National Science Foundation

The National Science Foundation (NSF) is an independent federal agency established in 1950 and based in Alexandria, Virginia. It is dedicated to supporting research and education in science and engineering across a wide range of disciplines. The NSF provides significant non-dilutive funding, up to $1.5 million, to startups and small businesses through its America's Seed Fund initiative, which is part of the Small Business Innovation Research (SBIR) program mandated by Congress. With an operating budget of approximately $7.8 billion, the NSF is committed to advancing fundamental research and education, thus fostering innovation and technological development in the United States.

James Donlon

Program Director

Debasis Majumdar

Program Director

Graciela Narcho

Staff Associate

Sethuraman Panchanathan

Director

Past deals in Chemical

Aquagga

Grant in 2023
Aquagga, Inc. is focused on combating the environmental and public health threats posed by PFAS, a group of harmful chemicals commonly found in water resources. The company specializes in developing and operating advanced PFAS Destruction units that utilize its proprietary Hydrothermal Alkaline Treatment (HALT) technology. In addition to PFAS destruction, Aquagga is also engaged in creating PFAS Sensing technology and other related solutions for water pollutant mitigation and remediation. The company serves both governmental and municipal markets, as well as the industrial wastewater sector, positioning itself as a leader in addressing the challenges associated with PFAS contamination. Through its innovative approaches and technologies, Aquagga aims to significantly reduce environmental contaminants while promoting positive social impact.

Octet Scientific

Grant in 2022
Octet Scientific is a company focused on developing innovative electrolyte solutions for zinc and other water-based battery technologies. Its flagship products, known as OctoLyte, are designed to enhance the efficiency and extend the cycle life of zinc batteries. By seamlessly integrating into existing electrolyte systems, Octet Scientific's organic electrolyte chemicals significantly improve battery performance across various applications, including backup power, grid storage, portable devices, and mobility. The company's advancements enable clients to create more efficient and cost-effective energy storage solutions, thereby addressing the growing demand for optimized battery technologies in diverse markets.

QSimulate

Grant in 2022
QSimulate is a Boston-based company that specializes in developing cloud-based quantitative simulation tools focused on quantum molecular simulations. By leveraging the principles of quantum mechanics, QSimulate aims to address significant industrial-scale challenges primarily within the chemical and pharmaceutical sectors. Its innovative platform automates various workflows, allowing computational scientists to shift their focus from repetitive tasks to more strategic activities, ultimately enhancing productivity. This approach enables clients to accelerate their research and development processes, positioning QSimulate as a key player in advancing scientific inquiry and innovation in these industries.

Sunchem

Grant in 2022
Sunchem specializes in the development of environmentally sustainable nano filters designed for waste and wastewater management. The company's innovative technology focuses on the selective capture of metals from complex water mixtures, offering a superior alternative to existing separation methods. Targeting high-value markets such as water purification, energy, and critical metal extraction, Sunchem's solutions enable industries to enhance water quality in a cost-effective and energy-efficient manner. Additionally, these filters allow clients to derive value from their waste streams, thereby promoting both economic and environmental benefits.

Belmont Scientific

Grant in 2022
Belmont Scientific is a chemical and battery safety technology company that specializes in process safety and risk management. The company was founded in 2011 and is based in Lowell, Massachusetts.

Environmental Protective Coatings

Grant in 2022
Environmental Protective Coatings, founded in 1983 by Bob Stone and located in Ostrander, Ohio, specializes in the production of innovative coatings designed to protect surfaces from dust and algae. The company offers a range of fluorine-free and omni-phobic coatings that incorporate polymer additives, resulting in self-cleaning properties that help maintain cleanliness by removing dust and preventing algae growth. Additionally, their anti-graffiti solutions allow for easy removal of ink marks, while their coatings facilitate the transfer of viscous fluids in industrial machines, ensuring no residue is left behind. Through these environmentally friendly products, Environmental Protective Coatings enables users to maintain clean and safe surfaces effectively.

Stochastic Research Technologies

Grant in 2022
Stochastic Research Technologies is a software company specializing in providing research and innovative solutions for challenges within the chemical, pharmaceutical, and biomedical sectors. The company focuses on developing algorithms, methods, and tools that address complex issues related to energy and the environment, sustainability, molecular modeling, process management, and supply chain management. By leveraging advanced modeling and optimization techniques, Stochastic Research Technologies enables clients across various industries to effectively tackle biomedical problems and enhance their operational efficiencies. The company's commitment to applied research supports its mission to deliver practical and impactful solutions tailored to the needs of its diverse clientele.

Pyran

Grant in 2021
Pyran LLC is a chemical manufacturing company based in Madison, Wisconsin, specializing in the production of 1,5-pentanediol from renewable wood and crop waste resources, such as corn cobs. Founded in 2017, Pyran develops a starting compound that serves as a raw material for various applications, including paints, coatings, adhesives, biodegradable films, and plastics. The company focuses on replacing petroleum-based chemicals with its renewable five-carbon products, thereby enhancing the performance of everyday materials while promoting environmentally friendly and cost-efficient solutions. Pyran aims to provide the chemical industry with sustainable alternatives that address the challenges posed by diminishing resources and climate change.

Cypris Materials

Grant in 2021
Cypris Materials is a manufacturer and distributor focused on developing sustainable color solutions using non-toxic pigments and dyes. The company offers a structural coating platform that allows both businesses and individuals to redefine color while broadening the color gamut. In addition to its innovative color products, Cypris Materials is creating paintable heat-reflective coatings designed for roofing retrofits applicable to both residential and commercial buildings. By providing environmentally friendly and sustainable color options, Cypris Materials aims to meet the growing demand for eco-conscious materials in the paint and coatings industry.

Tethys Research

Grant in 2021
Tethys Research is a discovery company focused on developing high-value industrial enzymes and chemical entities. Founded to leverage expertise across diverse disciplines, Tethys addresses challenges that traditional high-throughput screening methods cannot effectively resolve. The company collaborates with various organizations to enhance the production and marketing of chemical products and processes, providing innovative solutions tailored to industry needs. Through its contract and partnership models, Tethys plays a significant role in advancing the capabilities of its clients in the chemical sector.

Xheme

Grant in 2021
Xheme is a technology company founded in 2019 and based in Newton, Massachusetts, that specializes in developing advanced blood bag technology aimed at extending the shelf life of blood and platelets. The company also focuses on creating specialty chemicals designed to enhance product quality, sustainability, and safety across various industrial sectors. Xheme's innovative products are programmable, allowing them to provide multiple protective functions such as resistance to oxidation, ultraviolet light, corrosion, and microbial threats. This versatility enables industries to preserve the aesthetic and functional quality of their products over extended periods.

Repela

Grant in 2021
Repela Tech specializes in developing eco-friendly antifouling marine coatings designed to prevent biofouling on ships without the toxic effects associated with conventional copper-based paints. The company's innovative approach involves creating hydrogel coatings and custom-engineered primers that effectively resist a variety of marine micro and macro-organisms, including Ulva zoospores, diatoms, and mussels. This technology offers an environmentally safe alternative to traditional antifouling methods, providing clients with effective solutions for maintaining their vessels while minimizing environmental impact.

CelluDot

Grant in 2021
CelluDot is a biopolymer company focused on developing innovative suspensions and emulsions aimed at addressing agrochemical drift, a significant challenge faced by farmers. The company's platform technology offers a cost-effective and efficient adjuvant that mitigates issues stemming from vapor and particle drift associated with herbicides, such as dicamba. By leveraging wood waste to extract and process nanocellulose, CelluDot produces emulsion technology without relying on petroleum-derived surfactants. This approach not only enhances agricultural efficiency but also contributes to sustainability by utilizing renewable resources.

Phosio

Grant in 2021
Phosio specializes in producing unique chemicals that facilitate the creation of metal oxide thin films using ultraviolet (UV) light at very low temperatures. These metal oxides are utilized across various industries, including semiconductors, batteries, optical coatings, and optoelectronic devices such as displays and solar cells. Additionally, Phosio develops photoresist materials designed to manufacture high aspect ratio nanostructures, focusing on low-temperature production of high-refractive-index optical coatings that are UV curable, transparent, and robust. These advancements support the tech hardware industry in developing smart devices for components like augmented reality, organic light-emitting diode (OLED), and light-emitting diode (LED) technologies.

Sunthetics

Grant in 2021
Sunthetics is a developer of innovative electrochemical reactors designed to enhance the efficiency of chemical manufacturing, particularly in the pharmaceutical sector. By leveraging advanced hardware and machine-learning software, the company enables process chemists to create electrochemical lead molecules in a fraction of the time typically required, achieving process development in one-tenth of the conventional duration. This approach not only accelerates development timelines but also provides significant operational and cost advantages, including a 40% reduction in energy use and the elimination of toxic chemicals and waste. While its primary focus is on pharmaceuticals, Sunthetics' scalable platform technology has the potential to be applied to other markets, such as agrochemicals and specialty chemicals, promoting the electrification of the broader chemical industry.

Quick-Med Technologies

Grant in 2021
Quick-Med Technologies, Inc. is a life sciences company dedicated to developing and commercializing proprietary technologies aimed at infection prevention and control within the medical and consumer healthcare sectors. Founded in 1997 and headquartered in Gainesville, Florida, the company specializes in the research and development of biomedical products and devices with antibacterial applications. Its core technologies include NIMBUS, a family of advanced polymers with antimicrobial and hemostatic properties; Stay Fresh, a chemical formulation for textiles that provides durable antimicrobial protection; and MultiStat, a series of patented methods and compounds for skin therapy. Quick-Med serves a variety of clients, including government agencies and companies in healthcare, medical, apparel, textile, and personal care industries.

Aquagga

Grant in 2021
Aquagga, Inc. is focused on combating the environmental and public health threats posed by PFAS, a group of harmful chemicals commonly found in water resources. The company specializes in developing and operating advanced PFAS Destruction units that utilize its proprietary Hydrothermal Alkaline Treatment (HALT) technology. In addition to PFAS destruction, Aquagga is also engaged in creating PFAS Sensing technology and other related solutions for water pollutant mitigation and remediation. The company serves both governmental and municipal markets, as well as the industrial wastewater sector, positioning itself as a leader in addressing the challenges associated with PFAS contamination. Through its innovative approaches and technologies, Aquagga aims to significantly reduce environmental contaminants while promoting positive social impact.

General Engineering and Research

Grant in 2020
General Engineering and Research specializes in the development of nanotechnology-based systems aimed at both clinical and industrial processing applications. The company's innovative research portfolio includes functionalized nanoparticles and nano-sized capsules that serve various purposes, notably in polishing applications like chemical mechanical planarization. In addition to these polishing solutions, the company also focuses on applications in drug delivery and nano-sensors. By leveraging advanced nanomaterials, General Engineering and Research enables clients to enhance their business processes and achieve specific operational goals.

Pyran

Grant in 2020
Pyran LLC is a chemical manufacturing company based in Madison, Wisconsin, specializing in the production of 1,5-pentanediol from renewable wood and crop waste resources, such as corn cobs. Founded in 2017, Pyran develops a starting compound that serves as a raw material for various applications, including paints, coatings, adhesives, biodegradable films, and plastics. The company focuses on replacing petroleum-based chemicals with its renewable five-carbon products, thereby enhancing the performance of everyday materials while promoting environmentally friendly and cost-efficient solutions. Pyran aims to provide the chemical industry with sustainable alternatives that address the challenges posed by diminishing resources and climate change.

NUMiX MATERIALS

Grant in 2020
NUMiX MATERIALS is a water treatment company that specializes in manufacturing and supplying sorbents to remove dissolved heavy metals from contaminated water. It focuses on RCRA, Water, Sorbents, Pretreatment, and Metals. It was founded in 2018 and headquartered in Chicago, Illinois.

ThruPore

Grant in 2020
ThruPore Technologies Inc., established in 2012 and based in Bear, Delaware, specializes in the development and production of porous carbon support structures for industrial catalysts. The company manufactures heterogeneous catalysts in both pellet and powder forms, with a focus on palladium on carbon reactions. ThruPore's products cater to clients in the precious metal catalysts, carbon-only catalysts, fuel cell, and battery materials industries, offering superior catalysts that enhance dispersion and improve end product refinement.

Benanova

Grant in 2020
Benanova is a company focused on developing environmentally benign nanoparticles (EbNPs) for use in disinfectant, cosmetic, and agricultural applications. Its innovative products combine high efficacy with a degradable design, offering effective antimicrobial and antifungal protection while prioritizing safety for both humans and the environment. Made from natural materials, Benanova's EbNPs demonstrate a significantly higher efficacy compared to conventional nanosilver, paving the way for sustainable alternatives to traditional antimicrobial agents. The company is also working on solutions for environmental remediation and aims to reduce the reliance on chemicals in agriculture by up to 90%, ultimately decreasing the environmental impact and cost of crop protection. Founded on research from experts at NC State University, Benanova is committed to translating scientific advancements into practical, sustainable innovations that benefit consumers, society, and nature.

Membrion

Grant in 2020
Membrion, Inc. is a technology company based in Seattle, Washington, that specializes in the manufacture and commercialization of advanced membranes designed to filter various molecules, including ions, under a wide range of conditions such as temperature extremes, acidity, and biological sensitivity. Founded in 2016 as a spin-out from the University of Washington, Membrion focuses on applications in flow batteries, water purification, fuel cells, and pharmaceuticals. The company’s ion exchange membrane technology, which utilizes silica gel, offers clients membranes characterized by extended lifespans and reduced costs. Membrion has received significant funding from multiple sources, including academic institutions, charitable trusts, and private investors, facilitating the transition from research to commercial production.

SynMatter

Grant in 2020
SynMatter is a company based in Orlando, Florida, founded in 2015, specializing in the development of anticorrosive pigments designed for the creation of smart particles. These pigments are engineered to be integrated into a variety of polymers, including coatings, varnishes, plastics, resins, caulks, putties, sealants, and adhesives. By providing advanced solutions for extended metal protection and antifouling coatings, SynMatter serves industries such as automotive, aerospace, and marine, helping to safeguard vehicles, aircraft, and ships from corrosion.

Kalion

Grant in 2020
Kalion, Inc. is an early-stage industrial biotechnology company based in Milton, Massachusetts, focused on developing glucaric acid and S-3-hydroxybutyrolactone (3-HBL) from renewable sources. Established in 2010, Kalion utilizes green fermentation technology and advanced fermentation methods, employing patented microbes developed through proprietary synthetic biology techniques. The company's innovative approach aims to provide low-cost access to these important molecules, which have significant applications in the industrial chemical, pharmaceutical, and nutraceutical industries. Glucaric acid and 3-HBL have been recognized as key value-added chemicals derived from biomass, with potential in multi-billion dollar markets that are currently constrained by high costs and limited availability. Kalion's mission is to transform the traditional chemical industry by offering sustainable alternatives to oil-based materials, thereby promoting environmental sustainability and chemical purity.

Resource Chemical

Grant in 2020
ReSource Chemical is a company based in Berkeley, California, focused on developing high-performance plastics derived from carbon dioxide. The company utilizes a proprietary bio-based platform to create chemicals that enable the production of environmentally friendly plastics with superior physical properties compared to traditional fossil fuel-based plastics. By converting CO2 into these innovative materials, ReSource Chemical aims to provide sustainable alternatives that do not contribute to environmental pollution.

Octet Scientific

Grant in 2020
Octet Scientific is a company focused on developing innovative electrolyte solutions for zinc and other water-based battery technologies. Its flagship products, known as OctoLyte, are designed to enhance the efficiency and extend the cycle life of zinc batteries. By seamlessly integrating into existing electrolyte systems, Octet Scientific's organic electrolyte chemicals significantly improve battery performance across various applications, including backup power, grid storage, portable devices, and mobility. The company's advancements enable clients to create more efficient and cost-effective energy storage solutions, thereby addressing the growing demand for optimized battery technologies in diverse markets.

Environmental Protective Coatings

Grant in 2020
Environmental Protective Coatings, founded in 1983 by Bob Stone and located in Ostrander, Ohio, specializes in the production of innovative coatings designed to protect surfaces from dust and algae. The company offers a range of fluorine-free and omni-phobic coatings that incorporate polymer additives, resulting in self-cleaning properties that help maintain cleanliness by removing dust and preventing algae growth. Additionally, their anti-graffiti solutions allow for easy removal of ink marks, while their coatings facilitate the transfer of viscous fluids in industrial machines, ensuring no residue is left behind. Through these environmentally friendly products, Environmental Protective Coatings enables users to maintain clean and safe surfaces effectively.

New Iridium

Grant in 2020
New Iridium is a company focused on decarbonizing the chemical industry by converting CO2 into value-added products, thereby reducing overall carbon emissions. The company employs innovative technology that uses photocatalysts and light instead of heat to produce chemicals, resulting in low-energy consumption. By consuming more CO2 than it emits during production and integrating lower-cost alternative feedstocks, New Iridium creates carbon-negative versions of existing commodity chemicals. This approach not only lowers the environmental impact but also offers a cost-effective solution for the chemical industry.

Boydston Chemicals Innovations

Grant in 2020
Boydston Chemicals Innovations, Inc. is a manufacturer of resins and specialty chemicals, established in 2017 and located in Federal Way, Washington. As a subsidiary of 3D Systems Corporation, the company specializes in the development of innovative solutions utilizing ring-opening metathesis polymerization. Boydston Chemicals Innovations produces a variety of chemical products, including polynorbornene, polydicyclopentadiene, and related homopolymers. The company is also engaged in extensive research to enhance the applications of its polymer compounds, offering solutions that incorporate metal initiators such as ruthenium, molybdenum, and tungsten salts.

RenewCO2

Grant in 2020
RenewCO2 is a research company based in Cranford, New Jersey, focused on developing innovative processes to convert carbon dioxide emissions into usable products, such as polymers and organic chemicals. Founded in 2018, the company specializes in clean electrochemical technologies that enable the transformation of CO2 into monomers and other valuable chemicals. By providing solutions that help chemical industry organizations reduce their environmental footprint, RenewCO2 aims to facilitate the creation of sustainable products from waste materials, contributing to a more sustainable future.

Avium

Grant in 2020
Avium develops fuels and chemicals from CO2, water, and renewable energy. The company was founded in 2017 and is based in Lawrence, Kansas.

Benanova

Grant in 2020
Benanova is a company focused on developing environmentally benign nanoparticles (EbNPs) for use in disinfectant, cosmetic, and agricultural applications. Its innovative products combine high efficacy with a degradable design, offering effective antimicrobial and antifungal protection while prioritizing safety for both humans and the environment. Made from natural materials, Benanova's EbNPs demonstrate a significantly higher efficacy compared to conventional nanosilver, paving the way for sustainable alternatives to traditional antimicrobial agents. The company is also working on solutions for environmental remediation and aims to reduce the reliance on chemicals in agriculture by up to 90%, ultimately decreasing the environmental impact and cost of crop protection. Founded on research from experts at NC State University, Benanova is committed to translating scientific advancements into practical, sustainable innovations that benefit consumers, society, and nature.

Emvolon

Grant in 2020
Emvolon is a technology company focused on creating a platform for distributed chemical production that utilizes wasted resources. The company's innovative approach involves converting wasted natural gas from flare sites into usable chemicals, which can serve a variety of industrial applications or be transformed into carbon-negative fuels. Emvolon reimagines traditional diesel engines as miniature chemical reactors, allowing for efficient and effective production without the need for large refineries or chemical plants. This process facilitates the establishment of economically viable small-scale production facilities by leveraging the advantages of mass production alongside economies of scale, ultimately providing communities with the essential raw materials they require.

Cypris Materials

Grant in 2019
Cypris Materials is a manufacturer and distributor focused on developing sustainable color solutions using non-toxic pigments and dyes. The company offers a structural coating platform that allows both businesses and individuals to redefine color while broadening the color gamut. In addition to its innovative color products, Cypris Materials is creating paintable heat-reflective coatings designed for roofing retrofits applicable to both residential and commercial buildings. By providing environmentally friendly and sustainable color options, Cypris Materials aims to meet the growing demand for eco-conscious materials in the paint and coatings industry.

Respondic

Grant in 2019
Respondic is a manufacturing company established in 2019 and located in Champaign, Illinois. It specializes in producing innovative smart adhesive products designed to fulfill various fastening needs. The company's adhesives leverage a unique polymer formulation that provides a strong and permanent bond on diverse surfaces, making them suitable for a wide array of applications. Through its commitment to developing robust and reusable adhesive solutions, Respondic aims to enhance the usability and effectiveness of bonding materials across different industries.

New Iridium

Grant in 2019
New Iridium is a company focused on decarbonizing the chemical industry by converting CO2 into value-added products, thereby reducing overall carbon emissions. The company employs innovative technology that uses photocatalysts and light instead of heat to produce chemicals, resulting in low-energy consumption. By consuming more CO2 than it emits during production and integrating lower-cost alternative feedstocks, New Iridium creates carbon-negative versions of existing commodity chemicals. This approach not only lowers the environmental impact but also offers a cost-effective solution for the chemical industry.

Cyclopure

Series B in 2019
CycloPure, Inc. is a manufacturer specializing in polymer adsorbents designed to eliminate micropollutants from water. Established in 2016 and headquartered in Encinitas, California, the company has developed a pioneering approach using cyclodextrin-based polymer adsorbents for water treatment. CycloPure's products cater to a diverse range of clients, including consumer point-of-use product manufacturers, water treatment operators, engineering firms, medical and commercial enterprises, beverage producers, and textile manufacturers. The company also provides water testing kits through online platforms. To support its innovative endeavors, CycloPure operates a research and technology center located in Skokie, Illinois, positioning itself as a leader in the science of targeted micropollutant removal.

MITO

Grant in 2019
MITO Material Solutions, Inc. is a specialty chemical company based in Indianapolis, Indiana, with an additional office in Stillwater, Oklahoma. Founded in 2016, the company focuses on developing and manufacturing graphene-based hybrid polymer modifiers and additives that enhance material performance across various industries. MITO's flagship product, the MITO T-Series, is a nano-additive that, when mixed with epoxies or resins, significantly improves the toughness of composite parts by up to 100% while reducing the likelihood of mechanical failure by 80%. This innovative solution allows industries such as aerospace, automotive, and marine to either increase the durability of their products or reduce the amount of material used, leading to cost savings and lighter components. MITO's products are applicable to a wide range of materials, including ester resins, BPA and BPF epoxies, and thermoplastics, making them versatile for use in manufacturing processes involving fiberglass, carbon fiber, and other composite materials.

GlycoSurf

Grant in 2019
GlycoSurf, established in 2013, is a specialty chemicals company that produces bio-inspired surfactants, specifically focusing on rhamnolipids. These are high-purity, non-toxic, biodegradable glycolipids with tailored chemical properties. GlycoSurf's products are used in various applications, notably in the formulation of personal-care products, contributing to a more sustainable chemical industry.

Belmont Scientific

Grant in 2019
Belmont Scientific is a chemical and battery safety technology company that specializes in process safety and risk management. The company was founded in 2011 and is based in Lowell, Massachusetts.

Phase Two Chemicals

Grant in 2019
Phase Two Chemicals is a clean chemistry company focused on developing innovative technology for the on-site production of hydrogen peroxide. Through its electrochemical catalyst research platform, the company aims to streamline the hydrogen peroxide production and delivery process. This technology enables clients in industries such as pulp and paper to generate efficient and cost-effective chemical solutions, thereby enhancing their operational capabilities.

Algenesis

Grant in 2019
Algenesis is a material science and technology company based in San Diego, California, founded in 2016. The company focuses on producing renewable and biodegradable polyurethane materials derived from algae and non-food plant oils. Algenesis develops biodegradable foam products, including soft foams suitable for footwear and hard foams designed for surfboards. By partnering with various companies, Algenesis aims to address the global plastic pollution crisis by offering sustainable alternatives to traditional fossil fuel-based plastics. Through its innovative approach, the company contributes to environmental recovery efforts while promoting the use of eco-friendly materials in everyday products.

Millennial Scientific

Grant in 2019
Millennial Scientific is an advanced material and manufacturing company focused on Chromatography and allied products. Our chromatography product portfolio comprises the award-winning NanoPak-C all-carbon suite of products. They deliver high-performance extraction, separation, and purification of chemicals and biochemicals serving underserved or unserved Life- and Bio-Science market segments. These products are available as bulk stationary phase media or packed in solid-phase extraction (SPE) and liquid chromatography columns. NanoPak-C is attracting customers with analysis requirements outside the current silica-based column capabilities and seeking faster, more efficient analysis while reducing laboratory costs and solvent usage. It is benefiting customers seeking next-generation performance capabilities to separate structurally similar compounds, biologics, biobetters, or biosimilars.

Fullmoon Sensors

Grant in 2019
Fullmoon Sensors specializes in the design and deployment of intelligent chemical sensing networks aimed at continuous monitoring of airborne chemicals. Founded in 2018 and based in Palo Alto, California, the company focuses on solutions for detecting volatile organic compounds (VOCs) in the atmosphere. Its patented microfabricated sensors are capable of differentiating, speciating, and quantifying various VOCs while operating efficiently at low power, typically through a USB connection. By utilizing IoT technology, Fullmoon Sensors enables users to identify and measure different low-power gases, contributing to improved environmental monitoring and safety.

H Quest Vanguard

Grant in 2019
H Quest Vanguard develops plasma conversion processes to produce fuels, chemicals, and advanced carbon materials. The company was founded in 2014 and is based in Pittsburgh, Pennsylvania.

Activated Research Company

Grant in 2019
Activated Research Company (ARC), established by Brad Cleveland and Andrew Jones, specializes in developing innovative solutions in the field of catalysis. Its flagship product, the Polyarc® system, combines catalysis with chemical analysis to enhance gas chromatography technology, making it easier to use and integrate into existing systems. This groundbreaking innovation has been recognized internationally, winning awards such as the "2015 Best New Product" at the Gulf Coast Conference and being named one of the top innovations in 2015 by The Analytical Scientist Innovation Awards. ARC's mission is to improve chemical research processes globally through continuous innovation.

Lygos

Grant in 2019
Lygos is a biotechnology company based in Berkeley, California, established in 2011. It focuses on developing sustainable specialty chemicals by engineering microbes to convert sugars into high-value industrial chemicals. The company targets compounds where biological production offers a cost advantage over traditional petrochemical methods. Lygos employs advanced throughput screening and strain construction techniques to optimize pathways for converting inexpensive, renewable feedstock into valuable chemicals. By replacing persistent and potentially toxic chemicals with cleaner, cost-effective alternatives, Lygos aims to provide high-performing, sustainable solutions for business-to-business customers across various industries.

Cyclopure

Grant in 2019
CycloPure, Inc. is a manufacturer specializing in polymer adsorbents designed to eliminate micropollutants from water. Established in 2016 and headquartered in Encinitas, California, the company has developed a pioneering approach using cyclodextrin-based polymer adsorbents for water treatment. CycloPure's products cater to a diverse range of clients, including consumer point-of-use product manufacturers, water treatment operators, engineering firms, medical and commercial enterprises, beverage producers, and textile manufacturers. The company also provides water testing kits through online platforms. To support its innovative endeavors, CycloPure operates a research and technology center located in Skokie, Illinois, positioning itself as a leader in the science of targeted micropollutant removal.

Repela

Grant in 2019
Repela Tech specializes in developing eco-friendly antifouling marine coatings designed to prevent biofouling on ships without the toxic effects associated with conventional copper-based paints. The company's innovative approach involves creating hydrogel coatings and custom-engineered primers that effectively resist a variety of marine micro and macro-organisms, including Ulva zoospores, diatoms, and mussels. This technology offers an environmentally safe alternative to traditional antifouling methods, providing clients with effective solutions for maintaining their vessels while minimizing environmental impact.

SynMatter

Grant in 2019
SynMatter is a company based in Orlando, Florida, founded in 2015, specializing in the development of anticorrosive pigments designed for the creation of smart particles. These pigments are engineered to be integrated into a variety of polymers, including coatings, varnishes, plastics, resins, caulks, putties, sealants, and adhesives. By providing advanced solutions for extended metal protection and antifouling coatings, SynMatter serves industries such as automotive, aerospace, and marine, helping to safeguard vehicles, aircraft, and ships from corrosion.

Pyran

Grant in 2019
Pyran LLC is a chemical manufacturing company based in Madison, Wisconsin, specializing in the production of 1,5-pentanediol from renewable wood and crop waste resources, such as corn cobs. Founded in 2017, Pyran develops a starting compound that serves as a raw material for various applications, including paints, coatings, adhesives, biodegradable films, and plastics. The company focuses on replacing petroleum-based chemicals with its renewable five-carbon products, thereby enhancing the performance of everyday materials while promoting environmentally friendly and cost-efficient solutions. Pyran aims to provide the chemical industry with sustainable alternatives that address the challenges posed by diminishing resources and climate change.

Molecular Glasses

Grant in 2019
Molecular Glasses, Inc. is a company that specializes in developing non-crystallized molecular glasses for use in organic electronics, particularly in organic light-emitting diodes (OLEDs). Founded in 2015 and headquartered in Rochester, New York, the company offers a range of proprietary materials that include hole-transporting, electron-transporting, ambipolar, fluorescent, phosphorescent, and cross-linkable compounds. These materials are designed to be soluble in water and alcohol, as well as compatible with green solvents, making them suitable for various manufacturing processes such as vacuum and solution coating. By providing amorphous and non-crystallizable materials, Molecular Glasses aims to enhance the reliability and longevity of OLED technology, thereby facilitating its adoption in automotive electronics and lighting applications.

Membrion

Grant in 2018
Membrion, Inc. is a technology company based in Seattle, Washington, that specializes in the manufacture and commercialization of advanced membranes designed to filter various molecules, including ions, under a wide range of conditions such as temperature extremes, acidity, and biological sensitivity. Founded in 2016 as a spin-out from the University of Washington, Membrion focuses on applications in flow batteries, water purification, fuel cells, and pharmaceuticals. The company’s ion exchange membrane technology, which utilizes silica gel, offers clients membranes characterized by extended lifespans and reduced costs. Membrion has received significant funding from multiple sources, including academic institutions, charitable trusts, and private investors, facilitating the transition from research to commercial production.

Dynalene

Grant in 2018
Dynalene Inc. is a company based in Whitehall, Pennsylvania, specializing in the development and manufacture of industrial heat transfer fluids and coolants, particularly for ultra-low temperature cryogenic applications. Founded in 1993, Dynalene offers a diverse range of products including glycols, brines, potassium formate, and secondary refrigerants like calcium chloride. The company also produces high-performance coolants and various thermal fluids tailored for specific applications such as HVAC systems, fuel cells, solar and geothermal energy, and food and beverage processing. Additionally, Dynalene provides advanced nanomaterials and lab services, including thermal and chemical testing. Its products are available through an online store, ensuring accessibility for clients across multiple industries.

Dimensional Energy

Grant in 2018
Dimensional Energy is a chemistry company focused on advancing artificial photosynthesis to create environmentally sustainable polymers and chemical intermediates. The company specializes in developing hydrocarbon fuels by effectively harnessing and distributing sunlight through scalable reactor systems. By utilizing innovative, functionalized catalysts, Dimensional Energy's technology enhances the reactivity of carbon dioxide molecules, facilitating their capture and conversion into energy. This approach not only aims to provide viable solar fuels but also supports clients in addressing critical energy requirements while promoting environmental responsibility.

Ambercycle

Grant in 2018
Ambercycle is a material science company focused on transforming textile waste into new materials for brands and producers. By creating a centralized ecosystem for used textiles, Ambercycle addresses the challenges of recycling complex fabrics. The company employs a molecular regeneration technique to isolate components from intricate textiles, producing raw materials from streams that are often difficult to recycle. This innovative chemical recycling technology converts end-of-life textiles into polymer powder, facilitating the creation of new yarns. By enabling apparel businesses to utilize renewable feedstocks, Ambercycle not only reduces waste but also contributes to environmental sustainability.

Algenesis

Grant in 2018
Algenesis is a material science and technology company based in San Diego, California, founded in 2016. The company focuses on producing renewable and biodegradable polyurethane materials derived from algae and non-food plant oils. Algenesis develops biodegradable foam products, including soft foams suitable for footwear and hard foams designed for surfboards. By partnering with various companies, Algenesis aims to address the global plastic pollution crisis by offering sustainable alternatives to traditional fossil fuel-based plastics. Through its innovative approach, the company contributes to environmental recovery efforts while promoting the use of eco-friendly materials in everyday products.

Avium

Grant in 2018
Avium develops fuels and chemicals from CO2, water, and renewable energy. The company was founded in 2017 and is based in Lawrence, Kansas.

Kalion

Grant in 2018
Kalion, Inc. is an early-stage industrial biotechnology company based in Milton, Massachusetts, focused on developing glucaric acid and S-3-hydroxybutyrolactone (3-HBL) from renewable sources. Established in 2010, Kalion utilizes green fermentation technology and advanced fermentation methods, employing patented microbes developed through proprietary synthetic biology techniques. The company's innovative approach aims to provide low-cost access to these important molecules, which have significant applications in the industrial chemical, pharmaceutical, and nutraceutical industries. Glucaric acid and 3-HBL have been recognized as key value-added chemicals derived from biomass, with potential in multi-billion dollar markets that are currently constrained by high costs and limited availability. Kalion's mission is to transform the traditional chemical industry by offering sustainable alternatives to oil-based materials, thereby promoting environmental sustainability and chemical purity.

polySpectra

Grant in 2018
PolySpectra, Inc. is a Berkeley, California-based company founded in 2016 that specializes in the development of computer-guided 3-D printing resins. The company focuses on transforming 3D printing from a prototyping tool into a viable production manufacturing solution. PolySpectra manufactures functional materials for advanced additive manufacturing, utilizing light-activated catalysts to create durable plastic parts suitable for consumer use. Its modular platform allows for the delivery of materials with a wide range of tailored properties derived from a single chemical system. This innovative approach supports inventors, designers, and engineers in bringing their concepts to life.

Benanova

Grant in 2018
Benanova is a company focused on developing environmentally benign nanoparticles (EbNPs) for use in disinfectant, cosmetic, and agricultural applications. Its innovative products combine high efficacy with a degradable design, offering effective antimicrobial and antifungal protection while prioritizing safety for both humans and the environment. Made from natural materials, Benanova's EbNPs demonstrate a significantly higher efficacy compared to conventional nanosilver, paving the way for sustainable alternatives to traditional antimicrobial agents. The company is also working on solutions for environmental remediation and aims to reduce the reliance on chemicals in agriculture by up to 90%, ultimately decreasing the environmental impact and cost of crop protection. Founded on research from experts at NC State University, Benanova is committed to translating scientific advancements into practical, sustainable innovations that benefit consumers, society, and nature.

Millennial Scientific

Grant in 2018
Millennial Scientific is an advanced material and manufacturing company focused on Chromatography and allied products. Our chromatography product portfolio comprises the award-winning NanoPak-C all-carbon suite of products. They deliver high-performance extraction, separation, and purification of chemicals and biochemicals serving underserved or unserved Life- and Bio-Science market segments. These products are available as bulk stationary phase media or packed in solid-phase extraction (SPE) and liquid chromatography columns. NanoPak-C is attracting customers with analysis requirements outside the current silica-based column capabilities and seeking faster, more efficient analysis while reducing laboratory costs and solvent usage. It is benefiting customers seeking next-generation performance capabilities to separate structurally similar compounds, biologics, biobetters, or biosimilars.

Octet Scientific

Grant in 2017
Octet Scientific is a company focused on developing innovative electrolyte solutions for zinc and other water-based battery technologies. Its flagship products, known as OctoLyte, are designed to enhance the efficiency and extend the cycle life of zinc batteries. By seamlessly integrating into existing electrolyte systems, Octet Scientific's organic electrolyte chemicals significantly improve battery performance across various applications, including backup power, grid storage, portable devices, and mobility. The company's advancements enable clients to create more efficient and cost-effective energy storage solutions, thereby addressing the growing demand for optimized battery technologies in diverse markets.

Boydston Chemicals Innovations

Grant in 2017
Boydston Chemicals Innovations, Inc. is a manufacturer of resins and specialty chemicals, established in 2017 and located in Federal Way, Washington. As a subsidiary of 3D Systems Corporation, the company specializes in the development of innovative solutions utilizing ring-opening metathesis polymerization. Boydston Chemicals Innovations produces a variety of chemical products, including polynorbornene, polydicyclopentadiene, and related homopolymers. The company is also engaged in extensive research to enhance the applications of its polymer compounds, offering solutions that incorporate metal initiators such as ruthenium, molybdenum, and tungsten salts.

MITO

Grant in 2017
MITO Material Solutions, Inc. is a specialty chemical company based in Indianapolis, Indiana, with an additional office in Stillwater, Oklahoma. Founded in 2016, the company focuses on developing and manufacturing graphene-based hybrid polymer modifiers and additives that enhance material performance across various industries. MITO's flagship product, the MITO T-Series, is a nano-additive that, when mixed with epoxies or resins, significantly improves the toughness of composite parts by up to 100% while reducing the likelihood of mechanical failure by 80%. This innovative solution allows industries such as aerospace, automotive, and marine to either increase the durability of their products or reduce the amount of material used, leading to cost savings and lighter components. MITO's products are applicable to a wide range of materials, including ester resins, BPA and BPF epoxies, and thermoplastics, making them versatile for use in manufacturing processes involving fiberglass, carbon fiber, and other composite materials.

SAS Nanotechnologies

Grant in 2017
SAS Nanotechnologies is a Wilmington, DE-based company founded in 2016 that specializes in the development of innovative smart and self-healing anticorrosive coatings. These coatings address various chemical challenges across multiple industries, including oil and gas, construction, marine, and architecture. Utilizing advanced micro-capsule technology, SAS Nanotechnologies creates polymer-based microcapsules that encapsulate functional additives like biocides and corrosion inhibitors. These microcapsules release their contents gradually or in response to specific external stimuli, thereby enhancing the functional performance and efficiency of industrial products.

Twelve

Grant in 2017
Twelve, formerly known as Opus 12, is a Berkeley, California-based company that specializes in recycling carbon dioxide emissions into valuable chemicals and fuels. Founded in 2015, the company has developed innovative technology that can be integrated with any source of CO₂ emissions. By utilizing only water and electricity as inputs, Twelve transforms captured carbon dioxide into essential products such as methane, ethylene, and ethanol. The firm aims to provide a cost-competitive alternative to petroleum-derived chemicals and fuels, thereby addressing carbon emissions while simultaneously creating economically viable solutions.

DMC Biotechnologies

Grant in 2017
DMC Biotechnologies, Inc. is a biotechnology company based in Boulder, Colorado, that specializes in the development of bio-based products through microbial fermentation technology. Founded in 2014, the company focuses on engineering microbial hosts to produce a range of specialty chemicals, flavors, fragrances, nutraceuticals, natural products, and pharmaceuticals. DMC Biotechnologies employs its proprietary Dynamic Metabolic Control technology to enhance production efficiency, thereby reducing costs and accelerating the timeline from discovery to commercial performance. The company's innovative approach supports sustainability by utilizing lower energy and resource inputs in the manufacturing process.

Cyclopure

Grant in 2017
CycloPure, Inc. is a manufacturer specializing in polymer adsorbents designed to eliminate micropollutants from water. Established in 2016 and headquartered in Encinitas, California, the company has developed a pioneering approach using cyclodextrin-based polymer adsorbents for water treatment. CycloPure's products cater to a diverse range of clients, including consumer point-of-use product manufacturers, water treatment operators, engineering firms, medical and commercial enterprises, beverage producers, and textile manufacturers. The company also provides water testing kits through online platforms. To support its innovative endeavors, CycloPure operates a research and technology center located in Skokie, Illinois, positioning itself as a leader in the science of targeted micropollutant removal.

Ambercycle

Grant in 2017
Ambercycle is a material science company focused on transforming textile waste into new materials for brands and producers. By creating a centralized ecosystem for used textiles, Ambercycle addresses the challenges of recycling complex fabrics. The company employs a molecular regeneration technique to isolate components from intricate textiles, producing raw materials from streams that are often difficult to recycle. This innovative chemical recycling technology converts end-of-life textiles into polymer powder, facilitating the creation of new yarns. By enabling apparel businesses to utilize renewable feedstocks, Ambercycle not only reduces waste but also contributes to environmental sustainability.

Activated Research Company

Grant in 2017
Activated Research Company (ARC), established by Brad Cleveland and Andrew Jones, specializes in developing innovative solutions in the field of catalysis. Its flagship product, the Polyarc® system, combines catalysis with chemical analysis to enhance gas chromatography technology, making it easier to use and integrate into existing systems. This groundbreaking innovation has been recognized internationally, winning awards such as the "2015 Best New Product" at the Gulf Coast Conference and being named one of the top innovations in 2015 by The Analytical Scientist Innovation Awards. ARC's mission is to improve chemical research processes globally through continuous innovation.

Dimensional Energy

Grant in 2017
Dimensional Energy is a chemistry company focused on advancing artificial photosynthesis to create environmentally sustainable polymers and chemical intermediates. The company specializes in developing hydrocarbon fuels by effectively harnessing and distributing sunlight through scalable reactor systems. By utilizing innovative, functionalized catalysts, Dimensional Energy's technology enhances the reactivity of carbon dioxide molecules, facilitating their capture and conversion into energy. This approach not only aims to provide viable solar fuels but also supports clients in addressing critical energy requirements while promoting environmental responsibility.

Maxterial

Grant in 2017
Maxterial, Inc. is a company based in Richmond, California, specializing in the development of superhydrophobic materials aimed at addressing various environmental challenges such as corrosion, biofouling, and ice formation. Founded in 2015, Maxterial employs advanced chemical and coating technologies to modify the surface shape and texture of materials, resulting in microtextured surfaces that significantly reduce the contact area with droplets and other objects. This innovative approach mimics natural strategies found in nature, such as the self-cleaning properties of lotus leaves and the antifouling characteristics of crabs. The company's coating solutions provide safer and more environmentally friendly alternatives for corrosion prevention and wear resistance, eliminating the need for hazardous chemicals in various manufacturing processes.

LumiShield

Grant in 2017
LumiShield Technologies Inc. is a company based in Pittsburgh, Pennsylvania, that specializes in anti-corrosion products for the metal plating industry. Founded in 2014, LumiShield offers a range of innovative aluminum electroplating technologies, including Lumidize, an aluminum oxide coating designed for the metal pretreatment market. This product enhances the adhesion of paints to various metal substrates and multi-metal components, significantly improving corrosion resistance. LumiShield's solutions are beneficial across multiple sectors, including biomedical, automotive, aerospace, infrastructure, electronics, manufacturing, marine, and consumer goods. The company’s coatings utilize electroplating technology, allowing manufacturers to leverage existing equipment while streamlining their processes and reducing costs. By addressing longstanding environmental concerns associated with traditional methods, LumiShield is positioned to deliver sustainable, cost-effective solutions to its clients.

Ecovia Renewables

Grant in 2017
Ecovia Renewables Inc. is a biotechnology company based in Ann Arbor, Michigan, founded in 2014 as a spin-out from the University of Michigan. The company specializes in developing bio-based ingredients and materials through a proprietary fermentation process that utilizes renewable biomass. Its product offerings include the EcoSynth platform, which produces various biochemical and biofuel products, and Ecovia biopolymers, which are multifunctional, biodegradable alternatives to conventional polymers. The biopolymers are designed for diverse applications, including soil additives for water retention, super-absorbent materials for infant diapers, and thickeners for personal care and industrial products. Ecovia Renewables is dedicated to providing affordable, sustainable solutions that replace petroleum-based materials, contributing to environmentally friendly practices in agriculture and personal care sectors.

enEvolv

Grant in 2016
enEvolv, Inc. is a biotechnology company based in Boston, Massachusetts, that specializes in engineering and licensing microorganisms such as bacteria, yeast, and algae for diverse applications across industries including specialty chemicals, food, energy, personal care, and pharmaceuticals. Established in 2011, the company focuses on developing cost-effective and sustainable solutions to meet the growing global demand for critical resources driven by population growth and increased economic prosperity. enEvolv collaborates with various organizations to create novel microorganisms and enhance existing strains to boost production yields and improve product quality. Utilizing a proprietary genome engineering platform based on advanced techniques developed at Harvard, enEvolv accelerates microbial evolution to enable precise genomic edits, offering significant advantages in speed, cost, and engineering capabilities. As of March 2020, enEvolv operates as a subsidiary of Zymergen, Inc.

polySpectra

Grant in 2016
PolySpectra, Inc. is a Berkeley, California-based company founded in 2016 that specializes in the development of computer-guided 3-D printing resins. The company focuses on transforming 3D printing from a prototyping tool into a viable production manufacturing solution. PolySpectra manufactures functional materials for advanced additive manufacturing, utilizing light-activated catalysts to create durable plastic parts suitable for consumer use. Its modular platform allows for the delivery of materials with a wide range of tailored properties derived from a single chemical system. This innovative approach supports inventors, designers, and engineers in bringing their concepts to life.

Membrion

Grant in 2016
Membrion, Inc. is a technology company based in Seattle, Washington, that specializes in the manufacture and commercialization of advanced membranes designed to filter various molecules, including ions, under a wide range of conditions such as temperature extremes, acidity, and biological sensitivity. Founded in 2016 as a spin-out from the University of Washington, Membrion focuses on applications in flow batteries, water purification, fuel cells, and pharmaceuticals. The company’s ion exchange membrane technology, which utilizes silica gel, offers clients membranes characterized by extended lifespans and reduced costs. Membrion has received significant funding from multiple sources, including academic institutions, charitable trusts, and private investors, facilitating the transition from research to commercial production.

Snapdragon Chemistry

Grant in 2016
Snapdragon Chemistry is a company based in Waltham, Massachusetts, focused on developing continuous flow chemistry solutions for the production of active pharmaceutical ingredients, intermediates, and materials. Founded in 2014, the company offers services including process development, reactor design and build, portfolio optimization, and GMP manufacturing. Snapdragon Chemistry addresses complex chemical transformations to create scalable synthetic processes for clients in pharmaceuticals, chemicals, animal care, and material science industries. The company was previously known as Firefly Chemistry before changing its name in April 2015.

Picoyune

Grant in 2016
Picoyune is a chemical sensing company that specializes in portable detection technologies, primarily targeting mercury, a harmful neurotoxin and widespread pollutant. The company has developed a patented plasmonic film technology that allows for the replacement of extensive laboratory equipment with a compact and user-friendly detector suitable for various operators. Picoyune is also focused on adapting its technology for the analysis of soil and sediment samples from contaminated sites, employing gold nanoparticles to enhance performance and accuracy. By providing high-performance, portable solutions, Picoyune aims to address critical environmental challenges associated with mercury contamination.

GlucanBio

Grant in 2016
GlucanBio is a biotechnology company specializing in the conversion of biomass into valuable chemical products. Originating from research at the University of Wisconsin and Iowa State's Center for Biorenewable Chemicals, GlucanBio aims to produce furan derivatives such as furfural, HMF, DMF, THF, and FDCA more efficiently and cost-effectively than traditional methods. The company leverages its team's expertise in catalysis, intellectual property management, engineering scale-up, and early-stage commercialization, led by renowned catalytic chemist Jim Dumesic and industry veteran Brent Shanks. GlucanBio's innovative technology fractionates biomass under mild conditions to generate solvents directly from the feedstock, facilitating a sustainable approach for clients seeking eco-friendly alternatives.

Polnox

Grant in 2016
Polnox is a company focused on the development of advanced antioxidants, specifically macromolecular antioxidants, aimed at significantly enhancing the longevity of various consumer products and materials. Utilizing its proprietary DT-mPM Antioxidants and eco-friendly McIn Corrosion Inhibitors, Polnox offers products that deliver performance levels that exceed those of traditional additives. The company's innovations provide robust resistance to the damaging effects of heat and oxygen, making its solutions particularly valuable in extending the service life of materials across multiple applications.

Defiant Technologies

Grant in 2016
Defiant Technologies manufactures portable gas chromatograph GC chemical detectors and sensors for VOC analysis in water, soil, and air. The company was founded in 2015 and is headquartered in Albuquerque, New Mexico.

Dynalene

Grant in 2016
Dynalene Inc. is a company based in Whitehall, Pennsylvania, specializing in the development and manufacture of industrial heat transfer fluids and coolants, particularly for ultra-low temperature cryogenic applications. Founded in 1993, Dynalene offers a diverse range of products including glycols, brines, potassium formate, and secondary refrigerants like calcium chloride. The company also produces high-performance coolants and various thermal fluids tailored for specific applications such as HVAC systems, fuel cells, solar and geothermal energy, and food and beverage processing. Additionally, Dynalene provides advanced nanomaterials and lab services, including thermal and chemical testing. Its products are available through an online store, ensuring accessibility for clients across multiple industries.

Advanced Chemical Systems

Grant in 2016
Advanced Chemical Systems provides water treatment services, including boiler maintenance and cooling water treatment, filtration, and purification treatment. Their equipment and chemicals, acids, caustic soda, coagulants and flocculants, filter presses, flow meters, metal precipitants, ph probes, polymers, services, and systems, boiling and cooling systems, dissolved air flotation systems, filtration and purification systems, RO systems, and ph neutralization systems.

Modular Genetics

Grant in 2016
Modular Genetics, Inc. is a biotechnology company based in Woburn, Massachusetts, founded in 2000. The company specializes in designing and developing engineered microorganisms that synthesize chemicals from renewable raw materials, such as sugar. By utilizing a proprietary automated gene engineering system, Modular Genetics focuses on sustainable chemistry, enabling industries to accelerate product development, reduce costs, and facilitate the simultaneous creation of multiple products.

Twelve

Grant in 2016
Twelve, formerly known as Opus 12, is a Berkeley, California-based company that specializes in recycling carbon dioxide emissions into valuable chemicals and fuels. Founded in 2015, the company has developed innovative technology that can be integrated with any source of CO₂ emissions. By utilizing only water and electricity as inputs, Twelve transforms captured carbon dioxide into essential products such as methane, ethylene, and ethanol. The firm aims to provide a cost-competitive alternative to petroleum-derived chemicals and fuels, thereby addressing carbon emissions while simultaneously creating economically viable solutions.

Art of Elements

Grant in 2016
Art of Elements provides custom synthesis of organometallic and inorganic compounds from mg scale up to 1 kg scale. Their custom synthesis undertakings typically involve the synthesis of agreed upon quantities of the compounds using available literature or proprietary experimental procedures at agreed upon purity goals, timing, and pricing terms.

VariFAS Biorenewables

Grant in 2016
VariFAS Biorenewables produces bio-based chemicals for the chemical industry.

AnCatt

Grant in 2016
AnCatt is a pioneering company recognized for developing the world's only heavy-metal free high-performance anti-corrosion coatings. After 50 years of research and development, AnCatt has created the iBarrierTM coating, which not only meets stringent environmental standards but also surpasses existing products in performance metrics, including durability and ease of application. The company offers three product lines: a wash primer system, an epoxy primer system, and a waterborne epoxy system, the latter being the only high-performance waterborne epoxy anti-corrosion paint available. AnCatt's innovative technology utilizes a conductive polymer nano-dispersion to replace hazardous anti-corrosion pigments such as chromate, lead, and zinc, making it suitable for protecting various structures, including steel, pipelines, and bridges. Founded in 2008, AnCatt has scaled its manufacturing processes and holds patents and trademarks in the U.S., EU, and Canada, positioning itself to lead the $30 billion global anti-corrosion coating market through a focus on sustainability and advanced performance.

Foundation Instruments

Grant in 2016
A Foundation Instruments automated chemical analyzer measures trihalomethanes and haloacetic acids in drinking water treatment plants and distribution systems on-site, online, and in real-time. They are chemical analyzers that measure THM concentrations on-line, on-site, and in real time. The company provides drinking water treatment plants and distribution systems.

BrightSpec

Grant in 2016
BrightSpec is a company based in Charlottesville, Virginia, specializing in advanced analytical chemistry solutions through its innovative Fourier transform molecular rotational resonance (FT-MRR) spectroscopy platform. This technology, developed by researchers at the University of Virginia, enables comprehensive characterization of chemical molecules, with the capability to differentiate between stereoisomers and isotopes. BrightSpec's platform addresses high-value, time-sensitive analytical challenges that conventional spectroscopy techniques struggle to meet. By eliminating the need for reference samples or separations, its solutions enhance the analysis of complex mixtures, making them particularly valuable for applications in manufacturing process control, quality assurance, environmental monitoring, and formulation research. The company aims to improve the efficiency and accuracy of chemical analysis, thereby transforming the landscape of sample analytics in various industries.

PolyDrop

Grant in 2016
PolyDrop is a company that specializes in the development of conductive polymer additives aimed at enhancing coatings, composites, and batteries. Originating from the University of Washington, PolyDrop has patented a material science development process that is now utilized by major players in the electronics and coatings industries. The company focuses on creating safe, stable, and affordable conductive polymers that provide anti-static and anti-corrosion protection at low loading levels. These additives enable users to convert conventional coatings and plastics into static dissipative materials suitable for various applications, including textiles, flooring, and marine environments. Through its innovative solutions, PolyDrop aims to improve the performance and safety of existing materials in multiple sectors.

Pyrochem Catalyst Company

Grant in 2016
Pyrochem Catalyst Company, founded in 2010 and based in Louisville, Kentucky, specializes in the development of oxidation and reduction catalysts for automotive emissions abatement and chemical processing. The company’s products facilitate the conversion of natural gas into synthesis gas in challenging environments characterized by high aromatic content, high sulfur levels, and elevated temperatures. By delivering reliable performance over extended periods, Pyrochem's catalysts enable businesses to reduce both capital expenditures and operating costs, thus enhancing efficiency in high-temperature catalytic processes.

Covalent

Grant in 2015
Covalent provides the molecular scale to enable designing, building, and manufacturing with the same speed and cost effectiveness we have at the macroscale. They are an atomic-scale molecular building library. The inside of each block can have a pore.

DMC Biotechnologies

Grant in 2015
DMC Biotechnologies, Inc. is a biotechnology company based in Boulder, Colorado, that specializes in the development of bio-based products through microbial fermentation technology. Founded in 2014, the company focuses on engineering microbial hosts to produce a range of specialty chemicals, flavors, fragrances, nutraceuticals, natural products, and pharmaceuticals. DMC Biotechnologies employs its proprietary Dynamic Metabolic Control technology to enhance production efficiency, thereby reducing costs and accelerating the timeline from discovery to commercial performance. The company's innovative approach supports sustainability by utilizing lower energy and resource inputs in the manufacturing process.

Autonomic Materials

Grant in 2015
Autonomic Materials, Inc. is a manufacturer specializing in self-healing solutions for the coatings industry, primarily focusing on corrosion-resistant chemicals that repair coating damage at the micron level. Founded in 2005 and based in Champaign, Illinois, the company offers a range of microencapsulated additives, including dual capsule systems and single capsule systems, designed for various applications. These products provide essential protection for materials such as metals, wood, concrete, plastics, and composites, and are utilized across multiple sectors, including alternative energy, industrial maintenance, military equipment, infrastructure, oil and gas, transportation, and consumer paints. Autonomic Materials' innovative solutions enable coatings, adhesives, and composites to respond to damage automatically, enhancing the durability and performance of structures like cars, bridges, and ships.

Morphix Technologies

Grant in 2015
Morphix Technologies is a producer of chemical products. Their products include operating instructions,chemicals detected, ammonia,carbon monoxide, chlorine, chlorine dioxide,formaldehyde,glutaraldehyde,hydrazine,hydrogen sulfide, mercury, ozone phosgene, and sulfur dioxide.

Covaron Advanced Materials

Grant in 2015
Covaron Advanced Materials is a seed-stage company based in Ann Arbor, Michigan, that specializes in the development of thermosetting ceramic materials. Founded in 2010, the company focuses on creating patterns, cores, and molds for applications in metal sand casting, plastic thermoforming, and plastic injection molding. Its innovative PETRAFORGE™ technology offers high-performance physical properties akin to traditional advanced ceramics while maintaining the ease of fabrication similar to two-part thermoset polymers. Covaron's products are designed to be environmentally sustainable and serve various industries, including automotive, aerospace, energy, manufacturing, and coatings. The company's advancements in inorganic chemistry aim to provide versatile and effective solutions for constructing ceramic-matrix composites and other applications.
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