National Science Foundation

PediaMetrix Inc. is a company focused on developing innovative digital solutions for pediatric head measurement and monitoring. Founded in 2018 by alumni from Johns Hopkins, NIH, and Oxford, the company is based in Rockville, Maryland. Its primary product, SoftSpot, is a mobile application that leverages artificial intelligence and computer vision to provide accurate measurements of infants' head shapes. This app allows parents to receive personalized repositioning instructions and enables pediatricians to access easy-to-understand data analysis, facilitating timely and effective care. By focusing on early detection and management of head shape abnormalities, PediaMetrix aims to enhance healthcare outcomes and reduce costs associated with pediatric care.

The University of Washington is a prominent educational institution located in Seattle, Washington, founded in 1861. It offers a diverse range of undergraduate, graduate, and research programs across various fields, including business, social sciences, science, law, medicine, and public affairs. The university comprises several specialized schools, such as the College of Engineering, School of Dentistry, School of Pharmacy, School of Public Health and Community Medicine, School of Business, School of Humanities and Sciences, School of Law, School of Nursing, and College of Ocean and Fishery Sciences. In addition to its academic offerings, the university is dedicated to fostering innovation through CoMotion, which provides resources and support to help researchers and students translate their ideas into tangible societal and economic benefits.

The University of Michigan’s programs consistently places high in national rankings. Especially renowned are the Stephen Ross School of Business, the College of Engineering, The Law and Medical Schools, and the Musical Theatre program. There is also a strong film presence in Ann Arbor, with many major motion pictures being shot there and the annual Ann Arbor Film Festival, which brings in filmmakers from all over the world.

Serious research-based academics in Technology and the Engineering, Biological and Computer Sciences on a remodeled, state-of-the-art campus is what you will find at New Jersey Institute of Technology (NJIT) in Newark, New Jersey. Applied Physics, Biocomplexity, Biomedical Engineering, Civil Engineering, Mathematical Engineering and Medical Informatics Technology are some of the more than 70 undergraduate degrees offered at NJIT. There are also more than 15 graduate programs. Not only do nearly 100% of faculty hold doctorates, but they also work on pioneering research with students and with local businesses and organizations as well. Research areas include such fields as Biological Sciences, Biomedical Studies, Nanotechnologies and Wireless Communications. Opportunities for work abound for NJIT grads in great part because of the quality of student training and the reputation of the school. Also important are the internships, which the school arranges for students while they’re still studying. Classrooms and research centers aren’t the only place on the NJIT campus that employ the most current technologies. The renovated campus recreation areas, computer labs, and restaurants add to the contemporary look and feel of the NJIT experience. Since Newark is the largest city in New Jersey there are also many employment opportunities available in the area. With its restaurants and cultural activities, Newark also provides much in the way of recreation and culture. New York City is also only 20 minutes away, so there is even more to be found in the off-campus experience. Admission to NJIT is competitive and undergraduates who are accepted usually have high grades and test scores. Many eligible undergraduates receive some form of financial aid.

Remedium Bio is a Boston-based gene therapy company dedicated to developing curative treatments for various debilitating conditions. The company employs a modular approach to research and development, utilizing established technologies in innovative ways to address well-understood disease mechanisms. By focusing on clinically validated molecules and targeted treatment strategies, Remedium Bio aims to create effective therapies for conditions within rheumatology, endocrinology, and neurology. Its pipeline includes promising gene therapy candidates designed to tackle a wide range of diseases, including immune and age-related disorders.

Quantivly, Inc. is a technology company based in Somerville, Massachusetts, that specializes in artificial intelligence solutions for radiology. Founded in 2019, it focuses on developing software that manages and analyzes MRI imaging workflows. The company's platform enables radiology providers to access a vendor-neutral, granular source of operational data by analyzing and harmonizing scanner information. This capability supports radiology departments and imaging centers in making data-driven decisions, improving operational efficiency, and enhancing patient-centered healthcare. By offering tools for data liquidity and analysis, Quantivly aims to increase access to medical imaging and drive advancements in research and patient care within the radiology sector.

The University of Michigan’s programs consistently places high in national rankings. Especially renowned are the Stephen Ross School of Business, the College of Engineering, The Law and Medical Schools, and the Musical Theatre program. There is also a strong film presence in Ann Arbor, with many major motion pictures being shot there and the annual Ann Arbor Film Festival, which brings in filmmakers from all over the world.

The University of Washington is a prominent educational institution located in Seattle, Washington, founded in 1861. It offers a diverse range of undergraduate, graduate, and research programs across various fields, including business, social sciences, science, law, medicine, and public affairs. The university comprises several specialized schools, such as the College of Engineering, School of Dentistry, School of Pharmacy, School of Public Health and Community Medicine, School of Business, School of Humanities and Sciences, School of Law, School of Nursing, and College of Ocean and Fishery Sciences. In addition to its academic offerings, the university is dedicated to fostering innovation through CoMotion, which provides resources and support to help researchers and students translate their ideas into tangible societal and economic benefits.

Case Western Reserve University, located in Cleveland's University Circle, is an independent research institution established in 1843. It encompasses various schools and colleges, including the School of Medicine, School of Law, Case School of Engineering, College of Arts and Sciences, Frances Payne Bolton School of Nursing, Mandel School of Applied Social Sciences, School of Dental Medicine, and Weatherhead School of Management. The university is known for its excellence in medical education and biomedical research, with the School of Medicine recognized for its contributions to medical discoveries and training future physicians. The School of Law offers nationally ranked programs in international law, health law, and intellectual property law, integrating leadership courses and practical experiences into its curriculum. Case Western Reserve University is a member of the Association of American Universities and maintains full accreditation from the Higher Learning Commission, reflecting its commitment to educational quality and research excellence.

University of Minnesota provides baccalaureate, master’s, and doctoral degrees in medicine, business, law, liberal arts, science, engineering, and architecture fields. They also provide education services to communities through science-based knowledge and training.

Malcova is an early-stage medical device startup focused on developing advanced imaging solutions for the detection and diagnosis of breast cancer, particularly in women with dense breast tissue. The company employs its proprietary Narrow-Beam Computed Tomography technology, which enhances the effectiveness of medical imaging compared to traditional methods like mammography and tomosynthesis. Additionally, Malcova integrates artificial intelligence in its software to improve the functionality of its devices. The aim is to provide clinicians with tools that facilitate accurate diagnosis while ensuring that the imaging process is safe, comfortable, and accessible for patients. Through these innovations, Malcova seeks to enhance the overall experience and outcomes for breast cancer detection and treatment.

The University of Louisville is a public research university that offers a wide range of undergraduate and graduate programs across various disciplines. It is particularly known for its contributions to health, engineering, and the humanities. The university actively engages with community partners to enhance its academic and research initiatives, thereby creating a significant impact on education, healthcare, and research industries. Additionally, the University of Louisville School of Dentistry serves as a specialized institute within the university, focusing on dental education and training.

Lilu Inc. is a women’s health company based in New York, specializing in innovative solutions for new mothers. Founded in 2016, the company develops tech-enabled devices aimed at improving the breastfeeding experience. Its flagship product, the Lilu massage bra, is an FDA Class device that employs patented pneumatic massage technology to mimic natural breastfeeding motions, thereby increasing milk output and reducing discomfort associated with traditional breast pumps. Lilu's products, including the massage bra and pumping cover, are sold online and have received positive feedback from customers, who appreciate their effectiveness and user-friendly design. By addressing common challenges faced by breastfeeding mothers, Lilu seeks to empower women while promoting a more manageable breastfeeding journey.

Metfora is focused on developing a blood test designed to identify chronic lung and heart disorders, as well as cancers, in their early stages. The company employs artificial intelligence to analyze patterns in circulating metabolites within a patient's blood, enabling the detection of diseases that may not present significant symptoms initially. This innovative approach aims to assist both doctors and patients by providing timely insights for diagnosing serious health conditions, ultimately enhancing early intervention and treatment options.

ReSuture is a company that specializes in creating high-fidelity physical simulations for surgical training, particularly focusing on open vascular procedures. Established in 2019, its primary goal is to enhance patient outcomes and minimize surgical complications by providing a superior training experience for aspiring surgeons. The company develops advanced surgical instruments that address challenges in medical simulation, allowing users to practice vascular surgical skills in a controlled environment. These instruments replicate the mechanical properties of human vascular tissue, enabling realistic simulations that improve psychomotor skills and reduce training time for medical practitioners.

BLOCKsyncop is developing a non-invasive real-time tool for the anesthesiologist.

PneumoNIX Medical is focused on creating gel-based technologies aimed at preventing complications related to percutaneous procedures, particularly in the context of soft tissue biopsies. The company's innovative medical devices are designed to minimize the risk of collapsed lung complications that may occur during CT-guided lung biopsies. By addressing these critical issues, PneumoNIX Medical seeks to enhance patient safety and improve outcomes in medical interventions that involve needle insertions.

Vivifi Medical develops a laparoscopic device that allows for the quick connection of two blood vessels. The company is headquartered in Houston, Texas.

The University of Louisville is a public research university that offers a wide range of undergraduate and graduate programs across various disciplines. It is particularly known for its contributions to health, engineering, and the humanities. The university actively engages with community partners to enhance its academic and research initiatives, thereby creating a significant impact on education, healthcare, and research industries. Additionally, the University of Louisville School of Dentistry serves as a specialized institute within the university, focusing on dental education and training.

Atom Bioworks focuses on developing a pattern-recognition enabled platform that combines DNA, antibody mimics, and advanced computational techniques for the detection and treatment of infectious diseases and cancer. The platform utilizes computational biology, quantum chemistry, software, and machine learning to identify specific surface protein patterns associated with diseases. By creating corresponding pattern-matching constructs, Atom Bioworks aims to enhance researchers' capabilities in early diagnosis and therapeutic interventions, ultimately improving medical applications in the fight against infectious diseases and cancer.

The University of Michigan’s programs consistently places high in national rankings. Especially renowned are the Stephen Ross School of Business, the College of Engineering, The Law and Medical Schools, and the Musical Theatre program. There is also a strong film presence in Ann Arbor, with many major motion pictures being shot there and the annual Ann Arbor Film Festival, which brings in filmmakers from all over the world.

Bespoke Biotherapeutics provides an effective natural immune response and overcomes the limitations of currently approved immunotherapies against cancer by inventing novel, customised living drugs called engineered B-cell therapeutics. They offer customised B-cell sourcing, isolation, activation, culture expansion, and non-viral genetic engineering methodologies uniquely suited to optimise commercial B-cell products for infusion.

AngioInsight is a fully automated computer-based platform to assist with coronary angiogram video interpretation.

Tiny Cargo specializes in a unique drug delivery system utilizing non-immunogenic bovine milk-derived exosomes. This innovative approach allows for the effective oral or intravenous administration of potent therapeutics. The company focuses on delivering treatments for various serious health conditions, including ischemic heart disease, gastrointestinal radiation disease, and glioblastoma multiforme, among others. By leveraging its technology, Tiny Cargo aims to enhance the delivery of peptide drugs, making it applicable to a wide range of current peptide therapeutics and improving patient outcomes in the treatment of neurological and other pathologies.

Claria Medical is a pre-commercial medical device start-up focused on developing innovative solutions for women's healthcare, specifically targeting unmet needs in gynecologic surgery. The company specializes in creating minimally invasive surgical tools designed to enhance procedures such as hysterectomy and myomectomy. Claria Medical has received recognition for its early achievements, including a “Safer Technologies Designation” from the U.S. Food and Drug Administration. Additionally, the company has secured funding through private investments as well as grants from the National Science Foundation and the National Institutes of Health to support its product development efforts. By providing specialized surgical assistance, Claria Medical aims to improve outcomes for women undergoing these procedures.

CardioPhi aims to improve outcomes for the millions of people with cardiac arrhythmias and reduce public spending on cardiovascular diseases. They are harvard innovation labs.

Oculogenex is a biopharmaceutical company that specializes in gene therapy for the treatment of retinal disorders. The company was founded in 2020 and is headquartered in La Habra, California.

JelikaLite specializes in developing medical equipment for children with autism spectrum disorders, focusing on non-invasive methods to enhance brain health. Their primary product is a wearable device that integrates infrared light, EEG sensors, and an artificial intelligence personalization platform. This therapeutic device aims to reduce the symptoms of autism by promoting improvements in speech, decreasing anxiety, and enhancing responsiveness in pediatric patients. By utilizing innovative therapies, JelikaLite seeks to provide lasting benefits for children dealing with autism, emphasizing a commitment to advancing pediatric neurological health.

Relavo, LLC, founded in 2018 and based in Baltimore, Maryland, is a medical device company focused on improving the treatment of kidney failure patients through innovative technology. The company's flagship product, PeritoneX, is designed to enhance home dialysis by reducing the risk of infection associated with peritoneal dialysis. This in-line connection device works by disinfecting all connection points in the dialysis system before treatment, thereby aiming to minimize the occurrence of peritonitis. Relavo's approach seeks to make home dialysis safer and more accessible for patients, ultimately improving their quality of life.

Qualia Oto is a biomedical device company focused on advanced cochlear implant technology. It utilizes its core innovations to produce top-quality, shape-changing polymers and matrix-addressed electrode arrays embedded in devices for individuals' medical and personal needs. The company's technology enables higher channel count cochlear implants and auditory brainstem implants for more precise auditory nerve stimulation and the eventual incorporation of more complex, machine learning-based stimulation. Qualia Oto was founded in 2017 in Dallas, TX.

Oxalo Therapeutics is focused on developing innovative drug therapies aimed at treating rare kidney diseases and preventing recurring kidney stones. The company specifically targets primary hyperoxaluria and other oxalate-related pathologies through a novel approach that utilizes a gut bacterium to facilitate the safe removal of oxalate from the body. By mimicking natural mechanisms, Oxalo Therapeutics seeks to provide effective treatment options for patients suffering from conditions associated with high levels of oxalate, thereby improving their quality of life and reducing the incidence of kidney stone recurrence. The company's expertise in the microbiome and translational research underpins its commitment to advancing early-stage technology in the field of kidney health.

Uniphage is a biotech company that eliminates bacterial infections by combining the power of bacteriophages with artificial intelligence. Their first target disease is citrus greening, an incurable and debilitating disease that costs the United States more than $2 billion each year. Uniphage created the first commercially effective models for computationally predicting safe bacterial viruses against target bacterial infections, as well as discovered a variety of targets. This enables them to deliver new antimicrobial, safe, and precise products to market much more quickly.

Creative BioTherapeutics is a biotechnology company dedicated to developing innovative therapies for cancer and viral diseases. The company aims to transform cancer and viral disease research by targeting the fundamental issues of immune evasion and drug resistance. With a focus on recurrent and drug-resistant cancers, Creative BioTherapeutics is creating first-in-class biologics designed to address critical needs in treatment, particularly for patients with recurrent metastatic breast cancer. This approach not only seeks to enhance tumor regression but also holds the potential for cures in both adult and childhood cancers, thereby improving treatment options for patients facing these challenging conditions.

Simmbion specializes in innovative therapeutic solutions by utilizing symbionts to manufacture therapeutic agents directly within the human body, effectively transforming it into a living pharmacy. This technology aims to eliminate the challenges associated with traditional therapy manufacturing, such as the need for complex production processes, repeated injections, and temperature-sensitive storage. By providing a single injection that lasts up to 12 weeks, Simmbion's approach addresses supply chain disruptions and enhances affordability and accessibility of cell therapies for diverse patient populations. Their adaptable and universally immune compatible systems focus on delivering biological drugs directly in vivo, supporting a patient-centric and outcome-driven healthcare model while minimizing the risks of infections and immune rejection.

Cryptyx Bioscience is a genetics-free, cloning-free, bioactivity-first platform for accessing hidden therapeutic natural products encoded in bacteria. They utilize a natural product drug discovery platform aimed at activating silent biosynthetic gene clusters in bacteria and at unlocking the full potential of any culturable microbe.

Medical Device company developing the most affordable, high-end, ultraportable ventilator on the market.

Iaso Therapeutics, founded in 2018 and based in East Lansing, Michigan, is a biotechnology company focused on developing vaccines aimed at improving human health and treating infectious diseases. The company’s platform is dedicated to creating vaccines for serious illnesses, including smallpox, yellow fever, and tetanus. By providing healthcare professionals with innovative technologies, Iaso Therapeutics seeks to enhance public health outcomes and address critical health challenges.

Ai-Ris offers automated retinal examinations for primary care. Their retinal imaging system allows general practitioners to screen for diabetic retinopathy without the presence of a specialist. This system consists of a portable headset that uses machine learning algorithms to classify images of the retina of patients without dilating their pupils.

Hypersound Medical provides neuromodulatory methods using neurostimulation principles. They concern peripheral nerve stimulation, spinal cord stimulation, deep brain stimulation, motor cortex stimulation, and repetitive transcranial magnetic stimulation.

Lura Health has developed a groundbreaking non-invasive health monitoring platform that utilizes saliva as a diagnostic fluid, aiming to enhance clinical outcomes in chronic disease management. Founded in 2017 and based in Cambridge, Massachusetts, the company targets various chronic disease markets, including heart disease, chronic kidney disease, diabetes, and tooth decay. Its innovative sensors are integrated into patient-friendly orthodontic devices such as removable retainers and fixed braces. These sensors continuously measure analytes in saliva and automatically transmit data to a smartphone application, allowing users to track key diagnostic metrics related to their oral health. By enabling individuals to monitor their health in real-time, Lura Health seeks to improve personal health management and empower users to take charge of their well-being.

Acrigen Biosciences is dedicated to making gene editing safe. It develops technologies to improve efficiency and enhance the safety of CRISPR-Cas based gene editing. CRISPR-Cas system which enables the precise enzymatic editing of genes is one of the most exciting and promising techniques to be developed in the last few years with the capability to prevent or cure many devastating diseases. It was founded in 2019 and is headquartered in Berkeley, California.

Levisonics is a manufacturer of advanced blood coagulation instruments that specialize in non-contact analysis for blood coagulation and fluid quality control testing. Their products facilitate the assessment of bleeding and thrombosis risks through innovative fluid rheological measurement techniques. In addition to medical applications, Levisonics' technology can be employed in real-time monitoring of the quality of food, liquid, and gel products during production or processing, ensuring safety and compliance in various industries.

Visicell Medical is a company focused on developing innovative medical imaging technology that enhances the early detection and diagnosis of diseases. It specializes in creating safe and biodegradable stem cell tracking tools, which facilitate real-time monitoring of stem cells implanted in patients. These tools are designed for use in both clinical and pre-clinical settings, allowing healthcare professionals to track stem cell progress effectively. In addition to stem cell tracking, Visicell Medical offers specialized image capture systems and analysis tools that provide high-resolution, three-dimensional views of tissues and cells. This technology aids in the identification of abnormalities, enabling earlier intervention and improved treatment outcomes for patients, while also aiming to reduce overall healthcare costs.

Cytocybernetics is a biotechnology company that specializes in cellular electrophysiology. The company has developed the Cybercyte, a user-friendly plug-and-play dynamic clamp system designed for ease of use in research settings. In addition to its innovative products, Cytocybernetics offers a comprehensive range of contract research organization (CRO) services, which include FDA-mandated drug safety screening, custom electrophysiology, custom modeling, and custom analysis. These services are aimed at assisting clients in the development and evaluation of various cellular products, ensuring that they meet regulatory requirements and scientific standards.

Amphix Bio is engaged in the development of advanced therapeutic materials aimed at regenerative medicine. The company specializes in creating nanofiber materials that replicate the structure and dynamic characteristics of human tissues. By integrating biological signals, these materials instruct cells to activate regenerative processes. Amphix Bio's innovations enable the development of therapies designed to repair a variety of tissues, including bone, cartilage, muscle, cardiovascular tissues, and the brain and spinal cord. The promising results observed in both preclinical and clinical trials highlight the potential of Amphix Bio's approach in transforming therapeutic applications in medicine.

UCHU Biosensors develops a platform of tooth mounted sensors to effortlessly track health through saliva.

Juggernaut Life Sciences provides novel technological solutions to common medical problems. They provide fields of medicine, image guidance, robotics, and artificial intelligence.

Taurus Diagnostics is a health-tech company focused on enhancing the diagnostic process for men suspected of having prostate cancer. The company employs data-centric artificial intelligence solutions to improve the accuracy of magnetic resonance imaging (MRI), which helps prevent unnecessary biopsies. Its AI algorithm has been trained on a vast dataset of patient examples to reliably detect lesions indicative of prostate cancer. This technology allows physicians to identify patients who require biopsies more effectively and provides precise locations of the detected lesions, thereby supporting better clinical decision-making.

InvVax, Inc. is a vaccine development company based in Los Angeles, California, founded in 2012. The company focuses on creating innovative vaccines, with its primary product being a universal influenza vaccine aimed at preventing pandemics. Utilizing a proprietary platform, InvVax's technology analyzes influenza proteins to address virus mutations, thereby enhancing the effectiveness of vaccines. In addition to its work on influenza, InvVax is exploring vaccine candidates for other viral infections, including HIV, Hepatitis B, and Hepatitis C.

Nostopharma specializes in developing treatments for pathologic bone growth, aiming to prevent rare bone diseases and minimize complications from traumatic injuries. The company offers a nanoparticle drug delivery system that addresses soft tissue trauma complications, facilitating the formation of new bone after surgeries, burns, and other traumatic incidents. By enhancing the recovery process, Nostopharma's innovative approach supports healthcare providers in improving clinical outcomes for patients undergoing surgical procedures related to post-traumatic injuries. Additionally, the company's efforts contribute to reducing rehabilitation costs for society.

Intelligent Medicine specializes in software and simulation services focused on enhancing safety in medical environments through innovative technologies. The company has developed a simulation platform that enables architects and facility stakeholders to evaluate and optimize building designs and operational protocols. By testing various designs and protocols, the platform helps to identify areas for improvement, thereby reducing the likelihood of infectious disease transmission and alleviating user congestion. This capability allows for a rapid feedback loop, supporting the planning and implementation of effective safety policies and design strategies to improve overall outcomes in healthcare settings.

Aurie is a medical device company based in New York, established in 2018. It focuses on developing a reusable urinary catheterization system aimed at improving the quality of life for individuals with disabilities. By providing a convenient, discreet, and hygienic catheterization option, Aurie seeks to reduce the risk of infections and enhance users' confidence and control over their healthcare needs. The company's innovative approach empowers users to manage their condition more effectively, enabling them to lead active and fulfilling lives.

SafeBVM is a medical device company focused on enhancing patient safety during manual ventilation. Its flagship product, Sotair, is designed to mitigate the risks associated with excessive ventilation, which can lead to complications such as stomach insufflation and acute respiratory distress syndrome. The device employs a flow-blocking and pressure-control valve mechanism that regulates airflow and ensures optimal ventilation parameters based on individual patient needs, including airway resistance and lung compliance. By addressing the issue of inadvertent hyperventilation, SafeBVM aims to improve the safety and effectiveness of manual resuscitation techniques used by healthcare providers.

PediaMetrix Inc. is a company focused on developing innovative digital solutions for pediatric head measurement and monitoring. Founded in 2018 by alumni from Johns Hopkins, NIH, and Oxford, the company is based in Rockville, Maryland. Its primary product, SoftSpot, is a mobile application that leverages artificial intelligence and computer vision to provide accurate measurements of infants' head shapes. This app allows parents to receive personalized repositioning instructions and enables pediatricians to access easy-to-understand data analysis, facilitating timely and effective care. By focusing on early detection and management of head shape abnormalities, PediaMetrix aims to enhance healthcare outcomes and reduce costs associated with pediatric care.

Alienbyte provides medical images and labels. Their labels are required for sophisticated analysis of human or animal bodies or training AI algorithms. They use algorithmic tricks, including AI, to speed up labeling.

Oncurie develops targeted radionuclide therapy to create a cure for metastatic cancer through the use of novel molecular radionuclide technology, enabling healthcare providers to cure their patients. They are creating the technology to deliver radionuclides selectively to metastatic tissues.

Optical Waters provides integral disinfection solutions so companies can deliver clean and safe products to their end users. Their patent-pending optical fibres emit germicidal ultraviolet light along their entire length, like a glowstick, inactivating microorganisms in their vicinity. They are integratable, germicidal optical fibres that are stable in water and can be inserted into complex geometries and narrow-diameter channels such as piping or tubing.

DNALite Therapeutics, Inc. is a biopharmaceutical company focused on developing gene therapy treatments specifically for the gastrointestinal tract. Founded in 2016 and based in San Francisco, California, DNALite utilizes innovative oral lipid nanoparticle technology to deliver mRNA and pDNA directly to intestinal stem cells. This approach targets the underlying causes of diseases such as Familial Adenomatous Polyposis, a hereditary form of colorectal cancer that often necessitates invasive surgeries in adolescents. By enabling the intestinal tract to secrete therapeutic proteins into the bloodstream, DNALite aims to transform conventional protein biologics into oral medications, potentially improving patient outcomes and accessibility to treatment.

Bired Imaging specializes in infrared imaging technology aimed at enhancing breast cancer detection and localization, particularly in patients with dense breast tissue. Their medical imaging platform employs thermography and a proprietary computerized detection algorithm, which allows for the accurate identification of tumor size and location. This innovative approach enables healthcare professionals to detect high-risk patients at earlier stages, improving screening efficacy while also being cost-effective. Bired Imaging's solutions serve as an important adjunctive technology in breast cancer screening, contributing to more precise diagnostic processes.

PZA Innovation is a biotechnology company focused on developing a reliable testing method for pyrazinamide, a first-line drug used in tuberculosis treatment. The company employs reverse engineering techniques to determine the specific conditions under which pyrazinamide is effective in vitro, thereby enhancing its action against mycobacterium tuberculosis in a living host. By improving the understanding of pyrazinamide susceptibility, PZA Innovation aims to enable healthcare professionals to offer a next-generation treatment that could potentially shorten the duration of tuberculosis therapy for patients.

IntuiTap Medical is focused on improving the accuracy and efficiency of spinal puncture procedures, which often suffer from challenges related to precision and patient discomfort. The company has developed a handheld device that is the first comprehensive solution for spinal-needle placements. This innovative device integrates imaging of the spine with needle guidance and analytics, allowing healthcare professionals to perform lumbar punctures, spinal anesthesia, and epidurals with greater confidence. By streamlining these procedures, IntuiTap Medical aims to enhance the overall experience for both clinicians and patients while reducing procedural costs.

Huxley Medical is a private company focused on the development of medical devices. The company operates a flexible medical platform that aims to ensure continuity of care for patients, regardless of their location or healthcare system. By collaborating with leading clinicians and basic science researchers, Huxley Medical creates and markets innovative devices and algorithms. This approach enhances user access to a wide range of disease diagnoses and treatment options, ultimately improving patient care and outcomes.

Nanopath Inc. is a molecular diagnostics company focused on enhancing women's health through rapid and precise testing. By utilizing advancements in bioengineering and nanotechnology, the company specializes in the sensitive detection of viral, bacterial, and fungal pathogens without relying on nucleic acid amplification techniques. This innovative approach allows for the delivery of granular and clinically actionable information, thereby improving traditional testing methodologies and enabling healthcare providers to make informed decisions more swiftly.

Vulcan Biologics is a biotechnology company based in Irvine, California, established in 2019. It specializes in the modulation of the microbiome through the use of bacteriophages, which are viruses that specifically infect bacteria without harming human cells. This innovative platform aims to achieve stable and persistent changes in the gut microbiome, facilitating the treatment of gluten-related disorders such as gluten sensitivity and celiac disease. By altering the composition of gut bacteria, Vulcan Biologics enables healthcare providers to offer targeted therapeutic solutions for individuals affected by these conditions.

Astek Diagnostics is focused on developing a precision diagnostic platform that assists physicians in prescribing appropriate antibiotics for patients suffering from bacterial sepsis within one hour. The company’s technology utilizes a single-use cartridge to rapidly detect bacterial infections in urine by measuring the oxygen consumption of various bacterial species. This innovative approach not only speeds up the identification process but also aids in combating antibiotic resistance through effective susceptibility testing.

Averto Medical is a manufacturer of medical devices focused on addressing gastrointestinal diseases. The company specializes in developing innovative solutions designed to facilitate minimally invasive colorectal tumor removal, which aims to reduce the need for multiple surgical procedures and associated complications. By providing effective medical care options for patients suffering from gastrointestinal disorders, Averto Medical seeks to improve patient outcomes and streamline treatment processes in this critical area of healthcare.

CorInnova Incorporated provides device-based therapies for the treatment of congestive heart failure. CorInnova’s non-blood-contacting soft robotic cardiac assist device could potentially triple or quadruple the number of heart failure patients who could be eligible for such a life-saving device therapy.”

OPOS provides opioid treatment to patients while maintaining regulatory compliance. Their services generate revenue by reducing administrative overhead, reducing prescribing risk, and reducing administrative overhead.

Synvivia, Inc. is a biotechnology company founded in 2016 and based in Berkeley, California. It specializes in developing synthetic biology products, particularly ON-OFF switches for genetically engineered organisms. These protein switches can be controlled by small molecules, allowing for precise manipulation of biological functions. By integrating these switches into organisms, Synvivia aims to create engineered life forms that can be effectively used in healthcare. The company also focuses on generating biosensors that enhance enzymatic activities, facilitating easier disease diagnosis and enabling healthcare providers to deliver appropriate treatments.

Cision Vision is a developer and supplier of advanced imaging medical products focused on enhancing the examination of lymph nodes. Their innovative technology allows pathologists to visualize, scan, and record lymph nodes in real time with high contrast, without the need for injections or radiation. This capability supports the modernization of pathology practices, ensuring consistency and high-quality care in medical diagnostics. By providing these biotechnology tools, Cision Vision aims to improve the efficiency and accuracy of lymph node assessments in clinical settings.

Pragma Health provides digital healthcare services. They permit users to perform different tests for cardiovascular, hematology, infectious diseases, and others in the privacy of their home and provide accurate, immediate results, enabling them to get a convenient, cost-effective, and accurate healthcare testing process.

Aracari Biosciences specializes in developing advanced 3D Vascularized Micro-Organ platforms aimed at improving the drug discovery process. These platforms enhance the biological authenticity of pre-clinical testing by allowing for real-time imaging of vessel morphology, which facilitates the investigation of lead compound efficacy against tumors in a three-dimensional environment. The technology is designed to adapt to various physiological conditions and can be perfused with fluorophore-tagged dextrans of different molecular weights. This capability assists pharmaceutical companies in making informed decisions and accelerates the development of new drugs.

Green Sun Medical, LLC is a medical device company based in Fort Collins, Colorado, specializing in the design, development, and manufacturing of orthotic braces for treating Adolescent Idiopathic Scoliosis (AIS) and Kyphosis. Founded in 2013, the company focuses on creating a dynamic spinal alignment brace that applies continuous corrective pressure to the spine, assisting in the management of spinal deformities. This innovative brace not only promotes effective treatment but also enables physicians to monitor its performance remotely in real-time, thereby enhancing patient care and recovery outcomes. Green Sun Medical is dedicated to advancing spinal health through its technology-driven solutions.

Felix Biotechnology is working to accelerate the deployment of novel biotherapeutics to manage infectious diseases. Felix Biotechnology's bio-therapeutics targets antibiotic-resistant bacteria to manage infectious diseases precisely and effectively, allowing healthcare professionals to manage urgent microbial challenges in human health.

Biochip Labs provides blood disorder testing for conditions like sickle cell disease and thalassemia. The company was founded in 2019 and is headquartered in Cleveland, Ohio.

CollaMedix specializes in the development of collagen-based medical devices aimed at addressing soft tissue repair and augmentation. The company focuses on treating stress urinary incontinence in women, a condition that results in urine leakage during activities such as laughing, coughing, sneezing, lifting, and exercising. CollaMedix utilizes proprietary collagen materials to create a bio-inductive scaffold, which is a strong fabric designed to support human tissue and facilitate rapid cell integration. This innovative approach allows researchers to explore new and effective treatments for female pelvic health, ensuring safety and efficacy in their medical solutions.

TRGel, founded in 2010 and located in Irvine, California, specializes in the development of glucose-based biopolymers designed to serve as an alternative to calcium alginate for encapsulation purposes. The company’s biopolymers are crafted from biocompatible materials, which encompass thermoresponsive hydrogels with adjustable gelation temperatures. These innovative biopolymers enable researchers to utilize them effectively as vehicles for drug delivery, expanding the possibilities for applications in various fields.

Kodikaz goal is to move from incremental cancer therapies with devastating side effects to durable cures through targeted therapies that can eradicate cancers. Zip-Code™ Technology platform is a first-in-class, cell-specific delivery system that can be used for a broad range of gene therapy applications. Because the Zip-Codes ™ is derived from an endogenous human mechanism it avoids all of the challenges of viral delivery approaches. The Zip-Codes ™ are universally applicable and specific for each cell type.

Developed by leaders of the Johns Hopkins University School of Medicine, MileMarker™ is an on the job, real-time assessment software for medical training to help universities, attendings and residents meet evolving regulatory requirements for competency-based learning, while reducing training costs, facilitating communication and increasing efficiency. MileMarker solves multiple problems in the healthcare industry, including economic pressures of lowering training and medical costs as well as evolving medical education requirements. MileMarker can increase revenue by $500K/residency program/year and can reduce training time by 8-25%. Accessible by any mobile device or computer, MileMarker captures real-time data on resident performance in the operating room. It allows residents to log operative cases and provide self-assessments of their performance, after which the attending surgeon logs an assessment and maps the case to a milestone. These activities can be completed within the workflow and under 1 minute. Residents and faculty can monitor resident performance over time and compare individual residents’ progress to their peers. Data is available in real-time and can be viewed by individual case, on the CPT code level, and by ACGME Milestone for rapid review of resident progress.

NanoSpy, Inc., founded in 2017, specializes in rapid pathogen detection through advanced biosensor technology. The company has developed proprietary and patent-pending biosensors that enable the detection of targeted pathogens with high sensitivity and specificity. These biosensors can identify live bacteria at concentrations as low as 5 CFU/mL within just 20 minutes, eliminating the need for time-consuming enrichment processes, hazardous reagents, or laboratory settings. By utilizing standard sampling methods and low-cost supplies, NanoSpy's technology allows for quick and accurate results, thereby enhancing safety testing for researchers and streamlining the detection process. This innovative approach represents a significant advancement in the field of pathogen detection.

TheraCea Pharma is a biotechnology company based in Tucson that focuses on developing precision medicine for individuals with neurological disorders. As a spin-off from the University of Arizona, the company has developed and licensed advanced radiochemistry technology that enables efficient and rapid fluorine-18 radiolabeling of biomolecules. This innovative approach supports both clinical and research applications, particularly in the context of neurological conditions. TheraCea Pharma's treatments aim to counteract dyskinesia, a side effect commonly associated with L-dopa, the standard treatment for Parkinson's disease. By providing new diagnostic agents, the company enhances medical professionals' capabilities in detecting not only neurological disorders but also cancer, thereby contributing to improved healthcare outcomes.

Nano PharmaSolutions specializes in enhancing the bioavailability of insoluble drugs through its proprietary nanoformulation technology. The company has developed an innovative phase-transition technology platform that significantly improves the solubility of BCS 2 and BCS 4 active pharmaceutical ingredients (APIs) without the need for excipients, which are typically used in traditional processes like spray-dry dispersion and emulsification. By vaporizing the API and depositing it onto a carrier molecule, Nano PharmaSolutions enables the production of nanoparticles that can be processed into various dosage forms. Additionally, the company focuses on delivering neurodegenerative therapeutics directly to the brain via an intranasal route, facilitating a rapid onset of action and enhancing safety profiles. Their pipeline includes treatments for conditions such as Parkinson's disease, peripheral neuropathy, and substance abuse disorders, positioning Nano PharmaSolutions as a key player in the field of nanomedicine.

Verboso specializes in developing a speech therapy platform that incorporates video games powered by artificial intelligence to create an engaging and enjoyable experience for users. The platform utilizes AI to deliver real-time, non-binary assessments of speech therapy exercises, allowing users to interact with the games while simultaneously tracking their progress and compliance. This innovative approach enables parents to actively participate in their children's speech therapy sessions, making the process more appealing and effective. Through the integration of gamification and data-driven insights, Verboso aims to enhance the overall experience of speech therapy for children.

Ancilia Biosciences focuses on developing engineered bacterial therapies aimed at treating diseases associated with the microbiome. The company specializes in creating virus-resistant live bacterial products that modulate the human microbiome, specifically targeting the viral components within the gut microbiome. By concentrating on healthy gut bacteria and their predatory phages, Ancilia engineers resistant bacterial strains to combat diseases. Its innovative approach includes the development of a new class of live biotherapeutics that allows medical professionals to target specific phages or viruses that induce lysis, with applications in immunology and oncology.

Inherent Targeting develops fluorescent contrast agents that target nerves to improve surgical outcomes. The company was founded in 2019 and is headquartered in Portland, Oregon.

LumenAstra develops a non-invasive, wearable deep-tissue temperature sensor for cancer treatment and other applications. The company was founded in 2020 with its headquarters in Longmont, Colorado.

MedChem Partners is a medicinal chemistry CRO that specializes in developing small molecule therapeutics. The company was founded in 2006 and is headquartered in Lexington, Massachusetts.

Frugi Biotechnology is a synthetic biology company that creates modular, paper-based, secure diagnostics for viral outbreak management. The company was founded in 2020 and is headquartered in Ames, Iowa.

Drive Therapeutics is a new biotechnology company that strives to improve treatment for retinal diseases.

ALSUS MEDICAL offers treatment for urinary stream problems that may be weak or stop and start. In some cases, it can lead to infection, bladder stones, and reduced kidney function. They offer treatments that include medication that relaxes or shrinks the prostate, surgery, and minimally invasive surgery.

InSoma Bio integrates biology and materials science to solve problems in tissue engineering and regenerative medicine. It offers genetically engineer protein-based materials that can mimic the naturally found elastin found in extracellular tissues. The company also offers reconstructive plastic surgeries and injectable materials.

Qas.ai specialized in the creation and commercialization of software that worked in conjunction with image-guided surgical equipment. The company's multidisciplinary team includes experts in biomedical engineering, neurosurgery, and pathology.

Cordance Medical is a medical device company that develops radical therapy for a variety of CNS pathology, including primary and metastatic cancer, Alzheimer's, and Parkinson's diseases.

Avior Bio is a clinical-stage, pharmaceutical company developing drugs for distressed neurological conditions. Using its disruptive drug delivery technology – Speedit™ Transmucosal Film Technology – we are positioned to develop products that bring unsurpassed value in efficacy and safety. Avior has an excellent management team, a strong advisory board, supportive partners, dedicated scientists, and knowledgeable clinicians that position us to be successful.

Tacit Therapeutics created RNA-targeting treatments for devastating diseases. By repurposing pre-existing components of human cells, we have created the first broadly applicable and inherently non-immunogenic means to repair mutated genes. The company was founded in 2021 and is based in South San Francisco, California.

Ethos Medical Inc is a medical device company that specializes in developing ultrasound-based systems for guiding needle placement in procedures such as spinal taps and epidurals. Founded in 2018 and headquartered in Duluth, Georgia, the company has created the Iris, a handheld device that works with existing ultrasound machines to provide real-time tracking and guidance for medical practitioners. This technology aims to enhance the precision of needle-based procedures, improving both accuracy and efficiency in healthcare delivery while minimizing costs.

ThermoBeat is an energy company that will use the body's thermal energy to continuously provide energy to the pacemaker, which means that replacement will never be necessary as long as the body produces heat energy. Their technology employs a thermoelectric generator that generates power as a result of a temperature differential between opposite sides of a conductor. This power source is sufficient to power a pacemaker indefinitely, but a battery will be implanted in the event of a malfunction.

Verantos is the market leader in high-validity real-world evidence for life sciences. By incorporating robust clinical narrative data, artificial intelligence technology, and measured validity, Verantos is the first company to generate research-grade evidence at scale across all therapeutic areas. The Verantos Evidence Platform integrates heterogeneous real-world data sources and generates evidence with the accuracy necessary for market access, HEOR, medical affairs, and regulatory use.

Partillion Bioscience is an early-stage life science company focused on developing a functional single-cell analysis platform. This innovative platform utilizes a novel nano vial technology to rapidly compartmentalize and analyze millions of single cells, specifically targeting secreted proteins. By enabling detailed examination of biological functions, Partillion aims to democratize advanced single-cell assays for biotech laboratories and clients. This capability supports the development of more effective therapies for various conditions, including cancer, autoimmune diseases, and infectious diseases.

Vectech is a public benefit corporation based in Baltimore, MD, specializing in an AI-based diagnostic system for medical entomology. The company has developed an identification system that accurately determines species, sex, and other essential characteristics of mosquito and tick populations. This technology is currently deployed in seven countries and serves various clients, including municipal and national public health programs, NGOs, and malaria control initiatives. By providing tools that reduce labor costs associated with mosquito surveillance, Vectech empowers researchers and public health organizations to detect threats from mosquito-borne diseases like dengue and malaria, facilitating early intervention and customized responses to potential outbreaks.