National Science Foundation

Novaurum Biosciences develops AuPEC, a proprietary cell-based encapsulation technology for implanted orthopedic devices. This innovative approach combines microbiology and nanotechnology to create nano-biological coatings that significantly reduce infection rates and promote healing.

Dynocardia is a biomedical device company developing wearable, non-invasive blood pressure monitoring technology. Its ViTrack wrist-wearable device provides direct, beat-by-beat measurement of blood pressure and tracks heart rate, respiration, and rhythm with accuracy comparable to intra-arterial lines. The platform uses a wearable optomechanical sensor to enable continuous, mobile monitoring of cardiovascular parameters. Founded in 2018, the company is headquartered in Massachusetts and focuses on meeting critical clinical needs with portable monitoring solutions.

Amplified Sciences is a molecular diagnostics company developing a point-of-care platform that enables early detection of debilitating diseases. Its sensor-based and optical reporter systems, combined with machine learning and multi-analyte assays, target cancers and chronic conditions such as pancreatic cancer and kidney disease. The technology supports detection of low-abundance disease markers in urine and saliva, with scalability to cost-effective point-of-care formats. The company leverages ultra-sensitive sensing and composition-of-matter intellectual property licensed from Purdue University to deliver single-molecule level detection. Its portfolio aims to improve patient outcomes by enabling rapid, minimally invasive testing, reducing unnecessary procedures, and expediting diagnosis across oncology and other disease areas. The platform has demonstrated prototype data and is positioned for broad applicability across multiple disease states.

Theromics Inc., founded in 2016, develops innovative cell therapies. It specializes in HeatSYNC Gel, a biopolymer thermal accelerant that enhances microwave and radiofrequency energy absorption during soft tissue ablation procedures. This gel amplifies heat movement, optimizes ablation zone shape, increases treatment area, and protects critical tissues.

Astria Biosciences, based in Pittsburgh, specializes in developing innovative diagnostic and therapeutic solutions for cerebrovascular diseases. The company focuses on addressing neurosurgical challenges through molecular biology, advanced analytics, and small-molecule inhibitors, aiming to provide non-surgical alternatives for neurovascular conditions where surgery is currently the primary option.

CenSyn develops a portable brain health assessment platform. It comprises a handheld EEG device for rapid neurological evaluation, a mobile app for real-time data viewing, and machine learning algorithms to detect mental status changes. This enables medical professionals to conduct cognitive assessments across various settings.

Lapovations is a healthcare company founded in 2016 and headquartered in Fayetteville, Arkansas. It specializes in the development and manufacturing of innovative medical devices specifically designed for laparoscopic surgery. The company aims to redefine laparoscopy by creating products that minimize invasiveness, simplify surgical procedures, and enhance patient outcomes. By focusing on improving the safety and efficacy of surgical practices, Lapovations supports medical professionals in delivering high-quality care.

Eyebot develops innovative eye examination technology designed to eliminate barriers and enhance accessibility to vision care. Their flagship product is a freestanding, self-serve vision testing terminal that provides accurate eye prescriptions directly at the point of sale, enabling ophthalmologists to proactively improve eye care quality and reduce costs.

Alerje, Inc. is a Detroit-based company focused on enhancing the quality of life for individuals with food allergies. Founded in 2015, Alerje has developed an innovative emergency medicine and digital oral immunotherapy management platform. Central to its offerings is an epinephrine auto-injector that conveniently fits into a smartphone case, promoting better adherence and alert management for users. The company also provides a mobile application that allows users to create personalized food allergy profiles, share these profiles with caregivers and medical professionals, and filter recipes based on allergen information. Additionally, the app includes features for scanning grocery items to identify potential allergens, thus aiding families and healthcare providers in making informed dietary choices. Alerje's platform is validated by the National Science Foundation and aims to improve emergency response and overall management of food allergies.

Mente develops a surgical instrument tracking and monitoring system that uses predictive analytics to optimize the operating room experience for hospitals, surgical teams, and patients at the lowest possible cost. The solution provides dependable, real-time data streams on instrument availability and usage, helping to transform resource management in the OR. By ensuring the right instruments are on hand when needed, Mente aims to improve efficiency, reduce downtime, and lower overall surgical costs while supporting better patient care.

Avisi Technologies Inc. is a Philadelphia-based company founded in 2017 that specializes in developing innovative solutions for glaucoma treatment. Its primary product, VisiPlate, is a next-generation, nanotechnology-enabled aqueous shunt designed to prevent blindness caused by glaucoma. Through its advanced technology, Avisi Technologies aims to enhance the effectiveness of glaucoma management and improve patient outcomes.

Emagine Solutions Technology, LLC is a Tucson, Arizona-based company specializing in mobile ultrasound imaging technology. Its flagship product, VistaScan, converts standard mobile devices into advanced ultrasound imaging tools, enhancing diagnostic capabilities in medical settings. The company is developing its innovative technology at the Arizona Center for Innovation, a business incubator located within the UA Tech Park, where it benefits from various business assistance programs and facilities designed to support emerging technology firms. Emagine Solutions Technology aims to improve healthcare delivery through its cutting-edge solutions.

Samay specializes in remote respiratory health management. It develops AI-enabled wearable devices that monitor pulmonary volumes, trapped air, heart rates, breathing sounds, and lung temperature. This enables users to analyze their respiratory data and helps prevent respiratory diseases.

Quantivly, Inc., established in 2019 and headquartered in Somerville, Massachusetts, specializes in developing artificial intelligence-based solutions tailored for the field of radiology. The company focuses on enhancing data liquidity and providing analytical tools that enable radiology providers to make informed decisions, thereby increasing access to medical imaging services. Quantivly's platform is designed to manage and analyze MRI imaging workflows by cleaning and harmonizing scanner data, resulting in a vendor-neutral and comprehensive source of operational knowledge. This innovative approach supports radiology departments and imaging centers in utilizing data analytics to improve decision-making, facilitate new research initiatives, and enhance the overall patient experience in healthcare.

Infusense develops a biosensor platform that employs electrochemistry for precise quantification of lipophilic drugs. This technology enables rapid, sensitive sample analysis, allowing healthcare providers and researchers to perform drug detection and analysis with laboratory-grade accuracy in a portable format.

EYSZ is a digital health software company based in Piedmont, California, founded in 2018. It specializes in detection algorithms that utilize oculometric and facial biometric data to reliably detect seizures and assist in the diagnosis and management of brain disorders, including epilepsy, ADHD, and depression. By employing machine learning techniques, EYSZ's software not only detects seizures but also predicts their occurrence. The platform is designed to interface and integrate with various eye-tracking systems, such as smart glasses, and therapeutic devices like neuromodulation tools, thereby enhancing the ability of clinicians to monitor and manage the neurological health of their patients effectively.

NeuroGeneces develops an artificial intelligence driven brain health assessment platform to detect early signs of neurodegeneration before cognitive symptoms appear. Its Brain Age test analyzes patient EEG data collected via a sleep headband and ML software, benchmarking against a proprietary normative database to provide objective measures of brain function. The platform enables healthcare practitioners to identify at-risk individuals and guide preventive interventions through early behavioral strategies, offering more comprehensive insights than traditional biomarkers.

MALCOVA develops medical imaging devices focused on early detection and diagnosis of breast cancer in women with dense breasts. It leverages proprietary Narrow-Beam Computed Tomography technology and AI-based software to deliver safe, rapid, high-quality imaging.

ProMedix is a medical device startup based in Portland, Oregon, founded in 2019. The company specializes in the development of noninvasive, fingertip patient monitors aimed at enhancing the recognition of circulatory dysfunction. Its innovative devices are designed to assist in the diagnostic evaluation and monitoring of various medical conditions, such as trauma, dehydration, and sepsis. By facilitating effective home patient monitoring, ProMedix aims to simplify both home and critical care, helping physicians to prevent unnecessary acute visits and improve overall emergency and critical care outcomes.

ReSuture, founded in 2019, specializes in high-fidelity physical simulations for surgical training, particularly in open vascular procedures. The company develops innovative surgical instruments that address challenges in contemporary medical simulation. These instruments provide physical stimulation, allowing users to acquire vascular surgical skills in a controlled environment. By enabling medical practitioners to replicate the mechanical properties of human vascular tissue, ReSuture enhances the training experience for future surgeons. This approach not only improves psychomotor skills but also reduces training time, ultimately aiming to enhance patient outcomes and minimize surgical complications.

BLOCKsyncop is a company focused on developing innovative clinical monitoring devices aimed at enhancing anesthesiology practices. Its primary product is a non-invasive, real-time tool designed to objectively measure and quantify the effectiveness of neural blocks for pain management. This technology assists anesthesiologists in reducing the occurrence of failed neural blocks, minimizing anesthetic toxicity, and optimizing the analgesic requirements for patients. By providing precise data, BLOCKsyncop aims to improve patient outcomes in pain management and support healthcare professionals in delivering safer and more effective anesthesia care.

PneumoNIX Medical is focused on creating innovative gel-based technologies aimed at minimizing complications that can arise from percutaneous procedures, particularly soft tissue biopsies. The company's primary objective is to address and reduce the risk of collapsed lung complications during CT-guided lung biopsies. By developing these specialized medical devices, PneumoNIX Medical seeks to enhance patient safety and improve outcomes in interventional procedures.

Vivifi Medical develops a laparoscopic device that enables quick connection of two blood vessels. Headquartered in Houston, Texas.

Moshion is a technology company specializing in healthcare workflow optimization, specifically targeting the nursing shortage. It employs 3D image sensors, preserving patient privacy, to gather movement data, which is then analyzed using machine learning models. Moshion's primary focus is to prevent pressure injuries in bedridden patients by monitoring and optimizing patient turning protocols. The platform tracks adherence to these protocols, provides personalized turn schedules, sends reminders to nurses, and automates documentation. This data-driven approach aims to enhance patient care, improve nursing efficiency, and reduce the risk of life-threatening events.

Sharper Sense develops wearable neurotechnology to enhance vision, hearing, and touch. The company focuses on a neuromodulation patch that delivers non-invasive electrical stimulation to improve sensory acuity and perception, with potential applications for processing disorders and sensory loss, and to boost performance, enabling clearer, more accurate perceptions for improved task precision and safety.

OmniVis is a biotechnology company specializing in pathogen detection. It offers an integrated portable platform that rapidly and accurately identifies pathogens in various environments, reducing the need for labor-intensive lab testing.

CoraVie Medical is an early-stage medical device startup focused on improving blood pressure monitoring for patients with uncontrolled hypertension. Their innovative gadget will be the first to provide actionable insights, enabling timely interventions and cost-effective therapies to prevent organ damage.

CPR Therapeutics is a medical device company focused on developing an advanced automated cardiopulmonary resuscitation (CPR) system. The company's innovative technology integrates multiple technological advancements into a single system designed for easy application under emergency conditions. This multimodal CPR system enhances blood flow and the efficacy of electrical countershock, capabilities that are beyond human performance. By combining chest compressions with artificial ventilation, the system aims to preserve brain function and restore spontaneous circulation and breathing in cardiac arrest patients, thereby improving survival rates significantly.

BioSuperior Technology is a preclinical biotherapeutics company specializing in lung disease treatments. It has developed a novel, synthetic pulmonary surfactant prototype called BioSurf, which mimics the body's natural surfactant to facilitate breathing and deliver therapeutic drugs. This non-invasive, cost-effective technology aims to restore normal lung function and repair damaged lung tissue. Additionally, BioSuperior's platform has potential applications in treating other microvasculature-related illnesses, such as hemorrhagic stroke and chronic kidney disease.

Senseer Health, founded in 2017, focuses on addressing the chronic disease market by developing Smart Medical Device Therapies for managing various chronic conditions, which affect a significant portion of older adults. The company's innovations began with patented microsensors that monitor implantable devices for patients with hydrocephalus, renal, and cardiovascular diseases. To enhance the effectiveness of these microsensor-enabled devices, Senseer has incorporated advanced wearable and ambient sensor technologies. The integration of these multi-modal sensor technologies with an IoT software platform allows for the utilization of proprietary data sets and predictive analytics. This comprehensive approach provides healthcare providers with tools for remote monitoring and timely interventions, ultimately aiming to improve the quality of life for individuals with chronic conditions while reducing costs and enhancing patient safety.

Scopi Medical is a mission-driven company focused on advancing medical optical imaging technology for clinics. By developing a sophisticated hardware platform complemented by state-of-the-art artificial intelligence and machine learning software, Scopi Medical aims to enhance the accuracy of point-of-care diagnostics. Their innovative imaging devices enable practitioners to diagnose and monitor chronic nasal conditions, such as rhinosinusitis, with greater precision and at an earlier stage than traditional methods allow. Additionally, their technology facilitates remote collaboration between healthcare providers and specialists, ensuring that areas of concern can be visualized and treated effectively, ultimately improving patient outcomes.

CardioPhi is an artificial intelligence company developing tools for automatic and reliable interpretation of electrocardiograms to assist clinicians in diagnosing and managing cardiac arrhythmias. By applying AI to heart function data, CardioPhi aims to improve patient outcomes and reduce public spending on cardiovascular diseases through faster, more accurate ECG analysis and clinical decision support.

Claria Medical specializes in developing innovative, minimally invasive surgical tools aimed at enhancing women's healthcare procedures. Their primary focus is improving hysterectomy and myomectomy surgeries by reducing tissue spread risk during laparoscopic procedures. Claria has received notable recognitions such as the 'Safer Technologies Designation' from the FDA and grants from the National Science Foundation and National Institute of Health.

Evolution Devices is a neuro rehabilitation technology company that creates functional electrical stimulation devices. Its flagship product, EvoWalk, uses artificial intelligence to track walking patterns and personalize therapy for individuals recovering from neurological impairments such as stroke or multiple sclerosis.

NeuroGeneces develops an artificial intelligence driven brain health assessment platform to detect early signs of neurodegeneration before cognitive symptoms appear. Its Brain Age test analyzes patient EEG data collected via a sleep headband and ML software, benchmarking against a proprietary normative database to provide objective measures of brain function. The platform enables healthcare practitioners to identify at-risk individuals and guide preventive interventions through early behavioral strategies, offering more comprehensive insights than traditional biomarkers.

CoLabs Inc. is a medical device manufacturing company founded in 2012 and headquartered in Morgan Hill, California. The company specializes in developing Ventor, an innovative emergency airway and ventilation system aimed at improving airway management and ventilation during cardiac arrest. CoLabs' device offers medical professionals a new approach to effectively manage airway access and ventilation, enhancing the response to patients experiencing cardiac emergencies.

Brio provides strategic resourcing solutions to the biopharma, pharmaceutical, CRO, and medical device industries. They are skilled search experts with a passion for the science and art of recruiting, introducing only the best talent to preeminent companies.

Samay specializes in remote respiratory health management. It develops AI-enabled wearable devices that monitor pulmonary volumes, trapped air, heart rates, breathing sounds, and lung temperature. This enables users to analyze their respiratory data and helps prevent respiratory diseases.

Founded in 2018 and based in Baltimore, Maryland, Relavo develops a medical device aimed at preventing infection in peritoneal dialysis. Its flagship product, PeritoneX, is an inline connection device designed to disinfect dialysis tubes at all system connection points, making home dialysis safer and more accessible for kidney failure patients.

Rush River Research offers mechanical and electrical design, epidemiology, and medical device project management to take ideas from concept to product. They use state-of-the-art electronics and materials. They partner with medical device companies, physicians, and academics who are also committed to improving healthcare devices.

AirOmatix is a biotechnology company focused on innovating methods for oxygen concentration, storage, and delivery across various sectors, including healthcare, athletics, and food storage. The company is commercializing a novel, patent-pending technology that utilizes photochemical reactions to concentrate and remove oxygen from ambient air. This process achieves higher purity levels above 99% and greater flow rates compared to traditional pressure swing adsorption devices. AirOmatix is developing high-flow oxygen concentrators that can produce continuous flow rates exceeding 6.0 L/min, while also creating ultra-portable devices that are comparable in size to a coffee mug. For industrial applications, the technology aims to replace the need for truckload deliveries of liquid oxygen by providing on-site generators capable of producing multiple tons of high-purity liquid oxygen daily.

AmCyt is a company focused on enhancing pathological analysis through the development of a rapid onsite diagnostic device. This innovative technology streamlines the biopsy process by allowing for the smearing of tissue samples onto glass slides, followed by staining and real-time microscopic evaluation. By improving the efficacy of biopsies, AmCyt addresses labor shortages in clinics and hospitals, ultimately leading to better patient outcomes. The company's solutions aim to reduce the need for additional sampling and minimize the risk of complications associated with procedures, thereby saving time, money, and resources for healthcare providers.

AccuBreath specializes in developing innovative respiratory care solutions. Their flagship product is an affordable, high-end, ultraportable ventilator designed for gentle and portable respiratory support during medical procedures.

Strados Labs, LLC is a medical technology company based in Philadelphia, Pennsylvania, specializing in respiratory health management through innovative sensor-based solutions. Founded in 2016, the company has developed a wearable device that provides real-time insights into breathing patterns, sounds, and speed. This device is equipped with clinical-grade biosensors and smart software, allowing for continuous monitoring of respiratory conditions such as asthma and chronic obstructive pulmonary disease. By connecting to a mobile application, Strados enables users and healthcare providers to access and analyze respiratory data, facilitating informed health decisions and remote patient monitoring.

Ai-Ris offers automated retinal examinations for primary care. Their retinal imaging system allows general practitioners to screen for diabetic retinopathy without the presence of a specialist. This system consists of a portable headset that uses machine learning algorithms to classify images of the retina of patients without dilating their pupils.

NeuRx Medical specializes in developing percutaneous thrombectomy technologies designed to treat ischemic stroke and other vascular conditions. Their innovative devices enable endovascular specialists to rapidly stabilize, retain, and retrieve blood clots during image-guided thrombectomy procedures, aiming to improve patient outcomes.

Hypersound Medical is focused on developing non-invasive neuromodulatory devices that utilize neurostimulation techniques to address chronic pain conditions. The company's products employ microwave energy to stimulate nerve cells, offering pain relief for various ailments, including arthritis, back pain, and neuropathic pain. By enhancing pain management, Hypersound Medical aims to improve patient function and reduce reliance on pain medication. Their approach encompasses various stimulation methods, such as peripheral nerve stimulation and spinal cord stimulation, positioning the company as a key player in the field of pain relief technology.

Lura Health develops a non-invasive continuous health monitoring platform that uses saliva as a diagnostic fluid. The company integrates micro-sensors into orthodontic devices such as retainers, aligners, and brackets to continuously measure saliva analytes and securely transmit data to a smartphone app, enabling users to monitor oral health metrics and potentially support broader chronic disease management. Target markets include heart disease, chronic kidney disease, diabetes, and tooth decay. Founded in 2017, the company is based in Cambridge, Massachusetts.

Renerva is a rapidly-growing medical device company focused on developing and commercializing implantable technologies to enhance the outcomes of peripheral nerve repair procedures. The company specializes in creating surgical devices designed to facilitate nerve recovery and improve functionality post-injury, aiming to accelerate healing and restore patient mobility.

Our mission is to promote innovation that empowers people to have the knowledge and tools to solve everyday medical problems in any setting. We do this by providing a doctor’s approach to stopping nosebleeds at your fingertips. Bleed Freeze allows people to confidently take control and treat nosebleeds anywhere.

GeniPhys develops and commercializes standardized tunable collagen polymers and collagen-fibril materials for research and medical applications. It manufactures research-grade collymers and polymerization reagents that enable customization of 3D collagen-fibril matrices for in-vitro tissue systems used in drug discovery, toxicity testing, and basic cell and tissue research, as well as engineered tissue and organ constructs and 3D bioprinting. The product line includes oligomer polymerization kits, polymerization buffers, supplements, and related reagents, which are sold online. Founded in 2014 and based in Zionsville, Indiana, the company focuses on designing collagen materials for site-appropriate tissue generation and potential delivery of pharmaceutical and cell-based therapies.

Juggernaut Life Sciences specializes in developing innovative medical technologies. They focus on four key areas: medicine, image guidance, robotics, and artificial intelligence. Their primary business is designing and developing medical devices and platforms that can perform routine procedures with minimal human intervention, aiming to enhance safety and reduce costs for their clients.

Dynocardia is a biomedical device company developing wearable, non-invasive blood pressure monitoring technology. Its ViTrack wrist-wearable device provides direct, beat-by-beat measurement of blood pressure and tracks heart rate, respiration, and rhythm with accuracy comparable to intra-arterial lines. The platform uses a wearable optomechanical sensor to enable continuous, mobile monitoring of cardiovascular parameters. Founded in 2018, the company is headquartered in Massachusetts and focuses on meeting critical clinical needs with portable monitoring solutions.

SafeBVM develops a medical device accessory designed to prevent hyperventilation during manual resuscitation. Its product, Sotair, uses a flow-blocking valve mechanism to regulate airflow and reduce complications such as stomach insufflation and respiratory distress.

Isolere Bio, established in 2018, is a healthcare company specializing in biotherapeutic purification. Its core business involves simplifying and optimizing the manufacturing process of monoclonal antibodies and Adeno-Associated Viruses (AAVs) using Tangential Flow Filtration (TFF) technology. This streamlined approach aims to enhance global access to these vital drugs and research tools, while facilitating a seamless transition from laboratory-scale production to industrial-level output.

Founded in 2018, Aurie is a medical device company specializing in reusable urinary catheterization systems. Its flagship product is a portable, battery-operated case that washes, dries, and stores catheters, enabling individuals with mobility or neurological conditions to perform safe and independent urinary care.

Auctus Biologics is a pre-clinical biotechnology company that develops antibody mimetic scaffolds for therapeutic and diagnostic applications. The company is engineering a ribose-binding protein to bind clinical targets with an affinity comparable to monoclonal antibodies while offering enhanced stability that allows survival in extreme environments, including repeated boiling cycles. This approach aims to address antibodies' liabilities, such as instability and costly cold-chain requirements, in order to enable advanced treatments and reduce overall treatment costs.

Reselute specializes in designing, developing, and validating innovative medical devices. Their primary focus is on creating orthopaedic spacers that enhance the treatment of implant-related infections, enabling healthcare professionals to accelerate recovery and improve patient care.

Pathotrak specializes in rapid food safety testing. Its patented technology reduces detection time of pathogens like Salmonella and E. coli from days to hours, meeting FDA and USDA regulations. This innovation helps minimize holding costs, enables swift recalls, and enhances overall food safety.

Psyonic, Inc. is a company that develops advanced bionic limbs aimed at enhancing the lives of individuals with amputations. Founded in 2015 and headquartered in Champaign, Illinois, Psyonic focuses on creating innovative prosthetic solutions, with its flagship product being an advanced bionic hand. This hand features muscle pattern recognition technology and provides sensory feedback, allowing users to perform everyday tasks with greater ease. Designed to be user-friendly and durable, it is also positioned to be affordable, with aspirations for full insurance coverage to eliminate out-of-pocket costs for users. The company's commitment to accessibility ensures that its products cater to a wide range of needs for those with amputations and injured limbs.

OsciFlex LLC, established in 2017 and headquartered in Philadelphia, Pennsylvania, specializes in developing a medical device aimed at preventing blood clots from forming at valves. The company's innovative product mimics nature's process to provide more effective compression therapy, reducing the risk of Venous thromboembolism (VTE) in patients and potentially decreasing reliance on costly and risky anti-coagulation pharmaceuticals.

Monogram Orthopaedics is a medical equipment manufacturing company. Monogram Orthopaedics develops a solution architecture for enabling the mass personalization of orthopaedic implants by linking 3D printing and robotics via automated digital image analysis algorithms. They offer a delivery solution for patient-specific load-bearing joint replacements. Monogram Orthopaedics is paving the way for the future of joint replacement surgery.

CereVu Medical specializes in developing advanced medical devices. Their primary product is a wearable, single-use forehead patch connected to a reusable console, designed to monitor and analyze cerebral hemodynamics in real-time. This system employs proprietary algorithms to provide continuous pain score assessments, enabling healthcare professionals to tailor treatments based on individual patient needs.

BiRed Imaging specializes in advanced medical imaging technology focused on the early detection of breast cancer. The company has developed an innovative platform that combines infrared imaging with a proprietary computerized detection algorithm, enabling accurate identification of the size and location of tumors, particularly in patients with dense breast tissue. This technology serves as an effective adjunct to traditional breast cancer screening methods, helping clinicians to recognize high-risk patients at an early stage. By enhancing the accuracy and cost-effectiveness of breast cancer detection, BiRed Imaging aims to improve patient outcomes in oncology.

IntuiTap Medical is a medical device company that develops a handheld system to guide spinal puncture procedures. The device aims to eliminate guesswork, frustration, and pain associated with spinal taps by integrating spine imaging, needle guidance, and analytics to enable accurate needle placements for lumbar punctures, spinal anesthesia, and epidurals. The system seeks to improve procedure efficiency and reduce costs while enhancing clinician confidence and patient experience. The company was founded in 2016 and is headquartered in Houston, Texas.

Huxley Medical is a private company focused on developing medical devices. It collaborates with leading clinicians and scientists to create innovative devices and algorithms, enhancing users' access to diverse diagnostic tools and treatment options.

MBF Therapeutics, Inc. is a veterinary oncology company based in Ambler, Pennsylvania, focused on developing and commercializing innovative therapies for cancer treatment in dogs and cats. The company specializes in targeted immunotherapies and small molecule drugs that effectively disrupt tumor cell metabolism while preserving healthy cells and organs. Its product portfolio includes MBFT-101, a combination therapy for sarcomas and lymphoma, featuring a proprietary polyamine transport inhibitor and a potent inhibitor of ornithine decarboxylase, as well as MBFT-102, an immunotherapy based on the tumor suppressor/cytokine mda-7/IL24, which has shown promise in human cancers. Additionally, MBF Therapeutics employs a proprietary DNA vaccine platform and delivery system to develop immunotherapeutic vaccines aimed at enhancing protective immunity against infectious diseases in companion animals and livestock. The company maintains a strategic partnership with the Lankenau Institute for Medical Research to further advance its research and development initiatives.

Coreless Technologies specializes in the design and manufacture of hollow metal nanoparticles aimed at improving the performance of nano-enabled devices. The company utilizes a continuous flow process to produce these nanoparticles, allowing for precise control over their size, shape, and optical properties. This technology is particularly beneficial for military applications in potentially contaminated areas, providing essential support in environments with limited healthcare access. Additionally, Coreless Technologies' innovations extend to agricultural sectors, where they facilitate the detection of plant-based diseases, thereby enhancing overall farming efficiency and safety.

Atom Limbs is focused on advancing the field of prosthetics with its innovative mind-controlled artificial arms, specifically designed for under-elbow amputees and individuals with quadriplegia. The company’s flagship product, the Atom Touch, allows users to regain mobility by interpreting brain signals through implanted electrodes, facilitating natural and intuitive movement of the prosthetic limb. This technology is rooted in research and development conducted at the Johns Hopkins University Applied Physics Laboratory and has received substantial funding from DARPA. Atom Limbs aims to enhance the quality of life for those with mobility challenges by providing advanced, customizable solutions for artificial limbs.

EYSZ is a digital health software company based in Piedmont, California, founded in 2018. It specializes in detection algorithms that utilize oculometric and facial biometric data to reliably detect seizures and assist in the diagnosis and management of brain disorders, including epilepsy, ADHD, and depression. By employing machine learning techniques, EYSZ's software not only detects seizures but also predicts their occurrence. The platform is designed to interface and integrate with various eye-tracking systems, such as smart glasses, and therapeutic devices like neuromodulation tools, thereby enhancing the ability of clinicians to monitor and manage the neurological health of their patients effectively.

Quadralynx develops wearable biometric devices designed to assist adults with motor speech disorders, particularly those experiencing volume control issues stemming from Parkinson’s disease or related neurological conditions. The device alerts users via vibration when they exhibit pathological voice states.

CorInnova Incorporated, founded in 2004 and based in Houston, Texas, specializes in device-based therapies aimed at treating congestive heart failure. The company is known for its innovative non-blood-contacting soft robotic cardiac assist device, which has the potential to significantly increase the number of heart failure patients eligible for life-saving device therapies. By focusing on advanced technological solutions, CorInnova seeks to improve outcomes for individuals suffering from this serious condition.

Averto Medical specializes in the manufacture of medical devices designed to improve outcomes for patients with gastrointestinal diseases. Their innovative solutions aim to facilitate minimally invasive colorectal tumor removal and other gastrointestinal surgeries, enabling healthcare professionals to provide optimal care.

Nasus Medical specializes in developing innovative, non-invasive drug-delivery devices aimed at improving the treatment of chronic sinusitis. Their flagship product enables patients to self-administer medication rapidly and conveniently, reducing the need for oral medications with systemic side effects, injections by healthcare professionals, or costly surgical procedures. This approach aims to enhance patient comfort, convenience, and outcomes while lowering overall healthcare costs.

Cision Vision is a biotechnology company focused on developing and supplying innovative imaging medical products specifically designed for the examination of lymph nodes. Its advanced imaging devices enable pathologists to visualize, scan, and record lymph nodes in real-time with high contrast, eliminating the need for injections or radiation. By providing pathologists with tools that enhance the accuracy and consistency of pathology grossing, Cision Vision aims to modernize the field and improve the quality of care delivered to patients.

BioSapien is a biotechnology company developing innovative, biodegradable implantable devices that deliver pharmaceuticals directly to cancer sites. Its flagship product, MediChip, uses 3D printing technology to create a mesh capable of sustained drug release, reducing systemic side effects and improving patient care.

Aspero Medical, Inc. is a medical device manufacturer based in Boulder, Colorado, founded in 2018. The company specializes in gastrointestinal balloon endoscopy, focusing on improving both the patient experience and procedural efficiency for physicians. Its flagship product, the AP Balloon Overtube, incorporates innovative pillar technology that enhances device performance by maximizing frictional properties. This design increases mucosal wall traction and anchoring consistency within the gastrointestinal tract, ultimately allowing for reduced procedure times and sedation needs. By emphasizing improvements in patient outcomes and cost-effectiveness, Aspero Medical aims to advance the field of gastrointestinal diagnostics and treatment.

Eyebot develops innovative eye examination technology designed to eliminate barriers and enhance accessibility to vision care. Their flagship product is a freestanding, self-serve vision testing terminal that provides accurate eye prescriptions directly at the point of sale, enabling ophthalmologists to proactively improve eye care quality and reduce costs.

ColoWrap, LLC is a medical device company based in Durham, North Carolina, established in 2012. The company specializes in developing a non-invasive device designed to enhance the efficiency and comfort of colonoscopy procedures. ColoWrap's innovative device exerts sustained, adjustable pressure on the patient's lower abdomen, effectively preventing looping in the colon. This minimizes the need for manual pressure and reduces the necessity for patient repositioning during the procedure. Constructed from latex-free material similar to that used in high-performance wetsuits, the device aims to facilitate a more comfortable and less invasive experience for patients while allowing medical practitioners to perform colonoscopies more effectively.

Envivo Bio develops a non-invasive device that collects microbiome samples from all regions of the human gastrointestinal tract. The company is based in San Carlos, California.

Precision Neuroscopics is a medical device company headquartered in Pittsburgh, Pennsylvania, specializing in the development of advanced high-density electroencephalography (EEG) systems. The company focuses on creating innovative technologies that enable the non-invasive detection of brain signals, particularly those indicative of worsening traumatic brain injury. By engineering high-density and user-friendly brain recording systems, Precision Neuroscopics aims to enhance the quality of EEG signal recording while reducing clinical time and costs for healthcare providers.

Green Sun Medical, LLC is a medical device company specializing in the design, development, and manufacturing of orthotic braces for the treatment of Adolescent Idiopathic Scoliosis (AIS) and Kyphosis. Founded in 2013 and based in Fort Collins, Colorado, the company is focused on creating innovative solutions to correct spinal deformities. Its flagship product is a dynamic spinal alignment brace that applies continuous corrective pressure to the spine, facilitating effective treatment for conditions such as scoliosis and kyphosis. This technology-enabled brace not only aids in the physical correction of spinal issues but also allows physicians to remotely monitor its performance in real-time, enhancing patient care and recovery outcomes.

CollaMedix is a company focused on the development of innovative medical devices for soft tissue repair and augmentation, particularly addressing stress urinary incontinence in women. Utilizing proprietary collagen-based materials, CollaMedix offers a bio-inductive scaffold made from pure collagen that provides structural support to human tissue. This advanced collagen fabric is designed to withstand significant loads while promoting rapid cell integration. By facilitating the development of new treatments for female pelvic health, CollaMedix aims to deliver safe and effective solutions for conditions related to urine leakage that occur during activities such as laughing, coughing, sneezing, lifting, and exercise.

xMD Diagnostics, based in Annapolis, Maryland, specializes in the biotechnology sector, focusing on molecular diagnostics tools that enhance research and clinical laboratory practices. Formerly known as Bay Resources Development Group, the company employs advanced high-throughput microdissection technology to aid in cancer diagnosis. Its innovative tools enable the isolation and enrichment of specific cells from biopsy and other specimen samples, facilitating downstream applications such as polymerase chain reaction (PCR), genomic and proteomic analyses, next-generation sequencing (NGS), and various molecular testing methods. This technology supports pathologists, oncologists, and other medical professionals in diagnosing, monitoring, and treating patients with cancer and serious genetic diseases.

Niche Biomedical is a platform and therapy development firm that specializes in innovative treatments for chronic injuries and disorders that have not responded to conventional pharmacological methods. The company has developed the ExaStim, a non-invasive neuromodulation system designated as an FDA Breakthrough Device, aimed at treating spinal cord injuries. Additionally, Niche Biomedical is working on a gastrointestinal therapeutic device designed to alleviate postoperative ileus and restore gastrointestinal motility. This device leverages bioelectronic medicine to address diseases and injuries that are resistant to pharmaceutical therapies. The firm is also capable of creating miniaturized implantable devices with advanced functionalities, allowing for diverse electrode configurations to enhance treatment options through neuromodulation.

Synopic develops advanced imaging technology for minimally invasive medical procedures. Utilizing a single camera implementation, they capture measurable 3D information and high-resolution color images, enhancing visualization and decision-making during surgeries.

SpineX develops and tests neuromodulation technologies for non-invasive devices that aid recovery in individuals with neurological conditions such as strokes, spinal cord injuries, multiple sclerosis, and cerebral palsy. Their focus is on restoring bladder, bowel, respiration, sexual, and sensorimotor functions.

Zeteo Tech LLC is a defense technology company that specializes in researching, developing, and commercializing innovative solutions for national security and biodefense applications. Founded in 2013 and headquartered in Philadelphia, Pennsylvania, Zeteo Tech focuses on countering unconventional threats through advanced technologies in applied chemical and biological sciences, high-performance distributed sensor systems, and biological mass spectrometry. The company develops a range of products, including instruments for assessing toxins, air and water purification systems, and technologies for remote detection and decontamination. Zeteo Tech serves a diverse clientele, including government agencies and private companies in the United States, leveraging a wide network of affiliates to facilitate prototyping and deployment of its solutions. Its innovations aim to enhance the detection and response capabilities in operational environments, particularly in identifying bio-threats and infectious diseases.

Empo Health specializes in remote patient monitoring, focusing on diabetic foot health. They develop full-color imaging scales for home use, enabling patients and clinicians to access reliable visual data outside clinical settings.

Infusense develops a biosensor platform that employs electrochemistry for precise quantification of lipophilic drugs. This technology enables rapid, sensitive sample analysis, allowing healthcare providers and researchers to perform drug detection and analysis with laboratory-grade accuracy in a portable format.

Frontier Bio Corporation is a biotechnology company based in Oakland, California, focused on developing and manufacturing advanced bioprinting technologies. Founded in 2018, the company specializes in creating lab-grown human tissues as an ethical alternative to animal studies. Its flagship product, the FLUX-1, is a 3D bioprinter that integrates conventional bioprinting methods with electro-hydrodynamic printing capabilities. This device enables the bioprinting of complex tissues such as skin, cartilage, and bone, and allows for applications in drug toxicity testing, tissue implants, drug screening, disease modeling, and prosthetics. By providing a means to produce human tissues with complete cell survivability, Frontier Bio aims to enhance the healthcare industry's ability to replace animal testing and address the organ transplant waitlist.

Compact Medical Solutions develops a medical bag-valve-mask used to assist patients experiencing emergency breathing issues. The ultra-compact device aims to improve resuscitation by preventing hyperventilation and enabling medical personnel to safely ventilate patients whose breathing is compromised. Founded in 2016 and based in Indianapolis, Indiana, the company focuses on creating portable respiratory support tools for first responders and healthcare providers.

Ecate is a Los Angeles-based company established in 2020, focused on developing innovative medical devices that create organo-robotic interfaces. The company aims to enhance human capabilities by integrating machine intelligence with biological systems. Specifically, Ecate is working on advanced neural interfaces that utilize nanoparticles and nanotechnology to facilitate communication between injured sites and the central nervous system. By employing customized nanopatterned electrodes, Ecate's technology seeks to restore sensory and motor functions for paralyzed patients, thereby helping them regain control over their lost abilities.

ZelosDx is a company focused on developing neurodiagnostic technologies, specifically blood testing products aimed at advancing research in brain health and disease. It offers proprietary technology that allows research collaborators to license and adapt blood testing kits and automated laboratory equipment. Additionally, the company provides pharmaceutical partners with biomarker technology essential for drug discovery tools. By delivering critical data for diagnosis, monitoring, and assessing therapeutic responses, ZelosDx supports researchers and pharmaceutical companies in making significant breakthroughs in understanding and treating brain-related conditions.

Samay specializes in remote respiratory health management. It develops AI-enabled wearable devices that monitor pulmonary volumes, trapped air, heart rates, breathing sounds, and lung temperature. This enables users to analyze their respiratory data and helps prevent respiratory diseases.

HC Simulation, founded in 2011 and based in Canton, Mississippi, focuses on developing advanced products that utilize the HumMod engine to deliver high-quality simulations of human physiology. The company's offerings enable users to explore physiological interactions that may be difficult to observe in traditional settings. By providing a platform for realistic modeling, HC Simulation supports the ideation, development, and prediction processes for innovative medical devices and pharmaceuticals.

Hermes Life Sciences develops solutions to improve the accuracy and accessibility of blood testing at the point of care. The company was founded by Sasank Vemulapati.

LumenAstra, established in 2020 and headquartered in Longmont, Colorado, specializes in the development of non-invasive, wearable deep-tissue temperature sensors. These devices are designed to accurately measure internal temperatures from external locations, serving diverse applications such as cancer hyperthermia therapy, hypothermia for aortic dissection repair, brain temperature monitoring for newborns, and heat stress monitoring in high-risk environments like military operations or hazardous workplaces. The company's innovative sensor technology enables medical professionals to better protect patients from potential harm caused by extreme temperatures.

Emagine Solutions Technology, LLC is a Tucson, Arizona-based company specializing in mobile ultrasound imaging technology. Its flagship product, VistaScan, converts standard mobile devices into advanced ultrasound imaging tools, enhancing diagnostic capabilities in medical settings. The company is developing its innovative technology at the Arizona Center for Innovation, a business incubator located within the UA Tech Park, where it benefits from various business assistance programs and facilities designed to support emerging technology firms. Emagine Solutions Technology aims to improve healthcare delivery through its cutting-edge solutions.

Founded in 2019, Sequitur Health specializes in developing innovative medical devices aimed at saving and enhancing lives. Based in Scottsdale, Arizona.