National Science Foundation

The National Science Foundation is an independent federal agency in the United States that funds and supports research and education in science and engineering. It funds fundamental research and education across all fields of science and engineering and administers non-dilutive funding programs to aid early‑stage technology development, helping translate discoveries into commercially viable products and services. Through grants and fellowships, the NSF supports researchers, educators, and startups, contributing to innovation and U.S. competitiveness. The agency operates with a substantial budget to advance science, engineering, and STEM education nationwide.

James Donlon

Program Director

Sean L. Jones

Assistant Director for Mathematical and Physical Sciences

Debasis Majumdar

Program Director

Graciela Narcho

Staff Associate

Sethuraman Panchanathan

Director

Past deals in Nanotechnology

Eascra Biotech

Grant in 2025
Eascra Biotech specializes in developing DNA-inspired, nanoparticle-based delivery systems for targeted therapeutic treatment. Their platform, based on Janus base nanomaterials, encapsulates and stabilizes various therapeutic agents like mRNA, siRNA, proteins, and gene-editing tools, enabling precise delivery to hard-to-reach tissues such as cartilage, kidneys, and solid tumors. This approach enhances therapeutic efficacy, reduces systemic exposure, and preserves bioactivity, offering a low-cost, scalable alternative to existing treatments for chronic conditions.

Novaurum Biosciences

Grant in 2025
Novaurum Biosciences develops AuPEC, a proprietary cell-based encapsulation technology for implanted orthopedic devices. This innovative approach combines microbiology and nanotechnology to create nano-biological coatings that significantly reduce infection rates and promote healing.

Amphix Bio

Grant in 2024
Amphix Bio specializes in the development of therapeutic materials aimed at advancing regenerative medicine. The company focuses on creating nanofiber materials that replicate the structure and dynamic properties of human tissues. By integrating biological signals into these materials, Amphix Bio effectively guides cells to initiate regenerative processes. This innovative approach enables the development of therapies for repairing various tissues, including bone, cartilage, muscle, cardiovascular tissues, and nervous system components such as the brain and spinal cord. With expertise in materials science, stem cell biology, biomolecular design, engineering, medical physics, and informatics, Amphix Bio seeks to translate its promising preclinical and clinical trial results into viable treatment options.

Nanopath

Grant in 2024
Nanopath is a molecular diagnostics company that develops innovative platforms for rapid disease diagnosis. Its technology enables point-of-care testing, eliminating the need for nucleic acid amplification and supporting multiplexed detection. This allows patients and healthcare providers to access accurate diagnostic results within standard office visits, improving healthcare outcomes.

New Jersey Institute of Technology

Grant in 2023
New Jersey Institute of Technology (NJIT) is a research-focused university offering over 70 undergraduate and 15 graduate programs in technology, engineering, biological sciences, computer sciences, and related fields. NJIT is renowned for its state-of-the-art campus, highly qualified faculty, and pioneering research collaborations with local industries. The university's competitive admission process ensures high academic standards, with many students receiving financial aid.

Avisi Technologies

Grant in 2023
Avisi Technologies Inc. is a Philadelphia-based company founded in 2017 that specializes in developing innovative solutions for glaucoma treatment. Its primary product, VisiPlate, is a next-generation, nanotechnology-enabled aqueous shunt designed to prevent blindness caused by glaucoma. Through its advanced technology, Avisi Technologies aims to enhance the effectiveness of glaucoma management and improve patient outcomes.

Kismet Technologies

Grant in 2023
Kismet Technologies specializes in innovative material technologies for infection control on surfaces. Its flagship product, NanoRAD, employs a proprietary combination of cerium oxide particles and chitosan to provide long-lasting antimicrobial protection, odor management, and UV protection. This enables manufacturers to integrate these properties into coatings, textiles, and other materials, enhancing safety, durability, and hygiene.

Superior Nano

Grant in 2022
Superior Nano is a skincare manufacturer specializing in topical products that enhance skin appearance and health. Utilizing proprietary nanotechnology, their serums and moisturizers target aging, radiance, and firmness, offering consumers an effective alternative to invasive procedures.

AeroShield

Grant in 2022
AeroShield specializes in the production of super-insulating, nanoporous glass materials designed for energy-efficient windows. Utilizing silica aerogel, AeroShield's products offer optical clarity akin to traditional glass while delivering superior insulation, making them 50% more effective than conventional double-pane windows. This innovative approach not only enhances thermal comfort but also significantly improves energy performance, allowing window manufacturers to meet sustainability and compliance objectives. Additionally, the payback period for AeroShield's materials is up to five times faster than that of similarly performing windows, making them a compelling choice for the modern market.

Sunchem

Grant in 2022
Sunchem specializes in the development of environmentally sustainable nano filters designed for waste and wastewater management. The company's innovative technology focuses on the selective capture of metals from complex water mixtures, offering a superior alternative to existing separation methods. Targeting high-value markets such as water purification, energy, and critical metal extraction, Sunchem's solutions enable industries to enhance water quality in a cost-effective and energy-efficient manner. Additionally, these filters allow clients to derive value from their waste streams, thereby promoting both economic and environmental benefits.

NanoDian

Grant in 2022
NanoDian is a nanotechnology company focused on developing and commercializing advanced lithium-ion battery materials, specifically cathode materials. The company employs patented laboratory-developed technology to create next-generation batteries that address critical challenges in the industry, such as improving life cycles, enhancing charge rates, increasing safety, and reducing costs. NanoDian's innovations aim to benefit a range of applications in both portable and stationary energy storage systems, including electric vehicles and microgrids. Through its commitment to cutting-edge research and development, NanoDian seeks to contribute significantly to the evolution of energy storage solutions.

MFNS

Grant in 2022
MFNS specializes in industrial water treatment. It offers consulting services for oil and contaminant separation, and develops custom OHM membranes or sponges tailored to specific industry needs.

NanoResearch

Grant in 2022
NanoResearch is a technology company specializing in the research, design, development, and commercialization of advanced materials and energy storage solutions. The company focuses on creating innovative products, including energy storage devices, mechanical smart lighting systems, and nanobiomedical applications. By leveraging its nanotechnology expertise, NanoResearch aims to provide effective solutions to governments, businesses, and non-profit organizations, helping them to quickly enter the market with cutting-edge technologies. The company is committed to driving advancements in energy storage and smart materials, positioning itself as a key player in the development of breakthrough technologies that address contemporary challenges in these fields.

Amphix Bio

Grant in 2022
Amphix Bio specializes in the development of therapeutic materials aimed at advancing regenerative medicine. The company focuses on creating nanofiber materials that replicate the structure and dynamic properties of human tissues. By integrating biological signals into these materials, Amphix Bio effectively guides cells to initiate regenerative processes. This innovative approach enables the development of therapies for repairing various tissues, including bone, cartilage, muscle, cardiovascular tissues, and nervous system components such as the brain and spinal cord. With expertise in materials science, stem cell biology, biomolecular design, engineering, medical physics, and informatics, Amphix Bio seeks to translate its promising preclinical and clinical trial results into viable treatment options.

Nostopharma

Grant in 2022
Nostopharma specializes in treating pathologic bone growth to prevent rare bone diseases. Their nanoparticle drug delivery system aids patients in forming new bone following surgeries, burns, injuries, and other traumas, enabling healthcare providers to enhance clinical outcomes.

Future Semiconductor

Grant in 2022
Future Semiconductor specializes in developing gallium nitride (GaN) substrates for light-emitting diodes. Their proprietary technology enables infinite reuse of the parent wafer and fast layer release, offering clients a cost-effective solution for growing high-quality single-crystalline semiconductors on graphene.

NanoFlex Power

Grant in 2022
NanoFlex Power Corporation is a Scottsdale, Arizona-based company that specializes in the research, development, commercialization, and licensing of advanced photovoltaic technologies, particularly focusing on thin-film solar products. Established in 1994, the company holds a global license to sublicense intellectual property from its sponsored research programs, resulting in a robust portfolio of issued and pending patents in the United States and internationally. Its innovative technologies include Gallium Arsenide-based solar thin films and organic photovoltaic materials designed for ultra-thin applications. These advancements enable various uses, such as portable and off-grid power generation, building-integrated photovoltaics, semi-transparent solar glazing for windows, and solar films for automobiles and consumer electronics. NanoFlex Power aims to provide high-performance solutions that are lightweight, flexible, and cost-effective, thereby enhancing the accessibility and versatility of solar energy applications across multiple sectors.

Nanopath

Grant in 2021
Nanopath is a molecular diagnostics company that develops innovative platforms for rapid disease diagnosis. Its technology enables point-of-care testing, eliminating the need for nucleic acid amplification and supporting multiplexed detection. This allows patients and healthcare providers to access accurate diagnostic results within standard office visits, improving healthcare outcomes.

Coreless Technologies

Grant in 2021
Coreless Technologies specializes in the design and manufacture of hollow metal nanoparticles aimed at improving the performance of nano-enabled devices. The company utilizes a continuous flow process to produce these nanoparticles, allowing for precise control over their size, shape, and optical properties. This technology is particularly beneficial for military applications in potentially contaminated areas, providing essential support in environments with limited healthcare access. Additionally, Coreless Technologies' innovations extend to agricultural sectors, where they facilitate the detection of plant-based diseases, thereby enhancing overall farming efficiency and safety.

American Nanotechnologies

Grant in 2021
American Nanotechnologies specializes in developing innovative systems for large-scale purification of high-value dielectric materials.

Zymosense

Grant in 2021
Zymosense specializes in automated aqueous two-phase extraction technology for efficient, scalable sorting of chiral-pure single-walled carbon nanotubes. Its platform enables various industries to access rapid evaluation, discovery, and design of new enzymes.

TruSpin Nanomaterial Innovation

Grant in 2021
TruSpin specializes in the mass production of unique nanofibers using its proprietary A/C electrospinning process. These nanofibers are currently employed as additives in battery chemicals, significantly enhancing energy density.

Valgotech

Grant in 2021
Founded in 2018, Valgotech is a technology company based in Fishers, Indiana. It specializes in advanced materials and energy storage systems, aiming to make energy consumption more sustainable and affordable.

Minerva Lithium

Grant in 2021
Minerva Lithium, founded in 2020 in Greensboro, North Carolina, focuses on advancing critical mineral extraction technologies. The company has developed a proprietary nano mosaic membrane filter system that enhances the extraction of lithium from non-traditional water resources. This innovative approach aims to improve lithium recovery rates and support the clean energy sector, as well as the automotive and technology industries, by providing high-grade pure minerals essential for various applications. In addition to boosting lithium availability, Minerva's methods also facilitate the recovery of usable water, contributing to sustainable practices in mineral extraction.

NanoPattern Technologies

Grant in 2021
NanoPattern Technologies develops photopatternable quantum dot formulations and nanoparticle inks for patterning high-resolution quantum dot downconverter layers, enabling displays for televisions, smartphones, wearables, augmented reality and virtual reality. Founded in 2019 and headquartered in Chicago, Illinois, the company’s direct nanoparticle lithography process is compatible with conventional photolithography and supports parallel patterning, helping manufacturers produce advanced display systems.

Ecate

Grant in 2021
Ecate is a Los Angeles-based company established in 2020, focused on developing innovative medical devices that create organo-robotic interfaces. The company aims to enhance human capabilities by integrating machine intelligence with biological systems. Specifically, Ecate is working on advanced neural interfaces that utilize nanoparticles and nanotechnology to facilitate communication between injured sites and the central nervous system. By employing customized nanopatterned electrodes, Ecate's technology seeks to restore sensory and motor functions for paralyzed patients, thereby helping them regain control over their lost abilities.

Serinus Labs

Grant in 2021
Serinus Labs, Inc. is a manufacturer of nano-scale silicon gas sensors, established in 2017 and based in Berkeley, California. The company specializes in developing integrated chip-scale gas sensors tailored for various industries, including health and safety, automotive, consumer electronics, and healthcare. Serinus Labs offers custom solutions that address both existing and emerging market needs. In particular, the company focuses on providing ultra-low-power trace gas sensors for Li-ion battery state-of-health monitoring, which enhances battery intelligence in electric vehicles. Through its innovative technology, Serinus Labs aims to meet critical demands across strategic markets.

NanoSpy

Grant in 2021
Founded in 2017, NanoSpy specializes in rapid pathogen detection using proprietary biosensors. These sensors can detect live bacteria at low concentrations within 20 minutes, without the need for time-consuming enrichment processes or laboratory requirements.

Battery Streak

Grant in 2021
Battery Streak specializes in advanced battery technology that significantly enhances charging efficiency and performance. The company develops batteries capable of charging in under 10 minutes, offering high power discharge while maintaining a longer lifespan compared to conventional lithium-ion batteries. Utilizing innovative nanostructured materials, Battery Streak's technology minimizes the travel distance of lithium ions during the charging process. This advancement not only enables users to quickly charge their electronic devices but also helps businesses reduce downtime, thereby improving overall productivity. The batteries are engineered to operate safely without overheating, making them a promising alternative in the energy storage market.

Nano PharmaSolutions

Grant in 2021
Nano PharmaSolutions specializes in enhancing the bioavailability of insoluble drugs through its proprietary nanoformulation technology. The company has developed an innovative phase-transition technology platform that significantly improves the solubility of BCS 2 and BCS 4 active pharmaceutical ingredients (APIs) without the need for excipients, which are typically used in traditional processes like spray-dry dispersion and emulsification. By vaporizing the API and depositing it onto a carrier molecule, Nano PharmaSolutions enables the production of nanoparticles that can be processed into various dosage forms. Additionally, the company focuses on delivering neurodegenerative therapeutics directly to the brain via an intranasal route, facilitating a rapid onset of action and enhancing safety profiles. Their pipeline includes treatments for conditions such as Parkinson's disease, peripheral neuropathy, and substance abuse disorders, positioning Nano PharmaSolutions as a key player in the field of nanomedicine.

Novel Farms

Pre Seed Round in 2021
Novel Farms, Inc. is a Berkeley, California-based company founded in 2020 that specializes in the production of cell-based meat delicacies. It focuses on developing cruelty-free, low-cost, and tunable bioscaffolds through microbial fermentation and proprietary tissue engineering technology. The company's mission is to create gourmet meat alternatives that replicate the taste and texture of conventional meats, appealing to a new generation of conscious consumers. By producing whole-muscle cuts of cultivated meat, Novel Farms aims to make synthetic meat-based delicacies accessible and desirable, transforming the consumption of cell-based meat into a sought-after culinary experience.

Novel Farms

Grant in 2021
Novel Farms, Inc. is a Berkeley, California-based company founded in 2020 that specializes in the production of cell-based meat delicacies. It focuses on developing cruelty-free, low-cost, and tunable bioscaffolds through microbial fermentation and proprietary tissue engineering technology. The company's mission is to create gourmet meat alternatives that replicate the taste and texture of conventional meats, appealing to a new generation of conscious consumers. By producing whole-muscle cuts of cultivated meat, Novel Farms aims to make synthetic meat-based delicacies accessible and desirable, transforming the consumption of cell-based meat into a sought-after culinary experience.

inSomaBio

Grant in 2021
InSoma Bio integrates biology and materials science to solve problems in tissue engineering and regenerative medicine. It offers genetically engineer protein-based materials that can mimic the naturally found elastin found in extracellular tissues. The company also offers reconstructive plastic surgeries and injectable materials.

Partillion Bioscience

Grant in 2021
Partillion Bioscience is a life science company developing a platform for functional single-cell analysis. This platform enables rapid compartmentalization and analysis of millions of single cells to probe biological functions such as secreted proteins, facilitating the development of advanced therapies for conditions like cancer, autoimmune disorders, and infectious diseases.

QDIR

Grant in 2021
QDIR is a nanomaterials company that specializes in the development of infrared detectors and imaging arrays tailored for industrial and defense applications. The company focuses on creating shortwave and mid-wave infrared detectors that offer enhanced imaging solutions across various sectors, including commercial, medical, industrial, and military markets. By leveraging proprietary nanomaterial technology, QDIR achieves high sensitivity and low noise in its products, which results in superior imaging performance compared to traditional infrared detectors. This innovative approach positions QDIR as a key player in providing advanced detection and imaging capabilities to its diverse customer base.

Irradiant Technologies

Grant in 2021
Founded in 2020, Irradiant Technologies specializes in developing advanced lithography techniques for high-throughput microfabrication. Headquartered in Cambridge, Massachusetts, the company's core technology enables ultrafast three-dimensional assembly of diverse materials with nanoscale precision, facilitating innovation in photonic and optical components for telecommunications, computation, and sensing.

Ballydel Technologies

Grant in 2021
Ballydel Technologies is a research and development company founded in 2018 and headquartered in Newark, Delaware. It focuses on creating innovative material and technology solutions aimed at various sectors, including space exploration, defense, public health, and societal applications. The company specializes in areas such as nanocomposite design and synthesis, hypersonic materials and manufacturing, as well as pharmaceutical tagging and authentication. By providing advanced materials and technologies, Ballydel Technologies enables clients to enhance existing products and optimize their manufacturing processes.

AeroShield

Grant in 2021
AeroShield specializes in the production of super-insulating, nanoporous glass materials designed for energy-efficient windows. Utilizing silica aerogel, AeroShield's products offer optical clarity akin to traditional glass while delivering superior insulation, making them 50% more effective than conventional double-pane windows. This innovative approach not only enhances thermal comfort but also significantly improves energy performance, allowing window manufacturers to meet sustainability and compliance objectives. Additionally, the payback period for AeroShield's materials is up to five times faster than that of similarly performing windows, making them a compelling choice for the modern market.

CelluDot

Grant in 2021
CelluDot is a biotechnology company developing innovative suspension and emulsion technologies. Its core platform aims to tackle agrochemical drift, offering farmers an affordable and effective adjuvant that minimizes vapor and particle drift of herbicides like dicamba.

Coreshell Technologies

Grant in 2021
Founded in 2017, Coreshell Technologies specializes in advanced materials engineering for lithium-ion batteries. The company focuses on enhancing battery performance and lifespan through its proprietary nanolayer thin-film coating technology, catering primarily to the electric vehicle and grid storage markets.

Hummingbird Nano

Grant in 2021
Hummingbird Nano is a commercial company specializing in the development of ultra-smooth, circular channel microfluidic chips crafted from a single solid form. The company's innovative technology enables the creation of new products that surpass current manufacturing capabilities, while also making existing high-priced products more accessible. By combining the speed of injection molding with the flexibility of 3D printing, Hummingbird Nano is transforming the production of microfluidic chips and micro-optics. Their precision engineering equipment facilitates the production and assembly of micro-scale components with nanometer-scale accuracy, allowing clients to achieve improved performance and design flexibility in their products. Hummingbird Nano's focus on affordable and high-quality manufacturing is poised to spur innovation and contribute positively to society.

SolMem

Grant in 2021
SolMem is a technology company that develops a nanotechnology-enabled photothermal membrane for water distillation. The membrane uses a nanocomposite coating that absorbs sunlight and converts it to heat, allowing efficient desalination and purification of any water source, including unconventional waters. Founded in 2017, the company is based in Houston, Texas.

Vapor Cell Technologies

Grant in 2021
Founded in 2020, Vapor Cell Technologies specializes in developing ultra-compact vapor cells that enable distance detection with sub-nanometer accuracy. Headquartered in Boulder, Colorado, the company's technology converts lasers into wavelength standards and facilitates precise length and optical frequency measurements.

Nanoxort

Grant in 2021
Nanoxort develops diffusive magnetic fractionation technology to precisely tailor the properties of magnetic nanomaterials. The company also pursues MRI contrast solutions in which a contrast agent is administered to improve image resolution and reduce gadolinium exposure, addressing safety concerns for patients who require repeated scans and those with kidney impairment. Founded in 2018 and based in Auburn, Alabama, Nanoxort aims to enable safer, higher quality MRI imaging by controlling magnetic nanoparticle behavior and minimizing potential toxic effects associated with gadolinium-based contrast agents.

Souvie Biodelivery

Grant in 2021
Founded in 2018, Souvie Biodelivery specializes in developing innovative drug delivery systems using engineered exosomes. Its platform aims to enhance biocompatibility, reduce immunogenicity, and improve specificity for targeted treatments across various diseases like immuno-inflammation, cancer, and neurological disorders.

GeoMat

Grant in 2021
GeoMat is a nanotechnology company that focuses on oil remediation. The company was founded in 2014 and is headquartered in Columbia, South Carolina.

Blueshift Optics

Grant in 2021
Blueshift Optics is a developer of innovative organic scintillator technology designed for radiation detection applications. The company has created a versatile organic scintillator that excels in neutron detection while offering high gamma discrimination. This advancement in scintillator materials aims to enhance the capabilities of the radiation detection community. Blueshift Optics focuses on delivering quality performance through its products, which cater to a diverse range of applications, ultimately enabling physicists to utilize efficient organic glass scintillators in their work.

BioAesthetics

Grant in 2021
BioAesthetics develops tissue-engineered nipple-areolar complex grafts to support breast reconstruction after mastectomy. The graft is designed as a scaffold for the patient's own cells to populate and regenerate the nipple and areola during reconstruction, aiming to improve cosmetic and reconstructive outcomes. The company originated as a Tulane University spin-out and was founded in 2015.

Minerva Lithium

Pre Seed Round in 2021
Minerva Lithium, founded in 2020 in Greensboro, North Carolina, focuses on advancing critical mineral extraction technologies. The company has developed a proprietary nano mosaic membrane filter system that enhances the extraction of lithium from non-traditional water resources. This innovative approach aims to improve lithium recovery rates and support the clean energy sector, as well as the automotive and technology industries, by providing high-grade pure minerals essential for various applications. In addition to boosting lithium availability, Minerva's methods also facilitate the recovery of usable water, contributing to sustainable practices in mineral extraction.

General Engineering and Research

Grant in 2020
General Engineering and Research specializes in the development of nanotechnology-based systems aimed at both clinical and industrial processing applications. The company's innovative research portfolio includes functionalized nanoparticles and nano-sized capsules that serve various purposes, notably in polishing applications like chemical mechanical planarization. In addition to these polishing solutions, the company also focuses on applications in drug delivery and nano-sensors. By leveraging advanced nanomaterials, General Engineering and Research enables clients to enhance their business processes and achieve specific operational goals.

Electronic BioSciences

Grant in 2020
Electronic BioSciences specializes in developing high-precision instruments for research and sensing applications. They focus on combining advanced electronics with nanopore platforms to enable molecular and biophysical analysis, with a particular emphasis on reducing measurement noise.

NanoInnovations

Grant in 2020
NanoInnovations is a research and development company based in Sugar Land, Texas, established in 2014. The company specializes in the development of smart nanosensors that leverage machine learning for healthcare analytics. Its innovative platform technology is designed to analyze bio-fluids, including sweat and saliva, facilitating advancements in the management of conditions such as diabetes and heart failure. By providing real-time information, NanoInnovations empowers healthcare providers to enhance patient care and improve healthcare management outcomes.

ReVive Biotechnology

Grant in 2020
ReVive Biotechnology is a company dedicated to enhancing oxygen delivery to hypoxic tissues through the development of a nanobubble-based oxygen delivery platform. The primary focus of its research and development efforts is on treating Central Retinal Artery Occlusion (CRAO), a condition that mimics a stroke in the retina and can lead to irreversible blindness. By utilizing innovative nanotechnology, ReVive aims to improve treatment and diagnostic approaches for CRAO and potentially other ischemic retinal conditions, thereby contributing to advancements in ocular health and therapeutic options.

Nanomatronix

Grant in 2020
Nanomatronix operates an engineering platform that specializes in biotechnology, microelectronics, and nanotechnology. The company provides solutions tailored for the healthcare, energy, and defense sectors. Its offerings encompass the design, prototyping, packaging, screening, qualification, and production of application-specific integrated circuits, hybrid microcircuits, and fiber optic networking transceivers. These products are engineered for use in both terrestrial and harsh environments, facilitating the transition of innovative technologies in biomedical, chemical processing, microelectronics, nanomaterials, and photonics. Through its expertise, Nanomatronix aims to support advancements in critical industries.

Avisi Technologies

Grant in 2020
Avisi Technologies Inc. is a Philadelphia-based company founded in 2017 that specializes in developing innovative solutions for glaucoma treatment. Its primary product, VisiPlate, is a next-generation, nanotechnology-enabled aqueous shunt designed to prevent blindness caused by glaucoma. Through its advanced technology, Avisi Technologies aims to enhance the effectiveness of glaucoma management and improve patient outcomes.

ZeoVation

Grant in 2020
Founded in 2016, ZeoVation specializes in manufacturing nanozeolites and hierarchical zeolites. These materials enhance consumer products such as skincare lotions, sunscreens, laundry detergents, water softeners, and filtration systems by improving efficiency.

BENANOVA

Grant in 2020
BENANOVA develops safer antimicrobial products and eco-friendly materials for disinfectant, cosmetic, agricultural, and textile applications. Its Environmentally-benign Nanoparticles provide high efficacy with a degradable design, offering environmentally friendly replacements for silver nanoparticle antimicrobials and the potential to reduce chemical use in crop protection by up to 90%. The company also uses lignin-based, biodegradable materials from bio-renewable sources to support sustainable agriculture and specialty textiles, combining strong performance with reduced environmental impact.

Guardion

Grant in 2020
Guardion is a technology company specializing in advanced sensor technology, particularly in the development of radiation detectors that utilize the quantum properties of nanomaterials. This innovative approach allows Guardion to create low-cost, highly sensitive, and energy-efficient detectors suitable for large-scale deployment, especially in urban environments. The company focuses on applications that demand high sensitivity and miniaturization, providing analytical instruments and chemical detectors that serve various industries, including aerospace, healthcare, and national security. Guardion has received recognition for its contributions to the field, winning multiple awards such as the MassChallenge Gold Prize and the Technology in Space Prize from CASIS and Boeing. Additionally, the company participated in the inaugural cohort of the Techstars Autonomous Tech Accelerator, which is sponsored by the Air Force.

Metalmark Innovations

Grant in 2020
Metalmark Innovations, Inc. focuses on developing and delivering advanced 3D nanostructured coatings designed to treat airborne pollutants and toxins, enhancing indoor air quality. The company offers its innovative materials as additive coatings for various applications, including building materials and vehicle interiors, effectively addressing pollutants such as hydrocarbons, carbon monoxide, ozone, PM2.5, volatile organic compounds, odors, and germs. Its air cleaning technology employs catalytic materials that filter air with nanoscale precision, contributing to solutions for air pollution and climate change challenges. Founded in 2017 and headquartered in Boston, Massachusetts, Metalmark Innovations was previously known as Aircrew Technologies, Inc. before rebranding in January 2019.

42Bio

Grant in 2020
42Bio is a biomedical technology company based in Gainesville, Florida, founded in 2015. It specializes in developing innovative solutions in regenerative medicine and tissue engineering, aiming to overcome challenges in research and clinical application. The company combines magnetic nanotechnologies with bio-active molecules and biocompatible materials to enhance various processes, including gene transfection, bioreactor development, and the separation of cells and biomolecules. Its technologies facilitate advancements in cell and tissue culture, providing medical professionals with improved methods for lipid extraction and enabling independent flow separation in various applications. Through its work, 42Bio contributes to the advancement of regenerative medicine, enhancing the capabilities available to healthcare providers.

Kismet Technologies

Grant in 2020
Kismet Technologies specializes in innovative material technologies for infection control on surfaces. Its flagship product, NanoRAD, employs a proprietary combination of cerium oxide particles and chitosan to provide long-lasting antimicrobial protection, odor management, and UV protection. This enables manufacturers to integrate these properties into coatings, textiles, and other materials, enhancing safety, durability, and hygiene.

ACatechol

Grant in 2020
ACatechol, founded in 2016 and based in Pasadena, California, specializes in the development of biological-protein-based adhesives and biomimetic surface technologies. The company's innovative products are designed to prevent the spread of diseases by utilizing nanocomposite coatings and surface modifications applicable to various materials such as medical devices, implants, and textiles. These advanced coatings are effective in eliminating a wide range of bacteria and viruses, even in moist conditions. This capability enables the production of underwater glues, adhesives, coatings, and primers, offering a safer and more efficient alternative to traditional silane-based grafting methods, which can be slow, toxic, and inconsistent.

NanoSoft

Grant in 2020
NanoSoft is a cryogenic electron microscopy tool and instrument maker.

Kampanics

Grant in 2020
Kampanics is a research and development company based in Oak Ridge, North Carolina, specializing in microacoustic devices and piezomems technology. Founded by Kushal Bhattacharjee, the company focuses on providing innovative solutions in signal processing, sensing, and energy harvesting. By collaborating with academic associates, corporate partners, and domain experts, Kampanics aims to facilitate the development of new products and services that leverage its specialized technological expertise.

Celadyne

Grant in 2020
Celadyne Technologies, founded in 2018 and based in Chicago, Illinois, specializes in the development of advanced nanocomposite membranes for electrolyzers and fuel cells. These membranes are engineered to facilitate efficient heat and water management, addressing critical challenges in hydrogen production. By incorporating innovative technologies, Celadyne's membranes provide advantages akin to ceramic separators, including reduced hydrogen crossover, while maintaining performance under low humidity and elevated temperature conditions. This design enhances catalyst durability and supports the hydrogen economy by offering a cost-effective solution for energy applications.

Wildspark Technologies

Grant in 2020
WildSpark Technologies, founded in 2016 and based in Austin, Texas, specializes in the development of micro and nanoscale plasma devices. The company has created innovative propulsion technology that enables unmanned aerial vehicles (UAVs) to operate without propeller blades, enhancing precision and maneuverability. This technology allows drones and small air vehicles to take off and navigate in confined spaces, significantly reducing the risks associated with traditional propeller contact injuries. WildSpark Technologies aims to contribute to advancements in air taxi services and the broader UAV sector through its cutting-edge solutions.

Scintillation Nanotechnologies

Grant in 2020
Founded in 2018, Scintillation Nanotechnologies specializes in developing proprietary nanomaterials for detecting radioisotopes. Its core technology involves creating multiplexed nanoscale detectors and radioisotope-responsive nanoparticles, enabling direct measurement of radioisotope-labeled species.

Swift Coat

Grant in 2020
Swift Coat designs and manufactures nanoparticle-coating solutions in Arizona. Its versatile solution coats various surfaces, serving diverse markets including solar, military, consumers, industries, glazing, filtration, display, and sensors.

Rydberg Technologies

Grant in 2020
Rydberg Technologies is a research company founded in 2015 and based in Ann Arbor, Michigan, that focuses on quantum sensing, measurement, and imaging. The company develops and manufactures advanced quantum measurement devices designed for next-generation sensing and imaging applications. Its product offerings include sensor technology-based quantum measurement devices and electric-field and power sensors for microwaves, which utilize atomic vapors as quantum sensors. These technologies enable clients to effectively measure radio-frequency, microwave, millimeter-wave, and terahertz electric fields, positioning Rydberg Technologies at the forefront of innovation in the quantum measurement sector.

BENANOVA

Grant in 2020
BENANOVA develops safer antimicrobial products and eco-friendly materials for disinfectant, cosmetic, agricultural, and textile applications. Its Environmentally-benign Nanoparticles provide high efficacy with a degradable design, offering environmentally friendly replacements for silver nanoparticle antimicrobials and the potential to reduce chemical use in crop protection by up to 90%. The company also uses lignin-based, biodegradable materials from bio-renewable sources to support sustainable agriculture and specialty textiles, combining strong performance with reduced environmental impact.

Folia Water

Grant in 2020
Founded in 2016, Folia Water is dedicated to making clean drinking water accessible and affordable worldwide. The company specializes in manufacturing paper-based water filters infused with silver nanoparticles, reducing waterborne pathogens at a low cost. Their flagship product, Folia Filters™, is designed for affordability, targeting populations where access to clean water is limited due to financial constraints.

Valgotech

Grant in 2020
Founded in 2018, Valgotech is a technology company based in Fishers, Indiana. It specializes in advanced materials and energy storage systems, aiming to make energy consumption more sustainable and affordable.

SurgePower Materials

Grant in 2020
SurgePower Materials is a green technology company focused on producing high purity graphene, a specialized carbon-based nanomaterial, from renewable resources. The company employs a cost-effective and environmentally friendly manufacturing process to create its nanomaterials, which are designed to enhance the performance of advanced sustainable products, particularly in the realm of green energy storage technologies. SurgePower Materials aims to redefine the graphene market by positioning itself as a leader in the global graphene sector, supported by a dedicated team of inventors, business directors, project managers, and researchers.

CatalyzeH2O

Grant in 2019
CatalyzeH2O creates nanotechnology and electrochemical clean water solutions.

NanoPattern Technologies

Grant in 2019
NanoPattern Technologies develops photopatternable quantum dot formulations and nanoparticle inks for patterning high-resolution quantum dot downconverter layers, enabling displays for televisions, smartphones, wearables, augmented reality and virtual reality. Founded in 2019 and headquartered in Chicago, Illinois, the company’s direct nanoparticle lithography process is compatible with conventional photolithography and supports parallel patterning, helping manufacturers produce advanced display systems.

Silpara

Grant in 2019
Silpara Technologies specializes in developing molecular technology aimed at enhancing vehicle fuel economy. The company utilizes a combination of biotechnology and nanotechnology to create innovative composite materials that reduce friction in tires. By improving tire performance, Silpara's solutions enable the logistics industry to decrease fuel consumption and boost profitability. The company is committed to addressing customer inquiries through various channels, including phone, email, and online applications.

MITO Material Solutions

Grant in 2019
MITO Material Solutions is a specialty chemical company that develops and manufactures graphene-based hybrid polymer modifiers and nano-additives to improve the durability and performance of composite materials. Its product lines include hybridized graphene oxide and epoxide-based modifiers that strengthen fiber-reinforced thermoset and thermoplastic resins, and the E-GO material used in carbon fiber components. The company also markets the T-Series nano-additives, which toughen epoxy and resin systems to increase toughness and reduce material usage. These additives are used in resins and thermoplastics such as PA66 and find applications across aerospace, automotive, wind energy, and transportation sectors, including RVs and boats. MITO was founded in 2016 and is based in Indianapolis, with an additional office in Stillwater, Oklahoma.

Yesse Technologies

Grant in 2019
Yesse Technologies is a biotechnology company focused on developing an innovative genetic biosensing platform that digitizes the sense of smell. The company utilizes advanced nanotechnology and the biology of real noses to create a unique solution involving genetically modified super sniffer mice, which contribute to a live, human nose-on-a-chip. This technology aims to identify and catalog every conceivable odor, from fragrances used in perfumery to those linked with various diseases. By merging molecular biology, genetic manipulation, and olfaction, Yesse Technologies is positioned to transform odor detection and identification, providing valuable insights across various fields.

Core Quantum Technologies

Grant in 2019
Core Quantum Technologies develops probing nanoparticles for medical imaging, detection, and targeting. The company's micelle-encapsulated nanocrystals emit distinct colors to tag molecules in biomedical tests, enabling researchers to continuously track tagged molecules and gain unblinking, long-lasting insights into nanoscale activity.

Coreless Technologies

Grant in 2019
Coreless Technologies specializes in the design and manufacture of hollow metal nanoparticles aimed at improving the performance of nano-enabled devices. The company utilizes a continuous flow process to produce these nanoparticles, allowing for precise control over their size, shape, and optical properties. This technology is particularly beneficial for military applications in potentially contaminated areas, providing essential support in environments with limited healthcare access. Additionally, Coreless Technologies' innovations extend to agricultural sectors, where they facilitate the detection of plant-based diseases, thereby enhancing overall farming efficiency and safety.

Uniqarta

Grant in 2019
Uniqarta specializes in the development of advanced technologies for the manufacture of flexible electronics, focusing on small, ultra-thin integrated circuits (ICs). The company has developed a proprietary laser-enabled assembly technology that significantly enhances the efficiency of chip placement by replacing traditional pick-and-place methods with a fast, massively parallel approach. This innovative technology allows for the seamless integration of ultra-thin ICs into everyday materials such as paper and plastic, resulting in Smart Materials that eliminate the need for additional RFID labels. By addressing critical integration challenges, Uniqarta empowers electronics manufacturers to create next-generation products that contribute to the evolution of the Internet of Things (IoT).

Avisi Technologies

Grant in 2019
Avisi Technologies Inc. is a Philadelphia-based company founded in 2017 that specializes in developing innovative solutions for glaucoma treatment. Its primary product, VisiPlate, is a next-generation, nanotechnology-enabled aqueous shunt designed to prevent blindness caused by glaucoma. Through its advanced technology, Avisi Technologies aims to enhance the effectiveness of glaucoma management and improve patient outcomes.

BioHybrid Solutions

Grant in 2019
BioHybrid Solutions is a biotechnology company that specializes in developing advanced nanoarmored protein-polymer conjugates. The company focuses on tailoring the activity and stability of proteins and enzymes for various applications. Utilizing atom transfer radical polymerization chemistry, BioHybrid Solutions precisely grows polymers from the surface of proteins, enhancing their functionality. Through its research and development efforts, the company aims to provide innovative alternatives for therapeutics and protein engineering, ultimately contributing to advancements in medical treatments.

Labsys

Grant in 2019
Labsys is a company based in East Lansing, Michigan, founded in 2011, that specializes in the development of microelectronics and microfabrication technology. The firm focuses on creating solutions for government, industry, and academic partners, primarily aimed at enhancing safety and efficiency in various applications. Labsys's technology is designed to control sensors for detecting toxic or explosive gases and to facilitate quality control processes. Additionally, the company offers non-destructive evaluation techniques for assessing the structural integrity of aircraft, as well as microfluidic integration for bio-analysis. Their innovations also include bio-mimetic self-adhesives, enabling the aircraft industry to implement advanced sensors and algorithms for identifying cracks and corrosion in airframes.

3i Nanotech

Grant in 2019
Founded in 2018, 3i Nanotech develops point-of-care platform technology designed to track protein biomarkers in human samples. Its proprietary system enables early detection of cardiac biomarkers and infectious diseases, facilitating prehospital testing for medical professionals.

EWPanel

Grant in 2019
EWPanel is a manufacturer of innovative technology focused on generating electricity through motion. Founded in 2016 by Chunhua Yao and Xudong Wang, the company produces powerless, flexible sensor subfloor mats made from natural materials, utilizing nanotechnology to harness ambient mechanical energy. These solar panels are designed to charge low-power electronics, including RFID chips, temperature sensors, and LED lights. By enabling self-contained power generation, EWPanel’s products find applications in smart flooring and smart shipping packages, offering sustainable energy solutions for various industries.

Photon Spot

Grant in 2019
Photon Spot specializes in superconducting nanowire single-photon detectors, their applications, and sub-Kelvin cryogenic systems. The company was founded in 2019 and is based in Monrovia, California.

Multiscale Systems

Grant in 2019
Multiscale Systems produces industrial innovations through technical engineering services and a robust in-house R&D program. The company specializes in metamaterial composites and focuses on advanced manufacturing.

Advanced Silicon Group

Grant in 2019
Advanced Silicon Group is a nanotechnology company founded in 2015, focused on commercializing innovative silicon nanotechnology developed by its employees. The company specializes in measuring host cell proteins in biomanufacturing, utilizing its advanced technology to enhance various applications, including photovoltaics, lithium-ion batteries, microfluidics, and micro-electromechanical systems (MEMS). Advanced Silicon Group is also engaged in the development of next-generation biosensors, leveraging silicon to enable multiplexed measurements that allow for the simultaneous detection of multiple protein concentrations. This capability aids clients in improving performance and reducing costs by integrating silicon nanowire arrays into their products.

Waviks

Grant in 2019
Waviks develops custom nanoanalysis and nanofabrication tools. The company was founded by Dr. Tom Moore in 2013 and is based in Dallas, Texas.

Malachite Technologies

Grant in 2019
Malachite Technologies, founded in 2010 and headquartered in San Francisco, California, specializes in providing fully integrated equipment and process services aimed at assisting customers in transitioning material science innovations from laboratory settings to manufacturing environments. The company offers a comprehensive range of products and services, including the design and fabrication of ultra-high vacuum and atmospheric pressure chambers, physical and chemical vapor deposition coating systems, automated production systems, and thin film analysis. Through its tailored solutions, Malachite Technologies enables clients to obtain custom tools and process support efficiently, facilitating advancements in material science.

ZwitterCo

Grant in 2019
ZwitterCo specializes in advanced membrane solutions for the treatment of highly impaired wastewater, enabling the reuse and recycling of water resources in industrial applications. The company's innovative reverse osmosis and nanofiltration technologies address the challenges of treating historically unfilterable streams by preventing fouling caused by organic molecules. ZwitterCo's membranes are chlorine-tolerant, back-washable, and resistant to irreversible fouling, which enhances their longevity and performance. By transforming wastewater from a liability into a valuable resource, ZwitterCo helps clients manage their water treatment needs more economically and sustainably, reducing chemical demands and improving operational efficiency.

Metalmark Innovations

Grant in 2019
Metalmark Innovations, Inc. focuses on developing and delivering advanced 3D nanostructured coatings designed to treat airborne pollutants and toxins, enhancing indoor air quality. The company offers its innovative materials as additive coatings for various applications, including building materials and vehicle interiors, effectively addressing pollutants such as hydrocarbons, carbon monoxide, ozone, PM2.5, volatile organic compounds, odors, and germs. Its air cleaning technology employs catalytic materials that filter air with nanoscale precision, contributing to solutions for air pollution and climate change challenges. Founded in 2017 and headquartered in Boston, Massachusetts, Metalmark Innovations was previously known as Aircrew Technologies, Inc. before rebranding in January 2019.

Aligned Carbon

Grant in 2019
Aligned Carbon Inc. is a manufacturer of carbon nanotubes (CNTs) specifically designed for the integrated circuit industry. Established in 2018 and headquartered in Santa Clara, California, the company produces semiconductor-pure, aligned CNTs that are available on industry-standard wafers at a manufacturing scale. These CNTs are uniquely aligned in arrays that cover full semiconductor substrates and can be purified to be either entirely semiconducting or metallic. Aligned Carbon's technology facilitates a transition away from traditional silicon, allowing semiconductor foundries to achieve significant improvements in speed, energy efficiency, and performance in applications such as logic processing, signal processing, and advanced sensing technologies. The company's innovations enable clients to enhance computing applications through the integration of carbon nanotube logic with conventional silicon logic and memory, thereby addressing growing demands in the semiconductor sector.

Serinus Labs

Grant in 2019
Serinus Labs, Inc. is a manufacturer of nano-scale silicon gas sensors, established in 2017 and based in Berkeley, California. The company specializes in developing integrated chip-scale gas sensors tailored for various industries, including health and safety, automotive, consumer electronics, and healthcare. Serinus Labs offers custom solutions that address both existing and emerging market needs. In particular, the company focuses on providing ultra-low-power trace gas sensors for Li-ion battery state-of-health monitoring, which enhances battery intelligence in electric vehicles. Through its innovative technology, Serinus Labs aims to meet critical demands across strategic markets.

COnovate

Grant in 2019
COnovate is a company developing advanced lithium-ion battery components. It uses graphene monoxide to enhance energy storage capacity in batteries.

Guardion

Grant in 2019
Guardion is a technology company specializing in advanced sensor technology, particularly in the development of radiation detectors that utilize the quantum properties of nanomaterials. This innovative approach allows Guardion to create low-cost, highly sensitive, and energy-efficient detectors suitable for large-scale deployment, especially in urban environments. The company focuses on applications that demand high sensitivity and miniaturization, providing analytical instruments and chemical detectors that serve various industries, including aerospace, healthcare, and national security. Guardion has received recognition for its contributions to the field, winning multiple awards such as the MassChallenge Gold Prize and the Technology in Space Prize from CASIS and Boeing. Additionally, the company participated in the inaugural cohort of the Techstars Autonomous Tech Accelerator, which is sponsored by the Air Force.

ZeoVation

Grant in 2019
Founded in 2016, ZeoVation specializes in manufacturing nanozeolites and hierarchical zeolites. These materials enhance consumer products such as skincare lotions, sunscreens, laundry detergents, water softeners, and filtration systems by improving efficiency.

Scion Plasma

Grant in 2019
Scion Plasma is a technology company that develops plasma modeling software to overcome the limitations of ion sources in material processing. Founded in 2018 and based in East Lansing, Michigan, the company focuses on single-beam advanced plasma sources using sophisticated algorithms to assist the sputtering deposition of dense, smooth thin films, offering a potential drop-in replacement for existing vacuum systems at a lower cost.

SurfaSense

Grant in 2019
SurfaSense provides research and development in nanotechnology, biotechnology, physical engineering, and life sciences. They provide technologies for autonomous robotics.
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