Transparent Path
Grant in 2023
Transparent Path develops IoT-based logistics visibility technologies for perishable goods to reduce waste, cost, and risk in supply chains. It provides software and hardware that enable real-time location and condition monitoring through the Visibility Platform, using sensors to track shipments and alert partners when intervention is needed. The portfolio includes FreshScore, a predictive freshness algorithm, ProofScore, a data-transparency scoring system, and ProofTracker, a biodegradable sensor device. These tools support end-to-end visibility, improve decision making, and help buyers and sellers route the best products while reducing spoilage, waste, and disputes. The company serves food, pharmaceuticals, blood and plasma, transplant organs, and high-value hard goods, and works with consortiums to facilitate data sharing among supply chain partners. Strategic collaborations include Intel, T-Mobile, Duke University, and ReFED. Transparent Path has participated in accelerators and secured grants and angel investment to scale growth and feature development. The aim is to cut waste and environmental impact by keeping perishables out of landfills and strengthening trust across the supply chain.
OmniVis is a biotechnology company specializing in pathogen detection. It offers an integrated portable platform that rapidly and accurately identifies pathogens in various environments, reducing the need for labor-intensive lab testing.
Maine Shellfish Developers
Grant in 2022
Maine Shellfish Developers is a sustainable aquaculture company specializing in the production of oysters. They offer oyster seedlings and mature oysters, along with other related seafood products.
Canomiks offers a genomics, bioinformatics, and AI-driven platform that empowers companies in functional food, dietary supplements, and skincare sectors to create safe and effective products. Its long-term goal is to make 'food as medicine' a reality.
Secure Food Solutions
Grant in 2022
Secure Food Solutions Inc., established in 2014 and based in Martin, Tennessee, specializes in enhancing global food safety by developing advanced detection technologies for toxins, pathogens, and contaminants. The company's core offering is a patented hyperspectral imaging technology designed to swiftly identify corn contaminated with aflatoxin, aiming to improve food quality and safety worldwide.
Ummino offers precision fermentation technology for fortified food and beverage products. The company's technology unlocks rare compounds to transform commodity ingredients into high-value functional foods.
Levisonics manufactures blood coagulation instruments for non-contact analysis of blood coagulation and fluid quality control. Its technology enables risk assessments for bleeding and thrombosis, and real-time monitoring of liquid goods' quality during production.
Grain Weevil
Grant in 2022
Grain Weevil is a robot designed for agricultural use, specifically in grain bins. It levels fields, breaks crusts, conducts inspections, and feeds grain into extraction augers, thereby increasing management efficiency, reducing labor costs and spoilage, enhancing safety for farmers, and extending grain storage duration.
Pathotrak specializes in rapid food safety testing. Its patented technology reduces detection time of pathogens like Salmonella and E. coli from days to hours, meeting FDA and USDA regulations. This innovation helps minimize holding costs, enables swift recalls, and enhances overall food safety.
Ryp Labs is a company focused on developing and commercializing innovative technologies aimed at reducing food waste. It offers a range of products, including food-safe labels known as Shelf-Defense and stickers called StixFresh. These products are designed to be applied directly to fresh produce or its packaging, effectively prolonging shelf life and freshness by up to two times. By preventing spoilage and over-ripening, Ryp Labs' solutions provide a practical approach for clients to combat the global issue of food waste while extending the usability of their fresh products.
Farther Farms
Grant in 2021
Farther Farms is a food company focused on sustainable produce and innovative preservation. It provides locally sourced, organic, non-GMO fruits and vegetables and uses technology to improve environmental impact and flavor. The company also develops shelf-stable alternatives to traditionally frozen foods by applying high-pressure processing with dense carbon dioxide at moderate temperatures, a method designed to prevent spoilage without preservatives, chemicals, or genetic modification. This approach aims to reduce costs across the food system, including processing, distribution, and retail, while ensuring convenient, high-quality products for consumers.
Frost Defense
Grant in 2021
FrostDefense, founded in 2018 and based in Champaign, Illinois, specializes in developing innovative frost protection solutions. The company focuses on creating environmentally friendly biofertilizers and patented sprayable compounds designed to combat early spring frost, particularly in vineyards and specialty fruit crops. By offering these frost protection products, FrostDefense aims to help vineyard owners prevent frost damage, thereby enhancing crop yield and improving labor management and mechanized farming operations.
Labby Inc. is a technology company based in Cambridge, Massachusetts, specializing in smartphone-based optical spectrometry for agricultural applications. Founded in 2017, Labby develops an artificial intelligence-driven platform that translates raw optical data into actionable insights, primarily for farmers and dairy processors. Its flagship product allows for rapid and precise testing of milk composition, facilitating early mastitis detection and enabling timely intervention. Additionally, Labby's technology is applicable across various sectors, including the detection of spoilage, adulterants, and contamination in the supply chain, as well as providing analytics for tracking harvest cycles and meteorological data mapping. The company also caters to the beer and wine industries, offering portable testing devices for quality control and counterfeit detection, serving a diverse clientele that ranges from large breweries to homebrewers.
AgroSpheres, LLC is a biotechnology company based in Charlottesville, Virginia, that specializes in innovative pesticide delivery technologies for the agriculture industry. Founded in 2016, AgroSpheres develops engineered bio-particles designed to deliver pesticide-degrading enzymes, which help to minimize waiting periods between pesticide application and harvest. The company employs a unique platform technology that enhances the performance of various crop protection products, including fungicides, insecticides, and herbicides. By utilizing bioengineering and industrial fermentation techniques, AgroSpheres creates biodegradable encapsulation solutions that aim to reduce harmful pesticide residues on plants, ultimately promoting healthier agricultural practices and improving the overall well-being of crops.
Ryp Labs is a company focused on developing and commercializing innovative technologies aimed at reducing food waste. It offers a range of products, including food-safe labels known as Shelf-Defense and stickers called StixFresh. These products are designed to be applied directly to fresh produce or its packaging, effectively prolonging shelf life and freshness by up to two times. By preventing spoilage and over-ripening, Ryp Labs' solutions provide a practical approach for clients to combat the global issue of food waste while extending the usability of their fresh products.
Tender Food is a startup developing plant-based and cultured meat alternatives. Founded by Harvard researchers, they use novel technology to spin plant proteins into fibrous structures resembling real meat's texture.
Kingdom Supercultures
Grant in 2021
Kingdom Supercultures is a Brooklyn-based company established in 2019 that specializes in developing and producing microbial cultures for the food industry. The company focuses on reassembling nature's microbes into innovative combinations, allowing food manufacturers to create new varieties of food with enhanced benefits. Their product line includes Koji, a traditional Japanese ingredient used in miso, sake, and soy sauce, as well as microbial cultures for fermented sodas, beers, and plant-based dairy alternatives. Kingdom Supercultures employs an automated scientific platform that features a comprehensive biobank of Generally Recognized As Safe (GRAS) microbial strains and utilizes advanced algorithms to predict and assemble microbial communities. By providing functional ingredients and biopreservatives, the company aims to support healthy and sustainable food development across various industries, including food, beverage, personal care, and beauty.
Lypid develops vegan fats designed to taste and behave like animal fats. The company uses a novel formulation and microencapsulation to mimic texture, mouthfeel, flavor transfer, and cooking behavior of animal fats, enabling an animal-free alternative with minimal artificial additives, reduced hydrogenation, and fewer trans fats. Its products aim to reduce dependence on animal fats and lower the environmental footprint of food production.
Carrisan Technologies
Grant in 2021
Carrisan Technologies is a food technology company founded in 2019 and headquartered in Davis, California. The company specializes in developing innovative antimicrobial solutions aimed at preventing the spread of foodborne illnesses and minimizing food losses. Its technology encompasses antimicrobial coatings for equipment surfaces, biofilm removal, and production sanitation. These solutions are designed to serve the agriculture, food processing, and foodservice industries, helping to prevent cross-contamination and enhance food safety.
OmniVis is a biotechnology company specializing in pathogen detection. It offers an integrated portable platform that rapidly and accurately identifies pathogens in various environments, reducing the need for labor-intensive lab testing.
Fybraworks Foods
Grant in 2021
Fybraworks Foods, Inc. is a biotechnology company based in Minnetonka, Minnesota, focused on developing alternative meat substitutes through innovative fermentation techniques. Founded in 2020, the company specializes in creating animal-free meat structural proteins and synthetic meat, aiming to replicate the taste and texture of traditional meat products. By leveraging its advanced technological solutions, Fybraworks Foods enables both industry leaders and individual consumers to access sustainable meat alternatives, thus promoting humane practices and reducing environmental impact associated with animal agriculture.
Ubiros specializes in producing electric soft grippers for automation in various industries. Their products, including Gentle Flex Module, Gentle Duo, and Gentle Pro, are designed to handle delicate and irregular items without requiring external air sources, reducing costs, complexity, and noise compared to traditional pneumatic or vacuum grippers.
Pathotrak specializes in rapid food safety testing. Its patented technology reduces detection time of pathogens like Salmonella and E. coli from days to hours, meeting FDA and USDA regulations. This innovation helps minimize holding costs, enables swift recalls, and enhances overall food safety.
Theion Agriculture
Grant in 2020
Theion Agriculture develops fertilizer additives to accelerate the growth of leafy greens grown in indoor farms worldwide. Founded in 2017 and headquartered in Iowa City, Iowa, the company’s additives can be applied to a range of crops, including leafy greens, legumes, and maize, enabling farmers to improve crop yields.
OmniVis is a biotechnology company specializing in pathogen detection. It offers an integrated portable platform that rapidly and accurately identifies pathogens in various environments, reducing the need for labor-intensive lab testing.
Capro-X is an ag-tech company focused on sustainability in the dairy industry. It develops fermentation bioprocess technology to convert acid whey, a dairy waste stream, into valuable products such as bio-oils, biofuels, and bioplastics, while producing clean water. The WheyAway treatment uses naturally occurring, non-GMO microbes to upgrade dairy waste on site at the point of generation. By upcycling acid from dairy waste, Capro-X helps dairy producers reduce waste and improve sustainability and yield over time. Founded in 2017 and based in Ithaca, New York, Capro-X serves dairy processors seeking to turn waste streams into value.
PhylloTech is a biotechnology company focused on producing difficult-to-manufacture proteins and antibodies using a continuous plant expression system based on Nicotiana tabacum. This innovative method allows proteins to be secreted onto the leaf surfaces, where they can be efficiently recovered through a simple washing process with an extraction buffer, thereby eliminating the need for extensive purification. This approach significantly lowers production costs and facilitates rapid scalability, enabling the output of target proteins from tens of thousands of plants. The company's environmentally-friendly system requires only light, water, and fertilizer, making it suitable for cultivation in greenhouses or fields using existing agricultural practices. Additionally, PhylloTech is developing solutions to combat plant diseases by utilizing enzymes to manage bacterial pathogens, which may enhance crop yields and provide alternatives to synthetic pesticides. Through these technologies, PhylloTech aims to contribute to sustainable agriculture by producing high-quality proteins in a renewable manner.
ZestBio develops technology to transform wastes into renewable products by converting agricultural byproducts into specialty chemicals. Through biological processes, it derives value from citrus peels, sugar beet pulp, and grape pomace to produce household cleaning ingredients, bio-based plastics, and vitamins. Based in Berkeley, California, the company was founded in 2017.
Mobius develops environmental solutions that convert industrial organic waste streams into polymers and materials. The company uses lignin, a waste byproduct from the paper and biofuel industries, to produce a natural, biodegradable polymer. This bio-based polymer is intended for applications in horticulture, agriculture, and food service packaging, among others, enabling customers in forestry, paper, biofuel, and biorefining sectors to replace conventional plastics with environmentally friendly alternatives. The approach aims to reduce waste generation and support circular economy goals by turning waste streams from agriculture, forestry, and related industries into new materials and chemicals.
OmniVis is a biotechnology company specializing in pathogen detection. It offers an integrated portable platform that rapidly and accurately identifies pathogens in various environments, reducing the need for labor-intensive lab testing.
Frost Defense
Grant in 2019
FrostDefense, founded in 2018 and based in Champaign, Illinois, specializes in developing innovative frost protection solutions. The company focuses on creating environmentally friendly biofertilizers and patented sprayable compounds designed to combat early spring frost, particularly in vineyards and specialty fruit crops. By offering these frost protection products, FrostDefense aims to help vineyard owners prevent frost damage, thereby enhancing crop yield and improving labor management and mechanized farming operations.
Kingdom Supercultures
Grant in 2019
Kingdom Supercultures is a Brooklyn-based company established in 2019 that specializes in developing and producing microbial cultures for the food industry. The company focuses on reassembling nature's microbes into innovative combinations, allowing food manufacturers to create new varieties of food with enhanced benefits. Their product line includes Koji, a traditional Japanese ingredient used in miso, sake, and soy sauce, as well as microbial cultures for fermented sodas, beers, and plant-based dairy alternatives. Kingdom Supercultures employs an automated scientific platform that features a comprehensive biobank of Generally Recognized As Safe (GRAS) microbial strains and utilizes advanced algorithms to predict and assemble microbial communities. By providing functional ingredients and biopreservatives, the company aims to support healthy and sustainable food development across various industries, including food, beverage, personal care, and beauty.
AgroSpheres, LLC is a biotechnology company based in Charlottesville, Virginia, that specializes in innovative pesticide delivery technologies for the agriculture industry. Founded in 2016, AgroSpheres develops engineered bio-particles designed to deliver pesticide-degrading enzymes, which help to minimize waiting periods between pesticide application and harvest. The company employs a unique platform technology that enhances the performance of various crop protection products, including fungicides, insecticides, and herbicides. By utilizing bioengineering and industrial fermentation techniques, AgroSpheres creates biodegradable encapsulation solutions that aim to reduce harmful pesticide residues on plants, ultimately promoting healthier agricultural practices and improving the overall well-being of crops.
Zebra Analytix
Grant in 2019
Zebra Analytix, Inc. specializes in the development and commercialization of miniature gas chromatography systems utilizing microelectromechanical systems technology, which is exclusively licensed from Virginia Tech University. The company offers innovative products, including the Zebra-GC Model L and Modular Zebra-GC Model M, as well as micro pre-concentrators. Their solutions are designed for various applications, including quality control and safety in the food and beverage industry, environmental monitoring, and uses in the chemical, pharmaceutical, and energy sectors. Founded in 2017 and headquartered in Fayetteville, Arkansas, Zebra Analytix focuses on delivering portable, versatile, and efficient analytical tools that enable businesses to analyze volatile compounds with enhanced speed and precision. Additionally, the company provides services for column refurbishment and custom designs tailored to specific research needs.
Levisonics manufactures blood coagulation instruments for non-contact analysis of blood coagulation and fluid quality control. Its technology enables risk assessments for bleeding and thrombosis, and real-time monitoring of liquid goods' quality during production.
Beta Hatch Inc. specializes in the production of insect protein primarily for animal feed and also produces nutrient-balanced fertilizers as a by-product of its operations. Founded in 2015 and headquartered in Cashmere, Washington, the company focuses on farming mealworms and utilizes rearing technology that converts organic waste, such as spent brewery grains, into high-quality insect feed. In addition to animal feed, Beta Hatch explores the potential applications of insect exoskeletons in bioplastics and pharmaceuticals. With a commitment to sustainable practices, the company aims to create a zero-waste system while addressing the growing global demand for efficient agricultural solutions. Beta Hatch serves a diverse clientele, including farmers, ranchers, and researchers, leveraging its expertise in entomology to promote the use of insects as a viable commodity crop in food and fertilizer applications.
Berkeley Yeast
Grant in 2018
Berkeley Yeast is a biotechnology company founded in 2017 by PhD graduates from Berkeley, located in Oakland, California. The company specializes in engineering yeast strains to enhance the production and quality of various fermented beverages, including beer and wine. By bioengineering yeast, Berkeley Yeast aims to create strains that produce more desirable flavors and minimize undesirable ones, catering to the diverse needs of brewers and winemakers. Additionally, the company develops strains that can reduce ethanol production, facilitating the creation of non-alcoholic beer. Berkeley Yeast's innovations contribute to a sustainable brewing process, supporting the production of not only alcoholic beverages but also other fermented products like bread, cheese, and vinegar, thereby addressing a wide range of consumer preferences in the food and beverage industry.
Farther Farms
Grant in 2018
Farther Farms is a food company focused on sustainable produce and innovative preservation. It provides locally sourced, organic, non-GMO fruits and vegetables and uses technology to improve environmental impact and flavor. The company also develops shelf-stable alternatives to traditionally frozen foods by applying high-pressure processing with dense carbon dioxide at moderate temperatures, a method designed to prevent spoilage without preservatives, chemicals, or genetic modification. This approach aims to reduce costs across the food system, including processing, distribution, and retail, while ensuring convenient, high-quality products for consumers.
OmniVis is a biotechnology company specializing in pathogen detection. It offers an integrated portable platform that rapidly and accurately identifies pathogens in various environments, reducing the need for labor-intensive lab testing.
Founded in 2013, KnipBio develops sustainable biotechnology solutions for animal nutrition. It specializes in creating protein-rich fishmeal replacements, notably KnipBio Meal, to serve the aquaculture industry responsibly.
Capro-X is an ag-tech company focused on sustainability in the dairy industry. It develops fermentation bioprocess technology to convert acid whey, a dairy waste stream, into valuable products such as bio-oils, biofuels, and bioplastics, while producing clean water. The WheyAway treatment uses naturally occurring, non-GMO microbes to upgrade dairy waste on site at the point of generation. By upcycling acid from dairy waste, Capro-X helps dairy producers reduce waste and improve sustainability and yield over time. Founded in 2017 and based in Ithaca, New York, Capro-X serves dairy processors seeking to turn waste streams into value.
ZestBio develops technology to transform wastes into renewable products by converting agricultural byproducts into specialty chemicals. Through biological processes, it derives value from citrus peels, sugar beet pulp, and grape pomace to produce household cleaning ingredients, bio-based plastics, and vitamins. Based in Berkeley, California, the company was founded in 2017.
Secure Food Solutions
Grant in 2018
Secure Food Solutions Inc., established in 2014 and based in Martin, Tennessee, specializes in enhancing global food safety by developing advanced detection technologies for toxins, pathogens, and contaminants. The company's core offering is a patented hyperspectral imaging technology designed to swiftly identify corn contaminated with aflatoxin, aiming to improve food quality and safety worldwide.
Founded in 2013, KnipBio develops sustainable biotechnology solutions for animal nutrition. It specializes in creating protein-rich fishmeal replacements, notably KnipBio Meal, to serve the aquaculture industry responsibly.
Mobius develops environmental solutions that convert industrial organic waste streams into polymers and materials. The company uses lignin, a waste byproduct from the paper and biofuel industries, to produce a natural, biodegradable polymer. This bio-based polymer is intended for applications in horticulture, agriculture, and food service packaging, among others, enabling customers in forestry, paper, biofuel, and biorefining sectors to replace conventional plastics with environmentally friendly alternatives. The approach aims to reduce waste generation and support circular economy goals by turning waste streams from agriculture, forestry, and related industries into new materials and chemicals.
DMC Biotechnologies
Grant in 2017
DMC Biotechnologies, Inc. is a biotechnology company based in Boulder, Colorado, that specializes in the development of bio-based products through microbial fermentation technology. Founded in 2014, the company focuses on engineering microbial hosts to produce a range of specialty chemicals, flavors, fragrances, nutraceuticals, natural products, and pharmaceuticals. DMC Biotechnologies employs its proprietary Dynamic Metabolic Control technology to enhance production efficiency, thereby reducing costs and accelerating the timeline from discovery to commercial performance. The company's innovative approach supports sustainability by utilizing lower energy and resource inputs in the manufacturing process.
Berkeley Yeast
Grant in 2017
Berkeley Yeast is a biotechnology company founded in 2017 by PhD graduates from Berkeley, located in Oakland, California. The company specializes in engineering yeast strains to enhance the production and quality of various fermented beverages, including beer and wine. By bioengineering yeast, Berkeley Yeast aims to create strains that produce more desirable flavors and minimize undesirable ones, catering to the diverse needs of brewers and winemakers. Additionally, the company develops strains that can reduce ethanol production, facilitating the creation of non-alcoholic beer. Berkeley Yeast's innovations contribute to a sustainable brewing process, supporting the production of not only alcoholic beverages but also other fermented products like bread, cheese, and vinegar, thereby addressing a wide range of consumer preferences in the food and beverage industry.
Arch Innotek
Grant in 2017
Arch Innotek, LLC is a biotechnology company based in St. Louis, Missouri, that specializes in engineering microorganisms to produce natural ingredients beneficial for human and animal health. Founded in 2013, the company focuses on developing high-value molecules for various industries, including food, feed, pharmaceuticals, and cosmetics. Arch Innotek employs innovative fermentation processes, utilizing yeast to create natural carotenoid antioxidants and other sustainable ingredients. The company also offers services such as high-performance liquid chromatography (HPLC) analysis, liquid chromatography-mass spectrometry (LC-MS) analysis, protein purification, and molecular cloning, supporting its mission to provide healthier and affordable natural alternatives for consumers.
Carnot Compression
Grant in 2017
Carnot Compression is a manufacturer specializing in energy-efficient air and gas compression solutions, particularly for oil-free applications. The company employs a proprietary isothermal compression process that utilizes water's thermal capacity to absorb heat generated during compression, resulting in significant energy savings compared to conventional methods. By creating millions of tiny gas bubbles surrounded by water, Carnot's technology can absorb substantial amounts of heat, making it capable of delivering low-temperature, oil-free compressed gas. This innovative approach addresses a diverse range of industrial needs, including applications in refrigeration, liquefied natural gas, compressed natural gas transportation, and energy storage. With a focus on sustainability, Carnot Compression is positioned to capitalize on a $30 billion global market opportunity, serving various sectors such as food and life sciences.
Secure Food Solutions
Grant in 2016
Secure Food Solutions Inc., established in 2014 and based in Martin, Tennessee, specializes in enhancing global food safety by developing advanced detection technologies for toxins, pathogens, and contaminants. The company's core offering is a patented hyperspectral imaging technology designed to swiftly identify corn contaminated with aflatoxin, aiming to improve food quality and safety worldwide.
Beta Hatch Inc. specializes in the production of insect protein primarily for animal feed and also produces nutrient-balanced fertilizers as a by-product of its operations. Founded in 2015 and headquartered in Cashmere, Washington, the company focuses on farming mealworms and utilizes rearing technology that converts organic waste, such as spent brewery grains, into high-quality insect feed. In addition to animal feed, Beta Hatch explores the potential applications of insect exoskeletons in bioplastics and pharmaceuticals. With a commitment to sustainable practices, the company aims to create a zero-waste system while addressing the growing global demand for efficient agricultural solutions. Beta Hatch serves a diverse clientele, including farmers, ranchers, and researchers, leveraging its expertise in entomology to promote the use of insects as a viable commodity crop in food and fertilizer applications.
enEvolv, Inc. is a biotechnology company based in Boston, Massachusetts, that specializes in engineering and licensing microorganisms such as bacteria, yeast, and algae for diverse applications across industries including specialty chemicals, food, energy, personal care, and pharmaceuticals. Established in 2011, the company focuses on developing cost-effective and sustainable solutions to meet the growing global demand for critical resources driven by population growth and increased economic prosperity. enEvolv collaborates with various organizations to create novel microorganisms and enhance existing strains to boost production yields and improve product quality. Utilizing a proprietary genome engineering platform based on advanced techniques developed at Harvard, enEvolv accelerates microbial evolution to enable precise genomic edits, offering significant advantages in speed, cost, and engineering capabilities. As of March 2020, enEvolv operates as a subsidiary of Zymergen, Inc.
Spheryx, Inc. is an analytical services and instruments company based in New York, established in 2014. The firm specializes in total holographic characterization technology, focusing on the analysis of colloidal suspensions in various applications, including food, medical diagnostics, consumer products, and quality assurance in manufacturing processes. Utilizing holographic video microscopy, Spheryx characterizes particles suspended in complex mixtures with high precision and reliability. This innovative approach provides customers with valuable insights into the behavior of particulate suspensions, aiding in formulation optimization and quality control. By delivering advanced solutions, Spheryx supports industries in developing safer and more effective products while reducing costs. The company prides itself on its commitment to innovation, driven by a team dedicated to finding creative solutions that benefit both consumers and manufacturers.
RightHand Robotics
Grant in 2016
RightHand Robotics, Inc. is a manufacturer of robotic order-picking systems that streamline supply chain logistics for various industries, including e-commerce, food handling, and flexible manufacturing. Founded in 2015 and headquartered in Cambridge, Massachusetts, the company specializes in robotic solutions that automatically grasp a wide variety of items from bins and cases. Its flagship products include the ReFlex SF, which features a 3D-printed palm equipped with servos and compliant fingers, and the ReFlex TakkTile, a tactile sensor designed to enhance the robots' ability to handle items gently and correct errors. RightHand Robotics focuses on providing end-to-end solutions that simplify integration and adaptation to diverse customer workflows, ultimately reducing the costs associated with order fulfillment across sectors such as electronics, apparel, grocery, and pharmaceuticals.
PhylloTech is a biotechnology company focused on producing difficult-to-manufacture proteins and antibodies using a continuous plant expression system based on Nicotiana tabacum. This innovative method allows proteins to be secreted onto the leaf surfaces, where they can be efficiently recovered through a simple washing process with an extraction buffer, thereby eliminating the need for extensive purification. This approach significantly lowers production costs and facilitates rapid scalability, enabling the output of target proteins from tens of thousands of plants. The company's environmentally-friendly system requires only light, water, and fertilizer, making it suitable for cultivation in greenhouses or fields using existing agricultural practices. Additionally, PhylloTech is developing solutions to combat plant diseases by utilizing enzymes to manage bacterial pathogens, which may enhance crop yields and provide alternatives to synthetic pesticides. Through these technologies, PhylloTech aims to contribute to sustainable agriculture by producing high-quality proteins in a renewable manner.
CinderBio is a company specializing in the development of ultra-stable enzymes derived from microbes that thrive in extreme environments, such as hot volcanic waters. These enzymes are designed to enhance efficiency in existing applications and enable expansion into new markets and industries. CinderBio's products have been tested in various laboratory applications, including proteomics and clinical proteomics, as well as in the food and beverage sector through natural enzymatic cleaning and sanitation solutions. The company has also created a patented one-step process that effectively liberates sugars from cellulosic materials. CinderBio's innovative enzymatic technologies offer significant advantages over traditional methods, including improved performance, cost-effectiveness, and biodegradability, allowing for essential chemical processes to be conducted at lower costs and with greater speed.
DMC Biotechnologies
Grant in 2015
DMC Biotechnologies, Inc. is a biotechnology company based in Boulder, Colorado, that specializes in the development of bio-based products through microbial fermentation technology. Founded in 2014, the company focuses on engineering microbial hosts to produce a range of specialty chemicals, flavors, fragrances, nutraceuticals, natural products, and pharmaceuticals. DMC Biotechnologies employs its proprietary Dynamic Metabolic Control technology to enhance production efficiency, thereby reducing costs and accelerating the timeline from discovery to commercial performance. The company's innovative approach supports sustainability by utilizing lower energy and resource inputs in the manufacturing process.
Carnot Compression
Grant in 2015
Carnot Compression is a manufacturer specializing in energy-efficient air and gas compression solutions, particularly for oil-free applications. The company employs a proprietary isothermal compression process that utilizes water's thermal capacity to absorb heat generated during compression, resulting in significant energy savings compared to conventional methods. By creating millions of tiny gas bubbles surrounded by water, Carnot's technology can absorb substantial amounts of heat, making it capable of delivering low-temperature, oil-free compressed gas. This innovative approach addresses a diverse range of industrial needs, including applications in refrigeration, liquefied natural gas, compressed natural gas transportation, and energy storage. With a focus on sustainability, Carnot Compression is positioned to capitalize on a $30 billion global market opportunity, serving various sectors such as food and life sciences.
Conagen, Inc. is a biotechnology company based in Bedford, Massachusetts, that specializes in synthetic biology solutions aimed at the bio-production of ingredients for the food, pharmaceutical, and renewable materials industries. Founded in 2010, Conagen focuses on the design and optimization of metabolic pathways and production organisms. The company employs advanced engineering techniques and innovative fermentation technologies to enhance its bio-manufacturing capabilities. Its services include strain development, metabolic pathway engineering, fermentation process development, and commercial-scale microbial fermentation, complemented by analytical chemistry and laboratory automation. Through its expertise, Conagen aims to provide clients with tailored solutions that leverage the potential of synthetic biology for various applications.
Founded in 1998, Fiberstar specializes in researching, developing, and manufacturing natural ingredients that enhance food quality and nutrition. Its flagship product, Citri-Fi, derived from orange pulp, offers multi-functional benefits such as moisture management, partial fat replacement, and label-friendly properties. The company's products serve a wide range of industries including bakery, dairy, and meat products.
Acadia Harvest
Grant in 2015
Acadia Harvest Inc. is a seafood cultivation company based in Franklin, Maine, established in 2011. Specializing in land-based indoor marine fish farming, the company utilizes advanced recirculating aquaculture systems to grow high-value fish species such as yellowtail amberjack and black sea bass. Acadia Harvest aims to reduce reliance on traditional ocean fishing by providing sustainable seafood products while promoting innovative technologies in aquaculture. The company operates an integrated facility designed to minimize waste, thereby enhancing the efficiency of its fish farming operations.
SonanuTech specializes in diagnostic solutions tailored for the food and healthcare sectors, leveraging advanced photonic technologies, material science, and nanotechnology. The company operates an in vitro assay platform designed to detect pathogens and biomolecules with exceptional sensitivity, achieving limits of detection in the attomolar range. This proprietary technology significantly reduces assay completion times, enabling healthcare professionals to swiftly identify the appropriate phage treatments within minutes, rather than days. Through its innovative approach, SonanuTech aims to enhance diagnostic accuracy and efficiency, addressing critical needs in pathogen detection and treatment.
Baicor, L.C. is a specialty fertilizer company founded in 1989 by Dr. Gene W. Miller and based in Logan, Utah. The company focuses on the research, development, and manufacturing of fertilizers tailored for various markets, including home and garden, agriculture, greenhouse growing, and golf courses. Baicor is particularly known for its production of liquid fertilizers designed for both foliar and soil applications. These fertilizers are formulated from organic and amino acids that occur naturally in plants and soil, and they are available through a global network of distributors and dealers. As of 2016, Baicor operates as a subsidiary of Brandt Consolidated, Inc.
Founded in 2013, KnipBio develops sustainable biotechnology solutions for animal nutrition. It specializes in creating protein-rich fishmeal replacements, notably KnipBio Meal, to serve the aquaculture industry responsibly.
Spheryx, Inc. is an analytical services and instruments company based in New York, established in 2014. The firm specializes in total holographic characterization technology, focusing on the analysis of colloidal suspensions in various applications, including food, medical diagnostics, consumer products, and quality assurance in manufacturing processes. Utilizing holographic video microscopy, Spheryx characterizes particles suspended in complex mixtures with high precision and reliability. This innovative approach provides customers with valuable insights into the behavior of particulate suspensions, aiding in formulation optimization and quality control. By delivering advanced solutions, Spheryx supports industries in developing safer and more effective products while reducing costs. The company prides itself on its commitment to innovation, driven by a team dedicated to finding creative solutions that benefit both consumers and manufacturers.
Acadia Harvest
Grant in 2015
Acadia Harvest Inc. is a seafood cultivation company based in Franklin, Maine, established in 2011. Specializing in land-based indoor marine fish farming, the company utilizes advanced recirculating aquaculture systems to grow high-value fish species such as yellowtail amberjack and black sea bass. Acadia Harvest aims to reduce reliance on traditional ocean fishing by providing sustainable seafood products while promoting innovative technologies in aquaculture. The company operates an integrated facility designed to minimize waste, thereby enhancing the efficiency of its fish farming operations.
PhylloTech is a biotechnology company focused on producing difficult-to-manufacture proteins and antibodies using a continuous plant expression system based on Nicotiana tabacum. This innovative method allows proteins to be secreted onto the leaf surfaces, where they can be efficiently recovered through a simple washing process with an extraction buffer, thereby eliminating the need for extensive purification. This approach significantly lowers production costs and facilitates rapid scalability, enabling the output of target proteins from tens of thousands of plants. The company's environmentally-friendly system requires only light, water, and fertilizer, making it suitable for cultivation in greenhouses or fields using existing agricultural practices. Additionally, PhylloTech is developing solutions to combat plant diseases by utilizing enzymes to manage bacterial pathogens, which may enhance crop yields and provide alternatives to synthetic pesticides. Through these technologies, PhylloTech aims to contribute to sustainable agriculture by producing high-quality proteins in a renewable manner.
RightHand Robotics
Grant in 2014
RightHand Robotics, Inc. is a manufacturer of robotic order-picking systems that streamline supply chain logistics for various industries, including e-commerce, food handling, and flexible manufacturing. Founded in 2015 and headquartered in Cambridge, Massachusetts, the company specializes in robotic solutions that automatically grasp a wide variety of items from bins and cases. Its flagship products include the ReFlex SF, which features a 3D-printed palm equipped with servos and compliant fingers, and the ReFlex TakkTile, a tactile sensor designed to enhance the robots' ability to handle items gently and correct errors. RightHand Robotics focuses on providing end-to-end solutions that simplify integration and adaptation to diverse customer workflows, ultimately reducing the costs associated with order fulfillment across sectors such as electronics, apparel, grocery, and pharmaceuticals.
CinderBio is a company specializing in the development of ultra-stable enzymes derived from microbes that thrive in extreme environments, such as hot volcanic waters. These enzymes are designed to enhance efficiency in existing applications and enable expansion into new markets and industries. CinderBio's products have been tested in various laboratory applications, including proteomics and clinical proteomics, as well as in the food and beverage sector through natural enzymatic cleaning and sanitation solutions. The company has also created a patented one-step process that effectively liberates sugars from cellulosic materials. CinderBio's innovative enzymatic technologies offer significant advantages over traditional methods, including improved performance, cost-effectiveness, and biodegradability, allowing for essential chemical processes to be conducted at lower costs and with greater speed.
Arbsource specializes in developing and implementing advanced wastewater treatment solutions tailored for the food and beverage industry. Utilizing biotechnology, particularly microbial electrochemical cell technologies, Arbsource transforms wastewater into a valuable resource, thereby significantly reducing clients' water and power expenses.
enEvolv, Inc. is a biotechnology company based in Boston, Massachusetts, that specializes in engineering and licensing microorganisms such as bacteria, yeast, and algae for diverse applications across industries including specialty chemicals, food, energy, personal care, and pharmaceuticals. Established in 2011, the company focuses on developing cost-effective and sustainable solutions to meet the growing global demand for critical resources driven by population growth and increased economic prosperity. enEvolv collaborates with various organizations to create novel microorganisms and enhance existing strains to boost production yields and improve product quality. Utilizing a proprietary genome engineering platform based on advanced techniques developed at Harvard, enEvolv accelerates microbial evolution to enable precise genomic edits, offering significant advantages in speed, cost, and engineering capabilities. As of March 2020, enEvolv operates as a subsidiary of Zymergen, Inc.
SonanuTech specializes in diagnostic solutions tailored for the food and healthcare sectors, leveraging advanced photonic technologies, material science, and nanotechnology. The company operates an in vitro assay platform designed to detect pathogens and biomolecules with exceptional sensitivity, achieving limits of detection in the attomolar range. This proprietary technology significantly reduces assay completion times, enabling healthcare professionals to swiftly identify the appropriate phage treatments within minutes, rather than days. Through its innovative approach, SonanuTech aims to enhance diagnostic accuracy and efficiency, addressing critical needs in pathogen detection and treatment.
C2Sense develops chemiresistive gas sensors for food and agriculture applications, monitoring fruit ripeness and meat/fish/poultry freshness. Its sensors detect ethylene and biogenic amines at low concentrations, helping reduce waste throughout the supply chain.
Acadia Harvest
Grant in 2013
Acadia Harvest Inc. is a seafood cultivation company based in Franklin, Maine, established in 2011. Specializing in land-based indoor marine fish farming, the company utilizes advanced recirculating aquaculture systems to grow high-value fish species such as yellowtail amberjack and black sea bass. Acadia Harvest aims to reduce reliance on traditional ocean fishing by providing sustainable seafood products while promoting innovative technologies in aquaculture. The company operates an integrated facility designed to minimize waste, thereby enhancing the efficiency of its fish farming operations.
Flodesign Sonics
Grant in 2013
FloDesign Sonics is a company that specializes in innovative acoustic technology aimed at transforming the separations and filtration sectors. The firm utilizes 3D non-linear acoustic standing waves to capture, separate, and purify mixtures without the need for physical membranes, chemicals, or centrifugation. This groundbreaking approach has broad applications across various industries, including life sciences, oil and gas, food and beverage, and industrial processing. The primary focus of FloDesign Sonics is in bioprocess separations, where it applies its technology to enhance the manufacturing of life-saving biopharmaceuticals.
Innovesca, LLC is a food innovation company based in Pittsburgh, Pennsylvania, that specializes in developing nutritious ingredients through natural processing. The company focuses on optimizing nutrition from underutilized plants, particularly amaranth, which is processed into a dried, shelf-stable powder for diverse applications. Innovesca's products are designed to enhance the nutritional value of functional foods, such as bars, cereals, and healthy snacks, by unlocking the full benefits of whole foods. By enabling small communities to grow and utilize these nutritional ingredients, Innovesca aims to improve overall health and nutrition while promoting sustainable food practices.
enEvolv, Inc. is a biotechnology company based in Boston, Massachusetts, that specializes in engineering and licensing microorganisms such as bacteria, yeast, and algae for diverse applications across industries including specialty chemicals, food, energy, personal care, and pharmaceuticals. Established in 2011, the company focuses on developing cost-effective and sustainable solutions to meet the growing global demand for critical resources driven by population growth and increased economic prosperity. enEvolv collaborates with various organizations to create novel microorganisms and enhance existing strains to boost production yields and improve product quality. Utilizing a proprietary genome engineering platform based on advanced techniques developed at Harvard, enEvolv accelerates microbial evolution to enable precise genomic edits, offering significant advantages in speed, cost, and engineering capabilities. As of March 2020, enEvolv operates as a subsidiary of Zymergen, Inc.
Excellims Corporation, established in 2005 and headquartered in Acton, Massachusetts, specializes in the development and manufacture of High-Performance Ion Mobility Spectrometers (HPIMS). Their product portfolio includes models like GA2200, MA3100, MC3100, IA3100, and RA4100, catering to diverse sectors such as chemical and pharmaceutical analysis, food safety, security and forensics, research, and petrochemical industries. Excellims also offers Vision Software for controlling instrument operation and data analysis. Their HPIMS products are renowned for their speed, resolution, sensitivity, and field robustness, providing adaptable solutions for various analytical applications in life sciences.
United Science
Grant in 2013
United Science provides food-grade filtration products. They offer scientific solutions, products, and consulting services. They serving the services for mining, oil and gas, and food product manufacturing industries. Their products include filtration media and equipment, separations equipment, and business consulting.
Acadia Harvest
Grant in 2012
Acadia Harvest Inc. is a seafood cultivation company based in Franklin, Maine, established in 2011. Specializing in land-based indoor marine fish farming, the company utilizes advanced recirculating aquaculture systems to grow high-value fish species such as yellowtail amberjack and black sea bass. Acadia Harvest aims to reduce reliance on traditional ocean fishing by providing sustainable seafood products while promoting innovative technologies in aquaculture. The company operates an integrated facility designed to minimize waste, thereby enhancing the efficiency of its fish farming operations.
Porifera develops membrane-based systems for water treatment and product concentration. The company concentrates beverages such as juices, wines, and coffees, as well as other aqueous solutions and challenging wastewater, without pressure or heat, using its membrane concentration technology. Serving the food and beverage industry, Porifera enables production of concentrates that retain all components, improving process efficiency and reducing environmental impact through water purification and waste concentration.
Spectradyn Technologies
Grant in 2012
Spectradyn Technologies provides products including in-line water hardness analyzers, pH/ORP programmable monitors, and free chlorine sensors. Their areas of applications of our analytical instrumentation are environmental monitoring, water quality control, research and development in industrial and academic laboratories, biotechnology, chemical, food, and pharmaceutical industry.
PhylloTech is a biotechnology company focused on producing difficult-to-manufacture proteins and antibodies using a continuous plant expression system based on Nicotiana tabacum. This innovative method allows proteins to be secreted onto the leaf surfaces, where they can be efficiently recovered through a simple washing process with an extraction buffer, thereby eliminating the need for extensive purification. This approach significantly lowers production costs and facilitates rapid scalability, enabling the output of target proteins from tens of thousands of plants. The company's environmentally-friendly system requires only light, water, and fertilizer, making it suitable for cultivation in greenhouses or fields using existing agricultural practices. Additionally, PhylloTech is developing solutions to combat plant diseases by utilizing enzymes to manage bacterial pathogens, which may enhance crop yields and provide alternatives to synthetic pesticides. Through these technologies, PhylloTech aims to contribute to sustainable agriculture by producing high-quality proteins in a renewable manner.
Ecolyse specializes in microbiological products and services across various sectors, including energy, industrial, municipal, and human and animal health. The company focuses on developing ecologically sound and non-toxic solutions for microbial control, addressing issues such as microbially influenced corrosion in pipes, containers, and tanks. Ecolyse employs advanced techniques, including the identification of microbial genomes and the evaluation of biocide effectiveness, with an emphasis on phage-based biocides. Their services aim to provide effective remediation of microbial-induced problems while promoting human health and environmental safety.
Flodesign Sonics
Grant in 2012
FloDesign Sonics is a company that specializes in innovative acoustic technology aimed at transforming the separations and filtration sectors. The firm utilizes 3D non-linear acoustic standing waves to capture, separate, and purify mixtures without the need for physical membranes, chemicals, or centrifugation. This groundbreaking approach has broad applications across various industries, including life sciences, oil and gas, food and beverage, and industrial processing. The primary focus of FloDesign Sonics is in bioprocess separations, where it applies its technology to enhance the manufacturing of life-saving biopharmaceuticals.
MIOX Corporation, founded in 1994 and headquartered in Albuquerque, New Mexico, specializes in the design and manufacture of on-site generators for water disinfection. The company's product offerings include mixed oxidant solutions, mobile chemical-free disinfection systems, and self-cleaning on-site generators. MIOX technologies are utilized across various sectors, including drinking water treatment, wastewater treatment for municipalities and industrial processes, industrial cooling towers, and oil and gas water treatment, including recycling. Additionally, MIOX products serve applications in the food and beverage industry, commercial swimming pools, and legionella prevention in facilities such as hotels, casinos, universities, and hospitals. MIOX operates as a subsidiary of Industrie De Nora S.p.A.
Cerahelix
Seed Round in 2012
Cerahelix designs and manufactures ceramic membrane filters for water purification, resource recovery, and related filtration applications. It offers ceramic microfiltration membranes and housings, including single-channel elements for lab-scale studies and multi-channel elements for commercial-scale projects, as well as filter element housings and laboratory test systems that are sold or leased. Its bio-derived membranes utilize a patented DNA-template technology to form sub-nanometer pores in ceramic material, enabling molecular-level separation of salts, metal ions, and other impurities. The company serves industries such as food and beverage, mining, produced water, fine chemicals, bio-based products, pharmaceuticals, renewables, and waste-to-energy. Founded in 2011, Cerahelix is based in Orono, Maine.