 2013
Stage III provides realistic veterinary surgery and anesthesia training with evidence based techniques. They create custom veterinary medical scenarios to increase proficiency in their clinical teaching.

NanoMEMS Research

Grant in 2012
NanoMEMS Research develops and conducts research to conceive, develop, and commercialise RF MEMS and nanotechnology devices, circuits, systems, and applications. They offer advanced analysis, modeling, simulation, design, and prototyping services.

Filament Games

Grant in 2012
Filament Games is a digital studio focused on the development of educational video games. The company creates award-winning digital learning games that aim to make education engaging and effective. Filament specializes in designing gameplay mechanics that accurately represent educational content, allowing players to acquire real-world knowledge through interactive play. One of their notable projects is RoboCo, a virtual robotics sandbox that facilitates fun and accessible engineering education. By blending entertainment with learning, Filament Games enhances the educational experience for players of all ages.

The MammaCare Foundation

Grant in 2012
The MammaCare Foundation provides clinical certification services and high fidelity simulation based training. Their customers inquiries are addressed through phone, email, and online applications.

CoolCAD Electronics

Grant in 2012
CoolCAD Electronics, LLC is a CAD and custom electronics design firm that specializes in satisfying non-mainstream electronic design applications. Our expertise ranges from nanostructure and device modeling, design and analysis, to integrated circuit design and layout, and all the way to printed circuit board level electronics development. More specifically our thrust is concentrated on three areas: 1) Semiconductor fabrication and characterization, 2) electronics design and prototyping, and 3) Circuit modeling and simulation.

NEVA Electromagnetics

Grant in 2012
NEVA Electromagnetics is a biotech firm that offers antenna hardware design consultation as well as creative computational electromagnetics simulation tools capable of accurately modeling complex problems across the frequency spectrum, from DC to RF. They provide fully configurable products that are appropriate for commercial, research, and educational settings.

The Learning Chameleon

Grant in 2012
The Learning Chameleon, Inc. is a worldwide leader in developing models of how students develop 21st century problem solving skills. The company's IMMEX™ software assisted learning in more than 150,000 students in classrooms internationally by integrating these multimedia simulations into a unique web-based learning platform for modeling strategic thinking and problem solving. These models help teachers teach, students learn, and administrators make informed educational decisions through the continual, and real-time evaluation problem solving progress. We accomplish this by leveraging existing proprietary libraries of tasks, data sets and advance intelligence-derived performance models, and then extending them with cutting-edge technologies such as second-by-second Cognitive Electrophysiology models. During the past several years The Learning Chameleon, Inc. has applied these technologies and developed Team NeuroDynamics. While most people can recognize if a team is in the groove or out of synch, it is more difficult to predict when changes in the state will occur, yet having this ability would be important for dynamically adapting team performance. If we can predict when a team is going out of synch, we can provide real-time feedback to help prevent performance errors, lapses in communication or lapses in attention. In this way the company, like its name sake successfully blends within and across educational, training and assessment environments.

Butterfly Haptics

Grant in 2004
Butterfly Haptics specializes in the development and supply of advanced haptic interface systems aimed at enhancing research and application in various fields. The company focuses on creating high-performance products that overcome common limitations found in traditional mechanical haptic systems, such as friction and backlash. Utilizing innovative technology, Butterfly Haptics enables users to experience a highly realistic sense of touch when interacting with virtual or remote environments. Their systems allow users to grasp rigidly attached handles that are levitated by powerful magnetic fields, providing an exceptionally high-fidelity haptic experience that is beneficial for both research and development purposes.
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