Dynocardia is a biomedical device company developing wearable, non-invasive blood pressure monitoring technology. Its ViTrack wrist-wearable device provides direct, beat-by-beat measurement of blood pressure and tracks heart rate, respiration, and rhythm with accuracy comparable to intra-arterial lines. The platform uses a wearable optomechanical sensor to enable continuous, mobile monitoring of cardiovascular parameters. Founded in 2018, the company is headquartered in Massachusetts and focuses on meeting critical clinical needs with portable monitoring solutions.
PediaMetrix is a pediatric health technology company that develops AI-powered cranial measurement and monitoring tools to detect and manage head shape abnormalities in newborns. Its SoftSpot platform provides quantitative cranial measurements via a smartphone app, enabling at-home and in-office use, and offers data-driven guidance and repositioning instructions for parents. The system also gives pediatricians access to simplified analysis and data from the app to support clinical decisions, and is supported by FDA-cleared digital tools for pediatric head assessment. Founded in 2018, the company is based in Rockville, Maryland, and leverages computer vision and artificial intelligence to lower healthcare costs and improve outcomes in pediatric head care.
Nanopath is a molecular diagnostics company that develops innovative platforms for rapid disease diagnosis. Its technology enables point-of-care testing, eliminating the need for nucleic acid amplification and supporting multiplexed detection. This allows patients and healthcare providers to access accurate diagnostic results within standard office visits, improving healthcare outcomes.
CerFlux develops advanced cancer modeling technology to enhance understanding and treatment of cancer. Its platform uses innovative ex vivo models to evaluate therapeutic efficacy on patient tumor tissue, enabling oncology professionals to improve patient outcomes through tailored therapy approaches.
Baldwin Wallace University
Grant in 2023
Baldwin Wallace University, established in 1845 and located in Berea, Ohio, is a non-profit educational institution recognized for its strong regional college ranking by U.S. News and World Report. The university offers a diverse array of undergraduate degrees in fields such as Art History, Criminal Justice, Film Studies, and Neuroscience, along with graduate programs in Business and Education. A notable highlight is its music conservatory, which prepares students for successful careers in various music-related fields, including Broadway and music therapy. Baldwin Wallace emphasizes experiential learning, encouraging students to engage in internships that provide practical application of their studies and enhance employability. The university supports students through personalized Action Plans created in collaboration with career and academic counselors, guiding them in course selection and extracurricular involvement. With over 100 clubs, athletic teams, and residential living options, student life is vibrant and engaging. Additionally, Baldwin Wallace offers health services, personal counseling, and financial aid opportunities to ensure students have access to necessary resources throughout their education.
Tiny Cargo specializes in the isolation and application of exosomes derived from bovine milk. Their technology enables industrial-scale production of these exosomes for various purposes, including pharmaceutical drug delivery, skin repair treatments, and nutritional applications.
Founded in Baltimore, Maryland in 2018, OncoSTING develops innovative therapies for bladder cancer. The company combines the potency of standard BCG immunotherapy with long-lived delivery of potent STING agonists to enhance immune response and improve safety profiles.
Jelikalite develops medical equipment for children with autism spectrum disorders, focusing on non-invasive approaches to support brain health. The company has created a therapeutic wearable device that combines near-infrared light, sensors, and a machine-learning personalization system to deliver non-invasive brain stimulation. Designed for home-based use without a therapist's physical presence, the device seeks to improve communication, responsiveness, and social interaction in children with autism.
Oxalo Therapeutics
Grant in 2022
Oxalo Therapeutics develops therapies to treat rare kidney diseases and prevent recurrent oxalate-related stones, focusing on primary hyperoxaluria and other oxalate pathologies. It leverages microbiome science, translational research, and early-stage technology to create a gut-derived therapy that safely removes oxalate from the body, reducing stone recurrence and related renal complications.
AirOmatix is a biotechnology company focused on innovating methods for oxygen concentration, storage, and delivery across various sectors, including healthcare, athletics, and food storage. The company is commercializing a novel, patent-pending technology that utilizes photochemical reactions to concentrate and remove oxygen from ambient air. This process achieves higher purity levels above 99% and greater flow rates compared to traditional pressure swing adsorption devices. AirOmatix is developing high-flow oxygen concentrators that can produce continuous flow rates exceeding 6.0 L/min, while also creating ultra-portable devices that are comparable in size to a coffee mug. For industrial applications, the technology aims to replace the need for truckload deliveries of liquid oxygen by providing on-site generators capable of producing multiple tons of high-purity liquid oxygen daily.
AccuBreath specializes in developing innovative respiratory care solutions. Their flagship product is an affordable, high-end, ultraportable ventilator designed for gentle and portable respiratory support during medical procedures.
HairDays is an AI-powered health data company that has developed a unique hair intelligence platform aimed at simplifying hair classification, care, and product selection. This innovative platform provides personalized recommendations for maintaining healthy hair by curating relevant content and facilitating the discovery and purchase of hair care products. Users can track their hair growth progress and improve their hair conditions through tailored insights, making HairDays a valuable resource for individuals seeking to enhance their hair care routines.
Levisonics manufactures blood coagulation instruments for non-contact analysis of blood coagulation and fluid quality control. Its technology enables risk assessments for bleeding and thrombosis, and real-time monitoring of liquid goods' quality during production.
Intelligent Medicine
Grant in 2022
Intelligent Medicine is a company that specializes in software and simulation services focused on the medical, artificial intelligence, and virtual reality sectors. The company has developed a simulation platform aimed at reducing the probability of infectious spread and user congestion in various environments. This platform enables architects and facility stakeholders to identify risks, optimize building designs, and redesign protocols to enhance safety outcomes. By testing multiple design scenarios and behaviors, Intelligent Medicine provides quick feedback that assists in planning effective safety policies and design actions, ultimately improving facility infrastructure and user experiences.
Dynocardia is a biomedical device company developing wearable, non-invasive blood pressure monitoring technology. Its ViTrack wrist-wearable device provides direct, beat-by-beat measurement of blood pressure and tracks heart rate, respiration, and rhythm with accuracy comparable to intra-arterial lines. The platform uses a wearable optomechanical sensor to enable continuous, mobile monitoring of cardiovascular parameters. Founded in 2018, the company is headquartered in Massachusetts and focuses on meeting critical clinical needs with portable monitoring solutions.
PediaMetrix is a pediatric health technology company that develops AI-powered cranial measurement and monitoring tools to detect and manage head shape abnormalities in newborns. Its SoftSpot platform provides quantitative cranial measurements via a smartphone app, enabling at-home and in-office use, and offers data-driven guidance and repositioning instructions for parents. The system also gives pediatricians access to simplified analysis and data from the app to support clinical decisions, and is supported by FDA-cleared digital tools for pediatric head assessment. Founded in 2018, the company is based in Rockville, Maryland, and leverages computer vision and artificial intelligence to lower healthcare costs and improve outcomes in pediatric head care.
CereVu Medical
Grant in 2021
CereVu Medical specializes in developing advanced medical devices. Their primary product is a wearable, single-use forehead patch connected to a reusable console, designed to monitor and analyze cerebral hemodynamics in real-time. This system employs proprietary algorithms to provide continuous pain score assessments, enabling healthcare professionals to tailor treatments based on individual patient needs.
Nanopath is a molecular diagnostics company that develops innovative platforms for rapid disease diagnosis. Its technology enables point-of-care testing, eliminating the need for nucleic acid amplification and supporting multiplexed detection. This allows patients and healthcare providers to access accurate diagnostic results within standard office visits, improving healthcare outcomes.
Averto Medical
Grant in 2021
Averto Medical specializes in the manufacture of medical devices designed to improve outcomes for patients with gastrointestinal diseases. Their innovative solutions aim to facilitate minimally invasive colorectal tumor removal and other gastrointestinal surgeries, enabling healthcare professionals to provide optimal care.
Nasus Medical
Grant in 2021
Nasus Medical specializes in developing innovative, non-invasive drug-delivery devices aimed at improving the treatment of chronic sinusitis. Their flagship product enables patients to self-administer medication rapidly and conveniently, reducing the need for oral medications with systemic side effects, injections by healthcare professionals, or costly surgical procedures. This approach aims to enhance patient comfort, convenience, and outcomes while lowering overall healthcare costs.
EchoWear is a company focused on enhancing healthcare access through its innovative smartwatch-based system. This system facilitates meaningful interactions between patients and care teams, promoting the development of actionable digital health services. By prioritizing age-friendly health technologies, EchoWear aims to improve the overall healthcare experience for users, ensuring that they can effectively engage with their health management through digital solutions.
Pragma Health
Grant in 2021
Pragma Health provides digital healthcare services. They permit users to perform different tests for cardiovascular, hematology, infectious diseases, and others in the privacy of their home and provide accurate, immediate results, enabling them to get a convenient, cost-effective, and accurate healthcare testing process.
Compact Medical Solutions
Grant in 2021
Compact Medical Solutions develops a medical bag-valve-mask used to assist patients experiencing emergency breathing issues. The ultra-compact device aims to improve resuscitation by preventing hyperventilation and enabling medical personnel to safely ventilate patients whose breathing is compromised. Founded in 2016 and based in Indianapolis, Indiana, the company focuses on creating portable respiratory support tools for first responders and healthcare providers.
Kodikaz Therapeutic Solutions
Grant in 2021
Kodikaz Therapeutic Solutions develops a genomic transfer delivery platform for RNA and DNA delivery vectors, aiming to move beyond conventional cancer therapies toward durable cures through targeted gene transfer. Its Zip-Code technology is a cell-specific delivery system derived from an endogenous human mechanism, designed to avoid the challenges of viral delivery and to be applicable across multiple cell types. The company translates cell-recognition and genomic integration mechanisms identified in human cancers into practical therapies, generating both in vitro and in vivo data in oncology to support the development of cell-targeted gene transfer technologies into curative treatments. Applications include cancers such as pancreatic cancer, multiple myeloma, and colorectal cancer, and the platform supports collaborations to help clients develop cell-specific gene transfer approaches.
Innsightful develops wearable devices that monitor and detect anxiety and stress symptoms using AI and machine learning. Their solution integrates biometrics for early detection and provides access to therapists for personalized recommendations, empowering users to understand and manage their mental health.
SingletO2 Therapeutics
Grant in 2021
SingletO2 Therapeutics, established in 2015 and based in New Providence, New Jersey, focuses on developing innovative treatments for periodontal disease. The company leverages the potent bacteria-killing properties of singlet oxygen to create therapies that can address advanced stages of the disease without the need for surgical intervention.
NeuroTechR3 is a biomedical device and digital health start-up focused on developing affordable rehabilitation technologies aimed at enhancing upper extremity function in individuals affected by brain injuries, such as stroke and cerebral palsy. The company's flagship innovation, R3THATM, leverages machine learning-driven cloud technology and exergames tailored to promote neuroplasticity, incorporating motion tracking, analytics, and real-time biofeedback. Founded in 2020 by four women as a spinout from the New Jersey Institute of Technology and Rutgers School of Health Professions, NeuroTechR3 is committed to transforming the rehabilitation industry into a proactive, patient-centered process. The company operates from locations in Newark, NJ, and Philadelphia, PA, and has established partnerships with rehabilitation hospitals, outpatient centers, and therapists. With its expertise in biomedical engineering and computer science, the team is equipped to adapt swiftly to industry needs, aiming to provide sustainable and accessible rehabilitation solutions for individuals with various impairments. Through the advancement of rehabilitation devices and machine learning technology, NeuroTechR3 seeks to make a significant positive impact on global health outcomes.
EnVision Endoscopy
Grant in 2021
EnVision Endoscopy specializes in developing innovative medical devices aimed at enhancing endoscopic surgical procedures. Their flagship product is an image-guided suturing system designed to be attached to flexible endoscopes, making it accessible to a wide range of gastroenterologists and surgeons. This biodegradable, single-use device facilitates easier completion of procedures by enabling tissue approximation during surgeries. The company's solutions are intended to reduce procedure time and mortality rates in hospitals, addressing critical clinical needs for policymakers, insurers, clinicians, and patients alike.
Avior Bio is a clinical-stage pharmaceutical company focused on developing innovative therapies for distressed neurological conditions and associated symptoms, including pruritus resulting from liver disease. The company utilizes its proprietary Speedit™ Transmucosal Film Technology, which enhances drug delivery by avoiding first-pass metabolism and significantly reducing glucuronide metabolites excreted by the kidneys. This technology aims to provide effective relief from various conditions, such as insomnia, anxiety, depression, and skin excoriation, thus offering improved efficacy and safety for patients. With a strong management team, an experienced advisory board, and a dedicated group of scientists and clinicians, Avior Bio is well-positioned to advance its mission of delivering high-value therapeutic solutions.
Desert Valley Tech
Grant in 2021
Founded in 2018, Desert Valley Tech specializes in developing advanced cold chain storage systems. These systems maintain precise temperatures for blood, pharmaceuticals, biologics, organs, and other sensitive items, optimizing power consumption and offering customizable modular storage solutions. This enables improved patient outcomes, particularly in challenging medical environments.
Access Airways
Grant in 2021
Access Airways is a company that specializes in the development of innovative intubation-delivering devices designed to improve the safety and efficiency of intubation procedures. Their flagship product is a minimally invasive articulating intubation stylet that enhances access to difficult airways, thereby aiming to upscale the standard of care during patient intubation. The device features intuitive capabilities that allow clinicians to perform quicker and less harmful procedures, significantly reducing the time required for intubation and minimizing the risk of failed attempts. Its design enables effortless control and articulation of the tip, allowing for enhanced navigation in challenging airway situations, ultimately benefiting both caregivers and patients.
Grapevine Health
Grant in 2021
Grapevine Health is a data-driven health media company focused on delivering health information to underserved communities. By utilizing technical expertise and trusted messengers, the company aims to democratize health information and empower patients through empathetic storytelling. Grapevine Health also offers health literacy services that assist health systems, insurers, and medical providers in enhancing community outreach and engagement. Their strategies include designing and delivering culturally appropriate communications and marketing materials, enabling clients to provide health information that is relatable and easily understandable. Through these efforts, Grapevine Health seeks to promote health literacy and sustain healthy behaviors within the communities it serves.
NeuroTechR3 is a biomedical device and digital health start-up focused on developing affordable rehabilitation technologies aimed at enhancing upper extremity function in individuals affected by brain injuries, such as stroke and cerebral palsy. The company's flagship innovation, R3THATM, leverages machine learning-driven cloud technology and exergames tailored to promote neuroplasticity, incorporating motion tracking, analytics, and real-time biofeedback. Founded in 2020 by four women as a spinout from the New Jersey Institute of Technology and Rutgers School of Health Professions, NeuroTechR3 is committed to transforming the rehabilitation industry into a proactive, patient-centered process. The company operates from locations in Newark, NJ, and Philadelphia, PA, and has established partnerships with rehabilitation hospitals, outpatient centers, and therapists. With its expertise in biomedical engineering and computer science, the team is equipped to adapt swiftly to industry needs, aiming to provide sustainable and accessible rehabilitation solutions for individuals with various impairments. Through the advancement of rehabilitation devices and machine learning technology, NeuroTechR3 seeks to make a significant positive impact on global health outcomes.
PediaMetrix
Seed Round in 2021
PediaMetrix is a pediatric health technology company that develops AI-powered cranial measurement and monitoring tools to detect and manage head shape abnormalities in newborns. Its SoftSpot platform provides quantitative cranial measurements via a smartphone app, enabling at-home and in-office use, and offers data-driven guidance and repositioning instructions for parents. The system also gives pediatricians access to simplified analysis and data from the app to support clinical decisions, and is supported by FDA-cleared digital tools for pediatric head assessment. Founded in 2018, the company is based in Rockville, Maryland, and leverages computer vision and artificial intelligence to lower healthcare costs and improve outcomes in pediatric head care.
Florica Therapeutics
Grant in 2021
Florica Therapeutics is a biotechnology company founded in 2019 and based in Livermore, California. The company specializes in the development of exosome-based therapeutics aimed at extending lifespan and preventing diseases associated with aging. Florica's innovative therapeutics focus on delivering drugs to the brain and provide alternatives for treatment of life-altering conditions such as leukemia and Tay-Sachs disease. By leveraging exosome technology, the company aims to offer health institutions access to novel treatments that enhance patient longevity and quality of life.
Founded in 2019, Oncospace is a medical technology company specializing in radiation oncology. It develops an AI-based platform designed to personalize patient treatment plans, minimize side effects, and maintain quality of life.
Proov is a company that specializes in developing rapid response urine test strips for measuring progesterone, a hormone essential for confirming ovulation and supporting conception. Unlike traditional in-home tests that primarily measure hormones like LH, FSH, and estrogen during the early menstrual cycle, Proov's tests provide a more comprehensive assessment by specifically tracking progesterone levels. This capability allows women to not only predict ovulation but also to identify potential hormonal imbalances that may contribute to infertility or miscarriage. By enabling women to monitor their hormonal health at home, Proov offers a cost-effective alternative to fertility clinics and IVF treatments, empowering them to take control of their reproductive health.
GRI Bio is a development-stage biotechnology company focused on discovering and developing therapies that modulate Natural Killer T (NKT) cell activity to treat inflammatory, autoimmune, and fibrotic diseases, including liver disease. Based in La Jolla, California, the company develops cell- and molecule-based approaches to regulate NKT cell function and restore immune homeostasis, with programs such as GRI-0621, an oral agent that inhibits type 1 NKT cell activity, and GRI-0803, a novel oral agonist targeting type 2 NKT cells.
iReprogram is a cell regeneration laboratory based in Ann Arbor, Michigan, established in 2017. The company focuses on advancing personalized medicine through innovative cell reprogramming technology. By utilizing a high-fidelity prototype computational tool, iReprogram generates transcription factor recipes that facilitate cellular trans-differentiation, particularly for cancer treatment. This technology aims to enhance the effectiveness of cancer therapies, ultimately allowing patients to benefit from more tailored and effective treatment options.
Lasarrus is a medical device company founded in 2013 and headquartered in Baltimore, Maryland. The company specializes in developing wearable devices aimed at enhancing the physical therapy experience for patients, particularly those with chronic obstructive pulmonary disease. Lasarrus's innovative device facilitates remote monitoring and telemedicine by capturing physiological and range-of-motion data from various points on the body. This technology provides patients with an affordable, comfortable, and non-invasive means to track their health routines and accelerate their recovery process.
TEGA Therapeutics
Grant in 2020
TEGA Therapeutics develops glycoscience-based technologies to treat life-threatening diseases. It focuses on glycan science to enhance delivery of enzyme replacement therapies to the brain for lysosomal storage disorders and on producing recombinant heparan sulfate and heparin. The company aims to overcome the blood-brain barrier to enable treatments for unmet medical needs and is based in La Jolla, California.
Plexision develops cellular biomarkers and personalized diagnostic tests for immunological disorders and solid organ transplantation. Its Pleximmune blood test predicts transplant rejection by measuring antigen-specific white blood cells, supported by patent-pending technology. The company operates a CLIA-certified central laboratory in Pittsburgh providing testing services for transplant recipients and drug developers. Its platform enables assessment of disease risk, prediction of drug efficacy for individual patients, and guidance on dosing for novel immunological therapies, with capabilities including rapid six-hour panels for conditions such as CMV infection and transplant rejection, and a focus on pediatric liver and intestine transplant patients.
Jupiter Therapeutics
Grant in 2020
Jupiter Therapeutics is a biotechnology company specializing in the development of cell-membrane-based therapeutics. It employs cell engineering techniques to create customized vesicles aimed at advancing immuno-oncology and gene therapy. By leveraging a synthetic biology approach, Jupiter Therapeutics facilitates the rapid design and synthesis of a diverse pipeline of therapeutic assets that address critical areas such as cancer and autoimmunity. The company allows medical researchers to utilize insights from cell-membrane studies to enhance the effectiveness of CAR T-cells and bi-specific antibodies, thereby contributing to innovative treatments in the biotherapeutics field.
Travera, LLC is a biotechnology company based in Cambridge, Massachusetts, founded in 2017. It specializes in cancer therapy guidance through its innovative measurement technology, utilizing the Suspended Microchannel Resonator (SMR). This advanced device functions as an extremely sensitive scale that can detect minute changes in the weight of individual cancer cells, specifically measuring the Mass Accumulation Rate (MAR) biomarker. By identifying rapid weight changes in response to cancer drugs, Travera enables oncologists to make informed decisions about which therapies to prescribe, based on the actual responses of patients' tumor cells. The technology is designed to differentiate between natural cell death and drug-induced cell death, providing timely and accurate insights that are critical for effective cancer treatment.
CoreMap, Inc. is a medical technology company based in Winooski, Vermont, focused on developing advanced diagnostic solutions for electrophysiologists treating atrial fibrillation. Incorporated in 2016, the company offers a micro-electrode solution that allows for sequential mapping of tissue properties, addressing significant challenges in the treatment of atrial fibrillation, such as poor spatial resolution and inadequate sample density. Additionally, CoreMap's ultra-high resolution electrodes provide detailed insights into cardiac activation, even during episodes of fibrillation. By enhancing the diagnostic capabilities of electrophysiologists, CoreMap aims to improve patient outcomes in the management of this complex condition.
Rizlab Health
Grant in 2020
Founded in 2018, Rizlab Health specializes in developing compact blood diagnostic devices. Their flagship product is CytoTracker, a pocket-sized, wireless analyzer powered by artificial intelligence, designed to deliver rapid and affordable white blood cell count analysis.
CereVu Medical
Grant in 2020
CereVu Medical specializes in developing advanced medical devices. Their primary product is a wearable, single-use forehead patch connected to a reusable console, designed to monitor and analyze cerebral hemodynamics in real-time. This system employs proprietary algorithms to provide continuous pain score assessments, enabling healthcare professionals to tailor treatments based on individual patient needs.
EnVision Endoscopy
Grant in 2020
EnVision Endoscopy specializes in developing innovative medical devices aimed at enhancing endoscopic surgical procedures. Their flagship product is an image-guided suturing system designed to be attached to flexible endoscopes, making it accessible to a wide range of gastroenterologists and surgeons. This biodegradable, single-use device facilitates easier completion of procedures by enabling tissue approximation during surgeries. The company's solutions are intended to reduce procedure time and mortality rates in hospitals, addressing critical clinical needs for policymakers, insurers, clinicians, and patients alike.
Manus Robotics
Grant in 2020
Manus Robotics is a developer of advanced health and wellness devices aimed at promoting independent and healthy living. The company specializes in a wearable robot that offers intelligent daily living assistance to individuals with disabilities. In addition to facilitating daily activities, this device collects and analyzes muscle data from patients, which is crucial for rehabilitation. By focusing on these innovative solutions, Manus Robotics helps individuals with disabilities improve their quality of life and regain their independence.
Biocogniv develops AI-powered diagnostic tools for hospitals, delivering real-time clinical intelligence by integrating with electronic health records. Its platform analyzes standard blood tests and other data to screen patients for COVID-19 and to predict sepsis-related in-hospital mortality and ICU admission at emergency department presentations, enabling non-invasive, data-driven decision making. The solution plugs into existing EHR workflows to improve quality, lower costs, and expand access to care. The company was founded in 2019 and is based in Burlington, Vermont.
3i DIAGNOSTICS
Grant in 2020
3i DIAGNOSTICS provides technology that enables physicians to identify infectious microbes in less than minutes while leaving them intact for further testing. They help to make more informed infection-treatment decisions while practising antibiotic stewardship.
Unlocked Labs
Grant in 2020
Unlocked Labs develops targeted probiotics designed to manage specific health conditions. Their first product focuses on reducing kidney stone risk by digesting a stone-forming compound found in healthy foods like leafy vegetables.
Hubly Surgical
Non Equity Assistance in 2020
Hubly Surgical Inc., established in 2018 with headquarters in San Francisco and a satellite office in Chicago, specializes in developing innovative neurosurgical devices aimed at enhancing patient outcomes and safety. The company's flagship product is an integrated electric drill system designed to replace traditional free-hand cranks, thereby reducing the risk of lethal complications during surgical procedures. Hubly Surgical's mission is to make its safety technology the standard for all medical drilling across various settings, including underserved areas, with a focus on improving patient care and quality of life.
InContext is a developer of an innovative healthcare platform that focuses on enhancing clinical decision support and quality management. The company's technology integrates seamlessly with electronic medical record systems, alleviating the burden of data entry and transformation tasks that often overwhelm healthcare providers. By automating these processes, InContext enables physicians to concentrate on patient care. Additionally, the platform features tools that capture reimbursement opportunities and assist users in actively managing care quality and compliance for both individuals and teams. This approach aims to streamline clinical workflows and improve overall efficiency in healthcare settings.
Blossom Surgical
Grant in 2020
Blossom Surgical specializes in the development of medical devices aimed at enhancing Minimally Invasive Surgery (MIS). The company focuses on creating power morcellators equipped with containment systems, which facilitate the isolation, severing, and removal of large tissue specimens during laparoscopic procedures. By employing a direct entry puncture technique through a small umbilical incision, measuring just 1.8 cm, Blossom Surgical's devices aim to minimize the risks associated with traditional surgical methods, including hematomas, infections, and hernias. Through its innovative approach, the company provides medical professionals with more effective tools for performing contained morcellation, ultimately improving patient outcomes in surgical settings.
AxonDx is a biotechnology company specializing in the detection of circulating tumor cells (CTCs) in blood samples, which serve as critical indicators of the presence of solid tumors and potential metastases. The company has developed the nCYTE™ technology, a device that rapidly scans un-enriched blood samples, identifying all classes of CTCs within minutes. This innovative approach not only enhances the speed and accuracy of CTC detection but also provides morphological and molecular characterization of the identified cells. By enabling earlier self-diagnosis of cancer and facilitating personalized medical treatment, AxonDx aims to transform cancer management. The company operates a "razor and blade" business model, selling nCYTE™ instruments and associated diagnostic kits for use in clinical settings, making advanced cancer detection accessible and cost-effective at the point of care.
LEAH Laboratories specializes in developing innovative gene-editing technologies aimed at treating cancer in dogs, particularly B-cell lymphoma. The company utilizes precision gene editing to reprogram T immune cells with Chimeric Antigen Receptors (CAR), creating CAR T cells that can specifically target and eliminate cancerous cells while minimizing off-target effects commonly associated with traditional chemotherapy. By harnessing the natural capabilities of the canine immune system, LEAH Laboratories provides a novel approach to cancer treatment, offering hope to pet owners and veterinarians in their fight against this challenging disease. Based in the United States, LEAH Labs is committed to advancing medical therapies for canine health.
Iterex is dedicated to revolutionizing at-home care of chronic illnesses through early, cost effective, personalized mobile digital health applications.
Globe Biomedical
Grant in 2020
Globe Biomedical, established in 2017 and based in Riverside, California, specializes in developing wearable technology for glaucoma patients. The company's core product is an ocular healthcare technology, discreetly integrated into stylish eyeglass frames, which wirelessly transmits data on eye health, enabling patients and healthcare providers to monitor and manage glaucoma more effectively.
Averto Medical
Grant in 2020
Averto Medical specializes in the manufacture of medical devices designed to improve outcomes for patients with gastrointestinal diseases. Their innovative solutions aim to facilitate minimally invasive colorectal tumor removal and other gastrointestinal surgeries, enabling healthcare professionals to provide optimal care.
AccuBreath specializes in developing innovative respiratory care solutions. Their flagship product is an affordable, high-end, ultraportable ventilator designed for gentle and portable respiratory support during medical procedures.
Flaskworks is a company focused on enhancing the production of immunotherapeutics and dendritic cell-based vaccines. It develops innovative technologies for manufacturing dendritic cells and creates modular, closed, and disposable systems designed to overcome the challenges associated with therapy bottlenecks. By addressing these critical issues, Flaskworks aims to enable physicians to treat patients with greater success and efficiency, particularly in the context of cancer and other diseases.
HX Innovations
Grant in 2019
HX Innovations, Inc. is a Delaware-based company specializing in human performance and biomechanics testing and technology. The company has developed patent-pending GenL Movement Technology, which offers data-driven neuroergonomic and biomechanic solutions. This technology is designed to measure muscle activity and physical performance while assessing knee injury risk. By providing movement analytics, HX Innovations enables trainers and coaches to evaluate player performance, rank athletes, and formulate strength and conditioning strategies, as well as return-to-play protocols. This comprehensive approach helps clients develop health and performance programs that optimize human capabilities.
TAO Connect, Inc. is a company that develops and delivers an online treatment program targeting various mental health issues, including generalized anxiety, social anxiety, performance anxiety, and substance abuse recovery. By utilizing a cognitive behavioral treatment module, patients can actively engage in behavioral change while clinicians monitor progress. This module includes educational resources, video conferencing, text messaging, push notifications to encourage engagement, and daily practice assignments through smartphone applications. The company aims to make mental health services more affordable and accessible, significantly benefiting those who have faced barriers to treatment. Its services cater to a wide range of institutions, such as college counseling centers, wellness centers, employee assistance programs, outpatient mental health clinics, and private practitioners. Founded in 2014 and headquartered in Saint Petersburg, Florida, TAO Connect is dedicated to reducing mental health disparities and enhancing the quality of care available to individuals in need.
PediaMetrix
Pre Seed Round in 2019
PediaMetrix is a pediatric health technology company that develops AI-powered cranial measurement and monitoring tools to detect and manage head shape abnormalities in newborns. Its SoftSpot platform provides quantitative cranial measurements via a smartphone app, enabling at-home and in-office use, and offers data-driven guidance and repositioning instructions for parents. The system also gives pediatricians access to simplified analysis and data from the app to support clinical decisions, and is supported by FDA-cleared digital tools for pediatric head assessment. Founded in 2018, the company is based in Rockville, Maryland, and leverages computer vision and artificial intelligence to lower healthcare costs and improve outcomes in pediatric head care.
Lasarrus is a medical device company founded in 2013 and headquartered in Baltimore, Maryland. The company specializes in developing wearable devices aimed at enhancing the physical therapy experience for patients, particularly those with chronic obstructive pulmonary disease. Lasarrus's innovative device facilitates remote monitoring and telemedicine by capturing physiological and range-of-motion data from various points on the body. This technology provides patients with an affordable, comfortable, and non-invasive means to track their health routines and accelerate their recovery process.
Oxalo Therapeutics
Grant in 2019
Oxalo Therapeutics develops therapies to treat rare kidney diseases and prevent recurrent oxalate-related stones, focusing on primary hyperoxaluria and other oxalate pathologies. It leverages microbiome science, translational research, and early-stage technology to create a gut-derived therapy that safely removes oxalate from the body, reducing stone recurrence and related renal complications.
Founded in 2019, Oncospace is a medical technology company specializing in radiation oncology. It develops an AI-based platform designed to personalize patient treatment plans, minimize side effects, and maintain quality of life.
EnVision Endoscopy
Grant in 2019
EnVision Endoscopy specializes in developing innovative medical devices aimed at enhancing endoscopic surgical procedures. Their flagship product is an image-guided suturing system designed to be attached to flexible endoscopes, making it accessible to a wide range of gastroenterologists and surgeons. This biodegradable, single-use device facilitates easier completion of procedures by enabling tissue approximation during surgeries. The company's solutions are intended to reduce procedure time and mortality rates in hospitals, addressing critical clinical needs for policymakers, insurers, clinicians, and patients alike.
Teaching It Right
Grant in 2019
Teaching It Right is an educational curriculum development company specializing in services for children diagnosed with autism spectrum disorder. The company creates supplementary materials and curricula tailored for individuals, educational institutions, and related professionals. Their offerings include an integrated mobile application designed to teach social skills and a multi-sensory therapy program aimed at improving eye contact. These resources help children become more engaged in society, prepare for self-sufficiency as adults, and enhance their employment prospects.
PediaMetrix
Pre Seed Round in 2019
PediaMetrix is a pediatric health technology company that develops AI-powered cranial measurement and monitoring tools to detect and manage head shape abnormalities in newborns. Its SoftSpot platform provides quantitative cranial measurements via a smartphone app, enabling at-home and in-office use, and offers data-driven guidance and repositioning instructions for parents. The system also gives pediatricians access to simplified analysis and data from the app to support clinical decisions, and is supported by FDA-cleared digital tools for pediatric head assessment. Founded in 2018, the company is based in Rockville, Maryland, and leverages computer vision and artificial intelligence to lower healthcare costs and improve outcomes in pediatric head care.
Macomb Community College
Grant in 2019
Founded in Warren, Michigan, Macomb Community College offers a wide range of associate's transfer programs, bachelor's degrees, graduate studies, and career training courses across over 200 fields. It fosters an active student life with various clubs, events, and multicultural initiatives. The college provides pre-college programs, professional education, customized workforce training, and cultural programs. New students must complete admissions application, placement testing, orientation, and course registration to enroll. Scholarships and financial aid options are available for eligible students.
Levisonics manufactures blood coagulation instruments for non-contact analysis of blood coagulation and fluid quality control. Its technology enables risk assessments for bleeding and thrombosis, and real-time monitoring of liquid goods' quality during production.
Travera, LLC is a biotechnology company based in Cambridge, Massachusetts, founded in 2017. It specializes in cancer therapy guidance through its innovative measurement technology, utilizing the Suspended Microchannel Resonator (SMR). This advanced device functions as an extremely sensitive scale that can detect minute changes in the weight of individual cancer cells, specifically measuring the Mass Accumulation Rate (MAR) biomarker. By identifying rapid weight changes in response to cancer drugs, Travera enables oncologists to make informed decisions about which therapies to prescribe, based on the actual responses of patients' tumor cells. The technology is designed to differentiate between natural cell death and drug-induced cell death, providing timely and accurate insights that are critical for effective cancer treatment.
Globe Biomedical
Grant in 2019
Globe Biomedical, established in 2017 and based in Riverside, California, specializes in developing wearable technology for glaucoma patients. The company's core product is an ocular healthcare technology, discreetly integrated into stylish eyeglass frames, which wirelessly transmits data on eye health, enabling patients and healthcare providers to monitor and manage glaucoma more effectively.
TEGA Therapeutics
Grant in 2019
TEGA Therapeutics develops glycoscience-based technologies to treat life-threatening diseases. It focuses on glycan science to enhance delivery of enzyme replacement therapies to the brain for lysosomal storage disorders and on producing recombinant heparan sulfate and heparin. The company aims to overcome the blood-brain barrier to enable treatments for unmet medical needs and is based in La Jolla, California.
Rumi Scientific
Grant in 2019
Rumi Scientific is a biotechnology company focused on accelerating the discovery of therapeutics for central nervous system and genetic brain disorders. It has developed an AI-enhanced organoid-like platform that replicates human brain development in vitro, using gene-edited disease models and multicellular self-organization to create defined diseased embryonic tissues. The platform enables high-throughput drug screening and candidate prioritization to identify effective treatments for neurodegenerative and other genetic conditions. By integrating synthetic human embryology with data-driven analysis, the company aims to streamline preclinical drug development and expand options for disorders that currently lack cures.
Cybele Microbiome
Grant in 2019
Cybele Microbiome is a biotechnology company focused on enhancing skin health through precision control of the microbiome. The company utilizes a proprietary AI platform that integrates machine learning with advanced biotechnology and unique data sources to identify natural prebiotics. These prebiotics are designed to nourish the microbiome, leading to the development of customized skincare products. By employing genetic sequencing methods and sustainable nutrient sources, Cybele Microbiome aims to strengthen the skin's natural barrier and promote overall health and longevity. The innovative approach combines artificial intelligence with microbiome science to revolutionize skincare, enabling consumers to maintain the integrity of their skin through effective and conscientious skincare solutions.
Iterex is dedicated to revolutionizing at-home care of chronic illnesses through early, cost effective, personalized mobile digital health applications.
Flaskworks is a company focused on enhancing the production of immunotherapeutics and dendritic cell-based vaccines. It develops innovative technologies for manufacturing dendritic cells and creates modular, closed, and disposable systems designed to overcome the challenges associated with therapy bottlenecks. By addressing these critical issues, Flaskworks aims to enable physicians to treat patients with greater success and efficiency, particularly in the context of cancer and other diseases.
3i DIAGNOSTICS
Grant in 2018
3i DIAGNOSTICS provides technology that enables physicians to identify infectious microbes in less than minutes while leaving them intact for further testing. They help to make more informed infection-treatment decisions while practising antibiotic stewardship.
MediCool Technologies
Grant in 2018
MediCool Technologies specializes in developing innovative, painless solutions for treating dangerous cardiac arrhythmias and other disorders. Its primary focus is on atrial fibrillation and common arrhythmias, enabling patients to receive treatment without discomfort.
Radial Analytics
Grant in 2018
Radial Analytics focuses on addressing significant data challenges in healthcare through its innovative cloud-based planning system. The company's primary product is a decision support solution designed for hospital case managers and discharge planners, enabling them to identify the most appropriate post-acute care facilities for patients. This system utilizes an evidence-driven approach, taking into account each patient's unique clinical, functional, and behavioral needs. By capturing and processing extensive real-time patient data, Radial Analytics helps hospitals optimize the quality of care while reducing post-acute costs for shared-risk patients. The company is partially supported by the National Science Foundation, which aids in the development of technology aimed at creating positive societal and economic impacts.
MyHomecareBiz
Grant in 2017
MyHomecareBiz is a company specializing in the development of intuitive home health software aimed at enhancing the efficiency of home care management. Since its inception in 1998, it has focused on automating key aspects such as patient care, billing, scheduling, and physician orders. The software solutions are designed, developed, and tested by a team of experienced home health care nurses and therapists, ensuring they meet the practical needs of the industry. Key offerings include SmartDX, a mobile application that tracks value-based purchasing outcomes and facilitates real-time updates to care plans, and TurboClaim, an efficient billing system that automates the claim submission process and payment posting. This allows home health care professionals to concentrate on patient care rather than administrative tasks.
Micro-Leads is a medical technology company developing neuromodulation and bioelectronic therapies. It is building a wireless implantable neuromodulation device capable of arbitrary bi-phasic pulses and kilohertz blocking patterns. The platform supports wireless programming of stimulation patterns through a browser-based interface and powers subcutaneous peripheral nerve stimulators, with features such as adjustable amplitudes and wireless charging, including accessories like backpacks and portable stimulators. The technology aims to enable spinal cord stimulation therapies for back pain and related disorders, with applications in both clinical and animal research settings.
Clerio Vision
Grant in 2017
Clerio Vision is a medical device company focused on refractive and ophthalmic technologies, including contact lenses and intraocular lenses. The company develops and commercializes next-generation products designed to address safety and performance concerns associated with current refractive procedures. Its laser-induced refractive index correction technology enables modification of the corneal refractive index to improve vision and treatment outcomes, offering physicians potential new options for vision correction. Founded in 2014, Clerio Vision is headquartered in Rochester, New York.
OESH Shoes specializes in footwear designed based on peer-reviewed medical science to minimize stress and strain on women's muscles, tendons, ligaments, and joints. They offer a range of styles for various activities, promoting optimal comfort and health.
DFusion is a science-based behavioral health research and development company focused on promoting behavior change to improve health outcomes. The company utilizes evidence-based behavior change models and learning theories to create innovative technology solutions aimed at health, prevention, and adherence. DFusion develops smartphone, tablet, and web applications that enhance user experience while facilitating healthier behaviors. Its team comprises scientists and innovators dedicated to challenging conventional approaches and making a positive impact on health and well-being across various life stages. Based in Scotts Valley and Oakland, California, DFusion also offers consultation services and professional development opportunities in health and education, including the development, testing, evaluation, and dissemination of systems that support the adoption of healthy behaviors.
Teaching It Right
Grant in 2017
Teaching It Right is an educational curriculum development company specializing in services for children diagnosed with autism spectrum disorder. The company creates supplementary materials and curricula tailored for individuals, educational institutions, and related professionals. Their offerings include an integrated mobile application designed to teach social skills and a multi-sensory therapy program aimed at improving eye contact. These resources help children become more engaged in society, prepare for self-sufficiency as adults, and enhance their employment prospects.
Shasqi is a biopharmaceutical company developing the CAPAC™ platform, which uses click chemistry to locally activate cancer treatments within tumors. This approach concentrates and activates prodrugs directly at the desired location, minimizing systemic exposure and toxicity.
MediCool Technologies
Grant in 2016
MediCool Technologies specializes in developing innovative, painless solutions for treating dangerous cardiac arrhythmias and other disorders. Its primary focus is on atrial fibrillation and common arrhythmias, enabling patients to receive treatment without discomfort.
Workit Health
Grant in 2016
Workit Health provides online therapeutic content and professional counseling services for substance use recovery. It offers Workit, an interactive platform for individuals seeking to reduce or quit alcohol consumption, providing discreet access to on-demand medical and psychosocial support.
TAO Connect, Inc. is a company that develops and delivers an online treatment program targeting various mental health issues, including generalized anxiety, social anxiety, performance anxiety, and substance abuse recovery. By utilizing a cognitive behavioral treatment module, patients can actively engage in behavioral change while clinicians monitor progress. This module includes educational resources, video conferencing, text messaging, push notifications to encourage engagement, and daily practice assignments through smartphone applications. The company aims to make mental health services more affordable and accessible, significantly benefiting those who have faced barriers to treatment. Its services cater to a wide range of institutions, such as college counseling centers, wellness centers, employee assistance programs, outpatient mental health clinics, and private practitioners. Founded in 2014 and headquartered in Saint Petersburg, Florida, TAO Connect is dedicated to reducing mental health disparities and enhancing the quality of care available to individuals in need.
LightDeck Diagnostics
Grant in 2016
MBio Diagnostics, Inc., operating as LightDeck Diagnostics, specializes in developing rapid clinical diagnostics and sample testing products that provide immediate results for various diseases, including HIV, hepatitis, COVID-19, and influenza. The company offers innovative solutions such as the MBio multiplex analyzers and disposable cartridges, which are applicable in medical, veterinary, environmental, food, agricultural, and military sectors. Their flagship product, the LightDeck device, delivers lab-quality results within minutes, making it suitable for diverse settings, from emergency departments and nursing homes to pharmacies and workplaces. Additionally, MBio array systems enable the simultaneous measurement of multiple analytes from a single sample through multiplexed fluorescence immunoassays. Founded in 2009 and headquartered in Boulder, Colorado, MBio Diagnostics is committed to advancing point-of-care testing with its proprietary technology that combines advanced laser waveguides and novel materials.
Micro-Leads is a medical technology company developing neuromodulation and bioelectronic therapies. It is building a wireless implantable neuromodulation device capable of arbitrary bi-phasic pulses and kilohertz blocking patterns. The platform supports wireless programming of stimulation patterns through a browser-based interface and powers subcutaneous peripheral nerve stimulators, with features such as adjustable amplitudes and wireless charging, including accessories like backpacks and portable stimulators. The technology aims to enable spinal cord stimulation therapies for back pain and related disorders, with applications in both clinical and animal research settings.
Radial Analytics
Grant in 2016
Radial Analytics focuses on addressing significant data challenges in healthcare through its innovative cloud-based planning system. The company's primary product is a decision support solution designed for hospital case managers and discharge planners, enabling them to identify the most appropriate post-acute care facilities for patients. This system utilizes an evidence-driven approach, taking into account each patient's unique clinical, functional, and behavioral needs. By capturing and processing extensive real-time patient data, Radial Analytics helps hospitals optimize the quality of care while reducing post-acute costs for shared-risk patients. The company is partially supported by the National Science Foundation, which aids in the development of technology aimed at creating positive societal and economic impacts.
OESH Shoes specializes in footwear designed based on peer-reviewed medical science to minimize stress and strain on women's muscles, tendons, ligaments, and joints. They offer a range of styles for various activities, promoting optimal comfort and health.
iotaMotion, Inc. is a company focused on developing and manufacturing innovative cochlear ear implants to address hearing loss. Established in 2015 and based in Iowa City, Iowa, iotaMotion offers a robotic-assisted surgical system that standardizes the insertion of cochlear implant electrodes. This system is designed to enhance accessibility for both surgeons and patients, effectively reducing surgical variability by controlling the speed and acceleration of electrode insertion. By personalizing the insertion approach, iotaMotion enables healthcare professionals to deliver more precise and individualized cochlear intervention treatments, ultimately improving patient outcomes in hearing restoration.
TEGA Therapeutics
Grant in 2016
TEGA Therapeutics develops glycoscience-based technologies to treat life-threatening diseases. It focuses on glycan science to enhance delivery of enzyme replacement therapies to the brain for lysosomal storage disorders and on producing recombinant heparan sulfate and heparin. The company aims to overcome the blood-brain barrier to enable treatments for unmet medical needs and is based in La Jolla, California.
Clerio Vision
Grant in 2016
Clerio Vision is a medical device company focused on refractive and ophthalmic technologies, including contact lenses and intraocular lenses. The company develops and commercializes next-generation products designed to address safety and performance concerns associated with current refractive procedures. Its laser-induced refractive index correction technology enables modification of the corneal refractive index to improve vision and treatment outcomes, offering physicians potential new options for vision correction. Founded in 2014, Clerio Vision is headquartered in Rochester, New York.